LOCUS       DADVXK010000001        79146 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.001, whole genome shotgun sequence.
ACCESSION   DADVXK010000001 DADVXK010000000
VERSION     DADVXK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 79146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.001"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(154..279)
                     /locus_tag="KB909_000001"
     CDS             complement(154..279)
                     /locus_tag="KB909_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836068.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(413..1306)
                     /locus_tag="KB909_000002"
     CDS             complement(413..1306)
                     /locus_tag="KB909_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBB6836069.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1488..2414)
                     /locus_tag="KB909_000003"
     CDS             complement(1488..2414)
                     /locus_tag="KB909_000003"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBB6836070.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2499..3260)
                     /gene="pflA"
                     /locus_tag="KB909_000004"
     CDS             complement(2499..3260)
                     /gene="pflA"
                     /locus_tag="KB909_000004"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBB6836071.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3504..5735)
                     /gene="pflB"
                     /locus_tag="KB909_000005"
     CDS             complement(3504..5735)
                     /gene="pflB"
                     /locus_tag="KB909_000005"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBB6836072.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6012..8462)
                     /gene="parC"
                     /locus_tag="KB909_000006"
     CDS             complement(6012..8462)
                     /gene="parC"
                     /locus_tag="KB909_000006"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBB6836073.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8474..10519)
                     /gene="parE"
                     /locus_tag="KB909_000007"
     CDS             complement(8474..10519)
                     /gene="parE"
                     /locus_tag="KB909_000007"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBB6836074.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10685..11119)
                     /locus_tag="KB909_000008"
     CDS             complement(10685..11119)
                     /locus_tag="KB909_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBB6836075.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11246..11884
                     /gene="plsY"
                     /locus_tag="KB909_000009"
     CDS             11246..11884
                     /gene="plsY"
                     /locus_tag="KB909_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBB6836076.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12016..12891)
                     /locus_tag="KB909_000010"
     CDS             complement(12016..12891)
                     /locus_tag="KB909_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBB6836077.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(12973..13764)
                     /gene="codY"
                     /locus_tag="KB909_000011"
     CDS             complement(12973..13764)
                     /gene="codY"
                     /locus_tag="KB909_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBB6836078.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13782..15182)
                     /gene="hslU"
                     /locus_tag="KB909_000012"
     CDS             complement(13782..15182)
                     /gene="hslU"
                     /locus_tag="KB909_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBB6836079.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15196..15744)
                     /gene="hslV"
                     /locus_tag="KB909_000013"
     CDS             complement(15196..15744)
                     /gene="hslV"
                     /locus_tag="KB909_000013"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBB6836080.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15781..16686)
                     /gene="xerC"
                     /locus_tag="KB909_000014"
     CDS             complement(15781..16686)
                     /gene="xerC"
                     /locus_tag="KB909_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBB6836081.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16884..18260)
                     /gene="trmFO"
                     /locus_tag="KB909_000015"
     CDS             complement(16884..18260)
                     /gene="trmFO"
                     /locus_tag="KB909_000015"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBB6836082.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18229..20307)
                     /gene="topA"
                     /locus_tag="KB909_000016"
     CDS             complement(18229..20307)
                     /gene="topA"
                     /locus_tag="KB909_000016"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBB6836083.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20429..21286)
                     /gene="dprA"
                     /locus_tag="KB909_000017"
     CDS             complement(20429..21286)
                     /gene="dprA"
                     /locus_tag="KB909_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBB6836084.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21342..22109)
                     /locus_tag="KB909_000018"
     CDS             complement(21342..22109)
                     /locus_tag="KB909_000018"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBB6836085.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22102..22962)
                     /gene="ylqF"
                     /locus_tag="KB909_000019"
     CDS             complement(22102..22962)
                     /gene="ylqF"
                     /locus_tag="KB909_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBB6836086.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23222..23620
                     /locus_tag="KB909_000020"
     CDS             23222..23620
                     /locus_tag="KB909_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6836087.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            23899..24399
                     /locus_tag="KB909_000021"
     CDS             23899..24399
                     /locus_tag="KB909_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6836088.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(24482..25033)
                     /gene="lepB"
                     /locus_tag="KB909_000022"
     CDS             complement(24482..25033)
                     /gene="lepB"
                     /locus_tag="KB909_000022"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6836089.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25185..25412)
                     /locus_tag="KB909_000023"
     CDS             complement(25185..25412)
                     /locus_tag="KB909_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6836090.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(25409..25927)
                     /gene="msrA"
                     /locus_tag="KB909_000024"
     CDS             complement(25409..25927)
                     /gene="msrA"
                     /locus_tag="KB909_000024"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6836091.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(25947..26660)
                     /locus_tag="KB909_000025"
     CDS             complement(25947..26660)
                     /locus_tag="KB909_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6836092.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(26663..27559)
                     /locus_tag="KB909_000026"
     CDS             complement(26663..27559)
                     /locus_tag="KB909_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6836093.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(27717..28559)
                     /locus_tag="KB909_000027"
     CDS             complement(27717..28559)
                     /locus_tag="KB909_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6836094.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            28691..29344
                     /locus_tag="KB909_000028"
     CDS             28691..29344
                     /locus_tag="KB909_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6836095.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(29407..29934)
                     /locus_tag="KB909_000029"
     CDS             complement(29407..29934)
                     /locus_tag="KB909_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6836096.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(29954..30901)
                     /locus_tag="KB909_000030"
     CDS             complement(29954..30901)
                     /locus_tag="KB909_000030"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6836097.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(30913..32799)
                     /locus_tag="KB909_000031"
     CDS             complement(30913..32799)
                     /locus_tag="KB909_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6836098.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(32959..35037)
                     /locus_tag="KB909_000032"
     CDS             complement(32959..35037)
                     /locus_tag="KB909_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6836099.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35050..35325)
                     /locus_tag="KB909_000033"
     CDS             complement(35050..35325)
                     /locus_tag="KB909_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836100.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(35687..36142)
                     /locus_tag="KB909_000034"
     CDS             complement(35687..36142)
                     /locus_tag="KB909_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836101.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36296..37504)
                     /locus_tag="KB909_000035"
     CDS             complement(36296..37504)
                     /locus_tag="KB909_000035"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBB6836102.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(37616..37948)
                     /locus_tag="KB909_000036"
     CDS             complement(37616..37948)
                     /locus_tag="KB909_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6836103.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38096..38971
                     /locus_tag="KB909_000037"
     CDS             38096..38971
                     /locus_tag="KB909_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6836104.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39053..39634)
                     /locus_tag="KB909_000038"
     CDS             complement(39053..39634)
                     /locus_tag="KB909_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBB6836105.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(39640..40899)
                     /locus_tag="KB909_000039"
     CDS             complement(39640..40899)
                     /locus_tag="KB909_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6836106.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(40901..41947)
                     /locus_tag="KB909_000040"
     CDS             complement(40901..41947)
                     /locus_tag="KB909_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836107.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42182..42457)
                     /locus_tag="KB909_000041"
     CDS             complement(42182..42457)
                     /locus_tag="KB909_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBB6836108.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(42700..44010)
                     /gene="der"
                     /locus_tag="KB909_000042"
     CDS             complement(42700..44010)
                     /gene="der"
                     /locus_tag="KB909_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBB6836109.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(44192..45421)
                     /gene="rpsA"
                     /locus_tag="KB909_000043"
     CDS             complement(44192..45421)
                     /gene="rpsA"
                     /locus_tag="KB909_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBB6836110.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(45556..46236)
                     /locus_tag="KB909_000044"
     CDS             complement(45556..46236)
                     /locus_tag="KB909_000044"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBB6836111.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(46285..46920)
                     /locus_tag="KB909_000045"
     CDS             complement(46285..46920)
                     /locus_tag="KB909_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6836112.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(46986..48389)
                     /locus_tag="KB909_000046"
     CDS             complement(46986..48389)
                     /locus_tag="KB909_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBB6836113.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(48376..49407)
                     /locus_tag="KB909_000047"
     CDS             complement(48376..49407)
                     /locus_tag="KB909_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836114.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            49438..49659
                     /locus_tag="KB909_000048"
     CDS             49438..49659
                     /locus_tag="KB909_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBB6836115.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(49824..50561)
                     /locus_tag="KB909_000049"
     CDS             complement(49824..50561)
                     /locus_tag="KB909_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBB6836116.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(50714..52054)
                     /locus_tag="KB909_000050"
     CDS             complement(50714..52054)
                     /locus_tag="KB909_000050"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBB6836117.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(52291..53814)
                     /locus_tag="KB909_000051"
     CDS             complement(52291..53814)
                     /locus_tag="KB909_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBB6836118.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(54192..54803)
                     /locus_tag="KB909_000052"
     CDS             complement(54192..54803)
                     /locus_tag="KB909_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6836119.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(54926..55051)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(55133..55849)
                     /locus_tag="KB909_000053"
     CDS             complement(55133..55849)
                     /locus_tag="KB909_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6836120.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(55855..56424)
                     /gene="scpB"
                     /locus_tag="KB909_000054"
     CDS             complement(55855..56424)
                     /gene="scpB"
                     /locus_tag="KB909_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBB6836121.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(56408..57205)
                     /locus_tag="KB909_000055"
     CDS             complement(56408..57205)
                     /locus_tag="KB909_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBB6836122.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(57175..57546)
                     /locus_tag="KB909_000056"
     CDS             complement(57175..57546)
                     /locus_tag="KB909_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6836123.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(57565..58452)
                     /gene="xerD"
                     /locus_tag="KB909_000057"
     CDS             complement(57565..58452)
                     /gene="xerD"
                     /locus_tag="KB909_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBB6836124.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(58548..59021)
                     /locus_tag="KB909_000058"
     CDS             complement(58548..59021)
                     /locus_tag="KB909_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6836125.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(59126..59989)
                     /locus_tag="KB909_000059"
     CDS             complement(59126..59989)
                     /locus_tag="KB909_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6836126.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(60185..62284)
                     /locus_tag="KB909_000060"
     CDS             complement(60185..62284)
                     /locus_tag="KB909_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6836127.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(62504..63613)
                     /gene="rpoD"
                     /locus_tag="KB909_000061"
     CDS             complement(62504..63613)
                     /gene="rpoD"
                     /locus_tag="KB909_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBB6836128.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(63637..65478)
                     /locus_tag="KB909_000062"
     CDS             complement(63637..65478)
                     /locus_tag="KB909_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBB6836129.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(65660..67975)
                     /locus_tag="KB909_000063"
     CDS             complement(65660..67975)
                     /locus_tag="KB909_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6836130.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(68160..69020)
                     /locus_tag="KB909_000064"
     CDS             complement(68160..69020)
                     /locus_tag="KB909_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBB6836131.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(69079..69600)
                     /locus_tag="KB909_000065"
     CDS             complement(69079..69600)
                     /locus_tag="KB909_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6836132.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            69878..70639
                     /locus_tag="KB909_000066"
     CDS             69878..70639
                     /locus_tag="KB909_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6836133.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            70665..73256
                     /gene="mprF"
                     /locus_tag="KB909_000067"
     CDS             70665..73256
                     /gene="mprF"
                     /locus_tag="KB909_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6836134.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(73444..74631)
                     /gene="tuf"
                     /locus_tag="KB909_000068"
     CDS             complement(73444..74631)
                     /gene="tuf"
                     /locus_tag="KB909_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6836135.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            74999..75355
                     /locus_tag="KB909_000069"
     CDS             74999..75355
                     /locus_tag="KB909_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6836136.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(75596..76600)
                     /locus_tag="KB909_000070"
     CDS             complement(75596..76600)
                     /locus_tag="KB909_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBB6836137.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            76766..77617
                     /locus_tag="KB909_000071"
     CDS             76766..77617
                     /locus_tag="KB909_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6836138.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            77634..77879
                     /locus_tag="KB909_000072"
     CDS             77634..77879
                     /locus_tag="KB909_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836139.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            78066..78770
                     /locus_tag="KB909_000073"
     CDS             78066..78770
                     /locus_tag="KB909_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836140.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        21817 a        16625 c        13607 g        27097 t
ORIGIN      
        1 aaaagcattt tgaagcctga ctattacgac ttcataaatg cttttttagt tttaaacact
       61 tcaatctaaa agaataaccc aagattggat aaattattaa tgactcgcca ttcgtttctt
      121 agtgattctg gattatcaaa tggacttcct aatctaatca gctagttctt cccataaaat
      181 gccatacttg actgaatcat aatattgatt atttaaaaat ctaacttttc ttatcactac
      241 ttcctttgtc attccacatt tctcaccatt tttttgcatt cctttgtttc cagaccatgt
      301 agtgaatcta ataggtggta gataggcaaa atactcaaat aattctttta accataaagg
      361 aagagaaagg ctcctcctgc aagagtcagt ataatttttg cttactgctc tcttaggttt
      421 tactcactaa aactgttcca tattctttga tataagaaaa tgcatgcggt ataaatttct
      481 tgctcagctc agaaaagatt tgtcgtttaa gaaaggccat ttcctccatt gtcaatgaag
      541 gatccaatgt tggtaattca atctcaaaat tgtttttttc gacaataggt aattctaatg
      601 tgaatgattc ttcttccttt atagtattcg tcacaagtag agactgatgg aaaatactag
      661 gccggcgatt tttatattta ttcttacgta tcctgtcaac gataacttct atttgatcaa
      721 aaaagtacga ttcatttacg tctccaataa gttcggctaa ttctttgaat gccttcgtta
      781 caggaagctg attcttctgt acaaaaaagt aattagccaa agtaagcggg aagtgttcta
      841 tagaggaaag tgtgataaaa cggtacttct catttcctgc agttgtcctc agcaattctg
      901 tctctcggct gtttcttact ccataaaaat acgcttcttt ccgttcatct tcgaaacaat
      961 acgcccaaat aacttctccc atcgctaatt tttgttcatc aacagagagt ctcttcaatt
     1021 gttcagctat ggtttcagca gccgaagtgg cttgttgcaa gtaatcttta ggatcaaata
     1081 ttggaaagtt caaatgatat cttcgttctt ccctcttgat taatcctgca tcgatcaata
     1141 aatcaagaaa atgggaaaat ttattttgcg aaaattcttt tttcaattct cttagaatcg
     1201 tttcttgttc tcgatgttca tatagataat cggtcaatga agaaaaaagc ggatcatcgg
     1261 tcagtttttg ataaaagttt tccttatttt ttgaataata gttcatatat gttctctttt
     1321 ctatccgttt tattttactt aaaaggcttt tacgtaaaaa ggaggaagaa caagagtcat
     1381 aattgactgt tattctcctc catttcttcg gcctttagta tgttctatgt ttctttttat
     1441 atcaatcgct tatccattca ttttgaatgc ttcatactac catttgatta gctaaataca
     1501 gccgtcaatt gaggtacgac ttgtttttta cgtgaaacga cacctttaag caaagcacgg
     1561 ttgttggtca aagttgtttg gaaagcttct tctacttttt cttttccttt accagcaaca
     1621 agtaattctg aatcactgtc taagatgttt gtgacaacta atacgaacag atcgtagcca
     1681 tttgctttca tttcatcttc cattgctgct tctagctctg cttgtcgatc catcacttca
     1741 ttaaggtcca ctgtattgac ttgagcgata cgaacgttgg aactgcccat tgggaaactt
     1801 tttgcatcca aatcaagaag aaccgcagct gatttatcac ttagatttgt tcctgctttc
     1861 aacatttcaa gtccataagt gtttagatcg acttcagcga ttgctgcaag ttcttttgca
     1921 gctgcttcat cttcaggcgt acatgttggt gatttgaaca acaatgtatc tgaaatgata
     1981 gctgagagca tgattcctgc gatttcttta ggaattgtta cttggttttc tttatatagt
     2041 tttaaaataa tcgtacttgt acatccaact ggttctgcac gatagtacaa tggattagct
     2101 gtttcaaagt ttgcaatacg atggtggtct actacagcta aaatatttac ttcgctgata
     2161 tctgaaatac tttgttggaa ttcattatga tccacaagca tgacatctgc attttctgct
     2221 ttagctgact ctactactcg tggtgcagat agctgaaagt ggtctaatgc gtattgtgtt
     2281 tcttcattag gtgtacctag agcaactgct tctgtttctt tacctaattc attttgcaag
     2341 tgtgaaaacg caatggctgc cccgattgca tctgtatctg gattttggtg accaaaaact
     2401 aaaatttttg acatgtcatt cgctcctttg tgatttctcc tatttaataa tagcaaaaaa
     2461 acggaaagaa gcaatactta tcttctttcc gatgcgacct atcgcgttaa atattttgta
     2521 tactcttctg tatgaagcaa tcgtttagca ttttcgacac gttcttttgt aggtggttcg
     2581 atcccttcta atggatattt caaaccaagt gtttcccact tgtattttcc catcgtatga
     2641 taaggaagaa tctctactct gtctacattt gacaaggttt gaataaagtt gtctagtcgg
     2701 atcaaatatt catcataatc acttcgctca ggaactagta catggcgaat ccaaaccggt
     2761 ttgttgattt ttgacaaata ttgagccatt tctaaaatat tttcattgtc ccaatgcgtt
     2821 agttttttat gctcttcatt atcgatgtgt ttgatgtcaa ataacagtaa atctgtatac
     2881 ttcatcaatt cttgaaaacg tgaaaagaaa ggttcttcat acgtaaaagg ttttccgcat
     2941 gtatccaatg tagtatgcat cttccgctct tttgcttttt taaatagttc gatcaaaaaa
     3001 tcgatctgca atagaggttc tccaccacta acagtaatac cacctttatc tccccagtaa
     3061 ggtctgaagc gttctgcttt atctaaaagt tcatctgctg tgtattcttt ccctccgcca
     3121 atattccaag tatctggatt gtgacaaaat tggcaacgca tgcggcatcc ttgcataaac
     3181 acgacaaagc gcagtccagg tccgtctact gaaccgaaag tttcgataga atgaacatag
     3241 ccgattgttt tttcttccat ttaagttcac atcttttctt tgatttcatt ttaagtacaa
     3301 gttagctgtc gaagcgaagc tttctgaaca aaatttttcg caattgccgc ttcgttatgt
     3361 gtaaaattta cagggacgga acatacaagt cctgcccctg taaatcgttt ctttcaaata
     3421 agcatactga ttattcgatt ttgatgcgat ggctattcaa cgtcctttcg acgctaagtc
     3481 gaaaaacttt tttcacgaac tttttacatt ctgtcgtgtg aagttctcat caagacatct
     3541 aattgttgtt ctcttgtcaa gtcacggaat ttaactgcat aaccagatac ccggatcgtc
     3601 aagttcggat atttcattgg attttccatt gcatcacgca ataaatcatt actgaataca
     3661 ttgacattca aatgataagc tccttttgag aagtatccat ctaagacatt acgcaagttt
     3721 tcgattcttg tatcttgttc ttttccaaga cctgaaggat tgattgtttg ggtatttgaa
     3781 attccatcca atgcacagcc gtaattcatt ttagctgttg agttcaggct agctaataac
     3841 ccactttgtt ccgcattgta acttggattt gctcctggcg caagtggttt tccagcttca
     3901 cggccatcag gagtatttcc tgtattttta ccgtaaacaa catttgaagt aatcgtcaat
     3961 aatgaagttg ttggttttga gttgcggtaa gttttatgac gtttgatttg tcccatgaag
     4021 tattccaaga tccatgaaac taattcatct gcacggtcat catcatttcc gtatttaggg
     4081 aagtcgccat ccacttcaaa atcaactgct attccttttt cattacggat tgcttttact
     4141 tttgcatatt tgatcgctga caagctgtct gccgcatgag agatcccagc aatacctgta
     4201 gcaaatgtgc gttgcaagtc agaatccatc aaagccagct gagctgcttc ataagaatat
     4261 ttatcatgca tataatgaat gatgttcaac gtattgacat atagttctgc taaccaatcc
     4321 atcatattca tgaagttatg tttcacttct tcaaagtcta gtatttctga tgtgattgga
     4381 cgatattctg gtccaacttg ggcgccagtc acttcatcga ctccgccatt gatggcatat
     4441 aatagtgttt tagccaagtt agcacgagcg ccaaagaatt gcatgtcttt tccgacaact
     4501 gttcctgata cacagcaagc aatcgcacaa tcatcagaac cccattgttc acgaagctga
     4561 ttatcatttt cgaattgaat cgaagaactt tcgatagcga ttctgctagc atatgttctg
     4621 aatccttctg gaaggtgttc agaatacaaa acagtcaagt ttggttctgg tgaaggtccc
     4681 atatttgtta atgtatgaag cagacggaaa tcattctttg taactaatga acgaccatct
     4741 aatcccatac ctgcaatgga taaagtagcc cagataggga atcctgagaa taattggtta
     4801 tattcaggtg tacgcgcgaa tttgaccata cgtaatttca ttactaagtg gtcgatcaat
     4861 tcttgtgctt ctttttctgt gattactcca ttatccaaat cacgttggat atagatatca
     4921 aggaatgctg agatacgtcc gattgacatc gcagcaccat tttgtgattt gattgctgct
     4981 aaatatccga agtatagcca ttggacagct tcttttgcat ttgcagctgg tttagaaata
     5041 tcatagccat atttcgcagc catttctttc atttgcgcta atgcacgata ttgttcagtg
     5101 atttcttcac gtaaacgaat cacttcttca ctcattgtat gataaccagt catatcatga
     5161 tcttttttct tttgttccat caaatagtcg attccataca atgccacacg acgatagtca
     5221 ccgatgatac gtccgcgacc gtaagcgtct ggaagccctg taatgatttt gtttttacga
     5281 gcagcacgca tttcagcagt ataagcgtca aatacacctt gattatgtgt tttgcgccag
     5341 tcagtgaaaa tatgtgtcaa ttcatcgttt ggtgtatagc cattgctttt tagcgcattg
     5401 ttagccatat tgattccgcc gaacggcatg aatgcttgtt tcaaaggttt gtctgtctgt
     5461 agaccgacga ttttttccaa atctttatcc aaatagcctg catcgtgtga agtaatagtt
     5521 gatacgattt ctgtgtccat atcatagaca ccgttacgct cgaattggat atcatttaac
     5581 ttttgcaatt catcccataa tttttctgtt gcttctgttg ggccttccaa aaagctgtca
     5641 tcaccgcgat attcagtgta gttattttga ataaagtctc tagtgtctac gccttctttc
     5701 catttggtac ctttaaatcc attccattgc tccattgtat ggacctccta aatttctgtt
     5761 ttatgtaaca gtttttacgt gattagtata acacagcacc ctatctttgc aagggttttc
     5821 ttgtttttta tttaacaatt tttatgtttt atttacatat atttaaatca acgttgacat
     5881 accaacattt aagcattgtg aacactttca tctttttttg caaacgtata aggatttatt
     5941 aaaaatgaat gaaaaagaga cgccacctgt attaatacag atggcgtctc ttcattaaaa
     6001 tactacaaca gttacgactc gatgaaaatc tcaggagcat cgataacttc gatgacttct
     6061 ccaccttttt tctcatccat cgcaaatgat ccattcgatg ttcgatcacc tatagggaaa
     6121 tcagttgggt caatcgttaa ctgctgccct ttttgattca tcaaggttat ttcttttgat
     6181 cttccttccg acatatagat aatacggtgc ggattttttt tcagctcacg catgaccgtc
     6241 actccccgct tcgcacgtga agtttggctg atttcttgag caagcatgcg tttaacagct
     6301 cctcgctgag taacgattac gatcggcgta tcaccttctg ctaacacaag cagcccgttg
     6361 ataatcctat ctccatcttt caaattcata gacttcactc cagctgcctt tgctccaaca
     6421 acgggaacat ctgttaaagg atagcgcaaa cccattcctt gatgcgttac taagaaaaca
     6481 tctaagcctg gctgatcttc tttcagatac acagcaatca gttcatcttc ttccgccttt
     6541 agcttcatac agctgagcgg acggctctta taggtgcgcc atggttcgaa ctctgtcatt
     6601 cgtgtttgct tgatcaatcc attcttgctg atgaatacaa atgttttctc tgcttgaatt
     6661 ttttgatatg ggaaaacagc taaaatcgat tcgtctacag acagattgga gattgtttga
     6721 gaaatgtgct caccagcatc tttccatttc aaatcgggta gttcatggac agggcggtag
     6781 atcacatttg ctttatttgt gatcagaaga acatggtcca atgtactcaa ttcacctgag
     6841 tatagcaagt agtcgccttc tcgcatcccg atttcttctg gtttggaagc actataagaa
     6901 cgaaggcttg ttcgcttcac atagccttct cgcgtcacac tgacaattac gtcttcttgt
     6961 gccactaaga cttgcgtatc aattttgatt tcttcgattt cgtcttcgat tgtcgttaga
     7021 cgagcggaag aataattttt tttcacttct cgcaattctt ttttcataac agagaaaagc
     7081 tctttgtcat ttgaaaggat tttattcaac tctgtgattt gcgcaatcaa gctttcggat
     7141 tccttttgaa gctctgtgat atccgtgttc gtcaaacggt ataattgcaa tgtgacaatt
     7201 gcttctgctt gttcttctgt aaattgaaag acgtcgacta aattcttttt ggcgtctttt
     7261 ttgtctttac tttcacgaat cgttgcgatt acttcatcca gaatcgataa agctttcatc
     7321 aatccttcta cgatatgctg tcttttttga gctttggcta aatcgaattg actacgtttt
     7381 gttatgactt gctttcgatg ctcgatataa cttcttaaaa tgtctttcag tccaacttga
     7441 tgcggagtca tatggtcgat agcgaccata ttgaaattgt aattgatctg tagctcagtg
     7501 tttttgaaca aataattcaa aattccttga gcattggcgt cttttttcaa ttcgacgaca
     7561 atttgcagac ctgttctatc actttcatct cgtacttcag ctattccatc gattttctta
     7621 ttcaaacgga tctcatccat ttttttcacc aaggtcgctt tatttacttc atatgggatt
     7681 tctgtgatca cgatttgctg tttattaccc ttcattgcct ctatctttgt tttcgaacga
     7741 agaataactt ttcctcgtcc tgtttcataa gcttttttga tttcatcttt tccttgcaag
     7801 atccctcctg ttggaaagtc aggtccagga atatattcca tcaatttttc aaggctcgct
     7861 tgtggatgat cgatcatata gattgtgcca tcgatcactt cagctaagtt atgagtcggg
     7921 atttctgttg catatccagc agatatacct gtcgatccat tgacgagaag gtttgggtat
     7981 cgagctggaa ggactgttgg ttctttttct gtatcatcaa aattccacac gagatcgact
     8041 gtttctttct cgatatctgc tagcatctct ccacttaact tggataatct ggcttcagta
     8101 taacgcatcg cagcaggtgg atcaccgtcc atactcccgt tattcccgtg catttcgatc
     8161 agtacttccc gcaacttcca gtcttggctc atgcggacca tcgcttcata aatactgatg
     8221 tcaccatgag gatgataatt ccccatgata tttccgacag attttgctga tttacggaat
     8281 cctttgtcat acgtattgcc atctttgttc atggcaaata atatccggcg ttgcactggc
     8341 ttcaatccat cacggatatc aggcagtgca cgttcttgga taatatattt ggaataacgt
     8401 ccgaagcggt cacccatcac ttcttctaaa gttaattctt gtacttcttg tcgattttcc
     8461 atcaggtgac ctcctattct acttcaaata actgattgtt ttcattttta tctgctcgtt
     8521 cttcatctaa taaatcatta gaaactgaag gagagatttc agtatcctct tttttatcta
     8581 agatactgcc atcttcttcg agcgtaaatt gcacgtgatt ttcgatccat tttcttcgag
     8641 gttctacttt gtcacccatc agtgtggtta ctcgacgttc agcttgcgca gcatcatcga
     8701 tacggacgcg gatcaacgta cgggaagtcg gatccatcgt tgtttcccac aattgttccg
     8761 cattcatctc tccaagtcct ttatatcgct gcagcatata tcctttgccg acttttttaa
     8821 tcattgctgc caattcgtca tctgtccacg catattcaat gacttgcttc tttccttgtc
     8881 ctttggatac tttatataaa ggcggtaacg cgatatatac tttcccagct tcaatcagcg
     8941 gtttcatata acgataaaag aaagtaagca gtaatacttg aatatgggcg ccgtctgtat
     9001 ccgcatcggt catgatgatt actttgtcgt aattacagtc ttcgatagaa aactcaggac
     9061 cgactcctgc accaatcgta tagatcatcg tattgatttc ttcatttttc aagatatctt
     9121 gcattttagc tttttcggta ttgatgactt ttcctcgtaa aggtagaatt gcttggaact
     9181 ttctgtctct tccttgttta gcagatccgc cagcagaatc cccttcgact aaatacaatt
     9241 catttttctt agggtttcgg gattgtgcgg gtgtcaattt tcctgaaaga agagattcgc
     9301 cttttttacg cttcttccca tttcggcttt cttctctggc tttacgtgct gcttctctcg
     9361 cttctctggc tttgattgct ttacggacca acatctggct catttcgcta ttttcctgca
     9421 aataaaagcc catttgttca ctgatgacgt tatctactac ggtacgagca actggcgtac
     9481 caagtttttc ttttgtttgc ccttcaaatt gcagaagatt ttcaggtaca cggatagaaa
     9541 gtacagcagc taacccttct ctgaaatcac taccttccag attcttgtcc cgttctttca
     9601 gcaaaccaac ttttctcgca tattcattat aagatttcgt catcgccgct ttcataccag
     9661 cttcatgggt tcccccatct tttgtccgaa cgttattgac aaaagataaa acattttctg
     9721 aataaccgtc attgtattga taagcgacct ctacttcgat accttctttt tctcctgaaa
     9781 aataaacaac tggtgtcaat gtatcttttt cttcattcag ataatcaaca aattctttga
     9841 ttccttcttc gtaatgaaaa atttccttga ctggttcttc tccacgaaga tcagaaagag
     9901 agattttaac gccttttaga agaaaggcag attctcttaa ccgttcggct aaaatttcat
     9961 atgaaaattt cgttgtactg aatattgtat catctggtaa aaaatggaca gtcgtcccgt
    10021 ttgctttttt tgtttttcct atctttttca aagtaccgtc aggtttaccg ccgtttttaa
    10081 atttctgctg atactctacg ccatctctaa cgatcgttac aattagccat ttcgataagg
    10141 catttaccac actggctcct acaccgtgca gtccaccaga agttttgtac cctccttgac
    10201 caaactttcc gccagcatgc agcacagtaa aaatcacttc aactgttggt attccggaag
    10261 catgcattcc tacaggcatc ccacgtccgc tatctgcaac agttatacta ttgtcttcat
    10321 ggatggtcac atcaatctca ctgccataac ctgataatgc ttcgtcaact gcattatcga
    10381 cgatttcata gactaaatga tgcaagcctc ggctgtcagt ggatccaatg tacatccctg
    10441 gtctttttct aactgcctct aatccttcca atacttggat ggacgagtca ttgtattcgt
    10501 tgtttacttt ttttgccaag gcaaacgctc cttcaataat actttgcggc aaaaccgcac
    10561 cacgattatc atactagaaa aggtcgtgaa aaaaaagagg gtagacgaga aatcaatttt
    10621 aattatctcc taaccgcttt ttcgacattc ccctctatcg atcatctctt ctttgtggtc
    10681 atttttattt ttggttttct ttcaacttac caagttcaat cttaatacaa cgatccatta
    10741 cgatatctgt acgtcctgct tttcttagca tctcagctgc ttctttgttt tcaatcccta
    10801 attgtgccca gaacacttta gcatcagttt tcaaaaaatc acctgctatt tcaggtaaaa
    10861 attcactccg tctaaataca tctacgatat cgattggatc atcgatttct gtcaaattcg
    10921 catagacttt ctcgcctaga atttcttcac cagccaataa tggatttact ggtatgattt
    10981 tatatccatt gtcttgcaat acctgtgcaa ccatgtaact tgttcgttct ggtttattgc
    11041 tcaagcctac gacggcaata ttttttgctt cttccaaata gttgaaaatc gtttcttgtg
    11101 ttggattttt tacagacatt tctgccaccc cttgcttttc tttttattcc atctattata
    11161 cttgtatctt tcattttttc aattgttcct gttacctatt catgctaaaa taaaggatag
    11221 ttttcaactt gaaagagggt aaaaaatgaa attgatctta ttacttattt tagcatatct
    11281 tttaggttct attccttccg gtgtctggat tggcaaattg tttttcaaaa aagatatccg
    11341 acaacacggg agcggtaata ctggaacgac caatacattt cgtgtattag gcaaaacagc
    11401 cgggattgtt gtcctgctta tggatatttt aaaaggtaca ttggctactt gtttgccgat
    11461 gatcttccac ctttctggga ttaaccctct ttggtttggg gtatgcgcca ttcttggcca
    11521 tacatttccg atttttgctg ggttcaaagg aggaaaagct gttgcgacaa gtgcaggaat
    11581 gcttttagga tttaatcctg tattttttgt ttattcttgt atcatcttta tcgttagttt
    11641 attttgtaca agtatggtga gtttgagcag tatgatcagt gcagtattga tcactttatc
    11701 tacgatcgtc cttccttatg tagctcctgt gattttggct aagcccaatt ggttactgac
    11761 gatcattgcc tttttagttt cttcctttat cttttatcgg cataaagaca atatcaagcg
    11821 tatcagaaac catactgaaa gtcgaatccc gtttggtttg aatagcagca agaaaaaatc
    11881 ctgatacttt ttcattccaa agagataaaa cgggagtgtg acaaatcgat gtcacactcc
    11941 cttattactt acaggatagc ttttttacac accttggtaa acggtgttcc ctgctaactt
    12001 ctcggtcaca acctcttact tcactgtgat ggaatatttt gtcttgaaga tttcatgggc
    12061 acctagttga ttgatcccta ctttttccat caagtttcca ctactgttca ccgtgtcagc
    12121 gattccgcac cacggttcga tacaaacgaa aggcgcttct tttggataag gagaccagat
    12181 ccctacataa ggcatatctt tatagcttaa agttacgcta tgggaagatt tttcacttcg
    12241 aatggcgtac gcatttagac cccttgtttc aaaaaccaag gcatcttgct caaaaagttc
    12301 acgattcaaa gccagattcg tatttgtctg acctaacgtc ttttgatcca tatcgatgaa
    12361 tgggcctttc aatggtaggc gtaatcttga tttcaatgga gaaaatgcca gatagaaatc
    12421 ttcaaatgac aatccttctt caagaggtac attgaaagca ggatgtccac cgatagaaaa
    12481 gaacatttct ttttcaccgg tatttgccac ttgataatga accgtgatgc cgtctcctcc
    12541 taattcatag ctgatcacta attcaaaatc aaatggatac ttttctaatg tctccggcgt
    12601 actccttaag atgaaactag ccatttcttg tccatgttca atgacttcaa aatccatatc
    12661 ccgagcaaat ccgtgttgcc ccatttgata tgttttccct tgataaacat actgatcatc
    12721 ttttaaacgt ccaacaaaag ggaataaaac cggtgcatgt ctgccccaat acgctggatc
    12781 accttgccag atatactcta aaccatgttc ttttgatttc agactgatca attccgcacc
    12841 gtgttcagcg atttcggcga tcagctggtc attttgaata ataacagtca ttgccattcc
    12901 tccaacttcg acttactttt taaaatggga aggctggaac aaacatttct atctgcccca
    12961 gtccccttac ttctaataac tgtgttttgc taactcgtct ttaaaacggg aattcaatac
    13021 ttttaaataa gttcccttca tgcctaacga acgagattca atgattccag ctgattccaa
    13081 ttttcgtaaa gcattgacga tcacagaacg agtgatgccg atactatcgg caatattaga
    13141 agcagtcaga cgaccttcat ctccatccaa tgcttcaaag atagcttgta cagccttcaa
    13201 ttcgctataa gataatgtgt tgattgccat ttggacagcc gttgcactcc gtacatctgc
    13261 ttcgatgctt cgagacttct gataaaggat ctgcataccg acaaccgtag ctccatattc
    13321 tgctaagact agatcgtcat ctgcaaacga ttgttccata cgagataaga taatcgtacc
    13381 caaacgttcg ccagctccaa agatcggaac gacagtcgtc agaccaaatg gatatttctc
    13441 tcttgactct accggaaatg cagtaatatc actagtaatt gggatattag cttcagtttt
    13501 catcaactgt gccactgtat cagtataaga ttcaggaaat tgtttctcaa caaacattgt
    13561 tttgattcgt tcattgttca catcgtgacg ttcattataa cctagtaata ctccgtcact
    13621 tcctatgata taggtgttgc tgtcaagaat accacctagt gtgacagcca ttttatcgta
    13681 aggcaaatct gcttgcatgt caaaagtatt cttttgctgc aaaagtgtgt ttatcttgcg
    13741 ggttttcgtt agcaagtctg tcattgtcgt cctccgattt tttataaaat atagcgactt
    13801 aaatcttcat ttgccgcaat tgagccaagt ttgtcatcca catatgcttc tgtgatcgtt
    13861 atttctccca tttgcatatc tggtgcttca aataatagat cttctagtag tttttccaaa
    13921 atggtatgca gtctgcgtgc gccgatatta tctgtgtcac ggttgacatc gaaagcgatt
    13981 tgagcgatcc gttcaattgc ttcttttgta aacgtaactg acacattttc tgtaccgatc
    14041 aacgcgacgt attgttttac taaagcatta tttggttcgg tcagaatctt cacaaaatct
    14101 tcagctgtca aatcatctaa ttctacccgt atcgggaagc gtccttgaag ttctggaatt
    14161 agatcacttg gtttagacaa atggaaagct cctgaagcaa tgaataggac gtgatctgtt
    14221 tggatgatcc cgtattttgt gtttacttgt gaaccttcga caattggcaa tatgtctctt
    14281 tggacgcctt ctctggatac ttctccagat tgctgtgatt tagaagtgat cttatcgatt
    14341 tcatcgataa aaataattcc actttcttcc gctaatttga ttgcctcact atggatatca
    14401 gcatccttga ctaattttgc tgattcttcc ttgatcaata actctaaagc ttctttgact
    14461 gttaccgtcc gttccacttt tttcttcggt gtcaaagcac ctagagtttc atttaggtcg
    14521 atccccattt gctccaatcc attgttcatc attggtgcag gtttcttttg gtcttcaact
    14581 tcaatggtta cttcacgact atccagtaaa cccttttgta gttgttccaa gactgtacgg
    14641 cgattgattc gaatatcttc tgtcacttct tcttgcggtt cagcggtatt ttgctgacta
    14701 gcattaaaaa gattcatcat ttgttcaaat tgattagtgg attgtttctg ttcttttttg
    14761 ataccaggta ccaagatttt taccaaacgt ttttctgcat tttttttagc acttgtgtat
    14821 acacggctgt actgctcttt ttctacgatt tggatcgcat tttctactaa atcccgaacc
    14881 attgattcta catctcttcc gacataaccg acttcagtaa attttgttgc ttcgactttg
    14941 acaaatggtg cattgacgat ttttgccaaa cgtcgtgcga tttctgtttt accgacccct
    15001 gtaggtccga tcatcagcat attttttggt gtaatatctt gttgcatttt ttcatctaac
    15061 tgcaaacggc gatagcggtt acgcaaagca acggcaacag atttttttgc tgcgtgctgt
    15121 cctacgatat attcatctaa ttcacttacg atttgtcttg gtgtttgttt taattcatac
    15181 atatctactc acctcttaca gttcttctac gataatatta tgattagtaa agatacagat
    15241 atctgcggca atatttaacg cattttctgc aatttctttc gcactcatgt cgttttgagc
    15301 atagtttttc attgctcggg ctgcagccaa cgcaaaattc cctcctgatc cgatagctaa
    15361 gataccatca tctggtgtga taacttctcc tgtacctgaa acaagaagca tttctttatc
    15421 attcattacg atcagcatcg cttcaagttt ttgcatagat tgctgtgtcc gccattcttg
    15481 agctaattcg acagctgcgc gttgtagatt cccgttatat tcgtttagtt tgccttcaaa
    15541 tttttcttct aaagtaaacg catctgcaac acttccggcg aaacctacaa caacttctcc
    15601 attgtagata cgtcgtactt tctttgcagt gcctttcatg acaacagatt cacccattgt
    15661 tacttggcca tctccagcca tagcaaattt cccgtctttt tcgacggcac agatagtggt
    15721 tgaatgaaat ggtgattcga ccatgtttgt ttcctcctaa atttgttctt ttccttattt
    15781 ttacgctctt ggatggaaag aacgatagtt tttttgtaaa ctttcttttg ttacatgggc
    15841 atagatctgg gtagtcgata aattggcatg tcctagcaat tcttggactg tccgcaaatc
    15901 tgccccatta tttaataaat gagtagcaaa tgtatggcgc agcatgtgag gatggatatc
    15961 actatccaaa ctgctttttt tgatcatttg attcaagaca tattcaattc cagtaggcgt
    16021 gattggtttt ccatgatgat tcacaaaaac gatatcatgc tcttcgtgat attttgtcat
    16081 caatacctgg cggccttccc tgaaatattc ttgcagagca tcttgagcaa aagaacctag
    16141 aggagcatat ctctctttgt tccctttacc atggatcaac atgacctctg aatcaaaatc
    16201 aatgtctgat accgacaaac tgctacactc acttaaacgg atgcctgacc cgtaaaggac
    16261 ttccagtaaa gcgcggttcc tcaaatccaa aggactatct cctgctacgc tgtcaaaaag
    16321 tgcttgcatt tcattttcat aaaaaaaacg tggcagtctc aaatttttct ttttgagatg
    16381 aacgtaagaa aatggatttt cttttatcac ttcttctttg agaagatact gataaaacga
    16441 acgtaggctg gctatcttgc gactgataga atttctgcta tagctaggac gatgatcagc
    16501 taatgcactc aaatagacac gaaccgtaaa atattccgcc ttcagcagat cagcgtctcc
    16561 agattcctcc aaaaaatgtt tgaaatggag aatgtcttct tcatatgctt ctttcgtttt
    16621 ttctgaatat cctctttcga caatcaaata acgcaaaaat ttttgttccc acgtggcttc
    16681 tgtcattttc tcaccttcct tttgtcccag agaataattt agcacagcgt ttataaaaag
    16741 acaaataaat tgtcagaatt taaccaatat ttctaagttt gttcacaatt ggcgcaattc
    16801 ctcacatttt gtttgagaaa ttcttaagaa aaacgcaaga aaaagagcga gactatccgt
    16861 ctcaccctct tcatggagtt tccttactca tttgggattg cagttttttc taattctgtt
    16921 tttattgcct cattagcttt taaagctcgt tgtgcaattg cttcatatct tgcttttttg
    16981 tctcgaatgc gctctggcag ttcaggaaac agaccatagt tggcattcat cggttggaaa
    17041 tgttttcctt ccgcatgagt aatgtagtaa gccatacttc caatagctgt ttcttgtgga
    17101 aactcgactg gttccatttc ttttgctaag cgtgcggcgt tgattccagc aagtagtccg
    17161 ctcgctgcac tttcaacata gccttctaca ccagtcatct gacctgcaaa gaacagatct
    17221 tcgcgtttcg ttgattggta agtcggtttc agcaattctg gcgaattcat aaagctgttt
    17281 cggtgcatca caccatagcg aacgaattca gcattttcta acccaggaat catccggaaa
    17341 acacgttttt gctcgcccca tttcaagtga gtctgaaagc ccacgatgtt gtataaagaa
    17401 gctgcagcat tgtcttgacg cagctggata acagcataag gacgtttgcc agttttagga
    17461 tcttccaatc caactggttt cataggtccg aaaagcatcg ttttgaatcc tcgctgtgcc
    17521 attacttcaa ttggcataca tccttcaaaa tatttttctt tctcaaaaga tttaagttct
    17581 gccacttcgg cattgattag tgcctcatgg aaagctttga attcctcttc tgtcatcgga
    17641 cagttcaagt aagctgcttc tcctttgtca tagcgggact tcaaatatac tttatccata
    17701 tcgatcgtag ctttgtctac gattggtgca gctgcatcat agaaataaaa accatctgaa
    17761 ccattgaatg ctttgatgct ttctgctaat ggatgagaag tcaaaggtcc tgttgctact
    17821 acggtgattc cttccggtat ttcagtaatt tcttcgttta tcactgttac taatggatgc
    17881 tctttgactt ttcgggtaat tgtttcagaa aaagaatcgc ggtcaacagc taaggcacca
    17941 ccagctggca ctgctgtttc atctgccgaa gtgattacta ccgaattcaa tcggcgcatt
    18001 tcttctttca ataaccctac tgcattagcc aaactgtttc ctcttaatga attggaacat
    18061 actagttcag caaaattact tgtgtgatgc gcctcagtcg atttgactgg acgcatttca
    18121 tataaacgga cagggactcc tgcttgtgcg atctgccaag cagcttcact tccggcaagc
    18181 cctgctccaa caacatttac cattttcaat gaaagaacct cttttctatt atttttggat
    18241 gtcttcttcg taatctccat ttacacagac tacttgttta ccgcctttga ctttcttctc
    18301 gaccagatat ccgtcacatt ttggacaatt tctgcccact ggtttatccc aagaagtgaa
    18361 ttcacattct gggaaacggg aacaaccata gaatagtctg tttttcttag attttcgttc
    18421 aatgacttgt ccttcatgac atactgggca agtcacaccg atttctttta cgattggttt
    18481 cgtattccga caatcaggaa aattactgca agcataaaac ttcccatatt tccctaattt
    18541 tatcaccatc ggatgtccac agacatcaca atcgaatcct gctggttcat ctttgatttg
    18601 aattttttcg attttttctt ccgcattcgt cagttctttt tcaaacggtt tatagaaacg
    18661 atcaaccact ttgacccacg cttccgtgcc ttcttcaatt ttatccaaat ctccttccat
    18721 ttctgctgtg aaatggatat cgacgatttg agggaagaat tcacagatta atgaattgac
    18781 aatttctcct agttcagtcg gctcaaatct tttttgtgtc aattttacat agtagcgtct
    18841 ttggatcgta tcaagtgttg gtgcataagt ggaaggtcgc cctaccccgt tttcttctag
    18901 tgcacgaatc aacgtagcct cactaaaacg tgctggtggt tgagtaaaat gttgttttgg
    18961 ttcaatatca acagattgga ctacatcgcc ttcttcaagt tctggaagaa tattttcttt
    19021 ctcttctttg ccgtcatctc taccttccac atacacttgc atgaatcctt tgaatttgat
    19081 ttttgaaccg ttcgcaatga agatgacacc attttgttct aatgtcactt tcattgtatc
    19141 taaaatagct ggtgtcatct gactagccac aaaacgtgac cagatcaatg tataaagttt
    19201 caattgatct ttatctaaat attgtttgag ttcatctggt gtacgaagca cactcgttgg
    19261 acgcacagct tcatgggcat cttgtgcgcc ttgagcattt ttgatctttc ggtgatcatg
    19321 tctagaaaat tcttttccat acgtatcttc aataaatgct gcggcctctg cttttgctgt
    19381 atcggcaatc cgggtagaat cagtacgcat gtatgtaatc aagccgactg ttccttgttt
    19441 acccaaagtg attccttcat ataattgctg tgctaccatc atggtttttc ttgttcgaaa
    19501 gtttaactta cgggcagctt cttgttgcag gctacttgta gtgaaaggat tcgcagggtt
    19561 tcttttgcgc tctttctttt ctactttttt aacttcgaag tctgttccat caattctagc
    19621 agtgacttct tttacacttt gtgcatctgg taatttcttt ttcttaccgt cgattcccca
    19681 gaaatttgct ttgaatttct tgcgagcttt tttaaaatta ccgtcgatgc tccaatattc
    19741 ttctggaaca aattctcgga tctctttttc acggtcaata ataattttta aagcgacaga
    19801 ttggacacgt cctgcactta accctttctt gaccttacgc cagagaatag gactgatcga
    19861 ataaccaacg attctgtcta aggtacgacg agcttgctgt gcatctacta aatctacatc
    19921 gatcgttctt ggttccttaa aagctgcttt gactgcgtct tttgtgattt cattgaagac
    19981 cacccgattt ttttctttca gatccaaccc aagtaggtac gctaaatgcc aagcaatcgc
    20041 ttctccttct ctatccgggt cacttgccaa gtaaactttt tgagcttttt ttgctgcggc
    20101 tttcaggctt ttgatgacat cgccttttcc gcgtatagaa atataatggg gttcataatt
    20161 gttttcaaaa tcgataccca ttttactttt cggtaaatct cttatatggc caacactggc
    20221 cattacttta tagtttcgtc caagatattt ctcaattgtc ttggcttttg caggtgattc
    20281 tacaatcact aaatatttat acgccattac tgaatggact cctttccatt gtcgtgttcc
    20341 tactattaaa agaggattca tacaaatcgt agctaatcat atccattcag aaaacgtttg
    20401 tcaagaaaag caaatgaaaa gtatggtgtt attctttaaa ttctgccaag atatcttcac
    20461 ccgaaaccgt gcaaactgca ccgtcttgga tcaaatgatg acatccggta gaatgttctg
    20521 ttaaaatatt tcctggaaca gaaaaaactg ttcttccaag atccaatgct tgctgtgctg
    20581 ttatcagaga gccgcttttt ttcttggctt caaagacaca tgttccttta gacaaagctg
    20641 cgataatccg atttctcatt ggaaaacaat gctttttcgg gccggattga ggaggatatt
    20701 cactcaaaag aagatgatca tttgcaatca cctcttgcaa gtcacgattt tcagcaggat
    20761 agacttgctc tatccctgtt ccaatgactg cgattgtccg tccaccatga gagattgctg
    20821 cttggtgacc gtatgtatct atccctttcg cgcagccact gacgatcaca tatccagctt
    20881 ctatcactgg ttttagtaaa taataaactg tttttttggc taaagcagaa gtgtgtcttc
    20941 caccaacaac gcttaacatg ttacaagaaa gtaaagatag atcaccatta taaaacagta
    21001 caattggcgg ataggtcaag tgaagcagct gagggggata tttgggatca aagcaagtga
    21061 taaacgactg tttcgattgg attttgcccc agttagcgtg aatttcctgc caacttttgc
    21121 gaaacagctc ccggtgtttg gttattttac ctatcttaat gatgtcttca aatccgattt
    21181 ctttataagg atactgcatc atccagttag caagtgccca ttttccttga ctactgattc
    21241 cttttgtata agcaagtttc aataaatttt cttctatttg atacatcata aaaccgcctt
    21301 tcgtctctct ttctaataag atacgtaaaa gcggctgttt tttattgtaa atattttttt
    21361 acaggtgcaa aacttttacg atggattggc gtaattcctt gtcgttcaag tccttctaag
    21421 tgttcctttg ttccataacc tgcattatgc gagaaaccat atccaggata aagcacgtca
    21481 tattctttca tcaattggtc tcgatatact ttagcaatga tacttgcagc agcaatcgac
    21541 acagatcgtg catccccttt gattattttt tcctgctgaa taggcaaatc caaggtcatc
    21601 gcatcgatca acaaatagct tggtacaatg gacaattttt ctactgcttg gatcatcgct
    21661 aatttacttg cttcataaat attcacatca tcgattgtct gctgatcaac gatcccgatc
    21721 ccgattgcca gggctttttc ttgaacttgt tgataaagaa gttctcgctt tttctctgat
    21781 aattgtttgg agtcattcag ccctaatatg atctcatttt tcggcaagat aactgcagct
    21841 gccacgacag gtccagctaa tggtcctctt cctacttcat caatgccggc aatccattgg
    21901 tgaccttgtg cgtacccttg cttttcaaag caaaacattt cttcatattt ttccttaatt
    21961 aatgcttcct ttttcaatcg tcgttcaaaa gaagccagtg cttgctgcac gcctttgcgt
    22021 ggatcatttc ttaatgattc tagtgtagga tcatctattc tctgtatgct tttcaatcgt
    22081 tctttgatac tttggatgga ttcagtcatc acttttttgc tccatttctt cgcaacgatc
    22141 cagtgtgtat cgtccaagtt ttccttgacg aatatcatgc acgactaatt cgctgccacg
    22201 atcatagtct tctttatacc cacgttttgc tgtaatatcc atcagtaatt ccggtgccaa
    22261 tttttcttct tgctcgattg ataaaccata acgatcgctg attcttcctg aataatatcg
    22321 ggcaaaaaag tctaatccgt aaatcgctaa atcatctaaa tggacaagct ggtctttgat
    22381 cgcgcctgtc agcgctagtt ttttgccgat ttcttcatct tcaaatttgg gccataaaat
    22441 ccctggtgtg tctaacaatt ccaactcatt acctaaacga agccactgct gaccttttgt
    22501 tacgccaggc ttatttcctg tctgtgcaat tttcttgcct actagtcgat tcatcaacgt
    22561 agatttccca acatttggaa tacctaagac cattgcccga atagcgcgag gcttgatccc
    22621 ccgagcagca tctcttgccc gtttttcttt caatgcttct ttagccgcag gtactagacc
    22681 tttaattcct ttactttctt gtgccgtgat agctaatgca agatggcctt gtttacgaaa
    22741 atattcttgc cacagctttg tctgttgtgg atctgccaga tccgctttat tcaataaaac
    22801 aaggcgaggt ttttgctgaa tgatctgatc tagcattgga ttacgagaag ataaaggtaa
    22861 tcgtgcgtct accaattcaa atacgatgtc cacatatttc attttttcag aaacttctcg
    22921 tcgggctttt gccatatgtc ccggaaacca ttggatggtc attgttctct ccattccttt
    22981 cataccggaa tattccccgg ctttacttgt ttttttcttt ttcaatataa attcactttt
    23041 ttattataaa gaaattccat ctattagtta agtgaaagtg aaccagtcct cattctatca
    23101 catcttcact tttttgatga tgcaaatttt tattttggtt tctatatatg aatctaaatt
    23161 tttgacagcg tttcctaaat aagagatgat agacgaacaa aacagaaagg agacgaaaca
    23221 aatgaatagt atggtttttg ttaattttcc tgttgctgat gtcaatcgtt ccgttgcttt
    23281 ttatgaaaag ctgggtttta aaaaaaatga agaattttct actgaagaag ctggttcaat
    23341 ggtatgggat gacacttttt ggataatgct tctctctcat gatttttata aaaaatttat
    23401 aaaagataaa gaaatagctg ataataaaaa aacaagtggt gctttgattt cgtttagtgt
    23461 tgaaaatgcg gatgaagtaa aaaaatttgc tcaaattgca aaagaaaatg gtggtacttt
    23521 ccacgaagta gatatgggaa tgcctgaaga agaaatgttt tcattagaag tccaagatct
    23581 agacggaaat acattagaac ccgtatggat gaagatgtaa gcagataact aatctgacgt
    23641 tttttataac aaaaaaacaa aggcggatga tacgataagt attctccgcc tctatttttt
    23701 ttattcgtac aatctctttt ttacagttta taaaagcagt cttctcaccc tttttttaat
    23761 tgttagatgc cagtgtatgt aaatcaccaa tgtgtcatga cacattggtg attttatggt
    23821 atccttttat tattaactga caaaggagag aatattttga acactttgat tgcaaaagac
    23881 gtttttagat tgcccgaaat gaatgcaaga ttgttgtcga cctctgctct tttattagcc
    23941 cttgatgtca tcttatacaa gatagcgatt ggtcctgctt attttcaaat cacattcgga
    24001 tttttaagta tggcgcttat gggttatcta tatggaccga tctgggctgg tttgcttgaa
    24061 atgttgtcga acactttaaa tttcacgata tttggttcag gaacgtttca agctgctttt
    24121 cttatcacgg ctttccttgg tggatttatt aatggcttat ttttatatca taaaaagata
    24181 aacctgcctt ccgtcatcgc tgcccaatta ttgattatga tcccagtcag cctttttatc
    24241 aattcttggc tgatgtctgt tttgtttggt gcagatttca aagtaatttt tctaggtaga
    24301 ttcatcagga atatgatcca aatccctatt caaataatgg ttgtttattc atttatcaaa
    24361 actttagagg ctagaaaagt gtttaaacga gctgtttgat tttacgtact aaggtagtaa
    24421 actgattttg gattaaacaa taaagcgtgc agtctcaaca gactgcacgc tttattgttt
    24481 ctcactggat ccattttatt tcatcaagtg gataatagac aaatcttgct ttacctagaa
    24541 tatcagtttt attgatcgtg ccaaacgaac gactatcttt tgaaactctt cgattatctc
    24601 caagtacaaa ataattatct tccggaagct tggattgtcc cgttagctct tgtagtgtaa
    24661 agtccgtcgt ataggatgca tttgcatgat ctgatttcag gtttttagtt agataaggtt
    24721 ccttaactac tttcccattg atcttcaatt gatcattttg gtagctgaca ttttctcctg
    24781 gaagaccgat tactcgtttg atataaatcg tgccatctgc taattgaaaa acaacaatat
    24841 caaatcgtct gatctccgaa aatttttcca tcacaaccat atcaccttgc ttcaacacgt
    24901 tttccattga attgccttcc actggtaccg ggatgaataa aaatccccgc aacatgaacg
    24961 caaggaatac agaaacaagt aagtatttga atacaagcca gaagcgatta atatagcgtt
    25021 gtttttttgt caatctctat caatccatcc ctcttttttt cattctttct ttattataag
    25081 aaaaatatca aaaaaatgcg actagatagc tgaaataaaa ataattcttt caattaggct
    25141 attggacaaa aaactttttt gatcataaag tacaaaacta tctcttatat gtcatgatta
    25201 ttttctaaat atttttccca tgcttcgtca aagatatcca tggacggcaa atagtcgaca
    25261 ttcagttcca gataattaga aatttcttcg tagctagagc tgtgcttagg aaattggatg
    25321 tctttaccgg cttctgtagc gaaaacagat aaagcatcat gtgtgccacc gcctcgcagt
    25381 gtcattaaat aatgaaaaaa gcttcgattc acccttcgtt cctccaattt tcttcgataa
    25441 aggcagcccg gcgtgcatgg tttcttttaa aattttcagg atgcttttta taatactctt
    25501 gatggtcttc ttctgctaga taaaatggtt gggctggttc gatttttgta acgattggct
    25561 gttcgaaacg tccactttca gctaactgtt tcttactttt ttcagcaatg atccgctgtt
    25621 cttctgtcaa ataaaagatc accgggcgat aattgtcacc gcgatcctcg aattgtccga
    25681 aagcgtcagt tggatcagtt tgctgccagt aaagttctac taattgttca tatgaaatca
    25741 atgttggatc atagataatc tccactgctt ctgtatgtcc agtcgtttgg ctttttactt
    25801 gttcataagt cggatctggt acatgccctc cagtatatcc tgacatcact gtatggatac
    25861 caggaagcgt gtcgaaaggc tggatcatac accagaagca gcctcctgca aatattgctc
    25921 gttccattat gattccccct ctaatactac tcatccgatg attttttatt ttcttttgtc
    25981 ttgctttcag tactgctggt gctagttttg ttggtatttg agttgtttga agcatcagag
    26041 gtatcttttg gcaaatatag actaaaccga atgtcatcat ttactaagtc gattttatct
    26101 gctttaatat acatcccgtt ttgcattcgg aattgatcca acctaagcat gatagtcaga
    26161 tcatctgtat tgacttcgat ccaatctggt aatttatagt ttctcttgat catattcatc
    26221 acatctttga ttggcaaact caatgttccg atagaaagac ttctagcttt tagttggaca
    26281 tttccgtttt ccatcacata cggatcaaaa tataaataga aatcgatagg aaaacctagt
    26341 acttcgaaag taccattgag tagtgcttca ttttccaaat aaaatttata ttcaatatca
    26401 ctatcttttt gatactcact aaggaaaaag ctgatgattt gattgacttt ttctttattt
    26461 gaattgatcg ttaagacagg atctccttgt ctttccgtaa gagctggtat ttctgggagt
    26521 tctggttccc gattagcaaa aatacggctg cctaaaaata cggtcgaacc aagtactacc
    26581 ccaagaagga taaggaaggc gaatttccag taatttgttt tctttgtttt gtttgaagat
    26641 acgtcagatc ttgttttcat gtttattgat catcctcctt ctctaaccat tggttttgtg
    26701 tctcgatcag ctgatctctc actgcatttg ccatcaattg ataacctaaa ttatttggat
    26761 ggaaatgatc ttcttcatag agcacattat ttttgatgcc atttagattt tctgtcgtgc
    26821 tagttgtttg atctgttcct tcttctgtga cacctacttc ctgattcaat ccttgataaa
    26881 gcaaatcatt gattgggata aagtagcagt tcggcatttt ttttgtcacc gtttctgttc
    26941 ctttgttcca attgttaaca attgtctgca tgtcagtgat ctcaggaaag ttcaaataaa
    27001 atggattgta gatgcctaaa atgtaaatag gtgcggtttt attgagggat cgaaattctt
    27061 ccaatagttc tgtgacattt tcctgatagt ttttcagtgg ctttttaaag gaattgaccg
    27121 ttaacccgaa taaattattt tggataactt tcatcaaatc attaccgcca acagtcagtg
    27181 tgataaaatc agctgttttg atattgtttc gaatttcttc ttttgttttt actcgcttta
    27241 agatctggtc acttcgttca ccatttacac catagttttc tgtttcaacc gcggtcaaat
    27301 tataacggtc ttttagatca tttgcgacaa ggggaacgaa tcctccttgc ttggtttgat
    27361 ctcctactcc ttcagtcagc gaatctccga tagctatgta gtgaagtttt tcttttttat
    27421 ttggatcttc tctcacagta gttactggtt tcattagtgg gccagctttc ggtatagaag
    27481 cagctaaacc tgcatagatg atgatcgcaa ttaataatgg gaacaaaacg aggatcaaat
    27541 gtcgtttcgt taatttcatt ttttcacctc ttgtattcga ttggttctaa tgttatcaaa
    27601 aattttatca aaaaggtagt ctttatgaaa aaagaaaaca attattttcc taattttata
    27661 aagaaaaaga gaataagctg caagcctttc aggctgaggg cttatcctct tttcgactaa
    27721 tctacataat acatgattgc aaacgcgtct ttaccagtat gcgtagcgat aaccggattc
    27781 gtatgcagta cagggatatg catgtccggg aataattctt gcaaaccctc tttgaattct
    27841 tgcgccaatt cttttgcatc cgcatgtgaa ataccgattt gtcgcacatt tggcaattct
    27901 ttcagttcat ttttcaaatt attaaaccat ttatcgaacg ttttctttcc tcgcccctta
    27961 gttacaggga ttaattcaga atgggcgaaa ttcatcacca cgcgtatgtt caaaacacta
    28021 gacagcaaac cagttgttcg gctgattctt ccacctttta ccaagttatc tagtgtggat
    28081 attccgatgt ataattttgt attgtcttgt acttttttga cttcttcaag gattttctct
    28141 actgttttac cttcttttgc taattcagct gctcgaatta cctgaaaaga taatccttgg
    28201 tcagtggtat cactgtcgat aaccgttact ttcgtttttg ttagattact ggcttgtctt
    28261 gctgcttcta ctgttccact caagcctttt gtcatatgga tcgaaatcac ttcactgccg
    28321 tcttctccta gctcatcata catcgagatg aattctccaa ttggtggttg gcttgttttg
    28381 ggcagatttt ttgctttcgc catcatttcc ataaatcttt cgccgtctag ttggtcatca
    28441 tcgggatata ctgttccgtc gatcatgatg gatagcggca tgacacgaat gcctaaagca
    28501 tcgcgtacat ttttttccat cgtacatgaa gaatctgtta cgatttttac atttgtcatt
    28561 attttctctc tctctttctt taacaagatg ccttattcat gttaaactac atgtaagaca
    28621 atttctattt ttagtataac agacaaataa tgatttttca ttaattacac ctagtaaagg
    28681 agccgttttc atggaaaaaa cgaaatttaa tcgaacgtat gaaatattaa atgaagtgtt
    28741 taatgcagtc acccatggaa ttgggactgg attgagtatc gcgggactag tggttctttt
    28801 agtaaaaggt gcccacttgc attcctccct ccatattgtc tcttatgcta tctatggatc
    28861 gatgatgatt cttttatttt taacgtctac tttgtttcat tcattgattt ttacaaaagc
    28921 aaaaaaggtg ttccaagtat tcgatcatag ttcgattttt cttttgattg caggaagtta
    28981 tactcctttt tgtttgctga gtatccgagg atggctaggt tggactttat ttgtattaat
    29041 ctggttgttt gcgattcttg gcattatata taaagcgttg acgttgcata aacgggagag
    29101 agtatcaaaa gtatctacga tcatctatat ttttatgggg tggctctgtg tcgtggctgc
    29161 tgttcctctt tatcactctc ttggaatgac tggtgttatt ttgatggtag caggcgggct
    29221 ttcttacacg ataggcgcat tcttttatag cttgaattct atccgctata tgcatgttgt
    29281 ttggcatttg tttgttatgt taggtgcagg ttttatgtac ttctctgttt tattctttac
    29341 ttaataaaaa aaataaagct atggatggga cagctctaaa taacagctag tctatccata
    29401 gcttttttat atcgtcaatt cgcctgtccc gctttttaca ggattctcat tacgctgata
    29461 cgtttcaaat tgatgcggat aacgattttt ttcatccatt tctccttgac tagtattgat
    29521 cagtgaccaa tcagaccagt caacaggtgg aaaataagca tctccatcga atacatgatg
    29581 gatgactgta cggtataata tcgtacaaaa tggcagaaat tcttgataaa cagctgaccc
    29641 tccagcgatg aaaaagatac cgtctgtttc tttttccaga gcaagcacgt cttccacact
    29701 atgcatgaca tgcacgcctt ctgctttata ggaagaatct ctcgtcaaaa caatcgtctg
    29761 acgattcggc aacggacggc tacccatccc ttcgaatgtt tttcgtccca tcactagtgt
    29821 atttgcttct gtcatttgtt tgaagaattt cagatcattt ggcaaacgcc aaggaagacg
    29881 gtcttctttt ccaatcaatc cgttttcatc ctgtgcccaa attgcagcta acattttctc
    29941 atcctttctg attctaaaca gcgataggag ctttgatcgc cggatgtggg tcatatcctt
    30001 ctaattggat atcttccatc tcaaaatcaa atactgactg cttttcctga ttcaaaacta
    30061 aagtcggaaa tgcgcgtatt tctcggctca attgttcttt catttgttcg atatgattga
    30121 tataaagatg agcatctcct aatgtgtgaa caaattcgcc aaccgctaaa cctgtttcat
    30181 gtgcaattag gtgagtcagc aacgcataac ttgcaatgtt gaacggaacg cctagaaaca
    30241 catccccact gcgttgatac aattggcagc ttagccgtcc ctcttgaaca taaaattgaa
    30301 acatcgtatg acaaggaggc aaagccatgc taggaacatc ttccggattc catgcagaaa
    30361 cgatcaatct tctagaatca ggagtctttt tgattgcttc gatcacttgt ttgatttgat
    30421 cgataaagcc accgtctttt gtttcccagt gacgccattg atagccgtag atgtgtccaa
    30481 gatcgccgta tgtttcagca aaggaatcat cggttaggat cttctcgcaa aaaagcttgc
    30541 tctgcttttt atattcttca ttgaattcag gatctgtcaa acatctatgg ccaaaatcag
    30601 tcatatctgg tccattatag tctggacttt tgatgtagcg ttcaaatgcc cattcatccc
    30661 aaatatggtt tttattttgt aatagatagc ggatattcgt atctcctttt aaaaaccaaa
    30721 gcaattcgct tttgatcaat ccaaaaggta ctcgtttcgt tgttaacaaa ggaaaccctt
    30781 tttgcagatc aaaccgcatt tggtatccga ataagcttaa tgtgcctgtg cctgttctgt
    30841 cttctttacg atgcccttct tccaacaatt ttcttcctaa gtcaagatac gcttgttcca
    30901 tcctttttcc tcctaatctt ctacccattc actcaagtat tcccaccgtg ccattttttc
    30961 ttcaagttgt gcttctgttt cagatacgtc gttttgcaat tcttgtaatc gagtgaaatt
    31021 atctccttga tgattcatct cttcttggag caatgagatt ttttcttcaa gttctgcaat
    31081 ctcatcttca atcgtttccc attctttttg ttccatgtaa gataatttct tcttttcagc
    31141 aggttccttg ctctgtattt ttggtttcgc tttttcagca ggctgctggg tctctttttg
    31201 cttcagtaaa taactggaca tgtttccgta ataaagttct tgttttccgt ttccttggaa
    31261 tactaataac ttatctgcta ccttgtccaa gaaataacgg tcatgggaaa cagtgatcac
    31321 agcacctgga aaacttctaa aataatcttc caaaatcgtc aatgttgcta tgtccaaatc
    31381 attggtcggt tcatccaata ataaaacatt aggttgctga atcagcagtt tcaacaaaaa
    31441 taaccggcgt ttttctccgc ctgaaagttt gcctatcagt gtcccatgca taaatcttgg
    31501 aaataaaaat cgttcaagta attctgctac tccgatttga ctgccatctg ctgtttttgc
    31561 ttcttcagca gcttcttgta agtaagcaat catccgttta tctggtgcca tttcttcatt
    31621 ttcttgtgta taatacgcaa gatgaaccgt ttcaccgata gacattgtac cgctatccag
    31681 gggaattctg ccagctagaa tattaagcaa tgtcgatttt cccgcaccat ttttaccagt
    31741 aatacctagt ctttcccgag attgaatcaa taaatctaaa tgttctagca gtgtttggtc
    31801 atttatacgg taactgccat ctttgatttc cagtactttt ttccctaaac gttgtgtcgc
    31861 taggttcagc tctaaatcat cttcttggtt tacttggtac aagttctcct ttagatcttc
    31921 gaaacggttg atccgtgctt gctgcttggt gccacgtgcc tgtacgccag ccctcatcca
    31981 agctaattcc tgtttataaa gccgcttgcg cttttcttct tgttctactt ctacacgatc
    32041 acgttctgct ttttctaaga cgtaagcttc ataatttcct ttatactcgt ataattttcc
    32101 aaatgaaagt tcgaagattc ggtttgctac tctatctaga aaataacgat cgtgggtaac
    32161 catcaatagt gcgccacggt attgtttcaa atagttttcc aaccactcga tcgcttcata
    32221 atctaaatgg tttgttggtt cgtctagtaa tagtaaatcg ggttcatcaa tcaacacttg
    32281 cgccagacta actcgttttt tctgaccacc tgataaagta ctgatttttt tatctaattc
    32341 actgattcct aatttttgca aaataatctt tgcgttggta tctgtagtcc aagcatcttc
    32401 tttattcatt tgttcttctg ctttagcata acgtttttgc acatcagggt cttctccgtt
    32461 ttcccctagt tcgatcaatg cttcctcata tgctcgaaca gtttggatca aggggctgtt
    32521 tccttgaaag actgcttgga gaacagttaa ttcatcggaa aattcagctg cttgagaaag
    32581 ataaccaata cggtaatcag ttggataaaa cactgtttgc cgatcaccgt cgctgctatc
    32641 gataccggca ataatattta agagacttgt tttacccgtc ccgttcgtcc caatcaaccc
    32701 gatacggtct ttttcgtgga ccaaaaaaga aatctggtca aacaaatctt tttcaccata
    32761 agtttttttg aggtcagtta cttttaattc tttcaacatg ttccctcctt atcttggata
    32821 ttgtatcata aaaatagtga acttcaggaa aatttttttg gtatttgttc tttttgtgtt
    32881 ctcaaaaaaa gaacaggacc gattcgatcc tgttctgata tgttttgttt tttataaaac
    32941 ttgaaaattt ttaccttttt attttattgg actcgttttt tttgactttg ctcgaaacgc
    33001 aaatcggaaa gaaaagttat cagatggttt gttcatcgta taagattcta acaaattgat
    33061 attcctgcga tagctgttcg cagaaaacgt cgtgattttt tcagcaactt cgtattcatc
    33121 aatgattttt ctttcaagat aataacctct tagcattttt ttcgtaaaca gactatcttg
    33181 ctggatcatc cacgaagaaa tcaaattccc cgagttcatt tttattcctt caagtttgcg
    33241 ttgctggata aaaaattgaa ccatcgtttc atcataaata tcagtcaagt tatctaaact
    33301 ttcaataatc aactgagtat ttttttgata tgtctctctg atttcttgga tatcttcatc
    33361 actaataaat gtctgacgat cagcatatct tctttgccaa aacattttcg gatggagaac
    33421 gattcgcatt aacctacgga caacaatgaa ccaaaagccg ataaaagaca aaatctggct
    33481 tgtgatagaa tgttcgaatc gagaaagaaa acgggagtaa aaacgataac cattagaaga
    33541 aagcttgccc gaacgataac tttcatccaa tccatcccgt tcgatcgaca aaatcagtgc
    33601 ttgtatttct tgtacttctt gcttttcatc atcggttaaa tcttccaagt acagatcacg
    33661 tatccgttct tgataatttt ctatcactgc ttcagtggct aaaaattctt ttgtattacg
    33721 atcaatttcc tttatttctt ttcgcaaaac ttcaacgacc tcttctaaaa tcatcaaagc
    33781 attcaaatcc gtgcttttcg cttcctctgt ttccgtcagc ataggcaaga caatgatccc
    33841 tatgaccaaa gtcactaaga tgacacccgc cgtcagaaac aaaagcaaag accgctggta
    33901 aaacatcata ttattgattg aaaatggcaa aataaaaatc gtagccaaac tgactgttcc
    33961 ctttacaccg ccaaatgtta agatcaagat ctcgttcaac tgttttttga actttttact
    34021 gccatctttg aatacataaa aaagactgat agaaatgaat ctgatcacaa aaagcatgac
    34081 agagattaat acgataatcg ctaataaaag accgtttgga tataaaccgt ctccccatac
    34141 tggcgagaac acttgcgtca attcgattcc taaaaatata aatactaatg cattcagtgt
    34201 aaaagcaata gttgtccatg tactgtggga caagctcgac aattctgcat caaacacaga
    34261 gattttccta aaaccagaag cttggagaat acctgctgcc actgcagcaa tgattccaga
    34321 tacatcaaat gcctctgcca atacataggc tagaaaagga agcaaaagtt cgatcagcag
    34381 ataccctgtg acatcttgtg ctgatgcttt ttcgatcaaa tgaattattt tttgtttgaa
    34441 ccagacaagc aaaaagccga tcaaagctcc cccaatacta gaaactacta gactcatccc
    34501 cgcgtttact gctgaaaaag atccggtgat cagcgcacca agagcaaact ggaaggcagt
    34561 aacaccagat gcatcattca aaagaccttc tccttccaaa atatgcatcg cctttttagg
    34621 gatattcact cgtccagaaa gagaactgac tgctaccgca tctgtcggac ctaacgctgc
    34681 tccaaaagca aagcaggcag caagtgggac acttggcaac aggaatgata acgtcgcacc
    34741 taccccgaca agggtcaaaa tgactcctcc aaatgccaag aacaaaattg tcccgaaatt
    34801 tttgagaatc gaagaaatat ctgctttttc tccttctcta aataacaatg gtgcaataat
    34861 cataactaag aacaattcag gttcaaaatc gattgattgt ccccactctg tcagacctaa
    34921 taccactcca aggaaaattt ggatcagtgg agctggaatc attggcaaaa tgcggctagc
    34981 tatgttcgat aaggtgatcg ttactgcaaa tacaataact aactcagcaa attccatcgt
    35041 ccatcccctt tattttttat tttgtgtaag catttttaaa aattgttctt ttttctttaa
    35101 aattttggtt tcgactactt caacctgtgt ttggttcccc tctaattcac actgtacacg
    35161 ttttgactcc aaacgaagca gatcatgttt cagacgttcc aactgacgat acatcaatat
    35221 atttctttta cgcaacttac aaagtatttg acggcggtca tccatcgaaa gggcgccata
    35281 gcgatcatgc aacagttttt tttgttgttc aaaactctct ctcattttcc agatctccta
    35341 tacacaaact tccatcatta tagcaaagtt ctttttggat gaaaaatatt tcattgtttc
    35401 atcgtttatt gctagttaga aatttccata aatttttcaa cgcctcattc tattccaaat
    35461 agtatcagat atcaagtaaa acttaagaaa gataaaagtt tctgacaaaa ggatgtttac
    35521 tttcccattc ctgcctttct tgttctttta tcacaacaaa aaaatggggc tgcgacaaaa
    35581 atcttgtcac agtcccttat tctgaataaa cggtgtggaa gagacagcct atcagtagta
    35641 ataagacaca tctctttcac agcctcattt ttgcgtaaaa atcgatttat tcgaaaaatt
    35701 ccccgtatac atcttctaca cgttgatctg gattgatcac gatatacaag ttacctgttt
    35761 tttcgctgat ttttgttgat tgatattgat tgtctaatcc ttctgttcct ttatctagat
    35821 atgggaagta cacaagatca ggtgtgccat ttcggtaaag gatttccatt cgctcgatat
    35881 cttcgtattt caatgcgcga ttaaacatgc ccatttccag tccgcctagg ttgatatcat
    35941 gtgtcgcaac tgcgtcccct tcatggaaga tttcgatttt aaatccagca cacggatgga
    36001 tttcaacaaa ttcactgcca ttgattcgtc caaaacttgt tgtgatttgt ttgatccaaa
    36061 gatcgccgat atgacggcgg ttgatcgtcc aggtttctcc atttctaaaa taaaatttta
    36121 gcgctgtcat ttctttactc attaaaaaga ctcctttatg atgtaattta ttcttgtact
    36181 acctcagttt agcacaaatt tatgtaagtg gtcacatctt atgttttttc ttctaatgac
    36241 gtatctgccc actttaagta gccaacaaag ctgagcagat acagtctagt gttttttaaa
    36301 tcaatttttc tttcgataaa aaatccaaaa cctgtttttt atcatttttt attctttgtt
    36361 ctacgacggc tttttcagct aattgcaaag cttcactaac ccacttacca ggtttttttc
    36421 cagtttcttc tagcaagatt ttaccatcta ctgctaattc gcttaatgac ttgataggta
    36481 aacgatcata ggattctcct acggcatcca tctgaggtgt ttcgtcaaaa tagatcatca
    36541 attcttctac ttgcagtgca tgttttttgc ctaagaagta caattcgaat ggttccaaag
    36601 ctccagtttc tcgttgtcgt agtccttgga caagtgcttg aacgtcttta atcatttggt
    36661 tagaacactt ccacgatttc aaaaaggaac gaatctcatt ttcttttaga tccagttggc
    36721 tgatcaataa tgcccatgct tggctctctt ctttcaatgg gacggatggt aattcagcaa
    36781 aacgtaaaag tgcttcgcct tcttctttca aaccgggaca gcaaatgtag cactctgttt
    36841 caataaatgc atggattccc gcggcccgtt catttcccaa gagcatcttg atgaattcca
    36901 catttatacg ttctacagat attttaccta atagctcgtg gttttctttg atggcgtaga
    36961 aggtttcttc ctctaatttg aaccctagtt gactgacaaa acgcaacccg cgcatcattc
    37021 gtaaggcatc ttcatggaac cgctcatgag gattgcctac agctcgcaag atctgttctt
    37081 ctagatcttg cagaccatcg aacaaatcga tgatttctcc atcttctttc aaagcaaacg
    37141 cattgatcgt aaaatctctt cttttcaaat cttctgccaa cgaacgaacg aattcgacat
    37201 gatctggtct acggtagtcc tgataagttg attccgtccg aaatgtggtg atctcatatt
    37261 gttcatcatt ttctaatacc aacacagttc catgttcgat cccaatatct atcgtttttg
    37321 gaaaaagctg tttgatttct tctggaaatg cgcttgttgc gatatccaca tcatggattg
    37381 gctggttcag caagatatca cgaacacttc cacctacaaa ataagcttca tatcctgcat
    37441 tctctaattt tttcagaact ggaattgcct tttggtattc cagaggtaat tgttttaatt
    37501 tcatttttcc aacctttcct gcgtgtttct tgtcctgaga taaagactca gttgcatggt
    37561 gactgtttga caagtccgtt tcagagtctt caaggccagg accacttcat cttgtttact
    37621 cgtccttacg ctcaaagcga ttatggtctc tttgattgaa tttttccatg tttttttcaa
    37681 aaacttcagt taagtcgata ttcaatgaat tagccatgat catcgtaacg aataaaacat
    37741 caccaagttc ttctgctacc gagttaactg gttcagaagc ctttttgctt ttttctccat
    37801 aagtgtggtt gacttctctt gccaattcac ctacttcttc agttaatcga gccatctgag
    37861 ctaatggaga gaaatacccc accttgaatt gctggatata ttcatccact tcctgctgca
    37921 tactgtataa agaacgcttt ttatccatct ttttccctcc aaaactatct taccaaaact
    37981 ttaacgcaaa tcctagataa gagcaattga gaaaatcgaa tttccatgct acatttagga
    38041 aggaatttct aaatggaaat tctgtgaaaa tacataattg aaagctggaa ttcatatggt
    38101 caaacgaaaa acagtaaaag aagttctttt tatcattata ggaacaagta tttatgcatt
    38161 tggtcttgtt tacttgaaca tcgctaatca tttagcagaa gggggagtct cagggatcac
    38221 cttgatctta agagctttat ttggtattga tccagcttat acgactttat taatcaacat
    38281 cccattgatt ttactaggag gaaagatcct cggtaaacgt tccttggcct atactgttct
    38341 aggtacactt tctttgtcat tctttttatg gatctggcaa agggttccac tagaaatcaa
    38401 tttacagcat gatctactga tcgtttctct acttgcgggt ttagttgcag gtgtaggaag
    38461 cgggatcgtc taccgcatgg gtggaacaac aggcggcagt gatattatcg ctcggatttt
    38521 agaacaaaat tacggcatca ctatggggcg ttccctattg gcatttgata tcatcgtctt
    38581 acttgcttca ttaacctata tcgacttgaa acgtatgatg tatacgttga ttgtttcgta
    38641 tgttttcagt cgtgtgattg attcgatctt agatggcgga tattctgcaa aaggtctact
    38701 tgtcgtctcc aacaaaagcg aagagattgc accactactg atgaccggtc tgcaaagagg
    38761 tgtgactttc ctttctggag aaggcgcatt ctctggtaat tcaaaaaaaa tcatctatat
    38821 ggtcgttagc tctagtgaat taactgaagc taagaggatc gtccacgaga ttgacgaaaa
    38881 agctttcctt tcaatcatca atgtgcatga agtggaaggg caaggcttta cttatttgaa
    38941 gccacagaca agattactga aaaaactata agaaaaaaga caaagatagg ctatgaggaa
    39001 agattccaca tccagctgac ctttgtcttt tttagtacta tactattttt aactaattgt
    39061 tatgttcact tacccggtta cttttctttt gtgtctgcaa aaggatcttt cggttaactt
    39121 catcagataa tttcaaaaaa gcatccctat ctccatcttc tagtgcttga tcgatttgag
    39181 cataaagcat ttttagtttt gcctcttctt ctttttcttg aaaatatcgt tcaattaatt
    39241 cagtatcttc ttcactgact gaagaatccc aagaagaaaa tggattgtct tctaagatag
    39301 atagatattc tcttgtctgc caagcatttt cgaatataca ttccacatat aaaggctttt
    39361 tccaattcaa acggatttca tgaaaaatct ggtctgtgtc cgtaaattct tttccctgca
    39421 aaaacaattt catgggttcc ccttcaacag atagatcact gatctgcagt cctcgatccg
    39481 caaaattcgc cccttcaaca aagtggacat tgcttaaaat cgcttcatga ttggcaagat
    39541 aattcaagat ccaaaaaact tctcttcggc taaaagatac atgattgacc atccacgtta
    39601 aaaaattctt cttttcccgt acatcaatta gcatttttct cacctctctg ttaggtcatc
    39661 taataatgac agtgcctcca tatctcctgg ttcaagtgtt aaataataag tcaataattc
    39721 ttgcgctctt ttcagctgcc cttcttctct taagaaaaag gcatactctt tcaagaaatc
    39781 tggttcatgt gatagttcat gataagcctg ttcatagtgt acagctgcaa cggtaaagtc
    39841 ttctaattca ttataagcat gggctaggtt ccattctgca taaggattag cagtttcttc
    39901 catctgattg atcacttgta tcacatcttc atatctttca tcatccaagt aaagattact
    39961 taaagtaagt aatgtttcat cttgtttgtc tcctacttct aaagctttca gtaaaagttc
    40021 ttctgctcgc tgtctatcat gcagacggaa agcattttcc gaggccaggt gataaagttc
    40081 gacttggtaa ggattttctt tgattccttc ttctaacact gtttgtgctt cttcaatcat
    40141 ttcttcttct tgaagagctt gtcctagata tagatataac gattgataat gcggattaac
    40201 ttctcgaagt tcttccagat agttgattgc ctgctgattt tctttcaatt gaagattcgt
    40261 aaaagctagc tggaacagtc gatcatctgt cctttcttct ttcagtgctt cttctaaagg
    40321 tacgatagct gcttcgaatt ctccttgcat acttaaggat tgtcctaaac gttcctgcat
    40381 cgagattcct gaaatttcat ttatcccgct tgccaacaat gtttcataaa ccactgctgc
    40441 ctctttgaaa cgatcaactg aaaaatacaa ttcagctagc gcaaactgga tcaatggttc
    40501 atcaggaagc aacccagctg cttctttcaa ttttgcttca ctcacttcag ggattccgat
    40561 aacttggtac aaatcagcta tcgccaataa gctttgcgga tagtaatcac tttgcttatc
    40621 cactttttcc aggtattcaa aagctaagtc gatctcatta tcttcgattg caatttctgc
    40681 taacgggatg ttcagtccgt cattttctgg gtattggttg atcagttgtt caaaaatctg
    40741 ttttgcttcg atcaaaaagc caatagccag caattcttcg cctagttcag ctaatatatc
    40801 tgctgggtct tcttttaatg ctttttctaa aaagatttgt gcttgtgaca agtcttcatc
    40861 tgataaagct tgcaacattt tttcgctatt tgtattcatt tcaattccct cttatctcac
    40921 tgacgatttg ttgaaatacc gtcattgttc tcaataattc tttttcgttt ggatgttggt
    40981 atccgtctat tatacctatt ttttctaaaa caagtatttt tttgcttttt tctgccaaaa
    41041 aaagaacttt ttccaaatac tccatctttg aaatctgttc cagccagtgg attggatagc
    41101 caagcaagtc cagccacaca aaaaagtttt ttagttggaa atcaaaagga tatgcttgga
    41161 gattccacac gaaatgaaac atcattccta aaaatttttt catactagca gaaagtagat
    41221 ggccattttc ggtcagataa aaagcttgtt caaacagttt accataattt gacaggtttt
    41281 ctgcctctaa ttgataaaaa tagatcattt cttcgatcat cccggcaaac ggccgagtcg
    41341 ttaattgctt tttatttgga tagtttttat acagattttg caaaaaacga tgatcacaaa
    41401 tcattccgca acagataaaa gtcaaaaagt caatctgctt tccgtccacc tgccgctcgc
    41461 tgattgtttg atcataaacg atgcgttctg gcagattgat ggtttgcagc actacacgat
    41521 ttggtagctg caaaatcgtc cgctgcggtg ttaatgctcg gcttagagaa cggatcgata
    41581 cagggatcat ccatagtgat gaatcaaggg ttgtatgttt ttgaaaaaaa cctgccagat
    41641 ccatgatccc ttcatttcca aatccgatga taaacatgga ttgattttcg ggatagcgtt
    41701 tgacgaaatc aagcaggttc tttaattctg ttaaatgatt gcattgagtg ttggcacaaa
    41761 tataccagtc attgtttgct tgatttgcaa ataacgggtt gatcttatct gcaaacaaat
    41821 cataatagcg ctgattcgtt aaaaataaga ttggctgatc aatggaaagt tctcttagct
    41881 gactgactag cgtttctccg taaaacactt tcgtcaacgc atcttctact tgataatcaa
    41941 gttccatacg catccctcct cttcttattt ttattttacc attagtaagc aaattctaga
    42001 aaagataaga gcaaagctca cctcataact tgcaaataaa taaaaattaa ataaaataca
    42061 tgtgttttct atgtatgaca tacggattcg gaatctctgt ctcttattta ttccttttct
    42121 gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc acaagcgctt tttcaactgt
    42181 cttatttaac agcgtctttt aatgctttac ctggtttgaa tgcaggtact ttgctagctg
    42241 gaatttcgat ttcttcacca gtttgtgggt tacgaccttt gcgagctgcg cgttcgcgaa
    42301 cttcaaagtt accaaaaccg attaattgaa ctttttcgcc gttagctaaa gcatcttgaa
    42361 tagttgaaaa tacagcatct actgctgcag ttgcatcttt tttagttaaa tcagtagctg
    42421 aagcaacttt ttcgattaat tctgctttgt ttgccatgga tagattcacc tcctccacaa
    42481 gagatatgat agaaatatca tttagttaaa actttctgag tggtccagaa gtttaaaaag
    42541 aaatattgat taacttcaat attctgttat cacgatatca tatgaaccgc ttaatagcaa
    42601 ggtttttacc aattttcaca tgcttttttt agtcatagaa acgtaacaaa cgaaactgtc
    42661 tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc tattttctcc tacgagggat
    42721 aattcggatg gacgtccctt caaaagtaaa tgcttttctg atttgatttt ctaagaaacg
    42781 ttcataagaa aaatgcatca attcctcttc attgacaaaa acgacaaatg taggtggttt
    42841 gacagcgact tgtgtagcat aaaaaatctt caggcgtttt cctttatctg ttggtgttgg
    42901 attgattgct acagcatcca taatgatatc attcaacaca gccgaagaga tacgaagatt
    42961 ctggttcata cttacttgtt cgatcatttc aggcagacgt tccaaccgtt gtttagtcac
    43021 tgcagaaaca aaaacgattg gagcgtaatc aagataccgg aattcatcac gaatctcttg
    43081 ttcgaaatca cgcattgtat tggtttcttt ctttacaaga tcccatttat tcacgacgat
    43141 aataattcca cgaccagctt catgggcgta acccgctact cgcttgtctt gttcccgaat
    43201 cccttcttca gcattcagta ccatcaaaac gatatcagaa cggtcaatgg cacgcattgc
    43261 acgcatcacg ctgtattttt cagtattttc gtatactttt ccgcgtttac gcataccagc
    43321 tgtatctatc attaagaatt tctgaccact ttcagaaacg aagtgggtgt cgattgcgtc
    43381 tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct tctcctaaaa tcgcattgat
    43441 caaagaggat ttaccaacat ttgggcgacc aatcaaacta aacttaatcg tgtcgtcgtc
    43501 ctcttcttca gtctcttcag agaaatactt cactgcttca tctaaaatat caccaatccc
    43561 tagtccatgg cttcctgaaa caggataagg atcgcctagc cctaaggaat aaaattcata
    43621 gatatcgttt ctcatttctg gattatctac tttattgact gctaaaatca ctggtttatt
    43681 acttctgtat aaaattttcg caaccatctc atctgcgtct gtcacgcctt cgcgtccgct
    43741 gactacacaa atgattacat ctgcttcttc aatcgcgatt tctgcttgat gcttgatctg
    43801 atccataaaa ggttcatcgc caagatcaat tccgcctgtg tcgatcacgc tgaattctcg
    43861 acctaaccat tcaccttttg cataaatacg atcacgagtt actccaggag tatcttcgac
    43921 aatcgagata cgctcaccag cgatgcggtt aaaaatcgta gacttaccga cgttcgggcg
    43981 gccaacgatt gcaattgttg gatttgccat attatttcct cctcacaagt ttccaatctc
    44041 acttagttta acgaatgcat tgccaacttt caagcataga ttgtcaatta aacgaagtat
    44101 ttttattcct tattgaaata ctaatcgctt ttcaaaagaa aaactgagac aaaagcagct
    44161 gctttcatct cagtcacaga tacaaaatca attatttttc agaatcatcg gttgcttttt
    44221 cttctacttc ttctttcaac gcatcaccta aaatgtctcc catagtaaat ccagtatttt
    44281 cttctggtaa ttcataagac tcaacatttt ttggttcttc ttctgaagct ggtttttctt
    44341 ctaaagcttt gatactcaat gcaatacgat gttcttctgg atggatctct aatactttca
    44401 ctttcacttc gtcaccttca tgaagcactt catgtggtgt cgcaatatgt ttatgtgaaa
    44461 tttgagagat atggactagc ccttctactc cagggaacac ttcaacaaag gcaccgaagc
    44521 ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac tggagctttt gtatcgattt
    44581 ctgaccaagg tccaggctgt gtgtctttga ttgacaagga aacacgttct tgttcaggat
    44641 tgatagacaa cactttgaca tttacatcat cattgacagc caatacatca cttggttttg
    44701 ctacatgact atgtgaaatc tctgagacat ggactagacc gtcaattccg cctaggtcga
    44761 caaatgcgcc aaaatcagta agacgtgcaa cacgtccact gagaacatct ccctcatgga
    44821 tagttgaaag aatttctttt ttcttttctt ctctttcgtt ttccactacc gctttatgcg
    44881 ataagatcaa acgattttct gatggttcga tttcgatgat tttaaagctc aatgttttgc
    44941 ctttatagtc tgaaaagtct gcaacaaaat gatcttccac cattgatgca gggacaaaac
    45001 cacgtacacc gacgtcaacg actaaaccgc ctttgacaac atttgtaaca ggtgcttcga
    45061 tgaccttgcc ctcttggaaa tctctttcga tatcttccca aactttttta gcatctaaac
    45121 ggcgttttga aagtagatag ctgccgtttt ctttatcttt gccgatcgta ctgataacga
    45181 ctaaatctaa tacatcaccg acttttacta cttcgctgat atcttctacc ggcaaagttg
    45241 ataattcttt tgccggaacg actccttcaa ctccagcccc ttcgattccg acaatcactt
    45301 gtttgtcttc aatgactaaa acttcgccct taacaacatc gccaactttt acttcttgta
    45361 cgcttttcat tgcgtcttcc attgactggt tgttctcttg attttgatca aattctgtca
    45421 taacacttgt cctcctaacc aacattctgc cgtaagtacg gtactgtttt tagtttaatt
    45481 gattattcaa aaaaaataaa gcgatttcgt tcgttttcct tgaaaaaaca attgtttttc
    45541 attttttttc ttaatttaaa aaagaagata accttttttc aaaacaacag cttttattgc
    45601 tgcaacgact tctggaatcg atttgccagt cgtatcgata cgaacagcat cctctgcttg
    45661 cttcagcgga gagacgtccc ttgttgaatc ataatggtct ctttcctgta tctctttcgt
    45721 cagtgtttca agatcagtcg gaattccttt ttcttggttc tctttgaaac gtctttctgc
    45781 acgctcactt acgcttgcta ctaaaaagat tttcacttct gcattcggta atacagctgt
    45841 cccgatgtct cttccgtcca tgacaacgcc accgcgttcc cctatttttc gttggacagc
    45901 aactaattct tctctgactt ttccatgtgc agagacttca gaaacagctt ttgtgacatc
    45961 tggttgacgg atttctaaag tcacatcttt tgatgctatg aatacatgct gtccatcttc
    46021 ttgttgcgaa aaagagatag gatacttttt gatcagcgaa actagccctt cttcatctga
    46081 aaaagataca ttgttcgtaa tagctaaata agttactgcg cgatacatgg caccggtatc
    46141 tgtataaata taattcaatt cttttgctaa tatcttggca acggtacttt tcccagatga
    46201 agcaggcccg tcgattgcaa tactgatttg tgtcatgata taactccttt ttctcagaaa
    46261 aaaagccgca aagcgcggct attattattt aattcttaat tcttgaccag ggtaaagcat
    46321 aaagttgttt ggatctaagc cattcaattc aaacaattga tcagtggtga tccctgcacg
    46381 ctcagccact tgttttggac cttcgcctgc ttgaacagtc gttgttgaac cggctgcagc
    46441 tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa tcccctgctt gataagttgc
    46501 ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg ctttctgacg ttacacctgt
    46561 atcttgagac acagtagatt cttccgcgat tgtactagat tctactgttg aagtctcagt
    46621 tgactcctct tttgttgtac ttgtagaact ttctactact gatgtcgaag tttcagaaga
    46681 agttgctgct gttgcattgt tgcttgatcc atttctgatc cagaaataag cacctgctgg
    46741 aatagcgata cataagacca gtaaaatcaa aaatagcgaa agaaataatg tatttccttt
    46801 cttttgttgt ctctgagaac ttcttgatga aacttcatca tctgtatcgt agattggttg
    46861 ttcccatggt tcttgtgttt cgttattttc tgtagattga tgtctatctt ttctgctcac
    46921 tgttttacct cctaaactct atcgtgtgta ttataccata ggaaaaagtg tcttgtccta
    46981 aaaaatcaat gttccatgtt ttttttaaat aaatttagta aaatcgttcc ccaatgaagt
    47041 tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt ctgcttttgc tccatcaata
    47101 tcacaacaat tctgcggctt ttcggagagt ttttcgccaa aataagctaa gatgaatttt
    47161 ctgcggcagt tttcttcatt aatatagcga agcatctgct gcaggcggaa ttctttttct
    47221 ttttcctgac gtttgagccg ttccacccaa ttttctggtt tttcagactg ctggatcagc
    47281 tccatccatt ttttttgcag ctcatcaaag ggagcttgct ctgtggcata ttccaaataa
    47341 agctcaaaac tttgtcgctg ttctctagaa agttgattaa agaaataatg gatacgttca
    47401 tccccacttt gataaaaaag aattgctgca ctttcttcct gatctctgcc tgctcgaccg
    47461 atttcttgta catagttttc tagactgtct ggcaaatcat aatggaccac ataacggata
    47521 tcagatttat cgatccccat accaaatgca ttcgtagcaa tgagaaactg cagctgattt
    47581 tttacaaact gctgttgaag ttgtcttctt tgagctgcat caagaccacc gtgatagtat
    47641 ccaactgtaa aacgttccct gaataaatga tacaatcgtt cgacttcttt ttttgttgca
    47701 caataaatga ttgccgctcc ttgtgctctt tccatgaagt gttcaagttc ttgttctttt
    47761 tgctgcgttt tccgaacaaa aagcgagata ttttgccgat tgactgattg tctgatctct
    47821 tttggtggtc gatcaaatag tacatgacgt atatctcttg ctactaaatc tgttgctgtc
    47881 gccgttagtg ccagtgtgac cgggtttcct aaaagctttc ggatttttcc taactgttga
    47941 tattctggac ggaaatcaac tccccattga gacacgcaat gagcctcatc tactacatat
    48001 aacgcaatat tttgtttttt cagatgctct aaaagagaag gattagtcaa catttcggga
    48061 ctcaaaaaca aaaatttata ttgcgataga tgacggagga cgtatcttct ttcagattgc
    48121 gaaagtaaac tattgaaagc agctactcgt ttctcccctc gtttttgtaa ttgcgtcact
    48181 tgatcttcca ttagagaaag cagcggtgac acgatgatga ccagaccttc cattaaatac
    48241 cccgtcaatt gatagcaaag gctttttccc gttcctgtag gcaaaatagc gagagtatct
    48301 tctccatcaa gcaacgcctg aataatttct tcttggccgg gacgaaatga atcaaatcca
    48361 aaatattttt ttaattcatt tattaacatt ctgtatcgct tcctttctca atagatagat
    48421 ttgatacaaa cgaaattctc cataatctaa ttgtccatct acattccatt cgctaaagcg
    48481 ccactctcgc acggaatcct tatttggttc caaacgttcg attgtttctg cagagagaat
    48541 ccactcgtat ggaaaatcat caaaaaacaa ggcccactca ataagatgat ctgttactgt
    48601 tcctcttttt aaatgacgga ttgccatgat ctggtcaatt gtctgaccat tcataaacat
    48661 ctgcttggtg atcatcatgc tttgattgaa attttgctgt aataatgaat cgatcaaagc
    48721 gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac aaaaggtgga tacatctgct
    48781 ttgttgcaga taaaccgctg actcatcatt gttttttgcc agctgataag gaagcagccc
    48841 tgttcgctca tttccagata attggttagc taaaaaatct gctgcttctt ctggtatctc
    48901 cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc aaaatttcac gtggcaattg
    48961 gctttcacta agccattttt ttagttggaa agtataaaaa ggacttgtct ctgctggaag
    49021 atagtcttga atacccgttg ccagattaga aattacttga acagcaaatt taatgagccg
    49081 ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc aaaccagtat gttctatttg
    49141 atgttcggac aacatatcag cccctgcagg cgttagcttt gcttcatttt catttatttc
    49201 gatccaacct tgctgcgcaa ttttttgcaa aatttgataa aacttatcct gcttcaattc
    49261 tggaaaactg ttatggataa acaaaagttc gtgggtaaat ccataaataa gtactgaagt
    49321 cgttcgtttt cccacaagga gttggtaaag agaactaatc cgcagcttgt gtcctgatga
    49381 aaatagcgat aaaataaaaa caatcatatt attctcctta agttaggatg gttagaaatg
    49441 tcactactat gtaaacttgt acctgaacgc tgtattgcat gcggtctttg tcaaatcgaa
    49501 gcgccagata ttttcgatta tgatgaagaa ggaatcgttt tatttgccca agaaccagag
    49561 gctcatcaac agttcgtgat gccggaagaa gaaacatatg taaaaaaagc gtatcaaaaa
    49621 tgtccagttc gagcgatttt attagaaaat aaaatataaa tataaacgaa actttaaaaa
    49681 cgtacactaa gttctctaaa cttgaaaata agccgggatc tgtttctctt gttccgtgaa
    49741 atcccgactt attttgaaag attcatttgc tatctatagt taattgacta gttttttcac
    49801 ggaccctata ggacccattt atattatttc aactttttca gccagttttc caatgtattg
    49861 acgatcacag tttgctggtc tgcgttagaa atttctgcct ctccatctcc tttttgctca
    49921 ccatagctgc caaaacctcc atgatttccg ccattgattg atacatactc tgttctttcc
    49981 ggtaaatact gcttagcttc ttgataagct tcctgattca atactttatc ttttgtcgcc
    50041 gtgatcgata aaacaggaac agctgattct gtcaatgttc cttttttgtc gggataactt
    50101 gccatgaaga ataccccttt taaatgtttg tctgaatgat tcttattgac ataacgactt
    50161 gccattacgc cacctaatga atggccaccg atcacataat cggaatttgg aaaatcttct
    50221 ttgaccttat ccgctttgtt tccgcccatc actgctagat caagtggcat tttgacaata
    50281 gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa tactataact ttctggctct
    50341 acgagagcac caggataaaa aataagtaat ggagactttc catgattctt tttctctcct
    50401 tcaaaaaata agtaatcttc tttgtttttt ccttctttta ccaacacttg cgcttctgac
    50461 gatggttcgt acgtattttg ctgtatatag taataaccgg ctccaccgag taatcctaaa
    50521 atgatgacta agccaattag tattcgtcta aatattttca ctttctccca ccttttctat
    50581 ctgagtgacc cctttttctt aatcaagtat gattatacct taaaaaaata agagagaaat
    50641 gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc atttgaatat ccgccctttt
    50701 tgtatgttta tttttattta gcacataaac gatacacagc ttctgcataa atttccattg
    50761 ctttatacat actacttaat tcccatcgtt cattcgcctg gtgcataaag tcaggagtat
    50821 cagggaacat cgcaccgaat gccacacact ggttcatcgt acgagcaaaa gtagcgccgc
    50881 ctgatacaaa cggttcagtc atgtctccag taatatcgcg atatgtcccc aatagatttt
    50941 tcactaactc actgtctagt ggcacgtata atgaatcaag gaagtcaaat tcttcataag
    51001 tcaacccata tttttctgct gttttagtta atttagctac taaatcatct ttcttgaatg
    51061 taacagggat tctcatatct acaccgattt ttgtttgttc tggtgtgatt tccaaacttg
    51121 caaagttcat cgttagctcg ccggattgtt catcttctgt tttgcccacg acagcttcac
    51181 cagttgcatt ttcttgaact aattttccta agaaattgat tgggccaaaa tcaaatactt
    51241 ctgaaagagc aattgccaga cgagaaatag cattcactcc ttgtgctgca tctttcgcgt
    51301 ggatactttt accaagaacg acgatgcctt caccttgttc ttcgaaatcg aattcgtgtt
    51361 ttttcaatgc ttcttttact tcagaaagct tttctccaga gtaaggagct gcatcaggaa
    51421 caacattcaa cgctcctcca gcttttacag aaaactcgtt cgttcctggt cctgtcaagt
    51481 aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa ttcagcatct ggcgcaaatc
    51541 cttgcgtaat tccttcttct ttttcgttat atttttctaa acaacgccat aaattttctt
    51601 catctgtacc aaagataaaa cgaatacgtg tcttgaattc cacgccagca tcaatcaaag
    51661 ctttgacggc atacattgcc gcaatagaag gacctttgtc atcttgggat ccgcgaccaa
    51721 ctaaccagcc gtcttttata gttggatcga atggttttgt ttcccaatta ttttcgtccc
    51781 ctgctggaac aacgtccata tgacacaaga taccgaataa ttcatctcca gagccaatct
    51841 ctgaataacc gtaatagcct tctggatctt taaatgttct aaatcctagc ttttcactga
    51901 tttccaatac tttatccaaa gcttcaatca cttttttacc gaagggatgt ccttgtcctg
    51961 aatctgcttc atctagtacg gaaggaattc ggatcaattc gctcaatgat tctaatgctt
    52021 gttcatgatg ttgttctgtc acaaattttt tcatgatatt atcctcctaa tatgttaaaa
    52081 agggtcatgt caaattcctc cgacacaacc tcttcttctc aaataatgac gttttaagcc
    52141 tgctccatca gcaagcagaa tgttcttaac aaatgatgaa agaaaaaaca ctcactgaat
    52201 ggagctattg acttatccac gtgcttatcg atagccgttt atcggtttct tcattcttat
    52261 gatagacctt gtacctgtat ttgtctaggt ttagaacatt gctgctacac ctaggatcac
    52321 acagatggct acaaataata tcgcaattaa tttaccggta aatttccacc acactgaaac
    52381 atcgaaacga gcaattgcta cagcacccat tacgatagca gatgttggtg taattaagtt
    52441 tactaaacca gatgcagatt gataagcagt gattactaaa tccttaccga cgccggcaaa
    52501 ttcacccata ggtcccatga ttcccattgt tgcagcagct aagccggaag ttgaaggaat
    52561 caagaatgac atagggatat agaaaataaa tgtaataatg atgaatacac ttgaagataa
    52621 tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct gtgattaatc cattgttcat
    52681 aaccacttgg ataccacgag caacagctac tacgattgct acaccgatca aatcagaagc
    52741 accagctaaa aattcagaga caaattcaga ctctttcatg ccataagtga ttgctactac
    52801 gatggacatt actaagaata acatagtaat ttctgggaag taccagtcac ctaatggaag
    52861 catgctttta cctagaaccg tacctagtac cggaaggttt gttaaccagt ttgtcaatga
    52921 ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga atcaaactga tgatcatgat
    52981 accaaaagta ataaagaaca atacattaac atgtttttgt tttttcgtga ttacttcttg
    53041 acgaccgatt gcttcaatat cgaaatgctt catatcttct ttacgttggt tgtatactaa
    53101 tgattttgtt ggatcttttt cgatctttga tgcataacga tacacatata caatagaaat
    53161 agctaacaaa ataacgaaca tcaagaatcg aagaccaata ccttcaccca tcgaaatccc
    53221 aacagcttgt gaagctacgc ctgttgcaaa aggatttacc gttgaagcta gacagcctac
    53281 ttgagaccct actaatacga ttgctacagc tactactgta tcaaagccta cagccatcat
    53341 gactgggatc agtaaagcat agaatggaat cgtttcttct gccattccgt aagtagagcc
    53401 gcctaatgca aataacagca tcaatactgg aataagcatt ttttcttttc ctttgaattt
    53461 cttcacaact gaagcaatcc cggcatctag tgcccctgtt ttgttgataa tacctaaaaa
    53521 tccaccaaca accaaaatga agaaagagat tgggattgca gcaggtgttt ctttagttag
    53581 ctcccccgct ggtacaccta gcatcccatt gattggcgcc atgaaaatat cccacagccc
    53641 ttgaggattt tgttgtactc gttcatatga tccagcgacg atgttgcctg catcgtctac
    53701 actatagtgc ccagctggta taaaccaagt aagtacagcg attactgcaa taataataaa
    53761 taagaccgta tacgctgaag gcatttgaaa ttttttcttt tttgtttgtt ccatcttctt
    53821 cttcctttct tttccgttag agacaacaat tttggctcta atgttatttt atcaaaaaga
    53881 gtatcagaac aaaaataata acacgcattt tgtaaaactt ttgttcaaaa agttcgtttt
    53941 tccctattcc ctcctctttt ttcaggtttt taaagctttc ttctttttca ttgtagcgtt
    54001 tccttttttt tataaacaaa cattttcgtc ttttaaaagg agaagaattt cacatttgca
    54061 aagaattgat tgatttttat gcataaatca aaaaaatact caaaacaaac aaataaaacg
    54121 tttacattat tgcatgtctt gtattttttt ccaaaaaaaa agaccaagaa atttcttgat
    54181 ctttttgata tttatttgac tgctgtatga cgttgttcga actgatgttg ttttcgactt
    54241 aaccatggaa gaagttgcgc atgcagcact aaaaagacag cactcacgat gaatcctttg
    54301 atcaagttga aaggaacgat cccaatcagt acatagtttg ctaaagacat gcccagcatc
    54361 tgtgttgcgt tcagccctaa aaacattaag taaagaggcg taataacgaa ataatttgcg
    54421 atactcataa aaatagttag agcgatggtt cctgtaatga cacctaaaaa tttgtttctt
    54481 cctttatgct gtttctttac actaaagaaa taataaatcg ggaatgtaaa gatcgttgtt
    54541 gataagaaac tagcagtgtc tcctaccaaa ttatccggag aaaaacctgt agtcagcaga
    54601 tgtaatactg aacgcaagaa cgctgttgca actccggccg ctggaccgaa taagaacatg
    54661 ctgatcaata ccgagatatc actaaaatcg atcttcaaaa aactaaaagc cggcatgatc
    54721 ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa acatcgctac tgcaaccatt
    54781 ttctgtacac gggtgttctt catttgaaat cctcctgtta ggactcctct tcagcgaact
    54841 ttttgacgtt tctctccaaa tgaaaaaact ctattttcca gggaaaatag agttagagtt
    54901 atttgatcaa gcgtcgtcaa ataagctcta tcttctttat ccagactata ctgtcggtat
    54961 cggaatttca ccgattcagc tatttttttg caaaataggt cgtggactat aaccaccggt
    55021 cgggaatttc accctgcccc tgaagacgaa ccttatataa tttttgttta catattcatt
    55081 atacatatct attcaaaaaa cgcaacatct aacacttata aaaagtaagt gttcattttg
    55141 agtggttcag caaactgctg acttcttttt tgttcagttc acggtaatcc ccaggacgta
    55201 ggccttgtaa agtcagatct ccgtattttt cacgttttag tttttgcaca ggaagaccaa
    55261 ctgcttgaag catatttttc acttgatgat tacgtccttc gtggatcgtc aattccacga
    55321 tactgtggtt tgtcttagga tccactgata aaatttggaa tttagctgga gatgtttttc
    55381 gtccttcgat ctttattcct tttgtcaaag gtgcaagcat cgattttgta gcgatccctt
    55441 ttacctttgc aacgtaaact ttatccactt catgttttgg atgtgtcagg cgctgagcaa
    55501 aatctccatc atttgtcagt agcaagatcc ccgaagtatc gtaatccagt cgacctacag
    55561 gatagatacg ttcttttacc atcggcaaaa gatccgtaac aacttttctt cctttgtcat
    55621 ctgcaacagc agaaataact cctttaggtt tgtacaataa atagtaaccg tattcttctt
    55681 gataaattgg gacttcatcc acttccacag tgtcatgttt cccaactttt atccctaatt
    55741 cccttacaac ttgtccgttt acttttacac gtcctgcaag gatgaattct tctgcttttc
    55801 gacgagaagt gatgccagcg tgggcaatta ctttctgcaa tctctccatt acaattattc
    55861 tcctttattc attccatcaa agaatagatc tggtgacacg tcttcttcaa gtgaaatttc
    55921 catttcttgt gtatcaggca gttcttctaa tgatttcaaa ccaaaataat ctaagaagta
    55981 gccagttgtt ccatataata tcggccgacc tggtccttct actctacctt tttcttcaat
    56041 cagtttatgg gcagctagac gctgtaccgc tcctgaaacc tgaactcctc gaatctgctc
    56101 gatttcagct cttgtgattg gctgtttata agcgatgatt gctaaggttt cgacggcggc
    56161 ttgagataat gtgtttgatg tcccttgcgc atatcgctta agtaagggag ccagctcttt
    56221 tttagtcgtt aatacataat ggctttccgt ttcaaaaata tgcaaagctg agtgcgagtt
    56281 ttgagtgtaa gattctttta attctttcac taaacttgtg acttctgctt cgctgagatt
    56341 taacagtccg cttaattctt cattactgat cccttcctcg ccaacaataa aaagaagggc
    56401 ttcaagttca cttaatttcg tcatgttcgg tatctcctac tgctggataa agcataattg
    56461 attcatagtt ttctttttgt tgcgcaatga tctgcccttt tttcatcaat tctagcaaag
    56521 ccataaaagt agtgacaact tcacttttag aaggtgactc aaaaaaagaa tcgaaagtac
    56581 agccatgcgc atttcttttt atacgctctt cgataaatac cattcgttct tcgatcgttg
    56641 tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa tttcttacgt tctaagattt
    56701 tctgcatggc acggatcaaa tcgatttttt tgacttgtcc tcgcttcaac ggcttttcag
    56761 catccgctaa cccatcgatg ttcataggtt cttttgtgta ataaagactt cgttcctctg
    56821 ctttttctgt cagtctttca gctgcatatt tatatttacg gtattctaaa agctgagtga
    56881 ccaattcttc tcgaggatct tcttcccata attcttcatc gtctgtgacg aattcttgga
    56941 caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc agccatcact aagtattctc
    57001 ctgcaacagc tagctcgagt gttttcattg tatggatata attcatatat tgctccgtga
    57061 tcgtagcgat cggtatatca tatatatcga tttccatttg ctgaatcaga tgaagcagca
    57121 gatcgagagg accctcgaat acatctaatt taatattgat ctccgtcaac tcattcactc
    57181 tttcttcttt ttctttgcta gccattttcc aatgtaaggc tctgtgattt cagttgcacg
    57241 gatggagaca tccgggtact tttcctgtaa ttcatctaac atttgaaagc ccatattctc
    57301 accgcgataa gacggattca aagaaatgtc atggatgatc agctgatcgt tcgttgccca
    57361 gtaaatacca ataatccctt gaatgttggt tgaaccttct ggcgtaaaga aaaaaagttc
    57421 ataatcgtct tcagattcgt acgtatcaat ctccttcaac aaagaagttt tacctgtcag
    57481 tttcttatgg aaactcaata gtcccatagc aattttacgg ttttctttcc ggtaatgtgt
    57541 taacatcttc tcaccttcct atgactaagc ccttggaaaa tgctgcttat aaacatccgt
    57601 cattcttttc ttcgtgatat gtgtataaat ctgagtcgta gagatatccg cgtgacctaa
    57661 caattcctgt actgtccgca aatcagctcc attttctagc agatgtgtgg caaagctatg
    57721 ccgcagcgta tgtggtgtta cttctttgta aatcccagcc tctcgtacta actgcttcag
    57781 atttttccag attccttgcc gagaaagacc tttcccatga ttattgacaa atacatgcat
    57841 ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct aagtagcgtt ccagccattg
    57901 gatcgcataa tcacctaaag gaatgatccg ctctttatct ccttttccaa ctgtctgtac
    57961 cagtccaaga gaaagatgaa gatctcccaa tttcaatcca atcaattcac tgacgcgcat
    58021 cccagtagca tacatgactt ccaagattgc acgatctctt atccctaacg tttttgtcgt
    58081 atcaggtgct tcaatcagct tttctacttc tgtcagagtc aatgtacttg gtaatttctg
    58141 tgctttcttc ggcgtatcga tatgttgcat cggatcatga tcagtgatac gctcttgccg
    58201 taaaaactga tggaatcttc tgagacttga gatcatccga gtaacagttg ctgtcgcttt
    58261 tttttcttca tgcaacttct ccagaaaacg gatgactaaa aagcgatcga catcctgcca
    58321 tgaagcaatt ttctgctcct gtagaaaatg caagtactgt tccaaatcac gttcatagct
    58381 ttgtcgtgta ttggcggaca atccccgttc aatattcaag tagtggagat aatcgttgat
    58441 ttgctctttc ataataatcc ccctcatgcc tctctatcat atcagatacc gcttcattct
    58501 gatagtcttt ttccataatc tgagcaaaga aaaagccgtc tagacactca gacggactgg
    58561 tttctttttt ctttttcata gcattcctga cagattccat ggaacgttag ccgatgatct
    58621 tttactaaaa aatgataacg ttcttctact acttgctcca cttcaagtaa aagatcctct
    58681 tctacttcct cgatcgtgcc gcagttcaag catagtaaat gatgatggaa atgtttggcg
    58741 ccttcttttc tcaaatcata acgggctaat ccatcattaa aacttacttt atcgacaatt
    58801 ttcaattctg tcaagatttc aagggttcga taaacagtag caagtccaat ttccggactc
    58861 ttttttttca ctaaaaagaa gatttcttct gcagataaat gctctttctc attttccaaa
    58921 agcacaagca gagtagcttc tctttgcggt gtcagcttaa accccgcttc atgtagctgc
    58981 tgttttgttt ttttcatcgc cgaaatagca ttcatgacca tttactcaac cccaacaatt
    59041 tataataatt acaaataaaa aaagatataa cactatgtta attaaaatta ttataagcta
    59101 gttaagaaaa acatgcaagg gattctcaat tagatttttt gactagtttt gtcacaccgt
    59161 tttcttgtgt aatcaatcct tgtttcaaaa gattacctaa tgcgcgctta aatgctcctt
    59221 tgctgatacc aaaagctttc atgatttctt ctggatccga tttatctgta aagttgattt
    59281 gctgatctgc agaacgttct aaaatggtta aaatcatttg tgcatcatct gatatagctt
    59341 catatgctct tggcttcaat gaaagattca gtacaccgtc tggtcggaca ccaatcactc
    59401 gaccttttat ctgctcgcct agacgaggtt cattatatcg ttcagaagga tggataaacc
    59461 caagatagaa atcttccgtt aaaacgtacg tacctgttaa tttcaagcgg tatgctgttc
    59521 ctatcacatc tttgtttttc atttcttctg ttccatattt gcttaaagat ttgaatattt
    59581 tttcatctgc taaactgccc caaatacggt cttttgcatc aactctaagg gaaatcatca
    59641 agcgatcccc ttttttaggc catagctctg tcattgtcgg caattcatca agagatacga
    59701 caaagtcttt atctggaaga ccgatatcga caaacgcacc taaatctttt cgtgtagcag
    59761 taacgattcc aaaagcgtaa tgaccgatac ggcttttagg aatttgtgta gtgatccgat
    59821 tttcatgttt ttgattttgg taaccgaatc cttcaactgc ttcaccgatt ttgtgttcac
    59881 cttctgattt gcttaagcca aaggtttgtc cgtttttttg gacaaagtag tttttttcat
    59941 tttcatcaat aataatacct gtaaatatag ttgctaataa atcgttcatt tttttctccc
    60001 tctatagtga aaggttttct taatacattt ctttgctatc ataacataat gttatctact
    60061 tgaatagctg agccttggtt tggaaaggtg aaaaaaggag tatgacaaca gttgtgtcat
    60121 actccccttt ttcgaataaa cggtgttaaa cggcaggctc acagcctctt tcatttgcct
    60181 aaaattaatt gctcccattt cctccgaacc atccagtttt acagttgatg gttacgatgt
    60241 aaaatggcaa agcactttct ccaatgcctt tcatcaatgc agattttgtt gaagtggcat
    60301 atagattata atagccttcc ccattttcga ttctggcttt ttctaatctg taacctcctt
    60361 caacgatata tccacgttgg atacatgtag caatcacttt gctttggaca cctggtgccc
    60421 acgtccatgc tggattagat gcatcggcaa tatcacttgc tctggcagat ttgattggct
    60481 gattcgctga gtttgaagag gaaggggtcg aggatgccgc ttcttgctgt gctgcttgtg
    60541 cgaccgcagc ttgttgagcg gcttgagctg cagctgctgc ttgagcggct tgttttgctt
    60601 gttcttcagc tgcttttttc gcttcttctg cttttttctt ttcctcttct tcttttttct
    60661 ctttatcagt gagcatctta tctacttgtt tcaattgttc attcaactga gcagatagat
    60721 ctgtattttt cactttttct actgcttctt ttgccgtctt gtattggtcg cgtgttgctg
    60781 aatccactac ttttccgtct ttaaagacta tagctgtttt ttctttagct gtttgcaatt
    60841 cagcatattg atttttagct tctgtttgtg cttgttgaat caattttcca aaatctgtgt
    60901 tatccgtttc gattgcttgg atctctttat ctgctttcaa cttgatgtca tctgctagat
    60961 gatcatcgac gatggcaggt gctatgaacc actcattcac tttttggata tctcggatct
    61021 tagattggat atcttggtaa gttgtttcta actctgaata tcctttttca ttcttaagac
    61081 tggataaatc attttttagt tttgataaat cttgatgaat catatctgca cgaataaatt
    61141 gatggtgatc atctgtataa aaggcagcaa gtttctcatg aagttcttcc atttgttgct
    61201 gtctttttgc ttctgctgct acttcggctt ctactttttg atgatggtca taataagccc
    61261 agcttcctcc accgagtaga agtactgctg ctaaaacgag ataaggtact ttttttgatt
    61321 ttttcttttg cgctttatct ggatctgttt tttctaagtt tgattcttga tgtgtttttt
    61381 cagtatctgg cacgattgtt attgatttcg cttctgcttc aaacagctta ggctggttct
    61441 cttctttttc tatttttgct tcaagatcag taccctcttt gcttacagat tgattttcag
    61501 catcggattc actatttatt tcatcgggct ctgttgactt tttgtctgtg ttttcgagta
    61561 tttctttttt ctctgcttcc ggcagtttat tcgttttttc cttttctaat tgtttttcag
    61621 taaatacttc agttttttct gtgatatccg tttttacgtc ttttattttt actgtttctt
    61681 tacctgtggc gttttctcta tcagagtctt tttcagtttc ttgttccttt tctggctcta
    61741 ctttgttttc ctgtgcaatt ttttcactga tcattttgag cagctctttc gcgtgctctt
    61801 cttttgtatc ttcacgatgt gctttgatat aagcggatag tatcgaattt tcttcctcat
    61861 tatcgacgat ttctttcagt tcagctactc ttcttttttg ttttgattca agcgtttctt
    61921 cttgattctt tcctgattct tccgaagtct catgaacagt tgctttcttc tgttcatttt
    61981 tctctatatt agttacttga tcgtgagcag gtggttcttc gtcttctggt tctgcttttt
    62041 cgaataattc cattacagat tctagaggta aatctttcaa ttccgaccat tcgattggat
    62101 cgtttaattc tgtatcagga aagactgcat cttcagttga tttatcctgc atagctgcat
    62161 ctgtatttgt ttcttcaatt gattctttta tttgctgatc ttctgcagtt atttgatgac
    62221 cgcagtctgg acagatagta ttctgctcca tttttttcga tccgcaattt ggacattttt
    62281 tcatcactta gcgatcggct cctttactag gtttacgcta ccatttaatc tatcatattc
    62341 tatacgtcac gccaatagct tatttttagg atttacttaa aaataatgaa tgaatttcct
    62401 tcctatagaa aaaaaagctt gagactgcgt agtctcaagc tttttttctt ttaaaataaa
    62461 ccaaacagtt ttactgattt ctcttctggt caatagtcca cgcttattct aagaaatctt
    62521 ttaattgttt tgaacgagaa ggatggcgca attttcttaa tgctttagcc tcgatctgac
    62581 gaatacgttc ccgagtaaca ccaaatactt tccctacttc ttccaatgtt ctcgtccggc
    62641 catcatctaa accaaaacgt aagcgaagga cattctcttc ccgatcagtc aatgtatcta
    62701 gtacatcttc caattgttct tttagtaact cataagctgc gtgttctgct ggacttgttg
    62761 cttcctggtc ttctatgaaa tcacctaagt gagagtcatc ttcttcaccg attggcgttt
    62821 caagggaaac aggttcttgc gcgattttca agatttctcg gactttttct gttggaagat
    62881 ccatttccgc accgatttct tctggcgtag gttctcttcc aaggtcttgc agcaattgac
    62941 gttggatacg tatcaattta ttaattgttt caaccatatg aactggaata cggatcgtac
    63001 gtgcttggtc agcgattgct cgagtgatgg cttgacgaat ccaccatgta gcataggttg
    63061 aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc cttcatcagt cccatgtttc
    63121 cttcttggat caagtcaagg aactgcatgc ctcgtcctac ataacgttta gcgatactta
    63181 ctactaaacg aaggtttgct tctgccagac gctgtttcgc ttcttggtcg ccttcttcga
    63241 ttttcaatgc taacgctact tcttcttccg cagttaaaag ggagacacgg ccaatttctt
    63301 tcagatacat acgaaccggg tcattgattt ttacaccggt tggcgcagaa agatcttctg
    63361 tttttgcttg ttcagctttt ttctcagcac tcttcaagct gtgaattgat ggatcaccat
    63421 tttcatccac cacactgata cctgcgtctt caatcttttg gatcaatttg tccatttcat
    63481 ctgcattcaa agtgaatggt gtagcaagct gattggataa atcatcatat acaacttgtc
    63541 gtttgggttt gttttctttg atgaaagctg ctactgctgc ttcatacgtt tttttatctg
    63601 ttccatttgc cataaaagaa ggcccccctt gagtagctat ttggcttgtt ttaactgttt
    63661 cgttaaattg atgatttcaa tcgtcaattc aagctcaagc tgtttgtttc cagttcgtct
    63721 ggcttcttgc tgcatttgtt tttttaatgt tatttcatca gctaagccag atttgctgat
    63781 cacatctagc aagtcttgga tttctcgtgg cgaactttct tctgccaccg gtaaatattc
    63841 gatttccacc accaaccgcc ttaaattttc atcttgcaaa aagtctaaaa actctgcaag
    63901 gttgaattca taatgttgtg agacatatgc atcgaataaa aaataaactt ctgcatatgc
    63961 atcatgaata aactgaaatt ctcgttcttt taaaatatta cggacagaaa cttctttaaa
    64021 tgcacgatat aatagaatct gctctgcctt ttctacttgc gtcaaaggtc tctttttccg
    64081 tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc tgaggttctt gacgattttg
    64141 ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc gtctctctgc cgatctgaaa
    64201 ctctgttgac agttgagata gatacatatc ttgttcgatt ggtgaaacaa ctcggctaag
    64261 ttcaactagt aattcttcga ggtattcgat cttgtctttt tcattatcta aatttttccc
    64321 ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg cgcccatgag ccactaattc
    64381 ttggaaagat gcttctccat acttacggag atattcatca ggatcaagct tttctggaac
    64441 gactacgaca gaaagtgcta atcgactgtt ttgccgaagc aattcaatcc ctcgattggt
    64501 tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc aattctttcg tcagcttttc
    64561 catttgttgg atctgttgag ctgttagact tgtccccata gaagctaatc cagttttgat
    64621 accagcctgc catgcagcaa tcacatccat aaacccttcg aacaacaaaa tttctccgtt
    64681 tttccggata tcgcttcttg ctttatcaag attaaataaa acttgtcttt tattgaacag
    64741 ttctgtttct ggactattca agtatttggg ctgatctttt tcctgccctt tttcaggtgc
    64801 aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa ttacgaagtg gaaacatcac
    64861 tctttgataa aaacgatcag acatacggcc atcatcatgc gtgacaaaca atccagagcg
    64921 ttctaacaat tcatttgaaa ttgattcatt cttgaatact tgctgaagaa aagaacgctc
    64981 attaggtgca aaacctatgt tgaattcttc aattaattct aaagacaacc cacgactttg
    65041 caaatattct aaagctggct gtccagcttt tgtatgcaat agcatgtgat gatagatttc
    65101 cgctgctttt tcatgagcag caatcagttt ccccgtagca gattcaggat tttggacagc
    65161 tatagtacgc tgacgccatt gatcttctaa cggtatctgt tcgaagtctg ccacttttac
    65221 cactgcttct ggaaaactta gaccttctag ttcttgaaga aaagtaaaca cgtttccgcc
    65281 tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct gcaacagaaa aagacggtgt
    65341 acgttcttca tgaaaaggac acagccccaa gtaattttta ccagactttt tcaactggac
    65401 atattgtcca atcacctcaa cgatattcgt ttgactgcgt actgtttcga taacctcttg
    65461 aggaatccgt tgagccattt tttcaccccc tgctctattg atatcttttg ggtttaacag
    65521 aagatatttc aggagaataa ccggtaaaaa atcgcactaa ctgaaatcag tgcgatttta
    65581 aaggacacaa ttatacatgt ttgattgtat catatttcat tgctttttca agtataacac
    65641 atttctatct cattaagcat caatttgcta ctcttttcag taactgattt tgaatatcag
    65701 ccttccagta caatactcga agaacaatat ttacgagcat gaatacaaag aagtatccta
    65761 cgctctctcc caaccctaag tttacttcca aaattccatg gaacagcatt gcagctacat
    65821 atatccctac gatcgtcgtt actgctagga agatgcgcaa tgggttgaag ggataacaag
    65881 cttttacaac tgccatgcaa ctgatcccaa tcagcaagta atacatcaaa gtagtagttt
    65941 cagcatttcc ccatgcgaat gtttttccaa gtagatacac cgcaatgata ttcactacta
    66001 caagcaaggc atttggtaaa gcattaataa gtgctgtagg caaataacgg taagtgattt
    66061 ttcttttatc ttgttcaaaa gataaaaaga aggaaggata cccttcaatc gctaaatcaa
    66121 tcagcgtgat ttggataggg ataaacggaa atccaattgc tgtaacggca catataatcg
    66181 ataaaataaa tgaataaatc gttttgataa aaaagatgcc tgagactttc gtcacattgt
    66241 tgaccactcg gcgtccttca aacaggactt ctggcaatgt agtaaaatca gagtccaaca
    66301 ataccagatt cgcaatctga cgtgttgctc catcaccttc tgccatagca atgctgcaat
    66361 ctgcttctct taacgccaaa acatcattca caccgtcgcc tgtcattgca accgttctgc
    66421 cgctttcttt caattcattt accagcaatt tcttttgctg cggactcact cgtccaaaaa
    66481 ccgtatagcg atgagcagct tctcgcactt ccatttcttc agtaatttga gaaagatcga
    66541 catacgcatc ataattcggt aatcctgcac gtctagcgat attggagaca gtaaaaggat
    66601 tgtctccaga aatcactttc agatccacac cttcctcatg aagataagct agtgtttctt
    66661 gagcgttttt tcggattgga tcatcgattt caaacagagc aaccggctca acaaatgctg
    66721 gtttttcttc gttcaattgc tgatttggag cgatccccaa cataagtacg cgatagccat
    66781 tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc ttccaccaaa cgttcaggcg
    66841 ctcctacgta cacgactccc agttctggaa attccatcgc gccccatttg cgatcagaag
    66901 aaaatgcgac tttgtttgtc acatcatacc gattagaaag ctcaaaataa tctctcatag
    66961 cccgcatagt gatgttgtta tcactgcttt ctgccagata cgtccccata atttctggga
    67021 tggctttctc gtacagcgga tgtagtgctt ctacccgctg gatactcatt ttcccttcag
    67081 taatggtccc tgttttatcc aagcataatg tatcgacatg ggccagcgtt tcaattgaat
    67141 acatgtcttg aacaaggatt cgtttttttg ccagtttggt tacccctgtc gttaatgcaa
    67201 tacttattag caataccaaa ccctttggaa gcatgcctaa caaagctgct gcagatgcaa
    67261 taacagaaat tttgatagaa gcatcgcgga tgaacagtgc ttccaaaaat agtatgatcc
    67321 ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt gcgaatcgaa tctacaagtt
    67381 cagaacgaat agctttgtga gtctttgcct cgctagtcaa gcggacagca taattatctg
    67441 cacctactcg gataacttca gccatgacag aaccgcttgt caaaaagctt ccagaaagca
    67501 attcagctcc agtttctttg acaatcaaat cagattcgcc tgtcaaaaga gcttcatttg
    67561 cttctgcccg tccagatata acctgtaaat cggctggtat ctgttctcct gctccgattt
    67621 ttaccaaatc tcctaatacc agctctttag tagaaatcga ttgttcttta ccgtcccgga
    67681 tcactagtac ttctgattgg gaaacaatcg ataatttccg tacaagattt cttgcatgta
    67741 tttcttgata aattccaata acgatattga cgacaataat tgctaaatac gccatgttgg
    67801 aatacgcacc tacaaataac agacaaatcc caataccaaa gttcagaaaa ttgaataacg
    67861 tcaatatatt atcgctgaat atttgttttg tactttttga tgcatcttcc tggtagtcat
    67921 tttgctggcc agaagccatt ttctgaacta cctcttgctg tgtaagtcca ttcattttct
    67981 ttttctccat tttccgccaa ctttcaaaaa taatcacgtg tttaagtcta gcgtgttcca
    68041 agattaaaaa caacttgttt ttataaaatt tatagaaaaa cacacgaatg attttacaaa
    68101 aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt ttttattatc aatctatctt
    68161 tacttatatt gttcctccaa acggctcatc caccaaccta gtgctgtacc ggctataaaa
    68221 agaacaggac aagctagtac cccagcaact cccaatcccg cgtaatcggt aggaatgatc
    68281 ataatcgttg aagcaaaaac tacacctaaa atgaaatgga atagcttgct atatgccttt
    68341 gagaaaatgt aatccatgat ttttgacaat ccaagaacac aaagaatccc accaattccg
    68401 atcggcacaa tcacttcaag tcgtacttct ttaaatccgt cagccatcgc tttatacaat
    68461 cccatataca ccaaaaaatt agaagggctc aatcctggga cgatcatacc caaaccaatc
    68521 aatccgccgg caatcagcca tgttccaaaa ttctgatcga cttgcccgtc aaataattga
    68581 gcgccgtata ataaaaacaa ataagccaga acaaaagtaa caaccatgat gatcacatca
    68641 gaagtatctc ttcctttttt ccctgcttct ttccataacg caggaacagt tccagcgata
    68701 catccgacaa aaaaccataa tatcgttgtt tcatacgcac ctaataaaaa actgactaaa
    68761 aaagaaagta gaaagatgcc tgtcactccg cctagaccaa caggcagaaa aaacaaaaca
    68821 ttttctttga aattttttgt aaggtgggct aaaaaagaaa tcagccgctc atacatgcca
    68881 aagacagctg ctaatgcacc accgctgact cctggcaaga taaatcctga accgataaac
    68941 attcccttca caaaccgtaa catccagtct ttggttgtgt accccacttc ttgattttcc
    69001 attttttgcc ttttttccac tatttgcgta ctccttcttt catttaattt tattcatgat
    69061 tgaacatttc ctgctatttt acttaaagac tttttcatag gtctctatta ttttttcatt
    69121 cattttgaca atatcaggat aaaacatgtt acctccatta tgatagagat agccgccatt
    69181 gtaaagcaag gactggatcc gccaatatcg gtattgtttc ccttcctcat ttcctaaaag
    69241 tgggctcagc acatctttag aatacgcttc tgctaattct actgtgtttt ctccgccatg
    69301 attttttaca taggcaatat aatctttccc aaaattatat gcttggacag ctgtccataa
    69361 atcgcatcct tgtttctttg cttctactat catttccgcc aaatatttga caccttgatc
    69421 aatactgtca gctggattat caatgatctc agcttctcca tgcagacttt ccgagctctg
    69481 catgagatct gtcccttttc cttttgattc ggtcaatatt atcgccttga tcaaattctc
    69541 gtagttttcc atatgataat tttttgcagc tgttgttatt tctatttgat agctttccac
    69601 tcgttttacc gaacgataag ttcttcctca taaaaacaac accgcaccaa taaccgtcag
    69661 aatgatcatg taaaaaagaa tacggataat agataatcgt tttcgcttca tttcatcacc
    69721 tagttatttt gacatctttt tttatcttac tatttcttta tcttcttggc tatttcttcc
    69781 ttgatttctg tgtacgcctt aagaaaaaat gaattttcct gtattttttg acatcttacg
    69841 aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg actgatataa tcgttatact
    69901 ttacacagta ggtgattatg tgaaaaaaga aaagaaatat gcaaaaatgc cagatgggag
    69961 cgaaatttac tatgaaaaga gcggtcaagg cttccctctc tttttactgc atggcaatga
    70021 cggcagcggc cgcttttttt cagaacaggt ccctgtactc gaacgctact ataccgtgta
    70081 tctagtagat agccgaggac atggtcgttc gacaaacgaa gcatctatgt tgaattttca
    70141 gttaatggcc gaggatctga atacgatcat gttgctggaa aaaatcgatc aggcagattt
    70201 tcttggattt agtgatggag caaatctagc actggtattt gccagcagct tccctaaaaa
    70261 agttcatcga ttgattttaa attctggaaa cacgcttgtt aaaggcgttc gtttttctgc
    70321 cagagtcatc agtaatattc attatgcatg ggtatggtta ctctctttat ttcgcccaag
    70381 tcttcgcaaa aatcttttag ttatcaaact tttgctgcat gacatcgggc ttacagaaaa
    70441 tgatttaaaa aaaatcaact cccccacttt gatcatcgtg ggaaaaaaag atgtaatcaa
    70501 gctaaaacat tctttgtata tagctaaaac tataccaaaa gcttcctttg tgcttgtgaa
    70561 agaacaagga catgaattag ctagaaaaga tcctgaacgc ttcaatcgag aagttcttca
    70621 atttctttct gaaacataac tattaggaat agaaggtgat ttatttgtta aaaaatacca
    70681 tacaatggct gaaaaaccac ctaggactgt tcaaaacaat ctttttgatt tctgtcattg
    70741 tcattattgt cggtgaattg atgtccatcg gtaaaactct atctatccag caattaggag
    70801 aaacgtttgc cactatacct gtatggaaaa gcggactaat gctattgatt ggtcttatct
    70861 ctgtgttacc tatggttggt tatgatatta ttttgaatcg gatgcttgaa caaaagcaga
    70921 atcctcgtta cctgtttgag acaagctggc tgatcaatac gatcaacaat attgccggtt
    70981 tcggcgggtt tgttagtgtg gggcttcgct ctgaactata tggacaaaag aaagagagca
    71041 gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt gatggctgga ctttctattt
    71101 acagtctgct ttctttttta cttgtagtct tcacgccagt tgctcctttt ttgaagcaat
    71161 attggatatg gttgatcggc ggcggtctat attttcctgt cgtcttttta tttactactt
    71221 tcaaaaagaa aggattcctt ggtggtacct cacttaaaac tcaaggacag ctattgctag
    71281 tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct ttctgttggt tatttaatgg
    71341 aaatccggat tgatctgtgg caaacaattc cattattcat tgctgcttca gtgataggaa
    71401 tcgtgtctat gattccagga gaaattggga gtttcgatgt aatgatgatt atcgggttgt
    71461 ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat cttgctctat cgcctgttct
    71521 actacatcat tccgtttttg attggaatcg tctttttctt caaaaatatc ggttccactt
    71581 ttgatcagcg ttattctggt atccctaaac aattagcaac agaaattgcg cataaaatcg
    71641 tggttgtctt attatacttt tctggaatca tgctagtact ttctgccact atcccgcaag
    71701 cttttacaga gtttcgctgg cttcatagtt tgaacccatt gaaatttcat tttattatcc
    71761 aatttcctag tatactattg ggatttcttt taatcattat gggcagaggg atcgcagcac
    71821 gtgtgaaacg agcatatttg cctacaatct tcttgattgt tctagcttta ctttatgttt
    71881 tattaagtga ttttagtttc acaccggtgg ttttcttgtc tattctgctt ctgatcattc
    71941 ttgcttctaa aaacgaatta tttcgggaac aattgatcta ttcatgggag tggcgtacga
    72001 tcgatggaat cattattggt gcactgtcct tgctttacat cgttattggg gtatacaatc
    72061 tgccggattt ccctcatcgg cgtcaccatt ttatttcctt tttcttattt ccttctgaaa
    72121 agatttggtt ttcgggattg ttggccatca tcgctgttag tttcatgatc gttctatttg
    72181 ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc ctttaatgaa gaaaaggccc
    72241 tgaagatcct tacaacttat ggaggaaact ccgatagtca attgatcttc ttaaaagata
    72301 agcggatgtt tgcctatgaa aaagacggtg aaccaactgt tcttctccaa ttcgcttgct
    72361 tcaataataa atgtattgta atgggtgatc cttctggtaa gaaagaagat tttccagaag
    72421 caatcgaagc ttttatcgaa gaaacagatc gactatgcta tttaccagtt ttctacgaaa
    72481 caagcgaaga gattgttatg attttgcatg aattcggcta cgatttcatt aagatggggg
    72541 aagaagctta tgtagacctg aatagtttta caacttcagg gaaaaaaatg aagggcactc
    72601 gtgctgtctt gaatcggatc gaacgagaag gatttacatt tgatgtctta caaccaccat
    72661 tttctactga gcaaatgagt actttcaaaa atatctctga taattggttg ggttcacgaa
    72721 aggaaaaagg gttttcttta ggctttttct ctgaagatta tctacaaaga gcgcctattg
    72781 cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc aacgatcatg cctacttaca
    72841 cgaacaataa agtaggaacg attgatctga tgcgatatga ttctaaaaaa gcaccttctg
    72901 gcagtatgga tttcttgttc ttgcatttgt ttgcctatat gaaagaagaa catatccaat
    72961 ggttcaattt agggatggcc cctctttcaa atgtcggaac ttccagaaag agttttttac
    73021 aggaaaggat tgcatacttg gtttacgagt ttggttctca tttttattct ttccatggat
    73081 taagagaata taaaagcaag tacgctacaa actgggtctc acgttatact ctatattcta
    73141 gagatagttg gattgcatat gttatgattg ctttgctgat tattgataat gcgccagttg
    73201 agcagacaca aggtagaata agtggtttga aaaaatggat acgaagaaag tattaaaaac
    73261 tgcataccga tagatgaaca ctctcatgat gaataaaaga gactgaagta aaacgaaagt
    73321 tcatgcttct acaatctctt cttatacaat tgaagaacaa agagcggtcc aaacagaaat
    73381 cctgtttgga ccgctctttt attttaaaca tttttcatta ccaaaatatt cgagtcgcgt
    73441 ttcttatgct tcgatctctg taacgatacc tgaacctact gtccgtccgc cttcacgaat
    73501 tgagaatgtc gttccgtttt caacagcgat tggatggatc aagtcaacat caatcgtcac
    73561 gttgtcacca ggcatgacca tttctgtatc ttctggcaat gtgattgttc ctgtaacatc
    73621 agttgtgcgg aagtagaact gtggacgata gttgttgaag aatggagtat gacgtccacc
    73681 ttcttctttt gtcaacacgt acacttctgc tttgaatttt gtatgtggag taatggaacc
    73741 tggtttagca agtacttgtc cacgttcgat atcgtcacgt tggatccccc gtaacaacac
    73801 gcctacgtta tccccagctt ccccgtaatc taacgtttta cggaacattt ctacacctgt
    73861 tacaactgct ttttgtgttt caggtttgat ccctacgatc tctacctcat caccgacacg
    73921 aacagcacca cgatcaatac gacctgaggc aacagttcct cgacctgtaa ttgagaagac
    73981 gtcttccact ggcaatagta atggtttatc tgtatcacgt tctggtgttg ggatatattc
    74041 atctactgta tccatcaatt ccataatagc agcttcagca tctggatcgc cttgcaatgc
    74101 ttttaatgcg gaacctttga tcacaggagt gtcatcgcct gggaaaccat attcgctcaa
    74161 taactcgcga acttccattt ctaccaaatc gatcaattct tcatcatcga ctaaatcaac
    74221 tttgttcaag aaaacaatca ggtattttac accaacttgg cgtgacaata aaatgtgttc
    74281 acgtgtttga ggcatcggac cgtcagttgc agaaacaact aagattgcac catccatttg
    74341 tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt cctggtgcat caatatgcgc
    74401 gtagtggcgt ttttctgttt catattctac gtgtgcggta ttgatcgtaa tcccacgttc
    74461 acgttcttct ggagctgcat caatactagc atagtcttga ggatttgcta ggcctttttt
    74521 gcctaatact gtagtgatcg cagcagttaa agtagttttc ccatggtcaa cgtgtccaat
    74581 cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt tcttttgcca taatttacaa
    74641 acctcctaaa taatatagat cactgaaaaa tttcagctct caccttttta ttatagtctt
    74701 tttttgacta aatcaaaaag aatacgtccg acttactttt tgtaagattc gaactaagct
    74761 tattatacgt caatattggt caaagtcaac taagagcact cgtctgtctt atacgcgaaa
    74821 aaagtacctt ttataaataa aaaaatgtgt tttttgagaa aaacttcaag atagtcctta
    74881 actttctttt gaagcaataa gaacaaaatg aggaaaagtt taaaattcag ctgttgccaa
    74941 caactttcaa tagacgaaat cttctatttc gttaataata aggaaagagg tgaagtacat
    75001 gaaaaaatta attggcgtac ttgtcgtttt aggcatattt ctcggcggaa gttttgcagc
    75061 ttatcattat ttttacggcg gcgaagctta ttatacaaaa atcacgacga atggcgaaat
    75121 gtcagctacc caagcagata acggagagaa attcacgact tatacctaca agcaagcggc
    75181 ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc gaagaaagag aacatccatt
    75241 aaagatgaat gcgtatctta aactcaaagt caatcctcgt aaaggtgtat taagctggga
    75301 agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa aaaatcgata attagtaaat
    75361 ggtcttaaaa ttttattaga taaaaagagg ctgggacaga agcgtttaac tccaagaaat
    75421 aagaaggagt tgcttctgct tccgccgttt atacgtgttt agagcgtgag acaaaagtgt
    75481 tctttacttt tgtctcacgc tctttttttg ttatattcgt cttttccgat ccttctcttg
    75541 acacaattca tttaactgat cactggtact tgaacaccta atattctagt catttttata
    75601 aacgattcaa tacttcatcc acatttttga tcatcacgga tatcgtacca tccggattat
    75661 tcacaaattc aatcaaatct gggttgcgat atacatctac tggtacgatc agttcgatcc
    75721 cgtttgatag cttgaatttt tgttttccaa attttttctc agaaatttct tgtacttctt
    75781 ttacaggagg tgcttctggg acaaatcctt gctcttgtac ttcttcttta aaagccattt
    75841 ttgccgtgat gttttccttg aagacttttt ccgcaatcat ctcatgatcc aaccgacctt
    75901 tttcttctat cgtatcatag acagcttctt tcaaatcagc catgatatca aattcttctg
    75961 tctcaaattt ttttccaaga tgcttggcta ctttttggat cacttttaca ttttcttcta
    76021 aagaaggtgc aggaacactt tcgatcactc ttccagaaaa ataaagctct tttttgccag
    76081 aaaactcata ttttttttca attaattcgt aggtccaatc agtcaaattc acagcgaatg
    76141 cttcatctgc tttttgtgtt ttcgccccta gaattgctcg attcaaaatc aagcggttgt
    76201 cgatccctgc ttcgtctgct tcaacaaagt gagtgtaagc ctcacgataa ttgactttca
    76261 ataaagataa gtacatcact gtatctaatt catacaagac aacaaataca tctgcactag
    76321 gtgcttcttc actttcttgg tagatatcga accaccgctg aacgattgct tcacttgctt
    76381 ccacaaaatt ttcttgagcg attttaagtg attcaacgat catgctttct tctgctagtt
    76441 gtccagtttt tgtttgagca gaagagattt tttggatctt cttttgaaga aaatcacgaa
    76501 tatattcttt tgtcagatcc agctcttttt gtgaaaagac tggagaacca gtttctctgt
    76561 caataatatg cagaattgct ttttttaaat agatatccat tttctcattc ccttctgtct
    76621 tagtttacgg aaaaaaaatc aaaaatacca gaatcaaaat cattttcttt taaacaaaaa
    76681 tttcaagagt agaaacaaaa tggattcttt ttttcgaaaa atgcgctaca cttatagttg
    76741 aacgaataaa aaaggagctg aaagtatgaa ttcattaaca agcacttatc gtctatcaaa
    76801 tggttacgaa atcccggtag taggattcgg cacatggcaa acacctgatg gggatgtcgc
    76861 tgtttcctct gttaaagaag cgctggctgc aggttatcgc catatcgata ctgcccaagg
    76921 atacaagaat gaagaaagcg tcggccaagc gattaaggaa agtggaattc ctagagaaga
    76981 gatattcttg acaacaaaat tatggaatgc aaaccacagc tatgaacttg tgatgtcttc
    77041 ttttgaagaa tcattgaaga agctccaaac agattattta gatctgtttt tgatccactg
    77101 gccaaaccct gttgcttttc gtgataattg ggaacaagca aatgcagata catggcgagc
    77161 atttgaagaa ctgtatgaag caggtaaaat caaagcaatc ggtgtgagca atttcttacc
    77221 ccaccatcta gatacactag caaaaacagc aaaaattatg ccgatggtca atcaagtttt
    77281 ccttgcacca ggcgaattac agacaactgt agttgagtat gcaaaaaaac atgatatgat
    77341 cctcgaagca tatagtccat taggcactgg taaaatcttc gatgtgcctg aaatgaaaca
    77401 aatcgctgaa gcacatgaca agacgattgc acaagttgct ttgcgttggt cgctgcaaca
    77461 cgaattcctt cctcttccta agtcagtgac accaagcaga atcaaagaaa atactgaatt
    77521 atttgatttt gaattaacag aagaagaaat gaaacaaatc gatcagttag atggtgtagt
    77581 cggcaaagca aaagacccag atactaccca attttaagtc gaaaggtgat tttatggatc
    77641 caatcgaacg cttgaattct ctctcggaag aagttaccca gacttttcat tccgattttg
    77701 tctttttgat cgatgcagag aaaatccaac attttcctgc aagaaactgg acacatgatc
    77761 aaatcatcga agaactgaaa aaacggttcg atcattcgct aatggtcaaa ccctggcacg
    77821 aacatgaagt catttattca cctgaactac ctgtttttgc cttgataccg aaaaaataga
    77881 aagaatggaa cggattatgt atatatacat aatccgttcc attttttatt tttctttcaa
    77941 aaaacgggaa aatacgcaaa tttttctgtt gtaatttgcg tatacgcaag tttttttgca
    78001 ttactccttt tcatttggct gtttttttct tataatcgaa agggtatgag cgaaggagag
    78061 aacatatgaa gaaaaaacag aaacaaaaat tattaaatca attccgtcct tcattggatg
    78121 gtgtaagagg acaattattc cgttctctag aagaagagag cttgcgacgt tatggtttgc
    78181 cgttacaagt catgcttgat cccaaaaacc gtcaaatctt aacgatcgga ttagctggga
    78241 aaacaaatga agatacacgg atcaacgtgc caatcgatga caacttcaat actgtattaa
    78301 agagaattcg ttcaggagaa aacgggattt tcgaacgatt ccgtgacaat cttcttattg
    78361 aaatcgtgtc ttactggaat gatcaacgat tgaaaaacga tgaaccaact gcgcaagctg
    78421 ttgcgacacc agttacagaa gaaacagtca gtgtgccaga agaaaaaacg gaaaaaccaa
    78481 aagcggacac aactgaaaat acacgctcaa ctgatacgaa tgccgcttta agttttgctg
    78541 atttttcaaa agccgttgct gagtatccta aattttacac agaacaaaat gaacatgaag
    78601 tagttattaa tgaaaaaaat gctgatgaac ctcgtaaatt agcaactatt tctatgacta
    78661 ctgaaaatga gttcgttatc gaaaaagcac tcgaacggaa atacaaagtc aaattgactt
    78721 tgattccttt gatcgaacaa tttgcagcga cagcgattac tgatcgataa aaattctatt
    78781 tgtcataaaa ggctgggatt taaaatccca gcctttttag tcatataata atttctacag
    78841 caagtaaaaa gaaattcctt ctaacatcag gctcaaatat cagcttgacc tgtccaacaa
    78901 atcacctatg atcctacaat gttaggcgac ttctcttcta cctgaagata tcttggagtt
    78961 gcctgatttc ttaagatgcc taaccttaac tataaaaaat tctaataata aacatatttt
    79021 ctgatagaga aaaaagcggt tctataatat tttgtgttgg tggaaaatcg aaagcgattt
    79081 tctactaaca cttttttctt cgtttcaact caaaaagaga ctcacttttg gtaaaattta
    79141 gtcgac
//
LOCUS       DADVXK010000002        76807 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.002, whole genome shotgun sequence.
ACCESSION   DADVXK010000002 DADVXK010000000
VERSION     DADVXK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 76807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.002"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            56..1180
                     /locus_tag="KB909_000074"
     CDS             56..1180
                     /locus_tag="KB909_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6836141.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1407..2324
                     /locus_tag="KB909_000075"
     CDS             1407..2324
                     /locus_tag="KB909_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836142.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2317..3150
                     /locus_tag="KB909_000076"
     CDS             2317..3150
                     /locus_tag="KB909_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6836143.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3233..4351
                     /locus_tag="KB909_000077"
     CDS             3233..4351
                     /locus_tag="KB909_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6836144.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4345..6243
                     /locus_tag="KB909_000078"
     CDS             4345..6243
                     /locus_tag="KB909_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBB6836145.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            6237..7460
                     /locus_tag="KB909_000079"
     CDS             6237..7460
                     /locus_tag="KB909_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6836146.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7546..9480)
                     /locus_tag="KB909_000080"
     CDS             complement(7546..9480)
                     /locus_tag="KB909_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6836147.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9706..10362
                     /locus_tag="KB909_000081"
     CDS             9706..10362
                     /locus_tag="KB909_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6836148.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10436..10789)
                     /locus_tag="KB909_000082"
     CDS             complement(10436..10789)
                     /locus_tag="KB909_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6836149.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            10981..11910
                     /locus_tag="KB909_000083"
     CDS             10981..11910
                     /locus_tag="KB909_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBB6836150.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11921..12757
                     /locus_tag="KB909_000084"
     CDS             11921..12757
                     /locus_tag="KB909_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBB6836151.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13005..13781
                     /locus_tag="KB909_000085"
     CDS             13005..13781
                     /locus_tag="KB909_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6836152.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            13957..14700
                     /locus_tag="KB909_000086"
     CDS             13957..14700
                     /locus_tag="KB909_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836153.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14693..16273
                     /locus_tag="KB909_000087"
     CDS             14693..16273
                     /locus_tag="KB909_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBB6836154.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16524..17003)
                     /locus_tag="KB909_000088"
     CDS             complement(16524..17003)
                     /locus_tag="KB909_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6836155.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17019..17771)
                     /locus_tag="KB909_000089"
     CDS             complement(17019..17771)
                     /locus_tag="KB909_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6836156.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17888..17958
                     /locus_tag="KB909_000090"
     tRNA            17888..17958
                     /locus_tag="KB909_000090"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17920..17922,aa:Gly,seq:ccc)
     gene            18319..19044
                     /locus_tag="KB909_000091"
     CDS             18319..19044
                     /locus_tag="KB909_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBB6836157.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19299..19565
                     /locus_tag="KB909_000092"
     CDS             19299..19565
                     /locus_tag="KB909_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBB6836158.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19562..19993
                     /gene="ruvX"
                     /locus_tag="KB909_000093"
     CDS             19562..19993
                     /gene="ruvX"
                     /locus_tag="KB909_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBB6836159.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20018..20323
                     /locus_tag="KB909_000094"
     CDS             20018..20323
                     /locus_tag="KB909_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBB6836160.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20404..21549)
                     /locus_tag="KB909_000095"
     CDS             complement(20404..21549)
                     /locus_tag="KB909_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6836161.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21610..22257)
                     /locus_tag="KB909_000096"
     CDS             complement(21610..22257)
                     /locus_tag="KB909_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6836162.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22451..22744
                     /locus_tag="KB909_000097"
     CDS             22451..22744
                     /locus_tag="KB909_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836163.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22788..23099
                     /locus_tag="KB909_000098"
     CDS             22788..23099
                     /locus_tag="KB909_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836164.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23096..23720
                     /locus_tag="KB909_000099"
                     /pseudo
     CDS             23096..23720
                     /locus_tag="KB909_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23861..24019
                     /locus_tag="KB909_000100"
     CDS             23861..24019
                     /locus_tag="KB909_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836165.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24020..24382
                     /locus_tag="KB909_000101"
     CDS             24020..24382
                     /locus_tag="KB909_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836166.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24419..25267
                     /locus_tag="KB909_000102"
     CDS             24419..25267
                     /locus_tag="KB909_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBB6836167.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25257..26732
                     /locus_tag="KB909_000103"
     CDS             25257..26732
                     /locus_tag="KB909_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBB6836168.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            26998..27405
                     /locus_tag="KB909_000104"
     CDS             26998..27405
                     /locus_tag="KB909_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBB6836169.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27408..27623
                     /locus_tag="KB909_000105"
     CDS             27408..27623
                     /locus_tag="KB909_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836170.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27627..28007
                     /locus_tag="KB909_000106"
     CDS             27627..28007
                     /locus_tag="KB909_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6836171.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28141..28296
                     /locus_tag="KB909_000107"
     CDS             28141..28296
                     /locus_tag="KB909_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBB6836172.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28365..28838
                     /locus_tag="KB909_000108"
     CDS             28365..28838
                     /locus_tag="KB909_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6836173.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28835..30529
                     /locus_tag="KB909_000109"
     CDS             28835..30529
                     /locus_tag="KB909_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6836174.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30495..30680
                     /locus_tag="KB909_000110"
     CDS             30495..30680
                     /locus_tag="KB909_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836175.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30684..31859
                     /locus_tag="KB909_000111"
     CDS             30684..31859
                     /locus_tag="KB909_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6836176.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31852..33375
                     /locus_tag="KB909_000112"
     CDS             31852..33375
                     /locus_tag="KB909_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6836177.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33431..33715
                     /locus_tag="KB909_000113"
     CDS             33431..33715
                     /locus_tag="KB909_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6836178.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33702..34037
                     /locus_tag="KB909_000114"
     CDS             33702..34037
                     /locus_tag="KB909_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6836179.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34332..34958
                     /locus_tag="KB909_000115"
     CDS             34332..34958
                     /locus_tag="KB909_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836180.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35700..36536
                     /locus_tag="KB909_000116"
     CDS             35700..36536
                     /locus_tag="KB909_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBB6836181.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36600..37031
                     /locus_tag="KB909_000117"
     CDS             36600..37031
                     /locus_tag="KB909_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836182.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(37093..38415)
                     /locus_tag="KB909_000118"
     CDS             complement(37093..38415)
                     /locus_tag="KB909_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBB6836183.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38569..40209)
                     /locus_tag="KB909_000119"
     CDS             complement(38569..40209)
                     /locus_tag="KB909_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBB6836184.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40542..41012
                     /locus_tag="KB909_000120"
     CDS             40542..41012
                     /locus_tag="KB909_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBB6836185.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            41234..42337
                     /locus_tag="KB909_000121"
     CDS             41234..42337
                     /locus_tag="KB909_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6836186.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            42621..43301
                     /locus_tag="KB909_000122"
     CDS             42621..43301
                     /locus_tag="KB909_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6836187.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43391..44425
                     /locus_tag="KB909_000123"
     CDS             43391..44425
                     /locus_tag="KB909_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6836188.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44439..44774
                     /locus_tag="KB909_000124"
     CDS             44439..44774
                     /locus_tag="KB909_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836189.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            44758..47238
                     /locus_tag="KB909_000125"
     CDS             44758..47238
                     /locus_tag="KB909_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836190.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            47294..48853
                     /locus_tag="KB909_000126"
     CDS             47294..48853
                     /locus_tag="KB909_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836191.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            48850..50214
                     /locus_tag="KB909_000127"
     CDS             48850..50214
                     /locus_tag="KB909_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6836192.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50385..51455
                     /locus_tag="KB909_000128"
     CDS             50385..51455
                     /locus_tag="KB909_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836193.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51470..52138
                     /locus_tag="KB909_000129"
     CDS             51470..52138
                     /locus_tag="KB909_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836194.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52158..52736
                     /locus_tag="KB909_000130"
     CDS             52158..52736
                     /locus_tag="KB909_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6836195.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53137..54048
                     /locus_tag="KB909_000131"
     CDS             53137..54048
                     /locus_tag="KB909_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6836196.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54136..55053)
                     /locus_tag="KB909_000132"
     CDS             complement(54136..55053)
                     /locus_tag="KB909_000132"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBB6836197.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55255..55692
                     /gene="zapA"
                     /locus_tag="KB909_000133"
     CDS             55255..55692
                     /gene="zapA"
                     /locus_tag="KB909_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBB6836198.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            55751..56299
                     /locus_tag="KB909_000134"
     CDS             55751..56299
                     /locus_tag="KB909_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBB6836199.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            56414..58774
                     /locus_tag="KB909_000135"
     CDS             56414..58774
                     /locus_tag="KB909_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBB6836200.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            58861..59175
                     /gene="trxA"
                     /locus_tag="KB909_000136"
     CDS             58861..59175
                     /gene="trxA"
                     /locus_tag="KB909_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBB6836201.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59357..61135
                     /gene="uvrC"
                     /locus_tag="KB909_000137"
     CDS             59357..61135
                     /gene="uvrC"
                     /locus_tag="KB909_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBB6836202.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61280..62179
                     /locus_tag="KB909_000138"
     CDS             61280..62179
                     /locus_tag="KB909_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836203.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62172..63434
                     /locus_tag="KB909_000139"
     CDS             62172..63434
                     /locus_tag="KB909_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836204.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            63595..65493
                     /locus_tag="KB909_000140"
     CDS             63595..65493
                     /locus_tag="KB909_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBB6836205.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(65823..66542)
                     /locus_tag="KB909_000141"
     CDS             complement(65823..66542)
                     /locus_tag="KB909_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBB6836206.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            66879..67211
                     /locus_tag="KB909_000142"
     CDS             66879..67211
                     /locus_tag="KB909_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836207.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67198..69201
                     /locus_tag="KB909_000143"
     CDS             67198..69201
                     /locus_tag="KB909_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBB6836208.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69220..69690
                     /locus_tag="KB909_000144"
     CDS             69220..69690
                     /locus_tag="KB909_000144"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBB6836209.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            69711..70295
                     /locus_tag="KB909_000145"
     CDS             69711..70295
                     /locus_tag="KB909_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBB6836210.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70310..71296
                     /locus_tag="KB909_000146"
     CDS             70310..71296
                     /locus_tag="KB909_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBB6836211.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            71286..71597
                     /locus_tag="KB909_000147"
     CDS             71286..71597
                     /locus_tag="KB909_000147"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBB6836212.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            71619..73400
                     /locus_tag="KB909_000148"
     CDS             71619..73400
                     /locus_tag="KB909_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBB6836213.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73393..74769
                     /locus_tag="KB909_000149"
     CDS             73393..74769
                     /locus_tag="KB909_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBB6836214.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            74776..75411
                     /locus_tag="KB909_000150"
     CDS             74776..75411
                     /locus_tag="KB909_000150"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBB6836215.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            75441..76796
                     /locus_tag="KB909_000151"
     CDS             75441..76796
                     /locus_tag="KB909_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBB6836216.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
BASE COUNT        25437 a        12980 c        15963 g        22427 t
ORIGIN      
        1 tatacataag tgaaagcgtt ttatataaga acttgaaaag aaagaaggga tagacatgaa
       61 aaaaagatac aaattggtga tagctttgct aaacattacc ctattattca gcttaagtgc
      121 atgtggaaaa actaacgaag aagtaacagc aaacatcgca gatccaatga taaaaaaagc
      181 cactacatta gaagtatatg tcgcaaacgg caaactgaca aactatgttg aaaatgctgc
      241 aaaaatctat aaccgcaaaa ctggagcaaa tattgactta aaaattgtga atgtagcttc
      301 gggaacagca acagtacaaa tgatcacccc aaaattggta acacacgaag atatgccgga
      361 tattatctcc atggcagaca cttcagcagc aggtgtgctg gaaaaatttc aagatgcttt
      421 ttatagtgct gatgaatatg gattttatga caaatatggc gatcagtttt atgatcaaaa
      481 attgaatatt ttgcgtcaac aaacgagtaa tgaaacgatt attccttggg ctagtgattt
      541 taccccagca ctttgttatt atcaaccaaa aaaatttgct gaaataggtg tagattttga
      601 agaaatcagt tcttgggaag aatatatcca ggtggcaaaa gcattaaaag aaaaaactgg
      661 tagttttgga attgccttgc cagaatctgg ggaccaagaa ttgtttatca acatgctagc
      721 ccagcagaat caatctttgc ttgatgaaga aggaaatatc cgtctgaata ctaaagaagc
      781 gaaacatgct gcaaagttaa tcaaagaaat gatcgactca gatattgtac atttctacgg
      841 tgcacaagat gctgagaaag catttcaaga atctgcaatg tttgttgctg gcggctggta
      901 tgctacgaat atgtctttga attttcctga tgcatctgac aaatggcgca tggctccact
      961 gattcctttt tcaaaagaaa atccaggaaa aggtgcagta tcaggaggat caagttttta
     1021 tgtccctaaa gatgcaaaaa atccacaagt ggcacaacaa tttcttacat ttatgctgac
     1081 agatgaagaa tgcttagcca acgcactgga gctgggcgtg gctacatcta actcattggc
     1141 ctatcaaaca gaagcagctg agaaaaagtt tgactactaa ggaggacaaa aatactatga
     1201 actattgaat aaaatcaatg aaaatacatc aaatactgtt ttaccagcca cttattcaga
     1261 tgctacgtct tatttgacta ccgctgcata taactattgg caaacaggtg attttgaaaa
     1321 ttcatatcta aaagaagcag aaaattttgc tcataagtac ggcgtaaaat taactggtga
     1381 ttaaaaaata ttaggaggac ttaacgatga tgcaatcttc gttaccaagc aagacaataa
     1441 agaacagcaa gaaaaaagca acagatacgt ctcataaaaa aagtgcttat ggattggtca
     1501 caccttttgt tattttcttt attgtgacga ttttgattcc catcattatc tcgtttgctt
     1561 ttagttttat gaaaattggc tactcatttg aatttgttgg atttgacaat tatctagcta
     1621 tcttccgaga tccattgttt attaaatctt acacgaatgt tttgattatc atggcaggat
     1681 caattccaat aacgatgcta ttagctattt actttgctgt tttattgaat tcagcacagt
     1741 taaaaggaaa aggatttttt agaactgtct attatattcc aaccattaca tcaacggtgg
     1801 ctgtagcttc cgtattcatg acttttttca atccgactgg gttattcaat ggatttttga
     1861 atgcgctagg aattaacggt gtacagtggt taacaaatcc tttttggata cgaatatcaa
     1921 tgatcatcac gatgatttgg cttagtgtag gatataacac tattttattt ttagctggtc
     1981 ttcaagggat ttctaaagag atatacgaaa gtgctgaaat agatggagca tcgaaatttc
     2041 ggcaattctt tttattaacg atccccatgc taaagccaat cattttaatg gccacagttt
     2101 tagccactat caatggcttg ggtaatttca atatcccaaa tatattcttt gggacttcca
     2161 atggaccaga aaattcagct ttggtcgtag gagtcaattt atataaaaca agttttgaaa
     2221 tggttgattt tggaaaagcc tctgctattg cctggacgat ggtgtttgta tctgttatat
     2281 tatcggctat tcaatttaaa ttcggaggtg ataaaaatga ctaaacaaaa gatacaaagc
     2341 agaattttta cgtacgtcat tattgtgttt ggtgccttaa tatttttgat gccatattta
     2401 tatatgattg tagcttcaac gcaaagtaat caagaaattt taagtggcgg aatcaatttc
     2461 aagtttgggg atatgctatt aaaaaactgg caagccatca tggcgagata taattatccc
     2521 ttgattattt ggaattcgat tgttattgct gtaatcagta cagttttagc tacagccagt
     2581 tctacaatgg cgggttatgc attagcaaag tatcgtttta tggggaataa actgttgttc
     2641 aatacagtta tgctatctag gatggtgcct ttttttacca cattgattcc tttattttac
     2701 attatgagtc gtttaggatt atcgaatact tatgcaggtg tgatcatccc ttcgattgcc
     2761 agtacaactt cagtgtttat gatgcgacaa tatagcagtc aatttcctac agcactgatg
     2821 gaggctgcca gaatcgatgg tgccaatgag tgggtgattt ttacgaaaat cgctgtaccg
     2881 attttatcac ctacgattat tactagtggt ttacttatct ttatgggaag ttggaatcaa
     2941 tatctatttc cattagtcat gctttcagat aaagataaat atacggttcc cttaattatc
     3001 aaaaatatga cggtttctag tacaggtgag ccaattaatt atggcgcaat tatgctaatt
     3061 ttagcaactt cagtgatccc aatggtcttg atttatgtgt gggcgcagtc taaatttaag
     3121 gagaatgaca ttggagctgc aaataagtaa aaaaaataac gaatgttaac catctagttc
     3181 gttctaggag caactccaca ttcataaaaa ttaaaagaat ggcgggatat ccatgaatga
     3241 acagacgaag gaatggtcaa gaaaaatttt gaatgtagct tctgaaaaga tagatgcgga
     3301 attagacaga atggggaata aaattccata tatttcttac aacggaaaat atacagacgt
     3361 aataaaggac agaggaatcg actggtggac caatggtttt tggagtggta ttttatggca
     3421 gctctttcac aagacaaaac gagaaaagtt caaagaggca gcaatacaac aagaacaatt
     3481 attagaatct gccctgtacc atttttcaga cgttcatcat gatgtaggtt ttttattctt
     3541 accatcggct attgcacatt atcaacagtc tcaaaacaaa catagtcgac aactagggtt
     3601 acatgcagct acggtacttg ctggacgcta taatatttca gggaactatt tagtagcatg
     3661 gaatgaccat aaacctggtt ggatgattat tgatagtatg atgaatttac cattactgta
     3721 ttgggcttcg agggaaactg gtgatccgag gttctctaaa attgctcggc agcatgcaga
     3781 tacaacagct aagtatctag tgaggaaaga tggatcaacc gggcatatcg cagaatttga
     3841 tgcagaatca gggaaatata ttcggttact tggcgggcaa ggatacaatg agaattcttg
     3901 ttggagcaga ggaaatgcat gggctttata tggattcgcg ttaagttatc gttacacaaa
     3961 aaatccgtac tatctagcta tagcagaaaa gatagcagta aattttattc agaaaatcga
     4021 aaaaactggt tatattcctc tcattgattt tgctgtaaaa gattcgaata ttgataccag
     4081 tgctggagta tgcgctgcat gcggtcttct ggaattagca ggatatgttt cctctgtacg
     4141 atcaaaaatg tatcatgaag ctgctatcaa tatactccaa aagacagaaa agcactatgc
     4201 aaattggaat atggatgaag atgggatcat tggaggcgga gcagaagcat accatagaga
     4261 actgacttat aatgtgccac tgatctattc tgattatttt tttattgaag gcttacttcg
     4321 attagaacag tcggaattag ctatttggta gtaaaaagag gagaaaatac aatgaaacat
     4381 ccagtaccac tattaaggac cagacaggat tactttgact tatttaaaaa gataaatcaa
     4441 ccactccagc cgttttatcg agcaagtggc gcacaaattg attatataca tcaaggggta
     4501 ggatatggaa ataaaattgc aggaatggaa ggattctctc gggttttatg gggagcgggg
     4561 cccgcaattg accaattaga tgaacgatgg ttgaaattaa ttctatcagg aataaaagct
     4621 ggaacagatc cttcccatcc cgattattgg ggagaaatac atgaaagaga ccagcgtatg
     4681 gtagaaatgc ccgcaatgtt attagcgtta tatcatcatg aacaattatt atggaaaaaa
     4741 ttagatacag gagaaaaaag ccagattatt cattggttct cgcaaatttt tgaatatgaa
     4801 tgtgcagatg gtaattggca attttttaag ataattgtcg gaacaattat ccaaaaattt
     4861 ggttatccag ttaaagaatc agcactgaaa gaagcatttg ataatataga aaattgttat
     4921 cttcaaaatg gctggtatcg agacagttca agaggtcgcc aagattatta taatcctttt
     4981 gcatttcatt attatggttt gatttatagc gtactagaac cagaaaagcc cattagccag
     5041 atatataaga accgagctat tgatttttct agagactata ttcatttttt tgcggaagat
     5101 ggtgcaaatg tgccttttgg tcgaagcatg atttatcgtt ttgcagtttc aagcttttgg
     5161 tcagctatgt tgtgggccga tcttttgcct tttaaattag gtgaaatcaa ggggttagtc
     5221 aatcggaata taagatggtg gatgcaaaaa gaaatatttg atgaaaaagg tatcctgaat
     5281 attggttata cctaccctca attgacattg actgaaccct ataatagtac gttatctcca
     5341 ttatggctga ataagatttt tttattgttg gcgctacctg aagaccatga gtattggacg
     5401 gctaaagaaa tgcctatgcc tattcgtgaa ggaactaaac ttctttcaga agccaatttg
     5461 ctcatacaac atgataatgg acatacattt tttttgaatg cgggacaatt agggccaaat
     5521 ttccatacat tgaccaatga aaaatattta aaatttgctt attctagtca atttggtttt
     5581 tcgataccgc gagcgaatca attgaaagca gaaatggcaa tggattcaat gctagggatt
     5641 cagcgagcgg acacatatat cacgaccagt tttaagaatg agagcatcaa aacctatgga
     5701 cagttcatcg ttcgaaataa tgtacgagac attgtatgta agaaagaggt acttgcctct
     5761 acatgggaac ctactttaca ggcaaaaatc agaacttggc ttattccttt tgaaggctgg
     5821 cagattcgcg tacacaaagt agaattagat acagaatatg ttctatatga gacagggttt
     5881 gctattgaat gttctcctga gaaagaagga ataatcatag aagaagacaa ggaaaactat
     5941 agggtgagtg aagctggctt ttcaggtatt atctgtttaa gtgacgatac tattaaacga
     6001 aaatccacag ctattatggg tttgcccaat acaaacttga tgacatggga aaacactttt
     6061 attcctggat tagagggtac atttggaaaa ggaacccatt ggctcggaac aggagtggtt
     6121 gctcatcaag atcgggatta tagtttagaa gtatggaaca atcgtcccaa aattgatttt
     6181 gatgggacaa ccgggctaac tatccaaaat aaaaacaata aaaaaagact aaaattatgc
     6241 taaaggctgg tggggaaatg cttgataaag tgatgtttga agagataata catccagaaa
     6301 aatggataaa tgaatgttat aaagaattaa tggaaaaaga atggaataat gagatcgagc
     6361 gttgtcgcag acacacggag aggttaatca aacgtatcag taacagtcag tatcaattcc
     6421 caagcgagtg tcctataaaa ggacgttatc cattaagaga caatattggt tggacagaag
     6481 gattttggac aggaattaat tggttgttat ttgagaagac gggtgatcct ttatttcaac
     6541 aaacagctga aaaagcagat atagatttta tccacaggat tgactgtcaa attatcacta
     6601 atcatcacga tcttggtttt ttgtattctt tatcaaccgt agcagattat aaaataacgg
     6661 gaaatcgaaa aatgaaggaa gcttcaattg atgctgcaga aacattactt cagcgttttt
     6721 gggagaaggc aggagttata caagcttggg gagatcctag tgatccttca caacaaggta
     6781 gaatgatcat ggattgttgc atgaatcttc cattattgta ttgggcgagt gaagaaactg
     6841 gaaatcaaaa atataaaaaa gctgctcagg ctcatattca aaatgcagca gattatttag
     6901 taagagaaga tggttcaact tatcatacat tttatatgga tgtcaaagat ggaaaaccaa
     6961 gatatggaag tacgcatcaa ggttatagtg ataattcctg ttgggctaga ggccaagcat
     7021 gggggattta cggttttgca ttaagttatc gttatttgaa agaacaaaaa tattttgatt
     7081 taagcaaaat attagccaat tattttatga atcggttgcc agaagatacc atttgttatt
     7141 gggatttgat ctttgatgat tctagcagag aagaaaaaga tacatctagt atggtgatca
     7201 tggtttgtgg attattagaa ttaatagaat caggtctatt agacaaaaca gaaaagaact
     7261 tataccagtc tgctgtttgg aaaattatgc gacaattgaa agaaagatat gctacaacgg
     7321 aagaagaaga tggcttttta acacagtctg tttataataa gcccaaaaat aatggggtaa
     7381 atacaccttg tatttggggt gattactatt atttagaagc tttagtgaga atgactagta
     7441 attggtcttc ttattggtga aaaaggtaaa tatggaattt ttgtttgata aaataaaaaa
     7501 agaaaaacca aaacagcatg aatggtttct gttttggttt tttcgttaat tttcatattc
     7561 ttctaattcc aagcttagtt cttcccattc cgtcaatttt gtttcttgat cttgtctagc
     7621 agcttctaaa tcttggttca gctcattgag ttttacgtga tcttccaggt tttctggcgc
     7681 gaccatttct tgttccaact gatcgatcca ttcatcgatc cgcgccattt cttcttcaac
     7741 ctgagtaatt tttcgttgaa ggctacggat aagcttttgc tgttctttgc tttggtaata
     7801 atcagatttg ttcgtgggag caggagcaga ttctggctca tcttgtgcca acaattcggc
     7861 gatttcttct tcttcctgct ttttctctaa ataataatca tagtctccta gatagacttt
     7921 gctgccattt tcagagagtt cgacgacttt tgtcgcgatc cgattgatga aatatcggtc
     7981 atgggaaaca aaaagcagtg tgccgtcata atcgatcaat gcattttcta atacttcttt
     8041 gttgtcaata tctaaatggt ttgttggttc atccaaaatc aaaaaatttt ctttgttcat
     8101 cgctaacttg gctaaagcaa cccgtgcttt ttcaccgcca cttagcagag ggattggttt
     8161 ttctacatct tcgccagaaa ataagaaagc acctaaagca cttcggatct ctttttctgg
     8221 agtggtagga tgctcatccc acaattctgc taggatcgtc ttgtttgtat gcagatcagc
     8281 ttgaccttga tcgtaatagc cgatggtgac atttgtccct agcgtttctt ttccacggat
     8341 aaaagggatc tggtgaatga ttgatttcag caacgtcgat ttcccgatac cattcggacc
     8401 tactagagca atcgcttctt gacgacggat atctagattg attggttcag ataaggtgac
     8461 attatcatat ccgatagcgg catcttcgat ttgcaagact acatttccag aaggcttttc
     8521 tatactgaat agaaagtttg cttgtttttc atccccttga ggacgatcca gccggtccat
     8581 tttttctaat gtctttctgc ggctttgcgc tcgttttgtg gtagaggcgc gaacaaggtt
     8641 ccgagcaacg aagtcttcta atttatggat ttctgtttgc tgcttttcat aagccttcca
     8701 ttcacttgct aactgttctg ctttcaaatc tagatatttc gaatagttac ctttgtaatg
     8761 gcgcattttt cttctgctta attcatagac ttcattgact actttatcta aaaaataacg
     8821 gtcatgggaa acaatcaata atgcaccagt atagctttgc agataattct caagccagga
     8881 aagtgtctcg atatctaaat ggttcgttgg ttcatctaga atcaaaatgt cagggtgttg
     8941 caaaagcatg cgagctaaag ctaaacgtgt gcgctgtccg cctgataaag tatcgatttt
     9001 ctgatcataa aatgaagaat cgaatttaaa cccatgcaat acggaacgaa tttcattttc
     9061 ataaccatag ccgtttcgat ctgaaaaatc gtgttgcagc cggtcgtatt cttttaaata
     9121 agaactataa gcaggtgtgt ctggcgtacc ttcgctaatg aaaatctcta gctcgcgcat
     9181 ccgctcttcc atttgtctaa cttgttcaaa agctttcagc atctcgttcc aaactgtttc
     9241 attggaatca agtcctgtgt cctgagcgag gtatccgaga gtcgctgttt tatttttagc
     9301 gatctttcct tcatcaggtg cttcaattcc agcaatgatc tttaataaag tcgattttcc
     9361 agcgccattt ctgccaacta aagcgacacg agcgcctgta ctgatttcta aatgtatgtt
     9421 ttcaaataag acttctgcac caaaatggcg agcaatctga ttggcttgta ataatatcat
     9481 ggaatcctct tttctacttt gtgaattctc ctcaaataaa aaactatttt tcaattagta
     9541 gtctaccata aattccatta tactgcgaga tttgcagaaa tgataaataa atgaataaag
     9601 aataaaattt cacaatatct gagcaatgga attgattttt tcctataaat actgctatga
     9661 tggagaaatc aaagatgtaa ttagacaata cgtggaggtc atttcgtgaa agatcatatt
     9721 attccaaagg cgacagctaa aagactgcct ttgtattatc gctatttaag gattttaaat
     9781 aatgctggaa agaaaaaagt gtcttcaact gaattaagtg aagccgttca agtagatagt
     9841 gcaacgatcc gtcgagattt ttcttatttt ggcgaattag gaaaacgtgg gtatggttat
     9901 gatgtagaag atcttatgca cttttttgca aagacattaa acgacgatca attgacaaat
     9961 gttgcgctga tcggtgtagg gaacttggga agtgctttac taaaatacaa attccatcaa
    10021 agtaatagca tacgtatcag ttgtgctttt gatgtgaatg aggaaatcgt tgggcgcatc
    10081 gtagacggta tccccgttta tccaatggaa gatatgtcag aacaaatcaa gatccaacaa
    10141 atcgaagtag caattttaac gatacccgct gaaagagcac aagaagtagt caatcagtta
    10201 acggaagcag gaatcaaagg aatcttgaac tttaccgctg ctcgattgaa tgctccgtca
    10261 gatgtattga tccaaaatgt tgatttgacg aatgaattgc aaaccttgat ctatttcttg
    10321 cattctgacg caaatgcgca ttccgaaaat acagcagaat aaaaataaaa agcgattgaa
    10381 caaatgaagg caaaactttc acttgttcaa tcgctttttt ctgtttggac aacgattatt
    10441 ttgttcggaa gatttcttca taagaaaggg aatcatcttc tgctgtcagt tcatctagta
    10501 gataacggat ttttttaaag tcgatgaacc gtgcttgccg aaagacttct tttccttgat
    10561 gaaaaatcag gacaactggc gcagtcagca cttcaaattt actagctact tctggtgttt
    10621 caaatgcatc caaatgaagt gccggaatat cataatgtgt gagaagttcc tctagtcgtg
    10681 gacgaacagc gtgacaaaca ctgcaattag gcatcgaaag ataaatgacg gcaacggatg
    10741 actgttgcag tatgtcttga acttcagtca agttagtggt ttgtttcatt tttattctcc
    10801 cttttatgat agaagtgata tgtatgagac cttaatttaa tgggaataac agaaaaagtc
    10861 aattgaagtg ctttggtaaa aaataagagt tgtgtaaaaa tttacagagc aacttgtttt
    10921 ttttgaataa aagcgtatat ttgcaaagcg aatgaactag aaataaaaag gaggaaactc
    10981 atgttttctt ttattccaaa ttcggttttg cagatgagta cgattttctt atcgatcgtt
    11041 attgaagcat tacctttcgt attattaggc tgtcttatct caggcgcctt acaagtattt
    11101 ttgaccccag aacgtgtgaa gagatggctt cctgaaaatc gtatcttctc tatttttact
    11161 ggttcgatct taggattttt ctttccttca tgtgaatgcg gcatcgtacc gatcgttcat
    11221 caatttgtta aaaaaggcgt accagttcac acagcgtttg cttttatgct gactgctccg
    11281 atcatcaatc caatcgtgat tttttccact tttatcgcat ttggcaattc ttggcagatg
    11341 gcaagctggc gggtgatagg cagctttttt gttgcccttg tgattggtgt ctggcttgcc
    11401 tattttcaaa aagacgctgt attgaaagaa aaaatcacgt ctaaagtagc agaaaatcac
    11461 catcatcatg tccatgaaga agaacaaagt gagaagaatg aaccaaaaaa tcagctgatc
    11521 catcaaactg ggcatgtgtt gacacattca atcgacgaat tttttgatac aggtcgttat
    11581 ttgatcattg gcggattaat cgcagctgcg atgcagactt atttaccaac tagaattatg
    11641 ctaacgctcg gctcaacaaa gattttagcc attatcatca tgctgttatt ggcctttacg
    11701 atgtctcttt gctcagaagc agatgcgttt ataggatctt ctttgttaag tctgttcggc
    11761 acagcacctg tagctgcctt tttggtcttt ggcccaatgg tcgatatcaa aaatctactg
    11821 atgatgaaac gatattttac aggacgcttt attttatcgc tgatcggact gattgccctt
    11881 agcgttattg gattcacatt atttatttag gagggaaaat atgctgcggt ttttgatttt
    11941 atctgggtat ttcgaattga tgatgtactt gcaagtttct ggcaaactcg atcaatatat
    12001 caatgtccat tatcgctact tagctattct ttcaatgatt ttatctgctc ttttggcttt
    12061 agttcagctg tatttgtggg tcaaaaacgg aaaagcagaa gaaaaggcac acgagcacga
    12121 tcatgaccat gggttgtcaa aaccttatca acgtggaatc gcttatgtac tgctagcttt
    12181 gccagtaatc gtggggacgt tgtttccaac agttagtctc gacactacga tcgtagaagc
    12241 caaaggattt aatttcccag taagtaaaga atcagtaggg gatccggaga tgcagacaca
    12301 atacttaaag ccggatacca gtatttattt caacaaatca gactacttag accaaatgaa
    12361 tgagttgaaa gaaaagtatg gggataagca aactatcaag atcacagatg aaaactattt
    12421 agaagttatg gagctaattt ataattaccc tagcgaattc attggcaaaa aaatcagcta
    12481 tgaaggattt gtttaccaaa caccgaacga tagcaataca gatatcttct tgttccgatt
    12541 cggcattatc cattgtgtgg cagattcagg agtctttggt ttgttgacgc atatgccgga
    12601 aggagtaacg gttaaaaatg atgaatggta taaaatagaa ggaaccatcc aatcagacta
    12661 ttatcaacca ttcaagcgtg aaatcccatc tgtagttgtt acaaacgctg agaaagtctc
    12721 tgctccgaaa aatcagtatg tgtatcgttc tttttaaaag aacaaaataa ataaacatag
    12781 ctcagacagc tgacacgcaa ggacgtcggt tgtctggctt tttttgcatg atgtattcat
    12841 ttgtttgata tttattttag aagcagcatc ctgaaagtat ttgatatcgg tttcaaaggt
    12901 gttggaaaag attgtgaaga gaattacaat ttattcctaa catgtatgtt gaaaagttgt
    12961 atgaaatgat tttgatagta aaatatcgag tggaggtact ttttatggta acgcgtatat
    13021 ttattttgga tgatagtttg gtttttgaaa aaatgctagt agaaattttg gaagaatcca
    13081 gaattttatt aagtccttgg aaatttgaga tcgttcaggg attgaacgtt atacaatttg
    13141 ttgaattcat taaaaataat gaaatctatt cctcagatat ttttttccta gacatcgatt
    13201 tgaacgccta ttatagcggt atcgaactag gcgaaatgct tagagaaaag aatgaaaagt
    13261 gtaaaattgt ttatctaacg tctcatccga ataaagcaat aactgttatt aatcgaaaga
    13321 ttacgcctag tggttatttg ataaaagaat tcacttatga aaaaaataaa aaaagcatcc
    13381 aaagttactt attgaaagaa aaagaaaact atcctgttca acatgctacg aaaaaaaggt
    13441 ggacaactgt ccgttatggt aatagcgatc actatatcca ttacgatgaa atcctttatc
    13501 taatgagcat gccaggttat aaaaataaaa taggcctagt attgaaagat gaagagattc
    13561 tcgtaaacgg cacaattaaa aaatataaaa aatcactcga atatgagtat ttatgtaaag
    13621 atttaaaagc ttatatcatt aatactgaaa acattacatc tattagcaga gtaaacgaaa
    13681 tagtaacatt tgcaaatgga gaacaactag agatgggaaa gagaagtatt gataaactaa
    13741 agaattttat gcaagaaaag atagaaaatg aatcatttta aagaaaacaa agactcatat
    13801 cttacctgtt agaagagtgt tttcctgtag aagagaacaa cccaagtagc agcctagtcg
    13861 tttctatcct tttttgttat gcactctttt tgacatttac tccaccaata acgaagggta
    13921 caataaaaag taataacaaa caaaaggagt acagaaatga ttgaattcat caatgtaagt
    13981 aaaagttacg ggaaaaaaca agcattaaaa gacttgtctc tctcgataag acaaggggaa
    14041 atttttggat ttttaggaca taatggtgcc ggaaaatcaa ctacgattaa aagtttagtt
    14101 agtattattg aaccatcatc gggaacgatt ttagtagatg gaatgaaatt gacggaaaat
    14161 cgattgagta tcaaacaaaa aatcggttat gtgcctgatt ccccagatat ttttttacaa
    14221 ttgacggctg gagaatattg ggacttgatt tcagctgcct atgaattaga cacacaaaaa
    14281 aaagaaaagc gtttagcaga attgacagcg ctttttgata tgtatagtca tcaaaatgaa
    14341 acaatcgcaa gtttttcaca tggaatgcgt caaaaaacga ttttgatcgg cacgttgctg
    14401 ccagatccag atatttgggt attggatgaa cctttgcaag gacttgatcc tcaagcagca
    14461 tttgatttga aagaaatgat gaaggctcat gccgcaaaag gaaaaacagt cattttttct
    14521 acacatgtat tggataccgc acaacagtta tgcgataaac tggctatttt gaagaaaggt
    14581 gaattgattt atcagggggc agttagtgaa ttattgaatg gctcacctga tgaaacgcta
    14641 gaaaagattt atttgaaaat ggctggaagg caagcgacag gagatggacc gtatgtataa
    14701 gcgacaatta ttagaattaa ttcgagttaa tcttttatat gttaatccac agctcacgaa
    14761 taaagcaaga gagaaaggaa aaaagggaaa gcgattaact atctatcttt tgtctcaaaa
    14821 tcttttttca gggctgattt ttttactgat ttacggattt gctatgtttg ctatgaactt
    14881 tgttaaattg ccaggtttct ttacttatta cgtggcactt tttggtatgt taggtttaac
    14941 tcaaagtata tcagtcattt ataatatctt ttttgaagga aatgacctgc aagtattttt
    15001 gcctctgcct tttggacaag aacaggtttt ttcagcaaag attttggtag ttgctttgac
    15061 catcattcct tttgtttttc cgcttctagt catgtttatt ttaaccggat ggcgagctga
    15121 tctagggatt ttgcttacta tcattatctc aatccttttg ttttctctat ttttgattat
    15181 tcttttttgt ctggctagtt tgattgtttt tggtttggct cgaacagcag tgtttaaaaa
    15241 acatagaaaa acagtttcta gtatcttgct tggcagctcg atgctgatcg catttgctgg
    15301 aatcatgtgg atgaatcatc aaacggggac tattgaaaat gagttaacag atcggcatcc
    15361 gatttcgata ttattgccat tctatgatgc tgccagtcag ccactttctc aacaaggttt
    15421 attgggttgg ggaatactag ctatcacggc tctgggattt ttccttgctg taaaacagct
    15481 gatagtacca aagcttacag agcaactgac tgattcaaac agtgagttca aaataaaaag
    15541 aacccataaa aagaaccaaa atgtgcatca gcttttattt agttacaatg ctcaattagt
    15601 aaaagaacct aatttgatta tgcaagttct ttcttcttcc ttgttaactc caatcatttt
    15661 tattcttgct tttgccctag gaggcgaaat aaaattaact gatttagata ataagttaat
    15721 cggtgttgtt ttcctggtag ggatcgcatt ggctttctta acagttaatc agacttcttt
    15781 tatcagcaat cttatttctt tggatcaaga aaattttctg tttatccgtt ctttgccaat
    15841 ctctatgaac caatatttaa aagaaaagtt cagattcgga tggatattgc agagtttttt
    15901 aactggtggg atcgcattat taagcggact gtcttttcag ctgcctttgt tttttatccc
    15961 tagcttgcta tttggttctt tattcggctg ctacttattg tcactacgtt atttcgctag
    16021 agattatcgg ttgctgctgc tgaactggac caatattaac caattattta acagaggttc
    16081 aggaagtttg ggtttagtcg caactatgat gggttcattg atcatcagta ttattcttat
    16141 cgtcttatac ggaatgttgg ctttgtttta tccattttgg ttagtgaata ttcctgtgat
    16201 cggtttagtt ctaatacttt ccgctctatg gatcgtttat tatcaacgaa cgttttggaa
    16261 aaaatttgaa taaagaagag gggccgtgac aaaaatcatg tcgcagcccc ttttttacag
    16321 atagagggtg ttcaaaagtc agtttctcag tattaagtca attttatgta aaaatgtgag
    16381 aagctatttt tacaaaactt tttttaatac tcataattac ttcttattgc tcctgcggtt
    16441 acttgtcgca atgtttgtga gatattttgt catcgctcaa ggctgaacgt ctctttcaca
    16501 accttttctt tgttacactt cgtttattta aaaagccgtt tttttcgttt catcatgatt
    16561 gcgtcacgct ttactttgaa attacggatg ttatggttaa agacttctga taatacaaga
    16621 cctaaagcga ttgctccagc aatcataatt gcttggaccg cataatgagc cgcttctcga
    16681 taggattcag taacgagatt tcgaaccgct tgataagcta aaccaccagg gactagagga
    16741 accatcccgg gaatattgaa aatcgttacg ggcattttca aacgtttaga gaaaagatcg
    16801 ctgatgaatg ctactcctaa agaaccaagc aatgaaccaa aagcagcaga tccgcctatt
    16861 tgaacacaga tccagtagat catccagcca aaagcaccag aaagaccaca acaaatcaat
    16921 gaacgcctag gtacatttgt aataacggca aatgccgcag tcgctaaaaa actaaaagaa
    16981 aactgaataa atatcgtccc catacttgtg ttcctttcct aataaaaaag ctggaaaata
    17041 aaagcaatcg caaaaccgat catcgtagca gtcatcatcg cttctgttcc gcgagaaact
    17101 cctgagacat aatgtccagc tagcaaatca cggatagcgt tcgtaatttg aactccagga
    17161 actaaaggca tcacacatcc gataatgatt agatcctgat tgcttcctaa gccaaaacgt
    17221 acgctgtaga tagcggctat gccaatcaat aaagaagata aaaattccga taaaaatttg
    17281 attctaaaaa atttcaaact atatagataa gctgcgtatc ccaatcctcc aatgactaaa
    17341 gtcacaggta aatcggtcat ctttccgcca aataacacca taattgttcc actgatcact
    17401 gccgcgctaa cgatttgcaa ccagacagga aagaaagaac ggtctcggtc gattgcttgc
    17461 agttcgcagt aaagttcttc taatgttagc tctgaagcaa catatttacg tgaaagatca
    17521 tttactttta ctactttttc taaattaatc gaacggttgg taatttgttc cattcggatg
    17581 gtcgaggtac gatcaagacc aataaagaga ccggtttgag tgacatagct gaccaaacgg
    17641 aaatttccag aagctaaagc aattcgactc atcgtatctt ctacccgata catctccgca
    17701 ttgctttcca tcatgatttt cccagcgagt aaacaagtgt ccagcaacag atctaattct
    17761 tttcccgtca tagcatcttc tccaataatt gattgattag ttttatttta ctacaaaaca
    17821 taccagaagc gtaaagaata aaaaaacttg aggaaggaat aaaagaggcg tatactgttt
    17881 ttgtattgcg ggtgtagttt agtggtaaaa tcccagcttc ccaagctgat gtcgcgggtt
    17941 cgattcccgt cacccgctta aaataggttg tgaaaaagct gctctgcaac aagtaataag
    18001 aacagccaag caaaaacaac ttcttatgtt tttaacttgg atggacttat taccgcagat
    18061 gcaagctttt gcgcaccgtt taccaagcgg ttgtgaaatc agtgtattgt cttgagtatg
    18121 aagaaaattt ttgaataata ataaatacct tacagataga gtggtgactg attagagacg
    18181 aggaatccgt ctcttttttg tatttttaag ccatcttaaa acaggtttta ttttttgctg
    18241 tttctatttc tttctagtat ttatttatag gggaacatat gttaagattt agggagctgt
    18301 tagtaaagga gtaaagaaat gagcaaaaaa acaaccaagg cgatcgtggg gatcgtcgct
    18361 gctgtgattg caggggcatt cggtgtttcc accacacaaa aagattcaga tatctttcag
    18421 cagattacaa ctatttttga ttccacacca caagcttctc aagtagcgga tgtgccagaa
    18481 tatgatggaa aacatcaaga aatagaaatc aatgggaatc agccggaatt tacaaaagag
    18541 gatcttagcc tttccaaagg aacatgggaa agctattcaa atattgataa attgaacaga
    18601 gtaggacaag ccaatgctat gcttggaaaa gatttgttcc ctactgaaaa gagagagcct
    18661 ttgtatattg acccgacagg ttggaaacaa aagaaattaa gtgacgggca atggttatat
    18721 aatcgcagcc atttaattgg tttccagctg actggtcaaa ataacaacat taaaaacttg
    18781 atgacaggga cacgttcgtt gaatgctcca tacatgcttg ctcacgaaaa tgatattgcg
    18841 gcatatatca aagaaacaaa tcatcatgta cgctaccgtg tcactcctca ttttgagggg
    18901 aatgaactgg tagccagggg agtgcaattg gaagcagaaa gcattgaaga caaaaaaatt
    18961 gaattcaatg tctttatcta caatgttcaa gatggctaca cgatcaatta tgagacagga
    19021 caagcaacaa aaacaaaaaa ttagtagcag ctattcgaat tttttatgaa tattatgaaa
    19081 aaattgtgta aaaacataca ttcaaagaaa tatagcgtat actttatgaa aagagtactt
    19141 ttgataaagc tacagaaaaa aggaaaaaaa catacaaata gtgtttctta atttattcgg
    19201 aagtttggaa tatttgtttg tagttttccc tttcttcgag taaaataagg ttgtagaagg
    19261 taagctggaa ttaccttgcg ggaaagaggt gtagaatcat gggttttaca gatgaaaccg
    19321 tacgttttgg ttttgacgat agtcgcaaaa aagaagtgag cgaaacatta gcgattgttt
    19381 atcgggcttt ggaagaaaaa ggctacaatc caatcaatca gattgtcggc tacttgcttt
    19441 ctggagaccc gtcctacatt cctcgttatc gtgatgctcg aaatttgatt cgccgtcacg
    19501 aacgcgatga gatcatggaa gtaattgtca aggactacct ctcaaatcat ggagtgaatt
    19561 tatgagagta atgggcttgg atgtcggttc taagacagta ggtgttgcta tcagtgaccc
    19621 ctttggctgg acagctcaag gagtagagat cattcggatc aatgaagcag aagaagagtt
    19681 tggctttgat cggttgaagg aattagtagc acaatatgaa gtagaccggt ttgtagttgg
    19741 attacctaaa aatatgaaca attccatcgg accaagggca gaagcttcca tgtcatacgg
    19801 agaaaagatc aaagaactat tctccttgcc agttgattat caagatgaac gattaaccac
    19861 tgttcaggca gaacgtatgc tagtagagca ggcaaatact tcaagagcca aacgaaaaaa
    19921 agtcatcgat aaattagcag ctgtgatgat cttacaaaat tatttagacg gctcaggtaa
    19981 gcaattattt taataataaa agaaaagagg taatcttatg acagaacata accattccca
    20041 cgaccatgaa ggacacgaac acatcacatt ggtggatgac caaggaaatg aaacattata
    20101 tgaaatccta ctaacagttg acggacaaga agaatttgga cgtaactatg ttcttttata
    20161 tcctgctggt gtttcagaag atgaagatgt agaattacaa gcttatgcat acatcgaaaa
    20221 cgaagatgga acagaaggcg agttagaaca aatcgaaaca gacgcagaat gggacatgat
    20281 tgaagaagta ttcaatacat tcatggcgga agaagaagaa tagactataa agctaggaga
    20341 aaccttgata tgatagggtt tctccttttt ttatttttta ctgtatgcca tattgtatgc
    20401 catctagtca atatttaagt gttgtactaa tttttcaaca gtcttttctt tcgtttcttt
    20461 tgccaagtga ccgtaacaat cgatcgtctg actaattttt gtatgccgta atctagtttg
    20521 aacttctacc atagtagctc cagcgtccaa gagcattgaa gcatgagtgt gtcttgctac
    20581 atgcacaccg agaaatggaa ccatagcttt ttcacaaata gtaatcaatc ttgcataaat
    20641 agcgtggtgt gtgattagtt ctttatagat accacaaaaa atcatagtcg gatcagttac
    20701 accaagtgtc agcatatatt tccgctgatt aatctgccat ttttttaata tagaaattgt
    20761 tctttcatct agtggaagaa ccccagcact acaatcagtt ttaggatcac tgattttata
    20821 gccatttttg gattggctta gtgttttatt gatggtgacc gtattttctt gaaaatcaat
    20881 gtctgaccaa ttcaatgcaa gggcttcact gatcctaacc ccgctataaa agagaaagcg
    20941 tagtaacgtt ttatcaaagt cgtttcgata agtttcaggt ttgctgttta ggtaatcaaa
    21001 caaggtgatc agttgttctt tactgtaaac tttgaccttt tctttatgct tagtggtggt
    21061 tcttttaggc attaatacgt tgtctagtgg attagtctca ataatcccaa gattgatagc
    21121 gtagctaaaa atacgcttag aagttgaatg aagtaccttg tattggtcag tagtttcagc
    21181 ccagctattt acaatttgtt gggctttttt taccgtgact tcattcacac gaagatttcc
    21241 atattttgga agaatccact ttctaaactt gatttcagtt ttcatgaagg tggcttctcg
    21301 gacagtggtt ttatatgttt ctagccacaa gtcataaact tctttaaacg tttcgttgtt
    21361 cgctttttta ataccgtttt tatcgtagtc cacttgcaag cgtgacaagg caagctgggc
    21421 ttcttttttt gttttgtaac ctcgtctacg aaccttatca ggtttgccag tcattttgtt
    21481 cattccaaga taggcttcat agagccaaaa tttacctttt ttagtttcat attgcttgaa
    21541 tgttgccata atagttttcc ctccatagtg tagcaagccg tgggggcggt tggaggaggc
    21601 agtttattat tattttgaat agtgtttatt tagctcagta acaagagctg tgaactcttt
    21661 tagaagatca ttttcataaa attcttgata ctcttttttc tcatctgtat ttttttctga
    21721 atcattaatt aatgagtcat atcgtaaaag cgtatttaga agagctgcga gataagcaat
    21781 tggggtactc ccgtcaggaa attcaattcg agatcctgtt ttaagatatt ttattgcgtt
    21841 tgttaaataa atcttctgtg agacagtcag gttatcttct tcgatgttat tgatagcatt
    21901 agaaagatta gaatcaatta tagagttatt tttttcaata gtttttttca attgcttttc
    21961 aagcacattt cgcttaattt cgggcatcat atgcatatct cttaatgtat aagatccgtt
    22021 taatagatag gtagtggata catctaatac ctttgaaagt tgtttaagcc tggtgttatt
    22081 gggaagatta tagccatttt cccaattact aacggcacct ttactggccg gtggggataa
    22141 tttacctcca agttgttcca ttgagagtcc cttttcaatt ctagccagtc taattctttg
    22201 tcctgtctcc actgcttcgg ggtatttttt tctagccaca ttttcaccac cattcatata
    22261 ttttctctac tatatcacga tttaaatatg tgtgaaacat aaaagttcaa aaaagtatgt
    22321 taaaattctt gcaaatgaaa aggtatgatg gtatattgag tttataagag gtatagaaat
    22381 gtattcaaga gcctcttgca tttttttaaa atctttgtat agaaatgtat gctaacgagg
    22441 ggggataaat atggaattaa aaattgacaa actcacgctt gatgatccag cttttaaaat
    22501 tattgacgat cgagttgttc aacaagtaga gcaaactcaa ggaacgttac tttcattatt
    22561 agaaaaaaag taccagtttc caaaatatat gaacaaggca caagctgcta agtatatgaa
    22621 cgtttcatac aatactatga tgcagaaata tgttcctaac ggtttaaagt tgattatagt
    22681 tgatggagtc gtaagaattt cacaagatga atgtgatcgc tttatggaag aataccaaaa
    22741 ataaacgcaa gccgtggggg caaagggatt aataggagga aataataatg gaatcgacac
    22801 aaaataaagc aatcgaaaaa gtattatcaa caattcttac agaagacaca gcggcagaat
    22861 tagcaaactt ggaaggcaaa gcgctagaag aaacgtttga atgtttgtac gaacaaatgg
    22921 actatcaaaa attgctacca caagaaccaa cggtaagcgg agtattgcgt ggcttgaacg
    22981 atttagtaca agcagagttt aaagaacgac tttctattga agagtatcaa gaaattttgt
    23041 atcagcaagt tgagttgtta gcgagcttgc tagggcttga actggaggac gttgaatgaa
    23101 aactgaaatt tggaacggac acattataag atttgtcgat attaatgatg aatggtgggc
    23161 agtggcgaaa gatgttgcgg aagcgttagg tcttaaacag gttactagag ccattcactc
    23221 tttgcctaaa gatggggtta ctactagtaa ggtcatcgat tcattgggca gaacacaaga
    23281 tgtaaacatc atcaacgaaa aaaaatattt accgcatggc attcaaaagc cgtaaaaaag
    23341 aagccgaggc atttcaagac tggattttcg acatcatcaa agaactacgc cagtccacag
    23401 gacttgaagg ctttcaagta ttccgcatgc tagacaaaga acaccaaaaa gaagcaatga
    23461 ctaaattaag ccacgctatt actgaaccaa aaccagtaga ctacattaaa gcgaatgtga
    23521 tagccaataa agctgtatca actatttatg gtcattccaa aatggtaaaa aagaaagata
    23581 tgactcctga aatgttggtt gatcgtgaac ctattttaga tgagacagta gaattaatga
    23641 ctgttaaaga aaaatatggg ttgcagtttt cagtgagtga gaaaatttat aatcgttctg
    23701 ctgaattgca gacaacttag gagcattaac atgatcgaga acaaagaaaa agccttatcc
    23761 ataacagtct tggcggacag gataaaggca acttaattgg gataaaaccc gatattcttt
    23821 gttccgatta taccatatta aaaaatcgga gggaaccatt atgaaacgaa acttaattat
    23881 aggaagcatt ttaatcggcg gaattttcgg cttattacca ttaattgcaa aaatagctat
    23941 ctttgcagga ttagcgttat atctcttcac tgcttatgac gagtacgact atcaattaag
    24001 aactggaggg cataagtaga tgtacaaaac aaaactatta aaccaactcg atagccttga
    24061 attagaggaa attaatcaag ggatcgctga actagaaaat aatatcggga aaacctactt
    24121 tggaaattca ttcaatgaaa aactaacagt tttgtatgta ctcaaaaaac atgcagaaca
    24181 caaaataatt tgtcgagaaa tcaacgagct aaaaaatcag attttaaccg catggttaaa
    24241 cattactgat atgcaagaag caagggtgaa aacatttaat acatgggtaa agtatcagaa
    24301 tcaattaaaa ggtgctgaat ttgttcggga tgggttgaaa tacgaacttg agcagttgaa
    24361 gctcatggag gtgtctgaat gatttatacc agtattttga aaaaggagga gaggtttatt
    24421 ggcaaataat tatcaagcag caacggaatt acaaaagtcg ggatggtcaa tttatccctt
    24481 atctcctgga actaaaattc caataaaagg ctctagtggt tggaatgatg caactaacga
    24541 ttctaatcaa attaatgaat ggtggacgga agatgcaact agaaatattg ggttaatgct
    24601 tgaagatcat caaatggtgg tagttgacct agatcaacat tctgaaacac gaaacggcgt
    24661 tgagaattat aaaaaacttg cttcaatgta tgatccattt ccttctactt atacggaaat
    24721 cacaccaggt aaaggaatcc atttcttctt taaaattcct gatggtgtaa ttatccaaca
    24781 agaaacaggt gcatttgctg atatcttcgg gcgtgatgat aaaggtaaaa gtttaagcgg
    24841 gattgatatt atcactaaag gagttccaat agcgccaact atgattattt caagaagtgt
    24901 tgggagagca tatgaaccta ttgaaaacgt atctctaaat aatattgcac cagctcccga
    24961 ttggctagtg aacctactgc taaaaaaacc gcaagaaata aagactcaat accgacccgt
    25021 agcaaaaaca gggacagcaa aaaaattaga tatgattgtt caaggcgctg gcgaaggtag
    25081 tagaaacgat catttaacta agttatgcgg ttggttacta tggcacggtg tagataatca
    25141 aactttagca gaattgattt atacagcaaa tgcgtacaat gaaccaccgc taaaagataa
    25201 agaagtgaat caaattattc gatcgatgat taaaaaagat ttgaggggga aagctcatgg
    25261 ctcataagca taaattagat agtattttag actttcccga agccagcgag cgtgaagaca
    25321 atatcattga attgaaaacc tggatgtcac gattaagatg caataaagac gatcagatta
    25381 aaagtaacag tgttgtgaat gcagaattga ttttaaccaa tgatagcaat ttagctggaa
    25441 caattgctta taacgaattt agcggataca ttcacctatt aaaagattct ccttggatca
    25501 atcgtaccgc tggagaatgg gaagacagtt ttgaggatgc cttaacggca tatattgaag
    25561 aaaactacaa tgtagttttt gatgacaaca aaatacacaa agcagtagta aatgtggcta
    25621 gaaagaatgt tttcaaccca gtaaaagaac gtatcgaaaa agttaaatgg gatcaacagc
    25681 ctagactgga aacactgttt attgaccttt taggggtaga cgacaacctt tacacacgag
    25741 aagtaacaaa acgttggata gtcggatcag tcgcacgtat ctataaacca ggaataaagt
    25801 ttgagatcgt tccagttttg gatggaccgc aagggattgg taagagtacc gttccagcat
    25861 tactttacac ggatgatttt ttcaccgatt cattagattc gctaggtgaa aagaaagatg
    25921 attatatgca gcttcaaggc aatgtaatta ttgaacttgg agaattatct tcaatgaaca
    25981 aaactaaaat tgaacagata aaaaacttca tcagtgccaa gatcgataaa attagacctc
    26041 cttatggtcg gaatgtcata gcttgggcaa ggcaatgtgt atttattgga acgtcgaatg
    26101 atgggcagta tttgaaagat gatacaggaa accgccgttt ttatcctttg ccttgtaaga
    26161 ataagccaaa gatgaatccg tttaaaacaa aggatgaata ttttcttcaa gtgttagctg
    26221 aagcaaaggt gctttttgat aaaggacaac gaatctattt tagtcccgat gaagataaag
    26281 aagtcttaga aattgcaaaa gactatcaag aggatgccaa gatggagaat ccaattaaag
    26341 aagcaatcac taaatatttg gaaatggaaa tcccgtataa atgggaagaa gctccagcgt
    26401 gggcgagacg ttcttattat cagaactatc ctgacagtaa atgtaatgag aaaaatttac
    26461 agcatttcta taatggagct actatgcaac aagagtttta tttagttgat agcgtactca
    26521 ccgctgatat tttggaagct gtttttgata aacaagcaaa ggatttattg aatggtcgat
    26581 cagatgcaga aactaaaaag attgccttga ttattagcag tattcctggt tgggaacgga
    26641 agcaactgcc aaaaagaaat aaacgacgag gattttacaa taagtcaaat gcctatgaaa
    26701 ataaaaatcg agctggaaag tacaaaaagt aacgggtagt aacgggtcag taacacctag
    26761 cccgttacta gtttaccctt actgccccaa gggatacagc aatttggtaa cggggtaaca
    26821 ccttatttcc ttaaaacttt tgaaatagtt agctaatatg ctggggaata atgttactgg
    26881 attttacccg ttacctgtta ccaaaacgct agaacccttg tccccgttgg gattgagtgg
    26941 taacgggtac ctgttacgta ggtgttacca cgtgttacga atcaaggagg aaagtaaatg
    27001 ctcaatatta tttcaacaaa caaagcaccg aactttcaat atacagatga aatggatcgg
    27061 tttctaatga acacgctggc atttagtgtg ggattggtaa cagaagatta ttccacattt
    27121 gatccagaag tattaaagat aatggaagaa gaacctgatt ggctgcagga gtcagtagcg
    27181 tggtgtcaat cgctagtagt gggatcattg gtagatagtg gcaactatga tgatacaggt
    27241 gagctaatgg atgaatttaa ttgtctgctt aacctatatg atcgagcgag acaacgagag
    27301 cttacatcga atgaggataa tttgttttta aacatccatg ataagttctt ggctttgcta
    27361 ctaacagatg atgaattgat aactaattta ttggaggtag aataattatg catatggaaa
    27421 gtattagata cttcgatggt gagaaacaca ttgagtattc aaacactcaa gaagatgtag
    27481 actttattag ttttgaggaa gataaaatca ctaaagttaa ttttaaagac ggaacgtgct
    27541 tgaagatagt ttcgccttat attgaataca aatcaaaatg ggaacaagat gattctgacg
    27601 aacgagatcg ctttggttgg taatctatgg cagttaaaaa acaatgtaat catgctggat
    27661 gtaaaacatt gattgattat aggcagaagt attgtgggaa gcataaagca aagcaaacgg
    27721 caattaagcg tgaagaaaga aagcaaagcg aaggtaaata ttttcaattc tatcaaagta
    27781 gaacatggcg aaaggcttca tacttgtatc ggttaaatca tccagtatgt gaggattgcc
    27841 tagaagaagg cttgataagg aaagctgatg ttgtagatca caaaattgaa ctaaaagatg
    27901 attggaatag acggttagat gaaactaatt ttcgttcttt atgccatgca caccataatt
    27961 ccaagacagc caatgaaaga caaagacgag aaaagagtac cctttgagtt aagggggcat
    28021 agtgtgaaac ttactgacaa tcgatgccta ctcattttgg tacaaataac cgttgtgaaa
    28081 aggcataagg gtaattacaa ataacgatta cacttgtaat cacaagtgaa aaagtatata
    28141 atgaaagtag gagatttatt gaaaaataca attgttatta ctgataaaac agggaaacag
    28201 cgcaccattg agttacctca ttttggtcaa gtgaccattc aaatgcagaa cggaaaaatc
    28261 atttatatag ataaattaga taaagaaaaa ttctgatcga aaaacgaagg aatgtgagct
    28321 taattgctta cgttcctttt tcttttgtct gaaaggagga caacatggga caccctaaaa
    28381 tattacacga tacaaaaggc aatatatcaa gtgaagaaaa agcaatccgt gtggacgcta
    28441 gagaagaatt gttcaagcag caaccattaa taaatatcac gccccctgac tggatggcag
    28501 cgagcgctag aagtgaatgg aatcgtatcg taccaacatt aaaaaaagat tatccattga
    28561 gtgaagcaga ttatggttca ttggtagcct attgtttagc ctttgctcga atgaaaacag
    28621 ccgaagccga gataagaaaa tcaggtacgt ttatcacatg cgaaaacgga gtaaagaaag
    28681 ccaatccagc ggttcgggtt caatcacaag ctatgagtga tttgaaaaaa caagccacct
    28741 cactaggtat gaccttagaa tcacgatcaa aactagcttt gaacaaggtt aaaaatgatg
    28801 aacccgaaga cccgttcaaa gagttgatga attcatgaat gattacattg agaaagtcct
    28861 atcaggtaag ctgattgcac ccaagaaaat tatccaagcg tgtgagcgtc atataagcga
    28921 tttggagcgt tctaagtcag atagcttccc ttatgtgttc gatgaagaac aagccaccaa
    28981 agcgattaaa ttcattgagt tgctaccatc tacggacggt aaagcaatca agatgttagg
    29041 atttcaaaaa ttcattctag gcagtcttta tggctggcgt actaaagaag ggaattacag
    29101 gcgattcaat cgagcgttta ccagtatgag ccgtaagaat gggaaaacgt atatcgcaag
    29161 tggcatggct gccaatgcgt tgattatgga acaagaacca gcagaagcaa ggcaagtatt
    29221 gtttgtaagt aacgctttga aacaagctaa attgggctat gatatgctgt ctaattcact
    29281 tagaaacgtg gtcaagtcta gtaagttttt aagaccacaa ctgaaaatta tgaactctaa
    29341 gattcagcac ttgccctcta attcgttcgc tatggcactg gctagtgaaa ccagcacgct
    29401 agatgggttt gcaccaacaa ccgcaattct tgacgagtgg cacgaagcaa aaactcgtaa
    29461 aacgtacaac gtcattaagt caggaatgac ccaacaaaag aacggcttat tgtgtgttat
    29521 tagtaccgct gggcttgatt taaacgttcc tatgtacgag gaatacttat tgttagatcg
    29581 tgtgctaaaa ggcgaagaac aagccgacag gtactttata gcgatatggg aattggacga
    29641 tcccgaagaa attcacgatc aagagaaatg gatcaaagcc aatccgattt ttgaaagtga
    29701 agaaatcaaa aaagtaatga ttccaaccat tcaagatgat gtgaaccttg ctttgaaaca
    29761 aaataacctt aattctgtat tggtgaaaaa cttcaattta tggagacaag cgagtgagga
    29821 cagctatatg attgctgaag actggcaggc aaccgaagta gaaccacaag atattacagg
    29881 caagcccgtt tatatcggag tggatttatc taaaacagat gatttaacta gcgtttcatg
    29941 gatcgtaccg ctagataacg gcgaacttta ttgtgattca catagctttg tagccaccaa
    30001 atatgggctt caagacaaag aaaagcgcga cggtttgcct tatcgagaac tagaaaaagc
    30061 tggtgagtgt tccattactc aattagaaag tggaatcgtg gactatgacc aagtatttca
    30121 gtttattcaa gatttgattc aagaaaatga tttggaatgt atggggattt gttatgaccc
    30181 gtataacgct aattcgctta tcagtaaagc tgaaaaagcc aactacccaa tgttagaagt
    30241 aagacaagga acgattactc taaacgttcc gacccgaact tttagagaac aagtttatga
    30301 aggcaacgtt attcacaata aaaatacgat tctcacccat gcagtgaaca acgctatttt
    30361 aaaaacggat aacaacggca ttcagattaa taaatcaaag aacagtaaca aaattgatcc
    30421 aatagctgca ttaatcaatg cctatgtgtt tgcaatggat tacttcacca caacggaagg
    30481 agcgaaagca gacaatgaat tttatacaag tgaagaattt tctttctaat tacattcata
    30541 ccgttctttt acttcttgga ttggtgtgtg tgttggttgc tatcacctta ctaacaaatg
    30601 tctactatgg cttgttagcg ctgggcatag tgcttattgg ggtagcggtc atgctaaata
    30661 cagaacagaa gggaggttaa aagatggcat tttttaaagc gagacaaaat acaacgggag
    30721 atcctttcct acaacatgtg gtatcaatcc aatcggatga ttacaccacc agctttacaa
    30781 gcgttcgtgc attaagaaat agtgatgtgt ttgcagccgt tcgaattatt gctagtgata
    30841 ttgcttcaag tccgattcaa ttggtcaaaa acaatatgcc acaagctgat aatgaactgg
    30901 tgaagttact aaacgagaaa cctaattcag aaatggatgg ttggcattta aagtttgctt
    30961 tggcggtcaa tatgttgcta aacggtaata gctttgcaga gattaaacgc aacggtgaaa
    31021 aggtagaaga aattcactta ttacctaact caagtgtaac ggttactcaa ttagataatg
    31081 gtacgttgtc ttatcagatt ggtgataaaa aaagacgtgt gaagtctagc gatattttgc
    31141 acttcaaata tttcacccaa gatggtttaa caggattacc accactttat gcgttacgtg
    31201 atgaactgaa aattcaacaa gctggcaacc gcacattgca caatttcttt actcgtggtg
    31261 tcagtgggtc aggtattttg aaggttcata agtcagattt agacggatca gcaaagaacg
    31321 caattcgtga aaagtttgaa gaagccaacg gttcaagtag tggagataat gctcttagaa
    31381 cgatcattct tgatgaaaca atggactaca aaacattaga aataaacacc gatgttttga
    31441 agcttatcaa ttccaatgat tggaacacaa aacaaattgc caaggcgttt ggtgtaccga
    31501 ttgagcgttt aggcgttgaa aatgaacatt ctagcaccgt tcaaagtaat ctccagtata
    31561 tccaaagtac gctgattcat tactttaatg tgtttgtgag tgaattagat acgaaacttg
    31621 aaaccaatat ccgctttaat tccgatcagt tactagagac tgatcctgaa acaaaagtaa
    31681 aaaatgtatt ggatcaggtc aaagggtcac ttctcacgat taatgagggg cggtcgaaaa
    31741 tggggctacc ccccatggat ggtggcgatc gtttactagc aagtttgaac tttacgtatt
    31801 tagatacgtt ggagaaatat caattaaaag aacaggaagg agttacacca gttgaataat
    31861 gaagaagaaa aggaaaaacg gctgacagaa gaagctgagc taacagccga ttctcccaaa
    31921 gtagagaaag aaaatgaaaa acaaccaaca gacggcaaaa ctatttcagg ctatgcgttg
    31981 aaattcgggc aaccgtcaaa agatttaggc ggctttgtag aagtgattac acccgaagca
    32041 ttaaaagagg tggatttatc aaatgtgttc ttattatatg gacacgatta ttcaaagcca
    32101 ctagctagtg tcaaagcagg tacgttgaaa ttgaatgtcg atgatacagg attacatttt
    32161 gaagcagagc taaccgacac gacctattca aatgatgtgt atgagaatat ctcaaaaggg
    32221 gttgttgatt ctatgtcctt tgggttcgtg cttggattag attcattcga caaaaaagaa
    32281 gatggcacaa ttgaacgatc aatagataaa atcaaagcac ttaatgaaat tagtgtcgtg
    32341 accgttcccg cttatgattc atcaaatgtc caagtaaata agcgttctta cgaatcgttt
    32401 atgagtaaca accaagcaaa acaaacaaac aatagcttag aatccacttc taaagcacaa
    32461 aaggagagta ataacatgga aaaaacttta atcgataacg aaaaaacaga attgcgtggg
    32521 tatgaagaat atatccgttc acaaggcgaa gtgcgtgatg gagtcactac tgtaaatgca
    32581 gcggcagttg ttcccgaaga agtaatcggt gaagtctttg atttgaaacg ttcaaattat
    32641 aacttagctc aatatgcaac agtaaaaaca gtatcaaatg gacaaggtaa atatccagta
    32701 gcaactaacc aacaagcagt gttagcaaca aaagctgaac ttgctgaaat tggtgatatt
    32761 gacgctgaaa tgtttacttc agttgattat aaagtagaaa ctcgtgctgg taagattgcc
    32821 ttatcaaatg aggttgtgga agattcagca gtgaatattg tacaagaggt caaagatcag
    32881 ttagcgaaat tggtagaaaa cactgacaat aagcatatca tggatttatt aaaaacattc
    32941 actaagaaaa cggctgctac gttggacgat ttgaaacaac tatacaatgt ggcattagac
    33001 ccagcattaa ataaaatggt aattctaaac caaagcggat attaccacct agatacattg
    33061 aaagattcag atggacgtta cattttacaa cccgatgtga cagcacctag tggtaaatca
    33121 ttattcggta tgccagtagt attgattgca gatacattgt ttgccaatcc taaagctgga
    33181 acattcccta tgattatggg ggatattgca caatctatct ttgttgctcg tagaaatcaa
    33241 gtaacgactc aatgggaaaa attcgattac tactcacaag gacttgcagt gatcgttcgc
    33301 aacgattata agaaaattga tcaaaatgct tcagtgtata ttgagtttac gccagttgta
    33361 acaccaaaag tatagaaaaa tattgggcgg cggtttatcc cactgccttt ttttcattag
    33421 gagagataaa atggtaattt tggatagcat aaaaaaaagt atgcggatcg atcacactat
    33481 tgatgatgac tttattcaac aattgattga tacagcaggc gaatatataa aaagtgctat
    33541 tgatagtagc gcaacggata aagatatgga taattatcag caatttgatt tggcggtgtc
    33601 attacttact caacattggt atttgaaccg tcaagaagcc agcagcgaac ggataccagt
    33661 aacggtacaa gcattagtac aacaaatgag aggtgcttat tatgccaatc attaagaatg
    33721 taaatgaatt gactgagaga gtcaagttta aaaagacaaa acgggtaaaa gatgaagatg
    33781 ggcagatggt ggatagtgaa gaaactgtat ttgaatgttg ggctaatgtg cgttcacaaa
    33841 tgctaaaaga cgtgcttgct agtgtaggta ccattcttga aggaacgttg acgtttatta
    33901 ttcgatacga tcaagattat gaactaacaa acgatatgaa agtagcttgg aaaaacaaga
    33961 gttataaaat tatttcaatc aatgaaggaa cggcgtttaa agattataca acgatcatag
    34021 ctaaacagat ttcttagaat gattacactt gtaaacgttg tgggtattta gtataattaa
    34081 ggtagtaaat gaagggttag ctgcctgaat tttgcaagac ttagctagtc gaaatctatt
    34141 gttggactga aaattgtagg tgtggttgca aacatgctgg actaagaaag atgatagatg
    34201 atgaacgttc aattttaata caggcatgct aggactgatt ggatggtttt ggcaagctga
    34261 ttgtgtagaa atcaaagaac acgtctgttg tggacgtgtt ttttttgtta taattcaaaa
    34321 gaggtgattt aatggacaaa gcagagttta caaattttta ttggaagtat tatctacatt
    34381 tagaaaatga gtttattaat accacagatt ttgtgatgct cgatgagaat aatttcaaaa
    34441 cattctctat tgaatatcaa aaactactac tagcgattgg ttcggagtgt gagattattt
    34501 tcaaagaact ttgcggattt gatagcagta gcaataaaag cataactgat tttaaagctg
    34561 ttattaaatc tagcgaatta atgtgtttgg ataatggtgt tagggttatg aattctttaa
    34621 cattgacttc actaaaacct tttggagatg ggtggcctga agatacacca gattggtgga
    34681 aaatatataa cagagtaaaa catggtcgtt cttcaaatta taaggaagca aatttggaaa
    34741 atgtgttgta tgctttagca agtctatatt tattagagga atatttgcat aagaaagtaa
    34801 tactagaagg tgaagtagac tttataagtc cagagtcaaa tctatttacg ttatcttggg
    34861 aaagaaaaca ttcgtcgatg caaaaagtga cgtttgaaaa agtggattca aattatgtag
    34921 ctccactcat tgattttaaa gaacaagaag aaatttaaaa acccccacgg cttattgaag
    34981 tttttgtatg ccatattgta tgccatttgg tttaaatcgc ttgaaaaata gtgatagata
    35041 actctaattc atttagtcat aaacgctgtt ttgataacct ttatagttct ttgatatggg
    35101 tttctcattc atggcggaag aagaagaata gaacaaaaga atgaattaat aagatataaa
    35161 aaaagggatt gtgacaaacg tcttgtcaca atcccttttt ccaaataaac gatgttcaat
    35221 cagctgcccc tcggcattcg ctcgaaaaac ggcgaaatat gaagaactat tttgccattt
    35281 gtttctctaa taatcaggtc aaaacgttga cttcacagtc tcttccttaa acggtgttct
    35341 cctgccaact cctcggtcac aagtcacaat attcaacaaa catgagaagc tgttttttga
    35401 aattgttcct tgtgactcgg agctgaacgg caggctcacg acctctttct taaacggtgt
    35461 tcaaaagctt gcatctgcgg taataagttc aaccaaacga aaattatgag gagctatttt
    35521 tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct tttcgtttag
    35581 cactaaattt ccttaaaaag tagaaaagct ttcgaagcct cgtttgtttc ttttactgta
    35641 taataaaaga aaagagtaac aatcgctaaa agatataaac aagagaaagg aaatacaaga
    35701 tgattggtct gatttatttt gtggtgatcg ttctggcgaa cacagttggc gctatttccg
    35761 ggatgggtgg aggcgtgttg atcaaaccga ttcttgatct tatcggcgcc cattctgttg
    35821 cagggatttc tttttactca acagttgcgg tattcacgat gtccattgtt tcgactgtgc
    35881 gacaagtatc aagcgggaaa tcactgaatt ggcagattgt cggttgggta tctagtggag
    35941 ctgttgttgg aggagtagtc ggcaacattg tattcgaagt ttttttacag ttatttgaaa
    36001 acgagaagca tgtgcagctg atccaaattt ttttgacggt attgaccttg gtttttgcgt
    36061 tcttctacac caagcatcat cagccaaaat ttcatttgac gtcatggact tggtacctta
    36121 tatgtggggg ggttctgggc tttttagcta gttttttagg tattggtggt ggaccagtca
    36181 atgtttcttt gttgatgctg atgtttgcat tgccaataaa agaagcaaca ctatattctc
    36241 tatctacgat tttcttttct caactggcaa aattggtaac gattgcttta acaagtagct
    36301 ttatgcgctt tgatttatct atgttgtttt atgttatccc cgctgctgtt attggaggtt
    36361 tgtggggagc aagatttagc agggttttgt ctccaaaaaa agtgaccttt atttttcaag
    36421 taattgtcct cgtggttctt ttgatcaatc tttacaatgc tttcgtcatc ttacaaacat
    36481 taggagaatc tagactaacg caagtcaaaa tcactgaaac atattgttct aaatgaaaaa
    36541 aggagtatac tgtgataaaa aaattcattt aaaaaaataa aaattggctg gtgatttgga
    36601 tgttgcggga aatgcgttta ggagatgcag aagcactacg agaaatcaat gcggaacaat
    36661 taggatatga tgtaccatta accgttacgg tgagacaaat gaagaaactg ttgaaggagc
    36721 cagaaaaaaa ttttttcttg gtctatgaag atcctacttc taaaaaagca gctggctatg
    36781 tacaagcgga gtcctatgaa tcgattttca gcgatccgat gttcaatatt atggcacttg
    36841 ctgtgtctaa acatgctgaa aaaagaggaa tcggaaaggc cttgatgact ggcgtagaag
    36901 aagcgaaaag acgaggaata tcagcaataa gacttaattc tgcagaatac agagtagaag
    36961 cacaccgatt ttatgaacgc atcggttatc attccgataa aatgcaaaaa agatttttga
    37021 aaatcctgta aatttttatc aaaaaatacc tggtcatcaa gccgatactt gatgatcagg
    37081 tatttttttt gactaagaaa gtaattgcat caagaaacct gagatgatca aaacgatggc
    37141 accaccaagc cgattgccca tttgagcaaa agcaataagt tccatccgat tagctgcaga
    37201 taagacagct acatttcctg taccacccat cgagttgttg cataagccag cagtaatagt
    37261 tgattcgatt ggatataaac caaacaaacg accgacaaat cctgaaacta ctgaaatcgc
    37321 gataacactt gtcaaacata agacaacaaa ttgccatgtc aaagcagaag ccaatacatt
    37381 tagattcaat aacgcaatac cgataccggc aagaacagct gctgtcaagt ttttgacaat
    37441 caagttgttg aacatgatag ctgcatcttc gtaatattct ggtaataggt ttgcgatttt
    37501 acagataaca acgataatga tcatgaatgc gtaagcatgg actttaggaa caaaatagtt
    37561 acagatttgt cctaagatga agaaagtcaa tgataccatc aaaccgacac ctaattgtgg
    37621 aatggaaggt tttacatttc taggttttcc atcgccaagg tcgccttttt ccattaattt
    37681 accattaccg ttgaattttg gcattgattg tcccgcacga gcaactaacg ctgcaccaat
    37741 gatagctagg acatttgtca ttgctgtcgc aggaatcagg cgggaaatga tagaagaagc
    37801 gtccgtacct aaaacatttg cataaatcgt tgataaaggt acagctccgg ctccaacacc
    37861 accagccatt gcgggcaatg agatatataa aacggaattt gcaaaaccat ttccgataag
    37921 catacctacg agtcctacgg caaaaaagga gacgaccatt gaaataagtg caacgggaat
    37981 aaaacgaaca gaagctttca tcaatagatt acggttcata ccaaggatgc taccagtaat
    38041 caaggcagca atataaaagt ctaaaaagcc catattgctg acaaagtttt ctgtggattt
    38101 tactacatac tcaggtaaga tcccaaatgt agcaatcgcg gcagaggcaa agatcgcaaa
    38161 aacggagcca ccacctaaat aacttttgac gatagggatt tttgttccga taaaatgaaa
    38221 taaattaccg aaaatgacca aaacagcgat tgggccaatc atattcgtcg gtaattttcc
    38281 taaagccatt gcaatgatca ggacaaggac catgatcaaa taaaggggca aacttacgcc
    38341 ggtaattttt gttgaccaaa acccttcttt tttcttttcc tcaactgcag ttgcggttgt
    38401 tgttttttgt gccattttta cagatccttt cttattctgt atcgtatgaa aaaagccaaa
    38461 gagaagcggc aaaagagcag tagttggctg gctgctgttt tgccgcagtc gcttttttct
    38521 ttttagacgt catacaaagt ttctgtatgt tcttttacta taacaatctt aatcttctaa
    38581 agatttatat tcaggaaccc atttagcaga ttcaacagct tctttgatat ccgtgatttc
    38641 ttcacgattc aatttttgtg caacaactga ttttgcgaca gtttcagcaa tcgtttgaga
    38701 gaattcagtg atttttgcta ctggaggcaa gatagctgct cctggttttg ttacatcaac
    38761 gattccgcct aatgctcgac tagcttgaga aatgatttca gcatttactc gtgtagctgt
    38821 tgaagcaatc aaaccaagcc ctaaacctgg gtacatcaac gcattatttg cttgaccgat
    38881 ttggtaagtt acaccgttat attccacatc agcagcaggg atacctgttc caactaaagc
    38941 ttttccgtcc gtccattcaa tcaaatcttt tgcttttgct tctgccaatt ttgttggatt
    39001 agacaaaggc atgatgattg gacgtggggt atgagccgcc atttctttca cgatttcttc
    39061 agtgaatgct ccaggttggg tagaagtacc gatcatgatc gttggatgga ttgcttttac
    39121 aactgcttct aagtttgtca attcatcagc attagtgaat tctgagcgtt tacgagcgaa
    39181 tgggatttga ccaggagtca atccttttgt atcttcaaac aataaaccct gtttatctac
    39241 ttgatagaaa tgttggcgtg cttcttcttc aggtacacct tgacggatca tttcatctaa
    39301 aaggatgttt gcgataccta caccagcagt accagcacca aatgtcaaga tcgtttgatc
    39361 tttcaattgc tcacctgata tattcaatcc acctaataca ccagctagta caacgattcc
    39421 tgtgccttgg atatcatcat tgaaagtagt gattttatct tcgtattttt ctaagatcgt
    39481 tgcagcattt cctcgtccaa aatcttccca atgtaataac aattctggga ataattcagt
    39541 agctgattga acgaattgat caatgaattc gtagtaagtt tcgccttcta cacgagcatg
    39601 acgattccct aagtataatg gattattcaa taattcttcg ttattagtac cagcgtcgat
    39661 tgatacaggc aagacttgtg caggattgat accagccgca gcagtgtaga ccatcaattt
    39721 accgatagcg atgtcaacac cgttcacacc ccagtcaccc atacctaaga ttccttctgc
    39781 atctgtcaca acgatcaaac gaatgtcgcg tccatctgct gcgtttttca aacttgcttt
    39841 gatattttct ggttcgtcga ttgaaagaaa tgcagcatct tgtggtttca agaaaatttc
    39901 gttgtattgt tcgattgaat ccgcaacgac aggatcataa acgacaggca tgaattcaac
    39961 taaatgttcg cccatcaatt tataaaacaa tgtccggttc gtattgaata gattcattaa
    40021 gaagatacgt ttttccaaat cggtctgttt gcttaagtat tgaccgtaag cttggacaga
    40081 ttgttgttcc aatgtttgga cagtacttgg aagcatacca gtgattccgt attttgcccg
    40141 ttcttctttt gtaaaagctg ttcctttatt tagaaaagga ttatttaata agtttagccc
    40201 tgtaagcatg aatgattcct cctaagtttt aatacaaacg aagtatagga gtcagatgag
    40261 gatatagtca aaaagagcag gtataataaa ttttatttat atgagtaata gagtcaaaag
    40321 aaatcaaaat agcggtattt gttcttttta tatcaacaat ccttgcttga ttactatgcg
    40381 tatctcttat atgctaaaga aagaaaagta gaagaataaa ggatatgtta gatagataaa
    40441 tagaatctct gaagaataaa tcacgtgatc gtgacgataa aatacactta cgtcaggtga
    40501 taaaaaatac ataagtagaa aactaagagg aggaacagaa aatgaaagaa gttcaattga
    40561 tcagaaaaag cgaactatca gaaggtggtt gcaatgcatg cggcgtagta gaagcaacaa
    40621 gctatacatt aaagcttggt gccaacaaag cgataatctc tgagttgaca gtaggcggtc
    40681 ttgtggacag tctggcgctt gctgaaggtt ttattggaga agatatttat gagatgtttt
    40741 cagaaatccg tcagttaaaa aaaggggaaa actgcataga ggttcatcat gagagcccga
    40801 atgtgagatt caaacgtggt gataatgaga tgatcttcaa taatcatgtg tccgatcaca
    40861 ccgagctata tggaatcgtg aatcaaatac taactgagct ttttggattg ggaccttatg
    40921 cgttcaagga agaaaacggt aatccaaaat taaacgaaga atggcaagaa acgattgaaa
    40981 tacaaagaaa caacccgcac ttatttcaat aggcatccac agtatttcgt aaaagggact
    41041 ttgacacgac ttttgtcaaa gtcccatcgt tttttatcta tttgtgttct aaacatttct
    41101 ttcagagtag taacaactgg aatgactgaa atgtaaacag attatttgcc tgtatcaata
    41161 cggaagagta atataaagtg tgtaaacgct atcatattat tcattcaatt ttttatagag
    41221 ggaaggcatt gaaatggaaa aaacgtatca agcaggtaca aatgaaggaa tagtggattt
    41281 tatcaatatg gaagatttag aaatagccgc ttcacaagtg attccagctg gtggttatgg
    41341 ttacatcagc agtggtgctg gcgacttatt tacttatcaa gaaaatgaac gggcattcaa
    41401 tcatcagctg attattcctc atgtattaaa agatgtagaa ttacccgata caactacaca
    41461 ttttgacaaa gaaacgctga ctgcaccaat catcatggca ccagttgctg ctcatggctt
    41521 agctcatgtg aaggcggaga aagcttctgc aaaaggtgta gcagattttg ggacgatcta
    41581 tacagcaagt tcttacgctt cttgtacatt agaagagata agagaagcag gcggggagaa
    41641 agcaccgcaa tggtttcaat tttatatgag caaagatgat gggatcaatt tggatattct
    41701 tgaagtggcc aagcgtaatg gagcaaaagc aatcgtattg acagcggatg caacagttgg
    41761 cggaaaccgt gaaacagacc gcagaaatgg gtttaccttc ccactgccaa tgccgatcgt
    41821 tcaggcttat caatcaggag taggccaaac gatggatgct gtgtacaaat cttccaaaca
    41881 gaagcttagt ccaaaagatg tagaatttat tgctgctcat tctgatttgc cagtctatgt
    41941 gaaaggtgtc cagtcagaag aagatgtcta tcgttcatta gaatctggtg ctggcggaat
    42001 ctgggtatct aatcatggtg gccgtcaact agatggtggt ccagcagcgt ttgattcgtt
    42061 gcaatatgtg gcagaagcag tagataaacg tgtaccaatc gtgtttgaca gcggtgtacg
    42121 acgcggacag catgttttca aagcaatcgc atcaggtgca gatcttgttg ctattggcag
    42181 acccgttatt tatggattgt ctttaggagg aagtacagga gtccatcaag tgtttgattt
    42241 ctttaaaaca gaattggaaa tggtcatgca attagctgga acacaaacag tagaagatat
    42301 caaaaaaata aaattgcgtg agaatcgttt tatttaagaa acaaatgacg aaaaaaatag
    42361 gagtgcggca gatgatgccg tactcctatt tttatagttc aaggatgtca ctaatagaat
    42421 aatttgaaac gaaaaaataa aattgaaata ttttttcata cttaataaaa aaggaagaat
    42481 attcatgtaa acgattttat tgtttttttc tcttttatac aaaaagggtc ataatttcaa
    42541 gtaagcggat gaattcatga ggattttttg catactgtct ctactatact taggtcacta
    42601 agaaaaagga gtgatttatt atgaaaaaga acatgattgg gacattatta ctttcaacac
    42661 ttcttctagg cggcttggca acaccagctt ttgctgaggg tcaagcgact tcaaaaggag
    42721 atattacctt tactgaacca acaaataccg tggagcctct taaccctact gatccttcaa
    42781 aaccagtaga gccagcagat ccggaaaatc cagcaactgg ccagacaggt cctttaacac
    42841 tggatgtagt tcccgaattg ccatttggta cacacgagat tgaaagcgga acaaaaacgt
    42901 atcaagtaga cgcttcaaaa aacgatacac cttatctcca agtatcagat cgtcgaggtg
    42961 taggtgcaga tggccaagca caagggtgga acgtgacagt ttcggtttca gattttgtaa
    43021 acggttcaca agttttgcaa ggcgctgaat tagattttgg aacatccact gttaaaagta
    43081 cgtcagataa cgaatccact ggaccaacta gtcaaactgt aactgggttg agtaaagcaa
    43141 gtgcagcgac accaatattt acagcagcaa aagatcaagg tctgggaaca tggctttctg
    43201 tttatgatcc agcaaatatc acactgaaag tgccgaaagc agcagctgga acattcacgg
    43261 ctgatttgac ttggaacctc gtggctggcc cagtagcata gagtatgaaa taaattcaac
    43321 aaactgcggt gaaaatacta taggtgaagg attttttacc gcagtttttg ttgaaaggat
    43381 gtggtggaca atgaatcaaa gtaaacgact gtttgtttcg tttttttcta ttttaagtct
    43441 atttttcatt tttccgtcaa tcagccaagc aaaggattca gcaggagact ttggaatcaa
    43501 accggtattt ccagagaacc aaatagataa agcaatcggt tattttgatt tattagtggc
    43561 accggaacaa aatcagacac tagaagtaat tatcagcaat tcttcagatg aagaacgaac
    43621 atttgaggtc tctgtcaatc cggcggtaac gagtgatggt ggaacgatcg attatagtca
    43681 aaaaaaccca acgttagatg agacattgcc gtttgatgtc cgtgacgttt tgctcattgc
    43741 gaaaaaggaa atcaatgtat cagcacatgc agaaacaact gtacctatag aagtgaaaat
    43801 cccagcaaaa agctttaagg gacgtgtatt agcgggtatt catgtttcac ctaaagaaga
    43861 agctgaaaca gaaaatgcta cagaaggagc acaaatcaaa aatcgtattg cttataatct
    43921 cgcagtcgtt ttacaagaaa gtcaagagac gatagaaccg gatctgaaac ttttatcagg
    43981 agatttggac gaggtcaacg caaagccaac tgttcagctt cgtttccaaa atcctcagcc
    44041 taggattatc agcaatttga tatttacgag caagatcttt tatgaaaatc agctttatat
    44101 tgaaaatacg tctaatgcat ttttagttgc accaaattcg aattttcact tgaatcttga
    44161 tttagctggt gataaagcaa aagccggcga ttaccgcgca gaaatcatag caaaatcagg
    44221 cgacagtaat gaatggcgat ttacacaaaa ctttacgatc aaaaaagaaa aagcacaaaa
    44281 agtaaatgaa aattccgttt ttgcagtaca agaacaatct ttcccatggc tttatgcagg
    44341 attggttgct gcagttctag tgttatggtt gattttgctg tttttgtggg tccacaagaa
    44401 aaagaaaaaa ggagaaacaa catgatgagg tgatttcgtt gaaaacatcg atcttattgg
    44461 gagggattat tgcaagtttg ctgttcttca gctggcaaga gccagtccaa gcagatacca
    44521 aaagttcagg tacgattaca ttttatgatc taagtccaat tccgcatcca agtggttcag
    44581 tcaatggcgc atcaaaacag cagacacagc taccgattta taaagaatct aatcaacatg
    44641 gcgtattccc ggagacgaat gaacaaaaga tccgttttct ttatttgatc attggtatag
    44701 aattatggct tcttgcgtgg ttgttgttat ggagaagaaa ggaaaaggag gatgaacatg
    44761 ttgctacaaa ataaattttc attttttcgc tccttctttt ttacttcgct ttttgtttta
    44821 agtatattta tcttttcacc ttcggcagaa gctgttggag caacgcctcc tgccatttct
    44881 tatgatccat acacgtatga aaatatcgta cctccaaatg gtggacgtag tgcagtcaat
    44941 ggcgggaagc ttgtccaact aactggggct aaccaattgc ctaaattgac tgctacttat
    45001 ttgaacgatg gttcaaatga tccttggaaa ggtggcacgg tccgttttca ttgggaaagc
    45061 catgtgaaac taacaaatgt acttgatttg gtgaatatca ctgcacaagg atttgcattt
    45121 gtggcgatca tcaatttgcc ggaacatgta tcaagcagtg atgtattaaa agcaattgac
    45181 tggaacaacg cctacttgta tattgccggt gcccccatca aggttactag cggaagttta
    45241 ttatcagcag gaagccatac cttgcgtttt gggatggggt cgtgggatac aaatactcta
    45301 ttgacagata ttattgctat tattacgcga ggcgaattca acgtggacga tatcccgctt
    45361 caatttgatg ttacagctaa tgtcgcgaag atgacagaaa acggagataa atatgatacg
    45421 agtccaaaca aaattttgac caagggtaaa ttacaacctt ctatgtctaa aaaggccgtt
    45481 ttttctgttg atttttatga ttcgaataat attatccaag atcgtatgtt caattcgatt
    45541 ttagctccag ctgcaggtag attttatcct aaattaactg gcggaaactt gaatccagga
    45601 gcatatgcat tttctgcaag tgcagagata aatacgtgga atagttacat ctcaccaagt
    45661 gattcaacag gaaaatataa tacatttgct gataccacag aatacgtgga tggaaataac
    45721 cagaaccttc caggctctac caatagtcgg acattgacga tggggctgac tgaaggacgt
    45781 tttgatcagt tgccatttag tcgctttgat cgcgtagtca actattttac aggaaaaaac
    45841 gttacacaag gagcaatact gactcatact ccagcaagca caagtggatt gaatcagaca
    45901 gccaatatcg tgtacagtgg gaaagatgcg caaggcggat tgctttctcc tgttgcttta
    45961 aaggtattgg agcagtacaa gctagacgga acggttttac caacaaactt aacagccgat
    46021 agtcagtggg gaaagctcct ttcttctgca tcgtaccaag tcacggccaa ttggtcagca
    46081 actgaactaa aaaagggttc gatccattac aggctttatt cgaaaggaac ccaaaaatta
    46141 gcgacaggat ggacagatca acttttccaa acgatccaat caaataacgg gggtgtaaat
    46201 acagctactt ctacactacc tgcattggct tcagggcaat attattttga ttatcgcttg
    46261 gtggacgatg tacttactaa catgtatccg tcttttgcgt acaaatggca gtctgaacaa
    46321 gctggaatca ccactcttcc tcaaataaca gtggctaatt ttccatctgt gagtgcagat
    46381 agtcagctaa aaaaccttag cagacaacct gagacaggag atcccctgtc tgctctatca
    46441 ggagatacga ttcaagaaaa tgtgacattc acgttaacaa aatctgggga tgcgataacc
    46501 gacaaaaaaa tcacgatctc acttcctgaa aatactactt atatcaatgg ttccttaaaa
    46561 ttaaatggta caactatcgc agataccggc attcaacaag gagtttctgt cccagcagat
    46621 ctattgagca aaataggaga taccattcat cttacttaca actatcaatt aaatactgta
    46681 gatacttctt tacaatccgt cagcatactg acaaaggcag ctgtactttc cagcaatatt
    46741 acattagcag atggtgctaa gcttcctaac ccagttgtcc aaacatctgc taaaacaatt
    46801 cttgtcccca aacaagaatt aacattagtt aatgtaccag atgattttac atttggtaac
    46861 gatctcccca aaccgttgaa gacaagttat tatgaatcaa aaggcgattt ttcttttgat
    46921 gtgcgggata ctcggcttcc aagcacgtct ccttggcaac tgacaggtac attgacttct
    46981 ttatttaaga atgatcaagg tcaagaatta agcggaacaa aattatactt caatcattct
    47041 ggatcaaagc aattgattca gcaaggtcaa aacacgttga tttatgagag tgatggaaca
    47101 gctaaaggag aggttctcgt tgactttccc gataccgatg gtttactctt agaggtaaat
    47161 agcagtacga atgctcaacc tggcgcaacg tatcaaggca tggtcacatg gaaactgaca
    47221 gctgggccaa ccagctaagt gattagaatt tgtatggatc tgtgataact gtcacagatc
    47281 ctctttttca aggatgagaa ggaaacttct gctgttaaaa tcagaaatgc ttgaaggagt
    47341 ggacttggaa cttttcagtt tgcttgaaaa aaatgaacaa cggcaaatca aacttttcca
    47401 acttttatta gaggaaaaag gagaggtttc cgttaataac gtacttaccc gcttatcagt
    47461 tgatcgggct accttgaaag aagatctgtt ttatttacaa gctaacttgg aaaatatcaa
    47521 acaattggaa attgttatcc aagaagggaa tattttatta atcagacatg gaaatatagc
    47581 agcagtcgat gtttattatc attgttactt gcgctattct acaaaatatc agatacttct
    47641 ttatctgttg gaaaatggct catttgatcg gcagaaactt gtcatggaac ttaatatcag
    47701 ttcggctact ttgtctcgca gagtgaagga attaaatgat tctttaaatg agtttcatct
    47761 gaaaataaaa agcgggcggc tgaccggtcc agaaagtcaa attcgttatt tttatttcca
    47821 attattttgg tttggacgtc cctatcttga aaacaaaaaa gaatacagtg atttatcagg
    47881 aaacactttt ttagatctgc tgcaaaaaga gtttagtttt gctattacag aagaaggacg
    47941 attgaaattt gaaatatggc tttccattat gaagaagcga atgcgctgta cgaaaaaatc
    48001 caaaccagat tatagcaatc ttcctgttgg attgtttcaa acgacacaat ttttattgga
    48061 cctccataca tttttgaccc gttacttctt tcaatatgcc tttccttgga atcaaaatga
    48121 aacgttggtt ttttatcttt tcatgatcag taactttaca ttagatacac ataactcgca
    48181 tgtccaggag tttttgataa gcgaaaaata caaagacgac gtagtagctc aattgaatcg
    48241 aacgtttaaa caatcgatag aagaatattt ctctttttat gtttttccag aagagatttc
    48301 gcaaaagatt gcgttgacag tgatgcaaaa tcacgctcat tttgcctatt ttagaggatg
    48361 gatgaatatt tttggccaag aaggattaaa acagcggtta actgaagtag aagataaaca
    48421 attcctggtt ttatgtgaaa gattggtcag acaaacattt gctattgttg attttactga
    48481 agtagacgag gaaaatgccc gctttgaatt atttgctcgc tatgcatcta ttttacggac
    48541 gctgatcaag cagttagaat tacgtctgca aattgcttat gatcttcctt atgaaaggct
    48601 aatggcggat atcgtgaaag aaatcatcca ggaacaattg ctgaatacga tcaaatatga
    48661 tttagtcgaa tacgagaaag aaaagcagta tgatatcatt ttgactagcc aattgaaaga
    48721 gtacccgtca cagaagtccg ctaaagtttt tgtattcact agcaacgaat ataattatga
    48781 tttcccctat ttgaaccaat ttttaaaaga atgttattta gaaaaattga atttaaggat
    48841 gaataaaaca tgaaaatcgt gatcattggt gcttcccatg caggcatcac agctgcccta
    48901 aatctaagaa aacttcaacc gaaagcagaa gttttactga tcgatgaaga tcataaagat
    48961 ggactaggct atgtttcaaa tggaatcaac ctttatttaa aaggaaagat acgtagttta
    49021 gctgaagttg cccataacat gcggactctt caagaaagtg gggcaaaact gatcaccgaa
    49081 tggagagtaa ctgaacttga tccagacaaa catcagctca tcctcgcatc caaagaagga
    49141 aaaaacgaga ccataaccta tgataaatta atcgtagcga caggttcctc tcctgtcacc
    49201 ttgtataaac aaattgaagc tgaaaatgtc tacacctata aaaatctagt gcaatctaag
    49261 caagtacttg ccgctttaaa agaagcaaaa gaagtagtga tcttcggtgc tggttacatt
    49321 ggattggaat tagcagatgc tttgagaaat aaaggataca ttattcatct agttgattat
    49381 atgccgaatg ttttatcaag atatttcgat aaggatatga tcaacagttt tcaaaatcag
    49441 ctgcaaacta agcaaataaa tttttatcca aatgaattct tgatcgattg gaaaaaatca
    49501 gaagagaaag tagtatccgt acaacttctg tctcaaacaa taaaggcaga tatggtcatt
    49561 ttttctgccc aaactcgtcc taatacgaca ttgttaaaag aaaaagtggc tttgtatgag
    49621 gatgagactg tgatagtcaa tgaatatctg cagacaagtg atccggacat ctatgcgatt
    49681 ggagatatcg tcccagtcag ttttgacaaa aataaacggc atctcttttt acctttagtt
    49741 actcgagctg tacatatggc aagagcagta gcgctaactt tgagtggtca gccaaccgct
    49801 tacgacctca gacaaaagat aacagcagca gtcattatag actacttttt aggaactgta
    49861 gggctgacag aagatgaagc gccattcttg gaacaaaata ccggttcgtg ttcaggagaa
    49921 tttgatctat ttccacaata cgacgaagaa aacaaaacag taaatgcaaa gctgatctac
    49981 catccggata cattagaaat aattggcgga cagctgataa gccaagaatt cttattatca
    50041 gatttgaacc tgcttgcgga tatcgtgaaa cacaaaacta cgattccaca gctagcagtt
    50101 gaggattttg gatttctgtc tgaatacacc tctcgttttc actacctcaa tgagttagct
    50161 tttaaagtac tagctaagag agcaaatagc aatagagtag ataaaagact gtgagaaata
    50221 tcacggtctt ttattgtgtg gggatataat aaatattaat caatcgagaa taaaaaattc
    50281 atataatgaa atagcggaag aattttttga gcataatatt cgccaaaaat ttatcaagtg
    50341 ataaaattgt tgtataaaat gattatttca ggaggaggag ttaaatgttt ttagcattaa
    50401 atgaaattat gcattcaaag ttacgttatg cgttagttgc aggggtgatg tttttgatcg
    50461 cctacctggt attttttttg actgggttag cttatggctt agctcaagat aatcgaacag
    50521 cagtcgacaa gtgggaggca gattcgattg tgctttcgaa agatgcaaat tcaaatctag
    50581 ggatgtccat gattactaag aagatagcag aagaagtcga aggtgggaaa gtggcgtatc
    50641 ttgcccaaac acctggagtc gtgactagta aagacagtac agaagaagga aaaatcaatg
    50701 ttagcttctt cggtatcgat aaaaatcaat tcatcatgcc caatcttgtt gaaggaaaag
    50761 cttttgataa cgatgatgag gcagtaggcg atattagttt gaaagaagaa tatggtctag
    50821 ccataggaga tacagttaag ttatctggta gtgacaagac gtttaaacta actggcttta
    50881 cggatcatgc caaattcaat gtctcaccag ttctctatac aaccatcaat gcttaccaag
    50941 aaatccgctt cgaaaaagaa gatacaagtg aaaatgcacg gattaacgca atagttgtca
    51001 gaggtaaaat cagtaattta cctgaagatt tagaacagat caaaatttct aaattcatca
    51061 atgaattacc tggatataat gcgcaagtat tgacttttgg atttatgatc ggatttttga
    51121 tcgttattgc ggctattgtg atcgggattt tcatttatgt actgacgatg caaaagatta
    51181 atatctttgg tgtaatgaaa gcacaaggga tcacaggagg atttattgcg cgttctgtag
    51241 tggcacaaac attcatttta tcatttgttg gtattcttct tggtctatta ggaacagtgg
    51301 gaacatccct tgttctacct gatgcggttc cattccaaag caattggctg ttttttggcg
    51361 tcattagctt gttgatgtta gtagtagctg tgttaggcgc actattttct gttcggacaa
    51421 tcgtaaaaat cgatccgttg aaggcaattg gataagaagg aggaagaaca tgaaagcaat
    51481 agaatttaaa gaagtagaaa aaagtttcca agatggcgac caagtagtta aagcattgaa
    51541 agaaacaacc atgagtatcg ataaagggga atttgttgca atcatcggtc cttctggttc
    51601 aggtaaaagt acttttttga ctttggcagg cggattgcag acgcctagca gtggctctgt
    51661 atttatcaat gatcaagaat tcagtaatca aaaagaaagc gaacgcgtta aactacgttt
    51721 taaagaaatt ggctttattt tgcaagcttc caatctggtt ccttttctga cagtaaaaaa
    51781 gcagttatta ttagtagata agattaaaca tgaacatcgt caaaaagaag caaacgaatt
    51841 atttgagcag cttggcgtgg ataagttgat caacaagtat ccagaagaac tatctggtgg
    51901 agaacggcaa agggtcgcaa tcgctcgtgc attgtacaat gatccgtcca ttattctagc
    51961 agatgaacca actgctagtt tggattcaga aaaggcacga gaagtagtcg atatcttggc
    52021 aaaagaatca aaagacaaaa ataaagcaac gatcatggtt actcacgata cacggctgat
    52081 tgacaaatgc gatagaatat ttatgatgga agatggtgta ttgaaagaaa aagaataacc
    52141 aaaaagcagg tggaaaaatg gtccatcgat acaacaaaga tacacagcaa aaaattttga
    52201 aagaagcgac tgacttgttt atgtccaagg gatatctcgg cacttcaaca agagaaatcg
    52261 cacaaaaagt tgggatcacc cagcccaatc tctatcatta tttcggtgat aaagaaaaac
    52321 tatatacggc agttttagaa aaccacttaa aagatgttgg aaaagctttg agagaaatcg
    52381 ttcaaacaag cgaaacggga tttcaagtaa ccttgacaaa aatggcgcag tttttgattg
    52441 agacacatct ggtcgatttg tttctgatgc ttcacgatct tgaaagcaat ctttcaaagg
    52501 aaacaagaga tcatcttttc tttctatgga agaaaaatta tcgtgaacct tttgaagaaa
    52561 tcttttcagc aaaccaatct gtgctaagaa atgggatttc aaaagaaatc gcagcaaggc
    52621 attttttctt agtgttagca ccttacatca ctcggtcgaa aagacctgtg gaagaaccgc
    52681 taaatgtggc gcaattgatc gatttatatt tgaatggtgt attaggagaa gcgtaaagct
    52741 gttatatagg gagaaaatag ttaggtgaag aagcaagata tgacgaagat cgttatatct
    52801 tgcttcttta tataggtagt ttttcataaa gacaaatttg ttattctctc atgattatca
    52861 gggtatattt ttatttatta tgtcggtgtt ccaggaagtg ttttaattta ataacgaaga
    52921 aattaattgt ttgtagaatg aaggaaacta tttattgggt agatgaatca ccacgaatag
    52981 tcaaaaggag atttcaggat atgccaaaaa tgaaaaaaat cattttagca gtaatgttat
    53041 tttctacggt tatatctttt acagcccctt ttttgcttac ttaagctgat tttaagtttt
    53101 ggcccttagt ctggatctac gaggtgagag tcaagaatga aaaaaataat tggagctttt
    53161 gtatttgcaa tcattatcat tattatctgt tttcaaatag atgtttttgg tcaaaaaaag
    53221 atagttggac aaacggtcag cagtacgaac agtacggtta caaagacaaa ggaatcattt
    53281 gatgatacag aacaagagac attaatcaaa atcggaaaaa atgaccgtac actatataca
    53341 gatgactcgc taactacccc acttgcaact ataaacggcg gagagctggc ggagtttctt
    53401 tctgaaacaa aaaatgctta tcagatcaag acaaatgatg gctatactgg atatttagcc
    53461 ctcgaagatg gaaccaaagt cacaaagaat atacaaacaa aaccggaaga gctatctgat
    53521 gcagtgattg tattagatcc tgggcatggc ggaaatgata ctggggcatt aagcaatgat
    53581 gaacaaacag aagaaaaaga tataacatta agtacagcca taaaagtaaa aaaggcgcta
    53641 gaggatgctg gagcaacggt ttatttgacc catactacag atgaattagt acagcttgga
    53701 gatatatgcg actacagtga agaaaaaaag gcagatgtct ttatcagttt acacgcagac
    53761 tctacggaat atgcgaatga agcaactgga atcacgacat attattacta tggacaagag
    53821 gaaacattag cacagacaat tgctgactcc ttcactgatc tgcctctgga ttcaagagga
    53881 atctccactg ggaactatca agttcttcga gaaaatcttc aaccttctat tttaatcgag
    53941 atgggttata tgaataatga tagtgattta aaggaattag taacagacag ttatcagcag
    54001 cagattgctg caagtttgac acaagcattg accacttatt ttcagtaata aataagccca
    54061 gccaaacaaa aatagctcct catatttttc gtttggccgg gcttattatc gcagatgcaa
    54121 gcttttgaac accgtttatt tttttagtag cttcaaagct ttttctgtat ttgcaaagtg
    54181 aagtttggca tatttttcaa gcataggcat gccgcctttc tccaatagtt ttgccgctac
    54241 ttggtcagat ttcgttccag ctcctgatgg aagggtgatt ccagcttcag ctgatgcttt
    54301 gtgtaactct tccaaaaagc tggcacgact gatgatagaa gcagcagcaa cagctaaatg
    54361 atattgttct cctttagtaa cgaagtacag tttttcttgt aattgatttt tttctaaacg
    54421 cgcatatttt ttaaaatttg cttccggcgt aaactgatcg atcaaaatcg cttctggttt
    54481 ttctggctcg atttttttta gcagcaaatg gatcgcttga ttgtgcaaag cgactttcat
    54541 ccgaacggca ttgtattttg gttggatctc attgtatttt tctggagata agacaagcag
    54601 tttatagggg atggtttttt ttaagatgtc agcaagctgg atgatttggc tatcttttaa
    54661 ctcttttgaa tctctaacac caagtttacg taattctgca agctgatcac gtttcacata
    54721 agcagcacat actgttagcg gaccgaaata gctgccattt ccgacctcat cactacctaa
    54781 aacggataat tgactgatat tttttggcaa agaagaggct gtttttgctg gcttggcttg
    54841 tttatcctgt gcctcccccc atttatcagc ttctattgct gcattcgtac cttgaaacat
    54901 cacttttccg gatgtataag cggtaatggt cgtcccgtct ttttttgcag caaagctagt
    54961 ataaggaatc tgtttattta acaaataaga gcgatagtat gctttcattt gactaagttg
    55021 gtcgtttgtt gctttgataa tgacgttgct cataaaattc tcctcgtttt tatacataaa
    55081 actataccgc aactcacgac ttttcgtttt ctaagagatt gcgagacata gcattttttt
    55141 aaagtttatc atataatagt taagtatgtg aaaaatattt gtggagaacg gtgaaagaac
    55201 caacttcatg gtacactaaa taaaactttc atcaaatagg aggaaatgat tcgtatggcg
    55261 cacgaaaaaa cacgctacaa agcggtgatt gccaaccaaa catatactat tatcggacgg
    55321 gaaaccaagc atcatatgga tatcgtaacg aagctgatca atgaacagtt agcagaattg
    55381 aaacaattat caccacaaat ggataatgaa caagcagcaa tcttgatggc tgtcaatgcg
    55441 ctttcggatc aattgaagaa acaagaaaga atcttggagc tggaagaaga aacagcagaa
    55501 ttaaagaaaa aaatgatcaa atttacagag cttgaaaatc gtgtgaaacg cattgaagca
    55561 atcgagaacg aagctcggga agtattgaaa gaaaatggtc aagcagatca taccattaaa
    55621 aatcatgtgg aagcacaaca gattttaaac gagaaacgaa aaggacaaat taaacaaaaa
    55681 tcttctaatt aagatccttt tatcaaaata agaaaaattt aaaaaaagtt agaagagaaa
    55741 ggaacgtagc atgctgagtt tgctgatttt atttttattg ctaattgcgt ttttttctgg
    55801 agcacgtcgc gggtttgctt tgcaaatcat attcgcgatt ggatatgtat tgtcatttat
    55861 tgctgcccag catttttaca aaccattagc aagtcatttg gaattataca ttccataccc
    55921 agctgtcacg ccaacatcaa agttagcatt ttttgatcag gtatttgcct ttcacctaga
    55981 tgaagctttt tatgcaggaa ctgcttttct gattattttg ctaattggct ggctgcttac
    56041 ccgatttgtg ggggtttttg tccatggatt gacgtatgtg ccgatcttga gacaggtaga
    56101 ctggattgca ggaggcatcc tgtcactaat catggcttac gttactatat ttttgatttt
    56161 gcagttactt gcctttgttc cattagatgt ggtccaaaat caattcggcg agcatagttt
    56221 cgctcgcttt atcgttgaga gaacgccatt tcttaccaac aagatgtatg agctttgggt
    56281 aacgaatatt ttgaattaag gaaaatagtg ctggaaaata tttcgttttt tgtacagagt
    56341 agattattta agaaggctgc gtagcgtatg tccggcacag ctcttttttc atagtgaaag
    56401 ataaggtgat aaaatgaata accgaatcct tgaaacattg gaatttgaaa aagtcaaaca
    56461 gatggtcaga caatttgtag tgactgcaca aggaaaagaa gaactggcag aattggtacc
    56521 agtgagcgag gaacaaacga tcacaaactg gcttcaagaa actgaggatg gattgaaagt
    56581 gcaacgtctg cgaggcggga tccctatacc taaacttgaa aatatccgtc cccatatgaa
    56641 acggattgag atcggagcag acttgaatgg agtggagctt gcacaagttt ccagagtatt
    56701 gtctacgaca agcgaattga atcgtttcat tgatgatctt tatgacagtg aaatcgaatt
    56761 tgcacgtttg tatatgtggg cagatcagtt agtcacgatc cctgttttga gccgccgttt
    56821 aaaggaagca atcgatgaag acggacgcgt gactgatgac gcttctcctg agttaaagag
    56881 cataagacag aacattcggc gaagtgaaca agctgttcgt gaacagttag atgggatcgt
    56941 ccgtgggaaa aatgcaaagt atttaagtga tgcgatcatc accatgcgaa atgaccgcta
    57001 cgttatccca gtcaaacaag aataccgcgg tgtatttggc ggtgtagtcc acgatcaaag
    57061 tgcttcagga cagactttat ttattgaacc aaaacaagtg gtggatttga ataatcgttt
    57121 gcgtcaatac caaatcgctg aacgaaatga gattcaacgt attttaagtg aactttctgc
    57181 tgaacttgtt ccccatcgtc aagaaatcat ccacaatgct tatgtgattg gtaaaatgga
    57241 tctgatgaat gcaaaagcac gatttggtaa agaagtaaaa gctatcgtgc cgggaatcag
    57301 tgaagacaat catgtcgtct tgaaacaagc aagacatcca ctgatcgatc aggaaaaagt
    57361 agtttctaat gacatcacaa tcggaaaaga ctatcaagcc atcgtcatta caggacctaa
    57421 cacaggtggg aaaacgatca cgttgaagac tttaggtctg ttacaactga tggggcaagc
    57481 aggattaccg attcctgcag gtgaagaaag tcaaatcggt atttttgagg aagtatttgc
    57541 ggatatagga gacgaacagt cgattgagca aagtctatcg accttttctt ctcatatgac
    57601 gaacactgta gatattttat caaaagtcaa tgaaaaaagt ctggtattat ttgacgagct
    57661 cggtgcagga acagatccgc aagaaggtgc tgctctagca atcgcaatct tagatgatct
    57721 tggtaaaaag tctgcttatg tgatggcaac aacgcattat cctgaattga aagtttatgg
    57781 atataatcgg gcaaatacga ttaatgccag catggagttt gatgtggata cattaagtcc
    57841 aacgtatcgt ttgctgattg gcgttcctgg acgaagcaat gcgtttgaaa tctctagccg
    57901 attaggtctt gatacagaag ttattgatga agcgaagcag ttgatgaatg atgagagcca
    57961 agatttaaac gaaatgatca cagatttaga gaatcgccgg aaaatggcag agaccgaata
    58021 tctggaaatg cgtcattttg tttctgaggc acaagaactt cacgatgatt tgaaagaagc
    58081 ttacagctat ttctttgaag aacgtgaaaa agaaatggaa aaagcaaaga aaaaagcaaa
    58141 tgaagtcgtg tcagaggcgg aagaaaaagc agaaaaaatc attgctgata ttcgtaaaat
    58201 gcaacagcag attgggcaag gaaatgtgaa agagcatcag ttgatcgatg caaagaccca
    58261 attagcaaat ctacatcaag aagaaacttt gaagaaaaat aaagtattga agaaggcgaa
    58321 agaacaaaaa acgttgaaac cgggagacga agtgttggtt acgacttacg gccaaagagg
    58381 gacgctttta cgtaaaaacg ggaatcagtg gcaagtagaa atcggtatat taaaaatgaa
    58441 tgtgtccgaa gacgagctga cgcctgttgc tcctcaaaaa gagccgacac aacgagttat
    58501 ccatgctgta cgatctgaat ctagtagtca cgtgccgaat caattggacc ttcgaggaaa
    58561 acgatacgaa gaagcgctaa gtgaggtaga tcaatatttg gattctgcca ttctagctgg
    58621 ttatcctcaa gtgactattg tccacggaaa aggaacaggc gcacttcgca agggaattac
    58681 tgattatctt aaaaaccatc ggagcgtcaa aagctttgag tttgcaccgg caaaccaagg
    58741 cggaaatggt gcgacaattg ttaaatttaa gtaaagctta ctaaaggtaa gcagatggtt
    58801 cgctatccaa gtatagaaat gctatactag tcatagattt taaaaatgga ggtctttgat
    58861 atgtcacaag taattacaga taagacattt aatgaagaaa cagataaagg acttgtattg
    58921 attgattttt gggcaacttg gtgtggtcca tgtcgtatgc aagcaccgat tttggatcag
    58981 ttggaacaag aatatgatga agaagaattc agaattgcta aaatggatgt ggatgaaaat
    59041 ccagaaactc ctcaacaatt cggtatcatg agcattccaa cattaatgtt gaaaaaagat
    59101 ggtcaagtag tagaaaaagc tgttggtgtt cattcaaaag aacaactacg tcaaatgatc
    59161 gatcaatatt tataaaaact tacagcaaaa ataagctgag ggtgggactg aatccagttc
    59221 cgtcctcggt ttttttgcgg ttgagttaag gttattcaaa ttaatatttt ttgagtataa
    59281 ttacgttgtc aggctggatt gtttttttga cagacatgct ataataactt taattgaata
    59341 tgaaggggag taccagatga acgaacgaat caaaaacaaa ttagctttac ttcctgatca
    59401 gcccggctgt tacttgatga aagataaaaa tggaacgatc atttatgtcg gcaaagccaa
    59461 aatattaaaa aatcgtgtcc gctcatattt tactggtagc cataatacga aaacggaacg
    59521 gcttgttagt gaaatcgaag actttgaata catcgttaca gaatcgaata tcgaagcatt
    59581 gctcttagag atcaatctga taaagaaaaa tgatcctaaa tacaacatta tgttaaagga
    59641 tgataaaacc tatcctttcc ttaagataac gaatgaaaaa tatccccgtt tggtgattac
    59701 tcgtaaggta ctaaaagaca aagcactgta ttttggacca tatcccgatg tcggtgcggc
    59761 gaatgagaca aagaagatcc tcgatcgatt atttcctctg agaaaatgca aacctagtca
    59821 gacgaaggag ccttgtcttt actatcattt gggacaatgt ctgtgtcctt attatttcga
    59881 cgtagatccg aaagtctata cgaaaatcgt tgatgaagtg aaaaactttt taaacggagg
    59941 acacgaaaaa atcgagtcag agatccatca gaaaatggaa aaagctgctg aaaacatgga
    60001 gtttgaaaaa gctgcagaat accgagacca gatccgtgcc attgagacaa tcatgactcg
    60061 ccaaaaaatg acaaatactg atttactgga tcgagatgta tttggttatg cgattgataa
    60121 aggatggatg tgtgtccaag tgtttttcgt aagacaagga aagctaattg aacgagatgt
    60181 ttcaatgttt cctttctata acgaagcaga agaagatttc ttgacttacc tcggtcagtt
    60241 ttatcaggaa aatgagcatt tcattcctaa agaagtcttg attcctgata cgatcgacaa
    60301 gcccagtgta gaagctttgt tagctacgaa agtgctgcaa ccaaaacgag gagaaaagaa
    60361 aaaattagtt gaattggcga gtaagaatgc ctcagttgct ttgaatgaac ggtttgatct
    60421 gattgccaga aaacaggaac ggacgatcgg agcagttgaa cgtttaggaa acgcgatgaa
    60481 tatcccgacc ccaatacgta tcgagtcttt tgataactct aatatcatgg ggacgaatcc
    60541 tgtggctgcg atggtcgtat tcattgatgg aaaaccggca agaaaagaat atcggaaata
    60601 taaaataaaa acagtcaacg gaccggatga ttatgcatca atgagagaag tcatctatcg
    60661 cagatattcg cgagtgattc gcgaagggtt gcctttacct gatttgatct tgatcgatgg
    60721 aggaaaagga caagtagatg tggcaaaaga tgtcttagaa aatcaattag gaatcgatat
    60781 tcctattgct ggcatggcaa aaaacgataa acataaaaca aatgagttgc tattcggtac
    60841 agatttggct gtagtaccgc ttgagcgaaa ttcaccagag tttttcttac tccagcgaat
    60901 ccaagatgaa gtccatcgat tcgcaatcac tttccatcgg cagctacgca gtaaaaacag
    60961 ttttgcttcc cgattagatg aaattgaagg gttaggacca aaacgaaaaa aaatgctgct
    61021 taaagagttc aaatcgttga aaaatatcac agcagccacg acagaagaat tacaagaaat
    61081 cggactgccg aaaaatgtcg cacaaaacgt atttgataaa ttacatcagg aatgaggaaa
    61141 gggcacttta caaagaaagt aaagtgtcct atcattttat gtacaacaaa aagagcgttt
    61201 acgttttgtt ggtaaataat aaatcgctta cgtctggtgt ctaaggatat atgtgatttc
    61261 ttgaagaagg agtgaagaaa tgttagaagt caaggatctt gttaaaactt ttgggaacta
    61321 cacagctgtc gatcatgtct ctttccaaat ccccgatgga aaaatcatgg ggctaattgg
    61381 ccaaaacggg gctgggaaga caacgacttt tcgtttgatc ttggattttt tgacacaaga
    61441 ccaaggagaa gtgttatgga atggccatca tcttggggag aaagattatg atgtcatcgg
    61501 ttatcttccg gaggaacggg gactttatcc gaaagtaacg attcaagacc aactgcttta
    61561 ttttgcagaa cttagaggga aatcaagaaa agagattgaa ccaaaaatcg acttttggat
    61621 ggaaaaattt caggtaaaag ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa
    61681 tcagcaaaaa gtccagctga tcgccacgtt aatccatgaa cctaaattga tcattttgga
    61741 tgagccattc agcgggttag atccggtaaa tgctgaattg ctaaaagatg gaatattgga
    61801 attgaaaaaa catggttcat gtgtcatttt ttctagccac aatatggata atgtagaaaa
    61861 aatctgcgat catttgatca tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca
    61921 tgagattcgt gaatcatttg gccgtacgaa gttattcttg gaatctggtt taagccaaca
    61981 ggaagtagaa gaaatcgaag gcgtgaaaaa agtgatcctt catgaagaca atacgttaga
    62041 gattacctta gaagatcctg aagctgggaa agaaatcttt actcgtgcga ctcagttcgg
    62101 ctacattcct atgtttaacc agcaaccgcc aactttggaa gagattttca aattgaaagc
    62161 aggtgaaatc gatgcgtaag ttttggatta ttaccaaaga tgtctattta aaaaatgtta
    62221 agtcgatttc tttcttgatc atgatattag tcccttttat catgctgggt atcatttatg
    62281 tagcaggaaa ctttgctcaa caaaatagtg atgtcaataa aatcggcgta ttggctgata
    62341 atgagcaaat cagtcagcaa atgagccaag tcaaaacaga tgattttgag ttcaaagcag
    62401 ttgattctga agaaaaagca caaaaagagc tttcggaaga aaaaatcgat gcgtatttag
    62461 tagtctcaac tgagaatgat aagataaatg ggatgcttta tagcgaaaat tcattaggac
    62521 aaagtacaca actactgata caacaacaac tgactggctt gcaatcgatg cttcgagcga
    62581 gtcaattagg catttcacca gaagaagtag ctagcttgag ccaacaagca agtttgactc
    62641 gacaaaaagt caattttgat tcaaaaggaa aaatgacagt cggagaagat aactcgacag
    62701 tccaatacgt cgtaagttat gtagcaacga ttgtcttgtt cattattatt ttgacgtatg
    62761 cgcagatcat tgcacaagag atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc
    62821 tgtccagtac gactgcacaa aagcattttt acggaaaatt aacaggtgtt ttacttgttg
    62881 cattaacgca aatggcatta tacggtatta tttttggtat aggatacagt caattcaaag
    62941 atatggaaat ggtcaaaaat atattagacg gtatctcatt ggataacttg attggaccat
    63001 tcttgtggta ttctcttcta ttcatgatct ttggcatttt gattttttct gttttagcag
    63061 ctttatgtgg ctctttggtc aacaaagcag aagatacagc aaaagcaatt ttgccagtga
    63121 cttatctatc tctaggcgga tacatgcttg gattgatact aggagcttca gatccaaaca
    63181 atatcgttat tcggatcact tcgtatattc cattcttatc ttcatatatt atgccggttc
    63241 gcttagcaaa tgagacagtc ggtatgggtg gagcattgat ttccttgttg gtacttgtag
    63301 ccgtaacatt cttattgatg atcttgtctg caaacatgta caaatcgaat gtactcgttt
    63361 atagcgaagg cggattatgg agttcattga aacaatcgat ttcaattatg aggaatgaac
    63421 gaaaaaaagc ataaaacaat cctaaaatac agaaggaagc tggacatcta ttgttcccag
    63481 cttctttttg tatagaccta ttttatttat tttactatat tggatatata ttcattgaaa
    63541 atagtgtata acaactttat aatattgagt ataccaattt ttggaggcgt tttaatggac
    63601 cgttatttag atttactttc agaaaaattc ccctcaacgg aggatgtcat cacggaaatc
    63661 atcaatctcg aagcaatttt gcagcttcca aaaggaacag agttattttt gagtgatata
    63721 catggcgaat ttcctgcttt tgatcatatt ctgcgtatcg gttcaggaaa tcttaaagaa
    63781 aagatcaaag accttttttc tgaacaaatg acggaaacgg atatcagcca attcactatt
    63841 tttacggctt atccagaata tgcattaacg actgattggt acaaagaaca agataaatcg
    63901 cagctgatcc atcatttgat cgatctttta cggtttacga cagtcaaata tacccggtca
    63961 aaagttcgaa aaggattgcc gaaagaatat agctatatca ttgaggaact cttgtatatc
    64021 gatgaccgta tcaatggaaa aaaagactat gtaaaaaaaa tcattgaaca acttgttttg
    64081 atgaaggaag aagaaaaatt tttaacgaaa cttgcacaga cgatccaaaa atctgtcatc
    64141 gatcatttgc atatcgttgg agatattttt gaccgaggaa ctcaagcagc caaagtgatg
    64201 gatcgaatca tggatttttc ttctgtagat atccaatggg gaaatcatga tattttgtgg
    64261 attggtgcgt attgcggctc tgaggcatgt ttactgacac ttttacggat tgcagcacgc
    64321 tataattatt tatttgaatt agagaaagaa tatgggttga atttacgtcc attgttttct
    64381 tttgctcatc aaacttatca gaagaatcca gtatttgcgc ctaaaaacag taaaaatcta
    64441 tccgaaagag agcaagaaga attagaaaaa atccatcagg cactttctat ccttcaattc
    64501 aaatcagaac atcagttatt ggatcgtcga cctgaattta aaatggacga tcgtaaattg
    64561 ctggaaaaaa tcgactatga agcatcaacg attgatttag aaggtcagct ctatgagttg
    64621 aaaggaactt gttttcaaac gatccagcca gatgatccaa aaaaattctt ggaagaggaa
    64681 caaaaagtga ttgatagttt gatgtattca ttccagcact ctttgagaat gcaaaaacat
    64741 atgacgtttt tgatcgaaaa agggggaatg tatctcacga acaatcagca tgtgctgttt
    64801 catggctgta tacctgtaga cgagaaggga cagctcttag catttgaatt agaccaatct
    64861 tatcgcggaa aagaactgct gggctttttt gaaaaacaga taactgaaag cgcaaaagat
    64921 ctgactgcaa aagaagattt agcaaccgat ttgatttggt atgcgtggag tgggccattt
    64981 tcgcctttat tcggcaagag taaaatggcg acttttgaac gttattttct cacagagcct
    65041 catacgcacg tcgagaaaag caatccttat tatcacttgc gagatgaaga gtggttcagt
    65101 gaaaaaattt tagcagaatt cgacacaaaa gaagaagggt cagcaatcat taatgggcac
    65161 acgccagtaa aagtaaaaaa aggggagtca ccgatcaaag caaatggaaa agtatttgtc
    65221 attgacggag gtttatccaa agcttatcaa aaaacgacag gaattgccgg ttattcacta
    65281 ttatgcaatt cttatggttt ccaaatcgtg acacattatc cgtttttgcc tattgaacaa
    65341 caatttgcaa aaaaatccga ccaaacaaat gtgaaaaaag taatcgaaca gcaactacca
    65401 cgcaaactca atcgtgatac aacaaaaggt atggaactgc agcagcagat tacccagctc
    65461 aaaaggctgt tggactatcg aaaggacgat tgagaagaat tccagtgaac attgttccat
    65521 agactggaga ctgagacaaa agtcgtgtcg cagtctcttt ttccggataa acggtgttct
    65581 tctgccaact cctcggtcac aagtcacact attcaacaaa catgaaaagc tgttttttga
    65641 aattgctcct tgtgactcag agttgaacgg caggctcacg acctcttggt ataaacggtg
    65701 ttcaaaagcc agtttctcgg tattaagcca aatttatgca aaaatgtgaa aagccatttt
    65761 cacaaaattt ttcttaatac tcgaaactaa acagcttttt cacaaccccc tcagaaagtc
    65821 tattaaaatt cattcacaaa gaaatcgaat aagcgctgtt cagatggatg tacacggtgg
    65881 gtaagttccg gatgccattg aacaccgagg attttatgca tatcatcttt gctttgaacc
    65941 gcttcaatga gtccatcgtt agaaaaagcg atggctttta ataaaggtga aagatctttg
    66001 actgcctgat gatggtaaga attcacaaaa tatggatcgg ggagaaggtt gcttaacaaa
    66061 ctgtctgaaa caatcttgac ttcgtgagtc gtaaattgcg gggcagtggg ctgttgttca
    66121 tgttttactg accactttgg atataatgaa agatcttgat aaagtgtacc ttccaaaacg
    66181 acattcaata gttggagtcc ccggcagact gcaaaaattg gttttctttg tttcaatgct
    66241 tccaagatca gtgcctgttc aaattggtct cgttgaatat ttgtttccgt tagctttgga
    66301 tgaggatctt ccatgtaaag ttgtggactg acatcttgac cacctgcaag aataagtttg
    66361 tcgatttgtc caatcagttg aggagctgaa tctggagaca tgactggcag aataagaggc
    66421 aatccttgag catctaaaac tgcatccacg aatccttgcg gtgtatagct cacttgattt
    66481 ccttggaaag tatctgttgc tcgaatcagt tgatttccgg caatgccgat gattggtttc
    66541 atttgtattc cccctaaagt agacttattg taacaaggat ttaaaaaaaa ttaaactatg
    66601 taagacttgc ccctatactt atctgttctt gctgtgttac tatctgtaaa gagaaatttc
    66661 gtgtgaaatt catgacgata gttgaaaata ttgcttaatt tgttataata aaaagtaagc
    66721 agaaataaaa aggttgggcg taagcttcaa ggatctagtt cttcaagggg tgagaaggac
    66781 attttattga aggggcctgc ctatactaag ttatctttag aggtacatac tttcaatgaa
    66841 aaaagaaagc atgtacctct tttttaaatc gaaaggaagt gaagcaagtg ttagaagctt
    66901 tggaacaaat ccgaaaagca gaagaagaaa atgaaaagcg tgctcaaaca ctgcggcagc
    66961 agctgaagat ctatgcaaca gaaaaagagc aggaattgga aacgatccaa acaaactatc
    67021 gacaacaact aaaacagttg gtggaagaaa aagaacaatt tgaaatacaa gaattagaaa
    67081 aagaaaaaat gaaattgaaa gcagaagcag acaaggtgca agcaactttg aaagatcaat
    67141 atcaaaagca tcagagtcaa gcgatcggtg cgatcattga aagggtgaaa gaaacttatg
    67201 gccgtcacta agatggaaaa agtgaccctc atttcagata aaagaaatca ggagaggatt
    67261 ttacaagcag tacaaggaat ccaaaacgtt gaaatccggg atctgtatca aaatagaaca
    67321 aacaaccagt gggtggagaa gtattttcca gataccacga ttattgataa agaagcaaaa
    67381 ttaagcgctt taggtaatcg gttgaaagac atccaagaag ctatccaatt catacaacac
    67441 cacggcgata gccgtcaaaa gaaactccat ttgaaacgtc aagaactttc cttacaagat
    67501 ttggaagcca attattccga agaaaatttc ataaataaat tgaaagaagt ccttgattta
    67561 aaagaaaagt gggaacaact aactgaagaa cgtgatcgtt tagaagaaga ggaagaatgg
    67621 cttcttcatt ggcaacagct ggatattgct ccaagtatgt atgcaagtaa gacgaccatt
    67681 tttgagatgg ggactgtgag tgcagcaaat tttgaaagtt tcaaggaaga actgagtaag
    67741 cttgatgacg tttatatgga agaaatagat tatacgccaa aacaagttta tctttcgtat
    67801 gttgctttaa aaaaatcagt tgctgttata gaagaaattg ctgggaaata cgggttcaat
    67861 aaagaaacgt atccttatga acaaaatcct aaagaaaaac tgcaagagac caagcagcaa
    67921 ttatccattg ttcacgagca gcaaaagaag ataacgacag cgttaggtca gtgcagtggc
    67981 tatatccaag aatttgaatg ggtagaagaa gtcacacttg ccgttgcaga acgagaaaaa
    68041 ataaaagaac ggtttatcca tgcgacttat ctgatcgttt tgcaaggttg ggtagatgca
    68101 gaagaaaaac agaatttgct gcatgtgtta aacgaaaccg tatcagaaga agatatatac
    68161 gtcagtttcg aaacaccaaa ctcagaagag attcagcagg aagtccctac taaattgaaa
    68221 aaccatccgc ttgtcgaacc ttttgaattg ctgactgaaa tgtacagtct gccaaaatat
    68281 gaagaagtag atccaacacc ttggatgaca ccattttatc ttgtcttctt cgggatgatg
    68341 gtcgcagatg ttggttatgg tttgctgatg ctcattggga caatactagc tcaaaaacta
    68401 cttgttctac cacgcgggat gaaacgtttc gtaaaattct ttgagattct ctcgatacca
    68461 tcgatcatct ggggattgat ctacagttca tttttcggac agtcattacc aaaagaactg
    68521 tttggcatcc gcttgccttt cccaatccta tctacgacgg atgacgtcaa tacgattttg
    68581 attttatccg tgattttcgg tctgatacag attttggttg gattatttgt ggcagcaaag
    68641 gaaaatatca ggagaaaaga ttacttgagt gctgtcagtg atggatttgc ctggcaaggg
    68701 atcctaattg ggatcgttat tgcgttggtt ggtgccatgt tgataaaaaa tacagcattt
    68761 gtttaccttg gcgctgggct atcgatcatt gctgccttat gtatcttgat cgttccgatt
    68821 atccaaacgc cgtctaaagt caaaggtgct gccaaaggtg cgtataatct ttacggactg
    68881 accggctata tcggtgattt agtcagttat acacgtttga tggcattggg tatttcaggc
    68941 ggaagtattg gagcggcatt caatatgcta gttgctttca tgccgccagc tgctcgattc
    69001 agtgtaggga tccttttgat catcgcttta cacgcactga atatgttttt gacactgcta
    69061 agtgcctatg tccatggcgc acgattgcag tatgtcgaat tttttgggaa gttttataca
    69121 ggaggcggac gtgcctttga tccgctgaaa acggcggaaa aatacgtcaa catcaatcac
    69181 aagaaaaaaa acaataaata attggaggat ttttatataa tgatggatta cttaattagt
    69241 caaaatggtg gaatggtatt tgcggtatta gcgatggcaa cagcgacgat tttttcaggg
    69301 atcggttcag ctaaaggtgt tggaatgaca ggtgaggcag cagcagcatt gacaacaagt
    69361 caacccgaaa aattcgggca ggctctgatt ctgcaattgc ttccaggtac gcaaggtttg
    69421 tatggattcg ttattgcctt tttgattttt atcaacttag gaaatgacat gtcagttgta
    69481 caaggactga actttctagg tgcttctctg ccgattgctt ttacaggctt gttttcaggt
    69541 attgcccaag gaaaagtcgc agcggcaggt attcaaattt tagcgaaaaa acctgaacat
    69601 gctacaaaag gaatcatttt tgctgcgatg gttgaaacat acgcgatttt aggtttcgtt
    69661 atttccttcc tattagtgtt gaatgcctaa gcataaagga ggaaaagcag atgaacgcca
    69721 ttgaaaaaat catctctcag atgaacgaag cagcagagca ggaaagagcg gcgttagaac
    69781 aagaagagcg aatgaagatc gatcaaaact ttgaacaaaa acgtacgcaa gttgaaacag
    69841 aacatcaaaa acaaaaagaa aaacaaatcg aattactcga aaaaaaatac cgtcagctaa
    69901 ggaatcgcca gcaagtagaa gtacgacaag aaaatttgaa tgcgaagcag gaatttttaa
    69961 gacgattgtt tgcagatgcg gtaactgaaa tggaaaattg ggatgaatct gaacaaatcc
    70021 agtttatcaa aaatgcattg tattcattac ctttgacagg aaaagtagca ttcattgctg
    70081 gagaaaaatc agcagcctat ctttctcaga cgttgttgga tgaatggaac aatgaacttc
    70141 cctttatgat ggttttaagt gatgaaactg ttgctgatca agcgggtttt ctgataaacg
    70201 atcaaggagt tcagtataat tttcttttca gcagccttgt acaagatatc caaggaacga
    70261 tgagttttga gattgccaat caattattcg aataaggagg gatcagtgta tggaatacca
    70321 cgaactaaat cccttgattc gcggaagaga gcttgaactt ttgtccaatg agacatttga
    70381 acggatgatt caaacaaatt ctgtcgaagc acttggtgaa atattgaaat ccacgattta
    70441 cagtccatat atttatgacg gatatgaata tgacttcgaa cagaatcttt taaaggagca
    70501 gagccgtcta tttcgctggt taaaggaatc agcaccggag cctgaaatcg tttggatcta
    70561 tacgatgcgt tatactttcc ataatctgaa ggttttgaca aaagctgaga tgacaaatca
    70621 aaatctggac catttgtata tcgacgatgg attttattca ttagaaacct tgaaggatgc
    70681 cattcatacg caagtttcaa atgaacttcc tgaaagcatt atggacagta tacgagaagt
    70741 acgtgattat tttgaagagt ctaccattct tcagggaatt gacgtgattt atgatcgaca
    70801 gtttttgaca gagcagcgac ggcttgccga taagctagga tatcaagaat tgctgacaga
    70861 agtcattgct tttattgact tgaccaatat cacaacgatg gctcgaggaa tattgcagaa
    70921 aagaacatat gggttcatga cgacggtact ttccagctcg ggaagtatcg aaaaagaagt
    70981 atttttgaac tttgtagata aagatatgga agattacacg aattttctat tagagacaga
    71041 ttatgctgat tttctgcgcc ctgtcatccg tgagggaaat attgatctcg taaagcttga
    71101 acagttgaaa gatgattatc taagttcatt gtatcaagaa gcacaaaccc aggctttcgg
    71161 accactgcca ctactagcct ttttgaacgc aaaagaggta gaaagcaaaa accttcgttt
    71221 actggttatc ggcaaaagaa gccatttcga atcagaaaca atcagaaagc gggtgagaca
    71281 agtctatgac gcataagatc ggtgtagttg gcgacaaaga ttctgttttg ccattcaaat
    71341 tgtttggctt tgatgttcgt tatggtacaa ccaagcaaac cgttcgtcag gcaattgaag
    71401 aaatggcaaa gaatgagtat ggcgtgattt atgtcacaga gcaatgtgca gcattgagcc
    71461 cagaaacgat cgaacgttac aaggaacaaa tgatacctgc tatcgtattg attcccaatc
    71521 atcaaggatc attagggata gggctggaag aaattcaaaa aaacgtagaa aaagcagtag
    71581 gtcaaaatat cttatagtat gaaaaggaga tagaaatttt gcaaattgga aaaatcataa
    71641 aagtctccgg acctcttgta atggctgaga acatgtctga tgccagtatc caagacatgt
    71701 gtctagtggg agatctagga gttatcggag aaattatcga gatgcgtggc gatgtggcgt
    71761 ctattcaagt atatgaagag acttctggaa ttggtccagg cgaaccggtt cgctctactg
    71821 gtgaagcttt atctgttgaa ttaggaccag ggatcatttc acaaatgttt gacggaatcc
    71881 aacggccatt agataccttt atggaaatca cacaaagtaa tttcttaggg cgcggagttc
    71941 aattgcccgc attggaccat gagaaaaaat ggtggttcga accaacagta gaagccggag
    72001 aaacggtgag tgctggagat gttatcggga tcgtagaaga aacaaaagtt ataaaacata
    72061 aaatcatggt gccaaatggg ataaaaggaa cgatcaaaac aatcgaaaaa ggttcattca
    72121 ctattgatga aacagtatgt gtcattgaaa ccgaaaatgg tgacaaaaat ttgacgatgc
    72181 ttcaaaaatg gccagtaaga cgtagtcggc caatcaaaga aaaattaaac ccggatgcac
    72241 ccatgatcac tggacagcga gtgattgata cattcttccc agtgacaaaa ggaggagcag
    72301 cagctgtacc tggtcctttt ggtgcaggga aaacagtcgt tcagcatcaa attgcaaaat
    72361 gggccgatgt ggacatggtt gtctatgtgg gatgtggcga gcgtggaaat gagatgacgg
    72421 atgttttaaa tgaattccct gaattgattg accctaatac aggagaatcg ttgatggaac
    72481 gtacggtatt gattgctaat acatcaaaca tgccagtagc agctcgagaa gcttctatct
    72541 atacgggaat cacaattgcg gaatatttcc gtgacatggg ttatgacgtt gctatcatgg
    72601 cagactccac ttcacgatgg gcagaagcac ttcgtgagat gagcggacgt ttggaagaaa
    72661 tgcctggtga tgaaggttat ccagcttatc ttggttcacg gcttgcggaa tactatgaac
    72721 gatctggaag agtcattgca ttaggatcag aaggtcgcga aggaagtata accgcaatca
    72781 gtgctgtatc cccgtctgga ggggatattt cggaaccagt cacacaaaat acattgcggg
    72841 tcgtaaaagt attctggggt cttgattcca gtttagccca aaaaagacat tttccttcga
    72901 tcgattggat acaaagctat tctctttatt caacagaagt agggaagtat atggatcata
    72961 tccttcaagc tgactgggca tccatggtca ccgagggcat gcgtattttg caggaagaac
    73021 agcagctgaa tgaaatcgtg cgtttggtag ggattgattc cctttcagat aatgaccgtc
    73081 tgacattaga agtggcaaaa tccattcgtg aagattattt gcagcaaaat gcttttgatg
    73141 atgtcgatac attcacttca agagagaaac aattcaaaat gttgaagatg atcttgacct
    73201 ttggtgaaga aggacgccgt gcgttgtcgt taggtgctta tttaagtgag atcatggacg
    73261 gtaccgtatc gattcgtgaa aggatcggac gaagcaaata tatcccggaa acagaattag
    73321 aaaaactaga tcaaattatt ggtgaaatca agcaaacgat gcaaacgatc gtttcagaag
    73381 gaggcatgag caatgattaa agaatatcgt acgatcggtg aagtcgtcgg tccattgatg
    73441 gcggttgaaa aagttgctgg tgtcaaatat gaagaattaa tcgaagtccg tatgcaaaat
    73501 ggcgagattc gtcgtggaca agtattggaa gtccaagaag ataaagcaat ggtccaaata
    73561 ttcgaaggaa caagtggtat caatttacgt gactcttctg tacgattttt aggccatcct
    73621 ttagaactag gtgtatcgga agacatgatc ggtcgagtat tcgatggttt gggacgaccg
    73681 aaagataacg gaccagagat cctgcctgaa aagcatttgg atattaacgg agaagtaatc
    73741 aatccagtag ctcgggatta tccagatgag tttatccaaa caggtatctc tgcaatcgat
    73801 catttgaata cattagttcg tgggcaaaaa ttaccagtat tttctggctc tggtcttcct
    73861 cataaagaat tagctgctca gatcgcgcga caagcaacgg tactcgattc atcagatgat
    73921 ttcgccgtag tctttgctgc tattggaatc acttttgaag aagctgaatt tttcatggaa
    73981 gattttcgtc aaacgggcgc aatcgaccgt tctgtcatgt ttatgaattt agcaaacgac
    74041 cctgcaatcg aacgtatcgc tactcctcgt atggctttga ctgctgcaga atatcttgct
    74101 tatgaaaagg gaatgcatgt tttggttatc atgacagaca tgaccaacta tgcagaggca
    74161 ttgcgagaga tttctgcagc acggcgagaa gttccaggaa gaagaggata tcctgggtat
    74221 ctttacacga acttagctac tttattcgaa cgagcaggaa gaatccgcgg actaaaagga
    74281 tcggttactc aaattccgat tctaacaatg ccagaagacg ataaaactca tccaatccct
    74341 gacttgactg gttatattac agaaggacag atcatcttga ctagagagct ttacaagagt
    74401 gggattcagc caccaattga tgtactcccg tctctttcgc ggttaaaaga taagggaact
    74461 ggacccggaa agacaagaga agaccatgca gctacgatga atcagctttt tgcagcctat
    74521 gcacaaggaa aacaggcaaa agaattagcc gtagttttag gtgaatctgc tttatctgat
    74581 gtagacaaga tctatgcgaa gtttgctgag cggtttgaaa aagaatatgt caatcaagga
    74641 ttctacacga accgttcgat tactgaaaca cttgatctag ggtgggaact gctatcgatg
    74701 ttgccaagaa ccgaattaaa acgaatcaaa gacgacatgc tggacaaata tctgccagaa
    74761 gggaagtgag ttctgatggc acgattgaat gtgaatccga cccgcatgga attgactcga
    74821 ttgaaaaaac agttgacaac tgccacaaga gggcataaat tattaaaaga taagcaagat
    74881 gaactgatgc gtcaattcat cctgttgatt cgaaagaaca accagctgcg tcaagaaatg
    74941 gaagagtcta tgacagaagc aatgtctgat tttgtattgg caaatgcttc gatcacggaa
    75001 cctttcatcg aagaattatt tgttttgccg gcggaaaacg ttgatttgtc tatcgtagac
    75061 aaaaatatca tgagtgtaaa agtacctgtg atgaattttg aatatgatga acagctgaca
    75121 gacacacctt tggaatacgg gtatttgaat tccagtgccg aactggatcg gtcaatcgat
    75181 cggtttacta ccctgcttcc aaaacttttg gaactgacag aaatcgaaaa aacttgtcaa
    75241 ctgatggcga gtgaaatcga aaagacacgt cggcgagtca atgcattaga atatatgacg
    75301 atccctcaat tagaagaaac gatctattat attcgtatga agctggaaga aaacgagcgc
    75361 gcagaagtaa caaggttgat caaagtaaaa aatatgggta ccactgacta agtggtatct
    75421 ttttttaaaa gaggaaaacg atgattaaac aaagcaaaca aataaagaaa cgtttgccgg
    75481 ctgttcagct tctcgcatta ggattttttc tcctgatttt agttggcggc ggcctactta
    75541 ccctaccatt ttttagtaat agtgggcatg ggacaaattt tatcgatgcg cttttcactg
    75601 caacttctgc tgtctgtgta acgggattga caacattgaa tacagcagag cattggaaca
    75661 gtgctggtca atttttgatc atgcttttga ttgagatcgg cggtcttggt tttatgatgg
    75721 ttccgattct atgctttgca ttgataaaga agaaagtcag tctcagcaca cgtattatat
    75781 taaaagaagc gctgaatcta gaagaagtat caggtgtgat gaagctcatg ctttacatcc
    75841 taaaattggc ctttgtgatc caattgattg gtacggttgc tttatctttt gtatttgtgc
    75901 ctgaatttgg ctggttgaaa ggtatctggt acagtttgtt ccatgcaatc tctagttttt
    75961 gtaatgcagg gtttgatttg ttaggagaca gtttagccaa tcaccagcaa aatgtttatt
    76021 tgatcatggt ggtatctgct ttgatcattt ctggtgggtt aggcttcatc gtatggcgtg
    76081 atttactgga atatcatcag aaaaagaaga tgacgattca ttcaaaaatc gcattaaccg
    76141 ttacaggtac ccttttatta ggcggattcg ttgtgttctt tttcacagag cgcaatgggg
    76201 caacgctagt ggaagggaat atgtttcaac gattggcaaa cacctttttt atgagtgtga
    76261 cacctagaac ggctggatat tattcagttg attacctcca tatgagccat gcaggtctga
    76321 ttttaacgat gtttttgatg tacatcggcg gaacatctgg gtcgacggcc ggcggattga
    76381 aaacaactac gttaggtgtg ttgctgatcc agatgcgttc gatgttgaaa ggacgtacga
    76441 gagcggaagc atttggccgt accatccgac aaggcgcagt gttgcgggca cttactttat
    76501 tttttgttac gttgacgttg tgtgtagtcg ccatcatgat tttatcggtg actgaaacga
    76561 tacctaaaac ttctggcatc gaatatattg cttttgaggt cttctctgcg tttggtacag
    76621 taggtcttac gatgggattg acgccagact tgactgcaat agggaaattg atcattatag
    76681 cgcttatgta cattggacga gttggtgtat tgactgtggt cttctctctg atgacaaaag
    76741 cacaaagaac acaatcaaaa tacaaatatc cagaagaaag tgtcatgatt ggataatttc
    76801 atcttct
//
LOCUS       DADVXK010000003        74826 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.003, whole genome shotgun sequence.
ACCESSION   DADVXK010000003 DADVXK010000000
VERSION     DADVXK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 74826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.003"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            53..1342
                     /locus_tag="KB909_000152"
     CDS             53..1342
                     /locus_tag="KB909_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBB6836217.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(1381..1986)
                     /locus_tag="KB909_000153"
     CDS             complement(1381..1986)
                     /locus_tag="KB909_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBB6836218.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(2191..2655)
                     /locus_tag="KB909_000154"
     CDS             complement(2191..2655)
                     /locus_tag="KB909_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6836219.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(2677..2997)
                     /locus_tag="KB909_000155"
     CDS             complement(2677..2997)
                     /locus_tag="KB909_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6836220.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(3141..4220)
                     /gene="pepA"
                     /locus_tag="KB909_000156"
     CDS             complement(3141..4220)
                     /gene="pepA"
                     /locus_tag="KB909_000156"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBB6836221.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            4420..4770
                     /locus_tag="KB909_000157"
     CDS             4420..4770
                     /locus_tag="KB909_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6836222.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            4993..5940
                     /locus_tag="KB909_000158"
     CDS             4993..5940
                     /locus_tag="KB909_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6836223.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(5997..7415)
                     /gene="pepV"
                     /locus_tag="KB909_000159"
     CDS             complement(5997..7415)
                     /gene="pepV"
                     /locus_tag="KB909_000159"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBB6836224.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            7564..8409
                     /locus_tag="KB909_000160"
     CDS             7564..8409
                     /locus_tag="KB909_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBB6836225.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8413..8853
                     /locus_tag="KB909_000161"
     CDS             8413..8853
                     /locus_tag="KB909_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBB6836226.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            8903..9097
                     /locus_tag="KB909_000162"
     CDS             8903..9097
                     /locus_tag="KB909_000162"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836227.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            9233..9910
                     /locus_tag="KB909_000163"
     CDS             9233..9910
                     /locus_tag="KB909_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6836228.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(10318..11007)
                     /locus_tag="KB909_000164"
     CDS             complement(10318..11007)
                     /locus_tag="KB909_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836229.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(10982..13111)
                     /locus_tag="KB909_000165"
     CDS             complement(10982..13111)
                     /locus_tag="KB909_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBB6836230.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(13159..14496)
                     /locus_tag="KB909_000166"
     CDS             complement(13159..14496)
                     /locus_tag="KB909_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBB6836231.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(14748..15107)
                     /gene="rplT"
                     /locus_tag="KB909_000167"
     CDS             complement(14748..15107)
                     /gene="rplT"
                     /locus_tag="KB909_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBB6836232.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(15160..15360)
                     /gene="rpmI"
                     /locus_tag="KB909_000168"
     CDS             complement(15160..15360)
                     /gene="rpmI"
                     /locus_tag="KB909_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBB6836233.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(15432..15956)
                     /gene="infC"
                     /locus_tag="KB909_000169"
     CDS             complement(15432..15956)
                     /gene="infC"
                     /locus_tag="KB909_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBB6836234.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(16000..16125)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            16276..16908
                     /locus_tag="KB909_000170"
     CDS             16276..16908
                     /locus_tag="KB909_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6836235.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(16910..17815)
                     /locus_tag="KB909_000171"
     CDS             complement(16910..17815)
                     /locus_tag="KB909_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6836236.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(17900..18559)
                     /locus_tag="KB909_000172"
     CDS             complement(17900..18559)
                     /locus_tag="KB909_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6836237.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            18875..19819
                     /gene="mvk"
                     /locus_tag="KB909_000173"
     CDS             18875..19819
                     /gene="mvk"
                     /locus_tag="KB909_000173"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBB6836238.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            19812..20789
                     /gene="mvaD"
                     /locus_tag="KB909_000174"
     CDS             19812..20789
                     /gene="mvaD"
                     /locus_tag="KB909_000174"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBB6836239.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            20802..21887
                     /locus_tag="KB909_000175"
     CDS             20802..21887
                     /locus_tag="KB909_000175"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBB6836240.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            21884..22948
                     /locus_tag="KB909_000176"
     CDS             21884..22948
                     /locus_tag="KB909_000176"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBB6836241.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(23197..24000)
                     /locus_tag="KB909_000177"
     CDS             complement(23197..24000)
                     /locus_tag="KB909_000177"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBB6836242.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(24020..24862)
                     /gene="kduI"
                     /locus_tag="KB909_000178"
     CDS             complement(24020..24862)
                     /gene="kduI"
                     /locus_tag="KB909_000178"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBB6836243.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(24878..25885)
                     /locus_tag="KB909_000179"
     CDS             complement(24878..25885)
                     /locus_tag="KB909_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBB6836244.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(25892..26536)
                     /locus_tag="KB909_000180"
     CDS             complement(25892..26536)
                     /locus_tag="KB909_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBB6836245.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(26636..27394)
                     /locus_tag="KB909_000181"
     CDS             complement(26636..27394)
                     /locus_tag="KB909_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBB6836246.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(27521..28672)
                     /gene="fucO"
                     /locus_tag="KB909_000182"
     CDS             complement(27521..28672)
                     /gene="fucO"
                     /locus_tag="KB909_000182"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBB6836247.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(28754..29065)
                     /gene="rhaM"
                     /locus_tag="KB909_000183"
     CDS             complement(28754..29065)
                     /gene="rhaM"
                     /locus_tag="KB909_000183"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBB6836248.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(29067..29912)
                     /gene="rhaD"
                     /locus_tag="KB909_000184"
     CDS             complement(29067..29912)
                     /gene="rhaD"
                     /locus_tag="KB909_000184"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBB6836249.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(29926..31182)
                     /gene="rhaA"
                     /locus_tag="KB909_000185"
     CDS             complement(29926..31182)
                     /gene="rhaA"
                     /locus_tag="KB909_000185"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBB6836250.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(31179..32639)
                     /gene="rhaB"
                     /locus_tag="KB909_000186"
     CDS             complement(31179..32639)
                     /gene="rhaB"
                     /locus_tag="KB909_000186"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBB6836251.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            32792..33661
                     /locus_tag="KB909_000187"
     CDS             32792..33661
                     /locus_tag="KB909_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBB6836252.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(33787..34686)
                     /locus_tag="KB909_000188"
     CDS             complement(33787..34686)
                     /locus_tag="KB909_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836253.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(34851..35675)
                     /locus_tag="KB909_000189"
     CDS             complement(34851..35675)
                     /locus_tag="KB909_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6836254.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(35686..36981)
                     /locus_tag="KB909_000190"
     CDS             complement(35686..36981)
                     /locus_tag="KB909_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBB6836255.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(36997..37476)
                     /locus_tag="KB909_000191"
     CDS             complement(36997..37476)
                     /locus_tag="KB909_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBB6836256.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(37482..38510)
                     /locus_tag="KB909_000192"
     CDS             complement(37482..38510)
                     /locus_tag="KB909_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBB6836257.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(38527..39633)
                     /locus_tag="KB909_000193"
     CDS             complement(38527..39633)
                     /locus_tag="KB909_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6836258.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(39862..42459)
                     /gene="adhE"
                     /locus_tag="KB909_000194"
                     /gene_synonym="adhC"
     CDS             complement(39862..42459)
                     /gene="adhE"
                     /locus_tag="KB909_000194"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBB6836259.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(42764..43144)
                     /gene="yajC"
                     /locus_tag="KB909_000195"
     CDS             complement(42764..43144)
                     /gene="yajC"
                     /locus_tag="KB909_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBB6836260.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(43241..44386)
                     /gene="tgt"
                     /locus_tag="KB909_000196"
     CDS             complement(43241..44386)
                     /gene="tgt"
                     /locus_tag="KB909_000196"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBB6836261.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            44604..45302
                     /locus_tag="KB909_000197"
     CDS             44604..45302
                     /locus_tag="KB909_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6836262.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(45470..48109)
                     /locus_tag="KB909_000198"
     CDS             complement(45470..48109)
                     /locus_tag="KB909_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6836263.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(48728..49759)
                     /gene="queA"
                     /locus_tag="KB909_000199"
     CDS             complement(48728..49759)
                     /gene="queA"
                     /locus_tag="KB909_000199"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBB6836264.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            49952..51127
                     /locus_tag="KB909_000200"
     CDS             49952..51127
                     /locus_tag="KB909_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6836265.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            51131..51772
                     /locus_tag="KB909_000201"
     CDS             51131..51772
                     /locus_tag="KB909_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836266.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            51769..52686
                     /locus_tag="KB909_000202"
     CDS             51769..52686
                     /locus_tag="KB909_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6836267.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            52683..53354
                     /locus_tag="KB909_000203"
     CDS             52683..53354
                     /locus_tag="KB909_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836268.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(53895..54383)
                     /locus_tag="KB909_000204"
     CDS             complement(53895..54383)
                     /locus_tag="KB909_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBB6836269.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(54584..54850)
                     /locus_tag="KB909_000205"
     CDS             complement(54584..54850)
                     /locus_tag="KB909_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6836270.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(54850..55113)
                     /locus_tag="KB909_000206"
     CDS             complement(54850..55113)
                     /locus_tag="KB909_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6836271.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            55589..55774
                     /locus_tag="KB909_000207"
     CDS             55589..55774
                     /locus_tag="KB909_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6836272.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(55916..57739)
                     /locus_tag="KB909_000208"
     CDS             complement(55916..57739)
                     /locus_tag="KB909_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBB6836273.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(58337..61042)
                     /locus_tag="KB909_000209"
     CDS             complement(58337..61042)
                     /locus_tag="KB909_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBB6836274.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(61348..62295)
                     /locus_tag="KB909_000210"
     CDS             complement(61348..62295)
                     /locus_tag="KB909_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBB6836275.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            62485..62754
                     /gene="rpsN"
                     /locus_tag="KB909_000211"
     CDS             62485..62754
                     /gene="rpsN"
                     /locus_tag="KB909_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6836276.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(62930..63292)
                     /locus_tag="KB909_000212"
     CDS             complement(62930..63292)
                     /locus_tag="KB909_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6836277.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(63303..64424)
                     /locus_tag="KB909_000213"
     CDS             complement(63303..64424)
                     /locus_tag="KB909_000213"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBB6836278.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(64440..64790)
                     /locus_tag="KB909_000214"
     CDS             complement(64440..64790)
                     /locus_tag="KB909_000214"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBB6836279.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(64920..66431)
                     /locus_tag="KB909_000215"
     CDS             complement(64920..66431)
                     /locus_tag="KB909_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6836280.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(66753..68105)
                     /locus_tag="KB909_000216"
     CDS             complement(66753..68105)
                     /locus_tag="KB909_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBB6836281.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(68258..69334)
                     /locus_tag="KB909_000217"
     CDS             complement(68258..69334)
                     /locus_tag="KB909_000217"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBB6836282.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            69530..71275
                     /locus_tag="KB909_000218"
     CDS             69530..71275
                     /locus_tag="KB909_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBB6836283.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(71555..71992)
                     /locus_tag="KB909_000219"
     CDS             complement(71555..71992)
                     /locus_tag="KB909_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBB6836284.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(71976..73349)
                     /locus_tag="KB909_000220"
     CDS             complement(71976..73349)
                     /locus_tag="KB909_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836285.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(73671..74159)
                     /locus_tag="KB909_000221"
     CDS             complement(73671..74159)
                     /locus_tag="KB909_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836286.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(74181..74783)
                     /locus_tag="KB909_000222"
     CDS             complement(74181..74783)
                     /locus_tag="KB909_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6836287.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        21461 a        16024 c        13750 g        23591 t
ORIGIN      
        1 aaataagact atactaacag tagataaatg aatgtaattg gaggaggaac acatggatag
       61 aaaaaatgtg acaccaaaga tgaaaaaaag taaaaataat agcctctggc gtaagttagg
      121 tctggggctt gttggaggga tcgttggagg actactgaca gctggcattt tttatgcagc
      181 gatgggcact ggcaacaata gttctactgc tacaagcggc aatcagaatt ctgccggtga
      241 aacagttgtg gaaaatgtca aagtcaatgt agattctgat atcaccaaag cggtagataa
      301 agttcaagac gctgtcgttt ctgttatcaa cttacaaagt caaaaccaat caagcggttt
      361 tggcggacta ttcgggcagc aagaagaaag tagcagctca gatgatagta atttggaagc
      421 ttatagtgaa ggaagcggcg tgatctacaa aaaagacggg aatactgctt atgtagtcac
      481 gaataatcac gtagtagatg gccagcaagg tcttgaagtc ttgatgaaag acggtacgaa
      541 ggtaaaagct gaattagttg gaacagatgc ttattcagat ttagcggtgt tgaagatcaa
      601 ttcagacaaa gtcgaaacag ttgcctcttt tggtgactca agtgctctga aggttggtga
      661 gcctgcgatt gcgattggtt ccccactagg atctgaatat gcaaattctg tcacttcagg
      721 aatcatttct tccttgaacc gacaagtgac aagtacgaat gaatcgaacg aaacagtcaa
      781 tatcaatgcg atccaaacag atgcagcaat caaccctgga aattctggtg gtcctttagt
      841 taatatcgaa ggacaagtta tcggtatcaa ctcaagtaag atcgcaagta cttctgaatc
      901 tacttctaat gtaagcgtag aaggaatggg atttgctatt ccaagtaacg atgtagtgaa
      961 tatcatcaat caactggaaa aagacggaaa agtgacacgt ccagctctag gtatcacaat
     1021 ggtcgactta tctgccgttt ctactcagca acaagaacaa atcttgaaga ttccttcatc
     1081 tgtaactaac ggtgtcatcg tgacaaatgt ccaaacagct acaccggctg aaaaagctgg
     1141 attgaaacaa tacgacgtca ttactaagat cgatgacaaa gaagtttctt ctggtgtaga
     1201 acttcaatct gctttgtata agaaaaaagt gggagattct gtcaaaatca cttactatga
     1261 aggctcgaaa gaaaaaacaa ctactgttga attgacgatc gatcaatcgg cattaaaaca
     1321 aaatcaaaat agtgaaaatt aataaaaaag aggttgtgac aaagacttgt cacaacctct
     1381 ttattttgga aatgcttctc cgactacggc atcctcaggc aatactaaga ttcctttttt
     1441 tgctggagca tttggcaaat gcaattcacg agcggaacag atcattccat agctatctac
     1501 ccctcgcaaa gttcctggcc agatcatcat tccatctggc atcatagctc ctggttttgc
     1561 aacgacaact ttttgtccag cttcgatatt gggtgcaccg caaacgattt gcaatactgt
     1621 accattgtct acttctgtct cagtaatcga taaatggtca gaatcaggat gtgggacgca
     1681 tgtttttacg tacccgacaa cgatcttcgg ttcatgatca gcttcaagct gttcttcgaa
     1741 tcctgcttct ttgatcaatc gattcaattt cgctaattcc tcatctgtta agcttacttg
     1801 gccgttccct tcgattgtta gatgatcgga gatatggaaa aagttccaag caacaacttg
     1861 accttgttca tctttgatcc gagcaacatt ccatttgcgt tcaacagtgt tttctgttcc
     1921 tttatcgtcg gctataataa ccatcaaggt gtctccgacg tgtgctttgt tataagcaaa
     1981 aatcatgttc tttcctccat tatcctttgc tgagatttat cttaacaaaa aattgcattc
     2041 actgcatgaa atttttttca tgctttattt ccgaagaagc ctcttctgga acaccattta
     2101 ttcgtaacaa gggactgtga caagactttt gtcacagtcc ctttactgtt ttagttaatt
     2161 gattaaaaag gtcgtacaag ttccacttgc ttaattactt ggctgttctt cttcgtcaga
     2221 aacgatcaag acatcacaag gtgaatgacg tatcacgtag ctggctacac ttcctgtcat
     2281 aaagcgttcg actgcattta gacctgactg cccaaccatg attagatcga tctcatattt
     2341 ttttggcaat ttgactgcca tggattcacg aacagaacca tatgcaataa ttccttctat
     2401 atttgtgtaa tcaacagatt tcccatattc tttacattct tcgatcattt ccttggctgt
     2461 ttcagtttgc tgatcgacta gattttgatc aataggtgca tagcccataa agttataaaa
     2521 ttgctgatcg attacgtttg ctacatatac tttcccatta ttacggcgag ccacttctac
     2581 cgcttttttg aaagcagcaa gtgcttgttc actaccgtcg atacctacta aaatattctt
     2641 atattcttga ttcatcttga cccctcctaa cagatgtcag ccttttgtta cactttctag
     2701 gaacgattcg atttcctgtt ttgttttacg atctttattc actagacgac ctaattcttt
     2761 tccgtcttgg atcacgacaa aacttgggat accaaaaatg ttccattcag cggctacatc
     2821 tatgtacttg tcacggtcta cttcaataaa ttgccaatca gaaaagtcat tttcaatttc
     2881 aggcatttgc ggtttgataa aacggcagtc tccgcaccag ccggcagtaa agaaaaatac
     2941 actctttcca gtttctacgt agcctgctaa ttcttctaaa ctatttggga taatcattct
     3001 ttgtcctcta ctttctgttt atgtattttt caattaaatt atacaccttt ctttcgaact
     3061 aacaaacatt gatcctcttt ttataaaaaa aatctggcaa aaagcaatct tttgccagat
     3121 tttatagttt cactatcgca ttattttccg tatacgatcg tatttactgt tgatttatcc
     3181 aaacctttca gtgtttgaat caacatttct cgtgcagctt caaaatcgcg aatactgaac
     3241 atcgtttgat gcgtatggat ataacgtccc actacgccaa tcactgtact tgggattcct
     3301 tcgttttgtg tatgagcagc acctgcatct gtaccgcctt ttgaaacaaa gtattgataa
     3361 gggatattgt ttgtttcagc gatatccagc aagtactcgc gcaaacgagg aagcatgatc
     3421 aaacctggat cttggatacg catcaatgta ccttctccta aatgtccgaa tgtgccattt
     3481 ttcgtcactg tatcatctgc tgcagagcag tctactgcaa agaacagatc tggcttgaat
     3541 ttattgacag aagctttaga accacgcaag cctacttctt cctggacatt cgcgcctgca
     3601 atcaatgtat gacctaatgt ttcattttgc aacgcttcta aagcttctaa taccattgta
     3661 cagccatagc ggttgtccca tgatttactg ataatattct ttccgttggc tgttttgatc
     3721 gtttcagcgt aaggaacgat tgtgtctcct ggaaggacac cgtaactcat tgcctcttct
     3781 cttgattcaa acccagcatc gaacaaaata tcggttactt ctactgattt ttgtccgctt
     3841 gttcctcgca ataaatgtgg gggaacggaa gaagaaatac atggataatt cttaccagta
     3901 gaggttttaa gtgtaaaacg ctgagcagaa acaacgtaag gattccagcc gcctagaggt
     3961 acgactttaa aaagcccgtt ttcttggatt tgtgtcagca tgaatccgac ttcatccata
     4021 tgtgctgcga ccattacacg gggtgcatcc gcttcttcat gatggcgcag accaaaaatg
     4081 ccgcccaaac catctaactg taactcatct accagcggtt ccatatgact ttccatataa
     4141 gcgcgaacat cttgttcaaa accgcttgtt ccttgtaatt ctgttaactc tttgattcgt
     4201 tgaaatgttt tttcttccat atgctattcg tctaaatttc agactaaact cctctcagac
     4261 ttatattgat ctgcggataa aatatgattt tttctgcaga ccgatcgtat ttattatagc
     4321 ttattttttc tggtagcggt tatttatttc aaagaaaata tgagagtgtg gtaaaataag
     4381 cacaaggagt aacaagtgag aagaaggagg tatgtccaca tgtatgaaga aagcgaacta
     4441 agctatttta aaggcgggtt agcagttgga atcggtctag gattattgag cggggtagct
     4501 tcaacgattt ggtatcatcg caaaaaagta ttgtcagcag accaagtact tgaaaatatc
     4561 aagtcatctt ttctaaaaga aggtgcaatc gaaggttctt ggatctcttt tgaaaaggaa
     4621 cctattagga aattcgccgt tcggtcgagt gcttatcggg gaggtctttc tcgaatagaa
     4681 gatggcgaaa ctgtttatta tgaattttta gcagatgctc atacaggaac cgtattagaa
     4741 atttcaagaa aaaaaggtgc aacagattaa tacgtcaaaa aagtgagaga acgaatacgc
     4801 acccactatt caaaagagag gtatcatgtc cttcttttgt agtgggtggt tttttagata
     4861 gagctttcca aacatatatt ccagtatttt ctttttaaat aaatgatatt tagcgggaaa
     4921 aactagcatt tcctttgatt atgaggtatt tttaatttag cttttgtttt ctatagttaa
     4981 ggagagtgaa aaatggaaca acaagaaaaa attgctgttc tgattccttg ttacaatgag
     5041 gaagcaacaa tttcaacagt cattgcagac tttaaacgag aattaccaga agcagatatt
     5101 tatgtctatg ataataattc gaccgatcga acatacgaat tggccgttca aggtggagca
     5161 atcgtaaaaa aagaacctcg tcaaggaaaa ggaaatgtga tccgccaaat gttctttgat
     5221 atcgatgccg actattattt aatggtagat ggcgatgata cttatcctgc agaagctgta
     5281 catggtttgc tcgagaaatt acgttctggt gaagcagata tggtcattgg tgatcgccta
     5341 tcaaatggaa cctactttga tgagaataag agacctttcc acgattttgg aaataacctt
     5401 gttagaaata caattactag aatgtataaa acaaaaattc ttgatgtcat gaccggctat
     5461 cgaggattca atcgtatctt tgtcaaaagt tttcctatta tgagttctgg ttttcaaatc
     5521 gaaacggaat tgacgatcca tgctttagat aaaaaattca agttcgttga aatcccaatc
     5581 gattatcgtg atcgtcctga aggcagcgaa tcaaaattga atacattctc tgacggattc
     5641 aaagtgatca tgatgattat taaaatgttt aaagattata agcctttgct tttctttggg
     5701 atttggacca tcttcttctt tttatttgga ttggtcacgg ggattcctgt gattcgcgaa
     5761 tatatgctga caagctttat tacacgcatc ccttctgcga ttttaagtac tggattgatg
     5821 actttagcac ttctttcatt agtaacaggg ttgattttgg atacagtcgt cacgaacgct
     5881 aagaaagaat atgaattgaa tctatatcat gtttatcatg aataccacag tagaaagtaa
     5941 aaaaaggatc aagactgcaa aaataatttg caattcttga tcctcttttt aattaattat
     6001 ttcgccaaac gatagatggc atctgcatag attgctgttg ctctgaacaa gtcatcaaga
     6061 ctcataaatt cgtttgcttg atgcattgta tcagtatatc ctgggaacat cgctccataa
     6121 gcaacgccac gtttcaacaa acgtccgtaa gttccgccac cgatgatttg ttcgtagcct
     6181 ttttctccag tgtggtcttc atagacttgc aataatgtag ccaccaatgg atcatccatt
     6241 ggtacgtaat gtggttccat tacgcgagca cctcgagtaa ctgttgcgcc ttcttgcccc
     6301 actgtttgtt cgatgtcact ttgcaatccg tctactgtta caccttttgg aaaacggaaa
     6361 ttcatattga tgaagttcgc ttcctctgta ccattttctt caaaagcaaa tagtccagca
     6421 ttcattgtca atttgcccat tttttcatct tcataagcga ctcctagttt ttctccataa
     6481 aaatcttcat ggacataagc agctgctaca tggataaatt gtttagcaga tcctaggaat
     6541 tcatagttat ctaagaacaa tgccaagaaa gaacctgcat tgataccaga ttgtgggctt
     6601 gcaccatgtg cgcctttacc aactaattcg atttttacat acgtattgtc cgcttcaatc
     6661 gttccgctta ctggatttgc ttcgatgaat tggtaaaatg cttcttccat cgcgatagct
     6721 gcatctgcac ttggtacttg aagtgctgca gttgctgttc ctggcaccat attttcgcga
     6781 agtccggaaa caaaagattt caagacataa tctcctgcat tgtcgccttt gaagcgtaaa
     6841 gctaaagaaa catttccttt ttcaccattg atgattggga attcagcatc tggtgagaaa
     6901 ccaaaatctg gttcttcttc atgttcgaaa taataagcca tatcgcccca gccgctttct
     6961 tcatcgctgc cgactacgaa gcgaactttt tttgatagtt tcaagtcaag ttctttaatg
     7021 atcttcatcg catagtaagc tgccatactt ggacctttgt catcgcttga tccgcgtgca
     7081 aagatctttc catccttgat tactggttca taaggatctg tgtcccagcc atctcctgca
     7141 ggaacgacat ccatgtgtcc aaatatccct agcgtttcgt ctccttcgcc aagatcaata
     7201 tgccctgcat agttatcgac attttttact ttaaatccat cacgttcgcc ataagctaac
     7261 atatgtttca atgcgtcgcg aggtccaggt ccaaatggtg catctggtgt tacttttgag
     7321 tcatcgcgct cgctgttgac acgtaaaaga tttttcaagt cttcaagcaa gtcttcttta
     7381 cgtgcttcta cttctttttg ccaatcaatt gtcataaagt taatcctcca cttatttaag
     7441 tcttcgtgtt catgatacca caaattacag aaaaaaatag ttcaaaaaat ctgacaattc
     7501 cttttcttat ctgtttttct ctaaaaaaaa tatacgctat aatgagtaaa aggaggtttt
     7561 tagatgctga taaacgaaca actagtgaaa agagtcatca cacctcgtcc aaaaatttca
     7621 cataaaggaa catttggacg tatcgttttg attggcggca atgaacaata tggcggagca
     7681 atcattatga gtgctttagc tgccgtacac agcggagcgg gtctcacgac tgtagtaact
     7741 gatgaaaaaa atcggagtgc tcttcacagt catctgccag aagcaatgat tgtagtttgg
     7801 acggatactg accagtttct ttccgtaata aagcaagcag atgtactctt gattggtccc
     7861 ggattgggta cttcttctaa gagtttggaa cgtttcaaac aagtactaga aaaccaatca
     7921 aaagaacaat ggctggtgat tgatggctct gctttaagtt tacttgctgc taatcatctt
     7981 ttgctaccct atcccgaaca aactgtactt acacctcatc aaatggagtg gcaacggttg
     8041 agttctctac cgatacaaga acaacgggat aaagaaaaca aaaagaagca acaggaaatc
     8101 ggtgctgtgc tcgttttgaa aagtcatgag acaaaaattt atggtcacca gcacttctac
     8161 accaatcctt taggttctgc tgctatggca acgggcggca tgggtgacac tttagctggg
     8221 atgatcacag gatttttagc ccagtttcct caaaatgacc aaacgattgc agcagctatt
     8281 tatcttcata gtttcattgg agaccagctg gcaaaagaac aatatattgt tttgccgaca
     8341 caaatcagcg aagcacttcc gaaatggatg aattattttt gtaaaaaatc aatggaaaac
     8401 gaggcatgag tcatggagaa atttacaggt tatgtgcgag aaccttttta ttatgaaaca
     8461 gatcaaatgg ggattattca tcacagcaat tatatccgct ggtttgaaga ggctcgggta
     8521 gccttattgg tacatctagg gtttccctat aaaaaaatcg aagaatctgg gatcatcatc
     8581 cccgttctgg aagtaaattg cagctataaa gaaatgatcc attacggaga aaaagtgagc
     8641 atccatccaa ctatccaaaa gtatacgggg acacggttgg attttagcta cgaaattgtg
     8701 ggaactgaag acaaaaaatt aaaaactact ggcagtagta aacactgttt tttactttct
     8761 gattcgcaac gattagtgaa gctgagcaaa gtcaatccgg agttagatca gttattccaa
     8821 gcgtacgctt ctttggatga tgtaaattct taataaagac cgtctaagca tttttcttgt
     8881 attgtgtcga gtagttcgta taatgaaaag aaaaaagcag gtgatcccca tgtatgtcgt
     8941 taaagtaatg cacggttaca tcgataaaac tggctgtcgc actcgggaaa aaaacttaga
     9001 caatctgctc attttcaaag acaaaaaaga atccgaagct tttgctaaaa gaatcggcgg
     9061 tcgtgtcaaa ccgatccaag aggtacgacc agattgattc aatatttttc ttttcgaggc
     9121 tctaataggc atgcctatca gggctttttt tgcagactgt gtttttatgc ccacacgatt
     9181 tgtaagcgat ttatgttata atagattata tctgcataga aaggaaggtt aaatggttat
     9241 caataatttg caacagcaag cttatgaatc tatacgtaaa caaatcattt attccgagtt
     9301 agcacctgga agtaaaatct ccgataaagt gttagaagaa caactagcta tcgggcgtac
     9361 accgattcga gaagcactga tccaactgcg caatcaagag cttgtaaaaa ccattccaca
     9421 gtccggcact tatgtttcaa aaatcgatat ccgatctgct tcattagccc gttatacgcg
     9481 ggaaaagttg gaaaaaccga tcctgcaaga atgcagtgcg aaaatgacca agcaagatca
     9541 agctaaacta gaaaaaatac tagaacaaac cgatcaggca gtaatcgctc aaaataaaaa
     9601 agcttttttt gatttggata ctgattttca ccgaacttgt tatgaaattg ctggaaaacg
     9661 agaaatttgg gattggctag aaagttatag tacgcgtttc agatggttac gtttgacgat
     9721 ttcagaatta gactggggtc gagtattaga tgaacatcag acaatgcttc aatcaatgat
     9781 tgatcataac tttgatgaag tcggatttct ttgcacgatg catttacata tgattatcga
     9841 ggagcaagaa tacgtgattc ataattaccc cgattatttt gaagatattc aggacagacc
     9901 catcaaataa gaggttttgg aatcagcgtt ttgacctgag tattagagaa agaaacggca
     9961 aaatagttcc tcatattttg ccgttttttt tgagctaata ccgagggtca gctgattgca
    10021 caccgtttat tgagaggttg tgaaaaagct gccctgcatc aagtaataag aacagccaag
    10081 taaaaatagc ttcttatgtt tttaacttgg ctggacttat taccgcagat gcaagctttt
    10141 gaacaccgtt ttccaagagg tcgtgagcct gccgttcatc tccgagtcac aaggaacaat
    10201 ttcaaaaaac agcttctcat gtttgttgaa tattttgact tgtgaccgag gagttgacag
    10261 gagaacatcg tttattcgga aaaaaaggac tgtgacacga cttttgtcac agtctcttta
    10321 tttgtaatct aaatcatact ccgtacatct tttttctatt ttttttattt cttctaagat
    10381 cccttggcta cgaatttcat tatatggcca aagtaagact gcctctaata cataaggcga
    10441 aaaatcgctt tgattcatct cttttgaaaa actcatcgct gctatctcgc tcaatgcacg
    10501 aatgtttgat tgatgtgtat aaaaaggcaa ccgccacagc acaatttttt cgctttgcgt
    10561 ataaattccc ttaacagaag cttcgatgtg gtgaaatagt tcatgtccaa taatcaaagc
    10621 ttgcgctgtt tctttagaga tcgaagctag tcctgaacat tttaattttt ctaacggctc
    10681 cgtcatcaat cgaatccctt catcttctgc ataagttgca aaagtgattc gttcgtttat
    10741 ttgctctgat tcacaggaaa cgattggaac agccatttgt tcacaaattt ctcctacatc
    10801 ggcaaaaggg tacttttttt tgatgctaca tgccgtttcg ataccacaat cgattgattg
    10861 ttgtataaga attttctgct tggacaaagg aatctttttc caaaataaat ctcgccgaaa
    10921 ctggtagaat ccccaaattt cttcggggat ctgttgtaat tcgtttagta actcttctaa
    10981 cttatgtttg tttgatattt ccggcaacga cgatcacttc ttcctccggt tccatagtag
    11041 atacttccag atccatcaaa agctgtagtt gttccagatc cgtcgctgta aaatcagaga
    11101 ctcttgctcc taagcagaga taaaattctg gtcgggcaat caattcagtt tgataaactg
    11161 ccatatcttc ccaaagttgt tcgacagctg tcatataatt ggctgcagtt gttttcatac
    11221 atgaagcatg tccacgttgg accttgataa atcctttttg atcgatgatc cgaagacttc
    11281 cagcattttt tgaacgattc tgttcgccgc atacataaaa gaaaggtgta ttttccaata
    11341 agcaaacttc atttttattt aatcgcatat cctctgcagc aagctctagt gcttcttctg
    11401 ttgtgatctc cttggttaga tcggttgctt tcacttccgt agaaccagta gcgatagccg
    11461 ttacttttga agtctgtgga tcgatttcta cgtggacttc gatcgattct ggtgtagcgc
    11521 ctgattcaat cgctttattc atcgcttcat ttttcaacga tcgtatatct tctttacttg
    11581 gcgaagggat gatacgttct acaacatctc ggaccattgc aagtgctaca ccaatagaag
    11641 aaatcacttc ggcgttttca ggaatcgaat atttcacacc cattttatta ctaaagtaag
    11701 taatcaatga ggcagcgccg ccccctacac ctacaagaga aatctgatct ttctccaagt
    11761 gatacttgtc tgccaattct aaaatcaccg gttcaatctt agcataggat ttttccatga
    11821 tctgttctgc gatgtcttca accgtcgtat gacaataatc agctaatgct tggatggctt
    11881 ttcgtgcaga tgggacattt ccataagaaa aatgttcttc ttgcactaat ccaaggacat
    11941 tggctgcaca tgtatttgta atagtcactt cttctccgtc ttccatcact accttgacgt
    12001 aatcagcagg gtctccttct ttaggagaga aaaattcaac cttaggacct ttgatttttt
    12061 ctgtctccgt aaatactgca taatctagac cggcaatatg tgcagaacgt ggaccgacat
    12121 cgatgattcc tgactgatta gcccgtacca tcgaaccgcc tgccacacct agaacccgaa
    12181 catctaatga agagatatat gttgggtggc cacctacaat tgaataatcg attgctggac
    12241 gtccattttt aatgaccccg atattggttg ttgttccgcc tacttcaaaa taaacaccat
    12301 tagacgctct caagtacatc aaagagccca tgactgatgc tgctggaccg gaaagcatgg
    12361 ttaaaacagg tcgttttttc atttcattga tttccattac tccgccgtct ccgcgcataa
    12421 tcatcaaaga aacattgacc cctgcttctc gtacggaatc ttctgtagag gttgccgtat
    12481 ctagcatttt tggtaaaata gatgcattga ttgctgctgt ccgagttctt cttgtcaatc
    12541 catataattt tgtgatgtca gaagccatcg ttgtagggat cgattttacc gatgctgctt
    12601 cataaacaac tcgttctggt tccccattat ctactccaaa tgccatagaa gaaaccaaga
    12661 cctccgctct ttctctttct aaagaagaaa tcgtttctga aacacggtct acatttaagt
    12721 gtttgacagg taagaatgca ttgacaatct ctattttttt cttattccct aaatcgatat
    12781 cgttcaatct agtttgtcgt tttgctaaaa aaccttctaa tccacctttt gccatcccga
    12841 ttacgccgac ttttgctacg tctccttcaa tcagtgcatt agtcgcttgt gtggtagaat
    12901 gtgcaacaaa cacaacatct tctggactga tattattttc cagcaaacaa ttttgaaaag
    12961 actgaacgac acctgcggct actccacgga catcatcgtg ggttgttttc actgaagatt
    13021 ttccgatgat ttcgtgcgtc gcattatcga ttgcgactgc tttcgtatgt gtaccgccaa
    13081 catcaattcc cattcgcaca aaacgtttca ttttcttttc ctccattcat ctaatcgttt
    13141 ttatcgacgt tttgtttact aggcgttccc gtacaataag aacgtgatca ggcataagat
    13201 cgctccgatg atccaaccag ttgggatgga tttcttcata tattctcgag aagttacttt
    13261 tgtataacct aatccccaag caacccaaga ttgtgtaata tctaaatgct gaggagcaat
    13321 cgttgtgatt gcaaataacg ggaacaaaaa ggctggcgac atcgttggat taacagctaa
    13381 tacgacagct aaaatagctg agcctgaacc gactagattc attggaccgc ggaaaaatcc
    13441 tagtggtgtc aatatagcaa atacgattgc caagactaat ggtgattgcg gtatccaatc
    13501 tccaaaaata gctgaaaaat aaggagaagc atacgcagct gaattattga acatcgctaa
    13561 ggtcatcaag aaaccaacca ttggcgcaac atctactgcg ccatctgtaa ataatttcgc
    13621 aaactgacga cagatttctt tataacctcc gcgcaatttt ccagtaaaca gcaatgccca
    13681 gatacctgct agaataaaac ctaagatgat tggaagatct aaaagaacga cccctaaaac
    13741 tggtaataat acggctaacc atgagatcat tggtgcgtcg ccaccttcag ctggtacgtt
    13801 tgctgccatt gcatagcgtt tctttttgtt cattgatata ttagcgaccg ttagtaccac
    13861 aactaagctt acaatcatcc caatcatacc aatttggaaa tagtcattat aagtatagct
    13921 ttcagccgct ggattgaaac cagcataaat cgtttgatat tgtttgaaat tgacgatatt
    13981 agcaaagatt ccagccataa tcgagcccat aaatgagaac agtgcaaccg gtactgaaat
    14041 acctaatgac atcaagattg gcaacacaat aactgcaata gaaatcactg gtccgattcc
    14101 tgtcatcgac atgaatataa cagcggttac aatacatagt aagctcatcg tgattcttgg
    14161 cttgtcccct ccaagttcaa ctacctttcg aatcagggta gctgcgattc cgctatctac
    14221 tagaacacgc ccgaaaaagg caccaaagaa gacatttacc aagatcgatt tggcgtactc
    14281 agctggcccc gtcgtataga tatgcgtcaa cacatcaatt actccttgcc cttccatcgc
    14341 cgggtttggt gaaaacgtgt ttccgactag cgctaatccc atccatacag tagccatgat
    14401 ggcaaagccg accatcaagt tgtagccttt tacacagtac cagaccatga aaaagaatga
    14461 gataactaac aaaataccaa taataatatc actcatgtta ttcctccgtc cattttgttt
    14521 ttctgataag caaactaata tatcagtcaa actcattcta acttatgtag ttagcgcttt
    14581 cattaaaggg tgaccataaa tgttcagttt tcaattaaaa aaccttaatt atgctatttt
    14641 agacttatac gttattgtcc tgtttcattt gatggaggat tgtaaataaa aaaagaggaa
    14701 agaacataac ttttcgttat cttctttcct ctttataatt gtttagctta tttagccaaa
    14761 gcttcttttg cttggtcagc caatgcagta aatgctgctg catcgttaac agccaagtca
    14821 gctaacattt tacggttgat gtcgatttca gcaactttca aaccgtgcat taattttgag
    14881 tagctcaagc cattcatacg agctgctgcg ttgatacgag caatccacaa tttacggaag
    14941 tcgcgtttct tttgacgacg atcgcgatat gcgtagttgt atgaattcat tacttgttct
    15001 tttgctgttt taaataaagt gtgttttgaa ccgtagtaac cttttgctaa ttttagcact
    15061 cttttacgac gtttacgagt tactgttcca cctttaacac gtgccatgta taattcctcc
    15121 taataaaaat aaatcttcag attctgttat ttgtacttct tatttcattt ttgctagttg
    15181 ttggcgaata cgtttgaagt cgccactaga aaccatgctt gctttacgca attgacggcg
    15241 ttgttttttt gttttgccgt ggaaacggtg acttgtaaac gcgcggaagc gtttcaatcc
    15301 gcctttacca gtacgtttga aacgttttgc tgatccgcgg tgtgtttttt gttttggcat
    15361 gactatattt cctcctcaaa atctttcgtt atccgactat cggctgtcca acagccagtt
    15421 agtcattcaa attacttact gtcgtttttc ggtgccagcg tcaagaacat gctgcgtccg
    15481 tccattttcg ctttttgttc cactgttgca atatccgcag tttcttcagc taagcgattc
    15541 aagacttttt gaccaatttc tttatgggta atggcacggc ctttgaaacg gatagaagct
    15601 ttcactttat cgcccttttc caagaactta cgtgcattac gaagttttgt attgaagtca
    15661 ttcaagtcga tcgtaggact taagcgaact tcttttacat tgatcacttt ttgtttttta
    15721 cgcgcttcgc ggtctttctt ttgttgttcg aaacggtatt taccgtagtc catgattcgc
    15781 gcaactggtg gtttcgcacc aggggcaact aacacaagat ccaagtttgc ttgttctgca
    15841 atattcaatg cttctgcttt tgtcttaact cctaattgct caccatctga accgatcaat
    15901 cgtaactctc gtgcacgaat gccgtcgtta accatcatat cctttgctat ggtcattcac
    15961 ctccaaatat tatgagagaa agaaaagctt accgaataaa cggcaataaa aaaacgagtt
    16021 ctcttacaga acccgcgcgt acttcaccta atagaaccag tgaaaactat ctagcccagt
    16081 gacattatca actaaggcga gaagcgggtg cttctgcttt tatttctcaa ccatcatagt
    16141 atagcaaaaa ctaatctttt tgtcaatgtt tttcatacag tttgtcttcc ttttctgaaa
    16201 atgattagat tagcagactt tctagcagtg attcccgctt ctttgctata ctaaagaaaa
    16261 acgaggtgaa cccacatgaa aaaaatcgaa cctattccac cttctcttcc tcttcttaca
    16321 aagggagagt tttatttaga agatgaggag atcttctctg gtcttctgat caacgggggt
    16381 gaccaaagct atctcgatgc caaaaatatg gtattaagag agagtcatat ccaaaaactt
    16441 acgatgcaaa aaacagtttt acgtcatttt gaatgcagta atgtcatttt tgaaaaatgt
    16501 gatttttcca atctggagtg gattggtggc agtttccacc aagtcgtgtt tcatcaatgt
    16561 aaattaacag gtacgaattt tgccgaaagt tatcttcgag actgtacttt cactgattgt
    16621 attgcttcga tggcttcctt tagtagtaca aacttgaaag ctgtctcctt cgatcattgt
    16681 caattagaag acagcgaatt ttatgaggtc acttggaaaa accttttttt gtctgacaat
    16741 cagttgaccg gttcgaactg gtttcgaact tctctgaagg gattagactt tacgactaat
    16801 ttcttcacag caatcgcttt atctcaagat tctttggcgg gactaatcgt caaccaagag
    16861 caagcacttg tgatcgccca agcccttggt ttgcagatca aagactagat caacgaatcc
    16921 gccgccacag tgcaataagc atccaaatag ataagaccaa actgatgatc aaggcgattc
    16981 cccatccgaa aacggaatgg gtaaagggta actggagatt cattccgaag aatcctgtca
    17041 caatagttgg aacggtcaag atcagcgacc agaccgtcaa aaatttcatc gtgtcattca
    17101 agttgttatt cagcaaatta ttataagtgc cagagagctg gtctaaaatc tgcgaagcta
    17161 agttcgtcat ttcaactgct tgtcgtgctt cgatcagcgc atcgtccaac tcttcttttt
    17221 ccttttctga caacttgcga taaatagcca atgccttgat ttgttctaaa agtactacat
    17281 tttgttttgt tcctgtaact aagtaaacca aaccgatctc taaatctgaa agttgcagca
    17341 gattcttgtt cgttgttttt tctcttaatt tcagattaag ccgctgacgt tcactattca
    17401 cttcctcgat taaaggaaaa aaggaatcag aaatcaaaaa caatgtacga aacaataaac
    17461 tgtatacact catgtctggc attcgttcca aaagcgatcg aattagtcga atcacgtact
    17521 cggtattcgg cgtggtaaat gtaaacaaac cgtcttcttt taaaataaaa gcgataggac
    17581 tagtttcata atgattatcg actttttgct ggtgcggaac atttgataca agcagtaacg
    17641 cttcatcaaa agaatcgtac tctacgcgcg cccgttcatt tttatctaga gaataagtca
    17701 gcatctcgtc actaatgcca tattcttctt ttaagttttt aacagctagc acatcgtttt
    17761 gctgtacatt gatccaaaaa ttacggtctt gattaaaata gtgtttttcc cgcatactct
    17821 atcctcctga catttgtttc cagtataaag aaaaaagtcg ctcaaataaa ggtttaccct
    17881 ttatttgagc aactgtaaat caaatggcta ctttggtttg gcgaatctct gctaattttt
    17941 cttcgatcat tttcaagact tcttcttttg cttgaggatc ttccacaaaa ttatagcggt
    18001 ctccatcgat ttggattttt ggactttctt tgtattcttc ataccattga tcgtaacgtc
    18061 tgttcaattc tttgtaataa tcgtatagac ttggatcaaa ggacaattgt tcatacgaac
    18121 gaccacgttt ttcgatacgc tccaacatcg tatcaaaaga tacacgaata tgaactaata
    18181 aatccggatg ttttttatgg gcagcatagg gaagttcttc catcatgttt tccagcagtt
    18241 catcatacac acgaacttct gtttctgttg ctcttcctag atctgcattt agatggaaaa
    18301 gcagtgaatc ttcataaatc gaacggtcca atacattatt gtcatctttc attgcttgtt
    18361 tgatgcttgc aaaacgttta ttcaaaaaat aaatttgcag caaaaaagca tactgttcag
    18421 ggtttgcata aaataagggc aagacttcat tatcatcaat cgattcataa aatgcctgac
    18481 tatcaaagtg ttcagccatc atttctgtta aacttgattt tccggcacca attgtacctg
    18541 ctaaaacgat cacgctcatt tacctccagc tcacttcatc actaaatatt gtgtttaact
    18601 ccaacctttt taaatatacc cccaatatct agtagtgtca attgtatttt tttctagtca
    18661 aagaagaaaa aaagtcaaaa aattcttaag aaaaaagtgt tttttcttta gaaaacgtat
    18721 tcttagtttt acttctgaga tggttttagt aaaataaagg aggaatgttt tttgagaccc
    18781 ttagtggaca aaaaaattcg tgaagcagcg caactcgttt tgggcgcttt attttttgct
    18841 taaaaatcac ttttacgtga gaaggagtta gattatggca aactatggcc aaggagaatc
    18901 aagcggaaag atcatattga tgggcgagca cgcggttgtt tatggagaac cagcgattgc
    18961 ctttcctttc tatgcaacaa aagtcaccgc attccttgaa gagctggatg caatggacga
    19021 tcaactggtt tcttcctact attcaggaaa tttagccgaa gctcctcatg cattaaaaaa
    19081 tatcaaaaaa ttattcattc acttaaaaaa acagcatgac atccaaaaaa acttgcaact
    19141 gaccattgaa agcacgattc ctgctgaacg tggaatggga tcaagcgctg cagtcgccac
    19201 agcagtcact cgtgcttttt atgattactt agcatttcct ttgtctcgtg aaatactatt
    19261 agaaaatgtc cagctttcgg aaaaaatcgc ccatggtaat cctagtggaa tcgatgcagc
    19321 cgctactagc agcttgcagc cgatttattt tacaaaaggg catcctttcg actacttttc
    19381 tttgaacatc gatgcttttt tgattgtcgc tgatacagga atcaaaggac aaacaagaga
    19441 agccgtcaaa gatgtcgctc acctctttga aacccagcct catgaaactg gacaaatgat
    19501 ccaaaaatta ggatacttga cgaagcaagc aaaacaagca atcattgaaa attcaccaga
    19561 aacgttggca cagacaatgg atgaatcaca atcacttctg gaaaagctga caatcagcaa
    19621 tgattttctt aatctattga tccaaacagc aaaagatacc ggggcattgg gtgccaaatt
    19681 aactggcggt ggacgcggtg gctgtatgat tgcattagca caaacaaaaa caaaagccca
    19741 agaaatcagt caagcacttg aagatgcggg tgctgctgaa acttggatac aaggattagg
    19801 agtacatacc tatgtttaaa ggcaaagcac gcgcatatac caacattgct ctaatcaaat
    19861 attggggtaa gaaaaatgaa gaactcatcc ttccaatgaa caacagcctt tcgttaacat
    19921 tggatgcatt ttatacagag acagaagtca tcttttctga tagctatatg gtagatgaat
    19981 tttatctaga tggcaccttg caagacgaaa aagcaacaaa aaaagtcagt cagtttcttg
    20041 acctttttcg taaagaagcc ggcctctcac taaaagcttc agtaatcagt cagaatttcg
    20101 ttcctaccgc agctggatta gcctcctctg ccagcgggct agctgcttta gcaggcgctt
    20161 gcaatactgc tcttaagctt ggattagatg atctctctct ttcaagattt gctcgacgcg
    20221 ggtctggttc agcttgccga agtattttcg gtggtttcgt cgaatgggaa aaaggccatg
    20281 acgacttaag ttcttacgct aagccagtcc cttccgattc tttcgaagac gatttagcaa
    20341 tggttttcgt tttgatcaac gaccagaaaa aagaagtgtc cagcagaaat gggatgcgtc
    20401 ggacagtcga aacatccagt ttttatcaag gctggttaga ttccgttgaa ggggatctat
    20461 atcaattgaa acaagcaatc aaaacaaaag atttccaact tctcggagaa acgatggaaa
    20521 gaaacggact aaaaatgcat ggaacgactt tagctgccca gcctccattc acttactggt
    20581 ctcctgacag cttaaaagcg atggatgcgg tgcgacaatt gagaaagcaa ggcattccat
    20641 gctactttac gatggatgct ggccctaatg tcaaagtttt agtggaaaac agccatttat
    20701 ctgaggtaca agaaacattt accaaattat ttagcaaaga acaagtaatt actgcacatg
    20761 ctggtccagg aattgcgatt attgaataaa gggagatttt tatgattgaa gtatctgcac
    20821 caggcaaact ctatattgcc ggagaatatg cagttgttga aacaggccat ccagcagtta
    20881 tcgctgcagt cgatcaattc gtgacagtca ctgtagaatc tgcacgaaaa gtcggaagta
    20941 tccaatctgc acaatatagt gggatgcctg tacgttggac aagacgcaac ggagaattag
    21001 ttttagatat tcgggaaaat ccttttcatt atatccttgc tgctattcgc ttgactgaaa
    21061 agtatgcaca agaaaaaaac attcttttat ccttttatga tctgaaagta acaagtgagt
    21121 tagacagttc aaatggccgg aaatatggat tgggttctag cggtgccgtg accgttgcaa
    21181 cggtcaaagc cttgaatgtt ttttacgcgt tgaatttatc tcagttggag attttcaaga
    21241 ttgcagcact agccaattta gcagttcaag ataatggttc ctgcggcgac atcgctgcta
    21301 gctgttatgg tggctggatc gctttctcaa ccttcgacca tccttggctc caagaacaag
    21361 aaactcagca ttctatcagt gagttacttg ccctggattg gccaggtcta tccattgagc
    21421 cattgattgc tcctgaagat ttacgtttat tgattggttg gacgggtagc cctgcctcta
    21481 cttctgattt ggtcgatcaa gttcaccgtt cgagagaaga taaaatggtg gcttatcagc
    21541 ttttcttaaa aaatagtaca gaatgtgtca acgaaatgat caaagggttt aaagaaaata
    21601 atgtaacgtt gatccaacag atgattcgaa aaaaccgaca attactgcat gatttatctg
    21661 caatcactgg ggtcgtcatc gaaacgcctg ctttgaacaa attgtgtaat ttagctgaac
    21721 agtatgaagg agccgcaaaa tcttctggtg caggtggggg cgattgcgga atcgtaattg
    21781 ttgaccagaa atctggcatt cttcctttaa tgagtgcatg ggaaaaagca gaaatcactc
    21841 cactgccgtt acatgtctat agcgatcaaa gaaaggaaaa ccgatgaatc gaaaagacga
    21901 acatgtttca ctagctaaag cctttcatga taaacaaaaa aacgaatttg acttcgtacg
    21961 gatcatccat aaccctttgc cgcaaatagc agtttctgat gtcgatctaa gtacacaggc
    22021 agttgggttt acactaagca gcccatttta tatcaatgcg atgactggcg gaagcgaaaa
    22081 aacaaaaaaa atcaaccaag atcttgcaat cgtcgcaaga gaagcagatt tgatgattgc
    22141 cactggttca gtcagcgctg ccttgaaagt cccttcttta gccgatactt atacgattat
    22201 gcgacaagaa tatcctcacg ggaaaatcat tgccaacatc ggtgcaggga cttctgtcga
    22261 aagagccaaa gaagctatcc gattgtttca cgcagatgcc ttacagattc atttgaatgc
    22321 acctcaagag ttggttatgc ctgagggaga ccgtgatttt accaattgga aagtacttat
    22381 tcaagaaact caaacagcca ttgacgtccc cctcatcgta aaagaagtcg gttttggcat
    22441 gacaagagaa acgctcaatg atctagctgc tttaggagtt catacagttg atatcagcgg
    22501 tcgaagcgga acaagcttca cccagatcga aaacgcccgt cgctccaagc gggaactgag
    22561 ttatttagct gactgggggc aatcgacagt ctcttcattg cttgaagcaa atgaagcaga
    22621 cacttctatg gaaatcctag cctccggagg tatccgcaat gcctatgaca tatttaaagc
    22681 cctttgtctc ggcgcaaatg ccgtgggtac ttcaggaacc gtactgacgc atctgatgaa
    22741 tcacggcgta gaagaaacta ttatactgat gaagcaatgg caagaagagc ttcgtctgct
    22801 ttatactatg gtcggcgcaa cgaataccgc ggccctacac caacaatctc tgatcttttc
    22861 cggaccagtg aaggattggt gcgaagcaag agggatcgac ttagtgaagt atggaagacg
    22921 cacagaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    22981 caaacggcgg aagtaaaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa
    23041 aagcaatttt cgtgaattcc ttcttatttc ttggagttaa atgcttctgt cccagcctct
    23101 tttttcgaat aaatgatgtt taatcagctg tccttcggta ttcgttcaat ccgctgattt
    23161 cacaacctct ccactaaaca gtgtactaaa gctcttttaa ggttgttttc cgatataggc
    23221 aagtatgcct ccgtccacat acaagacatg gccgttaacg aaatcagatg cgctagaagc
    23281 caagaagaca gatggtccag ccaaatcgat tggctcgccc cagcgtgctg ctggcgtacg
    23341 tccaacgata aattgatcga atggatgacg ttcaccgttt tcttgtgttt cgcgtaatgg
    23401 agcagtttgc ggtgtagcaa tataacctgg tccaattcca ttacattgga tattgtattg
    23461 accgtattca gaagcgatgt ttttcgtcag catttttaat ccgccttttg ccgcagcata
    23521 agcactgacc gtttcgcgtc ctaattcact catcatggag cagatattga tgattttacc
    23581 gccgcctttt tcgatcatat ccggaataac tgcttttgaa acgatgaatg gggcatttaa
    23641 atccacgtcg attacttggc ggaagtctgc cgcatccatt tcgatcatcg gtgtccgttt
    23701 gatgatccct gcattgttga ctagaatatc aactgaacct acatcttctt tgatctgttg
    23761 aaccatcgct tgaaccgctt cttcatcggt cacatcgcag acataacctt ttgcatcgat
    23821 gcctgcttct ttataatgcg ctataccttc atcaactgat tcttgattca agttattaaa
    23881 tacgattttt gctcctgctg tagctaaaga gcgtgcaatc tcaaatccaa taccatagac
    23941 agcaccggtg actaatgcta cttttccatc taaacgaaac atatccatac taaattccat
    24001 cattttctct cccttatgct tattttaatt gatccatttg caccatatcc atgtctgtat
    24061 aggtgatatt ttctccgcac attgcccaga tgaatgagta attgcttgta cctacacctg
    24121 aatggatcga ccagcttggc gaaataatgg cttgttcatt gtctacaact aaatgttttg
    24181 tttcatctgg tttgcccatc atgtggaaca cacgtgtatc ttcattggca taatcaaagt
    24241 agacataagc ttccatacga cgttcatgtg tatgacaagg catcgtattc caagcgcttc
    24301 ctggttctaa aatcgtataa cccatttgta attgacagct ttcgcataca tttggatgga
    24361 tgtattggta gattttacgt tcattcagtg tcaggccttc accagtctcc attggtttta
    24421 cttggtcgat actgattttt acatttggat atttatgatg agctggaaca gaactaatat
    24481 agaatttagc tgggttttca gcatcttgag aagaaaatac aacatgtcgt gtttcttttc
    24541 cgatatagta tccgtcttgt tttttcattt cttctttttg cccatcgatc tcgatgaatc
    24601 ctggtccacc gatattgatc acacctagtt cacgacgctc taagaagtaa tcaacaccta
    24661 gttctttgtc taatgtgatt tctaattctt tttcagtagg tgtcactcca ccaaagatca
    24721 ttcgatcgtt gtgcgtataa gtcaaactga ttttccctgg ttcaaatacc ttttctacta
    24781 aaaattcttt tctcaattgt tccgttgaat aatgacggat atcttctgga ctgtgtgtat
    24841 aacgtgtttc catttcttgc attttcttct actccttcta tcgaatgatt tttccagagc
    24901 cgcatgctaa aaattgtgcg acttcttctt gactaaattg gttgcagtcc ccatggatcg
    24961 tatgcttcaa ggcagaagct gccgtagcaa aatcaatgat ttcttgcgga gacatattgg
    25021 ataaaatccc atggagcacg ccacctgcaa aagcatctcc gccacctact cgatccacga
    25081 ttggggtgat tctatggact tgggattcca catattcatg gttcatccac aatgtcccct
    25141 tcaattcatt ttcacttgct gaatgaacgg tacgcttggt cgaataaaac acctgaatat
    25201 tcgggaactt ttcctgcatt ttttgataat aataaattag aggttgttct tctgcttctg
    25261 gcgctttctc gatacctaac aaataaagag catccatttt tccagctgag cagatatcta
    25321 ctaaaggtaa aagctgatgg attacttcgc tggcttcttg ctgtgtccat aattttccac
    25381 gatagttgat atcgaagctg atcaggcagc cagctttttt tgcagcttct atcacctgtt
    25441 tcgtcatttt ttgccatttt ttagacaaag ctggggtgat tcctgaaaca tgaaatatat
    25501 ctattccttg gaataactcc tctagcgacc attccaaatg atccatttca gcaaaacttg
    25561 atccggcacg atcatagatc actgaggcgg cgcgttcgcc actaccagtt tccatataat
    25621 aagtacctag tcttgatcca ccagataata cctgtttcgt atctactcca taacattgca
    25681 agtgcttttt gactgctttt cccaatgcgt tatcaggtac ttttgtagca aaaatcgctt
    25741 catgtccgta attagctaaa gaaattgcta cgtttgcttc ccctccgcca taatgggcag
    25801 cgaatcgttc acttgaatcg atacgggttc cctgctctgt ggacaatcgc aacatgattt
    25861 ctccgagtgt cactactttt cccataagca gctacctctt gatttctttc atttttgctg
    25921 catactgttg cgcgacttcc gttactttgt caaaatctcc tgtagctgcg ggtgctaaaa
    25981 ggttcccacc tactccgact gttacgacac cagcatcgaa ccactctttc atattgtcca
    26041 gactcacacc gccagttggc atgatattga cttgaggcat cggcgccttg aaggcagaaa
    26101 tgatacttgg tccataagcg cttccaggaa atagtttgac gatatctacc ccgcttttca
    26161 gcgctgtttt gatctcggta atagtcatac atcctggtaa gtaaggaatt tgatacagat
    26221 tgcacatctc tgccgtttct tgatcaaagg aagggctaac aatatactct gcgccagcta
    26281 agatagccaa gcgagctgtg acagcgtcta atactgtgcc tgcgccaatc actatttctg
    26341 gttggtcttt gtagaatgac aaaagttctt tgattacttg atctgcttga gggactgtaa
    26401 aagtcaactc aataccagtt agaccacctt tgatgattgc gtggcaagca ttcaaagctt
    26461 cttctttgct ttttccgcgt accaccgcaa tcactccggc gtttttcaat cgagataaaa
    26521 tatcaatttt tttcatcttc tccacctatt tcctatttag aaattttatt ttataacttg
    26581 gaaatctata cccatattat acggcagaaa agaaaaattg caaacgcttt tttcattatt
    26641 tttgaattct ttgctcgatt tcgctttttg tttgcttgag ggcactgatt atttgttctt
    26701 ttgtctcatc tgttaaacga tatttcggca tacttacact aaatgcacca atgatttgtt
    26761 cgtttttcac gattgaggct cctatacaaa aaatatcacg ttcgatttct tcatcgtcaa
    26821 atgcgatgtg ggtttctttt accgttttga tttccttttt caaccgtaat gcattggtga
    26881 tcgtatattc tgtgtaaggg atcaacggat gcttttcaag ataatcagtg tactgctctt
    26941 cactgaattc tgctaatacg gctttgccca tcgcagaatt gtataatggt cgggtgattc
    27001 cgatttttga agacatgcgg atcgtttgat gttttggatc tagtttgttc acgtacaaga
    27061 tctcattgtt gtccaatacc cctaagtgga tagtctcatc gatcttttgc tgcagctgtt
    27121 ctaaaaacgg taaagtcaac tctaccaaat cgatttgttc aatgttttta ttcgcgtagc
    27181 gaataagctt tgcacctaaa cgatagtttt tctctgaatt tttatttacg tagccgatca
    27241 tcaacaaagt atctagtatt ttcaagactg tagaagaggt cattcccaca ccctttgcga
    27301 tcgtctgcaa agagacatct tggttttccg ctaaatagtc tagtatttta gaggctttga
    27361 tcaatacagt tccataaggc tttttatttt ccatataata ttctcctatt tctttataag
    27421 aaaaattata gcggaaatac catcaattta aaagagatat ccagatataa actaccattt
    27481 ctctttacag gcaatttaat gttgaagatc cgcttcgttt ttacatcaaa ctttgatata
    27541 aagcaatgat ttcttctact gtcgtttctc ttggatttcc tggtgtgcat acatctcgca
    27601 aagcatcttc tgcaattgct ggaatatctg cttcttttac acctaattca gaaatggttt
    27661 ctgggattcc aaccgctttg ctcaaccgat cgatctcacc acaagccgct tctcttacat
    27721 cttctaaaga catttcagct gctcctttaa tccctagaac aagagcgatc tcacggtact
    27781 tttctccagt atattctttg ttatatttca tgacagttgg caaaagtgct gcacacgcta
    27841 cgccatgagg aatgttgtac catgcactta acgggtgagc catcccgtgt accagtccta
    27901 aaccgacatt tgagaagccc attcccgcaa tatactgtcc taatgccatt ttttctcgcc
    27961 cattttgatc gccatctaca gaagcttcca aagaatggcc gatgatttcg attgctttta
    28021 aatgcagcat atcagtcatt tcccaagcgc cttttgtgat aaacccttca atagcatgcg
    28081 tcatagcatc catacctgtt gatgcagcca attttttcgg cattcccatc atcatatcgc
    28141 tgtcgatgaa cgcgacgatt gggatatcat gaggatcaac acaaacaaat tttcggtgat
    28201 ttacttcatc tgtgatgacg tagttgatcg ttacttctgc tgctgttcca gaagtcgttg
    28261 gtatagctaa tataggtaaa catggatttt tcgtatcagc aacaccttct aaactaatga
    28321 cgtctgaaaa ctctggattc gtcaaaataa tcccaatggc ttttgccgta tcgattggcg
    28381 aacctccacc gattgcgatc aaacagtctg cctctgcctc tttaacaaaa gccactccat
    28441 cttttacatt ttggatcgtt ggattaggta cgatcccgtc gtataaagca taagcgattg
    28501 ctgctttatc tagaagttct gttacttttg ttgctatacc gtgctcgatc aatcctttgt
    28561 cagtaatgac agctgctttg ccgaatcctc gctgctgaaa ttcagggacg atcgactcaa
    28621 tcgctccttt tccaaaatac gatgtttcat ttaaaatcat tcgattactc attttctatt
    28681 cctcctaatt tgtattattt ttcacaataa aaacgaaaga accccaagca accggttgcc
    28741 cagttgcttg ttgctacagt tcaaagactg gcatcaattc ccaactgact ggagaggcat
    28801 ctggatttgt ctccatgata tcttccatgt acttccacca tttttgattg atagatgtat
    28861 ttgccatttt ttcccataac ttttcatctt cgatcactaa gtaaccaaat aacaaacttg
    28921 tactcggatc aagatagatc gaatagtcga tgaccccgtg ttcacgaagt gctgtacgca
    28981 tttctggcca aagttcatca tgtctttttt tgtattcttc ttgtttttct gggtaaactt
    29041 tcatgcaaaa agcttttttc accatgtcag acacctgctt tcgtatgaac ttcctccaaa
    29101 taacctgctt ttggagtgac accaaacgca tctgctaaat gccacaggtt ttcgtccgtg
    29161 attgtttgca agattggtcc ttgcgctttg acgtacgtat agacttctgc tgccttttct
    29221 gctgtctcga tcaaaccaaa gacttcatcc atgtcttttc ctgacccgta gattccatgt
    29281 tgtggccata aaaccaatcg agtttctttc attttttcag ctgttgcttc cccaatctca
    29341 tttgttcccg gaaccatcca cggaatgatg gaaattcctt ctggaaaaac aactaagcat
    29401 tccgtacaca tttgccatag cgtacgacta aaggaacgtt cgtctaattc atgcgtaaaa
    29461 ctcatcgcta atagatgact agcatggcaa tgcataacga tccgattatc tgggtctact
    29521 tctaaacggg cgatatgact catgaaatga cttggcaact cgcttgtagg aaggcattcg
    29581 ttttccagcc cccacaaaag ttccagtgtt ttgccatctt cagcaactcg aacgattcca
    29641 agattctcgg caggttcgct cgctacattt ttaaaatatc ttcctgaacc agttacaata
    29701 aaatagcatc ctgctaaacg gctggcatca aaaatcatcg agatgcggcg gatcactttt
    29761 tcaggatcca agaacggtgt gatctcttct tcttttagta aataagaaat attcccgcca
    29821 tttctttcat cccatcccaa gcgataaaga ttcgacgtcg tttcgatcat ttctttcaca
    29881 taaggcgctt gtaaaatatc tatttttttc aatatagcca cactcctatt ttcttaattc
    29941 caacacgtct ttttgatatt cctggacttc ttccagccaa tccaaaccaa ctggaacttg
    30001 atttttgtaa cagaaataat tccatacatc ggcatacggg aaatctttca attcttccgt
    30061 ataagccatt cttgaagtaa agtcaaaagc cagctccatt tctttcaatc gctcaactgg
    30121 ttccagcata gctttcagca gtgctttttg tgtatttctc gtaccgatga cccaagcagc
    30181 gatacggttg atcgttgcat caaagaaatc cagaccgata tttgtttttt ccaacaattc
    30241 gttacggact aattctttag cgatttcctg caattcatca tccatcaaaa ccacatggtc
    30301 tgaatcccaa cgcactggac gggaaacatg caacatgatt cctttgctga ataaagctaa
    30361 tgaagataat ttattggaaa tcacttctgt tggatgaaaa tgtccagcat ctagacaaac
    30421 aagtttgtca cgagtcaacc cgtaacccat ataaaattca tgggaaccga ctgtataagc
    30481 ttcagcgcct aaaccaaata gtttgctttc tactgcatct tgtacatacc gttcatctaa
    30541 ctcttctgta aaaatttcat cgagtgattc cattaaacgt tcccgtgggg taaaacgatc
    30601 aatcggatta tctttcatcc catcaggtac ccaaaagtta ttgatacttg tttgcccagt
    30661 ttctttccca aagtactccg cgattttgcg gcttcttttc ccgtgttcga tccagtattc
    30721 acgaacttct ttatctggat gagccaatgt aaagccgtct ttcatcattg gatgcgaaaa
    30781 gaaagtcgga ttgaagtcaa gaccgatttc ttcttttttt gcccactcta cccatttttc
    30841 aaaatgtttc ggctcaattt catttagatc gacagattct tctgtatcca aatagatagc
    30901 atgaaggttc aatttgtgtt tgcccggtat caacgaataa gccttctcca gatcttgtct
    30961 aagctcttca ggtgttcgtg cggctcctgg aaaattccct gtcgccatga ttccaccggt
    31021 caattcgcca tccggtgtca agaaaccttt gacatcatct ccttgccagc aatgcataga
    31081 aattttgatg tcctgtatct tttctagtac agcatctgta tctacaccga tagttgcata
    31141 tttttctttt gcttgttcgt aatttctttc aatcgtgttc atacgattac tcctttgatt
    31201 ttattcacgt accattccat cgtgttttgc ttattttcat ctgggtaaaa agtttcacat
    31261 ggaaacgact gtttgattac atttcttgct tgttctatat tcgaaaactg acctgtactg
    31321 agcatttgca tggcaacatt cccgattgct gtggcttcac taggtcctgc ttctacaatg
    31381 attccggcat aatctgctgt caattgattc agtagacgat tattcgatcc gccccctacg
    31441 atgtgcagct tttccaattt cgttccagtt aagtgttcta ctttgatcag ctcttgtgcg
    31501 taacaaagag caagattatc atacacacaa cgagcgatag ctcccgatga gacagggact
    31561 ggctgctctg tttcaaaaca gtattgctga atctcttcta tcatatttgg gggattcaaa
    31621 aatcgagggt cattgatttc catcacttgc tgcagcggtt tttcttttgc agcaagctct
    31681 gccaattccg cataactgta ctcgtactct tgcattcggg caacttcctg gatcaaccac
    31741 atccccatga tgtttttcaa aaaacgcacc gtgttatggg caccccattc attcgtataa
    31801 ttttcagaaa aagcattgcg agaaacattg gcgatctttg tttcaatccc taaaagcgac
    31861 catgtcccac tgctgatata accccaacgt tctccttgac ctggcgttcc taatacagct
    31921 gacgccgtat catgacttgc tactgtgata aaggtcacat ctggcaaatc atattttgaa
    31981 aattgttctt tttgcagatc tcctagtatc gttcccggct ctgtcaatgg tggaaataat
    32041 tccttcgaga caccgatttt ttcaagaagt tctatttccc attcttttgt ccctgcattc
    32101 agcagctgca tagtagatgc attagttttc tccgtcacca tgttaccagt aaagacatac
    32161 cctaaataat caggtatcag taacaattta tgtgcttttg ccaaattttc tttttcttca
    32221 gcaaacaatt ggaacaaggt attgaaaggc tggatctgaa tccctgtctg ctcatacaac
    32281 ttatctagag aatagatttc agaaaactgt tctactgctc cattggtacg cttgtcccga
    32341 taagcaatcg gatcatttat ccgatcccct tgttcatcaa tcagacagta atcgactgcc
    32401 catgtatcga tccccgcaaa aaggcgatca atccctgtct gctttaattt ttcaaatcca
    32461 atcaaaatct ctttgataag ataatcgatc ttccagcgat cgtgaccgtc tttgttccga
    32521 aagccgtttt tgaaccggtg tacttcttcc aagatcaaag aaccttttgc atccctcgta
    32581 cttttcatta gtcgtccgct tgatgcaccg atatcgatgg caacaaatgt tggattcatt
    32641 tctccacctc ttttacttta ttgttgatta gcactttatt aataaagcgt tatcatttat
    32701 tgacaatgct atcataatac agaatcttat attttgcttc acactatttt ggtatataat
    32761 tgcattatct tgacaagttg ggagtgttta catggattac tgggaaaaag ccaaccactc
    32821 atggtcggaa gactcaaaaa gagtgatctt gacgcctaca caaagaagca ggaatttatt
    32881 tttttatatc caagaaatcg gttacttcaa agcaccaatc ccttactata ctgaacgagc
    32941 acatttacct tcttacttga taaagtttac tttgtctggc aaaggttcgc ttacatataa
    33001 tgataatcag caacagctaa aagctggaga cttatttttt attgactgcc aagaatatca
    33061 gcgttatcaa acgatcagcg aagaaccatg ggaaatggat tggatccatt tgaatggtca
    33121 gaacgtccaa tcattttatc aggagttcac aaaagacggc cataacacct tccattcaac
    33181 aggagatcca tcagaaaaca agatccacca tttgatcaca gaattgatcc acatgcaaca
    33241 aggcacgaat gcccgtaccg atttccagtc ctctgtagct atccacgagt tgctgaatga
    33301 actgattttg caaaagtatc agctagattt cgaagaagag gatattcccg cctacgttta
    33361 caaactgaag caatacttag acgaacattt caaagaaacg attacacttg atcaattaga
    33421 acaacaattc ttattgaata aatatcagct gagcaaagat ttttccaaat ttatcggttc
    33481 tccaccaatc gattatttga tcagcaaaaa actttcttac gctaaagacc ttcttcggta
    33541 tacagaattt acggttcgaa tgatttccga agaaataggg attgagaatt ttgcttactt
    33601 tagccgcctg ttcaaagcaa aaacaggact atcgccgaga gactttcgta aattcagctg
    33661 attcatataa tatgtacgtc attttttcaa aatattttga aatatataga taaaaataaa
    33721 ataaccgcag tttctgcttc tatgtaaaca acagcagcta ctgcggttat tttttagtga
    33781 tcattctcat tgttcatctt caaaatgttc ataatgaacc aactgtttct gtgtatcacg
    33841 tttcaaaaat tctttaggcg ttatgccgaa ctctctcttg aatgctttca gaaaatgcgg
    33901 ataagaagaa aaaccacttt tactatatac agcactagag ctgcggtatt ctcgcaacaa
    33961 gtgcttggca tagatcagct ttttcttcat tacatactga tgaaacgtaa atccagtgta
    34021 ctttttaaat tctcgtgtga tatggtattt gctgacaaaa aactgctttt ccatttcctc
    34081 taaagaaagc ggatgagata aattttttga gatatattgt aacatttgtt ccacacgctc
    34141 attaggaact acagcattct gttcttgcgc actctcttct ttttgtacaa cttgattgag
    34201 aaaaatcaag tattctacca gagcttgttc atattttatg tcttcaccgt aaattttttt
    34261 atcaggagga tggtcgataa atgataattt ttgcttcaat acttcctgtt ctatttgcaa
    34321 tacacgactc ctcttctctc ccattggttg aaaacaagcc gatagattag accatggcgt
    34381 ggaacgactt tctagaaaag aaggggtgac aaagatatag acacgctcga atacatctga
    34441 agattggcgg acgatacgat gcaaatcatt ggaatggatg agcagcacac ttcctgcttt
    34501 gatcgtaaat tgtcgtccgt tcaaataaaa agtcgcttct ccctttaatg tagcatggat
    34561 ctcatagaaa tcatgatgat gatagatcgt tttattttgg ctgacgacat ctttgacatg
    34621 atagatttca tactgatcag aaaccatcgt attgacttgt tcaccgctga ttttcttttg
    34681 gagcatgtgc cgcacctcct tttgttcact tatgcacaat tttattatac cacgtttttt
    34741 gtaatcaaaa agagctgctt ttatatactc ttataaaaaa gaagagacgt ggcatcttct
    34801 agccccgccc cctccattct aaatattagt taaccaacgt cttctttaca ttattcaaga
    34861 agacttcttc cataacgaat cccatcatct tttgtttctt caagaaccac atacaggtac
    34921 ggacgattct tcatgatgat ttctttgatt tttgtgtact cgatcacacc gtctcccaaa
    34981 tttaccggca cgattttttc ctgttcgaca cgaaaatctt tcaaatgaac cgcacatatc
    35041 ttttcaccaa aacgttcaaa agcttcttct accaattgga cttgttcttg ataatcacta
    35101 cttgtgatca aattggtcgg atctaaaatg attcctagat agtccgaatc tactgcttgg
    35161 atcagctgct ctacccttgc taaagaatac accggatgat tcaaacctgg ttctatcccc
    35221 accatcattt ggtatttttc tccagctttt accaagcgac ggataacgga cacagcttca
    35281 gcaaatgctt catctgtgaa attttcttcc gtatattgga tttccggcaa aacacatcca
    35341 gtttccgaag caaccatcga cgcaccaaag gaagaagcat agcgaagata ctgctcgaac
    35401 tttgtcagca actcttgtcg tatcgttaaa tctggatgaa tcatattgat atagcaactt
    35461 aaaattccta cggtcacttc ttgcttttct aaaactcgtt tgacataatt tcccatccca
    35521 gaattgatct catttgcgcc agaaggtatt tcaggaaacg aaagacctaa ggcgagctgc
    35581 agtgtatgaa tcccttgttc ttttgttttt tctgcaagat cttctatcgt ttggacttcg
    35641 gaaagatcat gtcctctaat tgtaatgttc aacataacta ttctcctaac tcagcatatt
    35701 gggtagccac atgacgattt gcgggaagta agtaatcaaa aacaagacga ctaagataac
    35761 cccataaaaa ggaagaagcg gtttcagcat tgcctctgct tttacgcctc ctacacttgc
    35821 accgacatat agtcctgtac ctactggcgg cgtgatggag cctacacaca gattcatgat
    35881 tgaaaacaac ccgtaatgta caggatcaac ccctacactt gtgacgattg gtaaaaatat
    35941 tggtgtaaaa atcaagatag caggcgccac atccataaac atacccacca gtaataacac
    36001 aagattgact aataacagaa taataaattt attatccgtt acgcccataa tcaacgaact
    36061 aattgcctga ggaataccgg taaacgccat ggcgaaagac atcatggaag aagtagccaa
    36121 taagaacatg atcgtccctg acattgctac tgattgaaac aacatattag gtatatcttt
    36181 tagttttacc gttttatagt aaaacatagc aatcaacagg gagtaaatga cagctatcgc
    36241 tgaagcttct actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa
    36301 tagaaggcta ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc
    36361 gacaacaggg tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc
    36421 ccacaaagcg cctacgagat aacctcccat aaacaaagca gagatcgaag caccaccagc
    36481 aacaagtgaa tacatgataa aagcagtact tggaggaatg accatacctg tcggagctga
    36541 cgcgatattg accgctgtcg caaacttccg gtcatatcct tcttccactt gctgagggat
    36601 caacactccg ccaatcgcgg tagaagcggc aatggccgag ctagagatgg aaccaaataa
    36661 agcattccct aacacattcg tatgagccaa agcccccggc acgcgcccga cgaacaacat
    36721 cgcaaaatcc actagtttct tagctatccc tccattattc atgataatgc ccgagagaac
    36781 gaaaaacgga atagcgatca gcgaaaaact attgatactt cccaccattt tttgagctga
    36841 actaaaagca gaaacatcaa acggtataac taacaataaa gtcatcatcg atgagaatgc
    36901 aatacttata gcaatcggca tccctaatac aagcaacaca acaaatacaa aaaataacac
    36961 taatccggct tctattgcca ttttattcct ccatttttat attttttctt gaattgctgg
    37021 cttgttgctt aatgtatcga ttagattgat caggctatag ataatgatga gtacccccga
    37081 tacaggtact gacagataaa catatcccat aggaatactt aaagaaggcg agatctgccc
    37141 cattgtcaat gtgacagcat tccatccgcc atacaccatg atcatcgcag caaataccag
    37201 aaataaactt tgaacaacaa cttctaaaat tttacttttt ttgccagtta atttttcact
    37261 taaaaccgtt acggctaaat gtgctttttg tcccacaaca tacgcggaag acaacatggc
    37321 aaaccagaca agaccgaatc gaacaagctc ttccgtgacc gtatttggat ttcctaaaac
    37381 cgttctggaa aatacttgcc ataaaacaac agcgaccatc ccaacaagca aaacagctcc
    37441 caggatctct aataccttgt ttaaaatcat tttcatcaca gctacgctcc ttgctcttgg
    37501 atcttttgat aaaggtcttt gtaggtagga tcgtttttga atatatcatg aagtggggca
    37561 actgcctctc gaaacggtgt attatctaca tcattgaatt ggactccatg ttcttcttgt
    37621 gctaaagctt tttcttcttc aattgctttt gcaaaagctt caatttcaaa aaccgttgat
    37681 tctttcgctg cttcttcaat ggctttttcc tgctcatcag ttagctgttc tttgatggca
    37741 tcattcatga tgatgatatc tggcacacgt gtatgctcat cataggaata gtatttagcc
    37801 acaccaccat gtccagctgt atacaagaca aattcattgt tttctgatcc gttgatcaaa
    37861 ttggattgaa gagacgtgta cacttcatca cttcccatag gtacgggcga accgcctaaa
    37921 agctctacca ttttgatagc ggtttcgctt tgcatcacac ggatcttctt tcccttcaaa
    37981 tcttccggcg tatggatcgg accgtctacc atataaaagc tgcgctgacc agaatcataa
    38041 taggtcaatc cggtaaatcc taaatttttg gtcgattggt agattggctc cattatttct
    38101 tcattatcca tcaccttaaa gaaatgttct tcatcattga atagataagg aactgaaaaa
    38161 atcgaataat ctttagagaa actttccaac gctgaggcac ttacttttgt gaaatctact
    38221 gctcctgact gtgtcaattc gatcagttca cgttctccac ccagttgtcc atctgggaaa
    38281 tactggatct gtacggaacc atctgttttt tcttttacta aacgcccaaa ttcattcatt
    38341 gcatcaatta ctggctggct gttgcttgca taagcaaagc gcaaggtaac tatctcattt
    38401 acatctgcat ctgcgacagt tgccacacta gaattatttc cgcagccgct tagacctagc
    38461 agacctaggc taagcgaact tgctgcaaac agcagtgatg tttttttcat atgggtttcc
    38521 tttcttttaa caataagaga cgagcaattc tgtcaaacaa agcaccgtta acgactgtcc
    38581 ataaggcatt gctgtgattc cgatattccg ataaaaatct aaactgtccc ccattcctgt
    38641 cccgattgaa acgttttgaa cttctccttt ttcatcgatt tgttcaagca atccttggat
    38701 agcacgataa gcgacttctt tatattcttg tggtaaataa cgtttatgga ccgctttcaa
    38761 aataccgtaa gcaaatcctg cagttgcaga agattctacg taagaagaag gatcatccaa
    38821 caacgtatgc cataaaccgc tttcagactg ataagttttt aatgcacgca cttgtgcttc
    38881 aagtgtttcg atcaataatt tgcgcaatgc atcttctttc gataattcta agatttcaat
    38941 gatctctgga atagcaatcg tcaaccagca gtttccacga gcccaaaatg cttcggcata
    39001 gttatgattt ccttcaaacg tccagccgtg ataccacaat cctgttcgtt tatccatcaa
    39061 gtatttgata tggatcataa actggtaacg agcttcttct aaatattctg ggcgattcaa
    39121 cagtttcccg atttttgcca aaggaagcac tgtcatcatc aatgtatcgt cccacaactg
    39181 attcttattt tccggtccat atgtggcatg ctgtaacccg tcttcatttg tccgaggcat
    39241 gtcattcatg acccattctg cccattgttc taaataaggc aaatagcgtg aatctttcgt
    39301 gtcttcatac aagtaagcca tagtcaatag cggtgccatt gtattgacgt ttttgggcgg
    39361 agcgccttct tccatacgat cctcaaacca ttcattgacc acttgataag cgcgaggatt
    39421 ttttgtcatc tggtaatttt tataaatacc atatagaccg acaccttgtg gccaattcca
    39481 cactgtccag cttttgtcat ctactttcag tccatcaaag tccaacaaaa attcaccatt
    39541 atcgtctttg atcgttgtca ggttttcaac gagcaggtca attttttctt tcactaattc
    39601 tttaggtaca aaaatctctt ctttaataat catctttacg ccaccttttt aaacgctttc
    39661 attttatatc cttaatatag cagtaatacc gtccactata aatatcgctt tttgaacaaa
    39721 aactgtctaa aattgaccta aatgttaaat aacaaaagta actttcagtt acttggaaat
    39781 taaaaaaaga acttggagaa acaacgtttt ccaagttctt tttcatctat tttcttatct
    39841 tttttctacg ctttcttttg cttatccgtt gtaagcatca atgatgatct gtttcaattc
    39901 agagatcaat ggttctttcg gattagctgt cgtacattgg tcttcgtaag ctaattcagc
    39961 catacggtct acggttgtat ctagtgtttc ttgtgtgact ccttgagctt ttagactcat
    40021 gttgatgccg acagattttc ctaattcata aacagccgtt gctaaagctt cgactaattc
    40081 ctctgttgtt tcgcctttca gacctaagaa ttttgcgata tctgcgtaat ctgtatctgc
    40141 acggaaatag tcatatttag ggaacatcgc atgtttttgt ggatcttttg cattatagcg
    40201 gataatatgc ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt attccccgcc
    40261 gattttatgt gcgactgagt gacaaatacc taggaatgcg ttagcaaacg ccataccagc
    40321 cattgtagaa gcgttgtgca ttttttcacg tgattccata tcaggtgttt ttactgattt
    40381 ttctaaatag tcaaagacta acttgattgc ttgtaggctc aatccacgtg tataatctga
    40441 agccatgact gaaacatagg attcgattgc atgtgttaac acatccatcc cggtatctgc
    40501 tgtgacagat gctggaactg acatgacgaa ttgaggatcg acgattgcga catctggcgt
    40561 caatgcataa tctgctaacg gatatttcac atgtgtttca ctgtcagtga tgaccgcaaa
    40621 tggcgttact tcagaaccag tccctgatgt tgtcgggata catacgaatt gtgttttttc
    40681 tggtttgtcg atcttatatg tccgtttacg gatatccaag aatttttgtt ttgcaccaaa
    40741 gaaagatgtg tctgggtgtt catagaacat ccacattccc ttagctgcgt ccattgcaga
    40801 accgcctcca agagcgatta ctgtatctgg cttgaagtct gccatcagtt tcgttcctgc
    40861 gtatacggta tttgtcgatg ggttcggttc aacatctgag aagacttcga tcttcacatc
    40921 atttttacgt cgtgccaata cttcacgaac tgtatcgcag taaccgaatt ggaccatacc
    40981 agggtcacaa acgatcatga cacgttcaac gttttccatt ttctctaagt acaatagaga
    41041 gttcttttca aagaagattt ttggcggtaa tttgaaccat tgcatgttat ttctccgttt
    41101 cgctacagtt ttgacattga ttaagtttac agcagagacg ttacgagaaa cagagttctt
    41161 accataagaa ccgcatccca aagtcaatga cggaatcatt tcgttataga tatcaccgat
    41221 gccgccttct gcagatggtg tattcactaa aatacgacaa gctttcattc gaagaccgaa
    41281 tttgacatgc aactcttcgt tttctgaatg gataactgct gtatgtccta atcctccaag
    41341 attcaacata ccttcacaca aatcaaacgc atggtccgtg ttgttagctt tgatcatggc
    41401 aagaactgga gaaagttttt ctcttgatag cggataatct gggcctacgc cttccaattc
    41461 agcaatcagc attttcgttc cttttggtac actgattcct gccaattttg cgatttccat
    41521 cgcagaatgt ccaacgattg atggattgac cgcatatttt ccttcgttca tcactgcatc
    41581 ttctaatttt tgcaattcat ctggttttac gatataaact tggtgtgctt ggaattctgc
    41641 ttttactgct gcatagattt ctttatccac gatcacagct tgttcagaag cacaaatcat
    41701 tccattatca aatgttttcg aaacgatcaa atcgttcact gcacgtttaa tttttgctgt
    41761 tttttcaata taagctggta cgttacctgg acctacacct aaagctggtt ttcctgtaga
    41821 gtaagcagac ttgaccattc cagctccacc tgtcgctaag acgatcgcga tacctggatg
    41881 gttcattagc atagaagtcg cttcgatcga aggatgttcg atccattgga tacaattttc
    41941 aggagctccg gcagcgatag cagcatcacg taccactcgt gctgcttctg cagaagattt
    42001 ttgggcactt ggatggaaag caaaaacgat tggatttctt gttttcaacg cgatcattga
    42061 tttgaaaatc gttgtggaag tcggattcgt tgttggagtt actccgcaaa ccacaccgac
    42121 tggttcagca atttcaatca accctttttg gacatcttca ttgatcacac caactgtttt
    42181 atcatgtttg atattatgcc aaatatattc ggacgcatac atatttttga ttgctttatc
    42241 ttcgtaaaca ccgcggcctg tttcctctac agccatcttc gctaatggca tatgttgatc
    42301 caaagctgcc attgccattt catgcacgat atggtctact ttttcttgat caaagctttc
    42361 catttctttc aatgctgcat ttgctttttc tgccaaatca tcaatcattg cttgtacgtc
    42421 aattgtcttc gttttttctt tttctattac tttagccatc attatcctcc taatgggtca
    42481 tggttatttg ttaaataatt cacatgtata tcatacaata tttatttttc tatgtaaaca
    42541 cttttttgtg atttttttca cagttatttt taaatataaa attgctttat ttacaggtgt
    42601 ttgtatagaa aaatatataa agttatttat tattatttat atgacacacc cgattattca
    42661 atattgagca atatatccca tgctcttatc tctttctttt ttgaataaaa aatgaggtag
    42721 gacatctttc tgccctacct cgtctttaaa taagctttga tacttatttt tcttccttct
    42781 cttctgtctc ttccagcgtt tctgttgttt cagtttttac ttcaactgtc tcagctggtt
    42841 cttctgttgt ttcaacagta gtcgttgcat catttgttac gacagtccct ggtttgaccg
    42901 ttttgattgc tgcacgatcg tactcaagga agatcccttc gcagtctaaa acaactgtcc
    42961 gtttgtcatt gtcgatttct gaaacaactc catgtaatcc gccgatcgtt acgactgaat
    43021 cacctggttt catgctatct aacaagtttt gacgttcttg ctgttgtttc ttttgcgaac
    43081 gtgacataaa aaaccacatt gctaatagcg cgataaacat cacaagcatt ggtaatgttc
    43141 ccattttttt cacctcacta attctgtatc tacaaaaaac actttagcag aaaaatgctg
    43201 ataacactag ttttttactt aatttttaaa agattttcct ttagaagctt tttgcgtttt
    43261 ctttattgaa cccgtattct tcaaaaaagg cttctctaaa ttcaagcaaa ttatcatcca
    43321 tgattgcttg acgtacttgt ttcattagat tcaacaagaa gtataaattg tggtaagaag
    43381 tcaaacgaat cccaaatgtt tcatcacatt tgatcaaatg gcggatatag gcacgtgtat
    43441 agtttttaca tgtataacaa tcacatttct catcaattgg acggaaatca tgggcatatt
    43501 tcgcattttt cactactaga cggccttgag aagtcataca tgtgccattt cgagcgattc
    43561 gagtaggcaa gacacagtca aacatgtcta ctccacggat aacaccatcg atcaatgaat
    43621 cagcagcacc gacacccatc aagtaacgtg gtttgttttc ggggatcaac ggtgtagtga
    43681 attctaatac acgattcatt tctgatttag gttccccgac agataacccg ccgattgagt
    43741 aaccagggaa atccatcccg actagatctt tcgcgctttg acgacgaaga tcttcaaacc
    43801 ctgctccttg gatgattcca aataatcctt gacggtctgg attagcatga gctttcaatc
    43861 ctcgttctgc ccatcgagac gtacgttcta ctgatttttt cacgtagtcg taactttcat
    43921 cgaatggtgg acattcgtca aaactcatca tgatatcaga gcccaattta ttttggatgt
    43981 tgattgcttt ttctggtgat aaaaacatac gcgaaccgtt caagtgattt ttgaaatgca
    44041 cgccttcttc ttcgatattc cgcatatcac ttaatgaaaa aacttgaaag ccgcctgaat
    44101 ctgttaaaat cggttgatcc cagttcataa atttatgcag tccgccagct tcttctacta
    44161 agtcttcacc agggcgtagc cataaatgat atgtattact taaaataacg ccagcaccca
    44221 tttctttcaa ctcttctggg gacattgttt ttactgtagc taatgttcct actggcatga
    44281 acattggtgt ggggaaagtt ccgtgtggcg tgatcaattc ccctaaacgc gcgccagtat
    44341 gtttttcttt cttgattaaa cgatagcgaa tggcaggttg cgtcattcat ttccctactt
    44401 tctatataaa atatcttgac aactcccacc atcataatcg tttcaagtgc tttttgcaag
    44461 ttccctcggc ttccttctac tttatttaat attctttttt ttatcctttt tttatgaata
    44521 acaaaaaaaa gaaaaacatt atgacagaaa tattttttga tacatggtat attggtgtta
    44581 ttaaagaaaa ggagggaaaa atcatgcaat cttctgcaga attaaaacgc caagcaaaag
    44641 agagtctaaa aggacgttgg ggacaagctg ttttactaaa tctaatccct acattgattg
    44701 gtattgctac tattcttctt attatgattc ctattatctt gtttgccacc accatatatg
    44761 atggatcagc gagcgtctca gaagcgacaa cttcaggagg cggtagttca ggaggcggtg
    44821 gcggaattat ttccagcatc attagcgctt tgttcatgag cggtatttct tggacttatc
    44881 ttgatatttt acgtggacaa aaagatcaga tcgaaccatt caaagatgca tttcgtggat
    44941 tcaaaggttt gtttatcggc ggagtgatca gcttagctgt gctgatctcg atctttacaa
    45001 cattatgggg tttgctatta gttattcctg gaatcattaa aagctattct tattctcaaa
    45061 gctattttat ttactacgat atcgtccaag aaacaggaca aacacctaaa gtactggata
    45121 cgatcactgc aagtcgaaaa ttgatggatg gttataaagg acaacttttc tggttagatc
    45181 tttcatttat cggctggcat atcttagcat tagcaactgc tggtattggt tatctatggc
    45241 tcagcccata catttctgca acaaaagcag cattttatga acaattgcca aaagatattt
    45301 aaaagagagt gtgacttgtg accgaggggg tggcaggaga acaccgttta tcgagaggca
    45361 gtaaaagaaa cattcagccc attagcaaaa aggaggtgtg acaacattca tgtcacacct
    45421 cctttttgta tagttccagt aaaaagaaaa tcaacttaga aacagttaat cattcctctt
    45481 cttctgcttc cggtaatcga tggaacttga tcagttcatt caccgcgatt ggtacgatag
    45541 ataaaatccc taccaagaac cagtgattca aactgatgtg tactaggccg aatagttctt
    45601 gcgtaaatgg cagcaaagca acagccgttg taatagctaa tgccagtaac gccatttcta
    45661 ccaaagcttt attggtcgct aaattgactt tgaagatcga ttggctgctg cgtacattga
    45721 acacatgcag aatcgatgaa taagctaaga tcaagaatgc aacagtttga ccgacatgct
    45781 gacttgcgtc tacccatggg ctgatagtat cgacataact acctaaataa taaccaaaca
    45841 aggttacgat ggtgaagacc cctgcattta tggcaatttt ttgcaataaa cctcgagcaa
    45901 agatcccttc atttttcgga atgggtggct gatccatgat gccgtgttcc gctggctctc
    45961 ttcctaaagc aaatcctgga agtccatcag caactacatt gacaaacagt agttgcacag
    46021 ctgtaaatgg tgctccccat cctaacagca tcgcaatcaa aacaataaag atctccgaaa
    46081 tattacagct tagcaaaaag ttgatagctt tacgaatatt ctgataaacc gaacgtcctt
    46141 gactgacagc gtctacgatc gtcgcaaagt tgtcatccgt caaaatcata tctgcggcac
    46201 tttgcgccac atctgttcct gtgatcccca tggcacaccc aacgttactt gctttcaacg
    46261 ctggtgcatc attcacacca tccccagtca tcgctacgac tgcacccgta cgttgccaag
    46321 atttgacgat ccggatcttg tcttctggcg ttacccgagc atagacagag agagctttga
    46381 cacgcgcatc taattcttcg tctgataatt gatgcagttc tgatcctgaa agtgcttctg
    46441 acggatcatt caagatacct aattctttcg ctatggcact ggcagtcacc acatgatctc
    46501 cagtgatcat gactgttttg atgccagcct ttttcgctcg cttgattgct cctttacttt
    46561 ctggacgtgg tggatcgatc attccgatca gaccaatcaa acgtaagtct ttttccagtg
    46621 cttcagaaga aatatcttgc ggttcttcgt cataagtagc ataaccaaca gcaatcactc
    46681 tcagtgcccg tttaccaaag cgatcattaa cgatcgccgc ttgttctaca tcgcctgaac
    46741 taaagcgcgg agcaagaaca tcgaatgctc ctttggtgat tgagatgtat ttttcgccca
    46801 tttggtgaac tgttgtcatc atttttcgtt cagaatcaaa aggaagctcg tttactcgtg
    46861 gatatttttc ttctaattct gcctttgtat gataattctc ttcaacagcc cttacgatgg
    46921 ctacttctgt tggattacct ttgataacaa ggtcgtcatc ttcttgctcg accgtcacat
    46981 ctgtacatag tgcagccatt ttcaatattt ccatcgcgct gttcgtcatt gaatcttcga
    47041 tattcgttac ttcatcttct ttgctccata cccggcggac gcgcatttca ttttgtgtca
    47101 gcgttcctgt tttgtctgag cagataacat tagcggttcc tagcgtttca actgctggca
    47161 actgtcggat gatcgcatgt ttcctcgcca tcttctgcac accgtatgca agtgtcaacg
    47221 taacaataac agtcaaggtt tccggtacag ctgcaacagc caaggaaatc gaagtcatga
    47281 acatctcaag gagtggttct ccttgcagtt caccaatcac aaatactaaa gccgcagccg
    47341 ctaaagcgat catactgatt cgtttgccta gctgattcaa tcggacctgt aaaggtgttt
    47401 tttgcatagt attttcgttc aaaagatccg cgatcttacc catttctgta gccatgccaa
    47461 tggcagtgac gatcgctttc ccacgacctg cagcaaccgt acatccttta aataccatat
    47521 taagttggtc acctaatgac tcatcttctt cagcaataaa tgctgcatct ttttcaactg
    47581 cttcactttc tccagtcaac gccgattctt ctacacgtaa ttgtgatgct tcgatcaaac
    47641 gggcatcggc agaaatagca tcaccggact ctaaaacaag aatatcaccc actaccagtt
    47701 gctctgactc aacagtggtc actttgccgt ctcgtatgac agttgccgtt tgtttattca
    47761 tatcttgcaa ggattccagt gctttttctg cgtttccttc ttggacaatc gccaataccg
    47821 agttgatcac aacgatagcg atgatcagca gtccttcaaa taaatcccca tgttctgtag
    47881 caaatgcggt ataaaaggaa atcaccgctg ctacaagaag gatgatcgtt gtaaaatcgg
    47941 acaagcttcg aaagaatttt ttgatcatcg attctttcgg cgcctcatcg aatttattca
    48001 atccctgctt ttttcgccgt tcatccactt cttgtgaaga caacccagta tctggatctg
    48061 cttctgttac cttctttact tcttctattg tctgcttgta ttcttccatc ctattcctcc
    48121 tttaaaatct tcgtacaaaa aaaggtactt attttactat aacatccttt ttttatttac
    48181 ttcaaataaa gggcttatcg attatttgtt aagaaagcgt aaaatttaaa gtgcttatat
    48241 ttgcaaacgc taccaaagga tgctattata tagatgtaag gaaggaggat accatcaaat
    48301 agacagaaga atttctcgat agaacagtgt aagcaaacaa agttgttaga agtacaggtt
    48361 tcacccagac atgcgtgtag agtacaaacc tataaatagt gaatgcgtat ggatgtttgg
    48421 atcacgaagt atccgaaaca agaagtaatg cgatacgtaa caattgaata acgtaaacgt
    48481 ctgaaaattg aataggaaca agagatgttt caaatgttga agatgtaacg aaaacaaaat
    48541 ttttgtttaa catgaagaaa ttcaacaccg tgctttgcat gtatgatgga aagttacaat
    48601 catttctgtt tatttgaatc cttccgaggt acaagaaagc cgagcttatc gagagctcgg
    48661 ctttttcttt gtcataaaat ctttgtaaag cttttttgtt attcaaaact agcggctttt
    48721 cataacctta tttcacgaac atcgcatctc caaaactaaa gaaacgatag cgctcttcaa
    48781 tcgcatgctg gtaagcagat aaagtcaatt ctcttcctgc aaaggcacta actaacatga
    48841 ctaaagtcga ttttggcaaa tggaaattag ttgagaaagc ttctaccact ttgaattcat
    48901 agccaggcgt aatgaaaata tcagtccatc cgctgtctgc tttgatttct ccattaaatt
    48961 tcgttccaat cgtttctaat gttcgaattg aagttgttcc gacagccacg attttcccgc
    49021 catttttacg tacttggttc aatcgctcag ccgcttcttc cgtcaaacgg tagaattcac
    49081 tatgcatatg gtgttcttca attttatcta cgctgacagg tcggaatgta cctaacccta
    49141 catgtagtgt cagatagact aattcaacac cctttgcttc gatctcatca agtaattctt
    49201 tcgtaaaatg caatccagct gttggcgctg cagcagaacc attttctttc gcatagacag
    49261 tttgatagcg atctgggtct tccagacgtt ctttgatata tggaggcaat ggcatttctc
    49321 ccaatgattc aagaatctct agaaaaattc cttcatactc aaagtcaatg atccgtccgc
    49381 cgtgttccaa ttcttctttc actactgctt gcaatctgcc atcaccaaaa gagattcttg
    49441 tcccaacttt ggcacgtttc gcaggtttga tcaatgtctc ccacgtatct ccttgtgtat
    49501 tcgttagaag aaggacttct aaatgcgcac cagtatctgg tttttctcca tataaacgag
    49561 caggcagaac tcgtgtatta ttcataacta gcgcatcacc aggctgtaac tcttcaatga
    49621 tttcatggaa atgtttatct tccatctctc cagttttccg atccaaaaca agtaaacgag
    49681 aatgatcgcg gtcttttaat ggtgtttgtg cgattaattc ttccggcaag tcaaaatcaa
    49741 aatcttctgt tgttaacata tcgtcactca ctttctatca tgtgcttcat cattctatca
    49801 tgtttttcgt tctgttggca aaatcagcac tttttcactt ctattttttg ttttcctaaa
    49861 taaaaaaact accctatttg tattttttca ttgttttagg catactagta atagatagtt
    49921 cttcattgaa aatagaaaaa gaggtggcac catgattgaa tttcaaaatg tgtcaaaaat
    49981 ttataaaggt ggaaaagtcg ctgtagagga cgtcaatctt tcatttgaaa agggtgagtt
    50041 catttgtttt atcggtacga gcggaagcgg aaaaacgacg acgatgcgga tgatcaaccg
    50101 aatgactgat ccaacacaag ggaaaatttt gattgatgga aaatccatcc aagaaattga
    50161 tccagtggaa ttgcgacgtc agatcggcta tgttatccaa agtattggat tgatgcctca
    50221 catgacgatc cgtgaaaata tcactcttgt ccaaaaattg ttgaaagtca gtcaagaaga
    50281 acggaataaa acagctgaaa aaatgattga tcttgtggaa ttgccccgtg agatgttaga
    50341 tcgctaccca catgaattat ctggtggtca gcagcagcgt attggagtcg ttcgtgccct
    50401 tgcagcgaat caagatatca tcttgatgga cgagccattc ggtgcgcttg atccaatcac
    50461 tcgtgattcc ttgcaagacc ttgtcaaaga tttacaagag cgtttgggaa aaacgatcgt
    50521 atttgtaacc catgacatgg atgaagcgat taaactagca agccgtatcg ccatcatgag
    50581 tgaaggccgt gtgatccaat ttgatacacc agaaaatatt ttacgtcatc ctgcaaacga
    50641 tttcgtagaa gagttgattg gagaagatcg cctactacaa gccaagccaa atgcgacaag
    50701 agtcggcgaa gttatgctaa atacagcaat cacgattaca ccggaaaaat cattacaaga
    50761 agcaatcaaa ctgatgaggg aaaaacgtgt agatacgttg ttagttaccg ataattcgaa
    50821 tgtattaaaa ggatttatcg atgtagaaac gttgaataaa aaacgaggaa aagtatccag
    50881 tgtcggcgac attttgaata aacatgtttt ttacgtaaaa gaatccgcct atcttcgtga
    50941 taccttgcaa cgcattttaa aacgcgggct gaaatacgtg ccggtcgttg atgaacagaa
    51001 caaagtcgta ggtatcctga ctcgtgcatc attagtggat atcgtctacg atgtgatttg
    51061 gggagaagat cccgcaacta ctgatgttgc agagtcagct actcctgaag aatctaagga
    51121 ggtctgacct atgcagcagt tttttcatca gcacggttca gaaattctct caaaaggttt
    51181 tgaacatctt tatatttcag gacttgcttt gatcattggt atcatcattg ctgtaccgct
    51241 tggtgtctta ctgacacgtt ttccaaaagc tgccacgatt gtgattggct taaccagtgc
    51301 cttgcagaca atcccttctc ttgctttatt ggcattgatg atcccgctat ttggcgtagg
    51361 taaattacct gcgattatcg cactctttat ttattcatta ttgccgattt tacgtaatac
    51421 gtacattggg atgaaaaatg tcgattggaa ttatcgggat gtggcaaaag gcatggggat
    51481 gactgagttc caatccattt tttccgttga attgcccatt gctatgccaa cgatcatggc
    51541 tggtattcgt ttagctgccg tttacgtgat tgcatgggct acacttgcct cttatatcgg
    51601 cgctggtggt ttaggcgatt tgatttttag tggactgaat aattaccaac cagatctcat
    51661 tttggcaggt acgatccctg taacaatttt agcactattg gctgattggc ttctaggtct
    51721 cttggaacac cggctgacac cgatcgcact tagagaggag aatgaagaat gaaacgtata
    51781 ctaaaaatga ccatggttct tttctctctt cttatacttg cgagttgttc cttccctggt
    51841 cttgccagca atacagatga agacaccatt tcgatcacag gtggaatcac ttcagaagca
    51901 cagatcttag caagtctagt tgccggaatg gttgaacatt atacagataa aaataccgca
    51961 atcatcaaca atctggctac tacaactatc aaccatcaag cgatgatgaa cggagatgct
    52021 tcaatttcag cggctcgcta cacaggaaca gatttaacga ctacattgaa ccttcctcct
    52081 gaaaaagatc cgaaaaaagc gtttgctacc gtgaaagatg aatttgagaa aagatacggt
    52141 caaacgtggt tcccgtccta tagttttgaa aatacgtatg tctttcttgt tcgaaaagac
    52201 accgcacaaa aataccatct atctaaagtc agcgatctga aaaatgtagc ggatgaatta
    52261 gtagctggtg tagatacttc ttggatcaat cgtaaaggag acggttatga cggcttccaa
    52321 gaaacttatg gcttctcctt caattcgata ttacctatgc agattggact tgtttatgac
    52381 gcagtcgaag caggaaaaat ggatattgtt cttggctact ctacggatgg acggatcgcc
    52441 agttatgatc tagtcatgtt ggaagatgat cgtcaattct tcccaccata tgatgctgct
    52501 ccagttgtag acaacaagat attagctgat acgcctcatt taaaagaagc cttaaataag
    52561 ttaggtcata ccatcagtac ggaaaaaatg caggaattga actacgaagc agataataat
    52621 ctagtggaac catcagtagt agcacaacgt ttcttacaag aaaaccacta ttttgaaggg
    52681 aagtgaagca attggataaa atgaatgtct ttcaacaatt tttctattat ttccaggaaa
    52741 atggctccta tatctttgca caatttatcc gtcacttcct gatttctatc tatggtgtcc
    52801 tctttgcagc agttgtcggg attccggttg ggatcatgat ttctaggaga cgtaaattag
    52861 caaactgggt gattcgtttg gcgaatatca tccagacgat cccttctcta gccatgatct
    52921 ccattttaat cattggatta ggcctgggag tcaatgtcgt gattgttact gtatttttgt
    52981 attccctctt accgatcatc aagaatacgt ataccgggat gatccaagta gacaaaaaca
    53041 tccttgatgt cggcaaaggc atggggatga ctgctagaca acgactattc atggtagagt
    53101 taccactctc tgtttctgtt atcatggcag gcataagaaa cgcgttagtt gttgccatcg
    53161 ggataaccgc gatcggtgca ttcgtcggtg ctggtggtct tggagatatc attatccgag
    53221 gaaccaatgc aacagagggc acatcgatta ttttagcagg tgcattgcca actgcattaa
    53281 tggcgatcat cacggactgg cttttaggta ttttggaaag acggctagat ccagccagcc
    53341 gtacatcacg ctgatgttat tgtaaaaaac aaaagcttct gcgaccattt gttggtcgca
    53401 aaggcttttt tagttctgtc atttttaagg caataatcca ctctgattct tccctcctta
    53461 tgggcaaaga gttgcttttc ttagctattt atccattccg tatactccaa cttcatactg
    53521 ccaacgggtt catatctgca tccaccgact aagttttttt cttatccgct aaggcatttt
    53581 gccaatccat tttcccatca ctcgtcatgg aattcatacc acatgatctc taaatactcg
    53641 tctgcttgtt ctttgaattg ggcatcaatt cttacatcct ttggcgtggc tttcatttaa
    53701 gccttttcca tcagtcctcg attgttcgat gccttcagct gcatcatcaa aactggtgac
    53761 tgccgtatcg gtaacttcga tcatctttta tacaatcggg aacttgccat cctcatcctt
    53821 ggctaaaaac atatctagcc attccagctt ctcgccatgg gaggtttgcg gttcctaaaa
    53881 ccggtacacg attcttatgg actgcatccg tcgcaactag acttggcgat acgatgatcc
    53941 ttcaccagaa gagcaccccc gtaaaccaat tgatcgatat attgccaata agaaaagaca
    54001 ttggcgtaaa agatatcgat ccctcgtgat gcattgccgt tgatactgct attcatggcc
    54061 gaaagcgcca cgactttaac ttcttccgtt tgagtgacat tcatgttcgg caatgtcgct
    54121 ttggataccc gctctgctaa aggaacgaca ctggtattgt atttcgtatc tgtatctttt
    54181 ccaaaagacc atgccaacga atcctctggg aaccaataag acgactccgg ttgattgtcc
    54241 attgcttttt tcaacatact tttggctgtt tctcgataaa cgacatttcc aattgtcttc
    54301 gcctcacttt ggcgataatc gatggtcgtt gccactgcca acactaacaa cgatgctcca
    54361 attttactga ttttccttgt cacacttctt cctccttgtt ttacataaac ccgtcaacat
    54421 tccattccta aactcaaaca atgacccttc aaaggtggag atataggaac aaattaaaga
    54481 aatcatgcaa taaatccaag aaggttggtt ttagaacaaa aaaagagtct cctttttggg
    54541 gagactcttt gttaactatc taaaaaggtt ggctcttctc acttcactca taatgtgtcc
    54601 aggcagaata aatttctaca actttatttt cctcatcaac tttgtaaacc actcgatgct
    54661 gtctattcag cctgcgtgag tatctgcctt catgtgtagg tctcagcttt tcaaaagact
    54721 gcgtgggcat atatggatct tccttcaatg tctgaatcac ttcttcaaat tgtttcttta
    54781 aattcgtttg cttgattttt cttaaatcca ctttcgcaga gtttttgatt gcgactgtat
    54841 agttactcat caaagagctt cccaatcaat atcatcgata ttcgtaaagc tactgtcgtc
    54901 tttttcgcgg tctcgtactt tatctaaagt acctgtttgc tcaagaaaaa gggtttcttg
    54961 aatcgctctc cagtcttcca gcccaatcaa tacagcattg tttccactac gatcactaat
    55021 aatctcgatt tcagtatgat tttcatttac ctctttcaat aactgataaa aatttttacg
    55081 agcagtgcta ggattcatcg ttgtattagc cattgtctct cctccttttt ctgatataat
    55141 tatagcgtac ttgattaagt acgtcaaaaa aatacaataa agcacttaaa ttcagcaaac
    55201 ttttcctctt ttttacatag agaaaaagac ccctttttag ggaggatctt tgtccacgct
    55261 cacttcttac tcctttacga ctagcggtag ccaaacgtaa agtaattggt aacaacgtat
    55321 catctttagc aaaggtcgaa tccaaagcct gtgagtctat gcaacaacac caatacacga
    55381 aggttcctcg ttgcagtgtg acttgattga tatcttgaat aacctgagga tacgcacgaa
    55441 agatttgtaa cggttattca aaactgattt tggccgtcaa gtcttctact gcctcaaaaa
    55501 tgattgcctc tttcgtctcc tgtcattcat gttcactatc gatttgatac ttgcttagac
    55561 cgttgggttt gtgaatcacc aattaaaaat ggcactgagt tatggtaaca aaaaatggtc
    55621 acttgacgag gctgagattc ctacttatga agacacatgg cacttaagag tcgaggtaaa
    55681 ggaagaagct gaaaatatag gaggctgtac attatttggc aaaggattcg gaaattatga
    55741 tcaagacatc aaaatcaaaa tgttttacag ctaaatagga agaataataa catttcatac
    55801 gctgttccca tctttaatgg cttatagagg gcacctttag ctgagaataa gacaaaacag
    55861 accctctagc ttcaattaag agctagaggg tctgtttttg attttaaaac ttggtttatt
    55921 tcttcaaatg gtagctatag gtgctgacaa cgatattttc acgccaagac aatcgcaatc
    55981 ttaaccgcaa acttgtttgg ttatggagaa tattctgcca gcgtctgttt ggtacaaatt
    56041 gaggaatcaa cacagtagtt gtatagtttt gtttcgctgc atttttactt acgatatcta
    56101 cataacggat aattggattt tcaatcgagc gataagaaga gtggacgatt gaaaaacgga
    56161 catctgggaa atgcttttta aattctgctt cgatttcttt ttctttttcg acatcttcgt
    56221 ctagcgaaac atgcatcgca acgacataat caccgatcga acgtgcgtaa ttcaacgcac
    56281 cgatatttac ccgtgtcaca ttcccgacta atacaagaac ggtattcccg tcataatcat
    56341 gtagttttgc atcattttct aaacgaagct gttctgctac ttttttataa tgatcatgga
    56401 tcttataaaa aatgaacata acgattggca taatgatgaa gaaaggccaa atgtccccta
    56461 accgatagac aaacaaaatc gcaatgattg catatgagat gaacgcaccc gtaatattgg
    56521 caatcgattt gcttaaccat ctttttcctt cttttttcca tttgacgacc atccctgttt
    56581 gagataaagc aaatggaatg aacacgccga tagagtataa cggaatcaag cgttctgttg
    56641 agccatggaa aataaacagc aatacgatcg aacctagcgc tagtgtgata atcccattgg
    56701 aatagcctag tcgatcccca cgatcttgat acatgtgagg catgaattta tcttttgcca
    56761 gattgtatgc aagaactgga aaagcagaaa aaccggtgtt agcagcaact gctaaaatca
    56821 gcgctgtagc aaattgaagg acgtaataca aaataccatg tccaaagaca gctttaccaa
    56881 tttgagacaa aacagtgact tctttttcag gaacgatccc ataccaatag ttgataaatg
    56941 tgatccccac gaagaagaaa cctaagatca atgccatcat cgtcaatgta gcagcggcat
    57001 tttttgctct tggcttctta aagaatggta cagcattact aatcgcctcc accccagtta
    57061 aagaggaaga accagaagaa aatgctcgta aaatcaaagc gatagaaaca cccggcacag
    57121 ccgctcctgg aagtgcagta gcttgcaatg gcacagcacc tgtcacgata ttatataaac
    57181 caacaacgat cagtaacgag atcacaagga taaatgtgta caccggaaat aataggaacg
    57241 atgcagattc cctcagccca cgaagattca gcatcatcag tagcaaaacg attgtcacag
    57301 aaatagcgac ttgatgaccg tagagtgctg gcaccgctga tgtgatcgct tcagcacctg
    57361 ctgagacaga tactgctact gtcaacatgt agtcgatcaa taaagagcca ccggaaatca
    57421 agccagcatt ctttccaaga ttctcactgc tgacgacata tgctcccccg ccatgaggat
    57481 aagcatggat gatttgacga tatgatagcg ttaatgaaat caataaaata ataacaaaag
    57541 cggcaatggg tagcgaatac cagatggctg cagcagacaa agcgactaaa acgacaacga
    57601 tttgttccgt accatatgca atagatgata acgcatcaga cgacaataat gccaaagcag
    57661 caaatcgggt taatttgtgc tcatcatttt cagcagattt taaaggctta cctactaaca
    57721 acctttttaa gtaatccaat ttctaaactc ctttacacac aattttactt caagttttat
    57781 agtcgaaaat ttatagtaaa caagatgtta tagtacgctc actgacctta aaagtcaata
    57841 aactttaaga aaataattgg aaaaaaacag aaaaatatca agcgcttttt caaacgcttt
    57901 aatacagcaa aaatctaaca tttttttatg ggctttttct ttgaattcta taataaaagg
    57961 atagaacttg acttagaaaa tcaagttcta tcctttttga tatcttaact tttggaagag
    58021 agatgtaagg ctgctttcta cccatcattc ttactactcg aagcatagcg cagttgtcac
    58081 aacctcttga taaacggtgt ttaaaagctt gcatctgcgg taataagccc aaccaaatta
    58141 aaaacataag aagctgtttt tatttggtcg ttcttattac ttgatgcaga gcagcttttt
    58201 tacaacctct tggtacacgg tgttcaatca gctgaccctc ggtattagct caaaaaaacg
    58261 gcaaaatatg aggaactatt tttccatttt tttctctaat actcaggtca aaacactgat
    58321 ttcacaacct ctttttttaa tgaaaaatat ggctctcatg cgccgcttct ttgaatttcg
    58381 tcattttttc ttcgatgaac ggatagattg ccgttcctac gattccaaag acaacaaaca
    58441 aaccgatcat gatccagatt gctttcgtag catttggcca ataaattcct cctgcagatt
    58501 cccgtaacaa gtttaccgca tgagtaaatg gcaagaacgg attgatcatt tggaagaatt
    58561 tccctgagac ttggatcgga tagttcccgc ctccgccaga gatcgacagt actaagatga
    58621 taatagcgat ccctttaccg acattatcga ataatgcagc caagacatag acgatcatca
    58681 tgaacgctaa ggcgatcaag acagcaaatg acacgctgta gaccggattt tggacatcta
    58741 ctcctagtaa gaaaatattc cctaatgtaa cgatcaagct ttgcgcaatc gccattgtca
    58801 aaaatgtcag catacgagca acgaattgtt ctcgtttcgt aaaattgttt cggtctttct
    58861 ttcctaaata gtattctgtc gtagcaacac ttgaaagaag aacagcgccg acccacagac
    58921 atagtgcagt ataaaacggg gtgctagctg aaccgttatt tgcgattgga taaagcgcat
    58981 tggtttgtag ctcaacaggt tgtgtaaaga agtcactttc ttttgttgcg tctagtttca
    59041 ataatttgat gacttcgcct agatcgactt cttgttcgcc ttttcggatc gcgtctgctg
    59101 ctttttggat accagctttg atatttggcc agtcattgtt gatcaagtcc gcagcagcgt
    59161 tcacagctgt ttcgacttct ggcatttttt catttactgt tgtcaatgta ccggtgattt
    59221 cattttttag tgctggccaa tcattttgga taaaatcagc ggccaatcct aatttttgct
    59281 gaatgatcgg taattcattg ttgtataggt ctgccccttc attgatgcca ttgacgatgg
    59341 tatccatatt tccattcagc attgtattgg catcatggat ttcttgtcca attgcaggca
    59401 tttctttttg atatttttct aaaattgcca ctgcattcgt tacagttgct ttcgttgagc
    59461 tgagaagcga atcaaagtcg atctggtccg ctttgctcag tgcgccttgt gcagtcccaa
    59521 tcgtatcgat gacttggtct agtagagaag tgacagtgga actgatttga cctgtattga
    59581 taccagcaat gatgccattg atattattaa caacggcatc aatttgatct agcaattcat
    59641 caatagcctt cgtgtcttca ttttgaacag ctgtgttcaa agcagatagg cggttttgca
    59701 gattgcttag caagggtttt aattgattta gctgatcaat aattggctgt aatttcgtat
    59761 ttccagcact tgtttgcaat ttagtcagga actcgaccag tttatcgatt gcattttgtt
    59821 gttgagatat tccgtcaata aagccgttca atacattgct gatgtttttc ttttcatcat
    59881 cagtcagctt accatcttca atagctgttc ttacagtatc tattaacgaa cctgtcgttg
    59941 ttgccacttg tccaattgac ttcaatgtaa catctacact gtttgtgatg cttggtatcg
    60001 catctttcag ctgagaggca cctgattttg tttggtttgc tagatcactt gcctgatttt
    60061 ctaaattttt cacatctggc aagatatctt gtacttgttg gatgatcgtc aagccttgtt
    60121 ttgcttcatc gattccttgg ttcattgtct cttggatcga agcaaaatcg ccgtcgatct
    60181 ctgctagttg cttaccggca ttttggatct ctgggatttt ttcttgcaaa tcaaggatga
    60241 tttttgcttg atctttcaac tcaggcattt tgtcattcaa tgcaacgact ttttcaccca
    60301 tctcatctac tttagggatg taatccacga attcatttgc tttattcagt ttttccttga
    60361 tttcaggtag ttgactttgt aattcgagga cttgttttgt gtagccgtcg atcgtgtcca
    60421 aattttcatc tgttgataaa atcatatctt taactttatt gatacttact aggttcgtat
    60481 cgatgtcgta acctatctca ttgaatactt tcaataaagt cgaactggct gttttgataa
    60541 attcatttgt gatttgcgat tggatcgaac ttgctccttt atcggtgatt ttcggtgcaa
    60601 tcgcattgat tttttcattt accgtatatt cgatttttgg tttcttgata tcaccactag
    60661 taaaactcag cagatcttct gagaaatcct ttggcaagta aatacctgcg taatactttc
    60721 cggaacggac tccgtcttct aattgttctt ttgaatcaac gaattgccat cctaattgtt
    60781 tatttttatg aagcgattcg atgacttgct ccccaatggc cacttcttta ccttgaaact
    60841 ctgctggctt gtctgcactg taaacagcaa ttggcagctc tccagtattt ccatatggat
    60901 cccataatgc tttgatgtta aaccacgcat atagcgaagg gatgatcatg atcgcgatga
    60961 tcagaagtgt tgcaatcggg tttttgaaaa tccgtttcca gtcaagcaaa tataatcgaa
    61021 gcgtattttt gattgactgc atagttctcc cccttcttct tttttcagct gaattacttt
    61081 accatgtatt tcatactttt ttcaatcggc ttttttcaaa aaagtcgaat ttttggacat
    61141 atcacggcaa ttgtctcatt gtaatctctt acatattgag aaataattaa ggattacagc
    61201 ctttacttta tcatgaaata aaagggaaag ataattttat gccaaagttt ttatctatta
    61261 tacgtatacg caaaaaagct aaaacatttt ttgtctttgc ccctacaaaa atgtttcagc
    61321 ttttttcgtt ttttattcct gtatttctta tttttcgaat gacaggatga ttttcccagc
    61381 aggaggatgt ccttcaacta gctgatgtgc ttggatgaca tgcttaagtg aagcagacag
    61441 attcattgaa ataaaaacat gaaaggctcc tttttggtag gctttgatta tgccagcaaa
    61501 ggcttctgca tctagatatt cctttcttgg aacaaacgat tcataaaagc cttccttttt
    61561 ttgccgcaaa tctagatctg ggaggtcatt taatgcaaca tacctgccgc ctggtttcat
    61621 gatctggatg ccggtttctc ctttgatact tcctttcgtc gcatcgatta caaggtctgc
    61681 ctgatcagca aattgcagac ctggatttgt tttatcataa gcagcaaatg ctgaagctcc
    61741 taattttttt accttttcct catttttact ggatgcactg gttaagattc ggattccctt
    61801 ttcatggaga agctggatca gacttgaccc gaccgcacct gatgctccta gtatcattac
    61861 agtatctgtc ggctggattt ccgtcaaatg gttgattaga ttataagccg taattcctgg
    61921 cgtgaccatt ccggctgctt cttcccaact cattttatct ggaatttttg ctacttttgc
    61981 tgatggcaac acgacttctt ctccgtaagt cccgccgact gcatggacag ctactcgatc
    62041 acctacatga acagttgtga catctgaacc aatctctgtc acaataccag cgccatcatt
    62101 acctggtaca taagggaatt tcaatgttcg tatctctttc atttctccta aacgcaaggc
    62161 aacatcataa ggattcacac tgaatgcttt tatttctaca cgaacatgtc cagaaccgac
    62221 ttctctggga tgagcatcga tttcttcaaa aacatcttgt gcttctccgt aaccgttaat
    62281 tgcaaatctt cgcatggtca ccatctccct ttttctttaa gtttacgttt atgcctttat
    62341 tttgacaaaa aaaatgtctt ttcgttttgg cgcatgattc aaaacaaaat agttgtcttt
    62401 tttcgcgtaa cgtgttaaat tatttatcta aaagcgtaaa gattacgatt tacgctaata
    62461 aaaaataatt ggaggaattt gttgatggct aaaaaatcaa agattgccaa agcaaaaaaa
    62521 cagcaagaaa cgattgaacg ctatgctgct ttacgccagg aattaaaagc gcaaaaagat
    62581 tacgaaggct tgcgtaaact tcctttagat gctcgtccag aacgattgaa aaatcgtgat
    62641 ttaatcgatg gacgccctcg cggatacatg cgtaaattcg ggatgtcccg tataaaattc
    62701 cgtgaattag cacataaagg tttgattcca ggagtaaaaa aagccagctg gtaatccaag
    62761 tctggctgta atgtaaagga ggagggcgca tggaccactc cttggatcat caaaaaagat
    62821 acgttcgctt cttctagcag aaatgctggt actagaagca gacgtatctt tttttacgca
    62881 cagctggtcc ttttttatat gtaaaggctg catggttact tcgctatatt tatttagtaa
    62941 caggagtcag tgcttcgata cccacactaa ttttcaatgc tcggtcaact tctgccataa
    63001 tgggtcgatc caaatggcag accttttctt tcaatcttga tttatcgatc gttctgatct
    63061 gctccaacag gataacggag tctctttcta ttcctgttcc agtagctttg atcccaatgt
    63121 gagtcggaag cttaggttta gccatttttg ccgttatggc cgcaacaatg atcgtcgggc
    63181 taaaatggtt acctagatta ttttgaataa ccaaaactgg gcgtgttccg ccttgctccg
    63241 atcccacgac tggagaaaga tcagcaaaat aaatatctcc tctttttacc ataggatcct
    63301 ccttattctt gatattctct tggtatccgc tgtcctaatc cgcaagccac ttcatagtgg
    63361 atcgtaccta attgatctgc tatatcctgc atagtgattt ctttgtctgc atttttgccg
    63421 ataagcgtca cttttgttcc gacaggaaat tcttgaggca atcggatcat cagttgatcc
    63481 atacatacac gcccaatcgt ttcacagtag ttcccttcta ccaatagaga aaaaccctgc
    63541 atctttcgtg gccagccatc tgcataaccg atcggtatcg ttccgatcca ctctgcttca
    63601 ggagtgatat atgtttctcc atagccgatt ccttcacctg ctgggagttt tttgacttga
    63661 atcaattcag aaaccagctc aagtgctggc tgcaatggat aaacttccgg tagtgcgtgc
    63721 ccagagggat taagtccgta cattgctact ccataacgaa tcatattgcc gattgtttca
    63781 tcatgccata aagccgttgc actattgctg acatgtacat atcgaggaag ttcgggaagt
    63841 tttttcagca cttctataaa gcgttctttt tgcagattcc aatatgtatc atctgcctga
    63901 tctgctgtag aaaaatgggt aaataaacct tcccattcta atacacgact ttctttgatg
    63961 aatgcagctg cctcttttac ttcttcaggt gtacaaaatc cgatacgacc catcccagtg
    64021 tctgctttta gatgaatcga aagaggcgtc tctagcttac ttttctctaa aacagcagct
    64081 gctgcttgca accattcccg tgtacctgca gttactgata aatcatgagc aacagctaca
    64141 gtcagtgcgt cgtaaggaac catattcaag ataaggatgg gctgagtaaa tccagcttct
    64201 ctcaactcga ctccttcatc taaatttgaa acacaaaagc ccgaagctcc acctgcaact
    64261 gctgcctcag ctgtttcaat agctccatga ccgtatccgt tcgcttttac tactgcaaac
    64321 aattcttttc cttgcggaag tcttgcaact tcatttgcta cattttcagt tatagctttt
    64381 ttatgtatca ctgctttcgt tgggcggtgc caagcgacaa ccatcgtttt tccttctttc
    64441 tagtcttcca aaataatttg tgcaaaagct gtttcatttg tatgagtaat actgacccat
    64501 acattgcctt catgaggtga acgcgtcaca acaggctgac cattttcatt ttttaaaatc
    64561 tcgacatctt gaaaggtaac ttttccgatc ccagttcccc aagctttaga gaaagcctct
    64621 ttgcaagcgt aacgcccgcc taaaaattct acttggcgat gaaaaggcaa ggactggaat
    64681 agtttcattt catcagaggt caagattcgt gcaatgaatt ttggtttttc ttcgatcagc
    64741 cgagtgatcc taggaagttc gactgcatcg atcccaattc cttttatcat atgcttttct
    64801 cttttcaata aatttagaac actctcattc taccaaatta taaccatttt gccacaaata
    64861 agtccacaaa taacaaaaat gaaagtttct cttaaaaaag agaaactttc attttatgtt
    64921 taatcgttat ttgaacggat tacaaatccg cgttttttat cattgtgacg tttaccgcca
    64981 tctttttggc tgttattatt tttgctataa ccgccttttg atttgtttcc acgataatta
    65041 ccgccgtcac gacgattacg gttgtttccg ccaccacgtt tgccattttt attgtatcct
    65101 tttttctgca ttggcaatgg gcgttctggt gtgatcttca ctggcactgc atcagctgga
    65161 tcttttgctg tcgtttttag caaaagtgca actaaatctt gtgcagaata ttcttctaat
    65221 aatttatctg ctgtttgcag gtatttatct agaccatttt ctgcaagttt tgtttcgatt
    65281 tgttcaactg cagcacctaa ttgacctttg aatgcttctt tttcggttgg tggacgtaaa
    65341 gtcgtcatcc gttttttcgt caagttttca atcacatgca agtagtccat ttcatttggt
    65401 gtaacgaaag tcacagacat accgcctttt ccggcacggc ctgtacgtcc gatacggtga
    65461 acgtagcttt ctggatcttg agggatatca tagttgtaca catgagtgac acctgaaata
    65521 tctaatccac gtgcagcaac gtctgtcgct acaaggatat ctaaatgacc gctcttaaat
    65581 gaacgcaata cgctcattcg tttttgttga gacaaatcgc catggattcc ttctgcacgg
    65641 taaccgcgtg cttctaatcc gcgtgccaat tcgtctacac ggcgttttgt acgtccgaag
    65701 acgattgtta attcaggtgt ttgaacatca aacaagcgag tcatgatatc gaatttttcg
    65761 tattcttttg cgcggacata gtattgatcg atcaagtcag ctgtcatttc tttcgctttg
    65821 atcttcacat gatgtggatt tttcatgaat ttaacgccaa tattcttgat agctggcggc
    65881 atcgttgctg agaaaagtaa tgtttgtctt tgatcaggaa cttgtgaaat gattttttcg
    65941 atatcttcca agaagcccat attcaacatt tcatctgctt catccaaaac taatgtttga
    66001 acggttccaa gtttcaatgt gtggcggtta atgtggtcaa gcatacgtcc tggtgtaccc
    66061 acaacgatat gtggacgatc tttcaagcca cggatctgac ggccaatatc tgctccgccg
    66121 taaacggctt gtacacgtac ttttttgtcg cgccctaaac gatataattc ttcttgtgtt
    66181 tggatagcta attcacgtgt tggtgcgata actaaacctt gtaattcgtg acgatctgga
    66241 tcgatttttt ctaacattgg taatccaaat gcagctgttt tccctgtacc tgtctgtgct
    66301 tgtccaataa cgtcttttcc agctaatgct agtggaatcg tttctgcttg gataggcgtt
    66361 gcttcttcaa aaccagcgcg ttcgactgat ttcaacaatt ctggtgataa ttctagttct
    66421 ttaaatttca aatgaatcct cctatatggt tgttaactga ggatgtagct tttttgctac
    66481 cccgtcgatt tgttcggtca aagtgtattg tttctttttg acagtggcca cgcacgtttt
    66541 tatccattct tagcccctgt ggcaccaccg aaaaatcact ttgcgaagtt taggcattag
    66601 aaaagccaaa cgggtcgcgt tcagctttat cattattatg acatctggct tcaacaagtt
    66661 gtttctatgg caaaaccagt ccaatttctc ttcatctttc ggcaataggt tattctaaca
    66721 tagtttttcg ttttctgcaa gtttacagat ttttatttca tttgctgaag ttgttctacc
    66781 acttcaaata agcccatgct gttgctgcct tttagcataa tactatctgt tgcttcaaga
    66841 ttttgtttga tagcatcaat caatttattc ttttcttttt caaaatagaa cacaggtagt
    66901 tgggggtatt tttggttcaa ttcttctttt agtgcatgca tttgttcccc ataaaggaaa
    66961 atcatggcga atttctcagg atcgatatgt tcactcattt gcgcatgcat atttaaagac
    67021 tctttcccta attccagcat atctgctaac acagcgattc tgcgtccttt tgttggcaga
    67081 tttttaaaag tatctaatac cagtcccatg gctgttggat ttgcattgta gacatcgctc
    67141 aaaatagctg caccatttcc tgccgttagc cattcggttc tgttttgagt gatagaaaca
    67201 tgggcgagcc cttggcgtat ctcaggtatg gacagtccaa agaagcgccc gatcgtatac
    67261 gcaatcaaag cattcgttac attataactt ccaggcagcg ggatcgtaaa tgtttctcct
    67321 tctactacaa aatcggtttg tgcttttcct tttgctgtca cttccgcatg aacatcgcca
    67381 tttccaatac cgaatgttgt gactgtttgt actaatgttg ccgttaaagg tgtcagcaac
    67441 ggttcatctg cgggcacaac gagtaatccg tctgatacaa gtccgtcagt gatttccatt
    67501 ttggctttag cgattccttc tcgcgaccca agattttcta tgtgtgcttc accgatcatt
    67561 gtgattgctg cagcttttgg ttgagccata agtgaaagtt ccgtgatttc attggcgtga
    67621 tccatgccca tttccaaaac gatcttttct gtatcttggg gcatgtgcaa aatcgtgtaa
    67681 ggaagaccaa tattattgtt gtaatttcct tgcgtcttat atgttttgta tttttcagac
    67741 aagacagacg cggttagatc tttcgtggtg gttttaccat tgcttcctgt aattgcaacg
    67801 acttctgcgc ctactttttc caagtaatag gttgccaatt gctgcatggc tttcaaagga
    67861 tctgctacag gaataactgg aaaatttttt ggagcttgtt caacaggcaa gctccaaaat
    67921 gaagcagatg ctccgtttgt gatcgcttgc tggataaatt catgtccatc tcgcgtacca
    67981 gcaagaggaa cgaataaact tccttcggtt atcttccggc tgtcaaattc gacattggta
    68041 atctttgtca gtgcagagca ttcgctgccc acggcttgtg caatttcttg tattgttaga
    68101 ttcattgaga tctctcctaa aaaaggttgt gaaaaaagcg tttggcctaa acggcgggtt
    68161 cgcatgactc tcacttccaa gtaaatttct ctattcgtat ttagaagcta gaatgaacgc
    68221 ggttacgcaa tcactccagc ctcttcttta tttctcttta ttcatttttt tcaaaaaaag
    68281 attgacgctg atggtatcga ttcattccta actggatcag ttcttcaatc aaatcaccgt
    68341 atttcaagcc catattttcc cataagagtg ggtacatact gaactccgta aatcctggca
    68401 tagagtttaa ttcattcagg aataattcat ttttatttgt caaaaagaaa tcgcaccggc
    68461 tcaatccgct tccacctaac atcgtgtaag ctaacttcgc gtactcttgc gctttttgat
    68521 aaacttcttc tggcacttcg gctggaatct gcatttcgat tttattattg atatattttg
    68581 cttcataatc atagaatgct acgtctttta cgacttcacc aggcaaagtc gtccgaacgt
    68641 cttcatttcc taatacagca acttcgattt cgcgcgcttc aattccttgt tcaacgattg
    68701 ctcgagaatc atactgatag gctgttgcta aagcattttg cagctcttct cggttttctg
    68761 cttttgtaat gccgacacta gaacccatat tcgccggttt gacaaacatc ggataaagca
    68821 aagaaccttc acattgatca aatacttttt taggattttc tttccattga ttcttaagta
    68881 ctggtacata aggaacttgc ggcacaccag cagcttgtaa aatatacttg gtcatgattt
    68941 tatccatggc acatgcactg gtcaatacgc ctgcgccgac ataaggcata ttcaatgtct
    69001 ctaagaagcc ttggatcgtt ccatcttccc cgtttggccc atgtaaaact ggaaaaacga
    69061 tggctccttc ttctttgatt tcgcccggat tgatcacttt tcctgtaaag ccttcctctg
    69121 tctgtccact tgggtcccat gaaagatgca agacatcttt gctggcaggt ttttctgtta
    69181 gtaatggacc tttgacccat tgtccttctt ttgtaataaa tacgagttga acttggtaat
    69241 aattataata aatggcattt aaaactgaaa atgcggaaag aatggacact tcatgctctg
    69301 cgctgcgtcc gccatatagt aaagtaatct tcaaaagatt gtcctcctgt attctaaatc
    69361 gttcagtgat ttactctcat attttagcac aaaacaaaaa taaacgaata acttatttat
    69421 aaaaaaacga gccagcttct aaaagaacga gcgtcattta ttttttgtca gctagattat
    69481 ttgtcccgtt ttttataaaa agttatgata aagaaaagga gggatgatga tggcgcaaac
    69541 aaatccacgc agccgcttgg cagaaatcat tcgagtgttc atcaattaca atgtagtgcc
    69601 aaactttgta cagcaaaaaa atcccgaaca ggtaaaaaaa gcctttgaag aactaggccc
    69661 caccttcatc aagataggac agatgctttc tgttcgagaa gatttgcttt cttctgcctt
    69721 cactcaaaca ttcaaaacat tacaagatag tgtacctagc gacacatttt caacggtcaa
    69781 aaagacgatc gaaacagaac tttctctttc attatcagat atattcgatg atttttcaaa
    69841 atcgcctttt gcctctgctt ctatggggca ggctcatcgt gccaagctga agaacggtga
    69901 cgcggtagtc gttaagatcc aacaccctaa catcgccgaa gagatccgac ttgatcttca
    69961 actatttgaa cgagcgatcc ctttgatcaa atacattcct gaaactagcg tagttgatct
    70021 aaaaggggta ctccaagaag taaaacgttc cttgatcaat gaaatggact tcttaaaaga
    70081 aagtcaaaat ggcgaacaat tctatcaaaa gaacaatggc tggaaagaga tccgcagccc
    70141 caagatttat gacgcttttt gttcgaaaaa agtgatcgtg atggaagaaa tgtctggtaa
    70201 aaacttgaat catttaatga acgccgaaaa caaaactgaa acttttatca ctggaattca
    70261 aaacaagcag ctgaaacaag aagttgcaaa gcttttagtt gagaacttta tgaaacaggt
    70321 gtttgatgat ggttttttcc atgctgatcc tcatccaggg aatctgctat tccatgtact
    70381 aacaaaagaa gaacagacac aagctagccg aaaaactgaa acagtccatg aaaaagagtt
    70441 cggttccttt gcttttcgag cctccacttc tgcagaagac cctgttgcgc catataccat
    70501 caactacatc gattttggta tgatggggca tctttctgca ggacttaggc aaaaactcac
    70561 acaagccgtt ttagcgctgt atacgaaaga tgcttatcga atcgaaaaag cggtccttcg
    70621 actttgtcag caagaaggct cgtttgatga aagtcggttc caccaagaac tgacaagttt
    70681 tcttgaacag tattatgatt ctcctattga tgaaatcaac ttgcaagaag tattcacaca
    70741 tgtcgtgacg atttgtcatc aaaataatct gcagttcgat cgtgatatca cgcttttgct
    70801 gaaagcattt gggacattag aaggggtgat ccgcgtcctc gatcctgaag tttccctcat
    70861 ggaagtcgct tcgccttttg ctcaacatta ttttctcact catctggatg tagaagatac
    70921 attgaaacaa agcggattag acttattgga agggatgaag gctgcgccta agatccctca
    70981 acagctccac catctattag aaatgtggac ttcgggacaa ggaaaagtca atttggaatt
    71041 gaaaaagcaa gacaaattat tgagcaggat cgaaagtatg atcaatcggc ttgttttcgg
    71101 tatgatttta gctgcattga tcgtagggtc ctccctgctt gtccaagcag cacctgtaga
    71161 aaacgcagag gtcgtttcct tattagggat atttacgtat gctattgccg cattcgtcat
    71221 tatttttttg gcaatcgatg cattgatcca aatgtataag aagaggaaaa agtagaaaaa
    71281 ggttgtgaca gaaagaatca gcttcaagaa ataagaaggg gttttacata aattgtttct
    71341 caaatttttg tgaaaattcg gcttattttt cgaagaggct acttctgaaa caccgagaat
    71401 aaaaaatgtg aaaaagctgt tctgcaccca gtaataagaa caatcaaaaa gggaacatgg
    71461 aacacattta tcctgtttcc ctgttccctt tttgatgtat tcgagcataa ataaaatacc
    71521 ttcgttacct actatcttct gtacttggta aaccttagtc aattgccttt tttaacgctt
    71581 gacgaaaaga catatgatct ttctccgtaa agggttttgg accctttgtc cttatgccag
    71641 cttttcttaa ctttccacta tgataacgtt gttctagaag cgtgccgata ttcgcttcgt
    71701 caaattcttt tccagagtga tggaacactc gcacaccctt cggcaataca agtgaagcta
    71761 aaccataatc ttgcgtgatc aaaaagtcat tcttcttaac cataccgacg attttataat
    71821 ccgcactatc agctccgcgg tctacgtaga cgatttggac atgattagcg tattctttgg
    71881 tcgtataatg gtccacactg gtcacgataa ccacgtcaag accataggat tctcctaatt
    71941 ttatgacatc ttcttttact ggagaaccat ctccatcaat gaatagcctc attctttttc
    72001 gccttcttcc ataaatgata aacagttact aatccgctca gtaaaagacc aacattgatc
    72061 cattttgcca agataagcag ttgtacactt tctatcggca ctgattcatg gttcagcgtg
    72121 atcaataata gatggattgg ctctcccatt tcttttgcta aaacaaacaa aagcgtcatc
    72181 aataaaaact ggtggatcac actcccttta ttttgagtag tatacttgac aacgatccgg
    72241 cgatccattg gaatagctgt atcagtttga taatattcct tatttagcca gctgcctgtt
    72301 actacgtgcc agaaactaag cagaaagaca cctatcgcaa aaccatttgg aatcaagagg
    72361 accaataaag aagaactcag tccaagcaat tgcatagcca atggagacca tgttaaacgt
    72421 ttcaaaatcc atggtccgac tatttttgct gcaatcaagc ctgctgcata aggcaaatac
    72481 ataaaaatcg aaagtttttc taatccgtac agtatgccaa cataaaaact gctaaataaa
    72541 aaaaggaaat tccctagcat tccatttaga aaagtaaaca gatttagcca gcttggcaac
    72601 ttccattcct tcttctggtg tcctaaaaca aacacgaaca agatgaacag cagcaagaaa
    72661 ccataaatag caagatcaaa aagcctttca tcgaataaca atcgggcatt tctcaaaaga
    72721 aacaataagc caaagaatat caaaaataaa acaagctctc gcgtagctac cagatttctt
    72781 ttgatgtctt tgaaatccag ttcgtaacgc ggataatgac taaccgtatg gtaggccatg
    72841 acgtaaaaaa gtgtataaat agtaaagctt gctgcaatct gagtcggtgc aggcaactca
    72901 atcgcttgat acaggagaaa tagccagata gctgcaaata agtacttttt cccatccata
    72961 ttgataaaac cttgcgtctt ttcgtgaaaa ttgaccgtgg tattagcagg tacaagccat
    73021 gctgcactca gccctagcaa aacacttgaa aaataaaata aaggaaaata aaatacgcct
    73081 aatattccaa gcaatgaacc agcaccacca atcagcagag cgatcatcag caacgtgtaa
    73141 ctatctagac caaatcgtag actgttgact aaaaatagtc cagtcatccg aaaggcataa
    73201 aacagcgtaa atggcaaaat cgtcagccaa ttatgcgagt ctgttagtcc caaaaataaa
    73261 agataaggaa taaaaataac cgtgttactt aagataaagg gcgttgtttg tgtaaaatta
    73321 cgcccaaatc gtttgagttt ttcgaacatg acaatggctc cttaaacagt cttataacta
    73381 atctgctctt cgattttagc attaaagggg aaataaacca attttacaga atatattctt
    73441 gtaaaaaaaa atacagaaag aagcataagc ttctttctgc atttttacgg tacttgatta
    73501 ctcaagcaga caagcccttc tccacaaaag tcttgcccga cacccctgca tccggcaggt
    73561 gataaagata gaaatcaatt atcctgtgcc tccaaaatca attaggagct ctgtaaacca
    73621 gagtccttct cgacccgtcg cataaattta ctttaacaca gttcctatgt ttatgcgaga
    73681 gcttttttca ttttataatc gaccatttga aatccttgac cgatatctga aataagttct
    73741 tctgtaatct caaatccttc atgcttataa acctcgattg cttgatgatt cccctgattc
    73801 actcgcaaaa agatctctct ttcctttgtt tgcgcagcaa gttcttcata ccagcgaaaa
    73861 actgaagaag tcaatccttg accacgtact ttatttagca aatataattt acttaaataa
    73921 atttttccat ttatctcttc ataagcagtg taaccgacag tcttttcttc gctttttaat
    73981 aaaaagtagg acacaccttc tgtcagttct ttttgaatct gtttttttga ctgataagtt
    74041 ttcagcatgt aatccacttg tttttgacca atgatcggca caaaaacttc cggccatact
    74101 tcttgtatga ctgccatcag ctcatccagt tcattttctg ttacttttat tttttccata
    74161 cacccacgtc cttttttaca ttataaatga ccttgcgctt gatggaataa aaagagcatg
    74221 atcatgctat acacacccac cgaccacggt ttcaagaaaa tcacaatctg cataaattcc
    74281 ctaaaagata atttcgtcaa accagctact agacagatca agtcgtctgg cgcaaaggga
    74341 agcagcaagg taacaactag tactttttta atatctttcg tttttcttgt cagcaattca
    74401 tcaaatttct gatacttttt tggcgataaa ataagctgga caaaggctac gccatagtaa
    74461 cggacaagca aaaatccgat tgcttcccca atcactaggc caatacaact atataaaagc
    74521 ccaaatccat tgccaaacat cagcatgccc gctactgagg agatccctcc cggcaaaata
    74581 ggaatgatca cttggatcac ttgcaacaga acaaatatca tcactgcata cttgccaaat
    74641 tgctggataa acgcttgcaa agacgtgctc gatcgaaaaa tcccatgatg ataagcataa
    74701 agaatcaaca caaagaaaaa aaacagacca ataatgggca tgatctgaag acatttttgt
    74761 aaaactgatc cttttttaga catctatatt ccccacatct tttttcattt attaaaactg
    74821 cctcct
//
LOCUS       DADVXK010000004        66795 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.004, whole genome shotgun sequence.
ACCESSION   DADVXK010000004 DADVXK010000000
VERSION     DADVXK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.004"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(132..509)
                     /locus_tag="KB909_000223"
     CDS             complement(132..509)
                     /locus_tag="KB909_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836288.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="KB909_000224"
     CDS             765..1493
                     /locus_tag="KB909_000224"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBB6836289.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="KB909_000225"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="KB909_000225"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBB6836290.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="KB909_000226"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="KB909_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBB6836291.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="KB909_000227"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="KB909_000227"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBB6836292.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="KB909_000228"
     CDS             4628..6067
                     /locus_tag="KB909_000228"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBB6836293.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6090..7142
                     /locus_tag="KB909_000229"
     CDS             6090..7142
                     /locus_tag="KB909_000229"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBB6836294.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="KB909_000230"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="KB909_000230"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBB6836295.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="KB909_000231"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="KB909_000231"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBB6836296.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="KB909_000232"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="KB909_000232"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBB6836297.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="KB909_000233"
     CDS             10661..11575
                     /locus_tag="KB909_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6836298.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="KB909_000234"
     CDS             complement(11708..13273)
                     /locus_tag="KB909_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6836299.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="KB909_000235"
     CDS             complement(13266..14717)
                     /locus_tag="KB909_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6836300.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="KB909_000236"
     CDS             complement(14731..15747)
                     /locus_tag="KB909_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6836301.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="KB909_000237"
     CDS             15967..17055
                     /locus_tag="KB909_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBB6836302.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="KB909_000238"
     CDS             17109..18635
                     /locus_tag="KB909_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBB6836303.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="KB909_000239"
     CDS             18637..19842
                     /locus_tag="KB909_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836304.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="KB909_000240"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="KB909_000240"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBB6836305.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="KB909_000241"
     CDS             21340..22764
                     /locus_tag="KB909_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6836306.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="KB909_000242"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="KB909_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBB6836307.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="KB909_000243"
     CDS             24337..25314
                     /locus_tag="KB909_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBB6836308.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25339..26982
                     /locus_tag="KB909_000244"
     CDS             25339..26982
                     /locus_tag="KB909_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBB6836309.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26990..28396
                     /gene="lpdA"
                     /locus_tag="KB909_000245"
     CDS             26990..28396
                     /gene="lpdA"
                     /locus_tag="KB909_000245"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBB6836310.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28558..28833
                     /locus_tag="KB909_000246"
     CDS             28558..28833
                     /locus_tag="KB909_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBB6836311.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28839..29606
                     /locus_tag="KB909_000247"
     CDS             28839..29606
                     /locus_tag="KB909_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBB6836312.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29774..31603
                     /gene="typA"
                     /locus_tag="KB909_000248"
     CDS             29774..31603
                     /gene="typA"
                     /locus_tag="KB909_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBB6836313.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31864..33636
                     /gene="recQ"
                     /locus_tag="KB909_000249"
     CDS             31864..33636
                     /gene="recQ"
                     /locus_tag="KB909_000249"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBB6836314.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33750..34052
                     /locus_tag="KB909_000250"
     CDS             33750..34052
                     /locus_tag="KB909_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBB6836315.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34055..35218
                     /locus_tag="KB909_000251"
     CDS             34055..35218
                     /locus_tag="KB909_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6836316.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35244..38672
                     /locus_tag="KB909_000252"
     CDS             35244..38672
                     /locus_tag="KB909_000252"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBB6836317.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38693..39817
                     /locus_tag="KB909_000253"
     CDS             38693..39817
                     /locus_tag="KB909_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836318.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39807..40244
                     /locus_tag="KB909_000254"
     CDS             39807..40244
                     /locus_tag="KB909_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6836319.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40228..40566
                     /locus_tag="KB909_000255"
     CDS             40228..40566
                     /locus_tag="KB909_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBB6836320.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40685..41245
                     /gene="rsmD"
                     /locus_tag="KB909_000256"
     CDS             40685..41245
                     /gene="rsmD"
                     /locus_tag="KB909_000256"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBB6836321.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41242..41733
                     /gene="coaD"
                     /locus_tag="KB909_000257"
     CDS             41242..41733
                     /gene="coaD"
                     /locus_tag="KB909_000257"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBB6836322.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41723..42766
                     /locus_tag="KB909_000258"
     CDS             41723..42766
                     /locus_tag="KB909_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBB6836323.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42925..43653
                     /locus_tag="KB909_000259"
     CDS             42925..43653
                     /locus_tag="KB909_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBB6836324.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43769..44014
                     /locus_tag="KB909_000260"
     CDS             43769..44014
                     /locus_tag="KB909_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6836325.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44011..44229
                     /locus_tag="KB909_000261"
     CDS             44011..44229
                     /locus_tag="KB909_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBB6836326.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44365..44904
                     /locus_tag="KB909_000262"
     CDS             44365..44904
                     /locus_tag="KB909_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBB6836327.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44897..47170
                     /locus_tag="KB909_000263"
     CDS             44897..47170
                     /locus_tag="KB909_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBB6836328.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47208..48254
                     /gene="holA"
                     /locus_tag="KB909_000264"
     CDS             47208..48254
                     /gene="holA"
                     /locus_tag="KB909_000264"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBB6836329.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48343..48597)
                     /locus_tag="KB909_000265"
     CDS             complement(48343..48597)
                     /locus_tag="KB909_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBB6836330.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48997..49266)
                     /locus_tag="KB909_000266"
     CDS             complement(48997..49266)
                     /locus_tag="KB909_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836331.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49736..50191)
                     /locus_tag="KB909_000267"
     CDS             complement(49736..50191)
                     /locus_tag="KB909_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBB6836332.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50329..52257)
                     /locus_tag="KB909_000268"
     CDS             complement(50329..52257)
                     /locus_tag="KB909_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6836333.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52454..53287)
                     /locus_tag="KB909_000269"
     CDS             complement(52454..53287)
                     /locus_tag="KB909_000269"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBB6836334.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53479..54183)
                     /locus_tag="KB909_000270"
     CDS             complement(53479..54183)
                     /locus_tag="KB909_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6836335.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54206..54832)
                     /locus_tag="KB909_000271"
     CDS             complement(54206..54832)
                     /locus_tag="KB909_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6836336.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55158..57533
                     /locus_tag="KB909_000272"
     CDS             55158..57533
                     /locus_tag="KB909_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBB6836337.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57557..58048)
                     /locus_tag="KB909_000273"
     CDS             complement(57557..58048)
                     /locus_tag="KB909_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBB6836338.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58235..59155
                     /locus_tag="KB909_000274"
     CDS             58235..59155
                     /locus_tag="KB909_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6836339.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59309..59653
                     /locus_tag="KB909_000275"
     CDS             59309..59653
                     /locus_tag="KB909_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBB6836340.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59843..60343)
                     /locus_tag="KB909_000276"
     CDS             complement(59843..60343)
                     /locus_tag="KB909_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836341.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60871..60954
                     /locus_tag="KB909_000277"
     tRNA            60871..60954
                     /locus_tag="KB909_000277"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60905..60907,aa:Leu,seq:cag)
     gene            complement(61278..61916)
                     /locus_tag="KB909_000278"
     CDS             complement(61278..61916)
                     /locus_tag="KB909_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6836342.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            62251..62685
                     /locus_tag="KB909_000279"
     CDS             62251..62685
                     /locus_tag="KB909_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6836343.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            62708..63028
                     /locus_tag="KB909_000280"
     CDS             62708..63028
                     /locus_tag="KB909_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836344.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            63169..63360
                     /locus_tag="KB909_000281"
     CDS             63169..63360
                     /locus_tag="KB909_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836345.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(63431..63688)
                     /locus_tag="KB909_000282"
     CDS             complement(63431..63688)
                     /locus_tag="KB909_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBB6836346.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            63846..64109
                     /locus_tag="KB909_000283"
     CDS             63846..64109
                     /locus_tag="KB909_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836347.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            64133..64321
                     /locus_tag="KB909_000284"
     CDS             64133..64321
                     /locus_tag="KB909_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836348.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(64404..64589)
                     /locus_tag="KB909_000285"
     CDS             complement(64404..64589)
                     /locus_tag="KB909_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836349.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            64804..65175
                     /locus_tag="KB909_000286"
     CDS             64804..65175
                     /locus_tag="KB909_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6836350.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(65325..65397)
                     /locus_tag="KB909_000287"
     tRNA            complement(65325..65397)
                     /locus_tag="KB909_000287"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(65362..65364),aa:Gln,seq:ctg)
     gene            complement(65443..65871)
                     /locus_tag="KB909_000288"
     CDS             complement(65443..65871)
                     /locus_tag="KB909_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836351.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(65931..66689)
                     /locus_tag="KB909_000289"
     CDS             complement(65931..66689)
                     /locus_tag="KB909_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBB6836352.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT        22015 a        11449 c        14210 g        19121 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc
    25381 gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat
    25441 acattactag aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga
    25501 acggttaaaa atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta
    25561 gaaatcgatg caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc
    25621 caaactccag ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca
    25681 agcgaaggag tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa
    25741 atcgtcaaat ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa
    25801 gttcaaaatg acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac
    25861 gtgattgttc cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct
    25921 cctggacaca atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa
    25981 gtggaaacat caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg
    26041 gctatgccat ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact
    26101 gcaactggaa aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt
    26161 ccaagcagtg caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct
    26221 cctgcagcag aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac
    26281 ttggaagaac gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac
    26341 agtaagcata cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg
    26401 gataatcgga aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg
    26461 ccatatgtcg tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct
    26521 atcgacgatg caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact
    26581 gatacggatc acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt
    26641 gctattgcag acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca
    26701 gaagatatgc gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg
    26761 tttacaccag tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa
    26821 caaccaatcg taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta
    26881 agtttcgatc accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa
    26941 cgtcttttag ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg
    27001 agattttgct gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc
    27061 tgccatccgc gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg
    27121 cggtgtttgt ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca
    27181 ttatcaagag tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga
    27241 ttttgcaaaa acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt
    27301 tggtttccta ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga
    27361 tgatcacaca ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc
    27421 aatcatcgca acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt
    27481 gttagattct actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg
    27541 tggcggtgtg attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac
    27601 gattcttgaa ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt
    27661 agaagatgat ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc
    27721 agtcgataac ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt
    27781 tactgctgat tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt
    27841 agaacaagcg ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg
    27901 tacgaacgta cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca
    27961 caaagccagt tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt
    28021 agattataaa gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat
    28081 gacgatcaaa gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc
    28141 agggaacggt cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac
    28201 gatcgaagat aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt
    28261 ctctgaatta gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat
    28321 tcatcctcat ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt
    28381 accaatccat atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt
    28441 ttgtttttta gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg
    28501 gtttattacc acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg
    28561 caagaatatc agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg
    28621 aagatgtggg aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg
    28681 aagacttatc agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga
    28741 cgggaatttg aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa
    28801 aatccaaaca aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata
    28861 tcaagtcctg gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa
    28921 tctcgcaaaa atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt
    28981 ttctaatcga aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag
    29041 ggtgtaatca attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca
    29101 ccttgaattt tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg
    29161 gcgttggaaa gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa
    29221 aaggaatagg cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat
    29281 cggaaggctt acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag
    29341 aaattgcgga aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg
    29401 caatcttgaa aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag
    29461 cgggaaatgt cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt
    29521 tgacatttga aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg
    29581 cagacctttt gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa
    29641 aacgagcaaa agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa
    29701 aagtctgcta taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa
    29761 ggagttagtt acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt
    29821 tgaccacgga aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc
    29881 acatacgcaa ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat
    29941 cacgatttta gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga
    30001 tactccagga cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg
    30061 cgttgtgttg gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa
    30121 aaaagcactg gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc
    30181 tgctcgtcct gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga
    30241 tgatgatcag ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt
    30301 gtcagatgat ccagcagatc aagaaccaac catggcacct atttttgata caattattga
    30361 aaaaatccct gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact
    30421 tgactacaac gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa
    30481 agtaggagac caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac
    30541 gaaattattt ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga
    30601 cttgattgct gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga
    30661 tcatcaagat gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt
    30721 agttaataat tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga
    30781 agaacgtttg atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc
    30841 tccagatgca tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa
    30901 catgcgccgt gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat
    30961 cgacggtgta aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat
    31021 gggtagtgtt atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac
    31081 aggaaacgga caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc
    31141 aactgaattc ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata
    31201 tctgccaatg cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga
    31261 tacaggaaaa gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt
    31321 agaaccaggt acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga
    31381 tttgactgtc aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga
    31441 ccaaacatct gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt
    31501 gaatgatgat gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt
    31561 agagaaaaat gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag
    31621 agagaaacca gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt
    31681 ggagaagtca tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa
    31741 gacttttaaa aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga
    31801 aaggagatca acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg
    31861 aagatgaacg acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa
    31921 gaaattatcc agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt
    31981 gggaaatcaa tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg
    32041 tcccctttaa tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc
    32101 gccactttta tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc
    32161 gatagacagc agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt
    32221 atccaagcaa tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc
    32281 tctcagtggg ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa
    32341 ctgccaaatc gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct
    32401 gacataaaaa gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga
    32461 gaaaatctac gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat
    32521 ttaaagatca acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac
    32581 cgtctctatc atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta
    32641 aatgagaatg agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt
    32701 gtagcgacaa atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat
    32761 tatcaaattc ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat
    32821 ggtctttcca gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt
    32881 tttatccagc agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa
    32941 gcgatgacag aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt
    33001 ggcgagacaa gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta
    33061 gaagtaacga cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat
    33121 ggtaaacaaa tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta
    33181 ggttttggac atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg
    33241 cagttaattg aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct
    33301 gttttgaaag taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga
    33361 aaggaaccca agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg
    33421 ctgcgggaac tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt
    33481 tcagattcca cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt
    33541 cagataaaag gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg
    33601 ataaaaaatg cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa
    33661 taaaaacaac tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat
    33721 taaggaatta gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc
    33781 aagtattaaa tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc
    33841 tctgtatctc acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt
    33901 cccggcaagt cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga
    33961 tgttaagtga gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt
    34021 atgataaaaa agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca
    34081 tctattagac tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat
    34141 ggtatatagt tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt
    34201 cattaaccag agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat
    34261 gaaaacagat gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat
    34321 tttgctgctg attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca
    34381 aattgcagga ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct
    34441 gtctctgact ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa
    34501 acgtccactt gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg
    34561 taatgcggca gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta
    34621 tgtgtatact ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct
    34681 gatcaatatc acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt
    34741 tgctatttac caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg
    34801 ctactatgcc atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa
    34861 aaaaggattt ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact
    34921 gggagtgatt atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt
    34981 ccttgtaggt atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc
    35041 aatgtttttg atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac
    35101 agggatcacg ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg
    35161 tgtcggcttt gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata
    35221 aaaaaagatg taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg
    35281 ctgtacgtgt atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag
    35341 aagaagatga atattccgta caccgtttca aagcggatga agcatattta gtaggacaag
    35401 gaaaaaaacc gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat
    35461 gcggagctga cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc
    35521 aacggtgcga agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt
    35581 ttggagataa aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag
    35641 gcacagatgg accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt
    35701 atccgattat gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg
    35761 atgaaaagag tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg
    35821 gtagtgatga agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga
    35881 ttctcgggga tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc
    35941 gccgtcacca aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc
    36001 aaaaaatctg ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta
    36061 cagtagaatt tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc
    36121 aagtggaaca tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt
    36181 tgattgctca aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta
    36241 aattaaatgg ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt
    36301 taccagacac agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg
    36361 atgtcggaaa tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa
    36421 aagtatgtac gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga
    36481 aagaatttag aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac
    36541 atcctgaatt ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat
    36601 ttgaatttcc tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta
    36661 ctgtgaatgg ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta
    36721 tgcctaaaga tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga
    36781 agggtgccga tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata
    36841 cgacatttag agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca
    36901 agcagattgc acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg
    36961 ggggagcaac atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga
    37021 gaaaaattcg ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg
    37081 ccgttgggta ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag
    37141 cgcaaggaat cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa
    37201 aaagtatcca agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg
    37261 gcgatatcaa cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa
    37321 aggaactaga acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta
    37381 aaccgcaggc agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc
    37441 atctgcatac tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag
    37501 caggagtaga catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta
    37561 gcatgagcag cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg
    37621 aaaatgcaca gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg
    37681 aaaacggctt gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt
    37741 attcgaatct acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca
    37801 aacaaatgta tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat
    37861 ctaaagtagt tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata
    37921 tttatgaaaa aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag
    37981 aactagggca acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca
    38041 gacctgcatt gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa
    38101 aaaaagaatt ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt
    38161 tgatgtatcc gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta
    38221 cattactgga cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac
    38281 aaatcgaacg cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg
    38341 aagggaatcg cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag
    38401 ataattcgat catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac
    38461 aaattggagc aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg
    38521 ttaaaaaagg tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag
    38581 cacgttttga cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg
    38641 gtgacctttt gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag
    38701 actgggtttg ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt
    38761 cttgtttccg ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat
    38821 gacaacgtgg aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc
    38881 gatcgatcag ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg
    38941 ttttgaaaca agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca
    39001 agacagcaga gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt
    39061 ttatttaggg atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac
    39121 ttttgagtac catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg
    39181 tccgctaatt gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa
    39241 cggcctattt tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca
    39301 agtgtttggt gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat
    39361 caatcgcgtt aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga
    39421 acttcccata tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga
    39481 ttttttgaca aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc
    39541 gctaggcagt gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt
    39601 aatcagtaaa caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc
    39661 tactttttcg tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc
    39721 gggaacggat tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga
    39781 agaaaacgga gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg
    39841 atcaatgcct ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg
    39901 aacataaaca gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt
    39961 ctaagaaaga agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg
    40021 aaaaaaaacg agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag
    40081 ctttccgata tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg
    40141 ccgaagaagt ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa
    40201 aacactttgg atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca
    40261 aaacgacgcg ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag
    40321 ttcggcttgt tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa
    40381 gagacattgg aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa
    40441 cgttcttacc gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta
    40501 ttaaaagacg aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat
    40561 ctttaaaaat ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt
    40621 ttgatcattg tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga
    40681 gtagatgcgg ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc
    40741 gaacaccaga ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata
    40801 ttttgatgga gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc
    40861 agtatctaga ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat
    40921 catcaaagaa aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga
    40981 tgcggacaaa gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct
    41041 tgatccgcca tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg
    41101 acttttttct aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga
    41161 aactgtggct ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat
    41221 ctatagaaaa gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt
    41281 acaaaaggtc acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt
    41341 ggtgttttta tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg
    41401 atcacaaaag ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg
    41461 acggtagaaa cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc
    41521 aaagactttg aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg
    41581 gaaactgtct tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa
    41641 gaagtactgc actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct
    41701 ttagctggaa agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat
    41761 catatttgga atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc
    41821 accgggagcc acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg
    41881 ttctgggtct ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt
    41941 aaaagctaaa atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc
    42001 gacaaatgaa gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc
    42061 aatcgaacaa gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata
    42121 tgtcatgagt gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt
    42181 aacaaaagta gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag
    42241 ccaaaaagtt ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc
    42301 ttctggtgat ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac
    42361 tgaccatacc gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg
    42421 gccatcagcg ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt
    42481 gcgacatggt aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg
    42541 aatcggagga atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt
    42601 tgcaccagat gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa
    42661 ctacgaagaa gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt
    42721 aaaaacagta caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa
    42781 agaggggttg tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat
    42841 aaaaataaaa acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag
    42901 agctcactgt ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc
    42961 tttgaaaaaa gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg
    43021 atcatttgga tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca
    43081 aatttgctat tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt
    43141 agttccagtg gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca
    43201 aaggtcatgt acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct
    43261 tcagaagaac gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat
    43321 agcgatcgaa tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct
    43381 gtaggtgaag agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct
    43441 acagcagatt ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag
    43501 cagattcctg ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac
    43561 ggatccttcc agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt
    43621 gaaaaactaa aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc
    43681 aataaatgga cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag
    43741 gaggtagtat ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc
    43801 aatgctgaat gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt
    43861 cagcggcaat aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac
    43921 agcagataaa gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc
    43981 taaagaaacg taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt
    44041 tctgatcatg ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg
    44101 aataacaagt tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat
    44161 tgtgaagtat cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata
    44221 atgggctaat ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca
    44281 ggatgattcg ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact
    44341 tgaaaaaacg gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat
    44401 aaagaaaaag ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg
    44461 gctcaggcag tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca
    44521 ctcgttcgag aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc
    44581 cactgcatag atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca
    44641 gagatgaatg cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc
    44701 tatgtcacac attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa
    44761 gggatcaatt atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa
    44821 ttaggtgtat ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat
    44881 gaattaacag gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt
    44941 tccggcaatt acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg
    45001 tttgcttctt gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta
    45061 cttgtgtatt ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt
    45121 tttagaggaa aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa
    45181 tggtaatttt ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc
    45241 ttatcaagta aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat
    45301 agaattgact gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt
    45361 tgaccaagaa gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat
    45421 tgaacagatc accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt
    45481 tatctccttt gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt
    45541 atggggctat aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt
    45601 gctgcatctg ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta
    45661 tttgtttcga cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac
    45721 tatctgttat gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt
    45781 tttattgcga ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc
    45841 agttgtcttt tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca
    45901 gcttagtttt ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa
    45961 aaaaacggcc tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt
    46021 ttatgagtgg cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt
    46081 tctttttctt cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt
    46141 acttttgctg atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg
    46201 gtcgtctctc attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt
    46261 actgatttgt atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct
    46321 tttttctttt atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat
    46381 cgatgtcggt caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt
    46441 gatcgatact ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg
    46501 tcctcctgct gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga
    46561 taaactcatc ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca
    46621 gcattttact atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca
    46681 aaggcattta tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga
    46741 caggatcagc ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag
    46801 aaatgaagat tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg
    46861 agatttgaat caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga
    46921 tgtagtcaaa ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca
    46981 tattgaagca aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca
    47041 cagcgaagta ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca
    47101 aggaatgatc acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat
    47161 gatagactag taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt
    47221 tgagtataca agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga
    47281 ttttaggaac agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc
    47341 aattagaggg cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag
    47401 atgaggtagt agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg
    47461 tagagaatcc ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg
    47521 atttattgac ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc
    47581 catatgaaaa gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta
    47641 tcatcaatgt ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag
    47701 agaattcctc aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact
    47761 tagatttatc caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac
    47821 agcaaatcac ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt
    47881 ttgacatgac ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag
    47941 atttagttat gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac
    48001 gtttattttt acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg
    48061 aaacattgaa aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg
    48121 atgaacattt gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa
    48181 cgggacaaat cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt
    48241 taagaaatcg ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt
    48301 cctttttttg acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt
    48361 gcttaaacga gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc
    48421 catatcaata gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc
    48481 tacagcatct tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt
    48541 cacattagcg ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag
    48601 tttcacctcc gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt
    48661 atacctaaag gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct
    48721 tttattagga ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac
    48781 gctattgtgg gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa
    48841 agtttgaatg ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag
    48901 ttttttttga aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca
    48961 gttattttat aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt
    49021 aatgtattca tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt
    49081 ccatttgcca cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc
    49141 caaatagcga tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc
    49201 agtcagcatc attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt
    49261 ttccacaagc gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat
    49321 tttgatattc gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata
    49381 acaaaaaaga gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca
    49441 ttggcacggc ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc
    49501 atcccctata tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa
    49561 atcaggaaat aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc
    49621 gattgttcct atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat
    49681 cacggatcag taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt
    49741 ttcctaaagc aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg
    49801 cggcgattcc tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga
    49861 tttgtggatc agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac
    49921 cgcaaaaaac agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac
    49981 cgatttctcc tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat
    50041 tgattccttt gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa
    50101 tcaaaacaaa agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta
    50161 aaataattcc taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca
    50221 atcataacat gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat
    50281 aagctgtttt tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga
    50341 agacagccgc gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc
    50401 aggtaaaggt cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg
    50461 tcctacaact ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag
    50521 aataacaaga atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag
    50581 ccgatgactg tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc
    50641 catagcggca tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg
    50701 cgcatcattg actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt
    50761 gactagttgt gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg
    50821 ttcagcaatg gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt
    50881 ttgggattta aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc
    50941 taaaacagca attaactgct gatctttaga aagataaatc acggttttgc cttgattttc
    51001 caaacgttcg atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc
    51061 gtgcttgcca actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat
    51121 ttcttctatt ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat
    51181 cgcatgagca agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa
    51241 atccttttca tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc
    51301 tgttttatca aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt
    51361 gattaaaatc ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga
    51421 tgcgacaagc gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc
    51481 atcccaactc caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa
    51541 aatcaatttt acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt
    51601 attctgcgct tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt
    51661 tgttactcga atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc
    51721 taaatatttt tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg
    51781 tgtgctttct aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt
    51841 atccaccttt agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg
    51901 ggctttttgt ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt
    51961 gtattcctct aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta
    52021 attaccgatc aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt
    52081 ccgatcattc cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat
    52141 ggcactgata taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa
    52201 gatcataaat aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt
    52261 tattagacct ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac
    52321 agctaaatga gaacgataat ggttatcatt tggtgattaa gcttgatgtt gtttttatta
    52381 tttataatga ttattattaa agaaaataaa aaaccagaac atttctcaaa taagagaagt
    52441 gttctggttt tttctacatt gcaataaacc aataaccaat caaaatgata ccaaggataa
    52501 tacgatacca gccaaaagcg gtaaagtcgt ttttcttcaa atagcttagt aagaatttga
    52561 tagctaagac ggaaaccaca aaagatacga atgttcctac aagaagaaca acagtttctt
    52621 ccattttgaa tgaattccct tcagctaaat atttgacgat cttcaagccg cttgcgccaa
    52681 acatgacagg aatccctaag aaaaatgaaa actctgtagc gacaaaacgc gaagcaccaa
    52741 tcaagataga tcctaggatc gttgcgccag aacgggatgt tccgggaaca agtgccaaga
    52801 cttggaataa cccaacaaga agagctgctt ggtacgtaaa gtcattcaga gaagtccaac
    52861 gaggtgtttt gtttttgttg cgtttttcga caataataaa ggcaataccg taaacgatca
    52921 aaacaatggc aactggtaag aacttgtgga aatttgcttc taaccaatca tccaaaggca
    52981 aaccaatgat gatggctggt atgcaagcaa cgatcacttt aaaccaaagt gtccacgtat
    53041 cttttttttc taccgttgat ttacttggag aaaatgggtt taacttgtga aaataaagaa
    53101 cgacgacagc caagatcgcc cctaattgga taacgacatt gaacatcgac ataaattgtg
    53161 aactggcatc cagtttgatg aattcatctg ctaggatcaa atgaccagta ctactgatgg
    53221 gcagccattc cgttattcct tcaataatac cgagaatcac tgctttgata atatttgcaa
    53281 aaaacataaa ttccttcctt cccaattaag atacatctta tagtataccg ttattttttg
    53341 agaaacccaa tctgtttttt aatattaaga aaaacttgag aaataaagca gataagtaca
    53401 cgaagagaaa aaagaagaca aagccctcgt tcagactttg ccttttatga ttctctggta
    53461 aaaattaaaa tatccccatt atagaaacga gtcgcgacta tgtgttttcc cgttatcgat
    53521 ataagacgta tcattgatgc cgtggataga aaatcgaccg tttgcataag tgacctttgt
    53581 tacgctgcca tttaaaagcc cagcacgaac aggctgttta ggatcgatca gattaagcaa
    53641 aaaggcgatc gtcaaaccat gagatacgac taaaacattt ccaccaccat ttttttcgca
    53701 gtgatgggcg atatcttcaa atcctgtcca tacacggtct cgcaatgttt cataagtttc
    53761 cgcccaccca gcggtatcta agttgtatac agcattagca atttgttcaa aagaaacttc
    53821 tgtggtaaac atttcatcat atgttttaaa attcaataca cgagggatca caccccacat
    53881 ttccatgtca tatccacctt caagagaccc gaaacaccat tctctaatcc ttttttcaat
    53941 aaaataagga atttcttttc ccttagaatg ttctcctaga ataatacggg cagtttcgat
    54001 tgcacgacca ctgtcactag aataagcaaa tgaaaagtcg acatttttta acccgcgacc
    54061 taaataatga atgccttctt gtccttgctt tgtgaggggt gtatcacacc agccttgtac
    54121 tcgttcaatt gtattgaaca tcgtttttcc gtgtcgtacg atataaagtg tagtttctgt
    54181 cattttattc tcctcctaag tcgttttaac gattgaaaaa aggatttgtc cttttttcct
    54241 gttcaatcgt cgttgcatcg ccatgtcctg gatagactgc aaattcatca ggtaatacaa
    54301 acagctgggt ccgaatacta tgaagtaatt gttctaaatt ccctgtatac agatcggttc
    54361 taccgatact tcctctaaac agggcgtcgc cagaaacgac aaaatcatca aaaataaagc
    54421 tgacgcttcc tatagaatgc cctggggtag ggacgacgcg aaaagacatg tttcctaaag
    54481 tataagtttt catttcaaat tcatattctg caggcgagac aataacatca gcaatatcat
    54541 catgtctacc gagtccagaa agattcaaaa tcggatcacc tagccatttt tgctctagtg
    54601 ggctgacata aactgggatt tgataatacg cgcgtaaagg ttccactgca ccgatatgat
    54661 cgtagtgagt atgggtaagc aaaatcgcta ccggctgttg gtttgttttt ttgatttctt
    54721 gtttgattcg ttccgcatct tctccagggt caatgatcaa aagtgcttct tcgttgtaga
    54781 ccaaataaca gttttcttca atcattcctg tttttaatct ttcgatatgc atgtgcattc
    54841 ctccttgata gccaaaactt ctttcatcca ttagtataac gcattcattg ctaggaaaca
    54901 aaaacaggta cttatttctc tttacttatc tgaattatca gactatatga aaagtatttg
    54961 gatattctaa agagaaggaa agtaagtttt catagcattt taatatgtcc ttgttacatt
    55021 agattcatcc aaaaatccaa attctatatc ctatatccct gcctaatcag cagggtgttt
    55081 ttttatgttt ggaaagagag ctctttttgc taaactaggt tttttcaggt aatcttagag
    55141 agaaagaggt ggtggaaatg atcaaacagt caaaaatatc tgtgcggcac ttagtagaat
    55201 ttattttgcg acgtggaagt atcgacaatc gtaaaaaaag taaccatact gcattagaag
    55261 gagcgagaat ccaccgcaag ctccaaaaag atgcgggaga aaactatgaa aaagaagtct
    55321 ttttaaaaac aacagttcaa ttagatgaat attacctgat cgttgaaggc cgtgcagacg
    55381 gtattttcaa aagagacggt atttattata tagatgaaat caaaacctcc gaaccacgat
    55441 ttgaagattt agaaccagaa caagtggaac ttttctttca tcaagcaagg gtgtatgcct
    55501 atatctatag tcaagaacat gatttacaag aaataaatct gcaattgact tacttccaga
    55561 cggcagaaga agtgatcacg agaaaggttg aacatcagac aagagagcag ttagaaactt
    55621 tttttaaaaa gctgactgaa gattataaag aatggcttgt ttttcaagaa aactggcgca
    55681 ctgtacgcaa tgcctctttg atggctttga aattccccca tgatgagtat aggaaaggtc
    55741 agcgtgaact agcggtagct gcttataaaa cgatccgtac gaaacagaaa ttgtttgtag
    55801 aagcacctac cggaacagga aaaacaatct ctacgttatt ccccgctttg aaagctgtag
    55861 gggaagaaga gggagaaaag atcttttatc taacggctaa aacaataact agacaagtag
    55921 ctgaagatgc tatgacagca ttaaaagata caggagctga agtaaaaagt gtcactttga
    55981 cggcgaaaga caagatctgc tttttagatg agacgacctg taatccagat cagtgcccat
    56041 atgccaatgg ttattacaat cggattaatg aaggtttatg ggatcttttg aatcatgaga
    56101 atcagatcac tcgtgaagtc atcgaaactt atgcaagaaa gcatacactt tgtcctttcg
    56161 aactatcatt agatgtcagt atctggtgtg acgtaatcat tggggattac aattatttat
    56221 ttgatccaac tgtttattta agacgttttt ttgaagatga aaaaaacgag gactatctgt
    56281 ttttgattga cgaagcacat aatttggtga atcgttcccg agagatgtat tcggcagaac
    56341 tatcttatga aaaaacgaaa cgaagtaagg aagctatacc aaaggaattc aaaaaacttc
    56401 atcgccgttt caacaaacta ttaaaagaat ttgattcgat ccgagaaata gcaaaagaag
    56461 atcattggga ttatcatcat caaaaagcac cggctgaatc tttagtaaag gcaggttatc
    56521 aattaagcga aaaaattaaa gaatggctgg cagaatttcc tgagcaccca tcacaagaac
    56581 aattgcttcc ttattatttt gatttgcttc attttttgaa ggtcagtgaa ttttatgatg
    56641 atcactacga aacaacagtc gaaaaaacgt atcgcgatct gatagtaaaa gagttttgta
    56701 ttgatccaag cttgtttctt gagcagtcgt tggataaagg aaaaagcagt attctttttt
    56761 ctgctagttt ttcaccactc tcttattatc aggaaacact ggggggacaa aaaagtctgg
    56821 cttacaaact gccgagtcct ttcccagaag gaaaccagca agttttcatc gcaaattacc
    56881 tagagacgac ttatcgaaaa agggaacaca gtctggcaaa attagtagag acgattcatg
    56941 cttttgctga tggaaaggtc gggaattatt tcgttttctt tccttcttat caatatttag
    57001 atcttgcggt ggaagcattc agacagcaat atcccgacag caatgtgcta atccaagaaa
    57061 cggacatgaa tgaggaagaa cgcgaacgat ttttaacaaa atttcaaaca aatcccgctg
    57121 aaacattgat tggattttgc gtacttggcg ggattttttc agaaggaatc gatttgagag
    57181 gggaccgatt gatcggcagt atgatcgtag gtgtaggttt gccgcagatg aatcatgagc
    57241 aggaactgat caaatcatat tatgatgaga aggaacacct tggatttgct tacgcttatc
    57301 agcttcctgg aatgaacaaa gtcttgcaag ctggtggtcg agtgattcgt ggcatggcgg
    57361 atcaaggaat cgttgtattg gcagatcaac gattttctag tttttcttat cgacgtttat
    57421 tcccacaaca ttggcaaaca gcaagagaag tacgaagtgt tggggaattg gaagaaggaa
    57481 tacagcgttt ttggttatca aaagaagcag taaatcaaaa aaacgaggaa tgacagacgt
    57541 cagcctcgtt ttttgattaa cgatagttag tgaattgcaa ctcgattggt aagtcaagtt
    57601 tacgtaataa agcaatcaca gcttgtagat catcacggtt cttacctgtc actctaatct
    57661 gatcttcttg gatttgtgct tttactttca gtttttcatt tttgatagct gtagtgattt
    57721 tcttcgcgtt ttcacgatcg attccgttga ccaaatcggc agtttgtcga gctttgccac
    57781 ctagagcgtg ttctgattcg gaaaaatgga tatttttgat tggcacattt cttttgatca
    57841 gcttaccaaa taatacatct ttgatctgtt cgattttgaa atcatcatcg ctcaatacaa
    57901 ctagattgct gttctctaat ttgatttcta ctgtagaatc cttgaagtca aagcgattgg
    57961 acaattcttt tgttgtttgc tgaatcgcat tttttacttc ttctgtattg acttctgata
    58021 caatgtcgaa gctagcatct tttgccatag gaaccctcct gatatacata taaatattta
    58081 ccatacatct atcttatcat aggattaggg cagattctta cctgtttgct aaaattcttc
    58141 tcatttgagt tcgaagtatt ttattttaat agataaactg ttattcttac atttggaata
    58201 ccaaagtagg ggagaggtgc ttgtgagtaa aattatgact gcgtatcata aaaatgaaag
    58261 attaaagaaa atagtggtta ttttgataac cggattgacc gctgcggtcg ctttaaatta
    58321 ttttttgatt ccagccaatg tcttttctgc agggatgaat gggatcgctc aaatcatttc
    58381 ctcgctttta tatgaatggt ttcatatcaa gatagacaca ggaacattta tttttctttt
    58441 gaatatccct gtgtttgtat tagggtttct caaagtagga aaacgagcaa cgatccttag
    58501 ttttgtgaat gttgtatgtg tatcggtgat gacgatgctg cttccagtcg gacagatcac
    58561 tgataatatt ttgatgaatg ccctagtagg cggtgtttta ttaggtcttg gcgtaggatt
    58621 atctttaaaa atgggcttta caactggtgg gatggatatc atctctcttg tactttcaca
    58681 aacaactgga aaaacagtcg gaaactacat gctgattcta aatggtatca ttgtagtcat
    58741 cgcaggcttc ttctttaact gggaaagtgc cttgtatacg attatttcca tttatgcaat
    58801 gactcaagta attgatgcca tccacacgag tcatcaaaaa gtaacagcaa tgatcgttac
    58861 cgtcaagcca gaagaggtaa cagaagaact agcaaaacgg atggtacgtg gaatgacatt
    58921 actgccgtct gtcggtggct attcaaaaaa acaagggaac atgatcatga tggtcatcac
    58981 ccgctacgaa atgtatgatc ttgatcagat cgttcatgaa atcgacgacg atgcatttat
    59041 caatatttta ccaactcatt cagtatttgg ccggtttgca aatgaaaacg aacaaaaaat
    59101 gtatcgaaca actggcgtat tgccagaaat aaaaaatcgt tcacaaaaaa aatgaggaat
    59161 caggtttatt ttagaataaa tttaatctat tacatctaat aagaacattt ttataaattt
    59221 aaacgagaat cttacttcta aattctcatt tacaagcagc taaaaaaaga gtatgataaa
    59281 taaaaatcgt gttaaggagt gtcgtacgat gagcgaagca aaccaagaac ggtctggaca
    59341 agaaatagaa ctaatcaaag aacgtattct tgctgccttg gaaatggtga ttgatcctga
    59401 attaggaatc gacatcgtca atttaggctt gatttatgat atagaattca atcctgaaaa
    59461 tggagaaaca gtcattaaga tgactctaac aactatgggc tgtccattag cagatatttt
    59521 aacagaatct atccatgacg cattaaaaga agtgccagaa gtaacgaaag cagaagtcaa
    59581 actagtctgg tatccagcat ggacgacaga taagatgagc cgttatgcac ggattgcgtt
    59641 ggggatacga tagaaatctt ggctgactag ctatgagaag caaataggaa aaacaaaaaa
    59701 gccttttatc ctttctagaa gaaaagagat aaaaggtttc tttgtttata aaattttgtc
    59761 tgctatatta taagttaatt aaataaatgt gttctattga taaaggacat tcaaatccct
    59821 ttccttttgg aatccttctt ttttacatca gtttgatttt cgtatagtat tctttctcat
    59881 cttcacgata aatcgcagcc ccattttttt gttgtgcttt aagactgcca agattttttt
    59941 tatttacaga caaaagtgcc tcatcaatgc cgattttttt tgcctcttgt agtactaatg
    60001 ctaatccttg tgtggcatat ccttttttac gataattagg ggagatgccg taaccaatat
    60061 ggccagcgcc gtttcttaat gtttcgttca gtttatggcg caaattaaaa attcctacat
    60121 actcatgttc atcactttct aaaataaaga cggttgcggg aacgtaactc tcaggaagat
    60181 cgattcctaa agacgttttt tcgcattttt ttacataatc taaaaattca gcaaatgtat
    60241 agccataagc attgttgata aatccactct catttggtcc aaagctagtt tgtagctgat
    60301 aagctttctt taaatctgct tcccatagtt tgatcagttt catcgtattc acctctttaa
    60361 gtaaccttat tcatttgttt tctactatag cactattgtt gtaaatagcc atgcctattt
    60421 ttatttattg tgtcatatcg tattaagaat catcgaacaa tacaaatatg aattacaata
    60481 aaaaaattat ttgaagttcg ttcattcgtt acttatgatc tctagaagaa agaaaacgtg
    60541 aattacttca gcgtctagaa ttccagaagg atagtaatca acagaagaaa taatcaatat
    60601 ccaaatgaaa gaagatagct gaatcgagaa aaagaggaaa aaagaaatga agaaaaaaat
    60661 aaaatagtta ctaatcccag agtcgttcgt ttaacattga aatcgatcat atggataaaa
    60721 cagatttttt caccaaccct caatagatga tggagttgct cggatgaatt atttgtgtag
    60781 atggcataag ggagggcgta cagaaatgaa aaagaacaaa aatatgttct tgacaaaaaa
    60841 cacatgtaat cctaaactaa aagatgtgat gcggctatgg cggaattggc agacgcgcta
    60901 gcttcaggcg ctagtgaggg tgacctcgtg gaagttcgag tcttcttagc cgcataattt
    60961 gtttttttat aaagagaagg tacacctgga gcgatgagaa agaaaataac atattatcta
    61021 aaagaatata ggaaaaattt taaacaacgg aaccagattc aaataaatca aaaaaaattt
    61081 gtgtgaaggt gggacagttt aaaacctaat agattgattc aaatagtaga tttatagatt
    61141 ctgatacaag aaatactggc aaacgatagt taaggaataa agactaaact taaactcaaa
    61201 aagaggtcat gcgaaagaat aaatcgcatg acctcttact atattttgaa tgtgtttaaa
    61261 cgttcaaata atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc
    61321 caagaaccat aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag
    61381 tagtcaccat ttaagtaaga agaatctaat tggtaacggc cgatgtaacg tccgttcgtt
    61441 gctgtgtaag aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtactt
    61501 gctggagtag cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct
    61561 gcttgtgttt ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg aacaggttca
    61621 gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct
    61681 tctgttggga ttgttaattg ttgtcctgag tagatcaggt taatatcaga aattgaattt
    61741 gattctgcaa tggcattgat caaggagtta tcaccaacgt atttttgaga aatcgttgat
    61801 agagtatcac ctgattgaac ggtataagct tcgtccgcat gagcagtcgt tcccatgaag
    61861 aatgcagcgc cggcagccaa agttgttcca aaaagtaaag ttttaagtga tgtcatgaaa
    61921 aatctccttt attcgttaaa aagttttatt tgttgtgttc aacgaggaat actttaacac
    61981 gtgaaaatat ttcataggta aaagaagcat gacaatttat gacaaatcca cgttttttgt
    62041 aacagaatga tgttcgctcg atgtgaaaaa tgatgaggaa tttcacataa tgcagaaata
    62101 atgggattag aacaggtgtt ctgatgagaa aagaaatgta taaataactt gaaagaaatt
    62161 gcttttgttc atcattttat ttacatattg cgtatatttt ttgtattttt gcttgagatg
    62221 ttacaataaa agaaaaagga ggcggttcca atgagtaaaa gataccagaa catcatggta
    62281 gcagttgacg gatcaagaca atcgatcaaa gcgttcgctg aagcccttga cttagcaaag
    62341 gacaatgaag cccacttatt tatcgtgtca atcatcaaca aagttgagct gacccatagt
    62401 gcctatgcct tttcaaaaat ctatgcagat gaaaaacaaa gaacagaagt agccatgctg
    62461 aaaaaaatca atgatgccaa agagtacggc attgctgaga tccacgcaat agttgaaact
    62521 ggagatccaa gaaatttgat tgccaatgtc atccctggac aagaaaatat tgatttgatc
    62581 gttatgggag cgacaggaaa aggtgctata caacaagcat tagttggatc gaccgcttct
    62641 tatgtcgtat cacatgcccc ttgcagtgtg ttggtcgtga agtaatgaga taagggagga
    62701 atagaaaatg gttcgtcctc aagaagtccg tgcgccaaaa gaaaaaatag aaattttagc
    62761 aattattgaa gacggcacac aaacaaagaa gggatactcg atcgctttag taaagtggaa
    62821 aggaaaaaaa ggtgttgctc tgagatggga tggagataac caacaagata aaggattccc
    62881 tgtcacagct aacggttatc atccagcgtg gtttgttctg cctgataaat ttatggaatt
    62941 atacagctat gattatgcaa gagccgcagc atcaatcaaa gcattagata aattaacaga
    63001 agagcagaat gaaatggagg aaaaataaaa aagacgaacc aatcagcctt tagaaaactg
    63061 attagttcga ggagtaaaaa tgaaaaaagg ttatttggga tgaaactaga ataatgcgta
    63121 taacttaaat aaaacttaaa gcaataaaat ggcaagaggg tgaggcaaat ggaagcagga
    63181 aaagtattac aggaagtaaa agcactatgt gcagataaaa aatatgaaga agcgaaaagc
    63241 ctgatcgaaa agaacaaaga aaatttggaa gaaaagtacc cgatcgcaca agaatttata
    63301 gaattaaaac aaggaacgat ccttcaccga ttcaaacatt tttttggtat aacagaatag
    63361 aaaaaacgat taaagatcgg cagaaatttg ctgcatcttt aatcgttttc tttttaaaca
    63421 tgcgagggat tcaattctga ttcttatata aaaaatagat ccaaataata agaaaaatta
    63481 ctgaaagcgt caattcgatg atgtgtgtta ttaatacaga cgttgtttcc caatgcctaa
    63541 aagaaaaaat ttgataagta aaatatacag caggtaaaga ggccagtaaa actgaaaact
    63601 tcttttttgt ccattttatg taatagaaaa gaatgcttat cataataaaa aaaggaatat
    63661 aaaaaacaaa ttgaccgatc gcgatcatac tattgcctcc gataaataaa gtccatgata
    63721 caaaataaca ctttgtgcga aatggcgcaa gcagttttgt ggatttatcc ggtaaaatct
    63781 gtatcgattt tgaaattaga ggagaaactt gctataatca aagtgaaaga aggagtggga
    63841 ttttcatgga tcatgtagtg ttagaaatcg atttgcattt gatcaataat attcgggtga
    63901 tttactatgt tgtaagtaac agtgtcgaac aacgtgtact gacgaataaa ataaatggta
    63961 ttttagcaaa gaaagacgtt caccgattca ataatggtga aggaagttat tatagtatcc
    64021 cagtagaaaa aattatttat acgacagtca aagtcagaga agatctagat accaaaaaag
    64081 catatgaacc tatttttaca acttattgat tgacagcaga tggaggaaaa aaatgaatcc
    64141 atatgaacaa cttattcaag atttgatcga tggaaaaatc gaaaagattg atgtaaaaag
    64201 agaagaatta atggcttttc gagaagcgtg gctgaagttg gagaatcgta aatatgtggt
    64261 gggaaaagcc tcactgaacg gcaatgtgac ttatcattac gatccgacac gtttatttta
    64321 gtatgaagta ttcagaaaag aaccaaagga ggacgatgca gcagcattgt cctcctttga
    64381 ttttacaaaa gtgaaagttt tacttatttg aatagatttt taaatttgtt tttgacactg
    64441 tcgatattta catcttttaa aagattttgg gctttctctt tataaggtcc taattgttct
    64501 ttatgttctt cgataaatcg ttttgcgcca tcgaaattgc cgttcttaat catttccttg
    64561 actttttgaa ataattcttc ttgattcatt ttgaacacat cctttgctat caacatgatt
    64621 ttttacatgg acaaaacgag aaaaactgat ttatccacac gtcaataata tcaaataacg
    64681 atcattttta ctaaaaaaac actcgattct cgcttctaaa gtaggagaaa aatctccaac
    64741 ttgggacgga tggaatttct ttaactgacc catatactga atatataaca aggaggtaga
    64801 aagatgaaag tgattaaata tttgattgga ctggcggcga ttagtggtat tttgctattt
    64861 ggactgaaat attatactga aggaagttat ggagaaatcc ctggtatact tgatcagcta
    64921 aatccattag ttgaaaaagg agaggtctat gtaaagacac aaaaaccaga ggaagtaaat
    64981 gaatatggta cagcaaggta tgtgcagaaa gctgctgatg ccaatgggaa agaacgaacg
    65041 gttgaattta atggtctttc tgtgttaaaa gaaaatcatt atttgaaaat tagcaataaa
    65101 ggagcacaca tagaaacgta tgaggaagtt cctagagaaa aagttccgga gaaagcatta
    65161 gcaattattg ggtaaatcag tttttgtatt aagaatacgc ccgattttat tattcataat
    65221 ttaattatgt aaactaaata caagtagtaa aaataataca ataatccccc tgcaaaaaga
    65281 ttgttctttt acagggggtt cattttttca gcaagcacat caaattggga tggcagggtt
    65341 cgaacctaca attgcttgat tcagagtcaa gtgccttacc agtttggcta catcccattt
    65401 attcaacaaa ataatcatag cactttccta aaaaaacgca agttattttt cttgatcgga
    65461 tagttgttgc tttactcgta aaaggcggcg tactagtttc ttttctaatc cagcaggaag
    65521 ggcaatcagt tctgctactg acaagacggt gtccaataac tgatattctt tgacaggttc
    65581 attcataata tgatagatgt ttgctaaacg ttcaatatat tcaaagcgag tatactctgt
    65641 tcgagcaatt agaaatttca ataaatcggt ggctttctcg tactcttgat ctgcgtaata
    65701 aacaagagat tgacgataca atttgatttc cagttcattg agggtagcag gtctgcgacg
    65761 ctcgttccac tcattaatag agactttacc ttgaacattt cccttgcagt cacggacaaa
    65821 aataatcgga atttcatttg gatccatttt tttatgtgtg aatttttcca ttatctacgc
    65881 tcccttcaaa ggtttggtat cttgagtata agggattttt gtttgaatta ctagcttttc
    65941 tccaaagtta gcatctgtcc acccattgca gtgaaaatcg ccgaaaaatc gttgatcggt
    66001 actgctcgat tttttacacc atagggatcg ttgacataaa tattttcttt gtcatatcca
    66061 gtgactacac aagcatgaac aagaggagtg actcttactt ctccattatt tgtggtccaa
    66121 gtcataaaat cagtttcatc tgggacttca aaattgatag tcacagaagt ccagacagga
    66181 tttcctttag atagtgcttt tttgatatca tcgagttgag catcggtttt tggaaaagtg
    66241 tgataatccg tttggacgat ttgctgagca agggaggcaa ctgggggaac atagacgacc
    66301 atagcccagt ctccgccact gatatcacca acaaatcctt cattaggatc gccatgagtc
    66361 ccatctgcat tgaaaacagg gacgtaatcc aattgctcag ctaactggtt tttagttgtt
    66421 tcataaccat aaaaagataa aagcatagaa agcgaagtga cttcacagcc attttctaaa
    66481 gaaggagaat caaactggct ctctaatgga acatctagta aaacttctgc tttctctttt
    66541 gtctttttcg ttttttgtgt tgaacttttt tgtgcagtgt tcattgtatg ttctggagaa
    66601 tggatatgta ggtaataact tgtaccgctt aataaaagag cagctgtgcc ccctagaaac
    66661 aatagttttt tgaacgtttt tttcttcatt tgaaatctcc cttttcagct gtttatcttt
    66721 cctattataa atgtattttt attggaaatg gaagtattat attttaatat gtaggaaata
    66781 attagttttt aagga
//
LOCUS       DADVXK010000005        64887 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.005, whole genome shotgun sequence.
ACCESSION   DADVXK010000005 DADVXK010000000
VERSION     DADVXK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.005"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1422)
                     /locus_tag="KB909_000290"
     CDS             complement(<1..1422)
                     /locus_tag="KB909_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6836353.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGN"
     gene            1674..2855
                     /locus_tag="KB909_000291"
     CDS             1674..2855
                     /locus_tag="KB909_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6836354.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2915..4543)
                     /gene="treC"
                     /locus_tag="KB909_000292"
     CDS             complement(2915..4543)
                     /gene="treC"
                     /locus_tag="KB909_000292"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBB6836355.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4994..7705)
                     /locus_tag="KB909_000293"
     CDS             complement(4994..7705)
                     /locus_tag="KB909_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836356.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7715..8416)
                     /locus_tag="KB909_000294"
     CDS             complement(7715..8416)
                     /locus_tag="KB909_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836357.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8602..9201
                     /locus_tag="KB909_000295"
     CDS             8602..9201
                     /locus_tag="KB909_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6836358.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9282..10295
                     /locus_tag="KB909_000296"
     CDS             9282..10295
                     /locus_tag="KB909_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6836359.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10403..11320
                     /gene="rbsK"
                     /locus_tag="KB909_000297"
     CDS             10403..11320
                     /gene="rbsK"
                     /locus_tag="KB909_000297"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBB6836360.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11348..11743
                     /gene="rbsD"
                     /locus_tag="KB909_000298"
     CDS             11348..11743
                     /gene="rbsD"
                     /locus_tag="KB909_000298"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBB6836361.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11743..13116
                     /locus_tag="KB909_000299"
     CDS             11743..13116
                     /locus_tag="KB909_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6836362.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13473..15617
                     /locus_tag="KB909_000300"
     CDS             13473..15617
                     /locus_tag="KB909_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6836363.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15669..16709)
                     /locus_tag="KB909_000301"
     CDS             complement(15669..16709)
                     /locus_tag="KB909_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6836364.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16986..18788)
                     /locus_tag="KB909_000302"
     CDS             complement(16986..18788)
                     /locus_tag="KB909_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836365.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18802..19554)
                     /locus_tag="KB909_000303"
     CDS             complement(18802..19554)
                     /locus_tag="KB909_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836366.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19563..19925)
                     /locus_tag="KB909_000304"
     CDS             complement(19563..19925)
                     /locus_tag="KB909_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6836367.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20101..20973)
                     /locus_tag="KB909_000305"
     CDS             complement(20101..20973)
                     /locus_tag="KB909_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6836368.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21024..21512)
                     /locus_tag="KB909_000306"
     CDS             complement(21024..21512)
                     /locus_tag="KB909_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6836369.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21650..22441)
                     /locus_tag="KB909_000307"
     CDS             complement(21650..22441)
                     /locus_tag="KB909_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBB6836370.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22496..23104)
                     /locus_tag="KB909_000308"
     CDS             complement(22496..23104)
                     /locus_tag="KB909_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBB6836371.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23097..23414)
                     /locus_tag="KB909_000309"
     CDS             complement(23097..23414)
                     /locus_tag="KB909_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6836372.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23570..24298)
                     /locus_tag="KB909_000310"
     CDS             complement(23570..24298)
                     /locus_tag="KB909_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBB6836373.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24457..25338
                     /locus_tag="KB909_000311"
     CDS             24457..25338
                     /locus_tag="KB909_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6836374.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25575..26618)
                     /locus_tag="KB909_000312"
     CDS             complement(25575..26618)
                     /locus_tag="KB909_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6836375.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26621..27289)
                     /locus_tag="KB909_000313"
     CDS             complement(26621..27289)
                     /locus_tag="KB909_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6836376.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27431..29767
                     /locus_tag="KB909_000314"
     CDS             27431..29767
                     /locus_tag="KB909_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6836377.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29882..30193)
                     /locus_tag="KB909_000315"
     CDS             complement(29882..30193)
                     /locus_tag="KB909_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836378.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30374..31849
                     /locus_tag="KB909_000316"
     CDS             30374..31849
                     /locus_tag="KB909_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBB6836379.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31896..32480
                     /locus_tag="KB909_000317"
     CDS             31896..32480
                     /locus_tag="KB909_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBB6836380.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32482..32865
                     /locus_tag="KB909_000318"
     CDS             32482..32865
                     /locus_tag="KB909_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBB6836381.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33182..33466)
                     /locus_tag="KB909_000319"
     CDS             complement(33182..33466)
                     /locus_tag="KB909_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBB6836382.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33818..34528)
                     /locus_tag="KB909_000320"
     CDS             complement(33818..34528)
                     /locus_tag="KB909_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBB6836383.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34525..35997)
                     /locus_tag="KB909_000321"
     CDS             complement(34525..35997)
                     /locus_tag="KB909_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6836384.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36135..36608
                     /locus_tag="KB909_000322"
     CDS             36135..36608
                     /locus_tag="KB909_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6836385.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36761..37312)
                     /locus_tag="KB909_000323"
     CDS             complement(36761..37312)
                     /locus_tag="KB909_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6836386.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37417..37947
                     /locus_tag="KB909_000324"
     CDS             37417..37947
                     /locus_tag="KB909_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBB6836387.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38430..38873)
                     /locus_tag="KB909_000325"
     CDS             complement(38430..38873)
                     /locus_tag="KB909_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836388.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38889..40049)
                     /locus_tag="KB909_000326"
     CDS             complement(38889..40049)
                     /locus_tag="KB909_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6836389.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40556..42256
                     /locus_tag="KB909_000327"
     CDS             40556..42256
                     /locus_tag="KB909_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836390.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42358..43191)
                     /locus_tag="KB909_000328"
     CDS             complement(42358..43191)
                     /locus_tag="KB909_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBB6836391.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43495..45660)
                     /locus_tag="KB909_000329"
     CDS             complement(43495..45660)
                     /locus_tag="KB909_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6836392.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45920..48214
                     /locus_tag="KB909_000330"
     CDS             45920..48214
                     /locus_tag="KB909_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6836393.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48207..48872
                     /gene="pgmB"
                     /locus_tag="KB909_000331"
     CDS             48207..48872
                     /gene="pgmB"
                     /locus_tag="KB909_000331"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6836394.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48865..49872
                     /locus_tag="KB909_000332"
     CDS             48865..49872
                     /locus_tag="KB909_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6836395.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49894..50913
                     /locus_tag="KB909_000333"
     CDS             49894..50913
                     /locus_tag="KB909_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6836396.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51194..52561)
                     /gene="nhaC"
                     /locus_tag="KB909_000334"
     CDS             complement(51194..52561)
                     /gene="nhaC"
                     /locus_tag="KB909_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6836397.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52670..54091)
                     /locus_tag="KB909_000335"
     CDS             complement(52670..54091)
                     /locus_tag="KB909_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6836398.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54334..56211)
                     /gene="tdc"
                     /locus_tag="KB909_000336"
     CDS             complement(54334..56211)
                     /gene="tdc"
                     /locus_tag="KB909_000336"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6836399.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56502..57758)
                     /locus_tag="KB909_000337"
     CDS             complement(56502..57758)
                     /locus_tag="KB909_000337"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBB6836400.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57870..58075)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58338..59639
                     /locus_tag="KB909_000338"
     CDS             58338..59639
                     /locus_tag="KB909_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6836401.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59708..60307)
                     /locus_tag="KB909_000339"
     CDS             complement(59708..60307)
                     /locus_tag="KB909_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6836402.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60561..61442
                     /locus_tag="KB909_000340"
     CDS             60561..61442
                     /locus_tag="KB909_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836403.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61455..63065
                     /locus_tag="KB909_000341"
     CDS             61455..63065
                     /locus_tag="KB909_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBB6836404.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63142..63801)
                     /locus_tag="KB909_000342"
     CDS             complement(63142..63801)
                     /locus_tag="KB909_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6836405.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64084..64749)
                     /locus_tag="KB909_000343"
     CDS             complement(64084..64749)
                     /locus_tag="KB909_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBB6836406.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        19458 a        13219 c        11704 g        20506 t
ORIGIN      
        1 atttcctgca tataaatgaa aatgttcgga gtcagccggt gcaatcgtgt gatcactgaa
       61 ttgaatatat ctaaaagcgc cactttcctt atcttctgct tcgaatagat accttacgcc
      121 acggtttcct gcctcgtagg tcaagatttc tttccctaca taacgataat ttgaacgttt
      181 cgttgttcca ttcttaaacg taaatgccat ctctttctca ctgatcttga ttgaagcaat
      241 atctgtttga tagcccttcg tataatattc tttatattct tgtgctgtct tatcctgatt
      301 caatttttct ttatattcaa aaacaggatc aaaagtccca tcttctacat acgtatctac
      361 tgtttgccaa gttcctgccc aatctgaaag agagcgatct tgtacatcct cgtcttcaaa
      421 ataaccgttg tagacgctct tttctttttt gggggtcaaa gtatcttcta gcgggttttc
      481 tgtctctgtc gtttttttca acgcttcgag gtttgcttcc atgatagaaa gatagttttc
      541 tccattttct atttgttcat tcgtcaatcc ttccaaagga ttcaatactt ctaaagatac
      601 acctgcttcg tttgctaacg ttctggcaat actatctttg gcgttttctt caaaataaat
      661 atagttgatt ccatgttctt taacaaagtg tttcagttca gcaattctcg ccgcagacgg
      721 ttcttcacta gaagaaagac cagcaatcga tacttgattc aatccatatt ctaacgctag
      781 atagttgaat gcagcatgtt gcgtgacaaa agatctttgt tttgcttgct taaaggtttc
      841 ttgataaagc tgatggagtg cttgaagttt ctcggtatag gctgctgcat tttttgtcca
      901 tacttcctgt ttttctgggt aagcttcaat cagctgatca cgtatgtttg ctacctgctt
      961 gattgctaaa cttggagcta gccatacatg tgggtctagc tcatgtgtat ggccttcttc
     1021 cccgtgttca tggtcatgat catgtccttc ttcacttccc ggaagtaaaa gcataccttc
     1081 tgtcgctttt atcgtatgga cattgccttc ttgtaatgtt ttttggattg cggggaccca
     1141 tgtttccatg ttttcatcat tataaacaaa gatatctgta tcttggatct ttgccatgtc
     1201 tttagcagaa ggttcataat cgtgggaatc agtccctgct ggaatcaata actctacttc
     1261 tccttcatcc ccgacgattg cttttgtaaa atcatacatg ggataaaagg tcgtcatcac
     1321 gctcaatttt tctttactgt cctcggcttt cccacttgcc ccgcaagcag ttaacatacc
     1381 tgctaaaacc agcatggcca atatacctat caatcgtttc atttatgaca ctcctcttct
     1441 catcttcttt catttgaatg ttccgattcg cttttcgcaa accgtaatag ttacgtttta
     1501 gcaacaggat ttaatttatc atatggttaa aagaactgtc aagcgttttc ttattttaat
     1561 tgatgagaaa gtttatatga atgattgacg atatttttgc aatcaacctc tatcattttc
     1621 cttttatacc cgcttttgtc tataatgaag ttatagataa aggaggaaaa agagtgaaaa
     1681 aagaaacaga tacaacgaat cgtttgatcc gctttttagg aggaaaaacc tcttactatg
     1741 ttttaggaat agttatctta cttgcgctga tcatttattt tttccatcag atctcgttta
     1801 tattcaagcc tgtcggaatc attatcgcta ctatcttgcc cccattattg tttgcactga
     1861 tcttgtatta tcttttggaa ccagtcatca aacgtttgag caagcacctt tcgaggaact
     1921 tgtcagtcat tatcgtttat gtgattattt tatttttatt ggggcttgga agcatatggc
     1981 ttattccttt tcttgaagaa caggcaaaga cattgatcag tagtttgcca gatttgtttc
     2041 aagattttca agagagtctc cgacaatttt tggagaaaac accttttgcc gattcattta
     2101 atcaattttt cgcttctatt gacgacgtga cgtctgatat agctggattt attggaaatt
     2161 attgggaaag tggcgcacaa cggatcagca acattttttc aactgttaca gctattttta
     2221 ttactttatt tactggtcca attgtcgctt ttttcctttt gagagatcct caaaaatttt
     2281 atcagtcagt tttagcgatt gtcccaccag catttcgtac agattttaaa aatttgacaa
     2341 agattgctaa tcaacaattg ggttcatttc taaaggggca aatcattgct tcatttatcc
     2401 ttggagcagt ctactgggtt tgtttcttac tgatcggatt agaatttgct agtgttttag
     2461 ctatttctgc tgggttgtta tgtatcattc catatattgg gccgtttatc gccttctttc
     2521 caggtttgat cattgcattc caagactcta cttttatggc tgtcaaattt gtcattgtct
     2581 ggtttgccgt acaacttctc cacggtgact tggtgattcc tcgagtaatg ggtgatcgtt
     2641 tacagatcca tccgattacg atcttaatcg ttttacttgt catgggtgat ctaatgggaa
     2701 ttgtgggcgt tatttttggt attcctatct atacgttagt caaattactc gttactttta
     2761 ttttccgtaa attcaaacaa cgctacaata aattttatgg cgataaagga gagtatgaaa
     2821 actcttcatt ttctgaagaa gattatttta aataaaacac aaaacgtcga tcttacgaga
     2881 atagctcgta ggaacgacgt tttgtgtttt tgttttaatt tttcagcaaa gcaattgcct
     2941 ggtatggttt tagctccaga ctttgatgaa gaacagtatc ggaataatta tcgataagaa
     3001 tattggcttc tgtgaatcct tctgggatgg cgatccttgt atctttatca tagaaatttg
     3061 ttaatacaag cagctgctgt ccttcaaatt ggcgaagaaa gccataaact tccggatgat
     3121 ttgcttcata agcatgataa tctccttgtg caacgattgg atatgttttt ctcagccgaa
     3181 tcaatttctt gtaataggac aaaatagaat cttcagaaga tagttctttt tctacattaa
     3241 tctcttctag cttgcctcca acttttaacc aaggtttccc tgtagtaaat cctgcttgtt
     3301 ctgtgtctga ccattgcatg ggtgttcgag agttatcgcg agattttgct ttgatccgac
     3361 gaaacgcttc tttttctgtg aatccttgtt caaggagtaa cttataagca ttcaaacttt
     3421 ctacgtcaat atagtcggaa atcgatgaat agtctgggtc gatcatgccg atttcttctc
     3481 ccatataaat atagggcgtc ccacggttca aatggatcat ggttgctagc atctctgctc
     3541 cttgttttcg atactgatcg atagctacaa atcgattgag cgcacgtggc tgatcatgat
     3601 tattaaaaaa tagagcattc cagccgttac cctcactcat cttttctccc catgtatgaa
     3661 atagtcgctt taattctgca aaatcaaatg gaggagtaga ccatttattc ccattttcat
     3721 aatcgacttt caaatgatgg aaattaaaga ccattgataa ttcttctcta ctaggttctg
     3781 tatacaagat acaattttcg atcgtcgtag agctcatttc accgactgtg atgatagtgg
     3841 aatccgtccc aaacgttgct tggttcaatt cttttagata cgtatgggtg attggtttgt
     3901 ccgtatattc aggtttgcca tcattttctt tattattttt caattgttcg tctttaccga
     3961 taacattgat aacatcgaaa cggaatcctt ttaccccttt ttccatccaa aaacgaacaa
     4021 ctttgaatag ttcctctctt actgcttggt tccgccagtt caagtcagct tgtgtccgat
     4081 catataagtg caaataatat ttccccgtat ctccaaatgg cgaccaagca cttccaccaa
     4141 attttgatac ccaatccgtt ggctcttctc ttaaaatgaa gaagtcctga taatgctggt
     4201 cccctgctag tgcttttttg aaccattcat gttctgtcga aacgtgattc agcaccatat
     4261 cgagcatgat ttctatccgg tatttctttg cttcggctat tagctgttcg aattcctcca
     4321 tcgtaccaaa gataggatcg atggctgtgt aatcagagat atcataaccg ttgtcttttt
     4381 gagggcttgg ataaataggg tttagccaaa tcatgtcgat gcctagatca ttcagatacg
     4441 ggagtttttc tttgattcct tttaaatctc caattccatc accattactg tctttgtaag
     4501 atttgggata gatttggtaa atgactttgt ctttaaatgt catggatatt tacctccatt
     4561 caactgattt attacctacc acaacttata tatacaagtt atcatttatt attataactg
     4621 aaccgaaagc gtttgtaaaa tttatcttta tacattctaa gaggtctgtt gcccaataaa
     4681 aaacaagaga tcagacatgt atttgtctat cctcttgttt aaaatagcaa aatattcttg
     4741 tttcttctat aaatggtgtt caaaagcttt tatctacggc aatcagtctt ctcaaatgta
     4801 aaacatgagg agctaatttt atttgagtat tctttttgct cgatgcagga cggctttttt
     4861 acaacctctg attcatggtg ttcaatcagc tgtccttcgg tattagctca aaaaacggca
     4921 aaatatgaaa aactattttg ccgtttgttt ctctaatact caggtcaaac cgctgatttc
     4981 acaacctctg tttttattca ttcgatttca acgcatcaat catatcgata tgctttaatt
     5041 tgaaatgggt aacaatcatc acaataaccg taaatacgat agttaatcct gctgataaga
     5101 cataagccca ccatgtgatc actaatggaa agatgacatt ctccatagac gcttgttgca
     5161 agatgaagtc agtcaatata tatcctacac caaatcctcc gatgattcct aaaagagtaa
     5221 agatgatatt ttctcgaaca atgtacatcg tgacttcttt atcaaaaaat ccaaggactt
     5281 ttattgtaga taattcgcgt acacgctcgg aaatattgat attagttaga ttatacaaga
     5341 cgataaaagc cagcagtcct gataatacga caaagattaa gacaaccgag tctaagttcg
     5401 ccattgattc ttcttgcgtt tcgatttgtt tggacatgaa agacgtattt gtcacagcgt
     5461 ctgtggcaag cagtttctcg gaaagcattt cttcttcttt tgttgtcatc ttatctgtac
     5521 gcagcaaaaa tgcattatcc atcatcgatt gatcagtaac tgaagcataa tattcagggg
     5581 acatataaat aaagctacct agatagtttt tcacgatttc ttttacttcg actttccatt
     5641 ctttttgatc ttcatcataa agcgaaatat gatctcctgt agataagtca aatagttctg
     5701 ctactttttg cgtaatagcg attcctgttt taggcaagga gcgtgggttc tcttcaagat
     5761 cagttaaatg gataaaacga tccaaatcag ctgttttact tggtacgatc actgtcagac
     5821 tttgcgaagc atgtcctttt tttctcaatt ctacggtttg agtatgaata gctaggatct
     5881 catttacttt ttcttgcttc tgcagcatat ccgctgcttt ttgacgacta tcttccgtgg
     5941 atgaatccaa tgtaacgatt gcttgatagt caatgatcgg tccaaattgt ttggctgaaa
     6001 cagaacttag agaatctttc aatcccacgc ctgcaaccat cagcccggca catccagcaa
     6061 ttccgataat cgccataagc attcttgact tatatcggaa gagatttcgg taactgattt
     6121 tttgattaaa gctaaggcgt gaccacagcg gagtgatgta ttcaagaaaa atgcgtttcc
     6181 ctggcttcgg tgctttcggt tgaagcaatg cagcaggccg ttctcttaaa tctttgaata
     6241 aaacgatcat tgcagcgcca aatgcggcaa tgaagaatgc ggcagctgct tgtaaaatcg
     6301 gcggccagtc ataaaaaata agcgcactcc caatatcata ccgctcgtta gacagctcaa
     6361 aaatgatcct tggcaaaaga ttcgttccta atatcgttcc taaaacaata cctatccctg
     6421 aggctagact tgcatagatt gcatattttt ttgcgatttc aactttcgta taacctaacg
     6481 cctttaatgt cccgatttcc ctgcggtttt cttctaccat acgtgtcatt gtcgtaaagg
     6541 tgatcaatgc ggcaataaag aaaaagaaaa caggaaaaac attggcaatc gcagcgatac
     6601 gatcagacag atcaccaaat tcttgaaaac cgacattttc tgaacgttca ttgtataggt
     6661 atgatggttt agttaaattt tcaatttttt ctgcatttcg attcaattct tcctctgcag
     6721 aggccagttc acgttctttc tcaactaatt gcctttcttg ttcagcaagt tgagcttctt
     6781 gttgagataa tgtttgaaca gcgattgttc gttgcgcttc aggaagctgc tggatagttg
     6841 ctgactgttg cgctaactgt tttttagcat cttctaaccg tgttcttgct tgcgttgttt
     6901 gtgctttgcc atccgctatt ttttgctgtg ccggttctaa ttcttcgttg gccgattttt
     6961 tcagctcttc taagcgttct tcgggtcgat cttgtaaata cttttctgcc ttttcttgat
     7021 tttgctccat tttatctttg taagctttgc tgtacgtatt caaattcttt acgtttgtaa
     7081 aatcaagata taagacagaa taaatatctg ttttaaaaac ggattcaggt aaatagacaa
     7141 aataatcgac gctaccattt ccgacgttcg cgtatcctct ctccaaattg ttgatgaaca
     7201 atggagaacg gacaaagccc gtgatggtat actctttttc tttcaattca tctgaatcaa
     7261 tctgataaat atcaccgatt ttataccctt catcttccgc tttttcatcc aatacaagct
     7321 ggtttggttt ttccgggagt tttccatcag ttaattgtag cttgttctgc ttgttatttt
     7381 tgttataaga aaatatttga atcacttcgt ttttgccagt attggaataa tagatctgtt
     7441 ttcctgtttc tacttttgca tctgggatct tttctgcttg agcaatatct ttttgtgtca
     7501 agccaccagt agaaacgatt tgcaaatcag aaagtcctgc tgtaccaaca tagtgatcca
     7561 tcgttttttg catgacaggt ccagcagttt tgacacctac aaataaaagt gttcctagca
     7621 tgacaataag gatgattgca atgaatcgtc ctttagattg ccgaatttcg cgaaaacctg
     7681 ctttaagata tgttcttgtt ttcataaaat ccccctacca tacaatctca tcaatggatg
     7741 aaggatgatc atttaattca acagacctta ctttagcatc attaatgtga atgactctat
     7801 cagcgatggg cgctaaagca gaattatgtg taatgatcaa aacggtattg ccgtgttgtc
     7861 tgctagcgtt ttgcaataat ttcaatactt gcttgcccgt ttcaaaatcc agcgcgcctg
     7921 tcggttcatc acataaaaga agtttgggat ttttagctag tgcacgagca attgaaaccc
     7981 tctgctgttc gcctcctgat aattgggacg gaaagttatt caatcgatga gctaggccca
     8041 cttgcctcaa tacctctaca ggatcaagcg catcaggaga aacttccgtt gccaattcca
     8101 cattttcttt tgctgttaga ttaggaacga gattgtagaa ttggaaaacg aaccctacat
     8161 ctgttcgtcg gtaagcagta agctgtttat ctgaaaattg cgcaatatct gtgtcatcaa
     8221 taatgatctg accttcatca ggtgtatcca tcccacctaa aatattaaga atcgttgact
     8281 ttcctgctcc acttggacca agtataatca ctaattcgcc tttttcaatt gaaaaagaaa
     8341 tatcgtcatt tgctgtaatg gtcgtttctc ccattttgta tcgtttgtat tcatttttta
     8401 cttcgacata cttcactctg attcctccat tttcacgata tttctcgcta tatctatgca
     8461 tcgaatgcgt tttctcacac ttatttattt taccactgaa tttctctaga ctaaagaaag
     8521 gaatccttta atttagttga caaataaacg atttatgatt tacttacata aaaaacattg
     8581 ttatttgaaa gaaggaacat catgaatgat ttaaaggaaa atatgatttt tgatttatca
     8641 aaaactgctt ttgtcgcgat cgacatgcaa aaagagatcg taaataacgg tacactctct
     8701 ccacacactg cagcatctat tctgacaaac aatgatttgt tagtaagaac attgaaacgt
     8761 accgctgcct tgaaagtttt agtgaacgta gacatctcca ctttccctta tttgagtcaa
     8821 caaactgata tgggtggaat gactgcttct gtacctccag aattcactga tttacttttg
     8881 aaggattctt tgaaagatac agataatatg ttgactatca caaaatacaa tccaagtgct
     8941 ttttttggta cttctcttga tcttcaactt cgccggcgtg gaatcgaaac tatcatttta
     9001 agcggtgtag cgacaacaaa cggtgtatat gctactgcat tagatgcctt tcaacacggg
     9061 taccatatcg tgcttgctga agatgcttgc agtgatcgtg acaaagaatc ccatcaattg
     9121 ttcataaaaa agatatttcc gaaaactgca cgagtacgct caacgaaaca aataatcgaa
     9181 gctatccaac aaagcaaata agtactggca cacgtgattt tcatttactt ctttttgatt
     9241 tcatgggaaa ataaccacag gatttagata ggagtatgaa catggtgaaa aaaaagatca
     9301 caatcaaaga agtcgctaaa ctttccggcg tttcaatcac aactgtctcc ttgatattaa
     9361 atggaaatac ggagaaattc agtccgaaaa ctgttcagaa agttttagct gccaaagaag
     9421 aattaggcta tcagcctgac tattttgcta gacaaatgat taccaaggaa acgaaaacaa
     9481 ttggtgtact cgttcctgat atcacgaatc cattcttcag tacactgatg cgaggaattg
     9541 aggatatctt gtataagcag aatttcgtca cgatattatg taatgctgat tctgatcatc
     9601 aaaaagaaat cgaatatcta gccgagctca cacgtcgagg tgtggatgga ttcattatcg
     9661 cgacttctgc tgtctctaca gatgcaatca acgaaaattt gaaaaaacaa ggccggccct
     9721 tcattgtttt ggatcagaaa aaatctgaag gatttagtga tgccgtacga acagacgatt
     9781 ttcgcggtgg ttacctagcg ggcatgcact tgcttagtct aggacatcaa acgatcgccc
     9841 ttgtctatcc tgaaaatcca ccggaaaatg tccacgctcg gattgagggg tttaaatctg
     9901 ctcttgatgt ttaccaaatc cctcacgacc aactgatcct cttacctaca cagttctcaa
     9961 aacaaggtgg ctaccagatc acagcagaac ttcttgattc tgctgcaact ggtgtgtttg
    10021 ctttaaatga tgaattagct tttggattat atcgcggatt agaggaagct ggaaaaagca
    10081 tccctgaaga ctacagcatt attggctatg ataatataga tatgtgcgag tatatcaagc
    10141 cgaaactgac aacgatcgca caaccaatct tcgaattggg acaaacatct gccaagttat
    10201 tgttagatcg gatccaattc ccagaaaaag aatgggaaga aaaaagatta cctgtacgat
    10261 tagaaaaaag attttcaact gcacccttga aatagctttc aaggtgtgct atatttttat
    10321 cgaactatta aaacgtttta ctaaaacgtt ttaaaaaata attttcccat caaaataaat
    10381 gagatagttg gaggtttgta aaatgaacac ggttacagta attggaagta ttaatatgga
    10441 cactaccctt cgtttaacca acatgcccaa gccaggcgaa acgatgcatg cgcatgagat
    10501 ttttcacgct ggcggaggta aaggtgccaa ccaagcagtg gcagccaaac gttcaggcgc
    10561 acggacatct tttattggag gcgttggggc tgacagcgaa ggacaacagt tattagatct
    10621 actgacaaaa gaaaacatcg atacatctgg gatagctgaa atccaaggcg ccacaaccgg
    10681 acaagcaatg attatggtag acgcagcagg agaaaatagt atcttgatcc atgcaggggc
    10741 aaataatgct ttccatgaac aagaagtcct aaaaaacaag caactgatta caaacagtga
    10801 ctttattatt gctcagtttg aaagtagctt agatgcgacg atcctagctt tttctattgc
    10861 aaaagacgca ggaaaaacaa cgatcctgaa tcctgcacca gctcgtgaaa cgattcctac
    10921 tgaactactt gaaaagacag atatcattat accaaatgaa acagaaacag aaatcattac
    10981 aggaatcaga gtgacagatc ataacagttt ggtcgcagca gccgaaaaac tccatgaatt
    11041 aggtattgga acagtaatca ttacactagg cagtgccggc gctttctatc atacagaaaa
    11101 agaacacggt atcgtccctg cttttaaagt ggatgccgtt gacacaacag ccgcaggtga
    11161 tacatttatt ggcgcattaa gcagcacact tcagccagac cttagtaact tgaaagaagc
    11221 gatcctttat ggaaatctag cctcttctgt tgctgtgcag tcttatggtg cgcaaccttc
    11281 tatcccttac cgcgaagctt tagaacaatc agcagtctaa aattaacaat gagaggaaga
    11341 aacaaacatg aaaaaaggaa aagtaatcaa ttcagatatt tcacgagtaa tcgcacaaat
    11401 ggggcacttt gataaattaa gtatcgggga tgcaggcatg cctgtcccct ttggtactga
    11461 aaaaatagat ttggctgtct caaacggtct tccaagtttt ttatctgttt tagaaaacgt
    11521 tttagaagaa cttgaggtac aatcgattga attggcggaa gaaataaaga caatgaaccc
    11581 ggaaatattg gaaaaaatca aattattgtt accagataca ccgattagct ttatcccaca
    11641 tgaagaaatg aaaaaagagt tgaataactg tcatgcattt attcgtacag gcgaaatgac
    11701 accttacgcc aatattatat tagtgagtgg agtggtcttc taatggaaac gacaatgaat
    11761 cctgaacaga tggtactgtc cgagcagatt catatgctga ttgaacagtt gggaggaaaa
    11821 gacaatattg attctgtcct tccatgtgcg actcggcttc gtatcaaatt gaaaaaacag
    11881 ccagtagcca atgcagaaaa attaaaacag caaatccctt ccattaagta tttcatttta
    11941 ctcgatagat atgcagaaat aatcatggat cagggattgg ctcctgctta caaggaattg
    12001 acgcgtcaaa tcgatcattc agctccgaaa gaaaagctaa atccgatcga aaaactattt
    12061 ggtttgatat cggaaatctt tacgccgatc attccgctgt ttgccggttc tggtatatta
    12121 aaaggtctgg ttgttttagc gactacgatt ggctggctta gtgaaacaag cggaacttat
    12181 catattttgt ctgctgcgtc gaatgccgtc ttttattttc tgccaatctt tcttgctttt
    12241 tctgctgcca aaacgtttaa agtgaatgga tatattgcgg ctgtcattgc tgcagcactg
    12301 attgaaccga atctgacctc tttactttca gacagtggca aagcagctac tgattttctg
    12361 gggattcctg tagtactgat gcagtatacg tctactgtca tgccggcgat tttaggtatt
    12421 ttcttttatt cttttgttga aaaattcctc aaaaaatata ttcgcgaaaa tatgcaatta
    12481 gtatttgtac ctttactttc attagttatc acggttcctt tgacgttaat ggtattcggg
    12541 cctgcgggtg tttaccttgg cgaaggttta gctgccgcaa ttacttggat gatggatatt
    12601 aacggaccga tcagtggcgc aatcatcgct ggtggttgga atattttggt aatatttggt
    12661 atccaatggg ctgtaaaccc tgtcatgatc agtaatatct ctgcttatgg gttcgaccga
    12721 atcgttccgt tgacaggagc agccaatttt ggaatggctg gtgcagcttt aggtgtattt
    12781 ctgcgaagta aacgttcaaa aacccgttcg atctccggtt ctgcttttgc ttcgatttta
    12841 cttgcgggag tgaccgaacc aactgtttac ggaattgcga tcccattgaa aaaaccattt
    12901 gttgctgctt gcattggtgc agctgctggt ggagctgtaa tgggatttgc ccaagtgaaa
    12961 gcgatcgctt ttgtatttgg tagtctgacc acattgcctg cattcatttc cggtactttt
    13021 ttctggtact tagcaggact ggctgttagt ctagtcgtag caatgatcac tactctcgtt
    13081 agcgggtttg atgaagacct aatgtcttat gaatagttaa tgaaaaagac tgaagtatga
    13141 gatgtttatc acatatttca gtctttttct ttttaggatc attattttta taaatttttg
    13201 tgatactttc caaactttgg tataatttac atatgcataa ccatttttat ccccacttgt
    13261 ttatccccaa acaaaggtgg tctatgcaat aaaatgaacg tcaaagaaaa acgaatgaat
    13321 gctcgttgct tatttacaaa ttgttttatt tagaatacac agacagattt atgaaaagaa
    13381 aaagcttttc gacacgatta tctgttccaa aaaatgtcta atgaatgctg aataagacag
    13441 aaaatcaatg aaaggaaaag gactagttta ttatgaaaaa taaaaaaacg atacgtttgc
    13501 tagctgctac ttggctgatt gctccgtctg ttttgtcgac caataccgta tttgccgtag
    13561 ataatcaaat agctgatcaa acagtcacaa cagatacgac tacatccagc tcagctacta
    13621 gtgaaacaac ggattctttt acagaagacc caactggaac aactaactca acaacaggat
    13681 cgaccgagcc aactgaaatt gatccggctg atccatcaga aaatgaaaag ccagccgaga
    13741 catattccct tacaattgct ccttctttga ttggtaagat ccaactgact gcttcgacag
    13801 cggattcccc tgaacagcaa cctttggata ttacggaaag tggaacggta gaaggtttat
    13861 tagcggaaac gaaggtaact tacactatta cgccagctga aggtgaacaa attgcttcag
    13921 tcgctgttaa tggtgccaaa gaagtaaatt atgatgcaaa gacctttaca gtaggtacga
    13981 acaatttatc tattactgca gaatttaaag ctggaccgga tacttcaaca gagaaaccaa
    14041 ctgatcctag tgaagaagtc cctagtacac cagatccgga aacgccaaac aaaccagatg
    14101 tgggtaataa caacaataat aatggttcaa ataattcaaa caataataac aataattcga
    14161 acagcgggaa ttcttcgaat caaacaaacc catctggatc gaataacaat ggaaatactc
    14221 agagagaacc aaaccatcca aacaatggtt catcgaatgg cggaacgaac aatgcttcat
    14281 ctcgtccaaa tacagcaaat caaagcggta tagagaatcc atcttctgct tcttctgatt
    14341 ttgttgtaaa atcaccaatt gatgctgtat tgcctacaaa tacaacgaat gtccaacaag
    14401 caatcgttcg agaagcattc aagcatcttg gaaaaccata tgtatgggga gcaaaaggtc
    14461 caaatacttt tgactgttct ggtttgactt attacgtata tatgaaagca accggtcatt
    14521 atatcggtgg ctggacaggc gaacagcaat atgcaggtac gcagattcca gtaagtcagg
    14581 cccaacctgg cgacctcgtc ttctggggac cttcttccgg tgttactcac catgtaggta
    14641 tctatattgg gaacggacaa tttatccatg cgcctcaacc aggagataaa gttcgagtaa
    14701 cttctatttc agatttcacg cctgattttg ctgtccgagt aaacttagca ggtttacctg
    14761 ctgcttcagg ttcgctgaca ggcggctcat ctattttaga tggattagat ggctcgttcc
    14821 atttcagtca aaaccaaaca actgatcagt tcttgaaaaa gattgcagat gatgcacagg
    14881 aaatcgggca aaaagaagga atctacgcat cagtcatgat ggctcaagct atccttgaaa
    14941 gtggatctgg aaacagctta ttatcaagcg aaccaaatca taaccttttt ggtatcaaag
    15001 gatcatataa aggaagcagc gtgaccttca atacacttga acaagatagt tccggacaaa
    15061 gctaccaaat ccgcgcacaa ttccgtaaat atccttctta caaggaaagt ttggaagact
    15121 atgccgactt gatcaaaaat ggactgactg gcaatcctga tttctacaaa ccaacttgga
    15181 agtcggaaac aaaagactac aaagaagcaa ccaaatattt ggaaggacgt tatgctacag
    15241 atcgccaata ttcacaaaaa ttgaacgcga tcatcgaagc gtacgacctg acaaaatatg
    15301 atgaaccgaa aaaagaagca gcaacaactg aagaagcaaa cgctgaaatc ctcaatatgt
    15361 ctaagcgatt cgatgtgcca atcaaatgga caacagatgg cgtgccaatc acaggattag
    15421 aattttcaac gataaaacgc gtcaacaacg cttcttccat cttccgtgtc gcttcaatct
    15481 gggatttgtg gaacaatttt acggcaagac agataccaga aacaactact cgtacagtta
    15541 aagctgcaac tgttcctgta ctaaccttgt taaggttaga caaatcattc tggcttgatc
    15601 tgcctttaaa gaaatagaat aaattaaaaa ggggatgtga cactgtcaca ctcccttttt
    15661 aatttattct atttctttat atttattttg tattccgtta caaactcgcg tacttggtta
    15721 ggttccagag tgacatctcc aaaactttca agtcgctccg ctcctggcag ttcttgagtc
    15781 tcaaatgtga taccgccatg atttactaat ttattcccgc gcatttccgg tccatcttct
    15841 ccaaaatttg ctgtaaaaat cacgattcct gaagcatctg tttttacttg gatcgatact
    15901 ttttcatctg ggcttgtcaa ttccgcagca tttagtaaac cagattgttt tttcaacaaa
    15961 aatggatgat cgatgccgcc cactatcatt gattggcgaa aatcactggc aaagacctca
    16021 cctaattttt taggacgttg gaagtcaaat gctgtgccac ttactgaaac tacttctcct
    16081 gtaggcgttg tatctttatt gagcgtagca aataatcggc tattcaacca aagtatatgt
    16141 tcgtcgattg actgtgctgg atcaccggtt aaattgaaat agacatgatt tgtaggattg
    16201 aatactgttt tgcggtcact gatcccttgg accgtcactc gccatgtatc atcgttcgtc
    16261 agcgtatacc gtacttctac atctaaagtt ccaggaaatc cgttttccat atctgggcta
    16321 gtctgataga aaatgaccga tgcttcgttt tcaccattga tgactgtata atgccactgc
    16381 ttggcttcaa agctaggtgc accaccatgt aaacaatgac cagtgtccgg gtctgttttt
    16441 acttcgaacg tttcatcatc taatttgaat gtgccattcg taatccgtcc agccatacgt
    16501 ccgattgaag caccgatata agggtctttt tctagatatt cttttgcttc atcaaaacct
    16561 aagatcaact ctcgtttttc attatcgatt attgtttgaa aatgaacaac ccgtgcccca
    16621 agatcactga cagacaaaga tgtcccattt tgattcgtga tcgtaatcaa gtgatagttt
    16681 tcgccaaaat tttgttcatt gatttccatg ttccttgcac cctcttttct ttcatttgca
    16741 ctgattccag tatacatgga aaccgttttc ttaacagctt attccgtgag taacgagaaa
    16801 aaatttacta tattctaata aaagaccgtg aaaaaaaggt tgtgacaaaa atattgtcac
    16861 aacctctttt tccgaacaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc
    16921 aaacgaaaaa tatgaggagc tatttttgct tggctgttct tattacttga tgcaggacag
    16981 ctttttcaca atctcttttt caatacgatt ccagtatata accatgtcgt cagtacatag
    17041 tagatgaaat acaatacgaa gaatatcgta aacggaaccc aaatatcttt gtatggattt
    17101 tgcatgaata gaccaaacat ttgtaatccg aataagacat ggactacacc taagattcct
    17161 ggtgctaaga ataacacgcc tacttctcta cggatcgatt gtttaagcaa cccgcgtcgt
    17221 gttcctatct tttcaagcat ttcataacga gcaatgtcac tcttgcttcc tgacaagatc
    17281 ttgaacatca aacagctagc aagcatggtc aagaaagcta aacctaggaa gaatcccata
    17341 aattcaaaac cagagaatag accattatac acttcataca tttcatattt ctggttgctg
    17401 tactctactt tttgcaaaga tggattgttc attttatttt gagcaacaag tgtttcgatt
    17461 ggtttcaggt ttgcttggaa gtcttttacc tgaactagct gtaaagtgga ttgtggcaag
    17521 ttcagttgat caaattctga ttgactgact accttgattt ctttttcttg ctgttccggc
    17581 aattcatagc ttcgaagttc ctcttgtaca gtcagttcat tcattttttt agcaggaact
    17641 ttttctttcg tgatcttcgg cggtgttcca tcttcatgtt ttatcatgat caatggttga
    17701 gccgcaaatt cacttgcatt atagtaaatc gttcccgcat cttctttttg agtataagaa
    17761 gcagaaagtg ttggtgaaag ttctttgatt ttttgctgat cttctgcccg aggattattc
    17821 atcactagat catatccaga attgttttct gtcaagtctg caatttcatt tttaaaacct
    17881 aatcctaccg tcaaagcgcc cagtgccaag gcaaacagca tagcgaccat tgagagcatt
    17941 tgtgtatatt cacgaatacg aaagtttaac tgtgacaatg tgaaattgtt caattttttc
    18001 aatgaaatct gttctgattt ctttagtaat gataaaaaga aaatgatcac agaatggaaa
    18061 atgaaataag ttcctaatac gatcgtaact aaggctaccc ctataccaaa gacttgatag
    18121 gtccccacgt gtttcatcat atagtaaccg cagcctagaa aagcaattcc cagtactact
    18181 tcaaggaaaa acaagaattt atgctgcttg attcttgttg gtgtctgatc cgcacgaatc
    18241 aatgctaaaa tcggtttttt gacaatcgaa aaagcattga caacagcagc taataaaaac
    18301 aaaacagcaa aaaacaaaac agtgatcaac aacccgtgaa tactaaaagg tgtaaaatgc
    18361 gaaatattga gatctaactg atccactaat aatcggtgga cgatacttgt caatcctaca
    18421 ccgacagctg aacccactaa agtagctgcg atccctacta agaatgtttc agaaaaaatc
    18481 atctgtgcga tttttctgcc ttttgctccc agcatcataa acattgcata gtctttttgc
    18541 cgcatcgtca tcaaaaagga atttgcatat aaaatataaa cgaatgtgat gatccctagt
    18601 aaaacagaac cgaatcggaa aatgataact gtagccgcaa cgatcgtatt acttttcaaa
    18661 aaagcttcgt tgcttgccat tgattcaaac atgtaaaaaa tagcagatgc cataactaat
    18721 cctgagaata acaccaagta gtctcttaaa cggctcttga tcccagtaag tgataatttc
    18781 caaagcatag tcaatctccc cctactgttc caagtttcca agaatagata gtatttctcg
    18841 atagaaggaa tcacggcttt gatctccacg tttcacttct tgatggatac cgccatcctt
    18901 gatgaataaa atacgttggc aataacttgc agaaaacgga tcatgcgtca caagaagaat
    18961 cgatacatga tcttttgtat tcaattcgtc catcgtatct aaaagatccc gggcactttt
    19021 ggaatccagc gcacctgtag gctcatcccc taatagaatc gttggttgtg tgatcaatgc
    19081 acgtgcggcg gcgacccgtt gtttttgtcc accggaaatc tcagaaggat agctttccaa
    19141 aatatgagag atggataaac gttctgcaat tttttggaca cgttgcttga tttcttttgg
    19201 tctgacgcct tgtaaagaaa gaggaacagc gatattttct tgtgctgtca agctttctaa
    19261 taaattgaaa tcttggaaaa taaagccaat ctcattcgca cgaaaatctg ctagttgatt
    19321 tccttttaat gtggtcacat ctttttgatt gattcggata tgcccatctg ttggtttatc
    19381 taatgtggat aaaatattca aaagtgtcga cttaccagaa ccagaagcgc ccatgatccc
    19441 aataaattcg cctttttcta catcgaagct gatgccgctt aatgcttgcg tctttttctc
    19501 attgtttttt ccgtatactt ttgttacatt ctgtacttcg actattttgt tcatttcttt
    19561 ccctaccctt taattagttt ttccagtgct gttttcggca cgtctttttt ttcgacttct
    19621 tcatacgaag tgacaccttt atttttgttc caggtgattt ttaaatatgc tcctttacga
    19681 agcggtcgag tcaattgtcc cttgaagtcc agttcttttt ccttaccctc tttcgtatag
    19741 ccaggcagga tatatctata gttgactgtt tcttgtccag agtctgattt tgaaactgtt
    19801 tttgtaccat ctgtcgtaat ttgtacatag tattcttctc cacccataac tacgtaatct
    19861 gcgattttca cccctgcaag taccacaacg atgaaaacaa gtagaccgat cagaagtttt
    19921 ttcacttttt ccccttctct cttactttat atactgatta tagaaaaaag cgaacaattc
    19981 tgccttcgaa tcaactatca ttcttctttc aattttgtca ttttctttaa aacaactaaa
    20041 aaaagagttc aagacaataa tccgtcctaa actccttctt cctatcttac aaaaagtatg
    20101 tcacttacgg tctttcatgt cgcctgtatt gataacaggt tgcgttcctt tgtctgtaat
    20161 gattgagaca agtaaattat tgatcaattg gactttccga tcatcggtga aattgatttc
    20221 ttgtccatct tcgatttgct ctaaggccat ttgagtgatt gtgacagctc cttcaacaat
    20281 ggtttgtcga gcagacaaaa tggcttttgc ttgttgacgt tggagcatgg cactagcgat
    20341 ttctgttgca taggctaaat ggttcaagcg tgtttcgatt acttcgacac ctgctactgc
    20401 taaacgctct tgcagctctt tttgcaactc gtcagacact gccgtcgtgt ttcctcgaag
    20461 cgtcaaatca ttctcattga atgtatcata cgggtattgg ctagcgatat gccgaatggc
    20521 tgtctcactt tggatttcta caaaatcttg ataatacgct acatcgaata atgcctttgc
    20581 tgtatcaacg actttaaaga ctactactgc tgagatttcg atggggtttc catccaaatc
    20641 attgactttt aaaacagaac tattgaaatt ccgaactttc aacgaaacag tcattttttg
    20701 tgccaaaggt atcgtaagga aaaagccatt ttctcgaatc gtacctaaat attgtccaaa
    20761 aaacaaaatt acttttgctt gattaggact gactacagtt gccgaactta acaacaataa
    20821 cgtgatcaac caaagaaaaa tacttaaaaa aagtgcccaa actttcgctt gccacatacc
    20881 taaatagaag aaaaacaatc caactaaagc taatacgacc aatccgacaa tccctgcata
    20941 accattgata taaaatgctc ttttttctct catgctactt cctgcgctcc tttatccttc
    21001 aataaatatc taatgttact tttttaattt ttttttcgaa tacgcgccat tacaccttct
    21061 agttctaact ctttgtcttc agtgatgtac caaccgcttg cctgtgtccc tccggctgcc
    21121 tgcggtaaat aatccaattt tgttcgaacc cagtgctttt cttctgtaaa atagtcttct
    21181 accaagacct ctagatccat ccctgctgaa agaggcaaat cttcccgaac agatttaaag
    21241 ataaatcgtt ccttcttccc atcatacttc aatattcctg tatcgataat cggtaaagaa
    21301 taataatcca gctctttctt caccgtcaat aaatgtttga aaacttcatg gtacacttgc
    21361 tctaattggc gaccttctga attgttcggg taattaacca tcactttttc tttgtctgga
    21421 tcatagaagg tttggcttag ttgagtgata taagtatgta atctttccat ttctgttttt
    21481 aacttttctc tttgaccttc ttctaccttc atatactctt tcaccctgtt ttctttttag
    21541 atattttctt tcttatttta ctatagttat gtgcgttaag cgatgaaaaa cagcaaagat
    21601 tggaaggatc tttgctgttt tttcttaaaa tatccagttg agtacaggat caatctgttt
    21661 cattgtcctc ttgatccgtc gtaatattga tcgatgtgtc tttagcagtg atctttagct
    21721 ttttctgtcc ttgttctaac aaagtatttg ttattggctg gtagtctttt tcaatataag
    21781 attcaccaga cgtttggata gtatagccac tgttttccat ctcatgcaaa gataaattgc
    21841 caccgtttag gatgactttt ccttctttgc tgatcaaact gtcttctaga tggaagttgc
    21901 tgttttcacc tgtgacgatc aagttatcca cattggcctc atctaatcga agtgagccta
    21961 attcatcttt cgcagttatt gttcctcctg taaattcatt gaacgatacc cagccatcat
    22021 gtgtcttagt attcactttt ttgattgata cttcgttgat atcaattgca ctattattcc
    22081 cttcgattgt caattcagat aattcatgat ctgcagggac aacaatagtg atttgtgcac
    22141 ttgtgtcttc taaactaatg attgcacctg ttgatttttt gactgcattc acagtcaaca
    22201 cgccattttt ctcctttatt tctggctttt ctgtcttatc ataagtcgtt tttatctcaa
    22261 aatccaatcc gcgtatgacc gaaactgttt gattttctgc atggatgacg attttgtttg
    22321 catccttgat tttttttgtc tcagtaacca tatcgatcaa ccgaggacca ttatcccaag
    22381 tcagactctt ttgagcgcct aatgtataag ttgcacctgc taggaggcca ccagtaagca
    22441 tcagaccaat accggtaatc aaaaaatgtt tcaatctcaa tttatgtgtc ctccttcaaa
    22501 cgcccgctga atgcagatct ctttttgtaa taaaacgtcg tcccatccat ttaacaaagt
    22561 tcatcatgac ataaaaaagc ccttttgttc ctttcagcaa cagtggcgaa ataaatactg
    22621 cgcttcctgt ggcgaacaga ccgacaccga taaagaataa tccactcaga atcgattgtc
    22681 caaacacact gattcctgag atgatcatga ataggccaac acctaagata ctgatacata
    22741 aaacatagat actaaaaatg agcgctagta aagcaaccaa tagtccccca ataaccaata
    22801 taaaccccag tgctagtgga atgaggacag gagaagcaaa taaaccgata atgattaacc
    22861 aaatcaggcg aatttgtctt tttggatttt tcactaactc gttttctgct tgttcttctt
    22921 ctgaaaagta actgattttt aattttaagg caaactgctt tggtgtacca tattcatcaa
    22981 tgatctgatc taatgttttt ccagaatcta aaaaatattc ctcataatac tggatcaaat
    23041 caaaacgatc gtcttcagga atttcttgaa gatgatccac aacttcattc aaatattcat
    23101 tcatttgtgc tctcctccaa taaccggtct aaagaatctc gaaaaacaat ccattcatca
    23161 ataatttctt ctaaatgacg acttcccatt ggtgtcaacg agtaatatcg acggtttctg
    23221 ccttcaaaag gttcatcata ggtctcaaga tatccttctt ttttcaatct tctcaaaacc
    23281 ggatatagtg tagattcact gacagagaga ctttcttgta cgatttttgt taaggcatac
    23341 ccatacatat cttccttgct taatgctgct agcacagtac catcaagaag aacagttgga
    23401 atctggatgt gcattacgtc accttctatt ctcaagtgta atattttatt tcaatctata
    23461 ttatacaaca tataatatag tttcaaaatc agtttgtcaa atacaaaaaa actgactaaa
    23521 agatttgatc ctttttagtc agcaaaaaat ggcttctctt tgatttttat tataacagtg
    23581 gcataatcca atttgtccac atccagctca gtggcatgat aacgatcatt gcaggtatca
    23641 tgtcagctac tgggaacatt ttcacgttga tcattctaaa accggtagcg accatcaaga
    23701 atccgccgca agctttaaaa tctaagatca tgtctggtgt agtcaatgga taaataaatt
    23761 ttgccaataa gaacaaaata taaaaaataa tgaattgggg aattgctatc acagaaacga
    23821 cataccctaa attacacgca aaaatagctg ctgtgaaaaa atcaaggaca gatttagaaa
    23881 tcaaaatcgt actgtctcct gtcatcccag aatctaaact tccatagatc cccgtaccac
    23941 ttgcacaaaa tagaacaatg accgtcacta atgtgctgat aaattcatcg tgggtcatac
    24001 caagcttttc actagggaag attttagaaa taggtacttg catcagcgca gcccccttat
    24061 ttatcccatt acctaaatga acaatcaaac caatcgctgt tcctatcact aaagcaaaaa
    24121 taacagccgg catatttttc atcggcgcaa tggaatagat tcccatcccc atcgaacaca
    24181 caccaaaaac catcgtcagc tgtgctttaa aatgttcact taatttattt cctactaatc
    24241 cgccaattag tccgccaaac aaaacggaac ctacattgat caaaactcca gttggcatca
    24301 aaaaactcct ctctttttct acgaagcgaa aaaaatcaga aaaatttctg taattattgc
    24361 tttcgctgca agaaagattg taacagacag agaagattac accaattcat tttttgtgtt
    24421 aaagtattct ttattggaat aagtaggagg aatatgatgg atatccataa attcgaagtt
    24481 tttcttgatt tagccgaaac aatgaatttc accaaaactg ctgatcgaca attcaccacc
    24541 caaggaaata tttctaaaca gattctttcg ttagaaacag aattagacgt caaattattc
    24601 gaacgcgccc atagaaaaat cgaattgacc gaagctggaa gcttattgct cccatatgta
    24661 aaaaatgtcg tagaacaata ccatgctatg caagaagtgc ttgaaaccta tacgaaagac
    24721 aacaatcttt cattaaatat cttaacgata ccgacaatga tcaattataa aggtttttcc
    24781 aaaatcaccg agtttttgaa acgccatcct gaatttacag tccagttgaa agaagtggaa
    24841 agtgtcgaat taacttacaa tgacgccaat gaacatagtg acacgatcca ctttgctaga
    24901 agtttccagg ccccaccaag ttcgattgag tggttgccta ctgaaacaga cgattttgta
    24961 gcagttctac ctaaaaatca tcctttagct agtaaaaaga aattggatct aagcgaactg
    25021 aaaaaggaga actttttgct ccttggcccc actacgaact tgtatcaacc tgtactagat
    25081 ctgtgtcgcg aagctggatt tgaaccaaaa atctcttata aaggagcaag aatcgacttg
    25141 atcatcaata tgattgcaaa tgacatgggg attgctattg ttatggaaaa aacagtcaag
    25201 aatctattaa aagaaaatac tgtgattctc cctatttctc caacaacaga gagttatctt
    25261 gcatttactc gtaaagtcgg tgagcattct ttggcttcag atacattttg ggagtattta
    25321 aatcaagaag aaaactaagc cctacatttt ctgtccatct atccacccaa aaaaagagag
    25381 cgacgcatga ctttcgctct ctttcttgca tcatgtcctt gtttcaatga cacctctaac
    25441 atttctcgta gttcaataag aaagcagcga tttttatgcc aaaagaaccg taagaacatt
    25501 tccctaatca caaaaaaacg actaaaaacc cctaaaaacc ttcaatagaa tttttagggg
    25561 ttttattctt tttcctattg tttacttaac cgtatcattg ctgtcgttcc tactccttcg
    25621 atactgctat aatcaatacg tccatcatgc agttctagaa tttttttaac cagtgaaagt
    25681 cctagcccat tcccagaaat ttgacgactt gtatctcctt gataaaattt ttcaaacatt
    25741 cgatctctgg tctcttcatt cattcctaca cctgaatcgg tcacttccag tacaatctct
    25801 gtggctgtct caaatagttt gatatgaatc tgtccattga tttgattgta ctttatggcg
    25861 ttatccatga tattcagcca cacttggtac aaaaactctt cattgcctgt gtaatttact
    25921 gcagcaagtt cgatatccaa ttctagctgt tctttctccc atttaggctg aaaaaaaacg
    25981 attacttctc tgatttgttc atctaatcga tactctttct tttccagttg gatacgctgg
    26041 ttttccagtt tgttcaattt taagatgttc tctgttaatt gtgaaagctg cgtgatactt
    26101 tcgataatcc gatataaaaa tatttggcgt tcttcgtcag agagatttgg ggcttgtaac
    26161 aattgaacat atccttggat tgttgctagt ggtgttttga attcatggga tacactggac
    26221 acaaagtcat tcctcagtgt ctcgatacta ttgagttctt ggaccataac gttgaaatct
    26281 ttatacagtt gctgtacttc tgctactttc tgctgttcat ccattcgaat cgaaaaatct
    26341 cccgttgcta ccagactcat atttgtccct agcgcactga ttggatgcag gatacgccgc
    26401 ccaacaaaaa tcgatattcc tgtacccacg accatactga accccgcaaa gacgaataac
    26461 gggtataacg ttggttttcc agccgattca gcaggcgaga tagaatgtcg agacaataag
    26521 aaaataaaac cgagaaaaca cagcagtgtc actaagatcg aaatgaagac aatactagca
    26581 aaatagatcc ataattgtga aaatagcttt tttttcatct ttaaataacc gccttatagc
    26641 ctagtccccg tactgtgatg atttgaaaat cttccgtctt ttcaaaacgg gtccttaaac
    26701 gtttgatatg tacatcgatc gttcgttctt ctgtattcgt atctaatccc caaatatcat
    26761 ccatcaactg ttggcgagtg aagatcttgt tgggataaga cagtaattta tacagaagca
    26821 gaaattcttt ttgaggcaga atcaacgaat gctgatcttg taacactgta taagcatcta
    26881 gctctaattt tgtttgtccg attatcaagc tactgctgta attgatcttt gaacgtcgaa
    26941 gcaatgcttc cacacgtagg atcatctcat tgacatcgat gggttttgtc atataatcat
    27001 ctgctcctaa tttgaacccg cgtttcttat cctcaaaatc ggcctttgcc gtaatcatta
    27061 gaacaggtgt gtcaaatctg gtgctacgta atgagtctag caagtcatag ccatccattt
    27121 tcggcatcat gatatctgta atgattaatt ctatacgtgt cgcttctagt tttttcagcg
    27181 catcctctcc attcaatgcg gtgatgactg aaaagcccgc tcgttccaac acagaacggt
    27241 aaagcaactg taattgcgga tcatcttcta ctactaaaat acgattcatt gatctccctc
    27301 tgttttttga aaaatttcta gattttttct tgtagttcat cttcagttaa catttatttc
    27361 gtatactacg atcattgttc tgatatactt attagtatac cgaatatttc aatacgggag
    27421 aagggtgatt atgcttcaat taaaagatat aaaaaaatat tataaagtcg gcgaaaccac
    27481 caccaaagca ttggatggtg tgtctgtcgc tttcagacaa aaagaattcg tagcgatttt
    27541 aggtcctagt ggttctggta aaacgactat gctgaatgtg attggtggac tagataatta
    27601 tgattccggt gatatggtaa tcaacggaaa gtctactaaa gactttaagg acagtgactg
    27661 ggatgcctac cgaaacaact ctatcggttt catttttcaa agttacaact tgattggtca
    27721 tctaggcatt attgaaaacg ttgaacttgg gatgacatta agtggtgttt ctaaagacga
    27781 aaaacgaaaa cgggcagaag atgcattgca ccgagtcggc ttgacaaatc atatgcataa
    27841 aaagccaaat cagttatctg gtggacaaat gcagcgagtg gccatcgctc gagcactagc
    27901 caatgaccca gatatccttt tgtgcgatga accaaccgga gcgttagata cagaaacaag
    27961 tatccagatc atggaattga tccaagagtt atcgaaagaa aaattagtga tcatggtcac
    28021 acataatcct gaactggccc atcaatacgc agatcgaatc attgaatttt ctgatggtaa
    28081 gatcttaaca gattcccatc ctcacatcga acgaccaaaa gatgatcaat ttaacttacg
    28141 cagaacaaag atgagttttt ggacagcgtt aaagctttcc ttcaacaata tccgaacaaa
    28201 aaaaggacgt actttcttga cctcctttgc ttccagtatt gggatcatcg gaatcgcgat
    28261 cgttctgtcc ctttcttctg gattccaaaa acaaatcgat aacacgcaag ctgaaacgat
    28321 ggcgaaattt ccgattacta tttctaaggt aacgactaac cagactcgtg acgatgccgg
    28381 attgggtgca agcaaagcgg attatccaga cagcaaaacg attactgcaa aagtcagcga
    28441 agaagataaa gcacagcaca cgaataagat tgatcaaaca tacgtcgatt acgtaacaga
    28501 catcgatcct aacttaagta ataatatcgg atttacccgt actacaggaa tcaatctttt
    28561 acgtgatgta aatggcaaag tacagcctgt cagcttctcg aatcaaaatc ctgatacgga
    28621 atctctttct ttatctagta cgatgtcagc aatgacaggt gtgggagtgt caagtttccc
    28681 tacacagctt gacactagca aagaaaactt tttaaaagac aattattctt tacttgccgg
    28741 aagttatcca gcctcagcaa cagatgtcgt gctgatcgta gacggcaata ataatactaa
    28801 tatcaacgca ttgaagaatc ttggatttga tgtgaaagaa gacgaaaaac ttgattttga
    28861 tgatatcgtt ggtacaacat tcaaattagt aaacaacaat acttactata caaaacttcc
    28921 aactgggaat tttatcccta atacagatta tgatgcgatg tatcagaatg cttctgatga
    28981 attgaagatc tcggggatcc tacgcgtgaa atcttcttct acaatgaatc tcttatctcc
    29041 aggaatcgct tatagcgatc aattaacgac tcaaatcgtc aacgaaaaca aagaatcaga
    29101 aatcgtcaaa gctcaaagag acagtggtgt aaatgtctta actactgaaa aagttgacga
    29161 aaatgccaaa caaacattgc ttagttattt aggtggagac agcttgcctt caagtatcat
    29221 gatttatccg aacaattttg aagacaaaga aaagatcttg gattatctag atgattacaa
    29281 taaaggcaaa tcagatgaag ataaaatcat ttatactgat ttagctggaa cgatgactga
    29341 actgactggc ggattgatgg atgctatcac ttatgtcctt attgcttttg cagggatctc
    29401 tttagtaaca agtatgatca tgatcagtat cattacttat acatctgtga ttgaacggac
    29461 aaaagaaatc ggtgtactaa aagctttagg tgcacgtaaa aaagacatca ctcgcgtatt
    29521 tgacgcagaa acgtgtattt taggtatttc ttctgggata ttaggtgtgt ttattgcatg
    29581 gctagctacg ttccctatca atagcatctt atacaacatg acggatctaa aaaatgttgc
    29641 tcaactaaat cctgtccatg cgattattct agtgatcgtc tctactatat tgacgatgct
    29701 tggcggtcat cttcctgcac gaatggcagc gaaaaaagac gccgctatcg ctttgcgtgc
    29761 agaataaggt tgtgacaacc acatttagat ttgagtcata agagcgctga aatagtagaa
    29821 aacagcaaga aacgaggaag taatatgttc cttgtttcgc gctgtttttt ttaattattt
    29881 tttataattc tggtatactt ttctttcctt tgtaccacaa ctcttctggc gtatacctgt
    29941 cttttccatt tatgaatact gttccatctg cttcaatcgt tacttcagtc ccaatccaca
    30001 tattacgaga aagtgcgaga agattttttc tttttcctct tccttttttt ccaaattgca
    30061 aggcatcggt tatctcttct gtccaatgag atttcacgta ttttacttct ccgttttcaa
    30121 atgtaacttt caaaatattc gctatatttt ccacttttac tgctttagga aatgactcct
    30181 ccattttttt cactttcctt cctccaacac taagtatgcg ctttctttta gtgataagta
    30241 tatcatagtt tattctatta tcaaaaaaac gcatccattc cattgtagaa tactttaccg
    30301 aacaagttga attgttttcc tctttttcac cttttactat agataggtaa agacaactaa
    30361 ggaggaatct ctcatgacag atcaaccgta tgatttaaga aaagtcatcg aagaactaaa
    30421 aacacttcca ggtcaatatc acgaaacaga tattgaaatc gatcctgaag cagaattatc
    30481 tggtgtttac cgttatatcg gtgctggcgg tacagtaaaa cgtccgactc aagaaggacc
    30541 agctatgact ttcaacaata tcaaaggttt ccccggcaca cgtgtgaaca tcggaacaat
    30601 ggctagtcgt aaacgtgtag gtgaaatttt gcaccatgat tatcgaacac ttggtcgttt
    30661 cttgaaagac gctgtagaaa atccaatcaa acctgtgaaa gtagacaaag cagacgctcc
    30721 agcacaagaa gtcgttcatc tagctaccga tgcagacttc gatattcgca acattttgcc
    30781 tgcacctaca aatactcctg aagatgctgg tccatacatc acaatgggtg tagtcttagg
    30841 atcagatcca gaaaaaacaa tgagcgatgt aacgatccat cgtatggttc tagaagataa
    30901 agatacgatc ggtatgtaca tcatgcctgg cggacgccac attggtcact tccaaaaaca
    30961 attcgaagcc ttgaataaac caatgcctat cactatcaat attggtttag atccagcaat
    31021 tgccattggc acgactttcg aaccacctac cactccactt ggctacaatg aactatggtg
    31081 tgcaggagct ttgcgtaacg aacctattca aatcgttgat ggtatagcag tcgatgaagt
    31141 gggtattgct cgtgctgaat tcatcattga agcagaaatc atgccaaatg aaacaatgca
    31201 agaagatatc aacacgaact caggaaaagc aatgccagaa tttcctggct atactgggga
    31261 tgctaatcca gctgtacaag tagtgaaagt caaagcagtt actcaccgaa aagacaatcc
    31321 aatcatgcaa acaacgattg gtcccagtga agaacacgta tctatggccg gtattcctac
    31381 agaagcaagt attcttgcct tggtcgataa agctattcca ggaaaagtag taaatgtcta
    31441 caatcctcct gcaggtggtg gtaaattgat gaccatcatg caaatccgta aagaaaacga
    31501 agcggatgaa ggtattcagc gtcaagcagc tattcttgct ttatcagcct tcaaagaatt
    31561 gaagacagtc attttagtcg atgaagatgt tgatattttc gacatgaacg atgtagtttg
    31621 gactttcaac actcgtttcc aaggagataa agatatcatc gtgatcccag gaatgaggaa
    31681 ccatccattg gacccatcag aattaccaga atataatcct ggctctattc gtttccgtgg
    31741 gataagtgca aaaactatct ttgacggtac agttcctttc gatatgaaag aacattttgt
    31801 acgtgcaaaa ttccaagaag tagaagattg ggaaaaatat ttgaaataat gaatgatctg
    31861 caactgtttt gacatcataa aaaggagtgc ggaaaatgga acaattggca caacggaaga
    31921 aaaaaatcgt gattggtgta agtggcgctt caggcaccat ttatgccatc aacctagtga
    31981 agaaactaaa agaatatccg atgatagaaa cacacggaat catcagtcca tgggcaaaac
    32041 agaacttaaa gctggaatcc gacttatcac taactgaatt cgaaagcctg tttgattacc
    32101 attattcaaa caaagattta ggtgctgctg tcgccagcgg atcatttttg accgatggaa
    32161 tgatcatcgt accggcaagt atgaaaacag tcgcaggtat ctctgttggt ttaggcgaca
    32221 acctgattgc acgtgctgct gatgtaacaa tgaaggagca acgaaagtta gtcattgttc
    32281 ctcgtgaaac gccattaaat gccattcact tggaaaactt gactaaatta gcacgactag
    32341 gtgtgcaaat cataccacca attcctgctt tttataatca gcctcaaacg atccaagatc
    32401 ttgttaatca ccatacaatg aaacttttgg atcaatttga aattgtaaat gagcattcaa
    32461 aacgttggca gggtgattaa tatggaaaaa gaaacgatag ttgaagtaac caaactaggt
    32521 ttcacgatcc aagctgctgt taaagtaatc ggtaaagact tattgatcac tttaacaggc
    32581 ggagatacac cacatatcgg aacagtcact acattttctc gtgatacaga gatgcaaact
    32641 gtacgtttcc ctagccacga tggtcggttc cataaagacg atgtcttagc cgaaaaaata
    32701 gctgtgatca tcaaaactgc cgttccggga agttgtacga tcacttccgg tatccatgtt
    32761 gaccatatct ccaatgcaca aatcaacgcc tcttttccga tgtcagaaga gttaggttac
    32821 aagattttag attggttgga aaaaatagat ttccatatca aataaccagt ttattataaa
    32881 gatggtgaaa aaccattatg aaagaagagg ttgtgaaatc agcgttatga cctgagtatg
    32941 agagaaaaaa atggaaaaat agcttctcat attttgccgt ttttgagcta ataccgaggg
    33001 acagctgatt gaacgccgtt tatcaagagg ttgtgataaa gccgcttcgt ttcgagtagt
    33061 aagaaaaatt ttgtaaacat gggtttccac atttttgcat aaatttgact tactaccgag
    33121 aaactggctt ttgaacaccg tttatcaaga ggttgtgaca cgtcttttgt cacaacctct
    33181 tttatttttg cttcactgta actgctacaa tatcaccgat ttcttttccg atgtttttac
    33241 gaatatcttt tcgtagtcca aggatgtagc agactgaacc atctggattt ttcacgccca
    33301 tattcacgat actgccttca tacggcacat tgtcaaaagt tgcttggact ttaactcttc
    33361 cagcaccgaa ttcttttctt atatcatacg gaaaaataat atatgccccg cccttgccga
    33421 cttcggaagc atagattttt gattcaaaag aataaatttc cctcatttta tttctcctat
    33481 tttttacatc tagtatagca tagcaaaaaa aagaaggaac tgtgacaaaa gtcttgtcgc
    33541 agttcctttt ttcgaataaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata
    33601 gtcaacaaac atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc
    33661 aggctcacaa cctcttcctt aaacggtgtt caaaagcttg catctacggc actaagccca
    33721 atcagatgaa aaatatggag tgctattttt atctgattgt tcttactgct tgatgcagag
    33781 cagctttttc acaacctcct acatggtgtt caaaatatta ttcgcctttt gcttctttca
    33841 ctaattttgc gaatgcttgt tgttggaatt cagcagctaa ggctttcgta cgttgttctt
    33901 gctctgcttt gctcattttt ggattttcag tcattgcttt taccataccg tcttgaacat
    33961 aagcttttgc ttcactttcc atcgtacttt gctgtttctt cactaattca gctaacttgg
    34021 ctgcttggtc cgtacttaat tctacccatg tctctgggat tttgaatgta ttcactcggc
    34081 tgtcatattc gtgattgtta tcagcaatat tgaaccagaa tttatacatg tcgtttttgt
    34141 attcccaata agtagttttc gtcacttttt cagcatcgcc gtctgtcttt tctactttat
    34201 ttgtttcgtt atccgtacca gttgcttttg gtttttcttg tttttcattt gttcggtaaa
    34261 gatacacttt ttcttttcca ttccctaaag ctttatacaa aagcatatct gctccttggg
    34321 aatcagcact ggaaacaatt ttttctgttt ttgtttccgt tactttttcc attccaaagt
    34381 gattggacaa attagcgacg atcaaactta gtgaagcgac gaagattagt ccgaaaatca
    34441 aagataaaaa ggtttgccat gtttttttag cgaacacgtt cgttaaagca aaagcaagca
    34501 agctgacaat caaaactcca ataatcatgc attatccccc gctttcatta gaacaggttc
    34561 ttttttcttc aataaaaagg caataataaa gccaagaatc ccaaagatga tcgctacgat
    34621 aaacgcggca tggtaacctg acagtgtggc attgattgcc tgatctttat aagctaatgg
    34681 cgtattatcc aatacagatt tgcttgggat atttgctttt gtcacattcg tcaacacact
    34741 gatcaaaata gctgtaccaa tcgagcttgc gatttgacgg aatgtattat ttaccgctgt
    34801 cccatgactg atcaagttat ttggcaatgc attcatacca gaagtcgtta ccggcatcat
    34861 gaccatggag atcccaaaca tacggatcgc ataaaggatc acgatatata aaactggagt
    34921 cgtttttgtc aagaaagcaa atggtgcagt tgccgctgtc aaaatgaaca tccctgtgat
    34981 ggctaaacgt ttcgcgccgt atttatcgaa aatcgcaccc gtcacaggca tcatagcccc
    35041 catgatcaat gcacccggca acaacatcaa gccagaatgg aatgctgatt ctccacgaat
    35101 attttgaata tacaatggta cgaccatttc tgcccctacc atcgccatat ttgttacacc
    35161 agctaaaaca gctgcaatcg tgaatgtaga tgatttgaat acacgaagtt ccaagaatgg
    35221 atgttccaaa tgtaattgac gccatgagaa caaggcgatg aaaatcacac caacaactaa
    35281 gaaaccaatt actttcaagc ttccccagcc gtcatctcct acactagaaa atccgtaaag
    35341 taaactaccg aatccaatcg ttgataaaat agcggataaa atatcaatgc taggatttga
    35401 caatggaata acacttttca ttaggaagaa tgctaaaacc aagacaagaa caacgattgg
    35461 cagtaccata ccaaacaagt cacgccaatg gtagttatca atgatataac cagataatgt
    35521 agggcctaaa gcaggagcaa gtccaataac gatccctgac atccccattg ctgatcctct
    35581 tttttctggc gggaaaatag atagcatgat attttgcaat aatggcatcg atactcccac
    35641 accgcaagct tggatcaaac gaccgattag taatgtacta aaattaggtg ctgtaaagca
    35701 agtaatcgtt ccgatcaaaa agatcgtcat ggcagaaaga tataaatttc ttgaactgaa
    35761 tttattgatc agccatgctg ttattgggat catgatcccg ttgactagca agaaaccagt
    35821 cgttaaccat tgcacatcag acgctgaaat atcgaaagct ttcatcaatg taggaaaagc
    35881 tgtcgtcaat aaggtctgat tcaaaacggt acaaaatgta ccaattaata agacaacaac
    35941 taaaagtgtc cgattatatg gttttccgta aatatctacg ggttggttgt tactcatatt
    36001 tctccttctt tctgaatttt ttctgaaact actagaatac tttagtccta aattcgctat
    36061 ttgtcaacct acttgacaca taagttaata cggatataat taagggaagc aagaggacaa
    36121 aaggagtgac aaaaatggtt ggggcttccc ttaaacgttt gttggaaaat gatcaattgg
    36181 ttgttggcat cagtgaatta agtgatatcg taggtgtgtc tccacgtcaa ttaaggtatt
    36241 gggaacaaaa gggattcatt cgttcgatcg aagctgatgc gaattgtcct agaaaatatc
    36301 gtttacctac agtcataaaa gtagaactga tcaaaaaata tttagatgac ggatttactt
    36361 tgtcaaaagc tgcagaaaag gcagaaatcc gccaaaagaa aatgcaccat gtccgtaaag
    36421 ttttttcaaa agcaatcaaa gatatcgaat tgatcgacga acgctatacg attttacaaa
    36481 tcggtaactt caaagaagag aatgctaaga tgtacatcat tcatgacaac gagacagacg
    36541 aattaactta caagctcctt cctgtcgatg aaaaagctga ctacgaacag ttgttaaaag
    36601 aactctaaac gccactaatc tcctaagtac caagcttttt aataagtaga tgctacataa
    36661 atacttgaaa aaaggcctgt ttgaacataa gaatatccga acggtgatct gcgtttcttt
    36721 catatagaaa ggaattctcc atcactgttc ggatattttt ttattttttt cggttacttt
    36781 cttctaatac atctgttagc caatttgcat attctgtttc ccgattgatc gcatgcgcta
    36841 aaatcaggta gtgtccgtaa ttttcatgtt tttctttttc agtaggaaag atcgtttttt
    36901 ttcgctctaa tagatgaagt cgtttttctt catgaaggtc acgctgctgc tgaataattt
    36961 ctactaatgc cggatcattc acgtctttga cgaaatacaa tttcagaaca aattcgtctc
    37021 gattaaccgg tagttcattg gtgggtgtat gaatccactc tgccaattgt tccttccctt
    37081 cttctgttaa ttcataaact ttcttttcca atttttcacc tgtgatctct acttgatgct
    37141 gaatgattcc ttgctcttcc atttttgcaa gttcaggata aatctgacta tgttttgctt
    37201 gccaaaattc tcctatttca tttttgaacg attgattcaa ttcatatcct gtcatcttct
    37261 tcttacttaa taaccctaac aaaatatatc gaagtgtatt ttttcttgcc atcagttttc
    37321 cctccttgac aaatctttaa atccattcta tcataaatga gtaatcgaaa acatgtagtt
    37381 tattacatgt tttaatttat aaggagatgc ttaaacatga aagaatttaa agaattggaa
    37441 gattttattg gaactcactt tatctatacg tatgacaatg gttgggaata tgaatggtat
    37501 gccaaaaatg accatactgt tgattaccgt atccatggcg gaatggtcaa aggccgttgg
    37561 gtaaaagacc aagaagctga tatcgttaaa ttgacggacg gcgtattcaa aatcacttgg
    37621 acagagccaa cagggacaga cgtggcattg gactttatgc caaatgaaaa gaaacttcac
    37681 ggaatgatct ttttccctaa atgggttgaa gaacatccag aaatcactgt tactttccaa
    37741 aacgaacata tcgcagaaat ggaagcagct cgtgaaaaat atgaaactta tccaaaatta
    37801 cttgttcctg aatttgctac gatcacttat atgggtgatg caggtataga caatgaagat
    37861 gttattagcg aagaaccata cgatggaatg ccagatgata tccgtagcgg aaaatacttc
    37921 gatgaaaatt ataaacgagt aaaataaggt tgtgaaagag aggttgtgaa atcagcgttc
    37981 tgacctgagt attagagaaa gaaacggaaa aatagttcct catgttttgc cgttttttga
    38041 gctaataccg agggtcagct gattgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38101 atgctttgag taataagaac gctagttaga aaatagcttt tcatattttc taggctagtg
    38161 ggcttattac cgagaagcag ccgtttgaac accgtttatc aagaggttgt gaaatcagcg
    38221 ttttgacctg agtattagag aaacaaatgg aaaaatagtt cctcatattt tgccgttttt
    38281 tgagctaata ccgagggtca gctgattgaa caccgtttat caaagattgt aacaactgca
    38341 tattcacaca gttaaattag tgacttcaaa atgaaataat gctcccagca aaaaattagg
    38401 ctgggagcat tatttcgtta ttctgttcat caaaaatcag cgttttgatt ccatttcatc
    38461 acaagttcct cctcatttac tgcttcatct ttttgctgtg tttgaattgt aaaaccttgt
    38521 gaaagataga aatgaatagc tgattgattt ttttgataga ctgtcaaagt cagtgtttta
    38581 ttggtttctt ttattttttt cattagttgc gtaccgattc tttgttgccg gtattccctt
    38641 ttcacaaaga ttcctgcgat aaactgatca atcaccccag caaaaccaat aatttcttga
    38701 tctatttctg ctaagtaaat cactgcatct ggtaaagctt tcctaacaga ttctacttga
    38761 ttctcccaat aagttgatgg aatgaattca tgagaatcca agttagcatg cagccaaatc
    38821 gatagaacag attccagttc tttggcagac aattttgttg ttgtgcggat cattttttct
    38881 ctccttactt attcattgat tttaaaataa aaaccatttt tttgaagctc ttttacaagt
    38941 tttcgcccct caaaaaagta tatcttctct tgttttactt ttctaatacc aaaagaaaca
    39001 gcaactttag gatcatcagc tgaaacgatt cgataagttc caccaggcaa ttgatccagc
    39061 ttgactttcc catgatggtc gctttgtact gaaaacggca caccatttct agtaagtgtt
    39121 tttttcttat gtttcaaaat gaatgaacta ccatttaccg gtttccctga cgaatcacta
    39181 ataataaatg aaaaatcaag cactttttta cttaatctat actgatagat tagtcgtccg
    39241 ataaacacta acagtatgac tacagctatt atcgttcctg caagaataaa ccattgccgc
    39301 atggttcttt cctgatttcc ttttccttct tcttttttta ccgattcgtt ataaggaatc
    39361 cgatgtcctg tcactagcaa acgatgcgtg ttgatcatat acggcgtaca tgtaagcaag
    39421 gtaactaagt cttctccttc tgaaatcgtt agaacagacg tgtcatctgg cagtaccact
    39481 tgtatatttt taacttgata agccaatttc tcccccaaaa cagtcaaaat aaacgtgtct
    39541 ccgttttcta aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc gctgtgagca
    39601 gagatcactg aatgcgtcga atttccacca agcgggaaag aggttccttg caagacgcct
    39661 gctccatttt caaggatcct accattgagc cgatcataaa gtgaaatatt taattggatc
    39721 ttaggtatat tgatacttcc gatcagccat tcctctaatt ggctggatgt tgtactttca
    39781 tttctgttct tttcattgaa aggatcagta ccaggattga atccttggtc agttaatcgt
    39841 tggtttttct cctccatttt ctttcgctgc acttcaattt cagctgcggt ccgtttttgt
    39901 acttgttcga tacgtttttg atcaataaaa ctatttaaag aatccacata aaatggatat
    39961 aaagcgatca gtaaccctac gacgatacat attaataaaa acaaacgaaa caaaagtcga
    40021 cgagactgtt tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt tttttgttct
    40081 ttcttttatt atatgggttc aggaaaaaaa tagaaaatga aagccgatga ggttgtgaaa
    40141 aagctgtcct gcatcaagta ataagtacag cccaaaaaaa tagctactca tattttttgt
    40201 tgggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg
    40261 aaaactgcgt tatgctttga gtaataagag cgctagtcag aaaatagctt ctcatatttt
    40321 ctaggctagt gagcttatta ccgagaagca gctgattgaa caccgtttac cgagaggtca
    40381 tgaaaaagct actttgtttc gagtattaag aaaaattctg tttcaaaaca aggagatgca
    40441 acaaaactta tgtcgcatcc tctctcctta gaactttcac ttatgttttt cttgtaaaat
    40501 tcataaatat tttcatgaat tttctaattt cttgcctacc tctcgcatag gatatatgat
    40561 gaatttatct aaagtttgca aaggagttcg acaattgaaa aaatatggcc catttttagc
    40621 aatttttttc attgctttgg catttctcat gcctcattta ttcacacata aactaatttt
    40681 gggtgctgat gccccattcc attacaatcg gttctatgat gccgcgcaac aaattaaata
    40741 tggggatttc cattattttc cttcccttta tggattccag caaagtggca ggatcgtgaa
    40801 tgccgtttac ggcccatttt tcgcttattt acaaggattg atcgtgttgc ttgcaggtag
    40861 ctggtttcat tatcagattc tttcaaattt cattctttat cttatttcag gattttctat
    40921 gctgatttta ctgagatatg tcaatgttcg aaattgggta agtgtaccag tagccgtttt
    40981 attcatgagt acgtattcta ttcaatactg gtctatcaac caaggattca ctagctgggg
    41041 gacttgtttt tatcctttat gtatgatccc tattgctgat ttcgtccttc ataaaaagtt
    41101 ccctgttatc aaagtcgctg tctcagtggg acttatgaca cagatccatt tactgtcttc
    41161 gatcatgtta gctttgatgt atatcccttt ttatctttat tactttttta accagactga
    41221 aaaaggaaaa gcactgcttc aactgattaa gtcggtcttg ctttattttg ttctgacagc
    41281 aaatatttgg gcaggattag ctattgttta cagtgggaat aagattcttc ctccctttgt
    41341 taacagagaa atgagtcaaa aggcgataga tctggatggc agttattggc tccattaccc
    41401 taaggccttt cctatattga tattatcagg ttttttgctt tttattttct ttcaacaaaa
    41461 gaacacctta ttccaaaaaa tcgtgttgta cacaagtctt gttttctttt ttctttctac
    41521 tagcttgatt ccatggacga cattgatcga aaaaaatgtg ccttttatta gtttgatcca
    41581 gtttccattt cgatttttcg tgccatttac gctattgctt ctactttacc ttgccctttc
    41641 actgaaccag tggtctgaac aaaagtggtt ccgtctttta agtatatttg gcattcttat
    41701 tttttcagca cagacgatcc agaacttata ccagcatctg gaaaagtggg aaaatgaaac
    41761 atttgtcagt cgacatactt atctattcga tacgccggaa gaagcaagga aaacattctt
    41821 cagcaaagat atgtctacca gcttgttcgt tttccaaaaa accacacctg actatctgcc
    41881 aatctataag gagacaaaag acaataaata cgaccggtat aacgaagaaa tactagaaaa
    41941 cgaaacaact tttataaaaa cacatccagg cggtcttttg acaatcaagt ggaaaaacac
    42001 tggggacaaa actgttcata tccctgttat cgtctacgat cggactgtgc tacagcaaaa
    42061 tggaaaaaca ttgactgatt atgaagtaac agatatcggg accccaatcg tgaagcagca
    42121 aaaaggaatc aacgagctca cgcttcatta tcaaacgcca atctatttct atttcattct
    42181 ttctcttact ttgattggct ggtttacctt gctatgttta tttatttatc atagatacaa
    42241 gcttttacgt gcttaggcaa aagggataaa tacatccgat caaaaaactc tccaaacggt
    42301 ataatcgttt ggagagtttt attttaatca gtttttttat gttatatgtt atatttttta
    42361 ttcgttcaca tctaattcga tttccacccc gtagtgatca ctgatgattg gactatcgat
    42421 cccatcaaaa atccgttgat attttttaac ctgcattcct tcagggacga aaataaaatc
    42481 tatacgcaat ttttctgtat tttgttccca accatctatt ttcttttcca cagtagctgc
    42541 ttttcctttt tcattcgcga caacatacga atcttgaaga agaaggcaac tttctcttac
    42601 agtataataa ccttgagagt ctactggatt attgaaatca cctaggaaaa aaagtggtac
    42661 gcgagtttcc aaaaagtagt tttccaagtt tttccactca aaataaaagc cacttttttt
    42721 atctgtccac caagaaaagt ggcagctcga gacaaaaatg tcctgatcat ctatctttgt
    42781 tttcccaatc aagatcttgc gtgtctgata atcttctttc ttttgaaatt gggagacggt
    42841 aaggacctga ctttccaatg tttttttcgt aagcagtgca tttccttctt catatttatc
    42901 ataaccgatg tggctcattt cccaactcca aaaatactct tttccgtgtt cctttaaaag
    42961 ctgaactaaa cggtaggcaa aattatcttt acggataggt acttgattct ttaccggaca
    43021 gaacttcatt agcttcgcag gttctacttc ttcagattcc agtaattggt tgatttcttg
    43081 taaagcaatc acttcataat cttctaacag gatcttatct gctaattctt gcaatttttt
    43141 ctctggttct ggctcaagcc agctatgcgt gttgagtgtc atgaatttca ttggttttct
    43201 ccttgtcttc atttcgaaac aaaagggttg tgacaaaatt tttgtcacaa cctctccagc
    43261 aaatagtgtt ctcctgctaa ctcctcagta ataagctcaa tggaccagga gctatttttt
    43321 gtttggctgt ttttatcact tggtgcaggg cagctttttc acgacctctc cactaaacag
    43381 tattcaaact gctgcttctc ggtaataagc ccaaccaaac gaaaaatagg aggagctatt
    43441 tttgtttggc tgttcttatg acttgatgca ggacagcttt ttcacaacct ctccttacat
    43501 tttaatggag ccgatcactt taccagctgt cactgtacct aattgcttga tcactacttc
    43561 ttctacttta tcgtttgtaa atacgatcat gatcgttgga tctttttctt cgttttggat
    43621 cacatcaaga tccatctcag ctaatttcgt tcctgttcct acttcttggc cttctttgac
    43681 agcaatctca aaagctggct gattcatttg gactgtatcg attcccatat ggatcaaaac
    43741 ttcgatacca tctttcgttt ccagcccaat tgcatgtttg ctagggaaaa tacttgtcac
    43801 ttttccagcg atcggcgcaa caacttctct tgatgttgga ataacagcaa agccgtcacc
    43861 catcattttt tgtgagaata ccggatcttt tacttcagat aaaggaatca cttctccaga
    43921 agctgcggaa actagttctt gttctatacc taagtattgc ttactacctg cttgtccatt
    43981 tcctgtagaa accatttctg gctctggaat ctctgctcct gattgcagca gatcttcgat
    44041 atctgatttc aagacatctg cttttggtcc ataaactgct tggactccat tgtctttgac
    44101 gatcaatccc atcgcccctg ctcgtttcca ggcttcttca gtccctactt tttctcgatc
    44161 atttacactt acgcgtaacc gagtcataca agcatcgaca tctttgatat tttcttttcc
    44221 tcccagcaaa tgaatgatct ggaccacttg ctgatctgct gttcctgttc cgctgttaga
    44281 tacaacggtt tcttcactgt cattgtcgta atttccgtta cgtcccggtg tagcaaagtt
    44341 gaattttttg atcaagaaat ttgctaagaa atacgtaaca acaccaaaag cgatcacaca
    44401 caacacgaag ttgataagat ctccacctag acccgctttg atagctaacg gtgtccgagt
    44461 cagcaattcg atattcccaa atgaatggac ccgcaatggc aagatatctg ccatcgcaaa
    44521 tgcagcccct tggatcactg aataaatgac atataatggc acagcagcaa acataaacat
    44581 gaactccaat ggttctgtta cacctgttag aaagacagcc aacgctgctg aaaaatacat
    44641 tgatttatat cttgctttct tatcaggatc gacattacga tacatcgcaa aagccattcc
    44701 catcaagata cctgaagaac caatcatttg tcctactttg aaacgagccg gcgtccagtt
    44761 atgcaacaca aactcatatt gcgacatatc ccctgcacct ttaagattca ctaaatcagt
    44821 ggcccaagcc aaccataacg gatcttgccc aaatacttgt gtccccgcct gtgcgcctga
    44881 taaaatctca tacgatccgc caagctgtgt atagttgata ggaatcgtca gcatatgatg
    44941 caatccaaat ggcaatagta aacgttctaa tgttccaaat aaaaacggtg ctagaatcgg
    45001 tgcgctttct tgtgattctg caatccataa accaaaatta ttgattccag cctgtacgtt
    45061 tggccacacc acagcaagaa tcaatgccac gattgttgac cataagataa caacaaacgg
    45121 aacaaagcgc tttccattga aaaatgacaa agcatccggc aattttctat aattatagta
    45181 cttattataa gccattgccc cgacaaatcc agcgatgatc cctacgaata ctcccatatt
    45241 caaagctggt gcttccaata cacttgtaaa aaatccttta accatgatct tcgtaccgaa
    45301 cagagtgtgg gtaaatgcat cttcattcgc aagcatgtca cttgtgacac caaagatagc
    45361 cccagtgatc cgattgatta aaataaatga gatcccagct gcaaatgctc cgcctgctct
    45421 ttcttttgcc caacttcctc ctattgctaa agcaaataaa atatgaagat taccaataat
    45481 tgcccaacca atattttcaa ttactccgcc cgttgtgaca agcggcgtcc aatcaggatt
    45541 gatcaaggga attgatttcc ctatactgat catcaaccca gctgccggca taactgctac
    45601 cacaaccatt aaagcctttc caaatttttg ccaaaactca aaactaaata tctttttcat
    45661 tccgtttagc tcctttacgc aatcggtttc gttaaacgta ttatagcgtg cgttttcttt
    45721 tttgtaaatg ctttattttt tatttttctg tctataccat tctataaaac ctataatacg
    45781 tgtgttccct tctataattt tctcctaaaa atttattttt ttaagctttt ttctatgaaa
    45841 tattttcttt tgtctattga cttgtgcaat cggttgcgtt tattatgaac gtataaaaca
    45901 gctcattagg aggagaaaaa tgaaacagat caaacgacta tttgctattg atccatggaa
    45961 aatcagcacg acacaattag ataaaaaaaa tcttcgactg caagaatctt taacaagtat
    46021 tggaaacggt tatatgggga tgcgcgggaa ctttgaagaa acttactcag gggaccacca
    46081 tcaaggtact tatttggcgg gtgtctggta tcccgataag acacgtgtcg gctggtggaa
    46141 aaatggttat ccagaatact ttggaaaagt gatcaacgcc ttgaacttta tcgcgataga
    46201 tatttcgatc aacgatcagc tgatcgactt ggcttctttg gaaccagaag acttttactg
    46261 ggaattagat atgaaaaatg gtgtattatc tcgtacattc acaatcacta cttctactaa
    46321 taaagtacgc atttccttcg aacgttttct gagcattgtc aaaaaagaat cagcttatat
    46381 ctatttaact atagaaatgc ttgaaggtag cggaacagtc aaactcgtat caaaattgga
    46441 tggaaatgtt caaaacgaag acagcaacta tgatgaacat ttttggaatg agattgatcg
    46501 tggaactata gaagaaatcg gctatttgac gactaaaact attccaaaca actttgggat
    46561 tgaacaattt actgttactg cagcaatgcg ccatttcgtt aatggaaaat cagtcatccc
    46621 tgactatcac gaagatactt tagcattaca tggttgcttg tctgcagaat tatctcaagg
    46681 tgagacatgg tcagtggaaa aagaaattat cgttcttact agtagagata ttccagaagc
    46741 gcagcaagca gaaaaagctg tctcagaatt aacgaaccag acaaacaatt atatccaagc
    46801 aaaagaagag caaacagcgg cttgggcaga acgatggaag cttgccgatg tggtcatcga
    46861 aggagacgaa gaagcacaac aaggtattcg attcaatttg ttccaactat tctctactta
    46921 ctacggcgaa gatgaacgat tgaatatcgg ccccaaagga ttcacaggag aaaaatacgg
    46981 cggagccact tactgggata cagaagcgta tgctgtccct ctttatcttg ctttagccaa
    47041 acctgaagta actaagaatc tgctgaaata tcggcataat caactgccgc aagcaatcca
    47101 caacgctcag caacaaggat taaaaggcgc gctttatcct atggtcacct tcactggtgt
    47161 cgaatgccat aacgagtggg aaatcacatt cgaggagatt caccgaaatg gcgcgattgc
    47221 ctatgcaatc tacaattata cgaattacac cggcgatacg gaatatttga aaaatgaagg
    47281 actggaagtt ttagcagaaa tcgcacgctt ctgggcagac cgtgtccatt tttcaaaacg
    47341 agcaaataaa tacatgatcc acggtgtgac cggcccaaac gaatatgaga acaatatcaa
    47401 taacaattgg tatacaaata cgatcgcagc ttgggtcttg cgttacacgc gagaaaatta
    47461 tttaacttat caaaaagaag ctgctatcac tatcagcgaa gaagaactag ccaaatggaa
    47521 agatatcgca gagaacatgt acttcccagt tgacgaagaa ttaggaatct ttgtccagca
    47581 tgacacattc ttagataaag atctcatgcc tgtatccgat attcccacaa gcgatcttcc
    47641 tctgaatcag cattggtctt gggacaaaat ccttagatct tgcttcatca agcaggcaga
    47701 tgtactacag gggatttatt tcttcaatga tacttttaca aaagaagaaa agcaaaaaaa
    47761 ctttgatttc tatgaaccaa tgactgtcca tgagtcttcc ctttcgccaa gtatccattc
    47821 gattttagca gcagaattag gaatggaaag caaagctgta gaaatgtacc agcgaacagc
    47881 tcgcttggat ttggataatt acaataacga cacagaagac ggcttgcaca tcacttccat
    47941 gactggtagc tggttgtcga ttgtccaagg atttgctcaa atgaaaactg cccatgatca
    48001 gttgagattc gcaccatttc tgccaaaaac ttggaaagct tattctttcc atatcaatta
    48061 tcgcggacgt ttattgttca tctcagtcac agatgaacaa gttactttcg agttattaga
    48121 aggttctcct ctagaaattt acgtctatga acagtcttat tctttagcgg atcgtctaga
    48181 aataacgcta agaaaggagg aagcaaatgt ttaaaggggt attgtttgat ttagacggtg
    48241 tcattaccga tactgctgaa ttccattatc gtgcttggcg aaagcttggt caggaaatcg
    48301 gcattacgat cgaccacaca ttcaacgaac agctaaaagg cgtcagccga gaagactcac
    48361 tctctttgct tttagcttat ggcggaaaag aacactcttt ttcaaaggaa gaatttgcag
    48421 aattagcgaa aagaaaaaac gattattatt tagagatgat ccagacgatc gaaccaaaag
    48481 atgtcttccc cggggtcgtg cctttactgg attctttaaa agaagaaaaa atcaagattg
    48541 ctcttgcttc tgcaagtaaa aacgggccat tcctacttga aaaaatgggt cttacacctt
    48601 actttgatgc tattgccgac ccggcagaag caacaaacgg aaaacctgcg ccagatatct
    48661 tcctccttgc agcaaaagct gtcggactaa aagcagaaga atgtatcggg atcgaagacg
    48721 cgcaagccgg tatccaagcc atcctctcaa gtggcgctca accaattggc gtgggacgtg
    48781 ctgaagacct tggagaggag atcccgcttg tccctgatac gacttttctt acgatcgatt
    48841 acttgaaaga aaagtggcat gaccatggat aatccagaga tctccgtcgt accagttcca
    48901 gagactgaaa taaagaaaat cacattgaag aacgactact tagaagtcgt tcttctcaat
    48961 tacggtgccc gcctgcacca aatcttcgca ccagacaaag aaggaaaatc agaaaatgtt
    49021 ttattgtctt acgatcgttt cgaagatgtt ctaacagaca aaagcttttt tggagcaact
    49081 gtcggacctg tagccggaag gatccgggat gcttcttggg gtgagcatag attggagaaa
    49141 aactgcggat cacaccatat ccacggtggc acgaaaggct ggtctttcca attttgggaa
    49201 gtagaagttt tcaaaactcc atcatcaata ggtgtggtct tttacttaaa agatgaattt
    49261 tctacctatc caggaccaat cactgctacg atcacttacc gtttaacaaa aaacgaatta
    49321 gagatgacaa cctctgctag tagccttgtt gaaaccatct gcaatccgac caaccatgcc
    49381 tacttcaacc tttcaggaaa tggaacaaga gacatctatg aacatcagtt aacggtcttt
    49441 ttagatggtg tgcttgaatt agatcaagaa aaactgccta ctggaaattg gacaaaaaaa
    49501 gaaaaactgc caatcgactt tagaaaatcc ccaacactgc aagagatcct tgcatgttat
    49561 ccagatggac tagatgatgt atttcttttg catcatccta ggctttccaa aacttcctta
    49621 caattattcg agaagcattc tggtcgccaa atgactatag caacttctaa taaaagtatg
    49681 gtattatttt ctacgactgg attcgaagct gatttctctg tcaatggaaa acagatgcat
    49741 tcaaactacg gattagcaat cgaaccgcaa gaaatccctg atatcgttca tttccccaaa
    49801 tttggatcga tcaacctcca tcctggtcaa gaacggatca gtcagacgat ttatcggttc
    49861 tctgcacaat aacaagagaa aggtgttttt atcatggcta ttaccgtaaa agatgtggcg
    49921 aaaaaagccg gtgttgccac ctcgaccgtc tctcgtgtca tcaacgatca tcctagtatt
    49981 tccgagacaa caaagaagaa agtccgaaaa attatggatg aactaggtta tgttcctaac
    50041 atgactgccc gcaatctagg aaaacgcatt tccagtgcca tcggcgtaat cttaccccct
    50101 cttgattcaa aagagcggat cggtaaccca ttttatcttg agatcatgga agcaatcaac
    50161 gaagaagcgc ggaattatga tatgactaca gcaatcgcta ctgctaaaaa ttttgaattg
    50221 ctgttagaga acgtccagcg tatgcattta caaaaacaag tagatggttt tattctagtg
    50281 tattcagata gtcaagatac tgtcattgat tatttatacc aaaaccacat ccctttcact
    50341 ttgatcggac agccttatca tcatgagaac gaaatcgttt atgtagataa tgataaccag
    50401 cttctaggta aacaagcaac agaatttttg atccagaatg gacataagaa tatcctgttt
    50461 gtgacaaaca cgactcatga aagtttgtat ttcgaacgat atttcggtta tcaaaaagca
    50521 atgatgatgg ctggtcttcc tgcgttatcc agtgtagtac tagagcatcc ggaggattat
    50581 ctgtcctttg agaaaacgtt gaaagaaaac gaagccacag cattggtggt cattgacgat
    50641 atcttcgccc ttcgcacgat gcagttggcg caaatgtatg gctatgtcat tccagagaca
    50701 ctctccgtca ttagcttcaa caactcgatc ttctcaacat taacacaccc ttaccttaca
    50761 agtatcgata tcgatatctc cgaattagga cgtgtcgcta tgcaaaagct gcgcgaattg
    50821 atccatgaag aattgagcag tggcgtacgt ttggtcatcc ctcatcgctt gatcaaaaga
    50881 gagacagtcg ttcctttaga aaacccatac taaatagctg actcactaaa tacgctgacc
    50941 atttatccta tggtcagctt tttatgtaaa agaagatact acttctaaca cattgtttat
    51001 ctgtaaaaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt
    51061 ataaacggcg gaagcagaag caactccttc ggaaataagc tgaaattcac aaaaatttaa
    51121 aaagcaattt tcttgagttt cttcttattt cttggagtta aacgcttctg tcccagcctc
    51181 ttttttcctt ccttcaattt tttacacgtc gacgattcaa taaaaaaccg cctaatattg
    51241 taaagacagg tgcaagaatc gagaaaaagg cgaatggcaa gtaatgcaac gcgctaactt
    51301 tcatcgttcc cataatgaat gtgccgctga ctccccacgg tacgagagaa ttgacggtcg
    51361 cacctgaatc cgctagtgtt cgtgtcaaat aggtttttga taagccaacg tcatcaaaag
    51421 aacgcttgaa tgtttctcct ggaagaatga tggacagata ctgttctcca acgatcagat
    51481 tgattccgat acagctcaag gcagtaaacc cgactaaacg agaaggtcgg tccatctttt
    51541 cttttaattc ttgaacgatg gtatcaacga tcagatattt gatcagtaac ccacctaatg
    51601 ccaatgcaag taaaatcaaa ctagcagaac ctaacatact catgatcccg cctcgagaaa
    51661 gcagttcatc tagctttgga tcaggtgtat ttgcgacata accattcatc aagatgtctg
    51721 ctgcttttcc gaccgtcaaa cttttctcat ggataaaaga aagaacgaga gcagctgtcg
    51781 atcccgctag taatgtaggg atagccggaa tttttttgat tgccccccca aataaaataa
    51841 ctagtggaat caatgtccaa ggagagatcc aaaagctcgc tttcatgttt tggatcattt
    51901 cattgatact agctagatcg gctgaatgac tgttatgtcc taatatcgta taaaaaatca
    51961 acgaaaggac gaatgctggg aaatccgtat aacgcatacc agcgatatgt tcgaatagat
    52021 taactcctcc aatacccgct gccaagttgg tcgtatctga taaaggcgag cagttattcc
    52081 ctaaaaaggc accggaaacg actgcgcctg tagtcattgc atcattgaat ccaagtaaat
    52141 gaccgatccc caaaaaagca attccaatcg tcgaaatcgt tgtaaatgaa ctgccgacag
    52201 tcactccgac aattgcacaa acaagaaatg ctgtcggtaa aaagaaacgc acagaaacaa
    52261 gtttaaatcc ataaaccata atcgtaggga tggttccaga taaaatccat gaagcaacta
    52321 agacaccaat caaaagaaaa atcaggattg gaatgatccc tggagtgatt cctttgatga
    52381 tcccgtcatg gatctcatcc catgtgaact ttttaaatct gccataaaac aacaaacaca
    52441 tgaaagctgc aaggatcggg atatgtggcg agagctggaa tccgatgatc agtactccta
    52501 ggagtgccaa caacacgatc aatacagcga tactttcttt taaagaaata tttttattca
    52561 tcgtcgatct cctatttcaa atgaaaaggc cctgccatga aaaaactatt cacttggcag
    52621 gacctcctac taaatcagcg acaaaacgtc ggctgaaaga cttatttttt tatttttctt
    52681 ctaaactttt ttctacctca atcccccaag aatctttctt gaagtgattg atgatcaatg
    52741 gaataacgaa catgaccact gtgatagctg ctactaataa tgcatcactc aatgtcgctg
    52801 tacctaatgt agcaaatacg acaacgatga tagagaagat cagcatgcag ctgactaccc
    52861 aagctaatcc gtttccgttt ttaccaattc ggtaaggacg ttcgaattct ggatgtttct
    52921 tacgcatttt aagcaatgaa acagcaatca aaatgtacac gatacaataa ataacagttg
    52981 tagcatttgt aagtgtcaag aatacagcac ttacgtcatc cattacacca taaagcaaag
    53041 caaataatga aataacgatt gattgtgtta gaacgacatt tctagatacg ccgtatttgt
    53101 tttctttatg gaatccgaat tttggtggaa ggaatccttc acgagctact tggatgattg
    53161 tttttgatgg tccagtaacc caagctgata attgtaaaag cacaccaata aataccatga
    53221 agctgaagat atttccgatc acttctggta agcctaggat ttgacagtca atcaagatag
    53281 gctgcgtgat atttgctaat tccatttttc catctggtac gacatttgct acaagcatcg
    53341 cattgatgac attcaataaa actaatccga tcaaagcgat aaatacgcct tttgtataat
    53401 tttttgttgc gtctttcaaa cgaggcatgt aaacagaact catttcgatc ccaacaaaaa
    53461 taaatgtgat accagctaag tatttcaatg aatcaatatg ttccaagtca gggaaagctt
    53521 ttgaccatga aaagtcacct agatagccgt ttgagactag tccgactttg aaggctgcca
    53581 aaacacctaa aacgaacatg atgactactg ggatatatac ccctagccat acaccgatgt
    53641 tcccgccgac ttttgccata tcgaatttca agttcaagat cgtgatgatc cagtagataa
    53701 ctaaaataca acctaaaacg aaccagtgat tattgccaag ttctacatta ccaaatgtgt
    53761 ttcctaacaa tggtcctaaa gtagaagcga ccattaccat acctgggaac atttgcaccc
    53821 ataatagcca tgcaacgaca aatccccatt tgctgcccag tgctgttttt acccataact
    53881 gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc ggaaaccatt gatatcggac
    53941 cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa tgtccaaccg actgcggcta
    54001 acgtaggaat actccgaacc gttgcacaca gtgccattgt cagaccgata aaggtcccaa
    54061 gacccatttt acttacttca gatttactca ccgttgacac tctccttgat tttttggata
    54121 aaataacggt gtctttgaag tagtttcagc aataaacgaa acaattcagc gaatatttga
    54181 ggggattctt tgagtttatt gcttgaaggg tttcttcaaa gacaacctca aaacaaaggg
    54241 atcgaagagc ttaggtctcc ccttgctctt cagatccaaa catgcgtcag aaacagttag
    54301 tattcaagct gttttctaac atgattacct tgcttatttt gcttcgcttg ccaataattg
    54361 gtctgcgtag attttttcca atttttcttg aagagctgct ttgatttttt cagcatattc
    54421 ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg ctggcacgca atacagttac
    54481 ttttccggca cggttccatt cttcatctga gaatcctagt tggttcacaa attgtaatgg
    54541 gctgttgcca tagtctggga tagcaaagtc agtatgtgaa gttaagaact cattaccgta
    54601 aatgcttcct ttcacgtatg aagaataatc atatacgtca tggttcaatt tattcattgc
    54661 aactaagtca tcgttgcctt tttctttgaa tacatagtct accatattga aatctggata
    54721 agttaatgga tgaacttcga tttctttgtc tcctacttta aatgacaagt cattcaagaa
    54781 gttgtagaaa cgatgtgcac cttcgattga tgcacccatt aatttaccat atcctgtgac
    54841 attcaaaggt aagacatggt gtgctgccca aacgctggct gctgttgccc ctgcttttga
    54901 accttccaag atataagccc caagtaatgc tgggatatct gcgccttttt caaatacata
    54961 tgtcgcaaag taagagataa cgtctctcat gcggatatct ttgatgacga taccaccggc
    55021 agaatatgga acatagccca ttttatgtgg gtcaatcgtt acagattctg cttcttcgat
    55081 tgctttatat gcactgtgta cttcttctaa gatataatct ttgttttctg taaagacatt
    55141 gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg aagttgttgt cttcgtctaa
    55201 gaaaatcgca cggccgtatc cgccataagc agcatctacg tgtaagtaga agtaaatacc
    55261 gtctttttct aatacgcgac gcaatgcaac gattttatcg ataccgtcga ttgctccttc
    55321 ttctgttgat cctacaacac cgactacacc taggattggt gttttttcag ctgctagacc
    55381 acgaacgatt ttttcaagtt cgttgatgtc catgcgatag ttgtggtcaa ctggcactgg
    55441 aatcacttgg tctaaaccga taccgatgat gtcggcagct tttagccatg aatagtgttt
    55501 agtttgtgga accaaccatt ttcctaattt ttctaaatgt tttccgctac gtgctgagtg
    55561 agctttgatt tcgtcgattt tttctgggac gctgtctaac agattcatga tttcttctgt
    55621 tgacaagttc attaattccc aatcgctttt tccagcaact agttcaggtg tcacttcttt
    55681 cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa agtccttcta agtttgctaa
    55741 agaaccatca gcaacgatgt ggccccagcc atctttatag ctcattaatt ttgcaaattc
    55801 cattcctact tcttcttcca tttggcttgt tgcaggagaa gattcatagg caacgttatt
    55861 accattccat agcatagcaa aattgtacgc tagtaaagat ggcatcaatg tttcagagtt
    55921 catatgaccc cagtaacgtc cggcattatg ccaaggaacg gaatgggtac gcatccgcgc
    55981 tgaaatttct gatagaacat cctttgtttt attcacagtg tgttcaaaac tagcactgct
    56041 tttttcttct ggcgtaataa taggcatgtc ttgaggcatg tagttttgac gccagcctaa
    56101 atgttcatcc accaattcat tcaacaaagc tttatagatt tggccgttct cagctttgtc
    56161 cccaatgaat agggcattta ggtttagatc tttcgacaat gattcactca tagtgaaacc
    56221 ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta cacctgttct tctattctgt
    56281 aaactaagtt ttggcctgat ttttaatcat attttaatat gtatcaatta tccgaattgt
    56341 tcacactttt gaaataatta aaaaaaacga gggaatttac aaatgtaaac tccctcgcaa
    56401 agattgtatt aacgacaacc agcgttctat tttaggatgg gtttcaaaat tggaatgttg
    56461 taatagtatt tccctttttc aaggtaaaaa cttactaaat tctaatcaat tactttggcc
    56521 aaaaagtaat ttttcttacc ttttcgaata accacaaact taccatcgaa ttcatcggat
    56581 ggatttatga caaaatttaa atcggtaacg cggtcaccgt taatacttat agctccgttt
    56641 gaaacatctt cacgtgcttg acgtttagat ggttcaattt ttgtggaaac aagcagttcc
    56701 acgatatttt caggtgtgct tgaaatttca acgttcggca ttttaccgaa tccttgcgcg
    56761 atttcttccg catttagttc tttaatattt ccagagaaca atgcttgcgt tattttttgc
    56821 gcttctttca agtcttcttc actatgcaca aatcttgtaa cttcttctgc caaacggcgt
    56881 tgtgcttcac gtttctcagg ttctgtctct acttttttcg ctaagtcttc gatttcttct
    56941 tgagacaaga aagtaaagaa tttcaagtat ttcactacat cgcgatcatc ttgattcaac
    57001 cagaattggt agaactcaaa tggtgaagtt ttcttcggat caagccaaac ggcaccgcct
    57061 gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca atgggatcgt taaaccgaac
    57121 gcttctgctt ctggtccttc taattttcgg attaggtcta atccagctgt gatatttccc
    57181 cattggtctg ctccaccgat ttgcaattgc acatcgtatg ttttatgcag atgcaaaaag
    57241 tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg agattcctac ttccaaacgg
    57301 ctggcaacga tatcttttgc taacatcgtg ttgatgttga agtttttacc gtagtctctc
    57361 aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt tgttcacaaa tgtgatattt
    57421 gcatctttac caaacaattt tctcatttga ttggaaagtg cgtccacgtt atgttgcact
    57481 tgttccatcg tttgcaacac acgttctgtt ttgcggccgc ttgggtcgcc gatcgttcct
    57541 gttccgccgc caatcagaat atatggatga tggcctgcca attggaatct tttcatcatc
    57601 ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag ttggatcaac gccgcaataa
    57661 agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt cttcgtttgt ttgctgatta
    57721 atggcgtcgc gccaagttaa ttcatcaata atattcattt tactgacctc cgtgtagttt
    57781 ttttatgaaa gcaggaacct gctagcatat gtaattaatt atttcttcag gataggatag
    57841 gaaataaaaa aagtcccttg gcatataagc caagggacga aatctcgcgg taccacccaa
    57901 tttgtatgtc tagatatcca acatacctct cgaacattta acgctgtcgc gtggcaatca
    57961 ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg tactggtttg cagcgaccac
    58021 cagctttctg aaacattggc tttaacaact acttcgtttc gatcttcgtc ttgttattat
    58081 taatatgtgt ctatcataga gcgcaacttt ttctttgtca acagaaaaag gatatttttt
    58141 ttaaattcct cattttttct tttttgaatc cgctctaatt ccgaacattt tattttcaat
    58201 tattgttaaa agaaataact ttttctgtat tttttctgca atttatcgag aagtcacttt
    58261 actttgcctc ttattctttc ttcgttacaa taaggaatgg gacaagtaaa aaaatgaaaa
    58321 agcaagggac gaggtatatg gaaaaaaagc aaaaaattat tttaggagcc acttctgctt
    58381 taactatcgt tattttaatt ctaagtttgt tttttgtcat ccgatcatct acaaaaaaag
    58441 aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa agaaccgaca gatgataagc
    58501 aacaactagt tactcaagca aaaaatctgg ctcaaagcta cgattatgac caagcgattg
    58561 cgttattgga aaaagatagt aagaacggat ctactgaaac acaacagctt cttcaaacac
    58621 taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc tactcagatc tctcatgtct
    58681 ttttccacag cttgatcgtg gacccgcaaa aagccttcca ctctcaacag gcacaaggat
    58741 acaaagatta tatggtgact gttgaagaat tcaaccgttc gatcgaacaa ctttatcaaa
    58801 atgattttgt tttagttaat ttgaatgatt tgatccaaaa agacgaacaa ggaaatcttt
    58861 cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt ggttctttca caagatgatg
    58921 tcagctatta tgaatatatg gataattccg gttttcctag ccgattggtc gtatcaaata
    58981 acaatgaaat caaaaatgtc tataaagaga aagataaaga agaaatcggt gactttgaca
    59041 tggttcctct gatcgatgcc tttgtcaaga aacatcctga tttttcttat cgaggcgcaa
    59101 aaggtacctt ggccctgaca ggttacaacg gagttttagg ttatcgaaca tcaaaatctc
    59161 aatatggaga caatgaaaaa acaaaaaaag agattaaaga agctaaaaaa gtggcggaac
    59221 agttgaagaa agacggctgg agctttgctt cccatacatg gggtcacttg aatatgactc
    59281 aagcttcact agaagatgta aaaaaagaca atgaattgtg gcagcaagaa gttgcaccta
    59341 tcctaggaaa aacaaatatt ctgatttatc catttggtgc agacatcagc gactggcagc
    59401 cttattcagc agaaaatcaa aaatttgctt acttgaagag tcaaggtttc gatattttct
    59461 gtaatgtcga tgcttctaca ccagcttggg gacaattagg tacggatttc tatcgaaatg
    59521 ctcggatcaa tatcgatggc attcgttttc aatctgattt agacggaaaa aatcctattc
    59581 ttgatccatt catcaatgtc catgatgtct atgacaaaga agcacgcgaa tctgcttgat
    59641 tttacgtcat ttatgaacca aaaaagccga actgacattt tatcgtcagt ttcggctttt
    59701 ttatgcttta tttcttcttc ggtgcgattc ccttgatcag gacttctgtc cattctgctg
    59761 tatatggaag cagttttgcg tatatctccg gcttagaaat tccttctacc attgcttgaa
    59821 aatagaggat caagaactca tccgaatatt tcaaatccac ttttccttct ttccgccctc
    59881 gatggaaaag atcaagcatg atactgaaac tttcttgcgt atacgcatcc atcgcgtcag
    59941 aaaattcttt tttttctttt tttgtatagt atgtcatcaa atcgatataa aattgtttgt
    60001 tcactcgatt gagataacgg attttgtttt cactcatggc aatcagtgtt tcttcaaatg
    60061 gaagattttc cgcaatcaac gctttcgctt cttgccctaa atcattcata aatgcaaaaa
    60121 atacttcata aatcagccct tccttgctgc caaaatattt aaaaatcgtc gctttactta
    60181 cctgagcgtt ctcagctacc ttatccattg tcactccagc ggttcctatg tctgtgttca
    60241 tcaagtcaaa agctgcttgt aaaatctctt tctttttctc ttgtgctctc ttttcaaaac
    60301 cgttcatttg tagagcctcc cgtaatttta aacttttata atatatatag ttcaaattta
    60361 ttctgaggtt tattataact atctattgag aaagtatcaa gctagcaatt ccttgtttat
    60421 gaattcattg acagaaattt ataaaaagaa tattatgtac taaaataata aaaaaagttt
    60481 tataaaaagg tataaaacct ctttattaaa ctatttaatc ttgtttagta tatattttta
    60541 gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt cacacatttg aaaaagagct
    60601 ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt acattcaggt gaagtcgttg
    60661 gatttatcgg accaaatggt tctggaaaat ccacgacgat tcggacactt ttagggatta
    60721 taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga tgtatgggaa gatagtttat
    60781 ctatccatga acgtctttct tatgttccag gcgatatctc tttgtgggga aatttgactg
    60841 gaggagcgat catcgatctc ttcatgaagc ttcatggaaa agggagtgct caaaaaaaag
    60901 atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa agcaaaaaac tattcaaaag
    60961 gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt tgattcggat ctctatttat
    61021 ttgatgagcc tacttctggt ttagatcctt tgatggaaac gattttccaa gaagaagttg
    61081 aaaaattgaa agaacagggc aaatccatcc tactttcttc tcatattctc agtgaagtcg
    61141 agcgactagc ggataaagtc gtgatcatac gcgaaggaac actcgatgaa gaaggaacac
    61201 tcgatgaatt gcgtcatttg actcgttcga ccatcactat agaaacagaa gcagagaata
    61261 gtcacttagc acaattgaac ggtgtccatg actttgtgca aaaaggtcac ctcgctcaat
    61321 ttgctgctga taacgaagct ttcgatgtga ttttagctga agcgtccaaa ttaggtgtga
    61381 aaaaatttga atctattcca ccgactcttg aggatttatt catgagacat tatgaaggat
    61441 gaggaggaag cgaaatgact gataaatttt cacgctggtc cacccttttt tctcaaaacc
    61501 ttagccgtga ctggaaaaag atcctgatat ggctagtcgg tgtcactgct ttttctggtg
    61561 gttttgtccc tgcgtttgaa gaattgactt ccggacaagg attagctgga ttatacgaaa
    61621 ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac tccagcttcg aatgctgctg
    61681 agtatacttt aggagcgatg tatgcaaatg aaatgttgct tttttgcagt ttgtttgctg
    61741 ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa aaaagaagaa cttggtctga
    61801 ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa ctctttagct gtcatcgctg
    61861 aaagtattct gatcaatttg cttttagcaa tatcgatcag ctgtacgatg atttttttcc
    61921 aagcggattc gatcactgca gaaggtgctt ggctttttgg gctatctgta ggtagtatgg
    61981 ggattttggg gagtgccgtt gcactgtttg ctgcacaact gatgccaagt tcagccagtt
    62041 cgaatggtct gtctttagcg tttttaggtg gactttacct tctacgagca ataacagatg
    62101 tagctgattc ctccctttcg atgtggaatc ctttaggctg gtcttatttg acctatccat
    62161 ttacaactaa caactggatt cctttgcttt atttgttttt gttcagtcta atcttgataa
    62221 tcagttcatt tgttttagag gaacatcgag atttgaacac cggctatatc cccgaacgtg
    62281 aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg tggtttatta ttctatctaa
    62341 ataaagggat gacaatcagt tggcttatca cttttggttt gatgggggcg gcatacggct
    62401 ctatctacgg gaatatgcaa cagtttttag aaagtaacga cttaatgaaa cagatgttta
    62461 tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac gatcatggta gtcttgattt
    62521 gtctagctgc tattttacca attgctagca tcaatcgttt atttacagaa gaaacccacg
    62581 gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa ccaactttat tggaccaata
    62641 tgttactagc tattctattt gctatattgg caatcctgat tagttctggt gcactagggc
    62701 tttctgcttt ggcttcgatg aaggatgcga aagacatgga tctattgatg tttcttaaag
    62761 ccgggttcaa tttcctgcct gccgttttag tgtttatcgg aattagtggc tttctattcg
    62821 gatggcttcc tcgaatcggt aaacttgctt atatctactt agcttactcc tttgcactca
    62881 attactttgg cggaattttg gatttaccag aatggttttc caaaacagct gtccctagct
    62941 gggttccacg gatgccaaac gattcttttg atctttccgt gttccttacg ttatcatgta
    63001 tcagccttgc actgttcgtc cttggttcta ttggttatag gcgaagagac ttactagaag
    63061 gataataaaa aagcatgtac aatttcatgc tagcctccaa atctgggtca aaaatccaac
    63121 atttggaggt cattttttta tttacaagtc ttctaactgc tctttatcaa tgatccagac
    63181 ttctcgattc tttcttttta cataaccatt ctcctctaat aatttaaatt ttctagataa
    63241 agtttcgggg gtcgtaccga taaatgcagc aagttctttc attttcattg gcaggaaaaa
    63301 gtgatccttc cctgtcgctt tagctaagtc aagcagatag agagcgactc gttcttctac
    63361 tttttccatc atcaaaaaag ttgtctgctg ctgtactttt gttaatttct caacgttgat
    63421 tgctaaaagt ttcagactaa gggcgggata atgcagtaag agttccgaga aatctttttg
    63481 tctcaatatg caaatttccg ttttttctag tgcttcgcca aataaagact catttggaac
    63541 gcctagcaac tggctctctc cctcatatcc gcccggctct attactcgta aaagctgttc
    63601 ctttccgcta gcagataatt gatacacttt catactgccg gaggccacga tcactaattg
    63661 aggttctcca ttcggcgcaa gaatctgttc tcctttttcc acatagtgat gtttgacaag
    63721 tgcgtgtact ttttcttgat cttgctgtac taagtgattg aacaaaggaa caaatgaaac
    63781 acataaatga tcatgactca taatctctcc tccttctaaa cagctatttc taataaagaa
    63841 acataacttc ccttattcca actgataatt ttcttttatc atagcataaa cgtcaagcga
    63901 accagatacc agcaaataga gtggatttct ttttgtccct tgctttattt tccttctttt
    63961 gagaccttaa gtaattgatt cctatcaatt ttttaaatat ttactttttg aataatcaaa
    64021 aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt tcgcattgct tatttcgtgt
    64081 tgtctattga aatttttccg cacctagctt ttgatatagt ggtgctagtt cttgtaaggt
    64141 ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga tagaagaata gtttacccat
    64201 ttgaaaggtt cggtctctca tcgctttttt caactcttct tgtttctttg tatcggacaa
    64261 atagtcagac aaagctaagt ggtcgtcaag ttcatgttct ggttgcggcc atatgtaata
    64321 atccttgata tcgactgttt tgctccactc tttcagtatc gcaagcaact ggttatacgc
    64381 tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg tacatcaaat agatttggta
    64441 ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg tcttgacgag attcgcttcg
    64501 gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc gtccagcttt cgattttagg
    64561 tttgctcatg ccgtacatat caggcaaaag tgcagctgtc tggagctgaa tctctttcca
    64621 tttttgccag tgttctttat attctttctt gatttgttca atcttatctg ttggatggct
    64681 ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac aactgataat ctgattttcc
    64741 aagttccatt gtttcgcctc tttccgttat cttttgtatt ctacctgaat tttgcgatat
    64801 ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt cataagaaca gccaaacaaa
    64861 aaactgcgat gagcatcacc gcagttt
//
LOCUS       DADVXK010000006        64652 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.006, whole genome shotgun sequence.
ACCESSION   DADVXK010000006 DADVXK010000000
VERSION     DADVXK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.006"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            51..689
                     /locus_tag="KB909_000344"
     CDS             51..689
                     /locus_tag="KB909_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6836407.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(808..880)
                     /locus_tag="KB909_000345"
     tRNA            complement(808..880)
                     /locus_tag="KB909_000345"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Thr,seq:cgt)
     gene            1001..1243
                     /locus_tag="KB909_000346"
     CDS             1001..1243
                     /locus_tag="KB909_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836408.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(1382..2011)
                     /gene="upp"
                     /locus_tag="KB909_000347"
     CDS             complement(1382..2011)
                     /gene="upp"
                     /locus_tag="KB909_000347"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBB6836409.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(2145..3092)
                     /locus_tag="KB909_000348"
     CDS             complement(2145..3092)
                     /locus_tag="KB909_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6836410.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(3245..4489)
                     /locus_tag="KB909_000349"
     CDS             complement(3245..4489)
                     /locus_tag="KB909_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBB6836411.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(4680..5705)
                     /locus_tag="KB909_000350"
     CDS             complement(4680..5705)
                     /locus_tag="KB909_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBB6836412.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(5727..5906)
                     /locus_tag="KB909_000351"
     CDS             complement(5727..5906)
                     /locus_tag="KB909_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836413.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(5899..6738)
                     /gene="prmC"
                     /locus_tag="KB909_000352"
     CDS             complement(5899..6738)
                     /gene="prmC"
                     /locus_tag="KB909_000352"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBB6836414.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(6731..7804)
                     /gene="prfA"
                     /locus_tag="KB909_000353"
     CDS             complement(6731..7804)
                     /gene="prfA"
                     /locus_tag="KB909_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBB6836415.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(7807..8391)
                     /locus_tag="KB909_000354"
     CDS             complement(7807..8391)
                     /locus_tag="KB909_000354"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6836416.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(8497..8966)
                     /locus_tag="KB909_000355"
                     /pseudo
     CDS             complement(8497..8966)
                     /locus_tag="KB909_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            9072..9674
                     /locus_tag="KB909_000356"
     CDS             9072..9674
                     /locus_tag="KB909_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6836417.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(9778..10347)
                     /gene="lepB"
                     /locus_tag="KB909_000357"
     CDS             complement(9778..10347)
                     /gene="lepB"
                     /locus_tag="KB909_000357"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6836418.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(10577..11344)
                     /locus_tag="KB909_000358"
     CDS             complement(10577..11344)
                     /locus_tag="KB909_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836419.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            complement(11341..11820)
                     /locus_tag="KB909_000359"
     CDS             complement(11341..11820)
                     /locus_tag="KB909_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBB6836420.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(11945..12682)
                     /locus_tag="KB909_000360"
     CDS             complement(11945..12682)
                     /locus_tag="KB909_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBB6836421.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            12843..14243
                     /locus_tag="KB909_000361"
     CDS             12843..14243
                     /locus_tag="KB909_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBB6836422.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            14466..15818
                     /locus_tag="KB909_000362"
     CDS             14466..15818
                     /locus_tag="KB909_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBB6836423.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            15811..16509
                     /locus_tag="KB909_000363"
     CDS             15811..16509
                     /locus_tag="KB909_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBB6836424.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(16571..17722)
                     /locus_tag="KB909_000364"
     CDS             complement(16571..17722)
                     /locus_tag="KB909_000364"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBB6836425.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(17735..18172)
                     /locus_tag="KB909_000365"
     CDS             complement(17735..18172)
                     /locus_tag="KB909_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6836426.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(18187..19953)
                     /locus_tag="KB909_000366"
     CDS             complement(18187..19953)
                     /locus_tag="KB909_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBB6836427.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            20217..20894
                     /locus_tag="KB909_000367"
     CDS             20217..20894
                     /locus_tag="KB909_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836428.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            20897..22024
                     /locus_tag="KB909_000368"
     CDS             20897..22024
                     /locus_tag="KB909_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836429.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(22224..22664)
                     /locus_tag="KB909_000369"
     CDS             complement(22224..22664)
                     /locus_tag="KB909_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6836430.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(22675..24708)
                     /locus_tag="KB909_000370"
     CDS             complement(22675..24708)
                     /locus_tag="KB909_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6836431.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(24710..26413)
                     /locus_tag="KB909_000371"
     CDS             complement(24710..26413)
                     /locus_tag="KB909_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6836432.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(26507..27457)
                     /gene="manA"
                     /locus_tag="KB909_000372"
     CDS             complement(26507..27457)
                     /gene="manA"
                     /locus_tag="KB909_000372"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBB6836433.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(27496..28521)
                     /locus_tag="KB909_000373"
     CDS             complement(27496..28521)
                     /locus_tag="KB909_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6836434.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(28730..29599)
                     /locus_tag="KB909_000374"
     CDS             complement(28730..29599)
                     /locus_tag="KB909_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBB6836435.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(30303..32195)
                     /locus_tag="KB909_000375"
     CDS             complement(30303..32195)
                     /locus_tag="KB909_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836436.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(32192..33919)
                     /locus_tag="KB909_000376"
     CDS             complement(32192..33919)
                     /locus_tag="KB909_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836437.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(33935..34585)
                     /locus_tag="KB909_000377"
     CDS             complement(33935..34585)
                     /locus_tag="KB909_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6836438.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            34789..35085
                     /locus_tag="KB909_000378"
     CDS             34789..35085
                     /locus_tag="KB909_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6836439.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            35277..35897
                     /locus_tag="KB909_000379"
     CDS             35277..35897
                     /locus_tag="KB909_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBB6836440.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(35989..37155)
                     /locus_tag="KB909_000380"
     CDS             complement(35989..37155)
                     /locus_tag="KB909_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6836441.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(37167..37520)
                     /locus_tag="KB909_000381"
     CDS             complement(37167..37520)
                     /locus_tag="KB909_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6836442.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            37648..38670
                     /locus_tag="KB909_000382"
     CDS             37648..38670
                     /locus_tag="KB909_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBB6836443.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            38689..38850
                     /locus_tag="KB909_000383"
     CDS             38689..38850
                     /locus_tag="KB909_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836444.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(39109..39543)
                     /locus_tag="KB909_000384"
     CDS             complement(39109..39543)
                     /locus_tag="KB909_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836445.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(39653..41512)
                     /locus_tag="KB909_000385"
     CDS             complement(39653..41512)
                     /locus_tag="KB909_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6836446.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(41630..42790)
                     /locus_tag="KB909_000386"
     CDS             complement(41630..42790)
                     /locus_tag="KB909_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBB6836447.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(43097..44521)
                     /gene="araA"
                     /locus_tag="KB909_000387"
     CDS             complement(43097..44521)
                     /gene="araA"
                     /locus_tag="KB909_000387"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBB6836448.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(44537..45235)
                     /locus_tag="KB909_000388"
     CDS             complement(44537..45235)
                     /locus_tag="KB909_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6836449.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(45192..46853)
                     /locus_tag="KB909_000389"
     CDS             complement(45192..46853)
                     /locus_tag="KB909_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBB6836450.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            47071..48471
                     /locus_tag="KB909_000390"
     CDS             47071..48471
                     /locus_tag="KB909_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBB6836451.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(48723..49802)
                     /locus_tag="KB909_000391"
     CDS             complement(48723..49802)
                     /locus_tag="KB909_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6836452.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(49888..50847)
                     /locus_tag="KB909_000392"
     CDS             complement(49888..50847)
                     /locus_tag="KB909_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6836453.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(50859..52370)
                     /locus_tag="KB909_000393"
     CDS             complement(50859..52370)
                     /locus_tag="KB909_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6836454.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(52392..52955)
                     /locus_tag="KB909_000394"
     CDS             complement(52392..52955)
                     /locus_tag="KB909_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6836455.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(52961..53824)
                     /locus_tag="KB909_000395"
     CDS             complement(52961..53824)
                     /locus_tag="KB909_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6836456.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(53838..54734)
                     /locus_tag="KB909_000396"
     CDS             complement(53838..54734)
                     /locus_tag="KB909_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836457.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(54909..56198)
                     /locus_tag="KB909_000397"
     CDS             complement(54909..56198)
                     /locus_tag="KB909_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6836458.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(56170..57687)
                     /locus_tag="KB909_000398"
     CDS             complement(56170..57687)
                     /locus_tag="KB909_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6836459.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            57885..58775
                     /locus_tag="KB909_000399"
     CDS             57885..58775
                     /locus_tag="KB909_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBB6836460.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(58848..59672)
                     /gene="nadE"
                     /locus_tag="KB909_000400"
     CDS             complement(58848..59672)
                     /gene="nadE"
                     /locus_tag="KB909_000400"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBB6836461.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(59684..61156)
                     /locus_tag="KB909_000401"
     CDS             complement(59684..61156)
                     /locus_tag="KB909_000401"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBB6836462.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(61793..62155)
                     /locus_tag="KB909_000402"
     CDS             complement(61793..62155)
                     /locus_tag="KB909_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6836463.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            62378..63130
                     /locus_tag="KB909_000403"
     CDS             62378..63130
                     /locus_tag="KB909_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6836464.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(63270..64193)
                     /locus_tag="KB909_000404"
     CDS             complement(63270..64193)
                     /locus_tag="KB909_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6836465.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(64208..64480)
                     /locus_tag="KB909_000405"
     CDS             complement(64208..64480)
                     /locus_tag="KB909_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836466.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        18627 a        13306 c        11276 g        21443 t
ORIGIN      
        1 tcatgtatac tgactctatc ttcaaaaact gaatagtagg agttattatc atgaataaca
       61 ttttaggaaa aaaaatagaa cttaaaaaag ggatattggg cactattgtc gttgtactcg
      121 gtttgttagg gttgctattt gcgccatcca ttattagcat tttttcttta actatcactg
      181 gatttatagc atttacactt gtttttggta aaaaagatac gaaaaaaatg ttctcgaaac
      241 ctgtcgctcc tgtcaaaaat atagccaaat atttttttat caatgtagta atcagtgccg
      301 cagtctcggt atttttgcaa caaattttga aatggggttt aacaggcaat ccaataaatg
      361 aggctttcag cccgttatta tttattattt tgcctatcat gatacttgga gaagaattgt
      421 tctcagtgta ttttctcgct attttttcta gtaagttcag cattcctgtc gctagtttct
      481 tgtcagcaat catctttgga tttatccatt acagtactta tgataatgga aatattttac
      541 acactgtagc acacatcctt ttgatacaag gggtggcaag attgttattc aaccaagctg
      601 ccattaaaag caactcgatc attacaagtt gggcagttca tgtgatattt gatttcacag
      661 ctatattgct agtcgtttta ttctcctaaa tttttataga aataatacat gctctattgc
      721 taagaaagca tactttattt cctttaaaca aaaagacaga tgtatcaatg gattaaaaat
      781 ccttgatata tctgtcttct cttttaatgc cagctatagg gatcgaacct acgacctacg
      841 cgttacgagt gcgttgctct accaactgag ctaagctggc cttatccaaa agaaattata
      901 tactctattt ggctgattgt aaagagtccg atggaaaatt agtttaattt catgatattt
      961 ttcataaaac gtggtataat tgatgtgaaa ggcaggtttt atgaaaatgg caacttttgg
     1021 aaaatttgat acaactatcg taccatcgga aattggtgaa aaattcaaga tcaatactca
     1081 cgtaatgttc acaattcacg gcaagtcgca aactggaacg atttcaaagc aattgaaaaa
     1141 ttccgctgtt gttgagattg atgaaactgc agaaaatgcg aacttgatga cgcaaagtaa
     1201 gggtgtagta atcgttaact acaaagaact aaaaaagatt tgaatttgac catctctgca
     1261 tttttgggat ggttttttta tatgcaaacg aaagctgtga aaaagctgtt ctgcatcaaa
     1321 cgttaaaaat gaccaaaaaa ggatgtgaca aaagttgtgt cacacccttt ttcgtattta
     1381 cttattttgt accaaacaaa cggtcacccg catcccctag tccaggaacg atataaccat
     1441 gttcattcaa tttttcatct agagaagctg tatagatgtc aatatcagga tgcgcttctt
     1501 gcaaagcttt tactccctca ggtgctgcta ccaaacaaac aaatttaatg ttcgacgcgc
     1561 cacgttcttt caatgcatcg attgccatga ttgctgatcc gcctgttgcc aacattggat
     1621 ctactacaaa caactgacgt gcatcaatgt cttctggaag tttgacgaaa tattcatgtg
     1681 gttccaatgt ttcttcatct cgataaagac cgatatgtcc cactttagca gctggaatca
     1741 attccaagat accgtcaacc attccaatac ctgcgcgcaa gattggaata atcgctactt
     1801 ttttaccaga caacgttttt tgtgttgttt cagtgatcgg tgtttcgatc acgatgtctt
     1861 ccaatggcat atcccgtgat acttcatatg ccatcaacat agcgatttca tcgactactt
     1921 cacgaaaaac ctttgttccg cagtttttgt cccgaataat agttagtttg tgttgaatca
     1981 atggatgatc gatcacttga aatttgccca ttttttaagc tctcctttgt tctgtcgttt
     2041 ctttttaatt gtaaaacaaa atcaagtgat tgactagtca aactcgccat ttttcctaag
     2101 aaaatccgtt tttgaaaaga agttttcctg cggacaagca aagcttattc ttttttcttg
     2161 atccaagaag tagataatgc cattgctgca cgcgttgcct ttgtctgatc catagcattt
     2221 accatgacaa aatcatggat gattccttgg aagcgtactt gtgtaacagg aacccctgca
     2281 tcacgaagtt tgcgcgcata agcctcacct tcatctctta atacatccgc ttctcccgtt
     2341 aaaatcattg ctgaaggaag atcatttagt tcatttatat ttgctctcaa aggcgaagct
     2401 gtgatttcag cacgctcttc ttcattcgtc gtatattggt cccaaaacca catcattcct
     2461 tctcttgtca aaaaatagtt ttctccgaat tcatgatagg aatctgtatc aaaatcagcg
     2521 tttgtgactg gataatacag caattgcttg gatattggga ggccctttcg ttcttttgtt
     2581 aagatcgtca tgactgtagc catgttacca cctactgaat ctcctgcaac gattagattc
     2641 tcgagatcca gattttttga cttggctaat ttattcagct gttgcaacac agcataattt
     2701 tgttcaattg ctgttggata ttttgcttct ggtgatcgac tatattctgg aaagacaacg
     2761 acggaattcg tacgaaccgc aagttctctg atcaatttat catgggtttg agcactgcca
     2821 aaaacccagc ctgctccatg aatataaaaa ataactggta atttatccat attcccttct
     2881 ggtcgtacga gacgaatatt gagttttccc cattcgccag tatccaccat caagtcttca
     2941 atatcgacgg aatatttgtt cacaggtgat tcttgtactt cttctagtaa aactcttcct
     3001 tcttccggtg ctagttcata gatacgcgga tgaggcgcat ttgcatcact gaatgctact
     3061 gcttcctttt ctaacgagat acgatcagtc atgacttttc ctccctgaga tttagtgtga
     3121 agactaaaat tacacctcat atactagaga gcatcaccga tattgtcaaa gaatccgttt
     3181 tcccaaaaaa taaacagaaa agcccaacat tgaacttttc tgtttactaa tggaatttaa
     3241 atttttattt tttatgcaac ggaaattttt cagttaattc gcgtacacct gttttgactt
     3301 cgtctagttg agcgttatca tcttttgctt gtaatgcttt gacaactagt tcagccactt
     3361 ttacagcatc ttcttctttg aacccgcgag tagtgattgc tggcgtgccg attcgaatac
     3421 cgcttgtttt gaatggactt agtgtttcaa aaggaatcga gtttttattt acagtgatat
     3481 tcacactgtc caaaatgctc tctgcttctt ttccatttat acctaactcg cgaacatcga
     3541 tcaacatcag atgattatct gtcgcccctg aaatgactct ggttccaatt gcttgattga
     3601 aaactttgac cattgctttt gcattggcga tgatttgttc actatattct ttaaatgcag
     3661 gatctaatgc ttctttgaat gctactgctt tacccgcaat cacatgctct agagggccgc
     3721 cttgaatacc aggaaatacc gcactattta ttttttttgc taatgcttca tcgtttgtca
     3781 aaatcatgcc gcctcgaggg ccacgcaatg ttttatgagt ggtagtcgtt gtgatatctg
     3841 cataaggaac tggattagga tgaagtcctg ctgctactaa tcctgcgata tgtgccatat
     3901 ctaccatcag ttttgcgcct acttcatctg cgatttctct gaatttcgca aagtcgatcg
     3961 ttcgtccgta agcactggca cctgctacga tcaattttgg ttgatgtttt ctagctaaaa
     4021 tacgtaccac attataatca ataacttctg ttgtcggatc aacaccgtaa gcaacaaagt
     4081 gataggtttt gccactgaag ttgactggtg atccatgtgt tagatgtccg cctgcggaaa
     4141 gatccattcc taagatcgtg tcccctggtt ctaccaaagc gagataagca gccgtgttgg
     4201 cttgagagcc ggagtgaggc tggacgttcg caaatttcgc tccgaataat tcttttgcac
     4261 ggtcaatcgc taaattttca acgatatcga caaattcaca cccaccataa tagcgatgcc
     4321 ctggataacc ttctgcgtat ttatttgtca agatacttcc ttgtgcagcc atcactgctt
     4381 cggagacaaa gttttcagag gcaatcagct ccaaattatg ttcttgtctt tcttcttctt
     4441 tggcgatcgc agcccaaaga tcagggtcaa acgttttgta atctaccaca aacaacagct
     4501 cctttttatt ttcctacaat tttattttcc tacaatttta tttttcccat caaaaacaaa
     4561 ttgccaaata ttcgtatctc ttctattacg attagttacg cttagttttt cgttcactga
     4621 tagaagattt acttgatagc attgtatcat actaaaagaa tgcgacaata accaattgat
     4681 catttttcaa aataattttg tcctgctgct tttttcaagc gattcatgta agcattcccc
     4741 aatccagttt ctggatacac ttgtacaaaa atcaaatcta atccaagtgt tggttcatct
     4801 aatcctctta gacctgcaaa caatccttta gccgccgctt ctactgagtt gtcgttatac
     4861 atataaacag ctgcagtatc tgtccgcact tgatccgcaa tttcggggct tgctatgaca
     4921 cctgcacgga tcttcttatt ttttgcccat tgaactgcag ttgaccaatc gccatctctg
     4981 accatcagaa cacgtgtatc gggtgagtag tgtttgtatt tcatcccagg ggcttttggt
     5041 gtttcatttt cttttacaag atgctgatca atagcaacag gagattcgat gactgcttcg
     5101 atttgttctt tcgttactgc acctggtcgt aaaatcatag gcatggctgt tggatcactt
     5161 aaatcaagaa cagtggattc tacaccaatt cgcgtagctc catcatcaat aatcccggta
     5221 atttttcctt gtagatcatg atatacatga tctgcagtcg ttggacttgg ttttcccgac
     5281 gtatttgcac ttggaccgac aagcggaaca ccggaaagtt cgattacttc tagtgttttt
     5341 ttgttatccg gtatacgaaa tgcagctgtg gataatcctc ccgtcacaac tgagggcaaa
     5401 gtgtcttttt tgatcttaaa tatcaaagtt aatggtccag gccagaagtt cttcacaatc
     5461 ttctctgctg ccggatgaaa gttgtccaca tactctttta cttgttcaaa agaggcgaca
     5521 tggacgatta atggattatc ttgcggtctc ccttttacag aaaacacttt cttgacagcg
     5581 tttggtaaaa gagcgttggc gcccaatccg tatactgttt cggtaggaaa agcaacaagt
     5641 tctccttctt tcagtgcttc ggctgcctct tgcaattctg tttcatcata tcgtttcgtt
     5701 tccacagttt atccacaacc cctttttcat acattcttat tttgtctgag tttatcctca
     5761 agttttccac tgtttgtgga taatctattt gtcaatagtg gataaacttg ttgataaacc
     5821 aaaaagtcgt ttacatcctt gtcaaataag tgttttttta taataaaaaa acaaataaaa
     5881 aatttttcat ccacaacttc aaccataaac ttggatcatt cgttcattgc caaaaagatc
     5941 cttttttatc gccacttttt tatctggaaa tgcttgctga aatatttttt ttactgcttc
     6001 accttggcga aatccgattt ctaaaaaaat ctttccattt gattttagta cgcttggtgc
     6061 ttcaactgct attttttcat aaatagctaa tccatcgttc tcagcaaaaa gggccatttt
     6121 aggttcgaat gaccggacac tttcatccat cagttcccat tcattccgac tgatgtacgg
     6181 cggattagaa ataatcacat caaattgctg atccattact ggtcctaatg tatctccatg
     6241 ataaaaactg attttcgttc cttctttctg agcattttct ttcgctactt ctaatgcttc
     6301 ttctgaaaga tccacagcag atatatgcca attttttctt gctgctttca aactaatagc
     6361 aattgctcca gtccctgtcc caatatctat cacttctaac ggtacaccag gcgtctcgtc
     6421 taaacaccat tcgactaact cctctgtttc tggtcgaggg atcagtgttg cttcagttac
     6481 ctttaaccga tgatcataaa aatctgcata tcctagcaaa tactgaggtg gatgatctgc
     6541 aagcagaagt cgcagatcgg tttcgatcaa ccgctgttct tcttctgaaa tctcttcgtt
     6601 catatgaagg agccaatcaa gttttttcca ttgttttcgt tccaaaaata aaaattggat
     6661 actatatgct tctttcccat gatcctctaa aaaagaagaa gcccgtgaca ggacttctcg
     6721 ataggtcatt ttacccattt tgcatagctt ccagttttga tgtttgatca tacatgatca
     6781 atgcatcaac gatctcatct aatttccctg ctaaaatctg atctaatttt tggatagtta
     6841 atccgatacg atgatcagtc acacgatttt gcgggaaatt atacgtccgg atccgttctg
     6901 aacgatcccc agttccgact gctgattttc gattggcatc atactcgctt tgtgcttctt
     6961 gctggatctt atcgtacaca cgagcacgca agattttcat tgctttttca cggttcttga
     7021 tttgagaacg ttcatcttgc atagcaacaa cgatccctgt tggtaagtga gtcaaacgta
     7081 cagcagatgc tgttttattg acgtgctgtc cgccagcacc tgaagcatga tagatatctg
     7141 tacggatatc tttgtcttca atatcgatct ctacttcttc agcttctggc atcacgacaa
     7201 ctgttgcggt ggaagtatgg atacgccctt gcgattcagt tgaaggaaca cgctggacgc
     7261 ggtgcgcacc actttcatat tttaatttcg aatatacgtt gtctccggtg atcatcatga
     7321 tcacttcttt atatccaccg attccggtaa cgttagcttc catcacttct gttttccagc
     7381 cttgtgcttc agcatacttt tggtacatat tgaaaagatc gccagcgaat aatgctgctt
     7441 cgtctccgcc tgctgctcca cggatttcca tgatgatatt tttatcgtca tttggatctt
     7501 ttggtaaaag caagatcttg attttttctt ctaagacttc tttttctttt tttaattcag
     7561 ataattcttc ttttgctagt tcagccattt catcatccag tttttcacca agcagttctt
     7621 ctgtatcggt gattccttgt actacttctt tataacgacg ataaacttcg actgtttcgc
     7681 gcgtgtttgc ttcttctttt gaaagctgca taaaacgctt tgtatcagaa atcacttctg
     7741 ggtcacttaa aagttctcca agctcttcat aacggtcttc aattgcttgt aattgatcgt
     7801 acatgcttat tctccttctg taatcattga tgggtgaaag taatgttttc gacaaacggg
     7861 gtaataagct tcatttccgc caatttgcac ttgatcgcct tcataaacag ggtttccatc
     7921 aatataatgt aaattcatga ttgctttttt gtggcagaac caacagattg ttttcatttc
     7981 ttcgattttg tctgcataaa gcaataaata ttttgatcct tcaaataact cgtttcgaaa
     8041 atcatttttc aaaccaaatg ccataaccgg aatatccaat tcgtccacaa ttctcgtaaa
     8101 agcaatgaca tgtttctttt ttaagaattg cgcttcatcg atcagcacac aatagggttt
     8161 gctttccatt ttctgaatta cgtcaaatac gtctgtttct tcaaatatcg gcatcgcatt
     8221 acgtttcagt ccgattcggc ttgaaacaac gcctaaacca tctcttgtat caataccgct
     8281 tgtcattaag acaactggct tattttgttc ttcataatta tgtgcgactt ttaggatctc
     8341 gatcgtcttg ccgctattca ttgcgccata cttaaaaaat agttgtgcca tgctcttttt
     8401 caccttccag tttgttccta tggtattata cttgattttc agcatttttt acagtgagaa
     8461 ttttcatcaa gcacagatta gtattaaatc tattgctcac ttttgttcca attttttgac
     8521 aagaactaaa catgggttcc attcatccca taaatttgga aaaacttcca accttgaaaa
     8581 tcctaatgat tcgtagaaac aaatagtttg atcatatata gagtagtgcc cctcgtctac
     8641 agtcttcact tgcaaatatt tgtaatgttt tgctgcgtaa ccttctgctt ctttaaaaag
     8701 ttttgttcct aatccttggt gatgatagtc tttttttatt cccatacaat agaatagatt
     8761 tcggcagtat cttcacttgt ctgtgaaaga gtgataaagc ctaaatattc ttcttttctt
     8821 ttttcacacc ataaaggtag tttacttgat tcctcgatat atttttccgt tgattcagga
     8881 agcccaaacc actcaggcaa gtctagtaat atttctcgga cacactttcc tttttcctct
     8941 ctatctttta caaacgatat cggcatattc tttctagatt ctcccttttt gaattgagta
     9001 tagcatgctt tctttctttt cacgtgctat aataagttaa aatttcaaag ttttacgtaa
     9061 ggagctattt gatgacaaaa aatatttttg attccatcgc taaccattat gattcccctg
     9121 accgtcaagc attagccaag attattcgcg aagaactaac tacttatcta ccgcgcgaca
     9181 gccaccaaaa agtcctgctg gattacggag gcggaactgg gcttgttagt ttaccgcttg
     9241 cggaaagatt caaagaactg atcattgccg atgcttcaga aactatgctg aaaatggcag
     9301 aagaaaagat ccaagcagca gatctgaaaa atgtccgaac gatccacgct gatgcttctg
     9361 tcgaatttcc tgctgtccaa gctaatctca tccttctatc acttgtactt ttacacattc
     9421 ctgatacgga gaatattctt acaaaacttt atgaaatttt agctcctggc ggtcaattga
     9481 tcatcgtaga ctttgacaag aatgaacaaa ttagtcatcc gaaagtccat aatggcttta
     9541 gccaagaaga attgaataat cgattggaaa aaacgggctt tgtctctgct actagtcata
     9601 ccttccatcg tggggaaaag ctatttatga acaaaaacgc ttcgcttttc ttatccatca
     9661 gccaaaaagc ttaaaatgag attgcaaaaa aagtgagcaa ctccaagaaa taagaaggaa
     9721 ttttcggaaa aagaagctgt gacaaaaaac atgtcacagc ttctttttat tttttcatca
     9781 catgatttta atttctgaaa gaggccaata acggaaaaca acttttcctt ggatcatatc
     9841 tttgtcgact aacccaaaca ttcggctgtc ttttgaaatc aagcggttat cgcctagaac
     9901 aagatacttt ccttttggca cagtatattc aaagtcactc gtaaaggtgg atgaactttc
     9961 tgcttgtgct tggaatcctg agctataagc atattctcct tgtaacttat cttctgaaaa
    10021 ttcttttttg aactcatcca gataaggttc atcatacttt ttgccattaa tggtcaactg
    10081 gtcattttcc atcttgactg tatctccagg cataccgatg atccgtttaa caatcatccg
    10141 ttcttcatcc cccggttcct ttgtagtaat aatatccatt cgttcatagt ttgagatctt
    10201 agatgaaatc aatcgttgtc catcacttaa tgtagggtcc atcgaatgcc cgtttacagt
    10261 aactggtgta aacacgtaca ctctagctaa taaaatagcc gctaatacaa ggatcaaaat
    10321 cccccaattt ttcaaaaatt ctttcacagc ttacctccta cttgtatttt cctcgttatt
    10381 tattacgttt tttcacaata cttcgttgta ctttctttat tctacaatgt ttataaatga
    10441 aaggaaagaa taagtgatgt gttcgtctta tctttctcgt tatataaaaa aggaacgtga
    10501 caaaagacgt gtcacatccc ccttattccg aataaacgtt tttatcgcaa ccactgatac
    10561 acggcgtttc atcacattat gaatgtcttc ttctttggct acgactataa accactggtt
    10621 cttcctgcga ctgtgccttt tttgcaatca atttcagacg ataaggctca tgatagcgta
    10681 acccgtcttt gacaaaatca ccgccgacga tgaacaatcc gacaggttcc aatgtgtctt
    10741 ctgttgagtc aagtcgaatg gtccctactt tttccatgtc cgagtagctt cgtccaatat
    10801 ttagaacata ctctttctct cctgttttct tgacatagta ataaggatac aatgtatttc
    10861 tatcgaccag aaatccatcc atgcgaccga gttcatttgt tttgatctca ccatttccaa
    10921 tcaaataccg catattctcg gctaatttca attgataatc ttcgtcataa gaaaccatga
    10981 cctcttgtgt attcacttta tcgatcgaat ttccattatc tatcgattct tctgtctgga
    11041 tgttgaacgc ttcatcaggt aaatacttca caaaaagctg agtgacatcg gctttcgtgt
    11101 ttttatctaa aaagtaataa aatacattta aaacagtaaa ataaacaagc actagaaatg
    11161 caagtccata taagaaaaat tgaagatagt tttggttttg ccaaagtcca taaacaattc
    11221 tcaataaata aagcgtggga atcacactta aaatcgtata tccacggtta agatatttag
    11281 gactgatgtc taaatagcca aggaatttat gcaccccgtt gataaggtct agtaaaaatg
    11341 tcattgagaa tcacctgctt gctggttata cgtttgggta tttcctgaat cttggttttg
    11401 ctgtgctgta cgtgctgcat catcattttg cgtgttatca tctacagtcg tactgcttgg
    11461 tatcgtttcg gagctagcac ttgtatccgg acttgtactt ggattggttg aatccgatgg
    11521 agtgccatct ggtaccgtat tacttgtttc gcttgagctg tcagttgtat atgtctcatc
    11581 atacgacgaa ctagttgttg tatcgtccca tgtacttgtc gtagtggttt cattcaaact
    11641 ttccgttgtt gttggttcag atgtcgagac tgaagtagtt ggtgttgttt cttctacagt
    11701 actagaactt gaacttggtg cacggtagct ggaactattc acaatacctg tagtagtcgc
    11761 gacaatcgtc gagattgtta atacagcgat tggcttcaaa ataggtgcta cttttcgcat
    11821 cttatctctt ccttcattga aatttattct tgtttcctta ctttactacg gacaaattat
    11881 acagtctacc ttatttctac cataaattct ttattttttt cttacgtttt tccgaaagat
    11941 ttctttaatt ttcctcaaaa actacggttg atgtttttaa gtaagctttt gcttcccgat
    12001 tgatttcttt cagatcgcat ccttgctgct tggcagcgaa cacgcaacca caataacatt
    12061 ggcgataaat atcatactct ttgcacattt gcaaagagcg ttcatagcct ttgtttttct
    12121 tgaaatcact tggcaagtat tgtgtcccgt aaatcttttg gatatccatt ccgatctgat
    12181 tgatcaaagc tgcatttttc tttggcgaga tggtcagggc acttccaaag taatcgtatc
    12241 ctagttcttg cgctttttgc gcaacaagat ctaatcgcat attgaagcat gcactgcagc
    12301 gagcaccacc ttctttttcg ttttcaagat ggtttgttaa aaccattttg gtgaattcat
    12361 ttggacggta ttcatcaacg attagcgcaa catgatggtc agttttctca ttaaattggt
    12421 ctacaaatcg tttttgttca tgtaatcttc gcaaatactc acttttagga tgaatattcg
    12481 aatttgaaaa aaataacgtg atctctgcat attgagacat gaattccaat gtgtgcgtac
    12541 tgcaaggagc acagcatgta tgtattaata tcttaggctt tacttcttct ttctcccatt
    12601 gcatgatcat ttttttcaga actgtatcat aatttatttt ttgatttttc attttttcta
    12661 cgatttgttg agcattaatc aatttgttat tcctcctcct tcttttttct aggattttcc
    12721 ttattataag ccatttctat tttaatcgaa agctgtattg ttatctgttt gataatttct
    12781 ttgagtattc ctaattcccc ttgtatactg gtagaaacga ctattgtcag gaggatagta
    12841 ctgtgcatgt tgatttattc tttcgaaggc tgcagcggcg aggacagaag tttgctgcca
    12901 atcatttctc atcgatccaa atcatcgttt tttattatat attgatgacg gtcttatcac
    12961 tcgttctatt ttatatgccg atttttcgcg aaccagatag ccatgtttct tttgtggaca
    13021 tgctgttcat ggcaatcagt acagtgagtg tgactggact atcgactttt gatatcaatt
    13081 ctgtgttcaa tgataacggt attatactgc tggaaatatt atttcaagtt ggtggtttgg
    13141 ggatcatgat gatttctact gcttttgtca ttttttctaa acgacggatc acactgaaac
    13201 agcgacagct gatcatgacg gatatgaatc aaccgcgttt gtctggtatc gtccgactga
    13261 ttcggatcac ttttgctatt ttaatctggt ttcaattact ttttgggaca ttcttttcta
    13321 tttattttta ttacagaggc tattttgatc gttggcgtga tgccgttttt tacggttttt
    13381 atcaggcgat atcggctgtc acgaactctg ggtttgacgt cactggggat tccatcaagc
    13441 cctttgcaca tgactatttt ttcttgatcc tgatcatgtt tttgattttt gtcggaggaa
    13501 ttggttttcc tgtattgatg gagtgccggg aatggctatt atacaaacgt tccaatgcga
    13561 agcttccgtt tcgtttttcc ttgtttacca aattagctgt gttagctttt gttatcttgt
    13621 ttgtttcggg aactgtcttg atttatctat tggaaaagga ccatttattc caagattcca
    13681 atatgagtgt caaatggatc aattcgatgt tttattcgat tacgactcgt aatgctggtc
    13741 tgcagattca cgatttgggt gattttcaaa tcacaacact gatcattttt tctttactga
    13801 tgtttatcgg atgcagtcct agttctgtag gcggcgggat tcgaacaact actgtagcaa
    13861 tcatcggttt gtatctatat tccttcctca aaagtgaaga taacatcaat atttttggac
    13921 ggagaatcga tcaagatgat gtgcgaaaat cagtcgttgt ctttatgctt tctcttggta
    13981 tgtgtttctt ttgtatcgtt tttttatctg ctacagaaga acaaacgctg atctcgatca
    14041 tcatcgaagt aacttctgcg tttggaacaa ctggtttatc tttagggatt accggagact
    14101 tgtctgttgt gggcaaaatc acgattgcta cactgatgtt tattgggcgg atcggaatgc
    14161 tatatacatt gatgttattc gtgccaaaag aaacacgaga tctaggctat gaatatccaa
    14221 gcgagaaaat tattatcggt taaaatggga atataggtaa gagggaataa taaaatcaca
    14281 gcagcttgaa acaatcattt tgtttcaagc tgtttttttg ttaaatcatg cgattttgtc
    14341 cgatttcatg cactttcagc cgtaaccttt tcttaagaat aagaaaagca atttaacctt
    14401 tttttcaaca tatggtatga ttagttgaat ttattcgtca gcaaatcgtt tttggaggtt
    14461 acataatggg aatacgcagt cattttgcga ttgcagttgg aaaaacgtcg caatgggcat
    14521 taaaaacttt ttttaaaggc ggatcaagtt taccaggtaa actagcgctg aaagtcgatc
    14581 cacatatact agatagtttg gcaaaagact accaagtcgt cgttgtcacc ggaacaaacg
    14641 gtaaaacatt gactaccgct ttaacagtca atattttgcg ccagcaattc gatgaagttc
    14701 taaccaaccc tactggtgcg aatatggtac agggaattgt atcgactttc ttgcaggcaa
    14761 aaccaaaaaa aggacagaaa aagtttgctg tcctagaaat agatgaagca agtttgagca
    14821 aagtcacaga atatatgaaa ccagaactgt tcttatttac aaatattttc cgtgatcaaa
    14881 tggatcggta tggagaaatc tatacgacct ataaaatgat tgtagacggt gccgcaaagt
    14941 caccaaatgc aacgattatc agtaacggtg attcaccaat cttcaattct atcgaaacag
    15001 tcaatcctag aaaatattat ggctttgacc atgaagaaga tcgtgaacaa atggctcatt
    15061 acaatacaga cggtgtctta tgtccaaatt gtcatcacat cttgcattat aaaatgatca
    15121 cttatgcaaa cttagggaaa tattactgtc caaattgtga cttcaaacgt cctgaattgg
    15181 attatcgatt aactgatatg gtacggatgg acaatgtgtc agcagatttc gtgatcgatg
    15241 gtcatgaata cggaatcgaa gttggcggta tgtataatgt ctacaatgct ttagcagcta
    15301 ctgcagtggc agagtacttc aatgtcgatc ctgataaaat caaacaaggt ttaggatatg
    15361 acgagaaagt attcggccga caagaagtca tcaatatcaa tgggaaaaaa tgtacattag
    15421 tacttgtcaa aaatcctgta ggtatcaatc aagtaatcga tatgattggt ctagctcctt
    15481 atccattttc tttagtggct ttattaaatg ccaattacgc agacggaatc gatgtcagct
    15541 ggatttggga tggtaatttt gaaaactttg ccgatatgga tatcccagct gttatttctg
    15601 gaggagaccg tcatacagat atgactttac gtctaaaagt tgccgggatt ccagaaaata
    15661 aattgacaga aacaaaagaa ttaccagaag taatcgaaaa aatcaaagaa ttgccaactg
    15721 agcatgtcta tattttagct acttacactg ctgtattgca gcttcgtaaa gaactagctg
    15781 ctcaaggatt tatcaaagga ggaatgaacc gtggctaatt atgaactcaa tatcgcccac
    15841 ctttatggaa atttgatgaa cacatatggt gataacggaa accttttgat gttgaaatat
    15901 atagcagaaa aaatgggggt ttcttgccat acggagatcg ttagtataca tgaacctttt
    15961 gatgctgata aatatgactt ggttttcttt ggcggtggtc aagactttga gcaattaatc
    16021 atttcaaaag acatccagaa aaagaaagat tctttgatca actatatcga aaatgatggc
    16081 gtcatgttag ccatttgtgg tggctaccaa ttgctaggtc actactacat gggagctaat
    16141 ggagaaaaga tccaaggaat cagtgcactg gatcactaca cgttaagtca ggaaaataac
    16201 cggtttatcg gtgatatcgt tatccataac gaagaattca atgaaactta ttatggattt
    16261 gaaaaccaca atggtcggac tttcttaggt gaaggtgaac gacctttggg gaaagtggta
    16321 caaggtcaag gaaataatgg tgaagaccaa tctgaaggtg tcatttaccg aaatgtcttc
    16381 ggttcttatt tccatggacc tatccttgca agaaatgaga acctggcagc tcgtttgatc
    16441 cgcctagctt tagaacaacg ttacggtaaa gaattggatc tgccctatct tgaaggacaa
    16501 acagcctagt tattcgaaaa aggggaatgt gacaaaaatt tcgtcacatt cccctttttc
    16561 gtatcctatt ttaagcgact tgcttggcat aacggttcac gttttgcttg atattcccga
    16621 ttgttttcgg atcattgatt cctgtgactt cttgaatcaa ttgttccaag ttttcatgga
    16681 tcttcatttc atgcaattga cggctttgtt catcttcagg atcatagtaa ttaaaaataa
    16741 tccccattgt tgccgtcaaa tgtgggcaag tcaagttatg ttcttgtagt tctctcactg
    16801 gacgtgtaaa tctttcttga taacctaact tacgtaatgg tgtccgagcg acacgtgtga
    16861 tcgcatcaga gatatttttg ttttggaagc gatgaatgat tttttcaata tacgcatgat
    16921 gctgctctgc atcaaacccc catttggcaa tcagcaaact tcctgtttcc tgcaaaactg
    16981 attttaattg tgccacaact aacgcatctt gcattgcttc atcaatggtc tggtaaccta
    17041 acaaggcacc tgtataagcg acagtcgcat gaccagtatt gacactaaat agtttgcgtt
    17101 cgatatatgg ttctagatca tctacatata aaaccccttt taattggatt tttttatttt
    17161 ttctttggct atcgtcaatg acccattctt tgaaaggttc cacttggacg aataaaggat
    17221 cttcatggtg ttgtaatggg acgattcgat cgactgctgc atttggaaag ccgatatatt
    17281 tgtcagtaaa tgatgtttcc ggaagatatt tatacacttc tttttctaga aatgctgaac
    17341 cgccaatcat attttcacag gcaatgatat ctaaagatgt tgtgcttcct tccttttctc
    17401 tttcttggat accttttgca atcaactcag caataaaagg taagatattc gggccaatgg
    17461 cggtagtaac taaatctgct tcagcgattt cttggattac tttttctgga tttgtttgat
    17521 tgttgattcc tttgacattt tttacagtga ttttttcttt tgattcatct gctaattcga
    17581 tttcgtattc ttttctttca tttaaagcat caatgatcgt gtgattcaca tctacgaaag
    17641 taatctcaaa tccattagct gccaaaacct ctccaataaa tcctcgaccg atatttcctg
    17701 caccaaaatg tactgctctc atttttctct ctccttaagc aattgctaga ttttccgtta
    17761 cttcttcttt gctgagcgcg tctgctagct ggacaacatt gtccatatca ctgcaataaa
    17821 gtgcgatttg ctgtacaagt tgcaaatgct catctccgac tcctgcaata ccgaacaaaa
    17881 cagtcgcaat cttttcttct tcttcggtac caaaatctac accatctggt acttgaacga
    17941 cacagatgcc ggattttttc acatattttt ttgcttcatc tgttccatga ggaatcgcga
    18001 taaaattccc catataaaca gataacattt tgtctctatc taccatggca tcgatatatt
    18061 cctcatcaac gcaccctgct tctacaagca tctgaccgca atagcggatc gcttcttctt
    18121 tggttttaaa agatcgattg agctcgatca tgtcgaatgg caaactttgc atgctgtttt
    18181 cctcccttaa gctgtctgtt tcaaatattg tgcaatcgat tcgtattttt gcggattgac
    18241 catgctgttg actgataaat gaatggattg aggtgcagcc atctgtactt tttccgctaa
    18301 actttctttg gctacgatca gtgaatcagg ttcatctttt aaatcttgga tattgacttt
    18361 tcttaacggg atagttaaat ggttcttgtc taatatatct ttgagcacgg tcatccccat
    18421 tgttgctgat ccggaacgat catcgtggac aagtagaatc tctttgattt gtttgatgtt
    18481 tgctgaaaga aactcttctg ctggctcatt ctcaatttca gaaactgatg ttttctgctt
    18541 gctgcttaat tcttgaatga tttcatcata tcgaggtgaa ttcaaaaagt tttctactga
    18601 gacaaaacgc gcgctcggtg ctttttgttt tgctctttct tgtagttcga cctgagtaac
    18661 gatcaatgta ttcgagtcat ctgtcagttg gctgattgct tgattggtca ccgtttgagg
    18721 caagtctgct tcctgtactt tttttctcaa gatcgaagcg cccatcgcac ttgatcccat
    18781 tcctgcatca caagcaaaaa tgattttttg tacgccagag aatgtagctc cttgaggaat
    18841 accttgggca cctttggaag cttgcttagc tgcctttgtc tcttgaacag atttttcgaa
    18901 gtcttcattt gtatctttcg catccgcttt caaaattact gcagaaatac caaacgaaac
    18961 agctgcggca acaatcacgc ccaaaataac aggaaggtaa gaattgaacg gtgtcatcgc
    19021 tagaatcgca atgatcgacc ctggagaagc tggcgctctt agtccagcat ccatcaattg
    19081 gaaaatgaaa cttcctgaca ttcctccgcc tataactgat aagaataata acggtttcat
    19141 cataacgtaa ggaaaataga tttcatggat cccgcctaaa aagtgaatga tcatggctcc
    19201 tggtgctgaa gattttgctg ctcctttgcc aaacaaagta aaagcaagta atacgccaag
    19261 tcctggacca ggatttgctt caagcaagaa tagaatagat tttccagcct ctgctacttg
    19321 ttcagttccc aatggtgtca aaatcccatg attgattgca ttattcaaaa ataagatttt
    19381 tgctggttca ataaaaatac ttgtcaatgg aatcaaatgg gcagataaaa tgatctctac
    19441 accttttgcc attgcttgag tcaatgcatc gacaactgga ccaatcgcag aaaaacctaa
    19501 taacgctaat ccaaaaccga taagacctgc tgaaaaatta ttgactagca tttcaaaacc
    19561 ggatttgatc cgtttttgga atagctgatc aaatttcttg atggcatatc caccaagagg
    19621 tcccatgatc atcgcgccta gcatcattgg aatatctgtt ccgacaatca cacccatcgt
    19681 tgcaattgcc ccaacaactg atccgcggtc accagcaatt acttttccgc cagtataacc
    19741 gatcaataaa ggaatcagat aagttagcat tgggcttacc atggtagcga aagcctcatt
    19801 tggtaaataa ccatctggga taaatagagc cgttaataca ccccaggcaa tcagtgctcc
    19861 aatatttggc atgaccatgc ttgataaagt actgcctaat ttttgtaccc tcgcttttag
    19921 cgaaatgttg tttttgggaa tcgtccgttc cattttgtct ctccctctct ccttttgata
    19981 ctctaattgt atccgcttac taaaaagaga aatagtcgta ctttggcacg aaactttgtg
    20041 ccaaaggttt gagtatgtca gcaaaataaa aagatttcgg tatcagaaaa cttcaatttt
    20101 aaataaaact gttattttaa tttttttata atatgcaaac aataactttt gttagcattt
    20161 aatttagatg ttttccattc tattatgtta ttaaatttta tattggaggc ctatctatga
    20221 cattactgat caaaaacatg aacatgaaac gtggtaaaaa acgtgtgatt cgacaattga
    20281 atcttttagt agaatcagga gaagtagctg ctttgattgc cccgaacgga tttggcaaaa
    20341 caactttgct gaatggcatt gcccaactgc tgccaacaac ttatgatcaa ttgtcccttc
    20401 acaacatctc tcctactgct tatacagatt atcgccggtc tttctttttt ctagaatcaa
    20461 cgaatcagtt atccgactat ctatcggctg ttgattattt gactttgatc aaatactatt
    20521 ggcagagcaa agtagaatgc caaactgttt tccaacgatt gaagatgact gagtacctta
    20581 ctttgccgat tggaaaaatg tctctaggaa tgaaacaaca tgtcttgctt gctgcttact
    20641 tgatcagtga ttcatctgtc atgttattcg atgaaccgtt gaacggatta gacccaggaa
    20701 gtattgatat cttgaatagc ctcatcagac aatggcagaa agaggggaag acgattcttc
    20761 tttcttccca cgctatcgcg aatatccaat cgatttgttc taaagcatgt tttctaaaaa
    20821 atggagaaat cgtcacagaa tcctcaaata tggaagagat tttagctatt tatcgtaaat
    20881 tatatgaggt gtaactatgt ctttacttac atttgaacgc aatctcttac taaaaaacaa
    20941 agtaaacttt ttatttcctc tattgttggt cgtgctcttt gcattcccac ttttttttga
    21001 tcataaactt gcttatacag aattcgatga actgaatcat aactatgaag agatgcaacg
    21061 tttgattgaa acgttgaaag aagatgagaa tgagaaagaa tttgtggaaa gtttagagaa
    21121 aagcaacaaa ctgatcgaag caatcttaca tgcaaaaaac acagggaatg tccagcaaat
    21181 ggtcgaagca acttatcatt atgaaaaaga tatactggat cgactgattt ctggtcaaag
    21241 acaaggaatt ccaatcattg aacaacaaaa acgtgtcgag ttgctccgtt atatgaaaga
    21301 acatcagatc caaagatatt ctatttttga cttgccagcg catctctctt tagcaaatta
    21361 ctacgaaaat attttttcag gaatgatttc tagttttttg attttatgta taaccgcctt
    21421 gtttctttct tccatcatct cttatgaaaa aagaaagcag gtaatctctc tagtcaatct
    21481 attactggat agtatggtaa agaaacatag catccgtttt accatttatt atggtgcagc
    21541 tatgctaagt ctcgtgatgc catttttgat cgtctctata ctagtaataa tcaaaaatgg
    21601 tttgggagac ttccgttatc ctgtaggaac gatcattggt caggagatac gaatcctgcc
    21661 gatgtatgag tatcttttcc agagctttct gttcctgttg ttgtgggtgc tctttttaag
    21721 tacaatcagt tttcttctat ctgctttatt tgaacattct ctagtcaatc ttttaggtac
    21781 acttctttgt cttttcttag cagagtatcg cttgttttct tcgattggat ggatagaatc
    21841 aatcagtcat tacttgccaa cttcttatgt tgattttcaa aatgtgatca taggaggaga
    21901 tattttctcg ccactagctt cagaacaggt tactttcatg aatggtatct tgacacttgg
    21961 tatatggagt atcgttttat tattcatagg tatgggcact atctatataa aaaagagcta
    22021 ttaaaacaca aaaataatag gggcggtgac aaaaaccttg tcaccgtccc ctatttcaaa
    22081 taaacggttt tctagaataa atagttttca aaagcttgca tccgcagtaa taagaacctc
    22141 ccaacaaaaa tagctcctct tatttttatc ttggttgaag ttattacttg atgcaaggca
    22201 gcttttttta ctgtgaacat tggttatata tgtccatgtt caaaaatcat ttggacttct
    22261 tcaatggttt ccgcatcact gagcgccatt acttggtcga tgtctgaaca gaaaaaggct
    22321 aaatcttgga gcaccgctaa ctgatgttct ttttttaaag ccactacaaa taagagtgtc
    22381 gcgatttttg gttcctcttt tgttccaaag tccacaccat caggcacttg gactaaatag
    22441 attccttctt ctactacttc ttcatctttg tcagtcccat gtggcaaggc tacgaaattc
    22501 ccgatataga cactcgcttt ttcttgtctt tcgatcattg attggatata tgccggtttg
    22561 attccccctt gttgggtcat ccactggccg atctcggtca acgcttcttt ccaattttga
    22621 taggattgat cgagcaatat tttttctgct ggtagctgta tcatcttttc accttcattt
    22681 ctttatttct tcaatcagga ttttcgctaa caactgataa acgatttctt tatttcctga
    22741 gcggaagatc tcggtgttca agtcattcat gatgattgct ccactgatct ttcctaaaag
    22801 aatcccgtct ttttcttgga ttggcgaagg cgccagcata actaacatac gggacaaatc
    22861 gactggctgt ctatccatcc cttcaatggt caacggatgt ttcaaattga aaatacaaaa
    22921 gatcggttta gaaatcaatg agctggatgt atggaataac cccatatttg tatgaggaat
    22981 accgataggt gcttgttcat atcgcttaag cagccggcga tgaaccacct cttcatccgt
    23041 tactagtcct tcaggaaaat aaggaaataa gctgcgaatc gtttcggaaa tcgtctcagg
    23101 attatccagt tcttggataa aaaaacgacc gagtaattga ttgatttgat ccatgaaatg
    23161 cattgtttcc tcataagtat cttctatcat ccactcgtta ttgctgttat acgtaatttt
    23221 ttgccttttt ttcttctcaa tatgcgaaaa agcttctttt agctgcttga cttcatcttc
    23281 tagcagtagc ggggagacta aaatatattt tccaccgtat cctggtaaaa tagatgtaga
    23341 aataacaaca tcatattctt cttgtaaatc gatttttttt aaatcagcaa tccgatagaa
    23401 atgaatttgt tggatgaagg gaaaatacct tttcaatcgt agttccaaca tgctagtaga
    23461 agctaatcca cttggcgaaa atcctgcaat actgatattg ctttctttcg gacttcgttc
    23521 caatgaattc gcaaaatgaa ggaccatata agcgatctct tcttcggata attttttttc
    23581 ttgaaaaatc cgctctactg ctttacggat tgcattcgca acttcctcgt attgaaccat
    23641 gattttttct aaaatcggat tggtcagtgt ctcttcttgt aaaacggctc ttgaaaacac
    23701 accagataaa tgagtcaaca gcattttgta caaagtttca tcttcataaa aatggacatt
    23761 cgtctcttca cttacttctt gaatcagttg ttttactaaa taagcaagct gtgtatcgaa
    23821 cgtctcttca aagaaattct gatcaaatga gttcgtgaag tcatttaata atcctgcaaa
    23881 aaagacgatc tcatttactg gataaagttg ttttgtctca gaagcgatcc gtgaaaacaa
    23941 tcgtttagct gtctgtagta attctttgtt tgccagacta ttatatgtct catttgtcag
    24001 taaatgattt ttcgtcacac gctccatcgt caatgtcagc atcaaaacca aatgttcaag
    24061 ctttctatca cttagattgg tctttttttg gatcaattct tccccgatta ctttgcgtgc
    24121 aagagataga tgttgcggat caacgaatcg aaaaaaataa ttcagtgatg catcgaaaga
    24181 aatactatga aaaagttcat attcattgat ttctaattct aatacattcg ctgtcagaag
    24241 ccggcggtat ttttccggtc cttcgatctc gtatccctgg ttccgaatga tttccaaagg
    24301 cagttggcga atactttctt ccaactgttt gatatctgca taaaaagtgg tattactgat
    24361 gcgatatgat tccatgaaat gagcaagact caacggctct gtcgtcagta acaactcggc
    24421 taaaatcgcg tgttgtcgtt tagcagtgga taagtcatta cttttcccat ctgtattttc
    24481 ttttaattgc tctaatactt cttctgatgc ctcaatgaca aatgagcctc tagctgcttt
    24541 tttcaaagaa gcatttaccg atttcaatga gacttcaaga ttatctaatt cgcggtaaat
    24601 agtccgttta ctgaccttca ataaattcat cattttttgg atagatacag gtgacgggct
    24661 actgagaaat tctgctaata attgtttttc tctgggcgat aaatacatct tatatttctc
    24721 ccttcacgag tttttcgtat tcattcgtag ctacccaatg ttcaactaga actagccgag
    24781 ggatcttttc ttctagctgt tcagttacag ctagttctct ttgtgcgata taaatcgttt
    24841 cttcttggat tttgattttt tctattgatt cttttgagat aacaaactgt tttttcgctt
    24901 tttttgctaa ttgacttaaa atcgtcatgc ccatagtttg tgagccgcgt ctgttgtttt
    24961 tatacaaaaa tacaatatta gcaggcgacg ttttttgttc tgtgatatct gctatctctt
    25021 ttttttcttc ccgctttgga aattggatcg cttcttttat tcgtgacagc aagatatctg
    25081 tttccaaaaa gtgatccagt acatagattt gactttgagg tactttttct cttgcaagac
    25141 ccgctagttc atgttgcacg ataaccagct gatttacttg gttattcaat tcatagatag
    25201 agctgtatcc gacagaaaga tcgatttttt ctgctgctaa tttctttttc agcagggcgg
    25261 ctcccatagc acttgatccc atacctgagt cgcaagcaaa aatgacggaa tgaatgatag
    25321 atggttccaa gatttctccc ctttctttga ccgttttgtt ctctttttct ttatttggta
    25381 atttcaatag tatcgctgca caaatgaagg tcacaaatgt actgattgct atccctatac
    25441 ttaccccagc tagttgtgga taaggcgcat tggcaaaaat cacgagtagt gacccaggcg
    25501 atacaggtgc agctaatccc gtatctaacc attgaaatat caacgtgccg cttgccccac
    25561 cagccattac agctaaaaat agatacggtc gcagcaagac aaatggaaaa tagatttcgt
    25621 gaatcccgcc aatcgcatgg atcatcaatg ctccactcgc atttactttt tcctgttttt
    25681 ctgcaaaaca aaggatagaa agtaagatcc ctaaaccagg tccaggattt gcctccatca
    25741 aaaataagga agagtacccg actgtttgtg agaattcgat tcctaaaggt gtcaatacac
    25801 catgattgat tgcattattg aaaaatagta cttttagagg ttctaagatc agactgacaa
    25861 gtggtaacag attcattgtg actagccaag acacaacgga ggcgagcaac aagtgaacac
    25921 tatttaaaac tggttcaata aaaacgattc caattataca aataacgcta ccagtcagtc
    25981 ctactagtag gttgctgaca agcatttcat atccagcctt gaatttcaca tggaatctag
    26041 aaacaaattg ttcatatacg atgccggcaa gcggcccgat aatcatcgct cctacgattt
    26101 gtggagcatt ggaacgagcg atcaacccta aagaagcaat tgcaccggcg actgcccctt
    26161 tttgtccccc taccgatttc ccgcctgaat aactgatcaa gatgggtaaa agcagctgga
    26221 tcatccaatg gcatacctct tctaatgtgg tgtgcaaatc gccagacaca ccttttgttg
    26281 ctaatgacaa gattccccaa gcgataaaca gacttagatt tggcatgatc atttcattta
    26341 agtgatgtcc agcttttctc agttgtttca tagacacgcg actgctgttg tttgctttcc
    26401 atttgtattc catctttttc accagacttc tatttattga tggacggatt ttatgtagaa
    26461 aaagcagcaa acgaaaaacc gtctgctgct ttcagctatc tgggaactat ttgcctggtt
    26521 cagacgcaat gattgctagt tcaccttgga ccgcccactc agaaacgcca tttggaataa
    26581 tacagcttgt tcctttttct aatggatatg tttttccgtc aacgacaagg tctcctgctc
    26641 cttcgattac cgtcatcaat gtataagggg cttgtttttt gaaagatgtg attcctttaa
    26701 tatcccactc atatacattg aaaaactcag tttctaaata agtgacgatc gatgaattcc
    26761 cttttcggac ttctttgatt tgtaattctg gtgttttcgc agggacagtt gttacatcga
    26821 tcgattgttg gatatgcagc tctcttgttt gtccttgcgc atcttttctg tcgtagtcat
    26881 acacgcggta agtcgtgtca gaactttgct gtgtttctaa aatcatgatt cctttaccaa
    26941 tagcatggat cgttccgctt ggtacataaa agaaatcacc ttttttaact ggtactttct
    27001 tcaaaaggtc atcccagcgc ccatctttga tcatctcagc tagttcttct cttgtctttg
    27061 catgatgacc atagatgatt tctgcaccag gttcagcatc gatgatatac cagcattcag
    27121 tttttcctaa ttcaccttca tgtttcatcc cataggcatc atctggatgt acttgtacag
    27181 atagatcatc ttctgcgtct aagatcttga tcaataatgg aaacactggt tctgaaggat
    27241 ggccaaacaa ttccttgtgt tctgaccata gttcatctaa tcttttccct ttgaattcgc
    27301 cattttctac tacactgaca ccatgaggat gcgcactgat cgcccaatct tctccgattt
    27361 tatcgttagg gatatcaaaa ccaaagactg aacgtaaacg acttcctccc caaatttttt
    27421 cttgaaaaac tggttttaaa aacataggtt cctgcataat tcaaactcct ctcatttttc
    27481 atagctatta tagcattatt tcggtaatac cgctttctct ttcaaaaagt tttcaacaat
    27541 ttcatctcga catatgagat actccgcacg atgatcgaca ggatgtacgc gatttgacaa
    27601 aaatatcaac gcttcttgtg tttttatatc aatcaagaaa aacgtacctg tataaccagt
    27661 atgaaaaaga atcgcatgac cgtcttctac atcctttttt aagtcccatc ctaaagaacg
    27721 atagccattt tttttcggtg tttgatcttg cagtaaagaa tcaatcgtct cttcttctaa
    27781 aaaacgacca ttacggattt ttcccttgtt caaatacatt tggacaaaag taatgctgtc
    27841 tttcaaatca ataaagagac ccgcgttacc tgcatgttca gccaaaactc ttgctttcgg
    27901 atcatgagtt tgtccacgca aaacctcacc cgaaggcagt tgttctgtgg gaacgatttt
    27961 tttggaagga aaaggaagaa ataagctgtt catcattcct aatggttcca atacttgttc
    28021 ttgaaagatt tccactgcag tttcttggta aatttcctct agcatcaacc caagaagaat
    28081 cgtaccggca tctgtatatt ttacttcttt tcctagttgc tcacctggtt ctagcttcaa
    28141 ataagcggcg atcaattctt cctgagatag cttatctctg tttggtatcc atgttttgat
    28201 atcagaagta tgtgtcagta aatgacgcaa agtgattgtc tgattttcaa attcaggaag
    28261 atatttatga agcggttgat cgagttctat ctttccatct tctaatagac gtaaaactaa
    28321 tgaagtggtt gcaacgactt tcgtcagtga ggctgcatca aacaacagat cttctgtcat
    28381 cagctgcttt tcaggaacga cttgggcaaa gccggctgta aatgtttcta cttgattttc
    28441 ttttatgaag gcgactgcta cacctggata aaatccttct tccatctttt tcaaaataag
    28501 ctgtttcgtg tgtggataca tctttttctc ctgcttttct atcagattct tacagtccaa
    28561 gcttaaagct taatctatga ggaatcaacc ttttttacac aaaaaaactg cgcgaaaaac
    28621 cgcgcagttt cccccggtat actattttct ctttctatct ctagaataag cgatagtatg
    28681 accgttcata aaatgacgag acatgcgaca atcgttaaga aagaaaaagt taagcgtcgc
    28741 atcgaatgtc agttttattc ttttcttttg gctcactgac gaaccaccat tcgattccta
    28801 tagcatcata gattgtgagt actgtgtgct ttttgtctaa gaagaaatca actgatagtt
    28861 gctgcaagtg agcaatcagt ccttccatgc tttcagtatc gatcatgaat ttcagaaaat
    28921 caagtccaat cacttcatct gtaggcaaat caattgcgcc tccgctagct tctgtcaaac
    28981 caacatggaa atctccttca ttcaatacat ggatgccctc ttcttcatta tgtaccttca
    29041 aaccaagtac atgattaaga aattggcgtt cttttgttaa gttagtaaca tttaaatgga
    29101 ttttttcaaa ataagaacct gttgatagtt tactgaattt ttcttcagat tttcttaata
    29161 atgcttcttg atccattgtt tctggaattt ctctttggtc gttcttattc tcttcatggt
    29221 aaatttccaa ttcattctct tctgggtcta cgagcaaaat ccccatacgt ccatgatctt
    29281 ctaaagcttc tttgattgga taattcattt tacggatacg acaaaggata tctgccattt
    29341 cttctgtgct agggataatc aatgaaaaac ggttcagctt tttgatcacc cccatgtgat
    29401 cattcgctct aggactttct tccagcagca acatttcact tccagcttct tctgttccta
    29461 aaatggctaa ttcgttttct tctcttttca aatcaaagcc aacaacgttc ttgtaaaaat
    29521 caatcatttt atctcggtct ttcacccgaa tggctacact ttttaaatag gtggcagccc
    29581 ccaattgaaa atctttcata tttcttgctc ccctctacgt caagctttat tttaacgatg
    29641 gattcttctt ctttcaagca ataactttga ttttgttaaa aaaaatgtga gaaaattcgc
    29701 attttgcttg ttttttgtaa attaatgagt aaaaactctt ataaaaagag gttgtgaaaa
    29761 agctgttctg catcaagtaa taagaacagc caaacaaaaa tagctcctcc tatttttcgt
    29821 ttggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg
    29881 aaaaagtcgc ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tctacatttt
    29941 tgcataaatt tggcttaata ccgagaaact ggcttttgaa caccgtttac caagaggttg
    30001 tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc ttctcaggtt
    30061 tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt aaggaagagg
    30121 ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa tagcttctca
    30181 tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg tttattcgga
    30241 aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa atttgtacta
    30301 ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata gaatccgtct
    30361 ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt catcacaata
    30421 atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact tgtccggttt
    30481 tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc tacactagat
    30541 gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc aattgtgatt
    30601 agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt gttatatcct
    30661 tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc aatgatttgt
    30721 tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc tgtaaacagc
    30781 caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga aagatcacgg
    30841 gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg ttcaagaagg
    30901 ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat ctcaccaggt
    30961 ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc gaattgaaca
    31021 ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga tttttcattg
    31081 gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac tgttgattgg
    31141 atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt tgtatattgc
    31201 aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac tccgcctagt
    31261 acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat gatgattgcc
    31321 gaaataaatt gagctttcca accagcggca tacagattct gattttcttt ttcaaatact
    31381 tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc atatgtttct
    31441 tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa cacttgtgat
    31501 ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa cgcgactaac
    31561 gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt gactgcacta
    31621 gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat atcattgatt
    31681 gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg tacacgattc
    31741 attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac acgtgtcata
    31801 ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat tactgtcgca
    31861 atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg gccttgttgc
    31921 atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt ccccaagacc
    31981 tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac agcgatgatc
    32041 gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca gaaattttta
    32101 ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg accgcctgct
    32161 ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct cttagttgtg
    32221 aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt gttcctttgc
    32281 caaccagttt tccttcatct agcacaagga tcatatctgc atccattact gtacttactc
    32341 gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct tggcgaagat
    32401 tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag atatctgctg
    32461 ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag aagtttcctc
    32521 ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa tctttagctt
    32581 gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta ccatactgca
    32641 tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag cccattaatt
    32701 ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg atcgaaccag
    32761 attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct gaaccagtcc
    32821 cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct tccaatgcaa
    32881 gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt gcgttttttc
    32941 cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt tcatccaaca
    33001 cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa atagcggaaa
    33061 gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc agattaccga
    33121 cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct acgtttgtac
    33181 cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta actttgattg
    33241 ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag cgtgtcttat
    33301 cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg tttaaacggt
    33361 cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt ccgccgatca
    33421 aaataatcat tactgggatg acaactaaga agatttttgt caactgatga tctttttgat
    33481 aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata cgtaaaaaca
    33541 tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc aaagaggccg
    33601 ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag acatccgtac
    33661 gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt gcgatagcag
    33721 ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa atataatcga
    33781 catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc aaatataaat
    33841 ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc aaggagatcc
    33901 gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg tttttcagcc
    33961 aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct tcagatgttg
    34021 aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact aattggatca
    34081 gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc aattcaagca
    34141 actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt tggcgactcg
    34201 tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag ttacgataaa
    34261 aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag gattcgaatc
    34321 ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta gagctgtcac
    34381 gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa tactgataga
    34441 aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct tcttttaagg
    34501 gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt tctttaggca
    34561 aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg acacattgtc
    34621 atatgacgct atgtcattat aacacctcct acctgttttg caagacattt gcatagtttt
    34681 tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat ttgaattaat
    34741 gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat ggcccaatca
    34801 attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt tttagataca
    34861 agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat ccccgctgct
    34921 atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat tctaagctat
    34981 acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt tcgtgctgtt
    35041 tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt gcttgttaga
    35101 ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct gtcttttttt
    35161 agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt tcgagtaaac
    35221 tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt aagcatatgg
    35281 catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc acagttaagg
    35341 cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa gtgactgttt
    35401 tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca ggttgggaag
    35461 cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa aaaattgctc
    35521 gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc gcaaacgcct
    35581 tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc aatgtagctg
    35641 gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt aaaaaagcac
    35701 tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct caatatgtaa
    35761 aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc gaaggaatcg
    35821 attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa gctgctgctt
    35881 taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag gaaaaaatct
    35941 tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt attctttctg
    36001 ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt caaaaacatg
    36061 agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac cgatgattcc
    36121 gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga ttgctaactg
    36181 attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta ctgcaaaaac
    36241 gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga tagccggaat
    36301 catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa taatccccaa
    36361 cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga ttgccacagc
    36421 aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca tttcactcag
    36481 cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat aaggtgctaa
    36541 ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca gagccactaa
    36601 aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct tagatatatc
    36661 ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca actgttcgcg
    36721 aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa tcgtatctac
    36781 atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag ggatgatcac
    36841 tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga tactgtaaag
    36901 ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt aatacaagat
    36961 tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg gtgcaaacaa
    37021 atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa caagtaaggc
    37081 tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc tgttcttctt
    37141 attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc caaaccaata
    37201 gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc ttctggacaa
    37261 gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc catcggaccg
    37321 acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc tttcaaagaa
    37381 aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc agctgttgct
    37441 gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt cccaatttct
    37501 gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa cagtataaca
    37561 cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg aaaactattt
    37621 cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg aacctatacg
    37681 cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga agaattagcc
    37741 aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag taaagctggc
    37801 aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta cgataaggat
    37861 tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt agcggttgat
    37921 gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa tgtctaccat
    37981 atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga agcgacaggt
    38041 cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc tgaccaacga
    38101 ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc cgaaaacggc
    38161 aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg ccatcttgtc
    38221 tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac agtccgcgtg
    38281 ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc gaccttgcca
    38341 gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga tggcaagttc
    38401 ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt tgaagatggt
    38461 tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg cgatttcgca
    38521 ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa tctgacatta
    38581 tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt ctatgtacca
    38641 gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat gaatcagcaa
    38701 gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg gaaaatcgaa
    38761 gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca gaactacttt
    38821 gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg aaaagaacat
    38881 caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa accgccgaga
    38941 tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca aggttgttgt
    39001 tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa aggtaatatt
    39061 acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt attttttcaa
    39121 caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt ggtcttgttt
    39181 tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga tactttggat
    39241 catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt tatgaatgcc
    39301 cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc gatatttttt
    39361 tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca gttcacttgt
    39421 ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc cttctccgat
    39481 tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa tattcggtaa
    39541 catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg tttttatcct
    39601 caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat tcttattcgt
    39661 gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca tattggatca
    39721 attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct ttataccact
    39781 gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct aatgataaaa
    39841 gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc gctgcaaaat
    39901 aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct ttactgtcga
    39961 acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg atcgtatctg
    40021 aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta gaaagattct
    40081 tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct tgcagataat
    40141 tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct agattatcat
    40201 actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac tgaggtgttt
    40261 tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa atatatggat
    40321 tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg tcaaatccta
    40381 atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg atcgctgtcg
    40441 tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc atttttggta
    40501 caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa aaaccagtca
    40561 atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc atattgccac
    40621 tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat acttctacgc
    40681 cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg ttcggcgact
    40741 cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca gtgatttctt
    40801 tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc agattgtaca
    40861 aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa ggtatccata
    40921 gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa ttactgatat
    40981 accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg aatcgccttc
    41041 cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt cctgcggcag
    41101 ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg atttcagtga
    41161 tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc atataatttg
    41221 caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg acagatcctg
    41281 ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag aagaattttt
    41341 ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca ttttgacacc
    41401 actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt gctgctgttc
    41461 cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc aaatgcttgc
    41521 tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta cgaaattcga
    41581 aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt tatggccttt
    41641 ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc tgttgtttca
    41701 cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag acatgctcat
    41761 tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc agagaaaata
    41821 tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac ggcgcttgga
    41881 aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac aaaagataat
    41941 cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga gtcgatcccc
    42001 ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct ggaaaatcag
    42061 tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat ttatcaacaa
    42121 tttcacttct tcctacattg ataagtacag catctttttt cattttttct atattcgcct
    42181 gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg taatccgagg
    42241 tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca tcgcggatag
    42301 aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt gtgcctatcg
    42361 ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca taagcacttc
    42421 ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc atacgacttg
    42481 cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct tttactgcat
    42541 tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct ttttcaacgt
    42601 tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt gtaagccatt
    42661 catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca tctattattt
    42721 tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca atcaaatgaa
    42781 cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc aattagacaa
    42841 ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt aggctgagtg
    42901 ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag caaaatattg
    42961 agggtgagat atcttgataa atggtgttcc gttagctgac attgataata agactaaatt
    43021 tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa ctaagtggct
    43081 ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat tttgcccacg
    43141 tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg ccacctgcct
    43201 gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac acacgtgcaa
    43261 caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg atcagcagtt
    43321 tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct ttcccatcaa
    43381 atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca acgattcttg
    43441 gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag attgcttctt
    43501 ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc cctcgagcca
    43561 tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca gcaaaaccgt
    43621 atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt ccatacaggt
    43681 cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg cgaataccga
    43741 tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca taatcaccat
    43801 agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct tcgtctgata
    43861 cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc caaccaaatt
    43921 gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg ttgtcaccaa
    43981 aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc atccaatcag
    44041 caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta ttttgtttat
    44101 ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga tttaaattca
    44161 tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta gctaaatgaa
    44221 gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt gagaaagtat
    44281 gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc atgatttttg
    44341 tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc aattggccat
    44401 tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc agtgcttctt
    44461 ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca atattcaaca
    44521 taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg tgttttcgta
    44581 aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg agctgtctgg
    44641 taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc gcactttgcg
    44701 catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga attgctaagg
    44761 gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca tattcgtacc
    44821 cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca taaaaagtat
    44881 ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag atcgtcgccc
    44941 atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat aaaacagcat
    45001 gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg tccaagtcca
    45061 caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt ttgataacga
    45121 aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg acgagtccgt
    45181 gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc agcattttct
    45241 atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat cccctcacgg
    45301 taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt gatggtgatt
    45361 ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt cccatgtcga
    45421 tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc ggctgtgtcc
    45481 atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac ttctggtgtt
    45541 ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga tttcaatata
    45601 tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat gaaattcgct
    45661 aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt tactcctgta
    45721 atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt atcgccttct
    45781 agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat acccaaagaa
    45841 ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca gttattcgta
    45901 tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc cggatggaca
    45961 ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc cgaaatgttc
    46021 cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc cccttctggc
    46081 ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata agcccctgat
    46141 tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat gtgatccaag
    46201 tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat ttcttgatgg
    46261 taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac gcctagtact
    46321 ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa attaatttct
    46381 ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact ccatctctgc
    46441 ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt gattgtattt
    46501 cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag ataaccgtgc
    46561 atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata gatttcgaat
    46621 acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc ttctaatgaa
    46681 taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc ggcaatagga
    46741 gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc aatccctaaa
    46801 gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt cataatgatt
    46861 taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc ttacaatgat
    46921 tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca ataaaaaaca
    46981 cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg atcaaccgcc
    47041 ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt ttcctcatcg
    47101 tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat tggtgttatg
    47161 accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc ttctttgata
    47221 ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt atctggtctt
    47281 ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat ttttatggct
    47341 ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat tgcagcaagg
    47401 attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta tatgtctgaa
    47461 atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat gattgcttct
    47521 ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga aacgatggct
    47581 tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt cggtgtttta
    47641 gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga ggcaaaaaga
    47701 gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca aatccagctg
    47761 aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt agaaaaatat
    47821 cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca aggagctaat
    47881 gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc agcgagcgat
    47941 gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt gctctttttg
    48001 gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag cgtgatggga
    48061 ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac aaattcgttg
    48121 ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg ggctccactg
    48181 acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc atctggccta
    48241 gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc tgtgatgact
    48301 gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt tttaggggtt
    48361 ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga aatcgaacaa
    48421 agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta aagaggttgt
    48481 gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag tcacaaggaa
    48541 caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac cagttggtag
    48601 gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc gatgacaaaa
    48661 gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta aaaacccgtc
    48721 tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc atagagaata
    48781 tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc atcttgtccc
    48841 aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg gcttaaagaa
    48901 gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt ttctgtcaac
    48961 ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc taaagcttgt
    49021 tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc cgtggtgaaa
    49081 gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct gataaaacct
    49141 ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag acgctgatgt
    49201 ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc taaacaaata
    49261 taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat gccttgttct
    49321 ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt aggctcaacg
    49381 atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc caattcgtga
    49441 tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc attttcgatt
    49501 cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac accgatcgtt
    49561 tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata tgtgcccgac
    49621 cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg ccgaatcgta
    49681 tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt tgtatttact
    49741 tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg atattttgcc
    49801 atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg caaggtttat
    49861 tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt caccaaattc
    49921 tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat taggattgtc
    49981 taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa tatcaaagca
    50041 cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat tttttttaga
    50101 agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa gattcttgtg
    50161 ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac cagaatacgt
    50221 aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg aaaaaccccg
    50281 tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta acgtccaagg
    50341 attatccatt tcggatagat aaagattaga attcccagta atttcaggat cttgttgggc
    50401 ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac tgaaagtttc
    50461 ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat ctatatgctg
    50521 attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt tatgattgct
    50581 tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg cccagatcaa
    50641 ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag catgttctaa
    50701 ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa ccgatcctgt
    50761 aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt gccgaacgat
    50821 aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt tattctaatt
    50881 acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc tattgaaaaa
    50941 tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc caacagatcg
    51001 ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg ttcaatcgtt
    51061 atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt gccgttatct
    51121 acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata aacagggcaa
    51181 atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg catcacataa
    51241 taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg tattgtgttt
    51301 actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat agccagccct
    51361 aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat gggactaccg
    51421 acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc atcaaacgct
    51481 agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt agcaacgatt
    51541 tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt atcatcacgc
    51601 tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata gttatgcaaa
    51661 gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca ttcagggtac
    51721 gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc atccactaac
    51781 ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact cttagccccc
    51841 acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc aaaaggcttt
    51901 ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa attacaatat
    51961 tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt gaatatcggt
    52021 ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga atttggttct
    52081 atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc tacagtatcc
    52141 acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc taattctaat
    52201 tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt ttcatggccc
    52261 ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga gccaaacagc
    52321 cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac ttcttcgtcc
    52381 aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag tttccatacg
    52441 ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac aaatcctaat
    52501 aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca tgcactttgt
    52561 tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat ccaggataaa
    52621 agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac gattgtctgt
    52681 tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact aaggaacaag
    52741 ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt tcctgatccc
    52801 tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac gatagtaata
    52861 acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga aaccacaatc
    52921 aactgtccat aaagtttagt ctcaactatt ttcatcttcc tcactctttc attccagaca
    52981 tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt aatggcagca
    53041 ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc cctgtaaata
    53101 aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc aatggataaa
    53161 gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga gtaggtttgc
    53221 tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca atgcgtgctg
    53281 cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag ataccaaatg
    53341 cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca agcaaattga
    53401 cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc agcaaaacga
    53461 aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac cccgcaagag
    53521 aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta tttttgatgt
    53581 aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta tagctatctg
    53641 caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa gaaataatca
    53701 gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc gttcgaatga
    53761 tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag ctttctggtg
    53821 ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta cacattagtg
    53881 gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga tgcatagccc
    53941 aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt ttctgtctta
    54001 aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat cgaaccaatc
    54061 agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt aatgttaaaa
    54121 aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga gggagagatt
    54181 ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca aacagtcatg
    54241 atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat cggcaagccg
    54301 acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat agaaaaaata
    54361 atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg acaaaaacga
    54421 ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat aatttgtgtt
    54481 ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc tcgttcatca
    54541 ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa gaaaatattc
    54601 aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa taataataaa
    54661 actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt ccaatatttg
    54721 gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac aatcttggtt
    54781 taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata acacctatct
    54841 gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat cctgtataaa
    54901 gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt catgagtgtc
    54961 tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc gttattgatc
    55021 gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg tttcgataat
    55081 tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc caagtaggca
    55141 ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca atatttcaaa
    55201 aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc atatcctacg
    55261 ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt agtcacatta
    55321 taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat ttcaatggct
    55381 agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc tggaccagtc
    55441 ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc aggagacgca
    55501 aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa catccagtta
    55561 tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt actactatca
    55621 gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg ttcagtatct
    55681 aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg tacctgcatg
    55741 gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc tttaaaatca
    55801 gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc tccgttttct
    55861 acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt tttagaagaa
    55921 atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat ttcaattttg
    55981 atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat ttcaccatca
    56041 gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc agattctgct
    56101 gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa agagccaatt
    56161 aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac atctgaccac
    56221 attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt ttacatttgt
    56281 tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg tatcaaatcc
    56341 actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt gaacagttag
    56401 attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt catttattac
    56461 ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt ttgctgaacg
    56521 aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa atggataata
    56581 gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa taacatttac
    56641 caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag tgattaatag
    56701 acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag gaggagcaat
    56761 ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat tccattcatc
    56821 aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat cgcacatcgc
    56881 tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat gagaaagatc
    56941 atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat cgtacgcttg
    57001 atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg aacttccgca
    57061 taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt cctctgctaa
    57121 ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca tttcattccc
    57181 taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc ttaaatcact
    57241 ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg catctactcc
    57301 acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac accagttata
    57361 aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat ccaaccttct
    57421 aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca caaaatttcc
    57481 accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga cgtcttggcg
    57541 aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat atactgctcg
    57601 tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta cacgcttgac
    57661 actactaatc aacattgtgg cttccataac tgacctcctt taatttatac atgaataata
    57721 cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt tttatcgatt
    57781 ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac ttttattaac
    57841 aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa ctacaaataa
    57901 acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc aagatcatcc
    57961 agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt ggagtgagca
    58021 gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc aaaacagaaa
    58081 aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc agttttccag
    58141 aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt cactatacaa
    58201 attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc gggaaagtgg
    58261 atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc tggtttacca
    58321 gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca ttggagatgt
    58381 tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat tggccttcag
    58441 atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct ggagattttg
    58501 ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat caatacggct
    58561 tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa cccttgtcaa
    58621 acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga atcgaagtga
    58681 aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc ggtaattacg
    58741 atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta ttttataaaa
    58801 caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta tttccagaaa
    58861 tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca ccatgcttcg
    58921 attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc aatttcatta
    58981 tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc aagatctgca
    59041 gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa ttgtttccct
    59101 tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc aaatttcgtg
    59161 aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc tgctctttct
    59221 ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc tttgttaaaa
    59281 tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac agctggtttg
    59341 atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt tgcatcttct
    59401 tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt ttcatctttt
    59461 gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa agtagaatct
    59521 tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt caaatatgct
    59581 ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg tttgacacct
    59641 aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct tctgtatgaa
    59701 gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc cagcattcag
    59761 tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct tcccatagtg
    59821 aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat tcgtaaactc
    59881 tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct cgaacagttt
    59941 tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct cgagggtctt
    60001 catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga gtgatgcgcc
    60061 acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac ttgatcgtat
    60121 ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca ccaagggctg
    60181 gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt ttagcttttt
    60241 gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag atttttgctt
    60301 ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag gccatatctc
    60361 cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc gccacgcgaa
    60421 tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac acgcagtctt
    60481 tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat tggactaacg
    60541 aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt acattgcttg
    60601 ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca tccagttctt
    60661 gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat ttgatacgag
    60721 ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct gtttctacta
    60781 attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca aaaactagtt
    60841 ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa tactccaaaa
    60901 aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca ttgaacgtca
    60961 gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat ccgtggttaa
    61021 aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga cctaattccc
    61081 agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa ctgtcgtctg
    61141 ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc tacccattat
    61201 aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc acatgtttta
    61261 cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct tattggtatt
    61321 taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg aagaaattag
    61381 cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa tcgtagccgt
    61441 taagataccg atgattgaac aaatataacc aaatgtctct acaacataat caatggcaaa
    61501 agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa gaaacggata
    61561 taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata taccttgcgt
    61621 tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt aagaaagcag
    61681 ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct tgttttttat
    61741 tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt tattaaatag
    61801 aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt ttgaattgta
    61861 ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct tctcgtgtca
    61921 tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt ttcttcgtat
    61981 tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt gttcgatcta
    62041 acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc actactttag
    62101 gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc ttcatctcat
    62161 tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca tctttcctag
    62221 cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct tttatcactt
    62281 aatagtataa cataatttcg tgagaaaaaa atacaatttt ttcttgacca tctcgttacg
    62341 taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa taaagaaaat
    62401 gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga ttggactgct
    62461 aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag aagtcgatcg
    62521 tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata tccaagaggt
    62581 cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc aaatgttgct
    62641 ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac ttgatatgta
    62701 cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac aacaaaagtt
    62761 gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa aaaaaaaggt
    62821 tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag aaatgcaaac
    62881 tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag aagatgaaag
    62941 cttagcagac cgtatcttcc aagctcataa gaagtggttc tcttacagct ggcctgaata
    63001 tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac ggttcactgc
    63061 atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa ttatccaaaa
    63121 aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac ctaataacaa
    63181 aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc cattctttca
    63241 caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata aggtattttc
    63301 actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca agcttccaga
    63361 tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc gcgtccaatc
    63421 accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac catatccgaa
    63481 tttgtaaaga caccatcaac tccaagctct ttaaaaaaga agcctgcttg ttttcctttc
    63541 tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa aagttgatga
    63601 catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc caacgtgatg
    63661 cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat tgattgttct
    63721 cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa aactagaggt
    63781 ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt aatgatcaat
    63841 ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc tttatgatag
    63901 cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat gatcccactg
    63961 atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat gcttttcgtt
    64021 tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc tttcatgacc
    64081 gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat tacacgtgaa
    64141 atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc cactgctgct
    64201 tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga ccgcattcaa
    64261 aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc caatatatat
    64321 cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc ctattcaacc
    64381 cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca taaaaataat
    64441 tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct ccttttgata
    64501 ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc caaagaaaag
    64561 ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac attataatga
    64621 tactgtaaat atatctttat tattagtgaa tg
//
LOCUS       DADVXK010000007        60016 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.007, whole genome shotgun sequence.
ACCESSION   DADVXK010000007 DADVXK010000000
VERSION     DADVXK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.007"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(51..899)
                     /locus_tag="KB909_000406"
     CDS             complement(51..899)
                     /locus_tag="KB909_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6836467.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1123..3063)
                     /gene="thrS"
                     /locus_tag="KB909_000407"
     CDS             complement(1123..3063)
                     /gene="thrS"
                     /locus_tag="KB909_000407"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBB6836468.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3400..3579)
                     /locus_tag="KB909_000408"
     CDS             complement(3400..3579)
                     /locus_tag="KB909_000408"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBB6836469.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3626..5449)
                     /gene="cadA"
                     /locus_tag="KB909_000409"
     CDS             complement(3626..5449)
                     /gene="cadA"
                     /locus_tag="KB909_000409"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6836470.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5727..8006
                     /locus_tag="KB909_000410"
     CDS             5727..8006
                     /locus_tag="KB909_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6836471.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8099..8746)
                     /locus_tag="KB909_000411"
     CDS             complement(8099..8746)
                     /locus_tag="KB909_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836472.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8925..9644)
                     /locus_tag="KB909_000412"
     CDS             complement(8925..9644)
                     /locus_tag="KB909_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6836473.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9775..10926)
                     /locus_tag="KB909_000413"
     CDS             complement(9775..10926)
                     /locus_tag="KB909_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBB6836474.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11143..11883)
                     /locus_tag="KB909_000414"
     CDS             complement(11143..11883)
                     /locus_tag="KB909_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6836475.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11887..12210)
                     /gene="rsfS"
                     /locus_tag="KB909_000415"
     CDS             complement(11887..12210)
                     /gene="rsfS"
                     /locus_tag="KB909_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBB6836476.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12267..12860)
                     /gene="yqeK"
                     /locus_tag="KB909_000416"
     CDS             complement(12267..12860)
                     /gene="yqeK"
                     /locus_tag="KB909_000416"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBB6836477.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12844..13494)
                     /locus_tag="KB909_000417"
     CDS             complement(12844..13494)
                     /locus_tag="KB909_000417"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBB6836478.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13504..13815)
                     /gene="yhbY"
                     /locus_tag="KB909_000418"
     CDS             complement(13504..13815)
                     /gene="yhbY"
                     /locus_tag="KB909_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBB6836479.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13831..14940)
                     /gene="yqeH"
                     /locus_tag="KB909_000419"
     CDS             complement(13831..14940)
                     /gene="yqeH"
                     /locus_tag="KB909_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBB6836480.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14937..15464)
                     /locus_tag="KB909_000420"
     CDS             complement(14937..15464)
                     /locus_tag="KB909_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBB6836481.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15644..16429)
                     /locus_tag="KB909_000421"
     CDS             complement(15644..16429)
                     /locus_tag="KB909_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBB6836482.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16422..17291)
                     /locus_tag="KB909_000422"
     CDS             complement(16422..17291)
                     /locus_tag="KB909_000422"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBB6836483.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17292..18671)
                     /locus_tag="KB909_000423"
     CDS             complement(17292..18671)
                     /locus_tag="KB909_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBB6836484.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18679..19098)
                     /gene="fabZ"
                     /locus_tag="KB909_000424"
     CDS             complement(18679..19098)
                     /gene="fabZ"
                     /locus_tag="KB909_000424"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6836485.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19123..19599)
                     /gene="accB"
                     /locus_tag="KB909_000425"
     CDS             complement(19123..19599)
                     /gene="accB"
                     /locus_tag="KB909_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBB6836486.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19602..20837)
                     /gene="fabF"
                     /locus_tag="KB909_000426"
     CDS             complement(19602..20837)
                     /gene="fabF"
                     /locus_tag="KB909_000426"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBB6836487.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20856..21593)
                     /gene="fabG"
                     /locus_tag="KB909_000427"
     CDS             complement(20856..21593)
                     /gene="fabG"
                     /locus_tag="KB909_000427"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBB6836488.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21605..22522)
                     /gene="fabD"
                     /locus_tag="KB909_000428"
     CDS             complement(21605..22522)
                     /gene="fabD"
                     /locus_tag="KB909_000428"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6836489.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22629..22853)
                     /locus_tag="KB909_000429"
     CDS             complement(22629..22853)
                     /locus_tag="KB909_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6836490.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22906..23868)
                     /locus_tag="KB909_000430"
     CDS             complement(22906..23868)
                     /locus_tag="KB909_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBB6836491.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23878..24318)
                     /locus_tag="KB909_000431"
     CDS             complement(23878..24318)
                     /locus_tag="KB909_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6836492.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24624..25589
                     /locus_tag="KB909_000432"
     CDS             24624..25589
                     /locus_tag="KB909_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6836493.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25646..25876)
                     /locus_tag="KB909_000433"
     CDS             complement(25646..25876)
                     /locus_tag="KB909_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBB6836494.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25962..26849)
                     /locus_tag="KB909_000434"
     CDS             complement(25962..26849)
                     /locus_tag="KB909_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBB6836495.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26938..28161)
                     /locus_tag="KB909_000435"
     CDS             complement(26938..28161)
                     /locus_tag="KB909_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6836496.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28178..29224)
                     /locus_tag="KB909_000436"
     CDS             complement(28178..29224)
                     /locus_tag="KB909_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6836497.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29388..31115)
                     /gene="ptsP"
                     /locus_tag="KB909_000437"
     CDS             complement(29388..31115)
                     /gene="ptsP"
                     /locus_tag="KB909_000437"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBB6836498.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31115..31381)
                     /locus_tag="KB909_000438"
     CDS             complement(31115..31381)
                     /locus_tag="KB909_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBB6836499.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31860..34094
                     /locus_tag="KB909_000439"
     CDS             31860..34094
                     /locus_tag="KB909_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6836500.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34242..34562
                     /locus_tag="KB909_000440"
     CDS             34242..34562
                     /locus_tag="KB909_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6836501.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34767..34991)
                     /locus_tag="KB909_000441"
     CDS             complement(34767..34991)
                     /locus_tag="KB909_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBB6836502.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35189..36769)
                     /locus_tag="KB909_000442"
     CDS             complement(35189..36769)
                     /locus_tag="KB909_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBB6836503.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37170..38546)
                     /locus_tag="KB909_000443"
     CDS             complement(37170..38546)
                     /locus_tag="KB909_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6836504.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38674..39792)
                     /locus_tag="KB909_000444"
     CDS             complement(38674..39792)
                     /locus_tag="KB909_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6836505.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            39934..40368
                     /locus_tag="KB909_000445"
     CDS             39934..40368
                     /locus_tag="KB909_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836506.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40446..40979)
                     /locus_tag="KB909_000446"
     CDS             complement(40446..40979)
                     /locus_tag="KB909_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBB6836507.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41073..42251)
                     /gene="mutY"
                     /locus_tag="KB909_000447"
     CDS             complement(41073..42251)
                     /gene="mutY"
                     /locus_tag="KB909_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBB6836508.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42244..43041)
                     /gene="recX"
                     /locus_tag="KB909_000448"
     CDS             complement(42244..43041)
                     /gene="recX"
                     /locus_tag="KB909_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBB6836509.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43148..44530
                     /gene="rlmD"
                     /locus_tag="KB909_000449"
     CDS             43148..44530
                     /gene="rlmD"
                     /locus_tag="KB909_000449"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6836510.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44704..45282)
                     /locus_tag="KB909_000450"
     CDS             complement(44704..45282)
                     /locus_tag="KB909_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBB6836511.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45604..46074
                     /locus_tag="KB909_000451"
     CDS             45604..46074
                     /locus_tag="KB909_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBB6836512.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46182..47408)
                     /locus_tag="KB909_000452"
     CDS             complement(46182..47408)
                     /locus_tag="KB909_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6836513.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48162..48362)
                     /locus_tag="KB909_000453"
     CDS             complement(48162..48362)
                     /locus_tag="KB909_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6836514.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48496..49104)
                     /locus_tag="KB909_000454"
     CDS             complement(48496..49104)
                     /locus_tag="KB909_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBB6836515.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49189..49659)
                     /locus_tag="KB909_000455"
     CDS             complement(49189..49659)
                     /locus_tag="KB909_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBB6836516.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49707..50621)
                     /locus_tag="KB909_000456"
     CDS             complement(49707..50621)
                     /locus_tag="KB909_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6836517.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50767..51570
                     /locus_tag="KB909_000457"
     CDS             50767..51570
                     /locus_tag="KB909_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBB6836518.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51748..52695
                     /locus_tag="KB909_000458"
     CDS             51748..52695
                     /locus_tag="KB909_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBB6836519.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52763..53056)
                     /locus_tag="KB909_000459"
     CDS             complement(52763..53056)
                     /locus_tag="KB909_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBB6836520.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(53084..53749)
                     /locus_tag="KB909_000460"
     CDS             complement(53084..53749)
                     /locus_tag="KB909_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBB6836521.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(53889..54521)
                     /locus_tag="KB909_000461"
     CDS             complement(53889..54521)
                     /locus_tag="KB909_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6836522.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54528..55595)
                     /locus_tag="KB909_000462"
     CDS             complement(54528..55595)
                     /locus_tag="KB909_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6836523.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55592..56323)
                     /locus_tag="KB909_000463"
     CDS             complement(55592..56323)
                     /locus_tag="KB909_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBB6836524.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56492..56971)
                     /gene="greA"
                     /locus_tag="KB909_000464"
     CDS             complement(56492..56971)
                     /gene="greA"
                     /locus_tag="KB909_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBB6836525.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57107..58282)
                     /gene="mltG"
                     /locus_tag="KB909_000465"
     CDS             complement(57107..58282)
                     /gene="mltG"
                     /locus_tag="KB909_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBB6836526.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            58486..59655
                     /locus_tag="KB909_000466"
     CDS             58486..59655
                     /locus_tag="KB909_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6836527.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT        17426 a        12594 c        10125 g        19871 t
ORIGIN      
        1 aaactacgtt ttgttattct aaaaaactta tataaaaaat agtaaggttt ttatttcgaa
       61 tccataaaat attcttggat tgcttctcgt gtttttttca ctttttcgct aagcttttcg
      121 tttttagcca tatagaaata aaaaatgata tcgatcgtag caaattgggc caaaagtgaa
      181 ttagttgccg cacttcgatt cgtgatttct tttggtctag atgtttgtac gagtacatcg
      241 gctatcttgc taagcgggtt atttccaaat tgcgtcaacg caatgatttc gatattcatg
      301 cttttcgcca gctcggctaa tgcgactaca tctgcacttc tacctgagtt tgaaacaagc
      361 caaagcactt tctttttctc attgctgaca agttgcggga gcaagacgtg gatatctttt
      421 tcaaaaatga ttggcttacc gacacgagac catttttgca gaatatcttc tactactaaa
      481 gaagaggcgc caaccccata taaaaaaaca gtctctgccg attccaaaca ctctacgact
      541 ttttggatcg tttcttcttc tagaatatct actgtttctt ttatcgctac ttgtgcattg
      601 ttaccaagtt tgtttttgat agagtaaaag gactcatttg cttctatatc actaaaacct
      661 tcatcgattc cagtctgtag ttctgttgaa atcgtgattt tgaagtccgt cagactttga
      721 aaaccgattt ttttggaaaa acgtacaact gtcggcgcac tcaacccgga agcttctgct
      781 aattcattag ctgtcattgt agggaccttc tcaatattac cgataatgta gttggccaac
      841 tttttttctg ctgaagaata atcttccatc atactttcaa tacgactaat tacgctcata
      901 agttcctcca cccttttaat gatagtctat gtaagtatac catatcagac ccttattcac
      961 ggtcgtatac tggataaaaa acaaaaaaac aatccgccca acagaatatc ttatcccatc
     1021 aatcccacag attctattga gcatctgtgt ctttgaggaa tacctgttat ctattgttcg
     1081 gattgctttc tatctactac ttttttacag gaaatttacc tattagtttt ctctgctgta
     1141 atttttgact tctgcttcca tagcatcaat aaagatattc aaatcttcta cagctgtttc
     1201 tttacttcca taacgacgta cgttcactgt tgcatcttcc aattccttgt ctccaacaac
     1261 taattggtaa gggatctttt gtgtttgaga ggcacgtatc ttatagccca ttttttcatt
     1321 acgatcatca acttctacac gcaacccctt catttgcaaa cgttctttga tttcataagc
     1381 ataatcgcca tgtgcatcaa cagaaacagg gatgattgtt gcttgtatag gtgccaacca
     1441 tgttggaaaa gcgcctttgt atacttctgt taaataagcg acaaaacgtt ccattgtaga
     1501 aacaattccg cggtggataa ctactggacg atgcgtattt tccccgtctt ctccaacata
     1561 tgtcaaatca aagcgctctg gcaataagaa gtctaattgt atagttgata atgtttcttc
     1621 tgtaccaaga gctgttttga cttgaacatc tagttttggt ccgtaaaagg ctgcctcgcc
     1681 ttctgcttca aagtaatcta gttctaattc atccatagcg gctttcagca ttgcttgggc
     1741 tttttcccac attgcgtcat catcaaaata tttatctgta ttgtttggat cgcgatagct
     1801 caagcggaaa cgataatctg taatattgaa gtcagcatat actgccacca tcaattcaag
     1861 cgtacgttta aattcatctt tgatttgatc aggacgaaca aatgtatgac catcattcaa
     1921 cgtcatttct cgtacacgtt gtaaacctga caaagcacct gatttttcat agcgatgcat
     1981 cattcctaat tcagcgatac gaattggtaa ttcacgataa gaatggatcg tgtttttgta
     2041 gaccatcatg tgatgagggc agttcattgg gcgaagaaca agcatttcgc catctcccat
     2101 atccattggc gggaacatgt cttcttgata atgatcccag tgtccagatg ttttgtacaa
     2161 ctcaacatct cccattattg gtgtatatac atgttggtaa cctagactaa cttctttgtc
     2221 tacgatataa cgttcgatcg tgcgtcggat tgttgcccct tttggaagcc agaatggcaa
     2281 accagaacct acttctgggg aaaccatgaa caagtcaagt tcttttccta gtttacgatg
     2341 gtctctttct tttgcttctt cacggagacg gatatattct ttcaaagctt tcttgtcaaa
     2401 aaaggctgtc ccgtatacac gttgcatcat ttgattgttt gagtttccac gccaataagc
     2461 acctgccact gataataatt taaatacttg tatacggcca gtggatggaa catgtggtcc
     2521 acgacacaaa tcgatgaatt cgccttgttg ataagcagta atcacttctt cttctggcaa
     2581 ttcactaatc agttctactt tgtacggatc acttgcaaaa atttctaatg cttcctgttt
     2641 tgaaagaaca cggcgttcga tcggcagatt ttctttgacg attttcatca tttctgcttc
     2701 gattgccggc aaatcttctg cagttacttg gttttgtcca ttatctgtat cgtagtaaaa
     2761 ccctgaatcg atagctggtc caacgccaaa gtggatattt ggatagaggc gacgcatggc
     2821 ttgggccatc aaatgagctg ctgaatgacg gactaagcca agtgcatctt catggtctgg
     2881 tgtgatgatc tcaatacttg catcttcctc gattggacga gtcaaatcaa cgagttttcc
     2941 gttcacttta ccagctaaag ctttttttgc taagcttttt gaaatgcttt cagcaattgc
     3001 caatgttgtt gttccagact caaattcttt gactgcacca tctggaaaag taatttttat
     3061 cataatagtt tcctccttga aatgttttga ttgatcagat catcaagctg aaaaacaaaa
     3121 aaatcctagc atctcttgaa aagagatact aggacgaaaa gttcgtggtt ccacctaatg
     3181 ttcaaacgca aatgcgttcc tcaagcgttg taacggtccg accgcccttg cttcaacaag
     3241 ggtttcgaaa gtggtcatcc tttggttttc tcctggaaaa gtttcagcct agcttttcct
     3301 ctcttatcga agactctcaa attcagttgg ctttctcatc aatcaattat gtgtttattt
     3361 aaccactaat aaatagaaaa atcaagtggg aaactaaact tattttttcc attccccatt
     3421 tacaccgtat gttccttttt tcatctcatt gatgatgaca tggatgtgtt cttttggtgc
     3481 ctgcgtgttt ttatgaacag cttccgtgat atctttcatc atattttcta attgttccgg
     3541 actgcgacct tctactaatt cgacatgtac gaatggcata atgctctctc ctctttctga
     3601 tcgttctttt ttcaactcga ttctatcata ctatgtttgt cttgggtact gaatcaggaa
     3661 aaatggctgg atcttttttt gctctcaagg cactcaaaat agagaccgta tccacgactt
     3721 cttgcaaaac agctccgaat aatgcgggga ttagtcccgt acttgcaatt aacatcaaaa
     3781 aaatacaaat aaagatgcca atcagtacag actgtttcgc tattctcatc gtatctcttg
     3841 aaatcactac tgcttttgct acacgcaaga gatcatcttt caagatgacc gcatctgcac
     3901 tttcactagc agctgtagaa ccatgagccc ccattgcaat accgatatct gcagcagcaa
     3961 gtgctggtgc gtcattcacg ccgtctccta ccatcgcaac aggtctttga tctttaggga
     4021 tactttctaa aatggtcagt ttatcttgag gcaagctacg ggcatgtaca gaatctaatt
     4081 ggactttttc tgcaatcgtt tgagcaatgg cagatccatc cccggtgatc atcatcaaat
     4141 ttttcacatc aagttttctt agctccttga ttgtctttgc tgcttctggg cgaatctgat
     4201 ccgaaaatag gatcgttcct gcaaaagatc gatcaattgt tacatagatt gctgtattgg
     4261 acgtttctat ttcttcagct gaaacaaaag aggcacgtcc aatctttact tcatgattat
     4321 tgactactgc ttggattcct tgaccggtca cttctttcag ttgactaaca ggatacagtt
     4381 ggctgttttt cacgttgttc actaacgaac gagctaagat atggctagat tcctgttctg
     4441 cactagctgc atacagaagt agctcttctt tttttattcc attgactggc tgaatcgcct
     4501 ctacttccaa tatccctttg gtaagcgttc ctgttttatc aaaagcaatc gtttttgtac
     4561 gtgcgagctt ttcaatcgtt gttccagttt ttacaacgat cccgttttta cttgaacggc
     4621 tcattcctgc aactaaagca atgggcgcag ctagaatcag tggacaaggt gatgccacta
     4681 ccagtacctc agcaaatcgt aaagggtctt ttgagaacca ccaagaaata ccaccgatca
     4741 aataagcaat caacgtgaaa gggactgcat aacgatcagc taaacggaca aatcgggcag
     4801 gcttttcttt tgattcttcg actagtttaa taatcatttg atactggctg tctgcggcac
     4861 gtttttcagc gatcatttgg atcgatccgt ctccatttaa agaccctgac ataatctgat
     4921 ctccaggttt cttggtttcc gggcgggact cacctgtcaa agaagattca tcgaccgaag
     4981 attctccttt ggtcactcga ccatctgcgg gtacaagttc gccaggcttg actagtaact
     5041 ggtcatcaat atttatttca tcgattacta tatcctgcaa ttttccttct ttgaatcgat
     5101 gggcaattct tggggtgtta tctaacaaag actgcagttc tttacccgct cgtttattcg
     5161 cgtaatcctc tagactatct ccgcccgtaa gcatgatcaa tatcatcaaa ctagcccagt
     5221 attctttgac ggctaatgtt gcaaggattg cggtaatcgc taatacatct acgccatatc
     5281 ttcctgaacg taacgtcttg atcatttcca aaaacatcaa gaaggcgaga atccctccag
     5341 taaatgcgac aatcgcaaat gcaagggccg gctggtgaaa aacaaattca cttaataaag
     5401 ctatcccacc aataagcaaa gtaagtaaaa attttttgaa atgtgtcatt gttttttctc
     5461 ctcttttatg tgacttagag aggttagtaa taaatttcca gctgcctctt tcatcttaag
     5521 catagtcctt gactagcact ttttaaaaca ataggcctta attgaaaaca actatcacta
     5581 tcagcgtttc caaaattcat cagttctaca aacaaaaata ttcagcaagg attacttttt
     5641 cgattcatca gttaaaaagt accttttttc gaaaaactat gctatacttt taattcgtta
     5701 tttacggcgg aaggagcaaa catgcgatga atgagaaaca actagaacaa acgcacgtgg
     5761 atgaaacgat cgaactaatc cagatcgaac aaaatatgct ggatacaaaa caacaagaat
     5821 tgactcagga aatgaatcat tcgacaaaag acacagctaa tcacaagatt cgagctggtt
     5881 ccaatgaagc tttttatgaa tctgctgttg aatatcgcca acatgagcag gaattgcttt
     5941 tgaaatacca tactcttgaa gcacagcaaa aacgcctgca aacgttgtct gtcatgaaag
     6001 atagtcctta ttttgcccgt atcgacttta aagaagaccg tgaaacagaa acattatatc
     6061 taggtatcgc ttctttaaga gatctggcag aagaaacaat cgttattgac tggcgcgcac
     6121 caattgccaa tctttattat gaaggtgaga ttggtcccgc attttatgaa actgaaacag
     6181 atagaataga tgtcgatctg cagttgaaac gacaatttaa aatccaagaa ggacgtattt
     6241 tatctatggt agatacgtcg gaagtaatca atgatgactt tttgctagag atattggatg
     6301 aatcatcaag caaccatatg aaaaacatcg tctctacgat acaaaaagca caaaatgcaa
     6361 tcattcggga cacaacaagt aaagtaatgc tgattgaagg aatcgccgga agtggaaaga
     6421 catccgcttt gcttcaacgt attgcttttc tgttgtatca taatcgcaag tggctcgagg
     6481 ctgaaaacgt tcttctattt tcacccaacc atttgttttc tgattacatc tcgactgtat
     6541 tgccttcatt aggtgaaagc ggcgtgccta cacagacatt caaaaattat ttggtgcagc
     6601 tgctgccaga gttttcttta ctagatgaac agcaacaaga aagtggtttt ttgctagggg
     6661 aaaaagatcc gatacaagtg atgaaaagcg gattgacctt agtcgatcag attgatcgct
     6721 atatccaagg catcacaaac tacggtccct tgttccgtga tatgaaaata aatggccgta
     6781 cgatcctatc aaaggaatcg attcgccaat ggtataaaga aacaaatgaa caattacctt
     6841 tacatcatag actttctcta ttacaaacga agctcctgaa aaaattaggc ggtctgcaaa
     6901 aagacgaaac acgtcagcaa tgggtcaaag atctggcgga agaacagctc caagaactat
     6961 acgcaacaga tccaaatctt gaatatacag aacaaaagga gcgttcatta cgtaaaaaac
     7021 tggccaacca aatcgtacgt aaaagattcc gtcgaatcca tcgagggatc atgaattatc
     7081 aatttgtcaa tataacgaaa caatatctcc actttctaca aactgtgcca ctttctcttc
     7141 taacacgaca taaaatcagc gagaccaggt ggcaggaaca tttgacaact gttcgtacac
     7201 acttgcgtca aagagaattg cgtcaagagg atgctgtact attcttttta ctgatgcgcc
     7261 gaacatatcc agtgacggtt acacacaaag ctcgctatat ctttattgat gaaatgcagg
     7321 atttcgcacc atcacaagtg gcattgctgc aagccttgtt cccaaaagca aatttgactt
     7381 tctgtggaga tctaaatcaa aatgtctttg gaaatgaaac gatcgttgga tcattggaag
     7441 accttttcgt ggaccgtgaa gtcactcgtt tccaattaac gacaagctat cgctccacaa
     7501 aagaaatcac tgattttgct aatcatttta ttgtgaaaga acatcaagta gaaacaacag
     7561 caagaaaagg agaccttcct ttgctcatcc aaggaacaac agatgatatc aaattgaatt
     7621 ggttagcaga taccattcga acgactcagg gaaaagcccg gtattggcgt acagcaatca
     7681 tagctaaaac acaagaagaa tgcgaagctc tttatgctca actgccagac gagttgaaac
     7741 aacaagtcca gctgatttta aatgagagtg actttatgaa gcgttccatt attttacttc
     7801 cagccttttt agcaaaaggt ctggagtttg accgagtttt cttgtgggat gtagatgcag
     7861 aacatttttc ttctcagcaa gacaaattga tcctttacac catgtgtaca cgtgcgatgc
     7921 atgaattgac cctttttacc tccaataatg aaagtccttt gttaaacaat atggatattt
     7981 catcttatga gaaaaaagta ctgtaagtaa aaagacaact gctatcatta atgttagcag
     8041 ttgtcttttt atttacaata ataattgcag aaaaagtaat tcaatcattt aaggtcattt
     8101 attctatata taaatccaaa tctgtttcag gatattttaa tttgacaagc gaaataatca
     8161 ttttcagttc ttccatgttt tctggatatt ctgggtcaaa taccttgcta tgacggccaa
     8221 tcccgccatt gtcgatcaat cggtaaattc gattccattc aatgaattgg tcaattgatt
     8281 ggaaattgct gattggatag ccgccacaat ccaaaatctc tgatacacga aatgctaggt
     8341 atgcactatc gatcacttta ttttttttcg tgtctatctt ctcatttctt tcgataagaa
     8401 ttttttcagg acgatgtttc aagctccact ctaatagtag aaagaaagcc tccatccgat
     8461 actcttcttc aaataaccga aaggctgaat cagaacgacg aaaaagcagc ggaatcagat
     8521 aattttgtct ataaatcagc attggtgcgc ggtccaccat acactctaaa taacggttca
     8581 gataccctgt accgacatag tttcctaatc gatagccttc aacgccgaat cttgcgtatt
     8641 tttgcgctaa ttttgaacaa tcagttacgt tcacagctaa ctcttctact ttgcggtaac
     8701 cgcttaagat acgttcaaaa ggttctaaag tgatttttgc ttccatattc ttccccgtcc
     8761 atcttccaca tacttcatat catttcacat gatacttatg ctctcatcat accacaggtt
     8821 gaattagaaa agaaaataaa tcacacaaaa aagcaagaca atctgttagt gagattgtct
     8881 tgcttttcga aaaagactga atacttttcg ttaaaactgg ttgcttagtc ttctaatgcc
     8941 acattatgga acacatgctg tacatcttct agatcttcca gtgcatcaat cattttttca
     9001 aatgtttctt gatcttctgg agatagtgtt acctcgtttt gagggatcat ttggatctca
     9061 gcgattgaaa aatcagtgat tcctttttct tttaatgctt cttgtatact atggaaatcc
     9121 gctacttcac cgtaaacgat gatttgtcct tcttcttcca ttacatcgcg aacatcgatg
     9181 tctttttcca ttaggtattc aaggatctcg tcagcgtctt ctcctgcaaa agcaaagatt
     9241 gctgtattgt caaacatgta agaaaccgct ccggaaacac ccatgttccc gccatttttc
     9301 ccaaatgctg cccgtacgtc tgctgctgtt cgattcacat tgttcgtcaa tgtatcaaca
     9361 atcaccattg agccgcttgg tccaaatcct tcatagcgca attcagagta tgtttcatct
     9421 cctgcacctt ttgctttttc gattgctcgg tcaataatat gttttggtac attataagtt
     9481 ttagcgcgat caatgacgaa acgtagtttt tggtttgcat gcggatcagg atcacctgat
     9541 tttgctgccg cgtagatttc aatcccaaat tttgcataaa tccggctatt attagcatct
     9601 ttagcagttt tctttgctac gatatttgcc catttacgtc ccatattttc acttcgcttt
     9661 ctgatttgat agtttcataa cgcaaaaacg tcctgttcca ttatacttgt gaatcacgat
     9721 tctgtgaagc tttttttctt tcttccttca ttcttctcat ttttagtcaa ttatctatac
     9781 tcggattggg atttgcccga aattctgttc cggaatattg cctcccaatt gatagatttg
     9841 atcacttcta actaacagtt ccgcttcttg tgcctctttt tttccgattc gggaataaat
     9901 agaaatctct tttttttctt ttaagaatct tcttccagca tcggtaaatc caagtagtcg
     9961 aagataattt ttattttgtt ggacaggaat ctcttgcttt ttgatattca gcaagacata
    10021 acaagataat cgttggatcc gtgtccatgt atatcttttt gtttttacct ttgacacaaa
    10081 atcctcaaaa ctatcagcag ttgcagctgc tgttttcatg cgcgattcta ttccttcggt
    10141 catctgatag atatctgtca gttccagcaa agtagaagat aacaaccgat aacgcaaata
    10201 cggccaataa gattcccaag tctgcagcga acaagttgaa agatcttctt ctgtctgagg
    10261 cggcacaagt ccagctattc tttttccttc ttctaacgca tggcgaatgg ctgttgcact
    10321 ggctatcctc tgatctgtga tgattttttc atgatagcct gcacttttac gtcggatcgg
    10381 atgtaattcc atagggtgga catacttggc attttccttt gcataactta atcccaagat
    10441 atgatttggc gaagaaaaat caagcgtaat atcgggatac agactgcgaa aaacctcagt
    10501 cattttttgc ggataactat acgtttgatc agacagttct tgaaatgcct cttctatcct
    10561 atcttgattc tcttggacaa agcgtccgaa actgctgtaa tcaaacgaag tctcttcttc
    10621 tgttccaaaa cacaaactgt cacagtccag tgtttgcaag atttttactg cacctttagc
    10681 aaaatagtca gctgactgaa ccgcccattc gacgggaagc tccactacta aatccacacc
    10741 attttgtaaa gcttcattcg cgcgatgcca tttatcgatg atagccggtt cgcctctttg
    10801 caaaaaattc ccgctcatta cagcaatgac gacctctgct cctgttattt ttcgtgccat
    10861 ttccacatga tagcgatgtc cattgtgaaa aggattgtac tctacgataa tcccgcagct
    10921 tttcatgcgc atcctccttc atagttatcg ataaaaaaga aatagagaca agtaaaaaaa
    10981 ggcaaaaatc ggaaaaaata cccgaactat ataaactatt ctcgcaaaca caatacttct
    11041 gcgacgaaaa gctgcactgc aagagcaatg cctatatcgt tcggatatat aatttatgtt
    11101 gaagatttat tcttttcttg ttaactcgag caggcaaaac cgctagtctt tgtatgctac
    11161 aaagaaccag cgctttgatt tctctgatgc tgcttcgtct gtaaaatcag aaaatgcttc
    11221 gactttcgaa aagccgctgt tttccagcat tcttaaataa ctttccaatg gataggtacg
    11281 ctcttgatgt agttcatctt cacgaataaa tcgaccagac ccttcttgtt cttcaacgaa
    11341 aaaggtaaga aaatgttcga tgctgtgttt ctcgcttcct ggataactat cccacaaaaa
    11401 agcaaaatta tccccttgat aatgatagct atattctgga aaaacctcat ctacttgata
    11461 ggtggagtgt acgtcaaata aaaatcggcc attttcttct aacgcttgat agacttcatc
    11521 aaacacttgc tgtacctctt gtctattttt catatagcac agcgaatcag aaaaacaggt
    11581 aattgcctga tattgtccga tttctgataa atcgagcata ttgccttcca caaattggat
    11641 cgatgcgtct tcttcatatg ctcgctggct ggcaatcatc aacatctctt ctgaaaggtc
    11701 taaccctgtc actttatatc catcttttgc aaaggcaacc gctaatgctc cagtaccgca
    11761 tgccagttcc aaaatatttt ttgtgtcttc ttgtaaatga cgtttcgaaa aagctaacca
    11821 ttgctgataa agtgtttcgt ccatcacttc atcgtaaatg aaagcaaatg tttcataagc
    11881 catatgttaa tccaaccatt cactaagatc gactagcgga gcatctgacc atagtttttc
    11941 cagattatag aaatttcgtt ctggcgcatg gaaaacatgt acgatcacat ctccaagatc
    12001 gatcaatacc cattttccgc cttcttttcc ttcaatacgt tttacttcat atttgttttc
    12061 ttcttcttta tcaatgattt cttctgtaat tgcgttgatt tgacgttcgc tatttgctga
    12121 acagatcatg aaataatctg ccaacaagga aacatttcga acgtctaaag cgataatgtc
    12181 ttctgcccgt tttgaatctg ctgcttcaat cgcaattttt aattgttctt tactatctat
    12241 gatgatttcc tcctaatatg agcagcttat ttttttgcta cccagtaatt atatgtttcg
    12301 attgtttttg gataaatctg ttgttcttgc gcaagcaaat gggccaatgt atgttttgtt
    12361 tcaaatgcta cagcttcgtc tagatcagcc catgcaatgg ctcgtgcatc ttgtacccca
    12421 ggaaaatctc gacctggttc aatatagtct gctacataaa tgattttgtc aaggagactc
    12481 atcttagcag ccccagtcgt atgcacccgg attgcatgaa gaatctctgc atcggtgatt
    12541 cctaattccc gctctacaaa cgaagcgcca acaagaccat gccagattgc attattataa
    12601 ttcaataact ccggatcaaa accgtctctt acgattacca ttttgaactc ctcatctggt
    12661 cgttcttttg cataatcatg tgtcaatgca gcaatactag ctttttcagg agaagcaccg
    12721 tattttttgg caagagccac ggctgtttct tctactccaa gcacatgctt gaagcgttgt
    12781 tcgctcattc tcatctgtat tttttgcatc aggttttctc tagaataagc agtatattca
    12841 ttactatagt ccatattcat acaacccttc attttgaata taatcaatta ctttatctgg
    12901 aacaaggtag cggatagaac agccttcttt gatcttttga cgtattttcg tggaactgat
    12961 gtcgatctca ggtacatcta cccaaattac aggatatgga gtatccgttg tgtatcctgg
    13021 tcgacgtata cccacaaagt tgaccataga agtcagctca tcgattttat accattttgg
    13081 caaatattct accatatccc caccgataat aaagtaataa tctgtatccg gattgttttg
    13141 cgtcaattcc ttcatagtat cataggtgta acttttccca ccacgagcta attcaatcgt
    13201 ttcaatctgc aaaaaaggat tgtcttccac cgctaattcc aacatgttga gtcgatgttt
    13261 tgcatcaatc gtctgtttct catcaacatg aggtggctga taagaaggca tcaaaaatac
    13321 gcggtcaaga cctaaattcc ggccagcttg ttcagccatc actaaatgtg caaggtgaac
    13381 gggattgaat gttccgccca agatccctac ttgctttttc ttctctaaga attgaggcat
    13441 ttcttcagga aataattgtg aacgaacaaa tgtcttagct tgcgtattca tcatggtcac
    13501 tccttatatt gcttttactt cttttgatag cctttgatac ttttcttttg tggaaggttt
    13561 gtataataca ataacacgtc caatgatttg gacgatttcg caatctattt ctttttctaa
    13621 tacttgagct gcttcttctg caatctcatc tgtattttga agtaacgata ctttgatcag
    13681 ttctcttttt tctaaagctt cttcaatttg aacgatcatt gctgaattga tcccaccttt
    13741 tccgatttga aaaatcggct gaagatgatg cgctttgcta cgtaaaaaac gcttttgttt
    13801 tcctcttaaa ctcataattt tccttcttcc ttaaatcaat gctttgcgtt tcaatacatc
    13861 tacacccttt ggcgcccagc ccgcaattac tactggcgct gttacagtga tccagcctag
    13921 accggcaaaa acgatgtctg ttttttcttt cacagaaaac tcaaaacgaa caagctccgg
    13981 aaatgcctcg acttcatcag gacgaggagg ctgtaataat ccacctacat gtttttgata
    14041 aaattcgtct gctttttcca gtttcgttcg atgaatattt acatcatttg acacataagc
    14101 aataaatgaa gcacgattgc cgctgataaa atcaaatctt gcaagtccgc ccaagaaaag
    14161 tgtttgccct tcattcagct gataaacttt aggtttgatt tcttttaacg gtgcaatgat
    14221 ccgcaaatct tttttaccta agtagtgcgc catttgatgg cgatggataa ttcccggtgt
    14281 atcaatcaaa aaatgcccgt catctaaagg aatctcgatt ttatccaagg tcgttcctgg
    14341 aaactgcgaa gttgtgatta catcttgtac tcccgctgta tttttgatga tttgattgat
    14401 aagcgtcgat tttccgacat ttgttactcc gacgatatag acatcccgtc catcgcggta
    14461 ttcttcgatt ttttctaata gttccgtcat ctcatgagat ttcttagcac tagttaataa
    14521 tacatctact ggacgaattc ctgcttcgta agcacgttcc ttcatccatt gtgttaattt
    14581 agtttttttc aatgatttag gtaatatatc cactttgttc ccaactaaaa gtactggatt
    14641 gtcaccgaca aaacggtgta gtcctgggat tagtgaacca ttgaagtcaa aaatatccac
    14701 cacattgacg atcaatgcat ctttttgccc taattcattc agtaagcgca aaaagtcgtc
    14761 atccgtcaat gagacatctt gggtctcatt ataatggcgt aatctgaaac aacgctgaca
    14821 atagacttcc ccggaagcta aacctttttc caaagccgtt tgcggcgtgt atcctaattc
    14881 accgggtttg tttgtttgta taacggcacc acagccgata cattgtaatt cttctgtcat
    14941 tcgattccac ctcgccagcc catatcaggg tgttttgcta atagataggc cataattctt
    15001 ttttcccaaa aacgattaaa ttgtgtcttc caactatctg ttgcgataat gggttttaca
    15061 aggatgctac gtatccctgc acgattggct ccacgtatat cagtcataat ctgatcgcct
    15121 accattacta tctcatcatc tgctaaatcc aattgtttct ttgctatgtt gatccctctt
    15181 gctaaaggtt tcattgctcg tgcaacatac aaaagatcaa atttttcaat cgctcgcgcg
    15241 acacgttttg aattattgtt tgaaacaaca acaacaggga ttcctgcatt tttcatttct
    15301 aaaatccaag taagcaactc ttctgttcca tctggattat tccatgcaat caacgtattg
    15361 tctaaatcgg tcaatactgc tttgatgcct agattcttta attgggcagg tgtaatctga
    15421 tagatggctt ctaccatcca tgttggtttg taatttgaaa acatgctgtc tcctcatctg
    15481 caaaaaatga aggagcacat aaagtactcc tcaaccccgt attatactgc atatcagcaa
    15541 aaaaaactac ctctatactc gttcgtcttt cagaaaaagc atttctttac aaaatgacca
    15601 aaaataaaga ttgatcacag aaaaatttag aaacaaaaaa caactaatat tggcggaacc
    15661 tcttgtatcg tttttccagt aatttatgct gatctaatcg aacaagttcc gtcaatcttt
    15721 caatcaacgc ttttttcata atgtgtgcga ctttatatcg tggcaactgc tcgccgttga
    15781 acgtttcagg aataactcga tcaacgattc ctaactcgcg tagttctggc gcagtaattt
    15841 tcatcaactc agctgcttct gcggcgcgac taccgtcttt ccacaaaatc gacgcaaatc
    15901 cttctggaga aagcacagca taaatcgttt cttccagcat ccagacttca tccgctaaac
    15961 ctagagcaag ggcaccgcca cttccacctt caccaatgat gatggcgatg atcggtacct
    16021 ttaaatcaga catttcgagc agatttctgg caatagcctc tccttcgccg cgctcttctg
    16081 ctcctacacc gcaatatgca cctgctgtat tgatcaaggt aatcaccggt ctattgaact
    16141 tttccgcttg tttcatcagt cgtaaagctt ttcgatagcc ttcaggatgg ggagaaccaa
    16201 aatttctgcg gatattttcc tgcagatccc gtcctttttg aataccgatc actgttaccg
    16261 gtttgccatc taatcgagcg attccaccaa caatcgcttc gtcatctgca aataaacgat
    16321 caccatggca ttcctcgaaa gaatcgaaga tctcttcaaa aaaatccaag cttgtccatc
    16381 gttctttagc tcttgctaac tgaacgacat catgtgctgt cttatccacg atctatccat
    16441 cctttctgtg tatgcaattc aagaagcgta tggattttct gtttcaattc catgcgggga
    16501 acaatctgat cgacaaaacc atgagataat aagaattcag ccttttggaa atcttctgga
    16561 agttcctgct tgatcgtctg ttcgatgacg cgtcttccag caaaaccgat caagctttgg
    16621 ggttctgcta gaataatatc gccttccatt gcaaaactgg cagttactcc tccggtcgtc
    16681 gggtccgtta aaacagttag ataaaaaaga ccttcattgc tatgccgttt gacagcagca
    16741 gagatttttg ccatctgcat tagagaaaag attccttctt gcatccgtgc gccacctgaa
    16801 gctgtgaaca agacgactgg aagactttcc tttgttgctc gttcgaataa tctggtgatc
    16861 ttttctccga caatcgttcc catacttccc atgataaaat taggatccat cactccaata
    16921 atgaagggaa tcccctgaat ggttgcttta ccagtgagga ctgcttcatg aagtcctgtt
    16981 ttatcttgca tttttttaat tttttccgta tattcgggaa atgctagcgg atctttggtt
    17041 acaagatccg tatcccattc ttcaaaactt ttttcatcaa taatcaaagc tagacgctgc
    17101 catgcaccga ttcgaaaagc gtatccgcaa tgagggcata ctttttcttc accgatgtct
    17161 ttcgtataaa ggatatgttt gcaatttgga cactttgccc acatgttatc aggaacagat
    17221 ggcgagttag caggtttgct ctctctatta ggattgatcc gaatatattt ctttttctta
    17281 aacagagcca tctatgcgcc tcctatctcc gtttctggtg tccaattcgg taaaaattct
    17341 tcttgtaaaa atgctgtgct gtaatcacct gctatgactg caggatgact aatcaaatcc
    17401 atctgaaatt ctgcgttcgt gatgattcct tctgtgataa attcacttaa ggctcgctgc
    17461 atcttcatta atgcttcaaa acgcgtattt ccatggacga ttatttttgc aatcattgaa
    17521 tcataatatg gcgggatcgt atatcccggg taaactgcac tgtctactcg cagtcccatc
    17581 ccacctgctg gaagcagtaa gttttggatc ttccctggag aaggagcaaa atggaaagca
    17641 ggattttctg cattaatccg gcattcgatt gcgtgtcctt ggaatactac ttcttcttga
    17701 cacacattca aaggctcacc ggctgctatc tccacctgtt tttttactaa atcgattcct
    17761 gtgaccattt ctgttactgg atgttccact tggattcgag tattcatttc catgaaataa
    17821 aaatcgcctt cttcatccat cagaaactcg atcgttccgg cattttcata attgactgct
    17881 ttagctgctc gaacagcagc gtctcctagt gcttctcttt ttgtttgtga gatcactaca
    17941 gaaggagatt cttccagtac tttttgattg ttgcgttgta aagaacaatc tcgctcgcct
    18001 aaatgaatga catgaccaaa tcgatcacct aagatctgaa cttctatatg gcgagcagga
    18061 taaatgattt tttccaaata catatcatca tttccaaatg ccgctgctgc ttcttgctga
    18121 gctgaagaaa aatgctgtgg gagctcttct tttgattgaa ctttccgaat gcctttcccg
    18181 ccaccacctg cagctgcttt cagcatcact ggataaccaa ttctgtctgc tatttccaat
    18241 gcttcttcta ctgtagataa tacaccagta cttcctggaa tgactgggac atttgcttct
    18301 tgcatcaatt gacgcgcatt gatcttattt cccattgcat cgatcgttgc acttttagga
    18361 ccaataaatg tgatattgca ctcttcacac atggaggcaa atcggctatt ttcagataaa
    18421 aaaccaaatc ctggatgaat tgcttcggct tttgtcacga ttgcagcgct cagtacttcc
    18481 tgaacattca gatatgaatc aacggctttt gccgggccaa tgcagattgc ttcatctgct
    18541 aactgtgtat gaagtgcttc ggcatctgct tctgaatata tcgctacggt ttggatccct
    18601 agttcgcggc atgcacgaat gatacgtaca gcgatttcac cgcggttagc tatcaatact
    18661 ttagaaaaca tatttcacct atccaatcat aaaggttaat tccgcttcgg ctactttttt
    18721 accgtctact ttagcgattc ctttgcctat tccggctgaa gctttcactt tcaatatctc
    18781 aacttcaagg tataaggtat ctcccggtgt aactttctta cggaattttg ctttgtccaa
    18841 tccgccgaaa taagccgtct ttcccttgaa ttgttcaaga gaaagtaatg caactgctcc
    18901 tgcttgagcc attgcttcaa caatcaatac ccctggcata acaggttctt ctggaaaatg
    18961 tccttgaaaa aagggctcat tgatcgttac atttttctta gcaacgatcc gttctccttc
    19021 aaccatttct tccactcgat caatcaaaag cattggataa cgatgtggaa tgatttcttt
    19081 tatttcttgt atgttcattg ttttccctct ttcctgcttt gcttattttt gctgaatcct
    19141 aaagagtggc tgtccatatt cgacaactga ctcgttttct acaaggattt ctgtgatcac
    19201 tccgtcggcc tcactagtta tctcattcat cagtttcatc gcttcaataa tgcagataac
    19261 ttctcctttg gcaacttgat cacctacttt tttgaaagct ggtttgtcgg gcgctggttg
    19321 cagataaacg attcccacga ttggcgaaac aacctcgatt ccatcaaata ctgccgattc
    19381 tttttctttc attatttctg gagcagttgt tgcttgttca ggtatgacat tgactggctc
    19441 cgaaactggc aacgtttcgt ttgtttgaac catattcatg cctcgacttg ttttattttt
    19501 attcatatac aattcaaatt gaccttcacg caaatcgaat tccgttagcg aggattgatc
    19561 aaattgactg actaattctc tgatttcatt gatatccaaa attattcctc ccagcgtttc
    19621 atgcacagaa ccgcattatg tccgccaaac cctaatgaat tactcattgc ataagtaaaa
    19681 cttgcaggtt tgctttcgtt tttgacaact gtcaagtcaa tctcaggatc ttgtttttct
    19741 acattgatcg taggtgggat aaattgatgt tctaatgcca gcaaagttgc caaggcttcg
    19801 atcccgccgg ctgctcccaa taaatgtcca gtcatcgatt tcgtgctgct gacgtaagta
    19861 tctctgaaat tttcacctaa tgcgatttgg attgcttttg cttctgcctg gtcattggct
    19921 ggtgtacttg ttccgtgagc attgatatat ccgacttgtt ccggctgtac accagcttct
    19981 tccatcgcaa gcttcattgc tttagatgca ccagaaccat ctggagtagg agctgtcata
    20041 tggtaagcgt cacagtttgc accgtatcca acgatttctc catagatttt ggcaccgcga
    20101 gcttgtgcat gttctaaaga ttcaagaact agaacgcctg ctccttcacc catcacaaaa
    20161 ccattccgat tttcgtcaaa cggaatcgaa ccacgattag gatcagttga ttctgagagt
    20221 gctgttaaag ctgcaaatcc agcaatcccc atctcacaaa tcgttgcttc tgttcctcca
    20281 gcaagaatga catcagaata gccatgtttg atgttacgga atgcttcccc aattgaattc
    20341 gttccgctag cacaagctgt tacgatagct gtacaaatac cttttgcacc tacacgcaaa
    20401 gcaatatttc cagctgccat gttggcaatc gccattggta cgaacattgg agaaactcgt
    20461 tttgcacctt tttcatgtag acgaataact tggttttcga ttgttggaag accaccgatc
    20521 ccagatccga tgatgacgcc aaaccggtct tgattcattt tttctttatc taaaccgctc
    20581 atctccattg cttctaaagc agcgtagatt ccatagatcg aaaacatatc cattcgtttg
    20641 ctatcttttt taataaaata tttatcgtaa gggaaatctt tgacttcacc cgctaaggta
    20701 atccctgttt ctgaagcatc aaatttagtg atcggtgcga tgccattcgt cccctctttt
    20761 aagctattca aaaagctgtc tgcgtcattt ccaataggtg aagtgactcc atagccagta
    20821 attaccactc gattcatttg tttgctctcc ttttcttatc cgtgcatgac caatccgcca
    20881 tcgacattga tgacttgtcc ggtgatatat ggattttgtg ctaagaaaac tgctgtttgt
    20941 gcaatatctt ctacttgtcc gaaacgctgc atcggaattt gcttttccgc ttgttccttg
    21001 actttgtctg ctaaaacttc cgtcatatca gttgtgatga atcctggcgc aatggcatta
    21061 catgtaatgc ctctagttgc agcttctcgt gccacagatt ttgttaatcc tactacgcca
    21121 gctttactag ctgcataatt tgcttgacca atatttccaa tcaacccaga tacactagag
    21181 agattaatga tggccccttc tcgctgcttc atcatttttt tcaatacgtg ctgcgtcata
    21241 ttgaaggttc caatcaaatt gatatccaga cattttttga aatcttctgc atccattcgc
    21301 atcacaagtt tgtcatttgt gattccggca ttgtttacta acacatggat cgatccaagc
    21361 ttttcttctg cttctttgat catttgtccc gctttctcat aatcagagat gtcaccggaa
    21421 actcctacgc attttacacc gaatgcttcg atttcttcta tcttttcttt tggaatctct
    21481 ccgcgaccat tcaaaatgat atttgctcca gcttttgcaa aagctaaggc catcgctttg
    21541 ccgattcctc ttgtactacc tgtgataaat acattttttc cttttacatc cataacgttc
    21601 ctccttatag tattgctatt gtttcatcaa atgtctgctt attctcaaca cgcagaactg
    21661 gtattgtttt atcgattttt ttcataaatc cgcttaatac ttttccgggg ccgacttcga
    21721 tgacttgttc gatgccgatt gtttttaact tatggatact ctcatagaaa cgaacaggtt
    21781 gcatgacttg ctgttcaagt agtcccgcga ttgtttcttt cttcattatt tccgttgttg
    21841 tgttgcttat gataggaaaa gaaggttcag agaattgaat ctgacttagg tccttcgcca
    21901 gtttttttgc tgccggttct aaaatagctg tatgaaaagg cccgctgaca tttagaggga
    21961 tcattctttt gaaccctttt tcttttaata gtaaaacagc ttcgtctact gctttttctt
    22021 cgccaccaat cacgatctgc tgaggtgtat tataatttgc aggagatacg atgccgtact
    22081 tgctagcttc atgacagctt tcctcgatcg tttcaatcgg cgcattcatc actgcaacca
    22141 ttttcccgct tccagctggg gcagcttctg tcatataagc gcctcttttt gctactaacg
    22201 caactgcttc agtgaaggat agcgcattac tagctactaa tgccgaatat tctcctaaac
    22261 tcagtcctaa agctgcatct gggatgattc catgctcctt caataagcga taatacgcga
    22321 tgctgactgt tagaatagct ggctgtgtat attgcgtctg atccaaacgt tcattttctg
    22381 taaagcaaag ttcagccata tcgtagccga gaatctcact tgcttcatca aatgtctgct
    22441 ttacaacggc ttcttcatat aaatcttttc ccataccttg atattgtgca ccttggccac
    22501 taaataagaa tgctgttttc atgtttttct ccaatatatc cagaatatat gtttgattct
    22561 tcctattcaa aaaggccgag acattcctat ttcaggaaat gtcccagccc ccaacctaat
    22621 tttaatgatt atgcagtttg tttttctacg taagtcacta aatcttgaac cgttttgatt
    22681 ccgtcttctg tttcgatttt cacgtcaaat tcatcttcaa tttcattgat gatttggaat
    22741 aaatccaagc tgtcagcttc taagtcttct tggatgtcag tagtcaattt gatttcttca
    22801 gtttcttttc ctaattcttc tgcgatgatt tcttgaattt tttcgaatac cataataata
    22861 tattcctccg atattgtttg ctttttattt ttataattta acagtctaca actccatgag
    22921 aatacttccc catgttaaac ctccgccata gcctgtaaat attactttct gctgttttcc
    22981 taaggtgatc tttccactag aaactgcttc atccaataag atagggatgc ttgcagcaga
    23041 tgtattccca tatttatcca tattggtcag gaacttttct tgcggcatct ttacttttcg
    23101 ggcaattttc tcaataattc tgaggtttgc ctgatgcaaa agcagataat caactggttt
    23161 gtctttcatg acttcttgga tattgtttgc aacgtctcgt acggcaaaat caaaaatatc
    23221 tctgccagtc atttgcaaat aatacgaacc ttctgaatct tctgaataga acggattttt
    23281 attttgctgg tagccagcgg tcaatgagct acttctggta ccgtcagctg ctaatttttc
    23341 tttcagcaat tttttctgtg gattcgcttc taagagaatc ccacctgctc catcgccaaa
    23401 caacacagca gtcgtacgat cagaccaatc gattagctta gatagtgttt caccaccaat
    23461 caccagtccc ttagttgagc cgcagcggat cattttttca gccatgctta acgcataaac
    23521 aaatcctgag cacgcagcac tgatatcaaa agcgatagca tgagttgctc ccaatttccc
    23581 ttgtacttgt gctgctacag atggtgtcgt gtaatcgggc gacattgttg ctactaaaat
    23641 aaaatccaaa tctttagggt ttagattttt ctgttttatc aatttttccg ccactaaaat
    23701 gcataaatca gaagtctcct gatttgttac acatcttcgt tcacgaatac ccgtccttga
    23761 cgaaatccat tcatcagagg tatccatcat cttggaaaga tcattattag taataatctt
    23821 ttcaggaagg acgctggctg ttgcagtaat cattccaaat tgttccatta aatatcctca
    23881 cttatagtct tgcaagaagt cgtgcaagtt tttcagtgca tccagcaagg catgctgttc
    23941 ctccgtagcc attccgtcta agatgttctt gaccatttca cgatgaaaat gctgatggac
    24001 ccgaaatagt aactttcctt ttttcgttag tcccaacttt acaacgcggc ggtcatcttc
    24061 actgcggata cgttcgacat agcctttttt tactaacttg ttaatagcag tggtcaaggt
    24121 cccaacagta attgatagtt ctttggctac ttctgaagtt gtttttttct tgtacatccc
    24181 gattgcctcg atcgtgtgca tctctgtgat tgacagatct ttgaattgag attttttcag
    24241 ctcagactct tcgattgtca aaatatcatt gaagacacta acaagataat catttactgt
    24301 ttttaaatct ggttccatgt tccaccgtcc actaattagt ttgattatca aatcttttga
    24361 tgttcaaact atatcttaac ttttttcaaa atgcaacctt aaaagatcat ttttttacta
    24421 tatgagcttt ttttaagatt ttactcattt aaaacaactg ataaatcagc atttataatt
    24481 tcttttatta gaaaaatcat ctatctcaca tattttgatt atcaaagtat tttctgtgaa
    24541 cagaactata gaattcccta aaacttgtcc attatttcaa aatttgttat agtcttttta
    24601 ttcaaagcgt aaaaggagat cctatgttaa aagaaaaaat gaaaactctc cccatgctgc
    24661 cgggtgtcta tcttatgaaa gaccgagatg gtaaggtcat ctatgttggt aaagcaaaac
    24721 ggctcaaaaa tagagtaagc agctattttc atcagaataa acagcattca aaaaaagtat
    24781 tacgtatgat tcatcatata acagattttg atttcgtcgt agtagacacg gaattagatg
    24841 ctttattgct cgagtgtcaa ttgatccaac attaccgtcc tttttataac cgacaaatga
    24901 attatttcag taattataat tatgtacata ttaccaataa gggatttgta ttaacagata
    24961 ctcctacggc tcgaacatac gggccttttc gtctctataa aaaaatgccg tctattttgc
    25021 gtataatgga agaaacttat caaatgcctt ggttgtctga aattagtttg ttagctttgc
    25081 gagtccagct tcctgaccta caggaaatga cttttgaaca gaaaaaaaag gaactccaag
    25141 ggctgtttca aggccgaaat aaaaagctac tgacttactt gaaaaaaaga caacaacatt
    25201 tcatctatca gttgaatttc gaaaaagccg gtatgcttca aaaagatatc gaattagtta
    25261 cttattttat tagacggatc caggaacaaa agcagttttt aagaacacca tcgctcacct
    25321 tcagcatgcc attagcagca gatgagagtc agaaaaagca ctacctcgtt tgttatggtc
    25381 aacttgcaga aacaatgatt acctctggtg acgtttctcc tgacttctat tatgaaaaga
    25441 aagaagctca tttatctttg aaacgtcaat tgtcaaaaga agaaatcgat cctgtacaaa
    25501 tcttgatcag ttaccgcaaa aaattagaaa aagaacagtt tgaaattgaa ctgttaaaca
    25561 aaaaagaagc tgaaaagcaa ctaaattagt tgcttctcgg cttcttttag gcatcttcaa
    25621 cttcaaatgt caattatcct aaaatttatt ggattaagtc atagatttcc atcgctacga
    25681 tatcgatatt atcaaattcg tattgctgat gagtatctgt ttcagttaat tcaaatgtat
    25741 cggtcgcttt atcataagtt actgtacact tctctacgcc ttctttttca aaacggcgaa
    25801 cttgcagttc attatctgct gactcgacca tagcctccag tcgttttatg attgcgacta
    25861 attgtgaatg tgtcatcgga ggtcctcctt ttcttatttc tgttatattg tatcaaaagc
    25921 atagcctact tgcattgatt ttctctaaaa aaactcgttt tttatgattt tttttctggt
    25981 atttttcctt caggccacca aagtttgatc aaagcttggg ttccgtcatt ctcaaaacct
    26041 ttatctgcca actcttcata tagtttcaat gcttgggtag ttgctggcaa tacaagatcc
    26101 attttttctg cttcttctaa tgcaatcttt aaatctttga taaaatgttt gacaaaaaaa
    26161 ccaggtgtgt aatcttcttt taaaatacga ggagaataat tgcttaaaga ccagttagct
    26221 gcacttccac ctgaaagcgt ctcaatcact ttctttaaat caagtccgtt tttttgtgca
    26281 tagacaagca tttccgtcat tcctgtcatc gtacctgcaa tcatgatctg attagccatt
    26341 tttgtatgct gacctttccc agcagaacca tgcaatgtaa atgtcgtacc aaattctttg
    26401 aataaaggca gtacttgatc ataaacggct tcttctccac cgaccatgat cgtcagtgta
    26461 ccattctttg ctcctaagtc accaccggat accggtgcat ctaacgcatc tgcgcctttt
    26521 tcttttgctg tttttgcaat tttttctgcc aggcttggtg tacttgtagt caaatcaact
    26581 aaaatatgtc ctgagatatc tgcagaaaaa atccccgact gtccatagta gatttcttct
    26641 acatctttgg ggtaacctac cattgtaaag agaatattac tttgttctgc taccgctttt
    26701 ggtgtatctg cccagatagc tccttctgtt actaaaggat cagcttttgc ttttgtccga
    26761 ttatagacag ctacttcgtg tcctgcttct agtagatggc gtgcgacagc acttcccatg
    26821 acgcctgttc cgataaaacc aagtttcatt ttttcgacct cctaaaaatc aaaaatcctt
    26881 gcttctatgc tagtatacgc tagaaacaag gattttttca taaaaaatgt ttgaatttta
    26941 tcttttaaat gaatttaatt ttattttgat tcgttcaatc gagtcttctt cttcttttct
    27001 tcgcatctct tcttcatgat aaacaaccat gtcttgataa aattcgatca tagcttcgcc
    27061 gaaatgtgta gatgaaatat cataaagttt agcttctaaa acttttggat ctttaggaac
    27121 ttcactggaa atataatcaa taagtgctgg tgcaaagtct tcgtcggttt caaaagtttt
    27181 ccctaatgaa ggatgatcga acaatcggtt caaataagca tttccttcca cgacacaagg
    27241 tgttccggct gccatcgctt ctgtataagt aagcccttgt gtttctgaag tagaagcact
    27301 gacaaaataa tctgccgctt tataataaag tgctacatca ttgttgtcca cttctcctgt
    27361 gaactgcaca aattcttcta actgcagttc tgagatcaat tcctctaact cttctacata
    27421 aggtcctttt cctacgataa ctaatctggc gttaggataa gcggagatga cctgaggaaa
    27481 cccattaatc aaggcttgga tatttttctc ataagaaatc ctgcttaaag aaagaatcat
    27541 caaatggttt tcctgaagac ctagtgactc ccttaatttg ctgatatcct gctgagtgat
    27601 atcagaacgt ttgaattttt caatgtcgat accagtagga atcacgcgaa gcggtgctat
    27661 tacaccatag ctgcgtaatg tatcaataac acgttcactt ggacaaacta cacctgtcgt
    27721 atgatttgca aataatctag acaagtattt tacatgggat tgcctgatca cttttccttt
    27781 accgatataa tgaaggtagt cttcatacat cgtatggtaa gtatggatca gaggtatttt
    27841 caacttctta gctaccatct tcccaagtat ccctgctccg aattctgtat gggtatgaat
    27901 aagatctagt tctagttctt tggcaaccaa ataagcatac cacatgcctc taacaacaac
    27961 tcttcgatcc ttgaaagaaa taaatggtac acttggcatt cgaatcacat ctttttccaa
    28021 cttatccgca ttaggatcgg tcgttgtaaa aatatagact tcatgcccat gtctttctaa
    28081 ttcttgtttt aatgttttga tcgatgtagc aactccgctg acttgcggaa agtaggtatc
    28141 ggtaaaaaag ccgattttca tgtttttcgc ctccaaacta gtccttgacc tgatttactt
    28201 tttttaattt gctagagact ttttcattca gtacactttc gtatacattt ttaagttctt
    28261 caccgatttt attgatactt cgctcttttg ctgtttgata accggcttgt gtcgtactcg
    28321 gtagttcttg attggtaatc tgttggatca gtcggataaa ttcttcgttt gtcttcccca
    28381 tatagcagtt cttgctatct tctaaccagc cattatacac tggaatatct cgaacaagta
    28441 cgttttgttt gcttgctaaa gcttctaaaa caacgatccc ttctgtctct tcataagaag
    28501 ggaaaaagaa tagatctgca cctgaatacg caccttctat gatctctcca cgaatgtaac
    28561 caggaaacag gacattttca ggatgatctt cttttacaat tttccggatg ttccgaggaa
    28621 tcgagtacat gggaacatga ccaaaccaaa taaatgtgta ttcgggcatc ttcttagcaa
    28681 tttctacgaa atcaatgatt cctttacgtt cgaaaaacaa accgacacaa atgattactt
    28741 tttgatccgg agacagtttg aaatattctc tgaacttttg ttctttcatt ggatcagggt
    28801 gatatttctc taagtcgatc ccattggaaa tagcttgaat cggcacacgg ataccatagc
    28861 tttccaacaa ctgttttgaa taaggtgttg gcgtgatcag atagtccgct ttttggtaca
    28921 atcctaccag atattttttt acgataggag aaagctggtt cgatctgata aaggaatttc
    28981 ggaaatcttc ctctgtagaa tgcgcatgat agacaacttt ttttccttct cttctggctt
    29041 tattgaccat attatgacta ttgattccgt atgtattgat gtgcaggatg tcataatctt
    29101 ctttttcatc tagtgtataa gagataccga cttccgtcag agcacgtttt tgatgatcaa
    29161 gcgcacgccc gattccagat tttgcaagca tcttttcact ttcaaaatat aataatacct
    29221 tcaccttacg tcccccttca cttatatagt ataacatagc ctacaaactg tcactcaaac
    29281 ttaagcccta tttttgtcta ttcttactga caaaaacgtt ttcttaaaaa agaacaaaaa
    29341 aactggcgta gctcttttac aagccacacc agcttttgat acgttgttta ttttacatat
    29401 tcatgaacaa gttcaacgac ttcttccatc atatcgcatt ctttcaatgc acgatcagca
    29461 agttcagcca ttttcgctgt gtccaagcgt ttcattaaac tacgcgtttt aagaatagat
    29521 gtcgcactca ttgagaactc atctagaccc atacctacta gcaatggaac agctgtttga
    29581 tctccagcca tttctccaca catacctgcc cattttcctt cagcgtgtgc tgcatcaatt
    29641 acatttttga tcaaacgtaa aattgatggg ttatatggtt ggtacaagta agaaacgcgt
    29701 tcgttcatac ggtctgctgc cattgtgtat tgaatcaaat cgttcgtacc tacagagaag
    29761 aaatctactt cttttgcaaa cttgtctgct aagactgctg ctgctggaat ctcgatcatg
    29821 atgccgactt ggatcgtatc agatacttcc ttgccttcac ttatcaattt ttgtttttct
    29881 tcttcaaaga tcgcttttgc tgcgcggaat tctttgagtg tagctaccat agggaacatg
    29941 atacgtaaat taccatgaac agatgcacga agcaatgcac gcatttgtgt acggaacatt
    30001 tcgtcgcctt gttcagataa actgatacgc aatgcacgat atcctaagaa tggattcatt
    30061 tcatgaggta attgcagata tggtagttct ttatctccac cgatgtccat tgtacgaaca
    30121 actacaggtt ttccttccat accttctaat acagctttgt aagcttcata ttggtcatct
    30181 tctgttggga agtctggaga atccatatac aggaattcag tacggtacag accaactgct
    30241 tctccaccat tattatggac accaactaga tcttttggtg ttccgatgtt tgcagctaat
    30301 tcaaaatgct tgccgtcagc tgtgacagtt tctgcatttt ttaatttttc ccattctgct
    30361 ttttgtgctg cgtaatctgc acctgctttt tcaaattcag ctttttgttc atctgtagga
    30421 tcgatgatta catcgccttc gatcccgttg acagccaaaa tatcgccttc tttgacttta
    30481 gcagtaattt cttttgtccc aacgattgct ggaatttcta aagaacgtgc catgatagca
    30541 gaatgtgaag tacgtccacc aatgtctgtt acaaacgctt ttacaaaatt gcgatctaat
    30601 tgtgctgtat cacttggagt caagtcatgt gcaacaacga ccacttcttc gttgatcatt
    30661 gatggatttg gtaaagtaac gcctaataag tgcgctaaaa tacgtttagc aacgtcacga
    30721 atatctgcag cacgctcttg catataagca ttatcttcca ttgcttcgaa cataccgata
    30781 tacatatccg ttacttcttt tagcgctgat tcagcattta cgctgttgtc tttaatattt
    30841 tgcttgattt gacctaccat ttctggatct gaaagaacca tcaaatgggc atcaaatact
    30901 tgcgcttctg cttcacctaa gctttgcgct gctttttcac gaatttgctg caattcttca
    30961 gtagatttag ctaatgcagc atccaaacga gcttcttcag ccgcagtatc ttctactgtt
    31021 gccttactga atgttaaatc cggttgaact agcaggtaag cttttgcaac ggctacaccg
    31081 tcactagcgg caatcccttt tagcatttca accattattc agataagcct tctttcttca
    31141 ttgtttcaac gattgctgcc attgcatcag cttcgtcagc accttctgca gtaatagtaa
    31201 catcagaacc ttgacctaca cctaaagaca taacgcccat gattgatttc aagtttactg
    31261 atttaccttt atactctaag tttacatcag agttaaattt gcttgctgtt tgtactaata
    31321 gtgtagctgg acgagcgtgg atcccagttt ctgctactac gtgaaattct ttcttttcca
    31381 tattaatcgg tctcctttaa gtgagtgttg tttttatgtg agggttttct tttttagtaa
    31441 ttcagagaat cctaacaaat gccacccttt catctgtaaa gattaacatt ttttttcgtt
    31501 agatacaaca gttttcattc aatttcagat aaaagtattc aaattattcc ggattctttt
    31561 tcatcctttt cttcacattt tataacaaac gtgtttattt cctttttctt gtcgctttct
    31621 cttctcctga cgtttatcat tctttccttt gaccctcttt gttttcatat gaaacgaatt
    31681 acttgcttcc ctttttattt ttagtataat aagagtcaaa ggtcaggaat ggtcaataga
    31741 gatttcacct tttctacctc ataaatctct taaaaaacta ggggttattc ttttacctca
    31801 tgaaaaacga gatgtaaaat atggatgtac ccatttttgt gaaaggacgt gaatgattca
    31861 tgctttgtca aaactgcggc aagaatgagg caacgattca cttgtatgcc actgtcaatg
    31921 gtcagcggac acaactcgat tactgtcaga gctgttatca aaaaatcaaa aatcaacaaa
    31981 atggaggtct gactaatatg gcccaaaatg atccatttgg atttggcagt ttggacgatc
    32041 ttttccgttc catgtctcgc caaatgcaac agcaaggaaa ttatgagcaa acaccaccaa
    32101 cacaatttgg cggaaacaac aacttcaatg gtggtcagcc acctcaaggc aatacagaag
    32161 gtttattggg agaatacgga atcaatatca cagaacaagc acgacaaggt gatatcgatc
    32221 ctgtgatcgg acgcgatgac gaaatcaaac gagtcattga aattttaaat cgccgaacca
    32281 agaacaatcc tgtcttgatt ggagaaccag gtgttggtaa aacagcagtt gttgaaggtt
    32341 tagcacaaaa aatcgtagat ggtgatgtac cgcaaaaatt aatggacaaa gaagtcattc
    32401 gtttagatgt cgtatcttta gtccaaggta ctggtatacg aggacaattt gaagaacgta
    32461 tgcaaaaatt gattgaagag atccgtcaag cagaaaatgt gatcctattc atagatgaag
    32521 ttcacgaaat cgtcggtgct ggttctgctg gtgatggaaa tatggatgct ggtaatattt
    32581 taaaaccagc tttagctcga ggagaattgc aaatggttgg tgctactacc ttaaatgagt
    32641 accgcatcat cgaaaaagac gctgctttag aacgtcgtat gcaacctgta cgggtagatg
    32701 aaccaactgt cgaagaaacg atcagtattt tgaaaggttt gcaaaaacgt tatgaagact
    32761 atcatcatgt aaaatatact gatgaggcca tcgaagcagc cgcaacttta tccaatcgtt
    32821 acgtccaaga tcgcttcttg ccggataaag ccatcgattt gctagatgaa acaggttcta
    32881 agaaaaactt gacgatccaa atcgttgatc ctaaaacaat cgagaaaaaa ctgcaagaag
    32941 cagaagaaca aaaagtttta gcttctcgag aagaagattt cgaaaaagca gcttattatc
    33001 gcgatcagat caataaactt caaaaaatga aagaacgtca gctcactgaa gaggaaacac
    33061 ctgtgattac cgaaaaagat atggaaaaaa tcgttgaaca acggacaggt attccagtgg
    33121 gtgaattaaa agaaaaagaa cagacacaac tgaaaaactt agcagatgac ttgaaagctc
    33181 atgtcatcgg acaagataac gctgtagatc gagtagcgaa agcgattcgc cgaaaccgtg
    33241 ttggattaaa caaacagaat cgtccaatcg gctccttctt atttgttgga ccaactggtg
    33301 taggtaaaac agagcttgcg aaacaacttg cctacgaact attcggttca caagattcaa
    33361 tgattcgttt cgatatgtct gaatatatgg aaaaacatag tgtctctaaa ttgattggtt
    33421 ctcctccagg ttatgtcgga tacgaagaag ctggtcaatt aacagaaaaa gtacggagaa
    33481 atccttacag tcttgtcttg ttagatgaag tagaaaaagc tcatccagat gttttgcata
    33541 tgttcttgca aatcttagat gatggtcgat tgacagatgc acaaggaaga acggtcagct
    33601 ttaaagatac gatcatcatt atgacaagta atgccggaac tggtaaagta gaagcaaacg
    33661 ttggttttgg tgcggcacgc gaaggtgtta ctcgttctgt attgaaccaa ttaaacaact
    33721 actttacacc agaatttctg aaccgttttg acgggatcat cgaattcagt gcattatcaa
    33781 aagaaaactt gatgacaatc gtcacactaa tgctagacga tgtcaaccaa atgctggcag
    33841 cacagcaact tcacatcgaa gttcctacga atgtcaaaga aaaattagtt gacttaggct
    33901 atgatccatc tatgggtgct cgtcctcttc gacgcacgat ccaagaacaa atcgaagatg
    33961 gtatcgctga attttatctt gatcaccctt ctatccatga gttgaaagca aaactggata
    34021 aagatggaaa aatcatcgtt acttctaaac cagaacgttt ggctaaagaa tcagccgaag
    34081 aaacggctga ataaatccag ttttatagcg tgagacggta tttctttgag aaatgccgtc
    34141 tcattctttt ttcagaaaag tcaaaatact gttcatttta taaaaaagaa attataataa
    34201 gagaaacaag caattaaaaa tacataaaag aggtgagcgc catgaaattg gtaaatgtaa
    34261 caaacagcca ttcccgtctt gtattaaacc agcttgaaaa cactgatgcc catctagtca
    34321 aggtctacac agccggaaat accactattg tctacactga agcccctgaa cataatgaaa
    34381 ttctgctgat caatgacaaa cgtaaaatcc agccgaaaga aatcgaagat gctaaaaatt
    34441 atttcttaga taaaatcaaa gacgccgttt accacgagga tgaaatcaaa gtaatcgaat
    34501 tggcaggcct tgttgaaatc tcgattccaa aacatgaatt aggcgctaca ttagccgtgt
    34561 aaacaaattt tgaacataat aattaaagag cgtgggacaa aagtaaagaa cacttttgtc
    34621 tcacgctcta aacacgtata aacggcgaaa gcagaagcaa ctccttcgga aataagctga
    34681 aattcacgaa aattgctttt caaatttttg tgaattccag cttatttctt ggagttaaac
    34741 gcttctgtct cagcctcttt ttctttctag ctttttgatt tttctctttt cttttgtact
    34801 tttctctttt cattttcagt tctacgcgtg tctttatttt taactttttc ctctttatgg
    34861 atgattgatc gtactttttg tgcaatttgc tcgtttttgt cccagtcttt tacatctaat
    34921 aatcgacata atcgtaacat ctcttctttt ttctgttttt ttctttcacg tctttgccat
    34981 tctgtttcca tgtgtcacac tctcctttct ttaatcatat gtacgcaaaa taatttttat
    35041 atttttttga ttagacattt ctatgatttt aatatagtaa aaagagccgt cacggaaaat
    35101 ccgtcacggc tctaaacaaa atatgagagg ctgtttttgt ttggctattc ttattacttg
    35161 atgcagggca gcttgtgtca agacttcttt acatcaaact ttttaatttt acattgggat
    35221 atttatccgc aaaccagcgt tctgcaaatt ggttctcgaa taagaacaac ggttggtcga
    35281 aacggtcacg agccaagata ttgcgacttg aactcatctt ctcatccaaa tcttctggat
    35341 cgatccagcg agcgattttg tgtcccattg gagacatgat tacttcggcg ttatactcat
    35401 ttaacatacg atattggaat acttcgaatt gtagctgacc aacagctcca atgatatatt
    35461 cttccgttag atatgtttta taaagctgaa tcgctccttc ttgaactaat tgatagattc
    35521 ctttgtggaa ggatttttgt ttcatgacat tttttgcagt cactttcata aacagctctg
    35581 gagtaaatga agggagttct tcataagcaa cttttagttt tccttcgaac aatgtatccc
    35641 caatctgata attgcctgta tcatatacac cgatgatatc gcctgctact gctttttcga
    35701 cgttttctct cgaatctgcc ataaattgtg tgacattgct taatttcagt tttttatttg
    35761 tacgttccaa ccagacatcc attcctcgtt cgaatgttcc agaacagatt cggacaaaag
    35821 cgattcggtc acgatgggct ggattcatat ttgcttggat cttgaatacg aaacctgaaa
    35881 attcttcctc ataaggactt accatctgat catcttgtgt tttgtgtcca taaggagctg
    35941 gtgccaattc aacgaaagtc tctaaaaaag tctgtacacc gaagttagtc aatgcagaac
    36001 caaaaaatac tggtgtctga tcgccacgag caattttttc ttgattaaat gcatctccag
    36061 cctctttgat tagttctact tcttctaaga cttgttcata taaggaattt tcagttagag
    36121 gatgattttc gggaagcagt ccatcttcat ccaattctac taatcgttca tcctgataat
    36181 tttccggacg ataaaactct acacgattat ggtagatatc ataaagacct tctagccctt
    36241 tacccatacc gattggccaa ttcatcggat aagattcgat atctaatagc tcttctaatt
    36301 cttctaacaa ttccaatggt tcacgaccat cacgatctag tttgttgata aaagtaaata
    36361 tcgggatgcc acgttttttt acaacttgga ataatttctt tgtctgtgct tcgatccctt
    36421 ttgcactatc gattaccatg accgcactat ccacggccat caaagtacga taagtatctt
    36481 cagaaaaatc ttcatgtcct ggtgtatcca agatatttac tcgtttccct tgataatcaa
    36541 actgcataac agaactagta acagaaatcc cacgttgttt ctcgatttcc atccagtctg
    36601 atttggcaaa attacctgtt tttttgcctt ttacggtccc ggcttgacgg atagccccac
    36661 caaacaatag taattgttct gtaatcgttg ttttcccagc atccggatgg gaaatgatcg
    36721 caaaagttct gcgattgtcc acttgttgct ttaattttgg attattcata acctaactcc
    36781 atttcttcca ttcaattatt tatattttct ctaggcacag attgtccgat ctcttaaaga
    36841 aagacaattt catatagggc tgtgacaaaa gccgtgtagc agtctctttt tccgagtaaa
    36901 cggcgttcta gagacagcct atcagcaata agcccaccca agccaaaaat acgaaaagct
    36961 gtttttgctt ggctgctctt attacttaat gcaggatagc tttttcacaa cctttgtcaa
    37021 ctactacaac tgaatcagta tagcatggat tcagcgaatg aaaaagccac caaaccataa
    37081 gagtcaaata tttttttgtc agctgactaa aagaaaagac gtgttgcttg tttattcaag
    37141 caacacgtct ttcataacca agtttccaat tatcttcttg gctcgtcatc ttcgaattct
    37201 tttctgaagt atcttcgttc ttcttcaggt tccgcttctg tttcttccgg atcatgaaaa
    37261 atgacacgga ttttaaggat tcgagaacct tccatttctt cagaaaccag cgtaatatta
    37321 tcgacatcaa acgataactt ttcgccttca tccggaatca tgcctaatgc tgtaatcaaa
    37381 taaccagcca tcgtatctac atcactcata tgcagatcac tgtcaaaagc ttcattgaac
    37441 tcatcaatca gcatacgtcc ttggatgata tattcgtgtt catcgatttt ttcataaaga
    37501 ttctcaactt catctgattc atcatcgatt tctccgacga tttcttctaa aaggtcttct
    37561 agtgttgcta acccaacgac gccgccatat tcatctaata aaatagccat ctgattctgc
    37621 gtctttttca tttcatataa cagatcatca ataaagaccg tttcaggaac gaataaaggc
    37681 tcctgcatga ttttcttgat atctaaatta tcaaagccga atttatgggc agcttttagt
    37741 aaattctttg tatgaaggat tccgactact ttatctttgt cttcgttata aacagggatt
    37801 cttgaatagt tttcggataa aacttcattc acattttctt ccacagtgtc gttgatatca
    37861 atcataaatg catccgttcg tgggaccatg acttctcggg caactttcgt atcaagagaa
    37921 aaaacccctt ggagcatttc taattcttca ttattcaata cgccttcgtt ttcaagcata
    37981 taacgcattt catctctggt catttttgaa tcttcatcat caaaagtcat cggcgtgata
    38041 cgcgccaata aacttgtgga agcagaaagc agccagacga agggcttagc tactacacca
    38101 atcaagcgta tcagccctga agtgaacttt gcgacttctt ctgatttatt taaagcaata
    38161 cgtttagggt acaattctcc aaaaacaatc gatacatagg tcaaaatagc cagcacaatg
    38221 atatttgcaa tattttttgc cgctgtgccg ccacctaata ccggagctaa ccgttccgat
    38281 aaagtattag ctagtgaagc accagacaaa atgttgacca aagtgattcc tacttggatt
    38341 gtcgatagga aattatttgg attctgcaat atttttaaaa gcttttgaga tttcacatct
    38401 ccttcatcag ctttttgctc gattcgattc ttattgatcg aaacaacagc aatttcggaa
    38461 gctgctaaaa aagcattgat caatgtcaaa acgatcaata ataaaatctg cgctaacagc
    38521 gactgactct cagggtcagc attcataatc gcattctctc cttataaaat taatttttag
    38581 tttacgatag aaaaaaacgt ggcactatag ccacgttaaa atggtatcac aaagcaattt
    38641 tctttgcaat aaaaacaagt gtactaaaac tacctacgag gtcgtagcaa ttttcttctt
    38701 gttttcattt tgcttgtctt ctttgacgat tttgattata taggaaatga tcgtcttgca
    38761 gattgcgtaa aaaggaacac ctaagaagat accaagcaat ccggcaatat ttccagctac
    38821 tagaagaacg ataatgatcg ttaatggatg gattttcagt gatttcccaa ttacattagg
    38881 ataaatgata ttcccatcca actgttggac gattagcaca accacacaac aaagtaatgc
    38941 ttttaccgga tcattgaaga ctgttactag aaatgcaggt gctagtccta gataaggtcc
    39001 taaatatgga attaggtttg tcaatcccgc aatgacccca aataagaaag cataatccac
    39061 accaattacc atatatccta aaaatgtgaa ggtaccaacg aataaacatt cgattgcttg
    39121 tccgctaatg taattagcca atgttttatt cagttgcccc aataactcca caatttggtt
    39181 tcttcttttt tctgggaaaa actgttggat gtttggcact agtttttctc cgtctttcaa
    39241 catatagaac aagatgaatg gtgctgtaat gattactacg gttgccgaag cgatcgttcc
    39301 aacgatcgaa cctaaactat tggatactcc actaaggaat tgctgaatga ttgtcccgta
    39361 agaaatgtct aattgctcaa aatatttatt gatatctact tccttgaaca aaggcaattc
    39421 ggctacctct tttaaccagc tttctacctg tttgatgaaa tcaggcatat tagatgccaa
    39481 tgaggaaatt tgctgtacta gacttgggat gacactaagt aaaatccaaa taattgctgc
    39541 aactaaaagg agcagcacaa ttgcgacagc ccatattctt ttgatttttg ctttcatcaa
    39601 cagcttgaca ataggattca ataaatagta aagaaagcct gcaatcagta caggtgcaaa
    39661 taacgtggaa aaaaatgtcc cgatcggttc gaaaataaag tttatttctg atgaaatcat
    39721 gatcaatgca gctatgatca ataattcaag cgaccaaaac attagtttag actgtctaag
    39781 tttttcaaac aatagatttc ctcctttctt tcttactagt atatattata ttcgttaaaa
    39841 attcttttat tcttttttta tttttgaaaa cttgccatac tttttatttg ttttattttc
    39901 cagtatacta tacgaaagga aggtggctag accatgaaag ttgtacaaac aaaagataca
    39961 atgagcaata tttacttaga tgctgtacgg atcaggcatc aagtttttgt agtcgaacag
    40021 ggtgtgcctt tgtctcgaga aatagacaaa gatgaagccc attgtatcca cttcgtcctg
    40081 tactcagata aaaaagaacc gcaaggaact gtacgtcttt tgcctttaga aaacggaaaa
    40141 atgaaattac agcggatggc gattctttct gaatacagac accaagggtt aggaaaaata
    40201 ttgattgaag aagcagaaaa ctttgctaag aatcaaggct ataatacgat tttattaggg
    40261 gcacagtcca cagctgaaac tttttacgaa aaactaggat atacagctta cggcgatcct
    40321 tttgaagatg ctggcatgcc tcatatttat atgaaaaaga ctttataaaa atttatttcg
    40381 aaaaaagcaa aaaacagcaa gcttttgaga aaaatctctc actggcttac tgttcttttt
    40441 tgtgtttact tacgcgacaa ttgcttgtaa cggttatacc aaatatcaat atagccttcc
    40501 gagaacgggc catctccatt attgatccag tcaaccagaa tcttcacatt ttcttttagg
    40561 atgaagtcaa tatcgttcgg gtaattcatc attttgctgt gcatctcata ttcatcgaca
    40621 tccaatagtc gtttctcgcc gtcaggaaat accttgatat ccaagtcata gtcgatatat
    40681 ttcaaggcct catcgtccag caaaaaaggt gaagctagat tacaataata ggaaaccccc
    40741 ttttctctga tcattgctat tacattgaac cagtattttt tatgaaaata aacaatcgct
    40801 ggttcgcgcg ttacccatcg gcgtccatca gattcagtga ctaatgtgtg atcattcacg
    40861 ccgatcatag agtgttcgct tgtttttaat accatggtat ctcgccacgt tcgatgcaat
    40921 ttgccgtcgt gcttgtaact ttggatcgtc acaaactctc cttcttttgg aactcccata
    40981 gcaacccttc cttaagcagc attttgtgct ttgtgtttgg gtgttcatta caccgacatc
    41041 ataattatta tatcaataaa aatgagcttt gcctagaaag gattcctatt gtttcgattt
    41101 ttctctaact gatctaccag tttcatttgg accttaggaa aaacgaccga atcaaatgca
    41161 tcaggcttca accacttcga agttttgttc tcggtaaatt cttgttctgc tccctcggtt
    41221 gcccgtccgt aaaaaaggag aacatgccat ttcagatgac taaaaatatg agtaacttct
    41281 cctaaatgtc gtgtctgcca aacaaagagt tcctgctttt caaatgggag attttgctct
    41341 tcttctgcta ctaggtcatc aaacagatcg atttctggct ttgtttccca ttcttttttc
    41401 aatcgctcat actcctcttg tgtcacttcc atcattggaa atgtccacat attcgccagc
    41461 aatttttggc tatctctttc ttcaaaataa tacgctccag aatgattttg aagagctgca
    41521 ctgatataat aaacgtcttt tggctttgct ttttttgttt ttacaggaaa actcgtttgg
    41581 attcctcgtt tgttagctaa acaaaaggct tggatcggac aagtctcaca ctttggagaa
    41641 gttggtgtac agatagctga acctagatcc atcattgctt ggttgaattc acctggatgc
    41701 ttttcatcaa tgattttccg catcgcttca tcaaagattt tcctgctaga agcttttgcg
    41761 atgtctgctt caatgcaaaa caatctgctg actactcgca tcacgttgcc gtcaactgca
    41821 ggttctggaa gtccaaatgc gatacttgca atcgcgcctg tcgtatatgg tcctattccc
    41881 ttcaatgagc taatttcttc aggcgtttgc ggcatttccc catcaaattc tgacatgatc
    41941 tgtttagcag cagcttggat gttccgggct cttgagtaat aaccaaggcc ctcccatgct
    42001 tttaaaagct tttcttctgg agcatttgct agctcttcaa ttgtaggaaa ccattccatg
    42061 aaacgataaa aataatcgat cactgtgtct actctggttt gctgaagcat gatctcagag
    42121 atccagatac gataaggatc acgattatag cgccaaggca ggtttctttt ttcttgttca
    42181 taccattgaa tgaactgatc ttgaaattct tttgtttctt tatctgtcca tttttcccat
    42241 tctttattca ctttcctctt ccttttccgt aatgaatcgc tggatcatat ccaaatcaaa
    42301 tcctttttga tataagcttt gctttacttt tagatttctt tttttaggtt caaaccttaa
    42361 atttcttcgc catagtttat ctccttgttt gactaaataa tcatattcta tttcttgatc
    42421 tgcttcttgc ggaagatcag ctatcgcttg ttggatcact tcttgagaaa agcctttcgt
    42481 catcaatgtt tgttggattt ttctcaataa ttctttttgg ctttttccgt gattttttcc
    42541 aaacgctttt tcggctgtct gatgtgcatt ttgaacttgg tcttcaaatg tatattggct
    42601 gagcgcttgt tcaatgattt caggtttcaa acctttttgc tgcatctgct gcgctaattt
    42661 ctttggtcct ttgtcactta agcgcatatt cgtgcgcaca taactttccc catagaccaa
    42721 atcatcgaca aggtccaatt cttttaagcg ggctacgatt ttatttcgat cttcttgaag
    42781 gatttccttt tcttttaagt atgttcggat ttctttttcc gatcgcaact gataacttaa
    42841 gtaattcatt gctaggtgaa aaccgaaatc agctccgcta ctcttcttga tctcttggat
    42901 agtttcttcg tctaattccc gtccttttaa taatcgatag cgtactaata catcttcaga
    42961 tacttgtaaa gcttctcctt cagataaatc tacgcgatag aaagggcctt tgcctttact
    43021 gattctcgta acggttaaca taaacatcct cctcgaacat atattctcta tcataccaca
    43081 gaaaatcccc gtaatcaggt attatatgtt agaataaacc acagaaaaaa gaaaaaggga
    43141 gatacttatg gcagaaacaa ttgtcaaaac tggacaaacg gttcctttga aaatcaagcg
    43201 tttaggcata aatggtgaag gaatcggtta tttcaaacgg ttgatcatat ttgttccata
    43261 tgcactacca aaagaagaag tactagtgaa aatcacgaaa gcaactcctc gctatgcaga
    43321 aggagaatta ataaaagtca aaaaaacaag caaagatcgc gtagtggcac catgtcctgt
    43381 ttactatgaa tgcggtggct gtcaattaca acacttagct tatcaagctc aattggattt
    43441 taaaaaggat ctgcttttgc aagcattgga aaaattcaaa ccagcaggct ttcgatctta
    43501 tcaacttttg ccgacgatcg ggatggatga gccttggcat tatagaaaca aagcacaatt
    43561 tcagttacga aaaaataagc agactcaaaa aattgaagct ggtttatacg aagcaaactc
    43621 tcatcagtta gtccctataa cagactgctt ggttcaagaa cctcgaacac aaaaagtaat
    43681 gaatactgtt gttcaactat tgaataaatt tgatgcaccc atctatgatg aacggacaaa
    43741 cagtggaatc ttccgcacaa tcatggttag aatcggtgtt aaaactgggg agttacaagt
    43801 tgtttttatt actcgcagta aaaaattccc gcaaaaaaac gcaatgatcc gtgagatcaa
    43861 tgaacgactg cccgaagttg tttcaatcat gcaaaatgtc caggcacaaa aaacgtctct
    43921 cgtgatgggg gatgaaacga tccacttatg gggaaaagaa gccattgaag aacaaatcaa
    43981 tgaagtgact ttcgatcttt ctcctcgtgc cttctttcaa ctcaatcctc agcagaccga
    44041 attgctttat ggcgaaggaa tcaaagcatt agatgtccag cctaatgaaa cgatcgtgga
    44101 tgcttattgc ggagttggga cgatcggctt aagtgtagca aaacaagcca aagaagtacg
    44161 gggaatggat accgttcctc aagcaatcgc tgatgcaaaa aaaaatgcgg aaagattagg
    44221 atatcacaac actcgatatg aagtcgggac agcagagcaa gttctgccta aatggttgaa
    44281 tgaaggtttt cagcctgatg gtatcatcgt agatccacca cgtacgggtt tggataacgc
    44341 attgatccaa tcattattga aataccctcc aaaaaaactt gtttatatct cctgtaatgt
    44401 ttctacactt gccagagatc tggttaattt aagtaaaaag ttcaagattg aatatttaca
    44461 gtccgtcgac atgtttcctc agactgcacg ttgtgaagtt gtcgtgaaga tgacgagact
    44521 cgctgactaa atgaaagagg ttgtgaaaaa gtctgccctg tatcaagtaa taagaacagc
    44581 caaacaaaaa tagctcttca tgttttatga atactgtact tgtgaccgaa gagttaacag
    44641 gaggacacta tttatttaaa aaaagggttg tgacatagtt tttgtcacag ccctttttga
    44701 ttattattgg atattcacgt ctatcacttg ataaaatgca tttgtcgtat cgctgatatt
    44761 ccatactgct aaaatcacat tatatccttt tcgatcctgc ggaagtgtga tcgtttggtt
    44821 gactgttttt ggtggaacag ttgctttgtc gtctattttt gtgatcaatt caaaatcact
    44881 aaatttcaaa ggttgattag gattccaagt tggtttggta atgtagtaat cccaagtact
    44941 tgtccgatgt tgtgctgtta aattccaagt aatatttaat gttcctggat taaccatgtt
    45001 tttatgccat ctgttagatg tctgttcatc taaaggctca aagccgctga ctcctgcact
    45061 agcaattttt ccatcaatga atgtattttt ggtagcttcg atactttgcg gttcccattg
    45121 tgctcttccg acattttgat ttaagtttcc tgctgctgat gttcctaggt atgcacggct
    45181 tcctggagaa gtaatataac catgcgcaaa acctggaatg ctaaaaccga acaaccctaa
    45241 actaactaac ccaataaaca ataacgtact aatctttttc atgtagaaac ctccttcatt
    45301 tgataaccac attgtaaacg ctttattgta ttaacacaaa cattatgctt ttataatttt
    45361 atgttgaagt aaaaaaggtg aaaaaagtaa gatgcagatt ataacagaag tagacgagaa
    45421 aagtacaaat agaaaacatg agaatcaaat catatgatct ttttcaaaaa catcattcat
    45481 ataaacaaat gttcaacttt ttaataacaa caattatcaa tttttttctt acttcacaaa
    45541 ctaaatacag gtcttgctgt gagccttcat ggtaaactaa tattatagaa aggagttagt
    45601 aaaatgaaga tgataaaaga tattcgtttt tgggtttgtg ttataggaat tgtcatatta
    45661 ggctttttat cagggttgct tagcggaaat cccggaaaat attactattc tttgcaactt
    45721 ccaccatttg caccacctag ctggatattt gggccgatgt ggaccttact gtatatattg
    45781 atgggtattt ctctttattt gttacttaat cacaacaaca aaaaacagcg aaacaatctt
    45841 gtcggtcttt ttgtgattca gttcattttt aattttatat ggtctgctct attttttaat
    45901 ttaagaaata ttttcattgc agcaatcgat attacacttt tagttatttt cttgtcagtg
    45961 cttatgtatc agttgtggct gcatcatcgc ctggcaatgt ggctcatgat tccttattat
    46021 ttatgggtac tattcgcaac tctattgaat tattcaattt attttttaaa ctaagcgcta
    46081 aaaagagacg tcctgtaatt taacacatag aaaaagtgcc acctaagtta gattttttgt
    46141 ctaatttagg tggcactctt tattaaccaa actatttttt tctagtaccc acttgttgtt
    46201 ccatactcat tattctggtc ataaccataa ccattttgtt cctgtccagc gtaaggatca
    46261 taactttgag tatcttgact tggtgtatag tactgacttg tatcttctgt ttgctgataa
    46321 taggtattcg gatcttggta ctgatcatat gtgttttctg aataggaaga ataatcggtg
    46381 tacccttcac tattcgatcc atcaccgttt gtcgaatcgc catcttccga atcatcaaag
    46441 aacatcattg aagcattctc atttttcaaa ttaggtaatg tatcgcttgt ttttatattt
    46501 aattgtttct tcagttcatt ttggatcgaa agaagatcat tttttcctaa aatttgatag
    46561 tagatatcat tgatcatttg tccttcgcct tgcaactggt cttgtttgat tgtttcaaac
    46621 gccggggtgt agttcgtcgc tacatcaagc atgtcatccc aatctaagtc cgtcgtcaca
    46681 ttgttctcaa ctgcttttaa aatttttcta taattgctta cgccatctaa acttaaaact
    46741 ttattgacga ttttcgtcac tacttcccgc tgacgacgtt gtcgaccgat atcgccttct
    46801 ggatcttcgt gtcgcattcg agaataggct aaaccttttt ctccattcaa tgtttgttca
    46861 cctactggta catggacacc atccaaagta aagtcaattt tattattcac tttgatgcca
    46921 ccgaccgcat tgatcaaatc ttccatgcca tccaaattga tcgttacata atgatcaata
    46981 ggaatatcga gcagttgctc aattgaatcc atggccattt cgacaccacc aaatgcgtag
    47041 gcatgattta atttatctac cgttccataa cctacgatat tcgtataaat atctcggtcc
    47101 aaactgatga tcgttgattt tttttgtttc ggattaactg ttactaccat catcgtatca
    47161 gaacgtcctt gttccgttct tcctaatcca ccggtatcta aacctaatag caaaaccgaa
    47221 aaaggttctt tgtcatcaat gcttactctc tcagaacgtt tggaggatat tcgattagag
    47281 tttttagaaa ttttgtttac tgtttggctc gcttctccca taaatctgat tccgtatgct
    47341 gataatccgg caatcagcaa aacgaatacc cctaacaagg ttaatagaac tttttgccat
    47401 cgcttcataa tacacctctg tttcacattt tctaaaatat tgtctcatat aactgttcaa
    47461 tcagcaaatt cactttttaa tcataagaaa actttaaaaa acatttttgt gtaacgatta
    47521 ttatttttta aaatttctca aaattcttaa ctatcatacc ataccgtgaa aaagatcgaa
    47581 agaccgaata cacgcagttc gcaatcgttt tatctttttt tatgtatttt ttccagaaaa
    47641 agcgaacaac aaggtatttt ccaaataatc gtgcagtaaa atgatcgcac atacctttcc
    47701 catcttttta acagtctttg cctaccgttc agattatcat tcgatttcac gacaatttct
    47761 tcctatgact ggtccttttg ttaaacccat cttctattcg ttttatttcc agctcactgc
    47821 atggctctta aaatgactcg aactagtgat tgcattacca tcatctttta atggatagat
    47881 atgctcctct tcaaagtaaa acgattttct tttaaagtaa tagaattgac atggtaatga
    47941 gtatgtatac tagtggtttc acaaatggtc ttttattcaa catccaaaaa ctgaaatttc
    48001 tttaaaatcc attactaacg aagaaaatgt tccttgcttg ataattagtt aggacatgtc
    48061 aagtgaacaa atgcatttac ttagccaaaa aatctaaaaa cttcataaat agacaaaaag
    48121 acacgactct ctaagaagtc gtgtctttat tcaacaaatt attataattt agtcacttca
    48181 gcagcttgag gtccgcgtgc accttcaaca atcgtgaatt ctacttcttg accttcttct
    48241 aggctcttga agccgtctcc ttgaattgct gagaaatgaa caaatacgtc atctccgccg
    48301 tctactgtaa taaacccaaa tcctttttca ttgttgaacc atttaaccgt tccgtgttcc
    48361 ataaatgtat atcctccaaa aaagttcttg caagtaacct tgcaagaaca ttatacccaa
    48421 tttagaaaac gctagcaagc tttcgctctt ttattttcca aattattttt aagactgata
    48481 tgacggagga aatggttatt ttgctgcttc gaaacgtttg tttacttcat cccaattaat
    48541 aacattccag aatgctgcaa tataatctgg tcggacattt ttatatttca aataataagc
    48601 atgttcccaa acgtccaaac ctagaattgg tgtctttcct tccatcaatg gagaatcttg
    48661 atttgcagta gaggtaatag ctaattttcc attttccatt acaagccaag cccatccaga
    48721 accaaatcgt ccagcggctg cttttttgaa ttcttcttta aaagaagaaa aatcaccaaa
    48781 agcttcatta atcgcttctt ttatttctcc tgtaggttcg ccaccagcat ttggtgccat
    48841 gatttcccag aaaaatgaat ggttagcatg tccgccacca ttgttacgta cagctgtctt
    48901 gatatctgtt ggaatagcgt ccatatcaga taataattct tctattgttt tttcgcctaa
    48961 ttctgggtat ttctcaattg ctgaatttaa attcgtcaca taagtattgt gatgcttatc
    49021 atgatgcaga tgcatcgttt cttcgtcaat ataaggttcc aatgcgtcat atgcataagg
    49081 tagatctggt aatgtgtaag tcataaaaaa attcctcctc aatgttttct taataatgtc
    49141 tacattacaa agagtaacaa agagaaggaa attcttcaat tgttatgcct agtcgtcttt
    49201 ttcactttga cctacttctt cttcaaaaac ctcagtttct ttaaaaataa acaacttgct
    49261 gaaaatatag ttcgcaagga taacaataat ttgagtgatg attttcgcca catactcatt
    49321 gctgttcata acattgatca acaataccat tgcccccatg tccaatccgt aagaaaggat
    49381 acggtagaag aagaacttac cgcattcaat aagtgcatgt gtaaaattcg gtgattttga
    49441 atggaatacc caaagtttgt tcgttacaaa agcaaacaat acagaacaaa accacgaaat
    49501 agaattggat aaggccatac ttaaatcaaa atattggcgt gcgagagcaa aactaacaaa
    49561 atttacaatc gtagccaaac caccaaaaaa gagatagact agtatctccc aatatccttt
    49621 tgcttctaaa tatcctttta actgtcgata ctgcttcatg agccaaccta ccttattaaa
    49681 aattcttatt tatcatactc tatatttcaa taactttcat ctttatttaa aaaaattaat
    49741 tttttttgat cctttgcctt tgtctctgct tggatcgtca catgtgtaat accatatttt
    49801 aattttaata aagaaattat acgaggatat atcttttcaa tctcgcttag tagctgatct
    49861 tcaaaatcaa tatgtccgtc gaaaataatt atcttttcgc tatactgcca aatatggaca
    49921 tgatgaacat cctttacccc atcgattgct tcaatttctt gttccatttt ttcatagtcg
    49981 atagcaggtg cactttgtat caaaatagcg gcagcttttt tgatcaccat tatcgcttct
    50041 atcaatatat atatcgaaat gatcagtgta ataactggat cgatccagta gatatcgaaa
    50101 aaacggatca aaattgctcc gataatcaca cttaccgaag acagtgtatc acttaacaaa
    50161 tgcaaataac tagattttat attcaaactt tcatctgctt cttgtcgtaa taataatact
    50221 gagaacaaat tcgcgagcaa tccaataact gctactgtta gcatcaaatg actatttatc
    50281 ttttctggtg aagtgaaccg cttgaatgct tcaacggtta aaaacaagga taatatgatc
    50341 aatatgaatg agttgatgaa agcactcaat atttctaaac gctggtagcc atacgtacgt
    50401 tttttatttg cttcttttcg ggccattttt tgtgccccgt aagaaaaaat aattgccaat
    50461 gtatcactaa ggttatggaa agcatctgaa acaagagaca aactccctga cataatccct
    50521 ccaataaatt ctgataaagt gatcaccgca ttcaaaacca ctactccaaa tagttttttt
    50581 gatgatctct gtggctgtgt aggcactatt ccttcctcca ttttatttat attggatagt
    50641 ctttagacaa gaataacatt tttttgatat ttcaccaatc attcagctgt ttccttaaag
    50701 cacttgtatt tcacttgata cttcgctaga attgcaagtg atgacactac tagatgagga
    50761 gtacttatga caacaaaaca attaattatc agttccttta tacgattcaa agacctaaag
    50821 gaggcgagaa atgtcccatt ttggaaagcc attgtctatc ttttagtttt gagtataatt
    50881 atggctttgc caatctcttt tcaagttttt caagtcttaa acaacattca attggatggg
    50941 caaaagattg ctactcgcat tcctgatttt acaatccaaa acgggcagct tcaaaccgaa
    51001 gaaaaagaag gattcattta ccaaacaaac tccattatct tcacatttga tccagaggga
    51061 aaacgaacag aacaggacat ctctactgat ttgatgggga attttgttag tgtcgggatg
    51121 ttaaaaaaca aacttatcat agctcttcct aatacaggca cgacttctgc tttgttgaac
    51181 aataaccaat tagaacttcc ctacaccaat gaatctttaa aaaacttaac aggtaagcag
    51241 ctccgttctt ttttaagtga agcatctata ccactttgga taaaagtcct gacatttata
    51301 ttttctattt atcctagttt tctgaatctg ctgatcactt tgctatttac caacattgct
    51361 gcttttctct atgcacgctt tcgactaaca aaagctactt ttcttgattg tttaaaaaca
    51421 ttgatctatt caatttcatt gcctactata attgcaacaa tcttgatggt ctttcttcct
    51481 tcttttgaca ctagcgcctt cattgctttt gcaggaatct ttatttttgc tcaagctgtc
    51541 aaaggatggg caaaaatatc gatcaattaa gaaataaaga caactcgtta tttctacttc
    51601 aatagaccct tttagaggtt gtgacatttt tttgtcacag cccctttttt atttgaaaaa
    51661 tatttctttc tcaaaaaaca agcaaggcgc ttcaaagttc ttcttgtatg cgctacactt
    51721 agagtaaaga aaggcgggaa attaactatg tcagaaagaa tcatttatgc agatcgtcca
    51781 tttcgtgatg aatttatcga agaaatccat actatagcgc ctggttatat ctttaaaaca
    51841 gaattacaac cagaggatct acaaaatgta gagatcagtt tgggctggaa ctcagactac
    51901 caagaaaaac tattagcctc ttctaccttg aaatgggtcc aatctatctc agctggtgtt
    51961 gatcagctac cccttgagac tttttcaaag aaacatattt tactttcaaa tggtagtggc
    52021 atccacagtg aatcgattac ggagcatgtc ttaggaatca tccttgggta ttctcgtggt
    52081 ctttttcaag cacaaaaggc acagagtgac atgaaatggt taggttcatc ggtccattac
    52141 caatctatcc aagggaaaaa aatactaatc attggaactg gccatattgg aaaaatgatt
    52201 gcaaaaaaat gcaaagcatt agacatgaac tgctatggaa tcaatacatc cggtcatcca
    52261 gcagaaggaa tggaaaagac tttttcttta aatcaactaa aggaagttct tcctgaagta
    52321 gatttcgtag tcaatatctt acctctaacg gaggaaacaa ctgggctctt tgatcagcat
    52381 atgtttgaac actttgatcc aaaatctgta ttcatcaatg ttggccgtgg tgcttctgtt
    52441 aagacacaag atctggtgca ggctttaaat aaccagcaac tttcctttgc agcattagac
    52501 gtttttgagg aagagcctct tccacaagat catcctcttt ggaaaatgga caatgtactg
    52561 attacttccc acattgcagg tttgacacct gattttcaaa agaaattaat ggctattttt
    52621 ttaaccaatc tgaaaagcta ctttgccacc catgagcttc aaaccaatca agtaaaattg
    52681 tctgcaggat attaatagct gaaaacaata ttttcaaaag aaaaaagaga aggtgacaaa
    52741 aattgtgtca ccctctcttt ttttattgtt ttttaaagtg ataggttggc tcctccaggt
    52801 tgggattata atcaacaagt aaatcatatc ctttaaagaa ccattcatct gcttcctcga
    52861 taaaaaaaag tgtcccatca atttccactt tctttacagg atgttctggc tgttcaactg
    52921 acattccaat cgaaaaacca tcatgaacct ctgttttgcc gtagactttt ccaaaaaaac
    52981 gtattccgta agtttctggc agatcaattt ctgagtcaaa ccacttttgt gcttttggcg
    53041 ttaccgttaa tttcatccca acaacctact ttctcttttc tttctattga ttcatcttat
    53101 cgtctagaat atccacatcg cctgtctctc caataaccag tagattatca ttttcacgaa
    53161 catattcatc tgctgcagga gaagcgataa ccgtttgatc tactcttcgt atggcgacta
    53221 ctgttaagtc aaaacgttgc ctgaaattta attcagctaa tgttttgttg aaaaatttag
    53281 gattggagac tcggatttct gctaaagaat atttatctga caactctagg taatctaaaa
    53341 tattctttga cactaaatta tgcgcaatcc ttattcccat gtctcgctcg ggatggacga
    53401 cgcgatcagc tccgatcttt tcaagtactc tggcatgata ctcattttgg gcttttgcta
    53461 aaatatttgg tacgcccatt tcctttacca tcagagtaac taagatactg gcttgaatat
    53521 cttctccaat agcgacaatt acatgatcga aatttcttat gcctaatgat cgaagtgtca
    53581 tttcatcctg tgcatttgcc acaacagcat gagtggctat attcatatat tcattgaccc
    53641 gatcttcatt actatcaata gccagtactt cttgaccagc ttcgatcagt gttcggcaga
    53701 tacttccgcc aaatcgtcca agacctacaa ttgcaaaatt ttgtttcacc gttttcctcc
    53761 tttagtatct tcttttctca gtataacaaa gcctttacaa aaacaaaagc aagcatcatt
    53821 attgtaaaaa agccaagaaa aataatagtt attttctcag cttttgatta tcctctttat
    53881 catcgttttt atttcaccaa accatgtttg aatgcataga tagcggcttg tgtacggtct
    53941 tccacttcta gcttagccaa tatattggaa acatgtgttt ttactgtttt cagtgtaata
    54001 aacaattcgt ccgctatttc ctgattactt tttccttcag aaatcagcat taaaatttca
    54061 ttttcccgat tcgttagttc ttcatgtaat acaggctcat ttcgccgact cattttttcc
    54121 atcatttttg ttgtcacttc tggttctaat actcgctcgc cacgttgcgt tgcccttata
    54181 gcatcagcaa tttcatgtgc ggtagaggtc ttcaacaaat accctgctgc acctgcttca
    54241 atggcaggat aaactttttc gtcatcaata aaactggtta cgataatgat tttagcttct
    54301 ggccaatctt ttaagattgc ttttgttgat tcgataccat ccatttcttc catgactaag
    54361 tccattaaaa tgacgtccgg tcgaagtgtc atcgccttct catagccttg tcgtccattt
    54421 tcagcttctc caattacttc aatgtcttct tgaatagata aataaaaaga gacgcctaag
    54481 cgcaccattt catggtcatc tactaataaa acttttatca tccttatcta tgcctccttc
    54541 atcaaaggga ccttgatttc tacacttgta ccttgacctt taaaactaat gatttttact
    54601 gttccaccaa taccagctac tcgttctttg atattgttca atccataact tcccgttttc
    54661 gtttcattca tattaaaccc tgttccgtcg tcaataatac gtaacaaaag attattgtct
    54721 attttgtgca aatatacctc taattcattg gctttagcat gtcttaatgt atttgataac
    54781 aattcttgaa cgattcggaa caagtgatcc tcaatggaac tagatagttt tacatcttct
    54841 acatcccatt tcagcgaaat ctggatttta ttttgcaatt ccttcaataa ctgctcgata
    54901 ccttgcttta aacttttctc ttctaaattg actggacgta gatgaagaag cagcgcacgc
    54961 atctcagact gggaagcgtt gatgatctct gctaccattt tcaactgctt gcgaaacatt
    55021 tctggtgtct cgcttttttc tgcttgctcc gtcaatgccg acatcatcat cattgctgca
    55081 aacaattgtt gcgaaactga atcatgcagc tcacgggcta atcgatgtct ttctaattct
    55141 aaaatttctt ctttggtttg tccatctaca tattggggac ggctcgttac aatttgtaat
    55201 tcactagata cttcaatcat tttttctttt atcttagtga tttccttatc aatatctttg
    55261 atgtataaat cgtccgatgc acttgggatc ggaagaagca acaatttgga ttcataattg
    55321 ccagaagaaa gtgcacgcag cttttcttcg attttcccgt attttgtctt ttgaataagt
    55381 gataataata gaaagacaat taatcctaca cctaaggaaa tggctaacaa atggaagata
    55441 agcggaacat ataataaacg tgcacgcagt aattctcccc accaatgact ttgattgctg
    55501 gcataaaaat aagtgaaaag tgaaaataga ataataagga aagccgcaat ccccgaataa
    55561 acagctagca tcgctctgga tatttttccc atcatattcg tatcacctcg acatctccaa
    55621 tcaaggtatt agtaataatc ttcaatctac gagggttttc atcataatca ctgctgtaga
    55681 ttttgatttg ttcatttttc aaagaaaatt gctcttcttc aaacaagaca tttcctacta
    55741 atgtcgcatg ctctaatcgg atggctacgc ccaaaggtac taagatccgt gttctgccta
    55801 tcccttttct tacaatcaca atattatcat cttttggcaa aagcgtattg cccaaatcta
    55861 tgatagtatc accagaaatg acggcgatgt tgatatcgtc ccattcatag acgtcgtttc
    55921 caatacgttg gttaccgaat aattgctgtc ttttccgctc attattatgt gtttttaatt
    55981 gctctgtttg gatcatcatg atctgtttct ttcgccaaaa agcatttttg gttaaatcta
    56041 tccctgaaat ctctacacct ttcagaccaa taaataaaac ggcaaataca gccatcatcc
    56101 ataaagcagg actgttgact aagctaaaaa aaatgaccaa acttcctaat atcaattgaa
    56161 aattttgaaa tttagtacga ggatgtttgc gcatagctag atatatattg aaaataccga
    56221 atatcactaa aagcaaaagt ccagtattgt ttacgatttg ccaaacagca aataacagca
    56281 gtagtgcttc aactaccaca aaaaaacgcc aagaactatt catcgctctt tctccctcct
    56341 gacacattct catttcatca tacctatttt tttaactgtt ggctatagga ctttagatgt
    56401 aagatcgttt gttgaaatct aaaatacaca aagagaaaaa gatctagagt gtatcatcag
    56461 taagatgaac tctctagatc tttcagtcag actacgcttg ttctactttg acgattttaa
    56521 ctaacatatc gccacctgga gtagcaatag ttacttcatc atttttacgt ttgccaatca
    56581 atgcttgcgc aataggagaa tcattggaaa ttttgccaga aaacggatct gcttcagcgc
    56641 ttccgacaat cgtgtactct tcttcttctc catctggtag ttcgatgaat gtaactgttt
    56701 taccaattga tacctcatct gcatctacac cgtcgttatc gatgatttga gcaaaacgaa
    56761 tcatattttc aattgttgtg attcttcctt caacaaatgc ttgttcatct ttcgctgatt
    56821 catattcaga gttttcggaa agatctccga aaccgcgggc aattttgatt cgttcaatga
    56881 tttctccgcg tttgactgtt tttagttctt ctaattcttt ttctaatttt tctttacctt
    56941 ctagagtcat tggataaact ttctctacca tgtgtaacgt ctcctttttt cgataaaata
    57001 ccgcaaaagg taatcttttg aggaatatag tccaaaaaag attaccacgc ttttcttcaa
    57061 atgtaaatgt ttttctaaaa atgatcaatg tctagagcct gtttttctaa gaattattta
    57121 catatttttc cactaattcc atatgttctt cataagtttt agcgaaataa acatttccag
    57181 tgctcgtatc tgctacgaaa taataatagt cattttctgc tggttctaat actgccttga
    57241 ttgcctcttc gcttggattg tcaaaaggtc caggtccata gccggtattg gtatacaaat
    57301 tatatggtga atctacagct gtatcttcat acgtcactaa ttctttgtgt tcacctaatg
    57361 cgtataaaac agagatatct gactgaagtg gcatatttgc tttgattcgg ttaaagaaga
    57421 cttgtgcaat gtttttacga tcattttctt ttacgccttc tttttcaact agagaagcta
    57481 gagttaaaac ttcttgtaca gtcaaatttt tctgcttgat agctgaataa tagttttgca
    57541 tgaccgtatt cgtcttgttc accatttcaa tcactagatc cttaagcgaa gtactcgtgt
    57601 aataatcata tgtggctggg aataagtaac cttccaaacg gtattttgtg ttctcagctt
    57661 tagatgcact ttccaacagt tctgggaatt tttggtgcaa ctcgttaaag aaagtctcat
    57721 cattcactaa atctaaaaat tctttcttgt ctttaccagt taccttcgct acccgttcag
    57781 caatctgatc gatatcgtac ccttctggaa tggcaatttt cccatctgca acttttgttg
    57841 gctcagaagt accgccttct tgcaactgtt tgccaatctc gtcaagagtc atattaggcg
    57901 ctaactgata atagccagct tgaaagccag ttaaattttt aaattttgta taataattga
    57961 aaacaatccc gcttttaata atattgtcct tctccaaaat ctcaccaatc tgcttgttag
    58021 aagagccact cgggatctcg acttggacta attggtcatc tgatttatct aaaggcttca
    58081 acccgctatc tacataacga tacacggtaa atccaagaaa tccgccaata atcaataatg
    58141 taagagcaat cactaaaatg atcttcctca caatcttatc ttctttttta cgcagatttc
    58201 tccgcttgtc gattatatct gctgtagctg ccttactggc ttctttttta tctttacttg
    58261 ggtgttgttt gtttcctgac aaaacaactc ctccttacta tcaagttcgt aactttattc
    58321 attatacatg atatttgaat tggcgtgaat gattttattt aaatattcta tcaaaaatgt
    58381 aagtagtaaa tccattacta taagattaaa ataaatgtta tcaagataca agctatttta
    58441 gctttattct ttctgtaaaa aagaaaggag actaaataaa ctattatgaa aaaaggaaaa
    58501 catgctaaaa aaagaaaata ttcattttta atgatcgttg tcgtgttgtt tagccttagt
    58561 gcgttctcta caggaactat tcttggatgg caattttaca ataatgaaca ctctcagata
    58621 gttgcccatg ctcaatcagc tcaaaaaaag ttgatactga ctaccaatga acaacagctc
    58681 gttgaaaaaa tcgatcaact attaagaaaa aatgattata ttggctcaat ttacgtaaag
    58741 aaaaataatc gcatcatcat ggaaaaaggc tatggctatg cgaataaact cacgcaacaa
    58801 ccaaatgatc cttctcttta ttatcagatt ggttcggttc aaaaagcatt gactactctt
    58861 ttgattttaa aacaagtcga gcgtgggcac ctttctttag atactaagct ggctcaattc
    58921 tatccacaaa ttgctggcag ccagcaaatt actatccgtg acttgctgta tatgcgctca
    58981 ggcttgcacc gaactgcttc tccaaccata ccgatgactg atgaagaagt cgttcaattt
    59041 gcgattcagc acttaaaatt tacagattat cagacctctc attatgattc attgaacttt
    59101 accatattga ctggaatttt gatcaaatta acaaatcaac cgtatgaaaa attattgacc
    59161 gatgatatca tcgaaccttt aggattacag catacaaaat tttatgacca agtcaaaaat
    59221 tcatccaatc atgcactatc ctatcaaatg tctaaagagg atgattactt taaaccactg
    59281 acagaatctg aaacagagat ccataacgaa ttagggactg gtaatatcag tatgtccgtc
    59341 tatgatttaa atacgctgtt tacacaagtt ttatctggaa aactagtttc caaagactta
    59401 ctcttctcat tatggcgtga aaatgcgaat ggacatccat atagtggtgg ggtatatagc
    59461 ggagataatt atatcctgtc gcaaggaaat atcgactctt ttgatacatc tgctatattt
    59521 agcaaagatt cacaggatgc tatcatcatg gaaagcaata taaaagctga caaaactatc
    59581 aaactgccta ctgctgatct aagaaaccaa atctatgacc tgatggaagg aactactaag
    59641 ttggcaaata gctgatatga tgaaaagata gcaaatacta cttctttgaa tagcatttgc
    59701 ttaaaaaaag tactcgacta aacgtaggaa agagtgtggg acaaatctaa aaatcaattt
    59761 ttgctacaga ctttaattcc aaataaacag aacagaaaga ggtgttcttc tttctgttct
    59821 gtccaaatta ttctaagatt tctctttacc aacattattt gacaaagggc ctattaaatc
    59881 taaaatagta tctttagatt gctaaaatat gtgctagcaa atcattcatg gcttgttctt
    59941 atttttaatt ttatgcaata aaaaagaaga acaattagcg tgattataga aataaataat
    60001 gagattttag aaaaaa
//
LOCUS       DADVXK010000008        55423 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.008, whole genome shotgun sequence.
ACCESSION   DADVXK010000008 DADVXK010000000
VERSION     DADVXK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.008"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            137..994
                     /locus_tag="KB909_000467"
     CDS             137..994
                     /locus_tag="KB909_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBB6836528.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1109..2029
                     /gene="pstC"
                     /locus_tag="KB909_000468"
     CDS             1109..2029
                     /gene="pstC"
                     /locus_tag="KB909_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBB6836529.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2029..2913
                     /gene="pstA"
                     /locus_tag="KB909_000469"
     CDS             2029..2913
                     /gene="pstA"
                     /locus_tag="KB909_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBB6836530.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2928..3734
                     /gene="pstB"
                     /locus_tag="KB909_000470"
     CDS             2928..3734
                     /gene="pstB"
                     /locus_tag="KB909_000470"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6836531.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3750..4508
                     /locus_tag="KB909_000471"
     CDS             3750..4508
                     /locus_tag="KB909_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6836532.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4521..5198
                     /gene="phoU"
                     /locus_tag="KB909_000472"
     CDS             4521..5198
                     /gene="phoU"
                     /locus_tag="KB909_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBB6836533.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5436..5735
                     /locus_tag="KB909_000473"
     CDS             5436..5735
                     /locus_tag="KB909_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836534.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5761..6468
                     /locus_tag="KB909_000474"
     CDS             5761..6468
                     /locus_tag="KB909_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6836535.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6465..7232
                     /locus_tag="KB909_000475"
     CDS             6465..7232
                     /locus_tag="KB909_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6836536.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7332..8900
                     /gene="liaX"
                     /locus_tag="KB909_000476"
     CDS             7332..8900
                     /gene="liaX"
                     /locus_tag="KB909_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBB6836537.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9197..9517
                     /locus_tag="KB909_000477"
     CDS             9197..9517
                     /locus_tag="KB909_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBB6836538.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9517..9867
                     /locus_tag="KB909_000478"
     CDS             9517..9867
                     /locus_tag="KB909_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBB6836539.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10034..10972
                     /locus_tag="KB909_000479"
     CDS             10034..10972
                     /locus_tag="KB909_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBB6836540.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10987..11817
                     /locus_tag="KB909_000480"
     CDS             10987..11817
                     /locus_tag="KB909_000480"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBB6836541.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11861..12886
                     /locus_tag="KB909_000481"
     CDS             11861..12886
                     /locus_tag="KB909_000481"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6836542.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12901..13839
                     /gene="galU"
                     /locus_tag="KB909_000482"
     CDS             12901..13839
                     /gene="galU"
                     /locus_tag="KB909_000482"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6836543.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13964..14404
                     /locus_tag="KB909_000483"
     CDS             13964..14404
                     /locus_tag="KB909_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBB6836544.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14407..15009
                     /locus_tag="KB909_000484"
     CDS             14407..15009
                     /locus_tag="KB909_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6836545.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15077..16183)
                     /locus_tag="KB909_000485"
     CDS             complement(15077..16183)
                     /locus_tag="KB909_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6836546.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16393..17394
                     /gene="ccpA"
                     /locus_tag="KB909_000486"
     CDS             16393..17394
                     /gene="ccpA"
                     /locus_tag="KB909_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBB6836547.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17697..20042)
                     /locus_tag="KB909_000487"
     CDS             complement(17697..20042)
                     /locus_tag="KB909_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6836548.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20321..21223
                     /locus_tag="KB909_000488"
     CDS             20321..21223
                     /locus_tag="KB909_000488"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBB6836549.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21436..23211
                     /locus_tag="KB909_000489"
     CDS             21436..23211
                     /locus_tag="KB909_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBB6836550.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23468..24685
                     /locus_tag="KB909_000490"
     CDS             23468..24685
                     /locus_tag="KB909_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6836551.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(25132..26718)
                     /locus_tag="KB909_000491"
     CDS             complement(25132..26718)
                     /locus_tag="KB909_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBB6836552.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            26969..27193
                     /locus_tag="KB909_000492"
     CDS             26969..27193
                     /locus_tag="KB909_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBB6836553.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27335..29086
                     /locus_tag="KB909_000493"
     CDS             27335..29086
                     /locus_tag="KB909_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6836554.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            29086..30870
                     /locus_tag="KB909_000494"
     CDS             29086..30870
                     /locus_tag="KB909_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836555.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31328..32179
                     /locus_tag="KB909_000495"
     CDS             31328..32179
                     /locus_tag="KB909_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6836556.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32276..34162
                     /locus_tag="KB909_000496"
     CDS             32276..34162
                     /locus_tag="KB909_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6836557.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34203..35105)
                     /locus_tag="KB909_000497"
     CDS             complement(34203..35105)
                     /locus_tag="KB909_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6836558.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35335..36738
                     /locus_tag="KB909_000498"
     CDS             35335..36738
                     /locus_tag="KB909_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6836559.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36735..38171
                     /locus_tag="KB909_000499"
     CDS             36735..38171
                     /locus_tag="KB909_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6836560.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38316..39242
                     /gene="trxB"
                     /locus_tag="KB909_000500"
     CDS             38316..39242
                     /gene="trxB"
                     /locus_tag="KB909_000500"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBB6836561.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39455..41182
                     /locus_tag="KB909_000501"
     CDS             39455..41182
                     /locus_tag="KB909_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBB6836562.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41198..41548
                     /locus_tag="KB909_000502"
     CDS             41198..41548
                     /locus_tag="KB909_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6836563.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41632..42492)
                     /locus_tag="KB909_000503"
     CDS             complement(41632..42492)
                     /locus_tag="KB909_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBB6836564.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42584..43012
                     /locus_tag="KB909_000504"
     CDS             42584..43012
                     /locus_tag="KB909_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6836565.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43174..43350
                     /locus_tag="KB909_000505"
     CDS             43174..43350
                     /locus_tag="KB909_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBB6836566.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43377..43823
                     /locus_tag="KB909_000506"
     CDS             43377..43823
                     /locus_tag="KB909_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBB6836567.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43979..45358)
                     /gene="brnQ"
                     /locus_tag="KB909_000507"
     CDS             complement(43979..45358)
                     /gene="brnQ"
                     /locus_tag="KB909_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6836568.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            46064..47035
                     /locus_tag="KB909_000508"
     CDS             46064..47035
                     /locus_tag="KB909_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBB6836569.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            47059..49251
                     /locus_tag="KB909_000509"
     CDS             47059..49251
                     /locus_tag="KB909_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBB6836570.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49268..49744
                     /gene="ybeY"
                     /locus_tag="KB909_000510"
     CDS             49268..49744
                     /gene="ybeY"
                     /locus_tag="KB909_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBB6836571.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49728..50123
                     /locus_tag="KB909_000511"
     CDS             49728..50123
                     /locus_tag="KB909_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBB6836572.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50138..51037
                     /gene="era"
                     /locus_tag="KB909_000512"
     CDS             50138..51037
                     /gene="era"
                     /locus_tag="KB909_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBB6836573.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51180..51992
                     /gene="recO"
                     /locus_tag="KB909_000513"
     CDS             51180..51992
                     /gene="recO"
                     /locus_tag="KB909_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBB6836574.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52376..53293
                     /gene="glyQ"
                     /locus_tag="KB909_000514"
     CDS             52376..53293
                     /gene="glyQ"
                     /locus_tag="KB909_000514"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBB6836575.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53295..55370
                     /locus_tag="KB909_000515"
     CDS             53295..55370
                     /locus_tag="KB909_000515"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBB6836576.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        17958 a         9936 c        11787 g        15742 t
ORIGIN      
        1 agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta ttttgttatt
       61 taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca tactttagga
      121 ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag gattagccat
      181 tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg ctgttggctc
      241 ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag aaaatcctgg
      301 aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag tacagtcagg
      361 agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga tcgatgcctc
      421 agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga acaaggatat
      481 tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg agatcaaaaa
      541 ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg cttcaggaag
      601 cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg ttcaggcaca
      661 agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg gtgcaatcag
      721 ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta acggtgtaga
      781 accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg agcatatgta
      841 cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct tatctgatga
      901 agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata tgaaagtcga
      961 acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt acaaacttag
     1021 ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact gagtgagtat
     1081 gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat tattaacaaa
     1141 atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat gtatcgcgct
     1201 gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat tggccacctt
     1261 ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga atccaagcca
     1321 aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag gttcgtttat
     1381 tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag cagtattcat
     1441 gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg agctgcttgt
     1501 aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc cttttgtcag
     1561 aagtattttt ggcgggacag ggtttggtat cttagctggt acatttgtgt tgttcgttat
     1621 gatcttgccg actgtcacaa cgatgactgt tgatgcatta aaggcagtgc cacggcacta
     1681 tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca aagtcgtgct
     1741 acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc gtgcgtttgg
     1801 tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa caggacttac
     1861 tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata caatcatggg
     1921 aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga tgtcattatt
     1981 ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat gaacgcaaaa
     2041 cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat cgtattgatt
     2101 ttagcagctt tactacttta tatcttagtt cggggaatac cgcatatttc atggtccttc
     2161 ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca gctatttaac
     2221 tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt aggtgcgggt
     2281 atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg cacgtcgatt
     2341 gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt ggttttcgtt
     2401 attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac tgtattcaac
     2461 ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta cacacaacga
     2521 gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt ggtggttcca
     2581 gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat ttttggtgaa
     2641 gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt tacgaactgg
     2701 aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac attagctgtc
     2761 catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt ttcggctggc
     2821 gcttctgccg tgttgatcat tgctgtttta ctgttcaact tcggcgctcg tgcgattggc
     2881 aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg aaaaaatata
     2941 actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca ctatatacgg
     3001 atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat ctggaatttg
     3061 aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct acgtatcttc
     3121 gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg aaaatcatgt
     3181 atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc aaacggattg
     3241 gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat attacatttg
     3301 ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt gaaacaagct
     3361 tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt gccttggctt
     3421 tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg aaacctgata
     3481 tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga acggttgaag
     3541 aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat aacatgcaac
     3601 aagcagctcg tatcagcgac tatactgcct ttttctatct aggaaaagta atggaatatg
     3661 acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat tatgtgtccg
     3721 gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga aattatttca tctaaagatc
     3781 ttcatctgta ttatggaaag aaagaagcac taaaagggat caatctaagt ttcaatcaag
     3841 gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa atccacttat ctgcgttctt
     3901 tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt ttatataaag
     3961 acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa atcggcatgg
     4021 tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc tatggattga
     4081 aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa agcctgaagg
     4141 cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta tctttatccg
     4201 gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg gaaatcatct
     4261 tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc gaaagtatgc
     4321 tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg tctcaagctt
     4381 cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa tacaacgata
     4441 cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt tcaggtcgat
     4501 ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg ctgaatctcc
     4561 ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag tcagttcgtg
     4621 catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat ataaatatca
     4681 ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg caacagccag
     4741 ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat ttagaacgta
     4801 tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg cagacgagaa
     4861 taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa atggtggaca
     4921 acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc gccaatatgg
     4981 atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa aatatgcagg
     5041 aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt tatctagaac
     5101 ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct acagggaaaa
     5161 tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg attatgccgt
     5221 ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct gcatcaagta
     5281 ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg acttattacc
     5341 gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa aacatgtcac
     5401 aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt agcatcatca
     5461 ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagct gctttatatg
     5521 aagtacctgt catcgagatc gaaaaagtac gaataaaaga ggatcatcaa ttgattacag
     5581 gaagactgat gaacacggat caaaaaggag aatcgattta tttatcggtt ccttatcaaa
     5641 aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc caaatgcatg
     5701 gagatgaatg gcagctagta gcaaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5761 atctccattg gcgccatgtt gcttattggc ggaaaacagg gtctatttgc tttaggaagt
     5821 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5881 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5941 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     6001 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     6061 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     6121 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6181 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6241 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6301 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6361 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6421 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6481 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6541 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6601 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6661 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6721 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcgatc caaggtttta
     6781 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6841 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gctagtgtag
     6901 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6961 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     7021 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     7081 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     7141 ccacattgtc tgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7201 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7261 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7321 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7381 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7441 taaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7501 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7561 gagaaaggca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7621 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7681 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7741 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7801 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7861 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7921 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7981 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     8041 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     8101 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     8161 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8221 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8281 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8341 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8401 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8461 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8521 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8581 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8641 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8701 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8761 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8821 gtgtttcaga tggtgaaatc acgcaagtgc aactttcaac gacaacagga agtatctatt
     8881 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8941 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta
     9001 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     9061 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     9121 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9181 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt
     9241 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9301 gctttatgta ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt
     9361 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9421 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9481 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9541 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9601 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9661 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9721 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9781 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9841 gtcagtgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9901 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     9961 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
    10021 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
    10081 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
    10141 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
    10201 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
    10261 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccggc
    10321 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
    10381 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
    10441 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
    10501 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggtc atcgattgat
    10561 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
    10621 taaaatcctg gaacatctaa ttgaaatccg aggaatcggg atcattgatg taatgaatct
    10681 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
    10741 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
    10801 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
    10861 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
    10921 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
    10981 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
    11041 tggtatgcat tgatcatcgt atcaggtatc attatcgcca tgtggcttag cagcagagag
    11101 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
    11161 atctccatta ttggtgctcg cttatattat gttttatttg atcttcccca gtatatagct
    11221 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
    11281 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
    11341 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
    11401 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
    11461 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
    11521 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
    11581 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
    11641 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
    11701 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
    11761 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
    11821 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
    11881 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
    11941 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
    12001 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
    12061 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
    12121 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
    12181 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
    12241 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcgaa
    12301 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
    12361 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
    12421 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
    12481 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
    12541 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggag taggcgatct
    12601 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
    12661 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
    12721 tactcaagca gcgatggaac tagcccaaat aatggaaatc gaaatgccca tcactcaaac
    12781 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
    12841 acgtgatggg aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
    12901 atgaaagtca aaaaagcagt tattccagcg gcaggattag gaacaagatt tttaccagca
    12961 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
    13021 gttgaagaag cgttgaaatc aggaatcgaa gacatcttga tcgttacagg aaaagctaaa
    13081 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
    13141 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
    13201 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
    13261 aatgaaccgt ttgtcgttat gctaggcgat gatatcatgg aagatgaagt accattgaca
    13321 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
    13381 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
    13441 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
    13501 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
    13561 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
    13621 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
    13681 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
    13741 tatatcctgt ctttaggtaa aaaattagaa gcagaaggaa gcaagatcga tcataatcca
    13801 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
    13861 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
    13921 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
    13981 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
    14041 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
    14101 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttgctggt
    14161 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
    14221 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
    14281 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
    14341 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14401 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg aacagccgca
    14461 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
    14521 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
    14581 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
    14641 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
    14701 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
    14761 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
    14821 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
    14881 gaaggaatgt cagaagcaaa accagttgca gatgacacaa aagaaatgat gaaaatggca
    14941 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
    15001 aatcactaaa atcactaaaa tcacaaattt atagaataaa aaggtgggag cggactagct
    15061 ctcacctttt ttactcttat ttttctaaaa ctagtaattc ttttggtgta gtcgtgaatg
    15121 gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct actttttcag
    15181 gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact aagtcatttc
    15241 cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct aaacggtgat
    15301 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    15361 ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca agagtgatgt
    15421 tgtatatttt ttcttggaag tcggttggtt tttgataagc aattgtacga gtagcatcac
    15481 tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc ggtgaaatct
    15541 tcgtgtttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    15601 cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcgatttct gcaatgatcg
    15661 cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca acatcggccc
    15721 atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt tgtagacgtt
    15781 ggatgatgga agctagatca gtgtaagaat ccgttcccgt caagatatca gagatagcat
    15841 cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc tgaccatagc
    15901 gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa tagccacgga
    15961 catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga gtgaaaagga
    16021 aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga tcactttcgt
    16081 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg acttggtgtt
    16141 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    16201 aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa cgttctaaaa
    16261 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tcttgagatt
    16321 atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    16381 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    16441 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgtcaa accagcaaca
    16501 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc agttgcgcgt
    16561 ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca tccctgatgt cagcaatatg
    16621 ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa atacaatatt
    16681 atcttagcaa attcagatgg taacgaccaa aaagaagtca atgtattgaa taacttactg
    16741 gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga aatccgtgga
    16801 gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc agatgaacaa
    16861 gtaggtagcg taaacattga ttatgtatca gcaacaaaag atgcagtaaa caaattggca
    16921 aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc tatcaatgga
    16981 caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc atatagcgaa
    17041 ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt cgatcggatc
    17101 cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat cggtattttg
    17161 gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat cacaagtaac
    17221 aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca accattatac
    17281 gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    17341 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa ataataaaag
    17401 gacaaccatt cagaggttgt gagcctgccg tttaactctg cgttacaagg agcaatttca
    17461 aaaaacagca tttcatgttt gatgaatatt gtgactcgtg attcggagtt ggcaggagaa
    17521 caccgtttat tcgggaaaag gggttatgac aaaattttgt ttaatccttt ttttttgtct
    17581 taaaaaagag agaaagtggt tgaaattaca tttatcgtat ataaaacaat ccgtgtatag
    17641 atgctgcatt atgttcacca ccatcaaaaa aataagggac tgtgtattct attaaatcaa
    17701 tcatctttct catctgattc tttggttgct tgattcgctc ttgcataagc tgaagcggtg
    17761 ttccagtaat ctgtatagtt ttcatcggta ccgccaacgc caaatttaaa ggcgcttttc
    17821 ttcggtccat ttttcgccca tagcgattca actgtttttc ctggtgtttg gatggatttt
    17881 ttattgacag taacttttcc aggtgtttga ccagtaaatc cagatacttt tttcttcatc
    17941 acatcagatg ataattcgaa tttctcatca gtgccaaaaa tgtcaggttt tgcttggtaa
    18001 gcttgattga tcagattggc aagataatta gccgaacgta tccttgcttt gctgtccatt
    18061 ccagtattgt catcgtgccc tgcccagcta ctgatggtaa tagacggagt agagacaatt
    18121 agccatgaat ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcttttcct
    18181 agatttccgt ttaagcttga gatggcatct ttgaatggtg tagtgatttt tgcattgatc
    18241 acactgcgca tcatgtcatt catgatcgat gccgttgctt ccgaatagat ccggacagag
    18301 ttgctttcgt gtttataaat tacatttcct gcgttatctg tgatggaatc gatgatatag
    18361 ccttcttcat agacgccgcc gtttgctaaa gcctgaaatc cattggtctg ttgaagcgtc
    18421 gtgacatcta ctgtacctaa aggagcagat tcaacgcccc aattgtcatt tgccgggtag
    18481 ttcatctttg ccaagtagtg ctcgtaagca tattgtttcg atccaccgga attcaacaca
    18541 tcttgatata agtgataagc cgggatattg ttggaccatt ctagtgactc acggacggtt
    18601 tggaaggtgt tcgatccttc gttagtagca ttgacgattt tctcgccagc attttctcct
    18661 tcttgccaag ttgttgcata atctgataca cgggattctg atccgataag ccccatgtcg
    18721 attgcaggtc cataaacaag aactggtttg attgatgagc cagcttgacg ttctgtatcg
    18781 aaggcatggt tattttgatt ctgactgtaa ttccgtccgc caacgaatcc gtagatgcgg
    18841 ccagttctgt tatccatcaa tacatttccg gtttctactt gactgccagc accatcatct
    18901 aacatgtatc cataattttc tacgccattt tgcaatgcag catagacatc tttatcgatt
    18961 gtcgaatgga ttgtatatcc tttattttgg atcgtttgct gtgccttttg ataataagcg
    19021 tcactgaccg atgaatcaga catatcagcg ttgtcttttt cagccaattg ttgtgcaatg
    19081 attcttgttg cttcattcat cacagtataa tacaagaatt ctctgtcagt ctgttctgcg
    19141 atttgttgtg gtagaaagtc ttttgtaagg tcataggctt ttgcttcttc gtattgttct
    19201 ttcgtaattt ggccttcacg atacatactg aataaaacaa aatcttttct ggcaaggccg
    19261 gcagaaagat cttcttttag cgcacctgtg ttcgtgtatg gactatacgt gatcgggctt
    19321 tggggtaatc cagcgatata agcagcttgc ggcagcgtca catcttttgc atctacacca
    19381 aagattcctc ttgcagcttc ctggactcca gcaatgtttt gtcccttatt attacgacca
    19441 aatggtgaga cattcaaata cgtagcaatg atctcatctt ttgaaaagta tttttctact
    19501 tgtgcagaaa gaatgatctc gtttgcttta cgtttgaatg ttgtttcatc tgtaaggatc
    19561 tgctgtttga ctaattgctg tgtcaaagtt gatccaccag aagagccaat accagtagct
    19621 tcagatacta atgctcgtaa aacagcttta ggaacgtaac cttggtgttt atcgaagtat
    19681 tcatcctctg tgctgataat tgcagttttc aataaaggtg aaattttatc agatgaaata
    19741 gtcgtgcgca tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc
    19801 tttgacgttt ctgtaatgtt tcctagttct gtctgcagtg cttttttagt cggcaattgt
    19861 gtgtcttcga cgagataggc aaaatagcca gcgcctattc caatacctag agctgcgaac
    19921 atcaaaagaa gaacagtaat aaaaacagtc aatgattgaa aaactctaaa aataatctta
    19981 ggaacaaacc atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc
    20041 aaaagggtca cctcaactaa tggttttatt tcgctaatta tagcaaataa tagaacaaaa
    20101 aaacagacaa ggctgttttt ggcaggaatt tcttttttaa aagagttaaa acgtgagaaa
    20161 atgatctttt ttataaaaga gttcttaagc ttttctttag agaaaatttc agttactatg
    20221 gagaacaggg caaagaaaaa tcaatcattt tctttgtata tcatcttacc aatatatagg
    20281 aattgttagt aacaattgcc tttcaaggag gaatccatcc atgttattag gctcacacgt
    20341 cagcatgagc ggaaagaaaa tgctgttagg agcagcagaa gaagcagcca gttatggatc
    20401 ttcgactttt atgatctata caggcgcccc tcaaaacact agaagaaaag ccatcgaaga
    20461 gatgaatatt gatgccggaa aagcgtacat ggcagaaaac ggtctaacaa atatcgtcgt
    20521 tcatgcccct tatatcatta atttggggaa tacgatcaaa ccagaaatgt ttccttttgc
    20581 cgtccaattt ctgagagaag agattgttcg tgcggaagct ttaggcgcta ctcaaattac
    20641 acttcaccca ggtgctcatg taggggcagg aacagaagcc ggaattgcta gaattattga
    20701 aggcttgaat gaagttttga caaaagaaca gacggcacaa atcgctttgg agacaatggc
    20761 aggtaaaggt acggaaatcg gtcgaacatt tgaggaatta gcgcaaatca tcgatggagt
    20821 aaaattgaat gaaaaattat ccgttacttt tgacacctgt catacgaatg atgccggtta
    20881 taatattaaa gaagactttt caggtgtaat ggaagagttt gataagatca tcgggttaga
    20941 tcggcttaaa gtactccata tcaatgattc taaaaatccg caaggttcgc ataaagaccg
    21001 gcacgccaat attggttttg gaacaatcgg attcgacacg ctgaataaga tcgtccatga
    21061 tccaatgttt gacaatattt cgaaaatctt ggaaactccc tatgtcggca aagataaaaa
    21121 gaaagcttac gcaccatatg gaaaagaaat cgccatgttc aaagcacaaa tattcgatcc
    21181 agaagtgttt cctgagttat tagcagaaga agtgatactc taagattttc tatctgacag
    21241 cagcaaaaaa ggaccaggca cattgccttg tccttttttg tttaagaaac aaaggagtgc
    21301 tttttgcagt ctttttcatc atgcatcttc tcccccctct ttttaaattt agacaaacag
    21361 ggtatactgg tagaaaagta aaaaaacgaa aagtttcaca agcaagtggc aaaacgtgat
    21421 tggaaggacg aaaagatgct gaacacttta aaacccttga tcaaccaact aaaaaagaaa
    21481 catacatact ttattcttgg catagcccta ttatttacaa ttattcgttt gtatttatat
    21541 agtaaagcaa tctatggaac agacatgtcg gcaacctatg atgaccagct gctgattcgc
    21601 tatgctcaaa atattttgga cggtaaatgg ctaggggagt atacgactac aacactttcc
    21661 aaaggaatct cctacagctt atttttagta cttgcacata aactgcatct ttcttatgca
    21721 gttttgttcg gcatgttcag tatttttgcc agtatattgg ttgcactcgc gtttaaaccg
    21781 atcgtgaaga acaagtatct tcttttaagt ttctattttt attttttgtt ttctccgatt
    21841 agttttacac atgaatattc cactcgaacg tatcgtaatg ccctcgtgat tccggctgtt
    21901 gagatcatta tcgcttgttt actagctatt tattaccgta aatatagttc cagcaaaaaa
    21961 atgctgccgt ggtttttagg gctagctgtt tcttttcctt tcttttggtt cattcgcgaa
    22021 gattccatct ggcttcttcc ttttactgta gtcgcgttag gcatcagttt cgtccagatc
    22081 ttgctaggac aagacttttc tttcaaagaa gcaaagaagt taaaagaacg accatttctc
    22141 ctttcgaaac aagaatggct gaaactttca ttgtttttac tccctctagt cggtttctcc
    22201 atcgtctatc agtggatcga atataaaaac gagacaacat atagtattgc cgccatcaat
    22261 gaccgttcga gtggcgaatt tggacgtttg atgaaacagc tgatccgaat agatgacgaa
    22321 acgaacttaa ataaagaaaa cagtgagata tgggtctcgc atgctgcatt aaataaagca
    22381 ttagacgcat ctcctacatt tcatgctgtt tctactcgta ttgacgaatt gtatacgact
    22441 catgcgtgga cccaaggtgg aaaagtaaaa gaattaccag gagatatcat tttttgggca
    22501 ttgcgagatg tggtaagcga atctggttat taccaaaaca atgcaaaaga aaccaatgat
    22561 ttttggaaaa aagtcaatca agaattagaa gaagcctatc aaaagggaac tatcaaaaag
    22621 aaaaaagaat tctatctgat gggatcaggg gatggaaaga cgatgaatga tctgccaatc
    22681 gtatttgctt ttctgaaatc aggatatgcc tatgcatggc gatacaaaga tttccatcaa
    22741 ggggggaatt atagtttcgg tacgcaagaa caagtcgaac aggcccaaga attattgaat
    22801 cttccactaa tggataattg gatcgatagc agtgatccga gaacacctga tttccagttg
    22861 acaaaaacag caaaagtcgc gaatgtcatg ataaaaattt accaagttct ggccattccc
    22921 gtgctgattg cttcaatagc agggatatta cttatgatac taggaaccgc atttgcaaaa
    22981 gctgatcgtg cctattatag ttcctctttg attgtagtca ccggattaat actgacacaa
    23041 ttggtttttc ttttcggcgt ctcgtggttt tgttcttatg cgccagaaaa aaaggattat
    23101 tttttaagtg tctacactgg cgcaggcgtg ccattaacgc aattcatcgt agtaacaagc
    23161 atgctagttt tcagtaaatt gaatctgaaa aaagctttat cttccaaata aaaacatact
    23221 aagattagag gagaacatca ttgacgaatg atgttctcct ctattttcta tttttagatt
    23281 atagtgaaga gtgaaagaaa gttcgaacaa agccttgagg actatgagtc cctatcaaaa
    23341 accgaacttc tttactgtca ttttagaatc aggtttacgt atgttggggc catgagcccg
    23401 tgtataggaa attggaatcg aaatgaagca gtaaagttct ttcaaaactt aaaaaggagg
    23461 aaaacaaatg ccttacattc ttgcattaga tgtttcaatg ggacacagct acagtgtcct
    23521 atacaaagac gacacctgct tatttgaaga cgagatcgaa cacactcaaa gaggatttca
    23581 tgcattactc gaagagatcc agcacttgcc tgaacgtcca ttgattgttt ttgaagcaac
    23641 ggggatttat tccagaccag tcgaaaagtt ctttcaagat catcactttt cttactgttt
    23701 gttaaacccg ttagaagcga aaaaacagat ggaagaaaac accttatgca gttggaaaac
    23761 agataaatcg gatgcccatc ggctcgcaca gactcatctt aaaaatcaac gtcagccaaa
    23821 agaagtacaa agcaattttt acttagagat gcgcgattta gcccgttttt atcaagaaat
    23881 tgagaagaaa atcactcgtc tgcgcatgga tttacacaac tgccttcagt tgacttttcc
    23941 agagcttgaa cagttctttt taaacaggct gaccccttac gcattgatat tgatccgtct
    24001 ttttccccat ccagattttg tattggcatc tactcggaca aaaataaaaa ataaactgat
    24061 caacgaaaca cggaaaaaaa tctccgcgaa tcgtgccgag caaaaggcag atcaaatcat
    24121 ccactatgca cagtgtgcct atccagctgt tgaaaaagac agtatccact gtcaaaaaac
    24181 gatctattac gctgaacttc tccaagattt actcgaacaa aaagaagcac tggcgacaca
    24241 aatgatcaaa aaagccgaag gctctccttg ctttttgttg taccaaacgt tccctgggat
    24301 tggcgcactc acagccgctt tattgctcgg tgaattagga gatatcacac gatttaaaac
    24361 ccataaacaa ttgaatgcct ttgtcggaat cgacatccga cggtatcatt caggtaagta
    24421 tactggccaa gaccgcatca ataagcgtgg taatcccaaa gcacggaaaa ttattttctt
    24481 caccattcga aatatgattc gccagcaacg cgcagctcct aatcatattg tcgattatta
    24541 ctacaaatta aaaaagcaac ctatccctaa gaaagataag gttgccacag ttgcttgtat
    24601 gaacaagctt ctgaaatgta tgcacgctat ggttagggca catacagagt acgactatgc
    24661 gtacgcggtc tcagtggacc attaactaaa ccacttacag tataccactt ctttgcccag
    24721 atcgaaaatt ttttacgaac ggggctttat ttggtgtgcc ttgattttgt cgctttcgtt
    24781 tatgagctat ttttcttaca ccttttactt gactaatcgt aggaaaggga actgtgacaa
    24841 aagtcttgtc gcagttcctt tttccgaata aacggtgctc aaaagcttgc atctgcggta
    24901 ataagtccaa ccaagttaaa aacataaaaa gctgttttta cttggctgtt cttattactt
    24961 gatgcaaggc agctttttca caacctctga tacacggtgt tccagaagta acttcttcgg
    25021 aaataagccg aaatttcaca aaaatttgaa aagcaatttt cttaaattcc ttcttatttc
    25081 ttgaagctgc ccacttctga cacaacctcc tttgtgtaaa agaatcagtt tctactcgat
    25141 ttcttctatc gtttcctgca aacgctgttc atattttttg tttcctttat ataaatcacc
    25201 aatcgtccat gccaacagga gaaggacaag aacaatgatt acataagcga tttgatcagc
    25261 caatgctagt tgagctgagg tggcttgctc gccgaagaaa ctttcgattt gacctggtaa
    25321 tcctcgtaaa ttcaagtaag tcagactaat cacagagaac cagccaagta gttttacaac
    25381 aaatgaattt ttgaatcggc tccccatctc cgcttggcta ttggtcatca tcagtaaagg
    25441 aatcatcgag aatggcaatg caaaagccag aaaaacttgg gattcattca tcaagttatt
    25501 caaagcggta tgttcttcga tcgttccttt tgtacttgta aacaaaacac aaatcaatac
    25561 aggaatcaca gaaagcaatc gtgtgactag tcttcttagc caaattggga tacgcatatg
    25621 gatgaagcct tccatgatga cttgaccggt caacgtacca gtaatagtag agttctggcc
    25681 agaagcaaga agtgctacag caaataaagt agacaagata ccagattttg ctacagcaat
    25741 caagatacca ttgctcatag ctgatggatc agataaagct tcatacagac caaaaaagga
    25801 aggatcttgg acagaaccgg ttttgaatac agccacaccc atgatcaata gcagtgcatt
    25861 gactagaaaa gccattgaca actggatatt agaatcccaa gtagaaaagc gtaccgcttg
    25921 tgctacatct tcttcgtctt ggtgatcgat cttccgagtt tgagaaactg ctgaatgaag
    25981 atataagtta tgcggcatga ctgttgcacc aataatccct aaagctccag tcagcggagt
    26041 ttcgccgccg atgaccggtg agtctgagaa tgtgtgactg ttagggataa atccggcaaa
    26101 caaactgtgc caatcagggt tagacaagcc aacttgatag acgaaaacga ataaaatgac
    26161 gaaaatcaag cagacaacca aagcttcgat tttacgaaac ccgacttttg tcagcaataa
    26221 aaggacgaaa acatctaaca cagtgataaa tacggcaatt accaatggaa tatcaaaaag
    26281 caggtagagg gcgattgctg caccaatgac ttctgcgatg tctgttgcca taatggctaa
    26341 ttcagtcaag atccataaaa tgacacccaa tgtcttactt gtccgtgctc ggattgcttg
    26401 ggccaaatcc atttgggtca cgattcctaa ttttgctgcc atatattgta aaagcatagc
    26461 aatcagacta gacatcaaaa taactgacat caataaatat tggaaatttt gtccaccagt
    26521 gatcgaagtg gaccagttac ctggatccat ataaccaact gctactaatg cacctggtcc
    26581 agagtaagca agaagtgttt taaaaaaact ttttcccttg ggtacatcca ctgttccatt
    26641 tacttcagct aaagataaac catttgtatg ttcaataagt cgatgcttat gaaattgttt
    26701 gttggattga ttattcaaga aaaaaccacc tttcctattt atctacgatt acattctaca
    26761 cctcagaaag aaaaaattaa agaaaaagat ttggtatgcc taattttttt tcgtggcgtg
    26821 tcttgctggt taatgaaaga aattttgttc ttctctaaaa aaaccactat tttttgcatg
    26881 aaactaaaga atacgccttt cttttttcaa taaactttag taaaataaat cattgagagc
    26941 aattcggaaa tagaaaggag agatttatat ggtatcaaca ggtattgtcg tacttattgc
    27001 tattattgct ttgctaatcg gcgcagtagg tggctttttc ctagcgcgta aatatatgaa
    27061 agactattta gaaaaaaatc ctcccgttaa tgaggacatg ttgcgatcaa tgatgatgtc
    27121 aatggggcaa aaaccatctg agaagaaaat tcgccagatg atgcagcaaa tgaagaacca
    27181 agggaaaaaa taggttctga cccaaagact ttttgcgggc tgattttttc agtccgtttt
    27241 ttatttcgta atttgttaga ctattcagac tattcagcaa aaaagacaag cacagacaat
    27301 cctatgctct tgataaagac aaaggaggag taaaatgtcg atttttagaa aattaggttg
    27361 gttttttcga caggaaaaga aacattattt aattgggatt ttctccctat tcgcagtggc
    27421 cttggtacag ttagctcctc caaaagtgat tgggatcatc attgatgaga tcgccgataa
    27481 aaatttatca ataaagatca tttcctggtg gatcttatta ttgatccttg cagctctctt
    27541 acaatatctt tttcgttata tctggcggac gaatatttgg ggaagtgcag ctcggttgga
    27601 gaaagaactt cggcagcagc tattcaaaca ttttacagaa atggacaatc tcttttacca
    27661 aaaatatcgg actggagatt tgatggctca tgcaacgaat gatttgaatg caatccaaaa
    27721 tgtagcagga gctggtatct tgacctttgc agattcagtg atcacgggcg gaacaacgat
    27781 cattgcgatg attttgttta ttgattggcg cttaacactg attgcgctga ttcctctgcc
    27841 tttactagcc gttacttcac gagtgctggg gtcaaaactc cacgatgctt ttcgtgattc
    27901 gcaagaagct ttttctagta tcaatgataa gacacaagaa agtattactg ggatcaaagt
    27961 cattaaaaca tttggacaag aaaaagaaga tctcgcggat tttgaagaaa agattgaaga
    28021 tgcaattatt aaaaacaaac gagtcaattt tttagactcc ttatttgatc cattcattac
    28081 cttgattatc ggtctgtctt atgttgcaac aattatttta ggtggaaagt atgtcttgga
    28141 aggcacgatc tcaatcgggc agatggtctc atttattagc tatatcggta tgcttgtttg
    28201 gccgatgttt gcgattggtc gattgttcaa cgtattggaa agaggaaatg cttcttatga
    28261 tcgcgtcaat gaacttttgc atgaaaagac gcatatcgtg gaacaactgg gtgcagtgca
    28321 gactccggca aaaggcgagc tgaatgtagc tatttcctct tttaactatc cgaaagaaga
    28381 atcaccagca ttagaacaaa tcaaatttgc gatccaagaa ggagaaacat taggtattgt
    28441 tgggaaaact ggtgcgggaa aaacgacaat catcaaatta ctgatgcgtg aatacgatga
    28501 ttatcaagga aaaattcaat ttggcggatg ttcgatcaaa gaatattcat tgaatgcttt
    28561 attaggatca atcggctatg tgcctcaaga tcacttcttg ttttcgatga ccattcgaga
    28621 taatatccgt ttttctaatc caaaactttc agaagaagaa gtagagcatg cggcttcttt
    28681 agcatttatc aacaatgaaa tcaaggaatt accaaaaggt tatgatacct tagttggaga
    28741 acgtggagtc tctttatctg gcggacagaa acaaaggatt tcgattgctc gagcattgat
    28801 caaaaatcct gaattgctga tcttagatga tgcactttct gcagtagatg ccaaaacaga
    28861 agaagctatc ttgcataatt taaaagaaat aagaaaagag aaaacaacca tcattgcagc
    28921 tcaccgttta agcagcgtga tgcatgcaaa agaaatcatt gttgtcgatc aagggaaaat
    28981 cattgaacga ggaacccatc atgagctgct tgcattaggc ggctggtatg aacgaatgtg
    29041 ggagaaacag aaattagaag cgaagataga aggaggcgag gcctgatgga tgaaaattat
    29101 caatcggaat ggacaaaatc gattccactt aaagaacaga agaagatcat caaacgactg
    29161 atgaagttcg ccaaaccttt tagaagaacg ttcatcgttg ctatcttatt tgcgtttgcc
    29221 ctgtctgtga tcaatgtcct attgccaagg atcatccaaa cttttatgga tgatcatctg
    29281 gctaaacagt cggctacgac acaagttatt ttgttttttg ctggtatgta cttgtttgga
    29341 gtcatagtca aaagtatcat ttggtttttc caatggtatt tgtattccat ggcttcattg
    29401 aagacctatc agtatgttcg ggtaagatta tttgaaaagc tgcatacact aggtatgcgt
    29461 tattttgatc agacaccggc aggatcgact gtttctcgag tgacaaatga cacagaaacg
    29521 ctatttgaat tttggtatgt ctttttgatg gtattgactg ggatctttgc agtcgtttct
    29581 tccttcattg ccatgtttca aatcaatgga gaaattgcct tgtggacttt ggtgttcttg
    29641 ccgattttag gaatcgtcat ctggtattac cagaaattca gttctcgtat ttaccggaat
    29701 atgcgggaaa aattaagtca gctgaacacg aaattgaatg aatcgatttc cggcatgcgt
    29761 attatccagc agtttcgcca agaagctcgt ttagctaaag aatttgaaca agtgaacaac
    29821 gagtatttag acacgcgcta tgcgatgatc aaaacaaatt cgattctgtt aagtccgatc
    29881 atcaattttc tatatgcatt ggcgattgcg ttggcgttga ctttgtttgg gatcgatgcg
    29941 ctgcattctc ccgtagaagt tggactgatc tatgcattta cgacctatgt ccagggattt
    30001 tttaatccaa tgtctcaaat gatggacttt ttgagcacct ttacagatgg aatggttgcc
    30061 ggtagtcgta ttttgaaaat catggataca gaagaatatg caccgcaaca aaatcctgga
    30121 gcagatcaag cgattacttc aggtaagatc gagtttcgca atgtaagctt ttcttatgat
    30181 ggagagcaca atgtattgaa caatatctct tttgtcgcta atccgggaga gaccgttgca
    30241 ttagtggggc acaccggaag cggaaaaagc tcgatcatca acgtattgat gcggttttac
    30301 gaattttatg aaggccagat cttgattgat gatcatgaca ttcgagaata tccaatggaa
    30361 gagttacgta agaaaatggg attggtcttg caagatgcct tcttgtttta tggagatatc
    30421 gcaggaaata tccggatgat gaatccaact atcacagacg aacagattcg ccatgcagct
    30481 gagtttgttc aagcaaacaa gttcatcgat gaattaccaa aaggatatca ctcaaaagtg
    30541 atcgaacacg gtgccagcta ttctagcgga caacgacagc tgatcacttt tgcgcgaaca
    30601 atcgtgacag atcctaaaat actagtattg gatgaagcga cagcaaatat cgatactgaa
    30661 acagaaggat tgatccaaga aggattgaca aaaatgcgac aaggacggac aacgattgcg
    30721 attgcccatc ggctgtccac gattcgggat gcagaattga ttttagtttt agacaaaggt
    30781 catatagtag aacgtgggaa tcatgaaaca cttctagcgc aaaatggttt gtatgcagat
    30841 atgtacaaac tgcaaagcag tggtgtgtaa aaagtggttg tgacagggct ccgttcagct
    30901 ttaggtgata agaaaaaaat tgtaaaaaag gctttccaga tttttgcata aatttggctt
    30961 atcaccgata agctggtact ggaacaccgt atattagaag ttgggacagt agcatagtag
    31021 cattttgacc taagcgctag agtgaaaata aaacagagct tcccagattc ttcatctgtg
    31081 agcgttagtg tcgtaattac cagatttaaa aaaaatcacg acagctagtc agaagtgccc
    31141 aatagccgct aagaaagcgt tgacaaaagt gcttgctttc gataatataa agaaaacgat
    31201 acaacttgga tagtgattgc ctgatgcaag ctaaacctga tgagtctccc atggttccat
    31261 ggacggcttt ttgggttttt ctttttgttt tggatacagc cctatatatc atggaaagga
    31321 gtaaaacatg ctgattgaga aagtactgaa taacaacgtc gtaataacca gggatgaaag
    31381 aaatcaggaa atgatcgtga tgggaaaagg tttggcattc aaaaagaaag tgggtgaccc
    31441 gatttttgac tcatgcatcg acaaaaaatt tcagttgaca aatgacggac tttcacaaca
    31501 gttccaagaa ttggcacaag cgattcctct tgagtactta gaaatttctt gtgaaatcat
    31561 tgaatataca aaagaggctc tacaagtcca gttgaatgat tcggtgtata ttgcattgac
    31621 ggatcatttg tatacggcta tcgaacgtca caaaatggga atatttgtac caaatgtatt
    31681 gctgtatgat atcaaacaac tatttcctaa agagtatgcc atcgggaaaa aaacagtgaa
    31741 gaaaatctcg gataaatacc acatcaagtt atcagaagat gaagccggat ttatcgcatt
    31801 gcatttagtc aatgcacaag gcattcaaag ccaacaagac aatacctacc tgtttactac
    31861 aacaatacag gatattctaa atatcgtccg ctattactat aagattacat ttgatgaaga
    31921 ttcagtccat ttttttcgat tcgtcacaca cctacgtttt tttctgacac gcgtcctaga
    31981 tggagaaaaa tcagaagtgg gagaagtttc tgaggaattg taccaggtta ttcaaaaaaa
    32041 atataaggat acgtttggtt gcgttgagaa aatagcagac tttttagccg agatattcaa
    32101 ctaccagatg tccacggacg aaaaaatgta tttaacgatc catattgcgc gtttagtgca
    32161 tgagaatcgt tgtaaataaa taaaaaaagg aggataaatt aacaagaacg catgaaataa
    32221 gggtagtgac attcagttgg ctaaaccttc cactaataaa ttggagggaa tagaaatggg
    32281 aaaatatcaa gaattagcga gcaaaattgt agaaaatgtc ggcgggaagg aaaatatcaa
    32341 tggtttgaca cattgtatca caaggcttcg tttcaaatta aaaaacgaag aaaaagcaaa
    32401 tgatgagatc ttgaaaaata tggacggtgt tgtgacggta atgcgagcgg gaggacagta
    32461 ccaagttgtc atcgggaatc atgtgccagt cgtgtttgaa gaggttataa aagcaggaaa
    32521 ccttactttt gatgaggctg tttcaacaga aaaaatgaga ccgtttgata tgcttattga
    32581 tggaatatcg ggctgtttcc agccattcct tgctattcta gctgctggtg ggatgattcg
    32641 tggactgaca gcattacttg tcttcttagg cgcatttgac cgcggttctg gcacatttgt
    32701 tatgtttgat aatatcggtg attctgtatt ccaatttatg cctgttatta tcggtttaac
    32761 agctgcccgt aaatttaaag taaatgaatt cgtagggatg ttgcttgggg cagcattaat
    32821 gaatcctagc ttgtcgctgg aagctttgag tggtgcagca gaagcaccac tgactaccat
    32881 attttctggc actatttttg aagcacctat ttatcaaaca gtattcggca ttccctggat
    32941 tgcgcgtaac tacgcttctt ctgtcattcc cattatcttt attgtgttgt tagctagcca
    33001 aattcagaaa ccaattaaaa agttagtacc tgagatgatc gcgaatttct tcgttccatt
    33061 cttcaccgtt cttattacaa tgcccttagg ttttttactc gttggaccag cattcacatt
    33121 cgcaactgat attttaatgg ctggatttga aacactttta gcactttcgc cagttattta
    33181 tggagcaatc gtaggcttct tctggcaaat tctagtgatg tttggtctcc attgggcaat
    33241 cgtaccaatg ggattgatgc aattttctgt gaatggttgg caaaatatca tgacacctgt
    33301 tgcagtagtg tcttttggac aaactgcagc acttactgca ctctacttta agcttagaaa
    33361 cccaaaagac aaagcaatcg caataccagc cattgtttct ggtattgtgg ggattacaga
    33421 gccagctatt tatgggttta cattgccacg taaaaaaata tttattttta cctgtgtcgg
    33481 tggtgcgtta gggggcgcgt atagtggatt aatgaattta acttcttgga atccaggtgg
    33541 attaggcatc tttacaattc ccaactatat tagaccagat ggtgatttaa cggatgtgat
    33601 taatgtattg attggaatcg ccattgcgat ggtggtatcc tttgcgctga cttttttctt
    33661 ttggaaggag gaagcaggtg aaacagatga tagacagaaa agatcaggta aagaaattgt
    33721 aaaaacaccg atacaaggac aaatcgctcc actgaatgca gcaaaggatg cagcttttgc
    33781 acaaggaaca ctaggtcgag gaatcttgat ctaccctgaa aaaggagaag tacgtgcccc
    33841 ttttgacgga acagtcatga ccctgttccc gacgaaacat gcaatcggaa tggtttctga
    33901 agcaggtctg gaattgctga ttcatgtcgg attggatact gttcagttgg aagggaaata
    33961 ttttgaaagc ttggtgcagc aaggagaaag agtgaaacaa ggcgatctgt tgctccgctt
    34021 cgacaaaaag aaaatcgaag aggaaggata cagtttagaa acacctgtga tcgtcaccaa
    34081 ttacacggat tatttggata ttttggaaaa tcaaggggag acggtcgggc cagacgatgc
    34141 acttatcacc gcactgacct gaacggttag gtgaaagaat ggactaggct taattattct
    34201 ttttagtcca cttctttatt ttcaaaattg aaaggctctt tcatgatggc tgagctgata
    34261 gggcgtttat caaatttttg tcctacagaa attagatgga ctaaattctg ttgataattt
    34321 tctgcaaaaa cacaactata taacacgtct agaagataac aaatcgatgt attgatcgta
    34381 aaattaccaa ttttcgaata cagtcgttcg cgtgtcgtaa gtcgcaaagc ggctgtactc
    34441 attgaagata gcgttgaatc accgatactg gtcaaagcta aaattggaac atgattttgt
    34501 ttcaatattt ctgcggtacg aaggatcaca ttgttttcac ccgtataaga aatcagaatc
    34561 ccgcacatat cactcgtgca attgtacgct tcatagaacg attcaccaaa agtggtgaca
    34621 atcgtgacat ccattttgat gcgcttcatt ttcagcatga aatcttgaga aatcaaagta
    34681 ttcgagttac tggcgaaaat cacgattttt tttgcttgaa gcattagttg tttggctttt
    34741 tgcagttggt catgatgaat gagagaaagt gtatcttgaa tcgtcatctg ttctaaagaa
    34801 gccattttat ttgcgatcgt cataataccg tctgtggtgg aaaaaggaag attcgcatct
    34861 acgtcttgaa aattcccttc aagataggct gtttcagcta aaaaagcatt acgaaaactg
    34921 acccagccat caaaacccat tttttttgct acacggatga gtgtggacgg gtggacataa
    34981 catcgctcag caatctcttg gatggtcatt tcgccaagtg ctggagaatc gcttaagaga
    35041 aactgaatca cttcattttc tgaaggagaa aaggagattt ctttgatttt ttcacgtaat
    35101 aacatgtaga taccttcttc ttgttttttt acgtaaatta taactttttt gaaaatgatt
    35161 tgtaaacgga tttatgttat atagcttaat aaagacattt tttgacaaga tatttacaaa
    35221 aatccagtag aaaacactaa cttttgtaaa tgttactgga aagaaacgaa tttctattgt
    35281 ttgttttgtt tacaaaaaag ataataaaag tgtaaaaagt aaaggagtga gaacatggca
    35341 aaaggaatca aaatcgctac gattggtgga ggcagcagtt acacccccga gttgatggaa
    35401 ggatttatca aaagatatga ggaattaccg atacgagaaa tctggctcgt agatgtagaa
    35461 gaaggaaaag aaaagcttga gatcgtcagt cagatgtctc agcgtatgtg ggatgcttct
    35521 ccgtatgaag tcaaaatcta tgcaactctg gatcgggaag aagcattgaa agatgcggat
    35581 tttgttacga ctcagtttcg tgtcggtcaa ttagatgcac gaatcaaaga cgagcggatc
    35641 cctagttatt atgggatgat tgggcaagaa acaaatggtg ctggcgggat attcaaagct
    35701 tttcgtaccg ttccagtggt tttggcaatc gttgaagaca tgaagcgttt atgtccaaat
    35761 gcttggctga tcaatttcgc gaacccaagc gggatggtga cagaagcagt tatcagatat
    35821 ggcaaatggg ataaagtgat aggattatgc aatgtgccag taatggcgat gatgacagaa
    35881 ccaacaatgc ttggcaagaa aaaagaagag ctgatctaca agtttgccgg tctaaatcac
    35941 ttccattggc acaaagtagc agataataaa ggaaatgacc gcacggcaga attgattgat
    36001 cgtttatacg atgaagacaa tggattgccg aaaaatatct ttgatatccc gtttttcaaa
    36061 gaacaattaa aacaaatgaa catgatccct tgtggctacc accgctatta ctaccgtgaa
    36121 gaagaaatgc tggaacatgc tttagaagaa tatcaaacga ttggtacaag agcgcagcaa
    36181 gtgaaagaaa cagaagcaga gctgtttgaa ttatacaaag atccagaatt ggatcataaa
    36241 cctgaacaat tgcaaaaacg aggtggtgct tattattcag atgctgcctg tgaaacgatt
    36301 gcttcgatct atggaaataa agaaacacag atcgtggtat ctacaaagaa tgatggagct
    36361 gttcctgatc tgccggcaga ttgtgtagta gaagtcactg cctatgttgg cgcacaaggc
    36421 gcacgaaatg tagcgtttgg ttcccttcct gctgctgaaa gaggctggtt gcaagtaatg
    36481 aagaatatgg aattgctgac gatcgaagca gctgtgactg gtgattatgg aacagcttta
    36541 caagcgttta cgatcaatcc gcttatacga tcaggaaaga cagcaaaacg gatcatgaat
    36601 gagttgttta ttgcacatca gcagtattta ccgcaattca aggaaacaat cagccggtta
    36661 aaagcagaag gaatcgaagt ccaagatgaa ctggcaagag aattatcaag caatacacat
    36721 gtaatggagg aagtatgatg ggattcagaa aagatttttt atggggcgga gctacagcag
    36781 ccaatcaatg cgagggcggt tatgatgaag gcggacgtgg gttagcgaac gtagatgttg
    36841 tgccaatcgg agaagaccgt tttcctgtca ttactggaaa aaagaaaatg tttgaatttg
    36901 atgaaaatca tttttatcca gcaaaaattg cgatcgatat gtatcatcat tataaggaag
    36961 atattgcttt atttgcagaa atggggttca agacttatcg gatgtccatt gcttggagtc
    37021 gtatttttcc aatgggcgat gaaaaagagc caaatgaatc tggtttgaaa ttttatgagg
    37081 atgtctttaa agaatgtcaa aagtacggga tcgagccgct tgtgacgatt acacattttg
    37141 attgtccgat gcatttgatc aaagaatatg gtgcgtggcg ttccagagaa ctcgttggtt
    37201 tttatgaaaa tctgtgccga gtcatcttca atcgctataa aggacttgtc aaatattggt
    37261 tgacattcaa tgagatcaat atgatccttc atgcaccatt catgggcgca gggctgtatt
    37321 ttgaagaagg agaaaatgaa gaacaaatca aatatcaagc ggcacatcat gagttggttg
    37381 caagtgccat cgcaacgaag attgctcatg aagtagatcc ggagaacaaa gtaggctgta
    37441 tgctggcagc aggagcatat tatccataca cttgcaatcc tgaagatgtt tgggcttcta
    37501 gaaaatcaga tcgagaaaat tatttcttca ttgatgtcca gtcacgagga gaatatcctg
    37561 cttatgcatt gaaagaaatg gaacgaaatg gcattcagat caaaatggaa cctggggatg
    37621 ccgcattgct gaaagaacat actgttgatt ttatctcctt ttcttattat tcttctcgag
    37681 tttcgactac tgacaacgaa ctcttggaac agactgcagg aaatatcttt gcttctgtca
    37741 aaaatccata tctggaagca agtgaatggg gttggcaaat tgatccatta ggcttgagaa
    37801 taacgatgaa tgatatttat gatcgttatc aaaaaccact atttattgta gaaaacggct
    37861 taggtgcagt cgatacgccc gatgagaatg gttatgtgga agatgactat cgaatcgact
    37921 atctggcagc acatatccag gcaatgaaag atgcagtaga attagatgga gtcgatctat
    37981 taggctatac gacttgggga tgtattgatt tagtatcagc tggtacaggt gagatgaaga
    38041 aaaggtacgg attcatttat gtcgatcgtg acaacgaagg aaatggcaca ttagcccgtt
    38101 cgaagaagaa atcattcaac tggtataaaa aagtaattga ttcaaatgga gaaaatcttt
    38161 cgaatgattg atcaatgatt tataaaagtc tattgttttt cagcggattt ttcgagtata
    38221 ataaagctat tcgagaaacg caagcagaac aatagacttt ttttcgcatt ggctgtaaag
    38281 tatgcttact tgattaagta aaggagaatc tacatatgta tgatgtaatc gttattggcg
    38341 caggtcctgc tgggatgact gctgctttat atgcttcacg ttcaaactta tccgtattga
    38401 tgatcgaaca aggcgcccct ggcggccaaa tgaacaatac ggcagaaatc gaaaactatc
    38461 ctggtttcga ttcaataatg ggtcctgatc tagcttataa gatgtatgaa ggtgtttcaa
    38521 gatttgggac agaaaatgct tatggaatcg tgcaagatat caaggatcac ggcagccaca
    38581 aagaagttat ttgtgaagat aaaacttacg aaggaaaaac agtcattatc gcaacaggct
    38641 gtatccaccg taaattaggc gtacctggcg aggaagaatt tgctggacgt ggcgtttctt
    38701 actgtgcagt ttgtgatggt gcgtttttcc gtaacaaacg tctagtagtg atcggaggag
    38761 gagactcagc agtagaagaa gccatctatt tgacacaatt tgcttctgaa gtagtcatcg
    38821 tccaccgtag agatgaatta cgtgcacaaa agatcatcca agaccgtgca tttgcgaatg
    38881 aaaaaatttc ctttatgtgg gatacagtcg ttgacgaaat cgttgggaat gaaatggtag
    38941 tgacaggtgt gaaagcacgt aatgtcaaaa ccggcaatga gtttgatttg gcagcagacg
    39001 gagtattcat ctatgttgga ctggatccat taactgcacc atttagagaa gcagggttga
    39061 cgaacgaagc tggctggatt ccaacagaca acgaaatgaa gacgaatata ccaggcgttt
    39121 ttgccatcgg agatgttcgt gaaaaagatt tgcgacaaat cactactgct gttggtgatg
    39181 gtgggatcgc tggacaacaa gtgtataaat acttggaatc tttagaagaa acaactgcat
    39241 aagtttaaaa agagtggaag aacggtttaa ttgttctttt actctttttt ttcgcgtgaa
    39301 atctactgaa tccgatttat gcgaatactt gcaaccgtgc ttgataaaag aatcctttct
    39361 tgatttaagc gttttttggt cctcatactt tcatatctaa taagtgaatg ctatacttat
    39421 taagaaccat atttcagaaa gaggtgttat tttcatgtct tgggaacaag tgtatgaaca
    39481 atgggtacat gaagaaaatt tagaagaaaa cttaaaaaaa caattaaatg atctgggtga
    39541 agatcctgaa aaacttgaag atgcttttta tgcaccgttg gaattcggta ctgcaggcat
    39601 gcggggaatc ttagggcctg ggatcaatcg aatgaacatc tatacggtaa gacaagcaac
    39661 agaaggactt gcacgtttca tggatacaca aggcgaagaa acaaaacgcc gaggtgtcgc
    39721 tatcgcttat gactcacgcc atcaatcacc agaatttgcc atggaagcag ccaaaacatt
    39781 agcacatcac aatatcccat cttatgtatt cgaaagtcta cgtccaacac cagagctttc
    39841 ttttgcagtc cgtcatttga agacgtttgc gggaatcatg gtaaccgcat cccacaatcc
    39901 agcagcttac aacggatata aagtctacgg agaagatggg ggacaaatgc ctcctgcaga
    39961 cgcagatgca ttgacgaaat atgtccgtga agtcagcaat ccgttaaaag ttgaagtatt
    40021 atctgacgaa gaagctgaac atagcggatt gatcacgatc atcggagaag aagtggatgc
    40081 cgcttatcta gaagaaatca aagcagtaac gattgatcat gaattggtgg aaacaatggg
    40141 gaaagatttg aaacttgtgt acacaccact tcacggaaca ggaaaaatgt tgggcgaacg
    40201 tgcgttgaaa caagctggat tcgaacaatt cgtactagtt ccagaacaag ctgtcgcaga
    40261 cccagatttc actacagtca aatcaccaaa tccagaagaa cactctgctt ttgagtatgc
    40321 gatacgactt ggcgagaaag aaggcgctga tttgctgatt gcaacagatc ctgatgcaga
    40381 ccgtttaggt gcagccgttc gtttgccaaa tggctcctat gaagtattga ccggaaacca
    40441 aatcggagca ctgtttgctc aatatatttt ggaagcacac caatcgcgag gcactttacc
    40501 tgaaaacgca gcggtattga aatcgatcgt ttctagcgaa ttacctacag caattgcgga
    40561 acactatggg gctaccatgt tcaatgtatt gacaggattc aaattcattg ctgaaaaaat
    40621 tcaacaattt gaagaagatc attcccatac ttttatgttc ggattcgaag aaagttacgg
    40681 ttatttagtt aaacctttcg ttcgcgacaa agacgcgatc caagcattgc tcttattagc
    40741 agaagtagca gcttactata aaaaacaagg caaaacgttg tatgatggct tgcaaacgat
    40801 ttttgaaacc tatggctact acgcagaaaa aacgatttct gtgacaatga gcggacaaga
    40861 aggttctgcg aaaatctctg ctttgatgga aaaattccgt gaagaagcac caacagaatt
    40921 tgccggagca aaagtcatcc aaacagaaga cttcaaagag ttgacgagaa cagaccgtga
    40981 aggaaacgta gaaaaactaa cgacaccgcc atctgacgta ttgaagtata cgctggaaga
    41041 aaatggctgg atcgctatcc gtccttcagg aactgagccg aaaatcaaat tttatatcgg
    41101 tgtaaaagga aactcttcag aagacgcagc tgaaaaagta gccgcttatg aaacgattat
    41161 ccaaaagatg acagaagaat aaaaaaactt gagactgatg gaaaaagtgg taaactttag
    41221 aagtcagtct tttttcaagt tggaggtgaa tggattgcca gacacgcaaa aaacaaaagt
    41281 agagaaagtc agccaactat tcaaaatgtt gagtgacccc actcgtctca aaattctgct
    41341 gtatctgaaa gacggggaac aaaatgtgac agcaatcatc caagcagtgg aaatggaaca
    41401 atctgctgta tcgcatcaac tgcgtttatt aagagaaaac catgtcgtca agtcccatcg
    41461 tgagggaaaa gcgattttgt atagtcttga tgattctcac gtactggata ttttgaacca
    41521 gacactcaaa catgtggaac atcaataacg ataggtgcaa atagagacaa actggactgt
    41581 gtcaacgaat cttcttcgct gacacagtcc agttttttta aagaaaaatt gttagtctgt
    41641 ttcttcggtg gtttcagttc cataataact atggtcttct aggtctaaag cattcaaaat
    41701 aagcgaagct gtttcttcaa tagataaaga agcgacattg attactacgc agcccaattt
    41761 ttcataaaga tcattcgcaa aatcgagttc agctcgtatt ttttcgatat cggaataagc
    41821 agtatcagga tttaatccgt aagagcgcat ccgttcttta cggatattgt ttaaaatatc
    41881 tgggttattc gtcagtccca cgattttttt aggatcgatc tcccaaagct gtttgggaat
    41941 atgtgcttgt gggatcaaag gtagattggc aacttttaaa tttttgttag ctaaaaacaa
    42001 gctcaaaggc gttttggaag ttcgggatac gcctagcaaa acgacatctg cttctagaaa
    42061 cccacgagga tctttcccgt catcgtattt tacagcaaat tccattgctt tgatccgttt
    42121 gaaatagttc tcattcaata aatgaagggc gccaggttgc cgaatgggct tgataccagt
    42181 taagcgctcg atttctgata tcggcggagt catcacatca aaactaaata attgatgttc
    42241 ttcacaaaaa gaacgcgtca tctcgatcaa ttcttgattg atcaatgtgt gcaggacaag
    42301 agctttttct tctagtgcat cttgcagtgc ctgcatcaat gttttctcat ctgtcacaaa
    42361 tgttctgcgg aataaattga actcaacgct aggatattgg gccatagtgg cttgcgctag
    42421 ttttgtcgca gtttctccag cagagtcgga gatgacaaaa aaagtaacga tttctgtaga
    42481 atcggaagac atggataaaa cctcacttgc atttttttta tgtttattat accatactct
    42541 agaatgtgta cttcgtaatc attttgattt ggaggaataa gtcatgaaaa aacagacgtt
    42601 gatcgaacaa tcactagaaa cattgaaaaa taacggtttt aaatatacta aaaaaagaga
    42661 agcattgtta acttatttag tgaagcgcaa tcgctacgta tccgctaaag aagtttttga
    42721 ctatatgaat caggaattca aaggagtaag ttacgatacg atttatcgaa atctccatga
    42781 ttttgcagaa atcgatttac tggaagaaac cgatttaaat ggagagatga agtttcgttt
    42841 tcattgctgt caaggggaaa tcggccatca ccatcacttt atctgtacgg tgtgcggaac
    42901 aacgaaagaa atccatatgt gtccaatgaa ttatttcgaa gaacagctcg gtggatgtac
    42961 gatcgaaggg catagattcg agattttcgg aagatgtgaa aattgtcaat aaggatttaa
    43021 ataaaataac atttgataat tttaaaaaaa agcaagattt ccttgacggt caaaacagca
    43081 ttagatataa tatttacagg acagtcttgt tttttgagat atatttcaat aacaattacg
    43141 gttacttttt aagctcggag ggagggaatt aacatgtcaa aaacagtcgt tcgcaaaaac
    43201 gaatcacttg acgatgctct tcgtcgcttc aaacgttccg tgtcaaaagc gggtacttta
    43261 caagaatctc gtaaacgtga attctacgaa aaaccaagtg taagacgcaa gaaaaaatct
    43321 gaagcagcta gaaaacgcaa aaaattctag ttctgtgatg aattggagtt ggtagtgtgt
    43381 cactactaag tagattaaac gatgacatga aaacagcgat gaaagcgaaa gataaggaat
    43441 ctttacaagt catccgaatg atcaagtcat ctatacaaaa cgagcagatt aaagaaggtc
    43501 acgacttgac agaagaagaa gaattaacgg tgttgtctcg cgaaatgaaa cagcgacgtg
    43561 attctttgca tgagtttgaa gaagcaggac gtgacgattt agctgaaaaa gtaaaaagtg
    43621 aaattgtgat agtcgaaaaa tacatgccgg aacaactttc cgacgaagaa attcgacaac
    43681 ttgttcaaga agcaatcacg caaactggtg cttcatcaat gaaagaattt ggcaaagtca
    43741 tgggtgcgat catgcctaaa gtcaaaggaa aagcagatgg aaaccaagta aatgccattg
    43801 tgaaagaact attacaatct taattttatc atttaaactg cggacaatca ttgtccgcag
    43861 tttttttgtg ctcgtaaaaa agagatctaa aaaatagcta gacgaaagaa taggattctt
    43921 tcatctagct gtttttttcc tgtttaatat ttcttatgtt aaattgtgtt tgatctggtt
    43981 attcttctgg tagttcattt gcttcttgtt tataccctga taggcgatag gcgtaataga
    44041 agagtaagct gccagcatac ccaagtaacg ttgggaccat ccagccaagt cccaatgcag
    44101 caaaaggaac gtgatgatga taaaattcga gcatgcttgc tacaactctt tgttgactca
    44161 ctaaagcagg cgaatttgcc agcatatcca atacggcggg aacagcagca aacaacatcg
    44221 ttacttgata gacaaatggt gtcttttgga aaaattttgc tgttaaggaa agcaaaatca
    44281 acgcaagcga caatggatac aaaagcatca atactggtaa agaccattgg atgatattgt
    44341 ccaaaccagc atttgcaacg acaaaagaga cgaaagtcgt taaccgcagc catgtcatat
    44401 aactgacttt agggaacagt ttatggaaat cttgtgcaaa agaaacaacg agtcccatag
    44461 cggtagtgaa gacacctaat gtgaccatca ctcctaagaa gctagcgccg aagttaccta
    44521 aataaaaatt agtgatctga gaaagtgcag ttccgccatt ttctgataaa gacatcttat
    44581 tcaaactcat cgcaccgaga agaacaagac caaaatagat catgacttct agcgcaacgc
    44641 tcaggctacc agcttttgct gttaattctg tgactttttt atctttgaaa ccaaggtcac
    44701 ggactgcatg gacaaaagtg acacttaagg caagcaaggc tactgcatca accgtgttat
    44761 aaccttctag gacaccattt gttaaagcgt ttgtttggta agtatctgca gcagattgat
    44821 ttagatttcc cattgggtgg aataaagaaa cgacaaaaat gattgctaat aatgcaagaa
    44881 acaaggagtt tagatacttt ccgacgtatt tgaccaaccg tgtgggatgg acagtaagga
    44941 aataagcaag taaaaagaaa agagcagaga ataaaaacat acctaatgaa ttatattttt
    45001 caggcaaaaa tggtttagca gccatttcaa aagcagtagc agctgtccgt ggtgtaccga
    45061 aaaatggtcc gatcgtcaaa tgaacaagga ttaagaacaa ggcagcatac cattttccga
    45121 caggtttagc taagtcatac agaccatcac tttttgtcac tactacagct aagatagcta
    45181 gtaatgggaa aagagcgcct gagatggcaa atcctacgcc agcactgacc cagtttgcgc
    45241 cagccatttg acctaagtgg acaggaaaga ttagattacc tgacccgaaa aacatcccga
    45301 agataagtga actgaccatc aatagttgtt tccatgaata agtttttgtt tcttccataa
    45361 atttttcctc caataattat cattttgatt gacgatataa acgttgcagc aattagtaat
    45421 gccactaata tcagattcca tgaaaaccac caccttaaaa tataaaaaaa agcccttttc
    45481 cacttgggaa aagggctcta gattctagaa cggtaccacc ttttttcgct taaaaaagct
    45541 tcttcattca cggacgcttt ttgataaagt tatccgctag cctgataatg gaggcagcca
    45601 caatgatcta cgttttcgac attgactcgg aaatgatgtt cgtctattcg atttattgtc
    45661 atttctcact tacatgactc actgggaata aatcgttgaa tagcctactg ttttcctcga
    45721 cgctttgctg tatgtttatt tgttgacgta ataatacacc tgtttttttt gaaatgcaag
    45781 aatattttaa ctattttgtt ttcttttttt gaaacaagaa aaatacctag agaatacctc
    45841 tgaatgaaac ggaatatttt gttctccact ttcatataac ttacattctc agattctttt
    45901 tatcaaaacg agacctttag cgaatggaaa cagctatttt ttaacgtttc ttggtacgta
    45961 tggttaaacg actcttttac aaccttttct tatttgctat atagtttctt ctgagtatgg
    46021 taaaatagga aagaatgaat cgaaaaaaag gggatgtcta tttttgacgg aagagtctag
    46081 ttctttagag attagattga cagctgctga tgatgtcagc atgcttttag gtgcacacga
    46141 caagcatata aaactgatcg aggaaacaac ggaaacaacc atccatacac gtggagaaat
    46201 cattcagatc attggtgaac aatcccagat ttccttggct gcctcagtca ttcggacatt
    46261 acaggaattg atcaaacgag gaatccacgt aagtacacca gatgtcgtga cggcattgaa
    46321 aatggggcaa aaaggtacat tagattattt tgttgagatg tatgaggaag agatcgtcaa
    46381 agaccgtaat ggaaaaccta tacgggtaaa aaacagcggt caaaagaaat acgttgaatc
    46441 ggtagccaaa catgacatcg tatttggtgt agggccagcc ggaacaggga aaacgtttct
    46501 tgccgtagta ttagcaattg ctgccctaaa aaaaggcgaa gtgcaaaaaa tcattttgac
    46561 gcggcccgct gtagaggcag gggaaaacct aggctttcta cccggggatc tgaaagaaaa
    46621 agtggatcct tatctgcggc ctgtttatga tgctttatac caaatttttg gattggatca
    46681 tacgaaccga ttgatggaac gaggcgtaat cgaaatcgca ccattagctt acatgcgggg
    46741 gcggacattg gatgatgcat tcgttatctt ggacgaagca caaaacacga cagtcgctca
    46801 gatgaaaatg ttcttgaccc gtctcggtta tcaatcaaaa atgattgtca atggggatac
    46861 aagtcagata gacttgcctc gagggacgac aagtggtctt gttcatgcag aacgaacact
    46921 aaagcaaatc aaaaaaatcg attttgttaa ttttgaagca agtgacgttg ttcggcaccc
    46981 tgtagttgcc gaaatcatca aagcttatga aaaggcggat cttcatcaag aataagcttt
    47041 gcttaggagg ataagcacat gttgaataaa acactgcaga aactacaaga aaaactcgga
    47101 aaggcagcat tgcctttcct tctgttcttg ttttttatca ttgtctgcgg cgttacattt
    47161 agtagtgtca aacaaaaggc caatgatttc agagaaggcc aagtagcaga agagagtatc
    47221 cgtgcgaata aaacgatcga gaacacggaa gaaaccgaac aaagaagaaa actggcagca
    47281 gaagcagtga ctccagaata tacttatcaa aaagatctgg cagatgacca gaacaatcgg
    47341 atcaagcaat tattcgaatt gatcgataag acgaatgata ccatcaacaa atcttataat
    47401 gacaaggtag ataaggcgaa ggaagatgaa aatatcccga aacctactac agaagagcgg
    47461 attgctacac tgaagaaaaa ttttgaaaac gtgaatgcag aaaacgttgc gttttaccaa
    47521 aaactgccga acaattttta ttcgacgata tttgaaatga ctgaaacgga aattcacacg
    47581 gttagggatg aaagtttgaa gctcattgac gaacagatga gtaaacaagt tcgtgaaagc
    47641 gaattggaag cttttaaaca agaagcagaa gatcagattc agtatttgaa tgtcacaaca
    47701 gagcagcaac aaatgattcg ctacttagtg gatcaaggca ttgtagtcaa tgatgtattg
    47761 aatgagaaaa agacagaaga attaaaacaa tctgcacgag aagctgtaca accagtgatg
    47821 atcttccaag gagaaatcat tgttcgcgaa ggaaatcaaa ttgatgcttc agcgatgaaa
    47881 aaattggaat tactaggatt gacgaatcaa acgacttcga ttttcccact cattgccatg
    47941 gttttagctg ttttgcttca aatcggcgta ctgatttata attcacttca attccaaaat
    48001 gcaggagaaa gaacaaaata cgtgcttttc tatgtgacag ctatgtcagt cagcatagtg
    48061 ctgatgaaat ttttccaatt attccaaacg gaacaagcta cttatatccc gctgttttat
    48121 cccgctgctt ttgcaccact tgttttaagc tttttcttga accgaagagc agggatcatg
    48181 gctggtattt tccaagcagt atctgcactt ttcatttttt atgattcgat tggcacgaac
    48241 tttctaacga ttatcttgat gtcttatgtt ttctctgggc tcatggcaac gattgtcaga
    48301 cgcaaacgga tctcagaaca aggattatct gctgccatgt gggtcattat ttttcctgtg
    48361 atgatggatg tcattttgat cgtctatcaa ggaatgagct ttggtgatgc aacgacttgg
    48421 ttaatgcttg tctgcgggtt cactggtgca ctcttctcat tcttgctgac gatcggtcta
    48481 cacccatata ttgaattgat ggtcaatgat gacagtgtaa ttgtattaaa tgaactcagc
    48541 aatccaaatc atcctttatt gaaacagttg ctggaagaag cgccaggtac ttatcatcat
    48601 agtatgatgg tagctaatct aagtgctaac gctgtagcag aaatcggcgg acgttctttg
    48661 ctaactcgag tagcttgcta ttatcatgat atcggcaaga tcaaacatgc tagctttttc
    48721 gttgagaact tgccttcagg agcggaaaac ccgcacaatt tcttattgcc agaagacagt
    48781 aaacatatta tctttggaca tgtgacagat ggagccaaaa tattggaaga ttataatatg
    48841 ccgcaaatgg tgatcgatat ttgcaaacag catcatggaa ccacgctaat gcgttatttc
    48901 tacatcaaag cgaaagaacg caatccggaa gtaacagaag agcaattccg ttatcctgga
    48961 ccaaaaccgc aaagtcgtga agcagggatc gtcaatattg ctgacagttg tgaggctgca
    49021 gtacgggcaa tggatcatcc gacgagcgaa aaaatcgaaa gttttgtcca taatcttatc
    49081 gaagagcgta tttccgatgg tcaattagac gatagtggac tgaccttgaa agaaatccga
    49141 aaagtggaaa aatcattgat cagcggttta agtagcacct tccattctcg gatcaaatat
    49201 cctaaaatga aaacagaagt tgagaagata aaggaagaac aagaagaata gaaagaagcg
    49261 atgtataatg gatattacct ttatggatga aacaaaccaa gtctcagaag agaaaatgaa
    49321 agaaatcgat gacttgctgc aatttgcagc atcttattta aagctgccag aggaaacaga
    49381 aatgtctgtt actttcatgg acaatgcggc aatccaagta atcaatcgtg attaccgtgg
    49441 aaaagatgca ccgacagacg tcatcagttt tgctctggaa gaagaaggcg aagacgaaat
    49501 cccagtgatt tttgaagatg gagagaatcc tttgcctcgt gtactaggag acatcatgat
    49561 ttctattgaa cgtgctgctg aacaagcaga agcttacggc cattcatatg atcgggaact
    49621 tggcttttta gcggtacatg gattcttgca tatcaacggg tatgaccata tgacaccaga
    49681 agatgagaaa gaaatgtttg gtttacagaa agagatcttg gatgcctatg gactcaaaag
    49741 ataaaaacgt agagaaaaac aaacatttcc tgatgtctgt ggaatttgct gtccaaggag
    49801 tcaaaaccgt ttttgaggaa gaacgcaata tgaggaaaca tgttgcgttc ggtatccttg
    49861 ctttatttat gggcgtgatt ttccagcttg atcggataga gtggttatgg ctgcttttag
    49921 ctgtttttct cgtttggata gtagagatca tcaatactgt ttttgaaaat gtagtggaca
    49981 tgtttacgga ttttcatttt catccgattg ggaaaaaaat caaagatatg gcagctggag
    50041 cagttttagt gaccgcttgt tttgctgtca tcattgggtt gattttattt gtccctaaaa
    50101 tatatcattt gttgtttaat taaaaaggag aacgtatatg ccagaacata aatcagggtt
    50161 tgtcgcaatc gtcggccgcc cgaatgtagg aaaatccaca ttattgaacc gaatcgtggg
    50221 tcaaaaaatt gccattatga gtgacaaggc acagacaact agaaataaaa tccaaggagt
    50281 atatactaca ccagaagctc agctgatttt tatcgataca ccaggaatcc ataaaccaaa
    50341 gcatcgtcta ggagatttta tggtagaagc agcttacagt gcgttgaaag aagtggatgc
    50401 agtcttattt atgatcagtg ctgatcaaaa acgcggccgg ggagacgatt ttattattga
    50461 acgtctaaaa aacgtgcatt ctccagttta tctgattatc aataaaatcg ataagatcca
    50521 tccagacgag ttgctgggaa tcatcgaaga ttattcgacg cagatgcctt ttgcacaagt
    50581 gattccgatc tctgctacag aaggaaacaa tgtcgaacgc ttaatggatg tattagtcag
    50641 tgaaatgcca gagggcccac aatattttcc agatgatcaa gtgactgatc atcctgaata
    50701 ctttatcgtt tctgaattga tccgtgagaa agtcttgttt ttaacacgag acgaagtgcc
    50761 tcattctgtc gcagtcgttg ttgattcgat gaagcgaaac gagaatgata aaatccatat
    50821 ccaggccacg atcatcgtcg aaagagatag ccaaaaagga atcattatcg gcaaaggcgg
    50881 aaaaatgctg aagcaagtag gaacgaaagc aagaaaggat atcgaaaatc ttttaggaga
    50941 caaagtattt ctagaacttt gggtcaaagt ccaaaaagac tggcgagaca aaaaagtcta
    51001 tctgcaagac tttggctacc gaaaagacga atactgatat tctgaacttc ttataggtta
    51061 agtatagaaa taaactggat aaaaatccgc acgttgagaa aaacggcgga agatcgaaac
    51121 ataaataatc tggatcggca gaatctgctt ttccagattt attttttagg agggagaata
    51181 tgagccagct tgcagaatcg aaaggcttga ttttatctag ccgtaattac aaagaaaaag
    51241 ataaattagt caaaatcttt acggaatctt ctggcaaaat gatgttttat atcaaaggaa
    51301 tccatcggca aaatcagcca ttagctccgg ctttgctccc ctttaccgaa gcagtctata
    51361 tcggtaattt tcgaagtgaa ggtttgtcgt ttttaagcag tgtcaaagac gtccatgcgt
    51421 ttcggaacat ccaagaagat atctttttga gcggttatgg tacctatttg ctaaatctag
    51481 tagatgcagc aatcgaagat catcaatatg acccgcattt attccaattt acgcaacaag
    51541 ctctgcagcg gatggatcaa ggagatgatg cagaaatcat cacgaatatc tttgaagttc
    51601 aaatactgca acgcttcgga atcgcgccaa tttggacgca ctgtgtcgta tgcggggaaa
    51661 caaaaggaaa atttgactat tcttccaaat ctggcggtgt gatatgcgag aaacactggc
    51721 caatggacga acaccgttat catgcagatc ctcgcgctgt ttatttcgtt cgaatgtttt
    51781 cggctatttc ttatgataag atcagtggaa tccacttgaa agaagaaacg aagcaggcaa
    51841 tccgtgacct cattgaccag ttgtatgatg aatatgtcgg tattcatcta aaaagcaaaa
    51901 agttcattga tcaaatgaag tcttgggcac acgtattaaa gacgccagag aaaaatatgc
    51961 ctgaaaaaga gatacctgaa aaagaagaat aaatgaaaga tacaacaaaa aaatcaaaac
    52021 tatttgacaa atacagggac ttccgtctat tattaaccgt agattaaata gatcgttcac
    52081 tgagaggatc tattatataa acaagaaaac tgcaaaatga atacgtacat tgaccaagat
    52141 cagtaaaaaa cacgtggttt agcgagttcg ggagagtgga agccggaccc aaacgatttt
    52201 tgaagaggca cttgcgagta cgataaatga agctgccgaa tctttattcg gaagtagggt
    52261 ggaaccgcga aattattcgt ccctatgtct gtaatcagac atagggactt tttgtcgttt
    52321 tctttcctgt attcttattg acagcaacgc ttaaaaattg aaaggggcaa aacagatgag
    52381 taaaaaattg accgtccaag atatgatttt aacattacaa aaattttggt catcaaacgg
    52441 ctgcatgctg atgcaagctt atgacacaga aaaaggagca ggtacgatga gcccatatac
    52501 attcttacgg gcaatcggac cggaaccatg gaatgctgct tatgtagagc catcccgccg
    52561 accagctgac gggcgttatg gagaaaaccc aaaccgtttg tatcagcatc atcaatttca
    52621 agtcgtaatg aaaccttcac ctgaaaatat ccaagagctt tatttagaaa gcttgcgtct
    52681 tttaggaatt gatccattag aacacgatat tcgttttgtt gaagacaact gggagaaccc
    52741 atcgatgggg tgtgccggtg tgggttggga agtatggctt gatgggatgg agatcacaca
    52801 attcacgtac ttccagcaag tcggaggact accttgtaaa ccagttactt ctgagatcac
    52861 ttatggacta gaacgtcttg cttcatatat tcaagaagtt gaaagtgtct atgatctgga
    52921 atgggctgat ggtgtgaaat atggcgagat cttcaaacaa ccagaatatg aacattccaa
    52981 atattctttt gaagtaagtg accaagactt gctactaagc aactttgacc gttttgaaaa
    53041 agaagctaaa cgctgtatcg atgaaaatct tgttcatcca gcgtatgatt atattttgaa
    53101 atgcagccat acattcaatt tattagatgc tcgcggtgca gtatccgtaa cagaacgagc
    53161 aggttatctt tcccgtatcc gcaacatggc tcgtgctgta gccaaaatct ttgtggcaga
    53221 acgcgaaaaa ttaggattcc ctttattgaa taaaaacaca gcaaatccag aaaacatgaa
    53281 ggaggctgaa taagatggca aaagacttat tacttgaaat cgggctggaa gaaatgcctg
    53341 ctcatgttgt cacaccaagc atgaaacaat tagaagaaaa aacagcaaaa tttttagatg
    53401 aaaaccaatt gacttatgat acgatcgaaa cgttttctac accgcgccgc ttagcaatca
    53461 aagtaacaaa cattccagaa cgtcaagcag acagcgaaga agaagtcaaa ggaccagcca
    53521 aaaaaattgc tttggacgca gatggaaact ggacgaaagc agctgaagga tttgtccgcg
    53581 gacaaggtct gacgacagat gctatcactt ttagagaatt aaaaggcgtg gaatatgtct
    53641 atgtaacgaa atacactcac ggcaaagaag caaaagaagt attgacaggt ttagcagatg
    53701 tcattaaaag cctcactttc ccagtaacga tgcactgggc agaatacgat tttgaatata
    53761 ttcgccctat tcactggatc gtggcattgt tagatgacga aataatcccg tttgagatct
    53821 tggatgtcaa aacagacaga gcttcaagag gtcatcgttt cttaggcgaa gatgtgacat
    53881 ttacgcatgc aaaagaatac gaagaaaaat tgaatgaaca atttgttatt gcttcaccgc
    53941 aaaaaagaaa agaaatgatc atcacacaag caaacgaatt agccgaaaaa aatcactgga
    54001 tcattgatct agatgaagat ttactagaag aagtcaacaa tttagtcgaa tatccaactg
    54061 tcttttctgg cgacttcgaa gaaaaatatc tatctgttcc tgaagaagta ctagtcactt
    54121 ctatgaaaga acatcaacgt tatttcgaag tacggaacga tcaaggtatg ttgcttcctc
    54181 attttatttc tgctcgtaat ggcgatcggg taaaattgga aaatgtggta cgaggcaatc
    54241 aaaaagtatt gacggctcgt ttagaagatg cggaattctt ttataatgaa gacaagaaag
    54301 cttcaatcga ccaatacgtt gaaaaattaa aaactgttac tttccatgaa aaaatcggta
    54361 gcatctatga gaaaatgcaa cgggtacaag tcatcgctcg catcataggc gaacaagtag
    54421 gactatctga ggaagaattg atggatctgc aacgcgctgc tgaaatctat aaatttgatc
    54481 tagtaaccaa catggtagga gaattccctg aactacaagg gatcatggga gaaaaatatg
    54541 ctctgctgaa aggcgagaaa ccagccgtag caacagcgat ccgtgaacat tacatgccta
    54601 tatccagtga aggagattta cctgagacta cagtaggttc tgttttagcg attgctgata
    54661 aattagatag tatcttttct ttctttgcag ttgggatgat cccaagtggc tcaaacgatc
    54721 catatgcttt gcgccgtcaa gcatatggtg tcgttcgaat catcgaatcg aaaaaatggg
    54781 cctttccttt gtctgttctg caagaaacga ttagtgaagt tatcagtaaa gatacggatc
    54841 gttttggcat tggcttgtca gcgggacaac aacaggtgat cgactttatc aaaggccgtc
    54901 tgcgccaatt attgacaacg aagaatatcc gtcatgatgt catcgaagct gttttgaatg
    54961 cagaacaaaa agatctgaca aaagtatttg cagcagcaca attgttcaag cagcatcttg
    55021 cagatgaaga cttcaaacca tcgatggaag ctttgacacg tgtcgtgaac ttagcgaaaa
    55081 aagcggagct tgaaaaacaa tcagaagtag accctgaact gttcgaaaac gaagcggaga
    55141 aagaactgca caaagcagta gaggcaatga aaacaagctt tgctgaccaa acgatcaacg
    55201 aaaattatga tcagcttgta agccttcgcc cactgatcga aaattatttt gatcagacga
    55261 tggtcatggc agaagaacca gcagtacgta agaaccgatt aacgcaatta agtcaaattg
    55321 ctgccatggc tttgtcacta gcaagtttag atcaaatcat cacaaaataa tttctaatat
    55381 gtaaataaac cagagaacag gcacaaaata ggctatttct ctg
//
LOCUS       DADVXK010000009        47242 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.009, whole genome shotgun sequence.
ACCESSION   DADVXK010000009 DADVXK010000000
VERSION     DADVXK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.009"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..434)
                     /locus_tag="KB909_000516"
     CDS             complement(<1..434)
                     /locus_tag="KB909_000516"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBB6836577.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
     gene            680..1627
                     /locus_tag="KB909_000517"
     CDS             680..1627
                     /locus_tag="KB909_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6836578.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(1838..3910)
                     /locus_tag="KB909_000518"
     CDS             complement(1838..3910)
                     /locus_tag="KB909_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6836579.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(3843..4220)
                     /locus_tag="KB909_000519"
     CDS             complement(3843..4220)
                     /locus_tag="KB909_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBB6836580.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(4349..4927)
                     /locus_tag="KB909_000520"
     CDS             complement(4349..4927)
                     /locus_tag="KB909_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6836581.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            5059..6351
                     /locus_tag="KB909_000521"
     CDS             5059..6351
                     /locus_tag="KB909_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6836582.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(6411..7529)
                     /locus_tag="KB909_000522"
     CDS             complement(6411..7529)
                     /locus_tag="KB909_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBB6836583.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="KB909_000523"
     CDS             complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="KB909_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBB6836584.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="KB909_000524"
     CDS             complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="KB909_000524"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBB6836585.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            10735..11334
                     /locus_tag="KB909_000525"
     CDS             10735..11334
                     /locus_tag="KB909_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBB6836586.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="KB909_000526"
     CDS             complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="KB909_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBB6836587.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(13029..13373)
                     /locus_tag="KB909_000527"
     CDS             complement(13029..13373)
                     /locus_tag="KB909_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBB6836588.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(13510..14655)
                     /locus_tag="KB909_000528"
     CDS             complement(13510..14655)
                     /locus_tag="KB909_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6836589.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(14835..15809)
                     /locus_tag="KB909_000529"
     CDS             complement(14835..15809)
                     /locus_tag="KB909_000529"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6836590.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(15889..16764)
                     /locus_tag="KB909_000530"
     CDS             complement(15889..16764)
                     /locus_tag="KB909_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBB6836591.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            16894..18801
                     /locus_tag="KB909_000531"
     CDS             16894..18801
                     /locus_tag="KB909_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBB6836592.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(19342..22620)
                     /locus_tag="KB909_000532"
     CDS             complement(19342..22620)
                     /locus_tag="KB909_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBB6836593.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(22891..23436)
                     /locus_tag="KB909_000533"
     CDS             complement(22891..23436)
                     /locus_tag="KB909_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6836594.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(23448..24140)
                     /locus_tag="KB909_000534"
     CDS             complement(23448..24140)
                     /locus_tag="KB909_000534"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBB6836595.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(24159..24443)
                     /locus_tag="KB909_000535"
     CDS             complement(24159..24443)
                     /locus_tag="KB909_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836596.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(24456..25019)
                     /locus_tag="KB909_000536"
     CDS             complement(24456..25019)
                     /locus_tag="KB909_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6836597.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            25247..25909
                     /locus_tag="KB909_000537"
     CDS             25247..25909
                     /locus_tag="KB909_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBB6836598.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            26033..27229
                     /locus_tag="KB909_000538"
     CDS             26033..27229
                     /locus_tag="KB909_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBB6836599.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(27330..28706)
                     /locus_tag="KB909_000539"
     CDS             complement(27330..28706)
                     /locus_tag="KB909_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6836600.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(28743..29610)
                     /locus_tag="KB909_000540"
                     /pseudo
     CDS             complement(28743..29610)
                     /locus_tag="KB909_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
     gene            complement(29699..30724)
                     /locus_tag="KB909_000541"
     CDS             complement(29699..30724)
                     /locus_tag="KB909_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6836601.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(30742..31416)
                     /locus_tag="KB909_000542"
     CDS             complement(30742..31416)
                     /locus_tag="KB909_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6836602.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(31600..32493)
                     /locus_tag="KB909_000543"
     CDS             complement(31600..32493)
                     /locus_tag="KB909_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6836603.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(32567..34264)
                     /locus_tag="KB909_000544"
     CDS             complement(32567..34264)
                     /locus_tag="KB909_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6836604.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(34257..35570)
                     /locus_tag="KB909_000545"
     CDS             complement(34257..35570)
                     /locus_tag="KB909_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6836605.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(35570..39607)
                     /locus_tag="KB909_000546"
     CDS             complement(35570..39607)
                     /locus_tag="KB909_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6836606.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(39620..40078)
                     /locus_tag="KB909_000547"
     CDS             complement(39620..40078)
                     /locus_tag="KB909_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6836607.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(40376..40894)
                     /locus_tag="KB909_000548"
     CDS             complement(40376..40894)
                     /locus_tag="KB909_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6836608.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(40896..41513)
                     /locus_tag="KB909_000549"
     CDS             complement(40896..41513)
                     /locus_tag="KB909_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6836609.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(41510..42364)
                     /locus_tag="KB909_000550"
     CDS             complement(41510..42364)
                     /locus_tag="KB909_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6836610.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(42361..43272)
                     /locus_tag="KB909_000551"
     CDS             complement(42361..43272)
                     /locus_tag="KB909_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836611.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(43313..44647)
                     /locus_tag="KB909_000552"
     CDS             complement(43313..44647)
                     /locus_tag="KB909_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6836612.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            44855..45685
                     /locus_tag="KB909_000553"
     CDS             44855..45685
                     /locus_tag="KB909_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBB6836613.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(45929..46247)
                     /locus_tag="KB909_000554"
                     /pseudo
     CDS             complement(45929..46247)
                     /locus_tag="KB909_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46369..46563)
                     /locus_tag="KB909_000555"
     CDS             complement(46369..46563)
                     /locus_tag="KB909_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836614.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
BASE COUNT        13646 a        10124 c         8379 g        15093 t
ORIGIN      
        1 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
       61 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
      121 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
      181 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
      241 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
      301 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
      361 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
      421 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
      481 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
      541 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
      601 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
      661 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
      721 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
      781 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
      841 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
      901 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
      961 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     1021 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     1081 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     1141 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     1201 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     1261 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     1321 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     1381 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     1441 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     1501 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     1561 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     1621 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     1681 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     1741 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     1801 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     1861 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     1921 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     1981 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     2041 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     2101 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     2161 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     2221 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     2281 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     2341 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     2401 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     2461 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     2521 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     2581 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     2641 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     2701 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     2761 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     2821 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     2881 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     2941 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     3001 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     3061 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     3121 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     3181 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     3241 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     3301 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     3361 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     3421 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     3481 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     3541 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     3601 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     3661 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     3721 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     3781 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     3841 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     3901 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     3961 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     4021 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     4081 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     4141 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     4201 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     4261 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     4321 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     4381 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     4441 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     4501 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     4561 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     4621 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     4681 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     4741 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     4801 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     4861 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     4921 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     4981 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     5041 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     5101 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     5161 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     5221 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     5281 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     5341 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     5401 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     5461 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     5521 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     5581 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     5641 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     5701 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     5761 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     5821 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     5881 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     5941 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     6001 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     6061 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     6121 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     6181 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     6241 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     6301 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     6361 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     6421 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     6481 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     6541 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     6601 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     6661 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     6721 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     6781 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     6841 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     6901 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     6961 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     7021 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     7081 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     7141 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     7201 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     7261 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     7321 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     7381 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     7441 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     7501 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     7561 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     7621 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     7681 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     7741 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     7801 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     7861 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     7921 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     7981 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     8041 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     8101 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     8161 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     8221 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     8281 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     8341 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     8401 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     8461 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     8521 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     8581 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     8641 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     8701 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
     8761 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
     8821 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
     8881 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
     8941 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
     9001 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
     9061 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
     9121 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
     9181 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
     9241 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
     9301 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
     9361 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
     9421 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
     9481 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
     9541 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
     9601 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
     9661 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
     9721 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
     9781 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
     9841 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
     9901 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
     9961 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    10021 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    10081 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    10141 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    10201 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    10261 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    10321 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    10381 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    10441 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    10501 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    10561 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    10621 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    10681 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    10741 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    10801 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    10861 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    10921 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    10981 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    11041 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    11101 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    11161 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    11221 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    11281 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    11341 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    11401 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    11461 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    11521 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    11581 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    11641 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    11701 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    11761 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    11821 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    11881 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    11941 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    12001 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    12061 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    12121 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    12181 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    12241 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    12301 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    12361 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    12421 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    12481 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    12541 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    12601 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    12661 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    12721 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    12781 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    12841 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    12901 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    12961 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    13021 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    13081 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    13141 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    13201 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    13261 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    13321 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    13381 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    13441 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    13501 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    13561 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    13621 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    13681 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    13741 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    13801 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    13861 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    13921 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    13981 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    14041 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    14101 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    14161 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    14221 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    14281 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    14341 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    14401 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    14461 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    14521 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    14581 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    14641 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    14701 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    14761 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    14821 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    14881 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    14941 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    15001 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    15061 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    15121 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    15181 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    15241 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    15301 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    15361 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    15421 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    15481 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    15541 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    15601 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    15661 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    15721 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    15781 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    15841 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    15901 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    15961 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    16021 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    16081 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    16141 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    16201 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    16261 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    16321 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    16381 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    16441 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    16501 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    16561 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    16621 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    16681 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    16741 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    16801 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    16861 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    16921 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    16981 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    17041 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    17101 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    17161 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    17221 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    17281 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    17341 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    17401 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    17461 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    17521 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    17581 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    17641 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    17701 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    17761 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    17821 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    17881 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    17941 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    18001 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    18061 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    18121 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    18181 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    18241 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    18301 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    18361 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    18421 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    18481 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    18541 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    18601 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    18661 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    18721 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    18781 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    18841 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    18901 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    18961 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    19021 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    19081 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    19141 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    19201 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    19261 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    19321 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    19381 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    19441 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    19501 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    19561 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    19621 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    19681 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    19741 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    19801 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    19861 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    19921 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    19981 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    20041 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    20101 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    20161 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    20221 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    20281 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    20341 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    20401 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    20461 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    20521 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    20581 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    20641 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    20701 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    20761 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    20821 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    20881 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    20941 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    21001 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    21061 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    21121 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    21181 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    21241 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    21301 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    21361 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    21421 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    21481 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    21541 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    21601 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    21661 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    21721 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    21781 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    21841 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    21901 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    21961 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    22021 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    22081 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    22141 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttagg
    22201 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    22261 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    22321 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    22381 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    22441 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    22501 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    22561 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    22621 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    22681 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    22741 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    22801 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    22861 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    22921 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    22981 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    23041 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    23101 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    23161 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    23221 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    23281 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    23341 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    23401 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    23461 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    23521 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    23581 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    23641 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    23701 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    23761 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    23821 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    23881 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    23941 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    24001 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    24061 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    24121 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    24181 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    24241 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    24301 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    24361 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    24421 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    24481 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    24541 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    24601 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    24661 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    24721 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    24781 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    24841 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    24901 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    24961 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    25021 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    25081 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    25141 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    25201 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    25261 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    25321 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    25381 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    25441 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    25501 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    25561 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    25621 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    25681 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    25741 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    25801 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    25861 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    25921 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    25981 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    26041 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    26101 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    26161 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    26221 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    26281 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    26341 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    26401 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    26461 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    26521 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    26581 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    26641 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    26701 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    26761 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    26821 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    26881 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    26941 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    27001 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    27061 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    27121 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    27181 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    27241 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    27301 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    27361 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    27421 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    27481 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    27541 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    27601 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    27661 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    27721 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    27781 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    27841 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    27901 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    27961 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    28021 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    28081 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    28141 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    28201 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    28261 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    28321 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    28381 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    28441 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    28501 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    28561 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    28621 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    28681 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    28741 gattaaactg ttttcatata ccctaaaagg gataccacct aaaatgacta aaaggcaacc
    28801 aacaataaca taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc
    28861 taaagtagag ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga
    28921 tttgactgtt agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt
    28981 tttccacaca aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat
    29041 cattccgata ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat
    29101 gatggtatat acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa
    29161 atcaagcatt ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata
    29221 cgcaccgctt acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt
    29281 ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga
    29341 caatggtagc cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc
    29401 aacactccaa gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg
    29461 actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt
    29521 ttgttgattg gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa
    29581 catagggact aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag
    29641 aaacttatca gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct
    29701 aacgtttttc attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc
    29761 cttcagttga ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat
    29821 aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct
    29881 tatcaaagat ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa
    29941 ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat
    30001 atttgatggc attactaagc aattggttga agataaaagc gatccattta gcatcggtca
    30061 aaacagtatg atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg
    30121 cctgactgcg tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt
    30181 cccgcgagaa actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt
    30241 ttgataattc attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac
    30301 gaactagcaa tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat
    30361 aatctttttg gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga
    30421 tcagctgatt gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat
    30481 aattttgcaa aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc
    30541 tcaagtaacc acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag
    30601 caattgtgct caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg
    30661 caataaaaaa cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat
    30721 tcatcttaac cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat
    30781 atatccttgg atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa
    30841 tgtattgtca tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact
    30901 taagatcttt ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa
    30961 atcaatgatc tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt
    31021 gtggctcatc atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt
    31081 gatttttgca atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat
    31141 gttcatagcc atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac
    31201 tttcgatact tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat
    31261 atctagtaat acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc
    31321 ggtcgttcca aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat
    31381 gatctcttcg tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct
    31441 tgctactaca atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat
    31501 tttagcaaac gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag
    31561 cagcttaaat ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg
    31621 ttgtttttgt cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa
    31681 tatacctaga aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt
    31741 tgaagagact tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt
    31801 cacggtgtaa ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa
    31861 tgtatttgtt tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg
    31921 accatacact tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag
    31981 ttttttctca gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt
    32041 tggaaaagag gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc
    32101 atcaaataaa ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg
    32161 ttcgtaatat tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt
    32221 gacttgtccc attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg
    32281 cactgctaat tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt
    32341 ctcgatcctt ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa
    32401 aactgcagct ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg
    32461 ggtttgaggt ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac
    32521 tgcagcaacc tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact
    32581 tcattttaga tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta
    32641 agaatgccaa gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta
    32701 ctctttctgg ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat
    32761 aagagatgat aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg
    32821 ccatggtctc tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat
    32881 ttccatctgc gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc
    32941 ctgattcata aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt
    33001 cttcattcca caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt
    33061 tttcaaactt tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat
    33121 caaattcatc atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt
    33181 ctagttctgt ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg
    33241 ctaatctacc taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga
    33301 caaacccgtt gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc
    33361 cggctcgcac ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga
    33421 ttttgtaatt tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa
    33481 taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg
    33541 tttcttgttc tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat
    33601 tcatctgttt atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt
    33661 atgtgtcttt ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg
    33721 gcatcataac aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta
    33781 agaaaagata gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga
    33841 ataccgcttc tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta
    33901 aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac
    33961 cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta
    34021 cgtcaaacaa atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca
    34081 atccgctatt cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg
    34141 tcacttcact tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa
    34201 tccctattcc cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat
    34261 tcattttttt ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt
    34321 cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct
    34381 gattgacctg gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg
    34441 gtctcgttat aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat
    34501 tctaattcag ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc
    34561 acccaaaatt cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct
    34621 tccacacctt ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc
    34681 gtaacaaggc cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca
    34741 ttgtctgctg gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa
    34801 tatttccccc cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct
    34861 ttttcagttg ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg
    34921 acatttttag gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa
    34981 attggcaaaa tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact
    35041 tctggatcaa tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta
    35101 ggtgctttga tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt
    35161 accgaagtcc ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg
    35221 ttcgtttcag cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt
    35281 tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc
    35341 tgtgaaatga tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca
    35401 tggtattcaa attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat
    35461 tccacgacat cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca
    35521 agcggtagta aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc
    35581 cctccttttt agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga
    35641 atgcagcaag caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt
    35701 caggatcgtt cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt
    35761 ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa
    35821 cttttagtgt acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt
    35881 ctcgataact aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact
    35941 tcacttcctt gatccgatag accccttcca acaagtctga agcattgaat agggaagaat
    36001 cgtttggatc tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt
    36061 tctcaattga aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa
    36121 gttccaaatc gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga
    36181 tttcatagcc ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa
    36241 acttaccttc ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg
    36301 gtgcgacaga ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat
    36361 ttaaatcgac atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca
    36421 aacgtttcga ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg
    36481 aagaatcccc cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt
    36541 ctaattttct aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc
    36601 ataaacgatc ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt
    36661 gcttgagttg gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt
    36721 catcaggttc tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt
    36781 tggtagtttc ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa
    36841 ctttctcacc atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc
    36901 tccctttctc ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga
    36961 tttccagtcc gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat
    37021 tactgccttc aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt
    37081 ccagtttgac atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag
    37141 aaagcttgtg atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga
    37201 ctctcgaacc agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt
    37261 tggctgcata ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg
    37321 gtccagcgat ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa
    37381 tcggcatctt cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg
    37441 gttcggcttc cccactctct ggattttggt catataatgc aaattcgact ccagccaacg
    37501 gctcgccatt ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa
    37561 tggaagaaga tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt
    37621 tctgaatata ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa
    37681 gttttacttg gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt
    37741 tataagcttg gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg
    37801 cttgtccatg acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc
    37861 ctggatctag atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat
    37921 taaaaccagt ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga
    37981 tatcctccaa ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta
    38041 cgccatcttc ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc
    38101 gttgtctccc gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt
    38161 tctcttgata cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact
    38221 tttcttgcga agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt
    38281 gagtcgcttt attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat
    38341 cttctggacg gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag
    38401 tattcccaga aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat
    38461 cttccatcac agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa
    38521 tcggtgcata actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat
    38581 ttctattttc tccgccattg tctttataca atgtttcata gccattttta agccctagtg
    38641 taagcggagt tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac
    38701 gattgatatc atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag
    38761 ctgtactatt atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga
    38821 gcagatcttt actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat
    38881 tggtcccagc ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga
    38941 ttggactgat ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg
    39001 ttgcatcttc aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt
    39061 ttttgatgta cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc
    39121 aaagctgaac ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat
    39181 tagtagcata gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga
    39241 tcaagttctc tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg
    39301 tccaatttcc taacactttt gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt
    39361 cgttttcaac ttctccgcta ggatagatat attcataggg gtcttgcgta gctgttggcc
    39421 caagacgctc caaaataccg ttgaataact ggcgttgaat gcgctggagt gcttgaccgc
    39481 tgggtacgat tggttcgtcc agcttttcca tctcattttc ttcgctacgt tgaatttcag
    39541 cggaatcttc tgtatcagtt tcattttctt gtaattcttg gttatctatt ctttcatcaa
    39601 ccaccacttg aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa
    39661 tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat
    39721 cgatcgtctc gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac
    39781 gaacgttttt tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac
    39841 cttcattggc actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt
    39901 caatatactt cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg
    39961 tttctgttga ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg
    40021 gtccaaatag caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat
    40081 ccttatactc ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca
    40141 tctaattata atttaattta attttaattt taaatcaaat gatatccttt ttagttaaaa
    40201 aacaccaatt atacaacatt tattattaaa attaaattat aaaattttat aacgttctca
    40261 tttaacaaaa cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa
    40321 aaaaataaag cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga
    40381 taacggcagc gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag
    40441 taggataatg taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg
    40501 ctaatattcc tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg
    40561 ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac
    40621 gatttttttc ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa
    40681 aaaaatagat caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca
    40741 agactaaaac agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa
    40801 atttcaaaaa attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa
    40861 tactatcatc gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt
    40921 tcttgcgtac gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat
    40981 aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc
    41041 aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa
    41101 gcttcttttt gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga
    41161 agcaaaaaca acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa
    41221 atctgataat cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca
    41281 taaagagaga agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca
    41341 ttttttttgt aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa
    41401 acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca
    41461 atgatttcta agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg
    41521 aacctcctgt caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa
    41581 tcgtcgggat caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt
    41641 ggttctgaaa aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata
    41701 acagaggacc taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca
    41761 aggcaggttt cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt
    41821 cgatttcagc agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa
    41881 atatattgaa cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc
    41941 agccgatctt ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca
    42001 tcgtagaaag aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc
    42061 cataagcaat aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata
    42121 atgtatttct tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc
    42181 atacgatttt ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca
    42241 atgaagtaaa caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga
    42301 ggacataact tagtattttt tttgtttgcc gattcacact ggtctttttg aaataatcca
    42361 tcatttgccg tcacctccag aataatagac ccacttaggt gcaagcttca aattgacaaa
    42421 cgtcagaacc aacacgatca gaaacaggat cattgacata gccatcgcat aacccatatc
    42481 aaaagctacg aacgccttgt tccacatatg cagattataa aaaagcaaag aatttgcagg
    42541 tccgcctgtt ccatttttcg tcatgacata agcttcttga aaaatttgga aagaaccgat
    42601 cgtagaggtg atcacatcgt aaaaaataat aggagtgatt aatggcaaag taatactttt
    42661 gaactttccc caaacgcctg ctccatcgat ttctgctgat tcatataaag atctaggaac
    42721 attttgtaat gtagctaagt aaagtagcat tgctcctcca gaactccata ttttcatcaa
    42781 aatcaacgca ggtttcgtcc attgtggatc aaacagccaa gctggtccag ggatatggaa
    42841 ccagcccaga aatgtgttga tcaatcctgc agatggagaa agcagctgca tccataagat
    42901 gtagactgct actcctgata agactgccgg taaatagaaa gctgtacgga atacactgat
    42961 tcctttgatt ttttgattga gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg
    43021 tacattgaag atgacgaaat aaacggtgtt gtataacgat ttccaaaata aatcatcgtg
    43081 aacgaacatt cttttgaaat ttgctagacc aatgaaattc atcttggatg tcaaattata
    43141 atcggtgaaa ctaccaataa ctgaaaaaag cataggccct agcataaata ccaagaaccc
    43201 gataataaaa ggcgagataa ataaataggc ccatcttgct tcttttttct ttcggataga
    43261 taaacgcttc aaattttctt gcctcctctg tacctagaca gtcaaaaatg gattattgat
    43321 tttgcttgac taagttttct actgcttttt gtgcatctgc caatccttct tttggtgatt
    43381 ttgttcctaa aagaatctgg tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat
    43441 ctaaaggaac tggtgtgatc accgtatttt taaagttttc gtccgccatt tgatagatca
    43501 tttttccttt atccgttagg ttgtcattat tcactaaatt ctcattggct gtcttgctcg
    43561 ccatgatatc aaaacttttt tcgccgaatt tttcttgtac ttctggagaa gaaagatatt
    43621 tgatgaattc ataagaggcc tcaggatctt ttgctccgta tggtacttcc aagacgaatc
    43681 cgccacccca cgaccaatgg cctgaacctt cttctttttc tgggagctgc atcacgccaa
    43741 aatcaaaatc atccggtgca ttttccatca aactagagta ataattgata ttttgggcac
    43801 gcatggctac taatccggaa ataaatggat cagatacacc agacccaaat tcggcttcta
    43861 atttattgat cgtatttttc ccataataat cttgccagtc ttggatccac tccaaggctt
    43921 ccactttatt tttagtatca atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt
    43981 tatctgcgtt tagcgcccat acatcagccc ctaaattcca taatggataa aaaccgatgc
    44041 gtgtaaattc ttttccttct tttttatcta gtttacgtgc tgtttcttct aattcatccc
    44101 aagttgtcgg tagatcttgt tcactgattc cagcttcttt aaataacttt ttattataaa
    44161 aaatgacttg tgtatctgta ttgaatggga tcgcataagg atcaccttca tattctactg
    44221 tatcccaaag ctgcggataa aaatccttag aagtgtcttt ttctacatat ttggagagat
    44281 tagttgcttg ctgtgcttct gctctttggg caacggaatt tatgtcctgt acaataacat
    44341 cgggtgcatt tccagctgtt attgcagata aagatttagt ccagatgtca ccccatggct
    44401 gatacttata atttacatgg atctcgtttt gtgattgatt gaaatcctca atgatttctt
    44461 cgatagcttc ttttcgtgca ccggatcccc aaaaggacca gaaatcaata ttttttcttc
    44521 catcacttgt tttttcagaa gaatttgctg cacttgaact ggcatcgctt gcattacttg
    44581 atccgcatcc tcctaataaa aacaatgctg aacttgccag caaccctgta aacaataatt
    44641 ttttcatatt ttacctccaa attttaatgt aaccgatgcc ggttttaata taacgatatc
    44701 attttgttct gaaaataaca atttataagg tatgattcta aaaaaattat taatgatacc
    44761 aatactttat ataattcgcg agcgctttct ttgaattttt taatctttcg tagcagaatg
    44821 agaatgtatt aaaaatagat taggaggaat tttgatgttt agacaccaga aagaattgca
    44881 gtttgaagca aaaccagatc gtccgaatcc attaatcgcg aaatatctgc aggagctgat
    44941 cggcggccaa tatggcgaga tgagtgtagc tatgcagtac ctgttccaag gctggagctg
    45001 ccgaggagaa gaaaaatata aagatatgct gatggacatt gcaacagaag aaatcggcca
    45061 cgtggaaatg ttggcgacaa tggttgctcg tttattagag ggtgcgcctg ttgaagatca
    45121 agaagcagcg atgcaaaaag atccaacaat cggtgccatt atctctggaa tgaatccaca
    45181 gcacgcgatc gtagctggct taggacctcg tcctgctgac agcgtgggca atccatggag
    45241 cggtgcctat atcattgcga gtggcaactt gttagcagac tttagagcta atttaaatgc
    45301 cgaatcacaa ggaagacttc aagtagcacg tatttacgaa atgatcgatg atcgtggcgt
    45361 aaaagatatg ctgtctgttc tccttgcaag agatagctat catcaaaatc tatgggaatg
    45421 tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg
    45481 tgacaaagaa cgaaaagaca ttgcttatga cttctataac ttctcagagg gagaccaaag
    45541 tagtgaaggt tcttgggcta gtggcaaagc actggatggc gaaggcgaat atcaatggtt
    45601 gaaagaacct aagatcgaag gcgctgcacc aaaattagaa ccagtaacac caaaaatgta
    45661 tgggacacct ccattcaaga aataaatatc tacccgtaga aacacccgtt ttttgttcca
    45721 cacgctttgt gagcaaaact gactaaagtc attaatcata accacccttc aaaagggtgg
    45781 ttttctctag agctataagc tcaaatcacc ggccagcgcc taaagacgct ggctttcata
    45841 ttttatgttc aagccatatt gcctttgcca gttttgccca cctcttaaaa ggtttatgta
    45901 ctactcctta gcccttaaaa ggatcgtctt actctcgtac actcagctta tctaacgcac
    45961 tatcatgttt ttcttgttct tgaatgtact ttttgatggt cgcttcattt tgtcctactt
    46021 ttgtcacata gtatccttcc acccaaaagt gtcgataccc aaatttatat tttagatttg
    46081 cacaatctct tgatgatctc ctgaatattg gctcgatatt gattataaat tatttttctt
    46141 ctatactttg gtgtgaatac aatgtggtat ttacacatct actttgtacg ggctaaacta
    46201 tttcccttta ttgctccacc cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc
    46261 tcaattaggt ctaaagacaa taaatctaaa aacccgctgc ttcactgaca gaaacaacgg
    46321 gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc aatctatttt atttttttga
    46381 ttttttataa atggaaaatg cttcaagaag tccaagaaat aaagccgtat aaaaacaaga
    46441 acctatgaaa tctttattta ttagatattc aacagaaatc ccgataacac tagccaacaa
    46501 tatatttatc agaagtgtaa aataaggatg ctttttatag aatagaacta gtgttgtttt
    46561 catagactct cctttcttca tatttccaat taatcacaaa ttcacggcat tactagaaaa
    46621 attaaagggg cgcagaagtg gaaaaatact cttcgacttt ccctacaaac caggccatct
    46681 tgtgtttaat aactatacca aatctaaggt acctctaaat ctaaattcca tttgtggcgg
    46741 tgacctccaa tttttaactc ttctatctcc catccagtat acataacctt gatacttcga
    46801 ccacttatat atcgaacaca caaataccta tccattgcag gagtactacc taacttagtt
    46861 gctacttgca tctaaataac agctgaaaag ataggactta ctcttagtaa agtatctgaa
    46921 ctattaattt ttaaactatc atttttatcc tcaactacat gcacatctgt tgcaacttca
    46981 ctttctgtct catccagata aatgattaag gaatcgggaa ttgcaatatc ttcagctgac
    47041 gctggaatag ttgagctaaa ttagtcatca tatctttatt ataaaataac caacagcaaa
    47101 aaatacaatg aaaaacaaac ttggaactaa tgtatcatta ataaatgttg aaaaattcag
    47161 caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa aagctaataa
    47221 gatggttagg aatcctttag aa
//
LOCUS       DADVXK010000010        44564 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.010, whole genome shotgun sequence.
ACCESSION   DADVXK010000010 DADVXK010000000
VERSION     DADVXK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.010"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            146..793
                     /locus_tag="KB909_000556"
     CDS             146..793
                     /locus_tag="KB909_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBB6836615.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            808..2334
                     /locus_tag="KB909_000557"
     CDS             808..2334
                     /locus_tag="KB909_000557"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBB6836616.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(2383..5181)
                     /gene="ileS"
                     /locus_tag="KB909_000558"
     CDS             complement(2383..5181)
                     /gene="ileS"
                     /locus_tag="KB909_000558"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBB6836617.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(5443..6150)
                     /locus_tag="KB909_000559"
     CDS             complement(5443..6150)
                     /locus_tag="KB909_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBB6836618.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            complement(6171..6953)
                     /locus_tag="KB909_000560"
     CDS             complement(6171..6953)
                     /locus_tag="KB909_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBB6836619.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            complement(7002..7289)
                     /locus_tag="KB909_000561"
     CDS             complement(7002..7289)
                     /locus_tag="KB909_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBB6836620.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            complement(7304..7903)
                     /locus_tag="KB909_000562"
     CDS             complement(7304..7903)
                     /locus_tag="KB909_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBB6836621.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            complement(7917..8594)
                     /locus_tag="KB909_000563"
     CDS             complement(7917..8594)
                     /locus_tag="KB909_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBB6836622.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            complement(8611..9852)
                     /gene="ftsZ"
                     /locus_tag="KB909_000564"
     CDS             complement(8611..9852)
                     /gene="ftsZ"
                     /locus_tag="KB909_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBB6836623.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            complement(9875..11200)
                     /gene="ftsA"
                     /locus_tag="KB909_000565"
     CDS             complement(9875..11200)
                     /gene="ftsA"
                     /locus_tag="KB909_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBB6836624.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            complement(11356..12576)
                     /locus_tag="KB909_000566"
     CDS             complement(11356..12576)
                     /locus_tag="KB909_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBB6836625.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            complement(12591..13679)
                     /gene="murG"
                     /locus_tag="KB909_000567"
     CDS             complement(12591..13679)
                     /gene="murG"
                     /locus_tag="KB909_000567"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBB6836626.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            complement(13705..15066)
                     /locus_tag="KB909_000568"
     CDS             complement(13705..15066)
                     /locus_tag="KB909_000568"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBB6836627.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            complement(15080..16042)
                     /locus_tag="KB909_000569"
     CDS             complement(15080..16042)
                     /locus_tag="KB909_000569"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBB6836628.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            complement(16068..18260)
                     /locus_tag="KB909_000570"
     CDS             complement(16068..18260)
                     /locus_tag="KB909_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6836629.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            complement(18261..18662)
                     /gene="ftsL"
                     /locus_tag="KB909_000571"
     CDS             complement(18261..18662)
                     /gene="ftsL"
                     /locus_tag="KB909_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6836630.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            complement(18667..19626)
                     /gene="rsmH"
                     /locus_tag="KB909_000572"
     CDS             complement(18667..19626)
                     /gene="rsmH"
                     /locus_tag="KB909_000572"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBB6836631.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            complement(19647..20078)
                     /gene="mraZ"
                     /locus_tag="KB909_000573"
     CDS             complement(19647..20078)
                     /gene="mraZ"
                     /locus_tag="KB909_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBB6836632.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            complement(20248..20616)
                     /locus_tag="KB909_000574"
     CDS             complement(20248..20616)
                     /locus_tag="KB909_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBB6836633.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            20787..21743
                     /locus_tag="KB909_000575"
     CDS             20787..21743
                     /locus_tag="KB909_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6836634.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            21816..21932
                     /locus_tag="KB909_000576"
     CDS             21816..21932
                     /locus_tag="KB909_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBB6836635.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(21987..23669)
                     /gene="recN"
                     /locus_tag="KB909_000577"
     CDS             complement(21987..23669)
                     /gene="recN"
                     /locus_tag="KB909_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBB6836636.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(23687..24136)
                     /locus_tag="KB909_000578"
     CDS             complement(23687..24136)
                     /locus_tag="KB909_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6836637.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(24243..25061)
                     /locus_tag="KB909_000579"
     CDS             complement(24243..25061)
                     /locus_tag="KB909_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBB6836638.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(25070..25960)
                     /locus_tag="KB909_000580"
     CDS             complement(25070..25960)
                     /locus_tag="KB909_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6836639.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(25962..26186)
                     /locus_tag="KB909_000581"
     CDS             complement(25962..26186)
                     /locus_tag="KB909_000581"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBB6836640.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(26191..27528)
                     /locus_tag="KB909_000582"
     CDS             complement(26191..27528)
                     /locus_tag="KB909_000582"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBB6836641.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(27529..28383)
                     /locus_tag="KB909_000583"
     CDS             complement(27529..28383)
                     /locus_tag="KB909_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBB6836642.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(28480..28929)
                     /gene="nusB"
                     /locus_tag="KB909_000584"
     CDS             complement(28480..28929)
                     /gene="nusB"
                     /locus_tag="KB909_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBB6836643.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(28922..29347)
                     /locus_tag="KB909_000585"
     CDS             complement(28922..29347)
                     /locus_tag="KB909_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6836644.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(29593..30657)
                     /locus_tag="KB909_000586"
     CDS             complement(29593..30657)
                     /locus_tag="KB909_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6836645.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(30829..31074)
                     /locus_tag="KB909_000587"
     CDS             complement(30829..31074)
                     /locus_tag="KB909_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6836646.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(31213..31587)
                     /locus_tag="KB909_000588"
     CDS             complement(31213..31587)
                     /locus_tag="KB909_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBB6836647.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(31670..32584)
                     /locus_tag="KB909_000589"
     CDS             complement(31670..32584)
                     /locus_tag="KB909_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBB6836648.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(32605..33408)
                     /locus_tag="KB909_000590"
     CDS             complement(32605..33408)
                     /locus_tag="KB909_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBB6836649.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(33441..34430)
                     /gene="manX"
                     /locus_tag="KB909_000591"
     CDS             complement(33441..34430)
                     /gene="manX"
                     /locus_tag="KB909_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBB6836650.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(34533..35024)
                     /locus_tag="KB909_000592"
     CDS             complement(34533..35024)
                     /locus_tag="KB909_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6836651.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(35215..38022)
                     /locus_tag="KB909_000593"
     CDS             complement(35215..38022)
                     /locus_tag="KB909_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6836652.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            complement(38456..38749)
                     /gene="rpmA"
                     /locus_tag="KB909_000594"
     CDS             complement(38456..38749)
                     /gene="rpmA"
                     /locus_tag="KB909_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBB6836653.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(38762..39106)
                     /locus_tag="KB909_000595"
     CDS             complement(38762..39106)
                     /locus_tag="KB909_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBB6836654.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(39133..39441)
                     /gene="rplU"
                     /locus_tag="KB909_000596"
     CDS             complement(39133..39441)
                     /gene="rplU"
                     /locus_tag="KB909_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBB6836655.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     misc_feature    complement(39461..39537)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            39723..40364
                     /locus_tag="KB909_000597"
     CDS             39723..40364
                     /locus_tag="KB909_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6836656.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(40426..42057)
                     /locus_tag="KB909_000598"
     CDS             complement(40426..42057)
                     /locus_tag="KB909_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBB6836657.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(42180..42539)
                     /locus_tag="KB909_000599"
     CDS             complement(42180..42539)
                     /locus_tag="KB909_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBB6836658.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            complement(42698..42771)
                     /locus_tag="KB909_000600"
     tRNA            complement(42698..42771)
                     /locus_tag="KB909_000600"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42735..42737),aa:Arg,seq:tct)
     gene            complement(43080..43763)
                     /locus_tag="KB909_000601"
     CDS             complement(43080..43763)
                     /locus_tag="KB909_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBB6836659.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            complement(43891..44409)
                     /locus_tag="KB909_000602"
     CDS             complement(43891..44409)
                     /locus_tag="KB909_000602"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6836660.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
BASE COUNT        12629 a         9652 c         7518 g        14765 t
ORIGIN      
        1 agaatgagtc ttctctatca tctttcgttt tttgttgtaa aaacgtctaa aaatcctttg
       61 ttttttattt agaaaaatag tcaattaacg ttttttttgt tacacttact aatgatggtt
      121 ttttaccatg aaaggatgat cgaatatgac accaaatcga gaagattatt tgaaaatcat
      181 tttagaacta ggtggagata caacgaaagt caacaataaa caaatcgtat ctagtctaga
      241 tgtctcagct gcatctgtca gtgaaatgat ttctaaactt gtgaaagaag agcttgtaga
      301 acattcccct tatcaaggtg tacaattgac tgcaagcgga ctgcaaaaag ctagcagtct
      361 gattcgcaaa catcgcttat gggaagtttt tttagttgaa catttagact atagctggaa
      421 tgaagtccat gatgatgctg aagtattgga acatgtgact tcggaacatc ttgcagatca
      481 tttagaaaac tatttgaatc atcctgaaca ttgtcctcat ggaggatcga ttcctaaaaa
      541 agaggaagtt gtccatgaag aacgccgaca aacattggag tcctatcctg tcggtacaaa
      601 agtgcgtatc gcacgagtgc ttgatgaaaa agaattgttg gattacttag tcactattga
      661 cctgaatatc aacgaagaat atgagatcgt tgacatcgca gcttatgaag gaccgatcac
      721 tatccaaaat gatagaaaga aaatccccgt cagctttaag gcggccagca cgatttttgt
      781 cgataaaata taaaggagtg tatccacatg tctaatgaaa aaaatgtatt gtttacgata
      841 ttcggcggta caggtgacct agcccagcgt aaattgtacc cgtctttgtt ccgcctttac
      901 agaaaaggaa atttaggcga gcattttgct gtaatcggaa ccgctcgccg tccctggagc
      961 gatgagcact accgtgaagt tgtcaaagaa acaatccgtg cattgaatcc ttcagatgaa
     1021 gaagcaacta cctttgcaag ccatttttac tatcaatccc atgatgtaaa tgattcaacg
     1081 cattatcaga cattaaaaga attgtctgac cgattagatg gacactatca attaaacggt
     1141 aaccgtgtct attatttggc tatggcacct caattttttg gaacgatcgt ttctcatttg
     1201 aaatcacaaa atattatgac aaaaaatggc ttcaatcgtt tgatcataga aaaaccgttc
     1261 ggttctgatt accagtctgc ttttgaattg aaccagcaaa tcagagaagt attcccagaa
     1321 caagatattt tcaggattga tcattattta ggaaaagaaa tgatccaaaa catctcagct
     1381 atccgttttg ccaataatat ttttgaggct caatggaaca atcgctatat cgacaatatc
     1441 caaattactt ttggcgaaaa cctcggtgta gaagatcgcg ggggctacta cgatcatagt
     1501 ggcgcactta aagacatggt gcaaaatcat attttacagg ttgtagcatt acttgcaatg
     1561 gaaccgccag tagcattttc cgaaaaagaa atccgtacag aaaagatcaa agcattgaaa
     1621 gctatccgca tttataacga agaagaagtg ttagaaaact tcgttcgcgg gcaatatgct
     1681 caaggtgaat tggatggtgt acaattcaag ggctatcgcg aagaagacaa agtggatgct
     1741 caatcagaga ctgaaacatt cgtcgcaggc aaattcacta tcgataactt ccgttggtca
     1801 ggtgttcctt tctatgtacg tacaggcaaa cgtttgactg aaaaagggac tcggatcaac
     1861 atcgtattca aacaagttcc tgttaatgta ttcaaaacat ctgtcgatga accatgtgac
     1921 gatacgacac ttccacctaa tgttctaacg atctatattc agccaactga aggattttct
     1981 ttatccttga atgggaaaga agtagggcaa ggatttgaaa cggaaccaat caaattggaa
     2041 tttagaaata gtgcagaaat ggttgaaaat agcccagaag cttacgaaaa attactatta
     2101 gatgcgttga atggtgatgg aacgaacttc tctcattggg aagaagtcgc tcaatcttgg
     2161 catatcgtgg atgtcattcg aaaagcttgg gaccaaacac aaccggattt tcccaactac
     2221 aaagctggat caatgggacc taaagcagct ttcgaactac ttgaaaaaga cggattcgaa
     2281 tggatctggc aaccagataa ctggtatcgt gaacgtggaa aattaaacga ttgataacaa
     2341 aagggggtgt gacaaagaac atgtcacacc cccttttccc ttttactttt cttcgaatcc
     2401 ttcagctaca gcttcaggat agaagtcttc aacgattttt gcacaacgac cgcatagatg
     2461 aggaagtttt tcatctactc ctacatcttt acgaacttgg cgacagcgat cgcaagtttc
     2521 cccgtctgct ttttccactg taatagcaac atcatcaaat accatagcgt tatctggcac
     2581 ttgttcatct gctgccataa cttcaaagta gtctggtgaa acgatcaata attgtgcaat
     2641 atctgcatcc aaagctttta acatttcacg aacttgttgt tttggataaa cagttagttt
     2701 tgcttccaaa gatttaccaa tcaatttgct gtttcttgct tcttccaatg cttttaagac
     2761 attatcacgg aagtccatga aagcagtcca ggtatccatc aattcttctt ggtttgcaaa
     2821 ctcttcataa ccaggaaact cgcttaactg aacgtactcc tcttcttctt tcaggaatga
     2881 ccagatttct tctgctgtat gcggaatgat aggagtcaat aattttgtca aagctacagc
     2941 tgtttgatag aaaacagttt gcatgcaacg acgttgataa tcatcttctg cttcaatata
     3001 aactacatct ttagcaaaat ccaggtagaa tgacgataga tcaaccgtca agaagttcat
     3061 aactgtacgg taaatatgca tgaagttata tttgtcgtac ccttcttctc ggatttcttt
     3121 gattacttgg ttcaatcgaa cggtcatata tttgtctaca gaacgtaaat cattgtacga
     3181 aacagtatct tttttaggat cgaaatcttc tgtattcgct aataagaaac gcatcgtatt
     3241 tctgatttta cgatatactt ctgccacttg acttaagata tccatagaaa cacgaacatc
     3301 tgcttcataa tctacactag atacccataa gcgaaggata tctgcaccaa attgtttgat
     3361 cactttttct ggtgcaatga tgtttcctaa agatttactc atcttacggc cttcaccatc
     3421 taaagcaaat ccttgagaaa taactgattt gtatggtgct acaccattga tagccacact
     3481 agtcgtgata cttgagttga accagccacg atattggtct gatccttcta aatacatatc
     3541 tgctgggaat gataattctg gtcgctgacg taaaacagct tcatgagaag aaccagaatc
     3601 aaaccagaca tccatgatat ctttttcttt tgtaaattcg ccattaggag aacctgggtg
     3661 ggtaaatcct tcaggaagaa gttctttcgc ttctttttca aaccagataa ttgatccatg
     3721 ttcagcaaat aattttgcca catgttcgat tgtttctggt gtgatgattg cttctccatt
     3781 ttcagcatag aaaatcggaa gtggtactcc ccatgcacgc tgacgggaaa ttacccaatc
     3841 gccgcggtca cggatcatat tatacaaacg tgttttaccc catgggataa cccactctac
     3901 tttttctact tcatccaaaa tattctgacg gaatttatcg atagatgcaa accattgtgg
     3961 agttgcccga tagatcacag gctttttcgt ccgccaatcg tgaggataac tatgagtaaa
     4021 gaaatctagc ttcagcaaag ctcctttttc ttttaataga tcagtgatca taggatttgc
     4081 tttgtcataa aagatacctt caaatccagg tgcttcttct gtaaacaatc cttttgagtc
     4141 tacaggtgac actacagata gtttatattt gctaccagcg atatagtcat cttccccatg
     4201 tcctggagca gtatggacta atccagtacc agcgtctaaa gtaacatgat cgcctaaaat
     4261 cacaagtgat tcacgttcat agaatggatg acttgcagtc atatattcca tttcttgtcc
     4321 agcaaattct tttagaactg ttacattttc ccaaccgatt tctgattgga ctgtttctag
     4381 caaatctttc gctacgacaa acttacggcc atcggcttcc accaatacat acgtaaattt
     4441 tggatttaca gcaatacctt ggtttgctgg caatgtccat ggtgttgtcg tccaaatgac
     4501 aaaagctgta tcttcatcaa gaatatcttt gccgtctttg acattgaaag ctacaaaaat
     4561 agatggagat tttacatctt tatattcaat ttcagcttcc gctaaagaag actcacttga
     4621 cggagaccag taaattggtt tcaatccttt gtaaatatag cctttttcag ccattttacc
     4681 aaatacgcgt acttgtgcag cttcataaga aggatctaat gtaacataag gatgttccca
     4741 atctcctgca actcctaggc gtttgaaatc tgctcgttgc ttatctactt gggaaagtgc
     4801 atattcacga catttttcca agtattctgc catggacatt tctttacgtt tcacgccttt
     4861 attagccaat acttgttcaa tcggcaatcc atgtgtatcc catcctggaa catatggtgc
     4921 acgatagcca gacattgatt ttgaacgaat gataatgtct ttactgattt tattcaatga
     4981 atgtcctaaa tggatattac cattggcata tggaggtcca tcatgaagaa caaagctagg
     5041 ttttccttcg ttcaactctt gtcttttttg gtagattcga ttttcttccc attctttttg
     5101 ccactcgcct tctcggtttg gcaaattacc acgcataggg aattttgttt ttcctaattg
     5161 caaggtttct ttcattttca ttcaaccata cactccttta tttgttttcc ggacacaaaa
     5221 aagcatgttc agccgcaagg gacgaacatg ccgtggtacc acccaaattt agttgcatct
     5281 atctagtgca aactctctgt gaccaataac gaggtcagcc gctgcttctt actctaattt
     5341 cggaaaagca ggtctcaagt agaggatctt tcaccatgca gtgtcttacc gaacttccac
     5401 tctcatcggc tcgctttaag aataacaaag tgcttttctg ttctactcgt tttcattttc
     5461 accaggcacg atcgagatat caatagcctg tgtatcaaat gccgtcatag gtgcttctat
     5521 gactcctgtg tctgagttta catcagtatc attttcattg tcaagctgtt ttgctaaaac
     5581 ttctttgatc acttcatggc tgtcagtcac gtagctggag aatggttgta aaatttcatc
     5641 ccattccgga cttttcactt gttctaattg agactcaagc atcaagctga tacgttgatg
     5701 gaatactcgt gtttttttct taagatcttc agtttctgtc gcaagctgtc ttgctttttc
     5761 tgttgcatct gtcaagattt ttcttgcttt ttcttctgca tcagttgtta attgatgtgc
     5821 acgtttttca gcgttcgcaa ctaactcatc tgctttgttt tgtgcagaag taacgatcac
     5881 ttcggattcc ttgcttgcac ttgtttttac tttatcagcc gtatcttgag ctacgatgat
     5941 tgattggttc aaagcatctt ttaattcatt gaagtactca agtttttctt cagaatgttt
     6001 gactgctttt tctaattctc gatttctttg agtcaattcc tcatagtcac gaacaactaa
     6061 atctaagaaa tcatctactt cgtcttgatt atatccccgc atttttgtcg ggaatgtctt
     6121 attttggata tctaatggag ttaaagccat gagtaaacca cctttttatt ttatttacgt
     6181 aatacaccga acagtaccct gtacttttct tttttcgtct tcccctcaag ttcttggatc
     6241 tggactctgc cataacctct gactgaaata atatctaata gttcaagtac aaaatcaggt
     6301 cttgtatttt ctgtccagtt cacttttact ttaccagctt cgatcagctg cttggaccgc
     6361 tgtctggaaa tattataaat ctcagagatc acactgtcta gtcgcatgga actaactgtt
     6421 cctctttctt gtgtccagct atctttcggc ataatcattt ctgtgtattt gattggttcc
     6481 aagcgtacag caacctttcc aatctttgtt acttgtgcag caacaaaatg atccacctca
     6541 tttgcaataa atacttgcca gcgatcaccg tccgagatga tatcgccaaa gtaagagcgt
     6601 ttgatccccg ttcccactaa agttccaagg attttcccat gacttaggct ggcaaatttg
     6661 ctaggataat ggatttcata caatgctgtt tcaaaatctt cctctacagg ttcgtaataa
     6721 tcggggaaaa tcaaacatct ttttctttct gcctgttcat atccgccata aaacatgaaa
     6781 cgcaaatcac tgctttgtcg aatcagtgtt tctaaaatat aggattgtct tgggtcaaga
     6841 aattcggtca gatagggtgc atattgtcct tgaacctgtt caatccaatc gcctaccgaa
     6901 tcgataaatg tacgttcatc tgcccgaaag tgctggtata catttgcatc caaaattttc
     6961 ccctcctatc tattctgaga ataaagattt tgttgcttca atcaataaac taaatggaca
     7021 gttatccata taacgatctg tgctaaacct tgtacggcta agttcaagat caggattgcc
     7081 cctaaaattg tgaaatccaa gggtccaatc ctcaaaggca gacgatcgaa caaactgata
     7141 tacggttcgc agatcttagc taataatcgt cctagccctg attgataccc gcctggaaac
     7201 caagagagca atgcatatac catcaagata atgctataga aataggctgc ccgttgaagt
     7261 aaatgaagta atagtgcaat agtataaatc gtagttcctc ctcttacaga tcaaacaaat
     7321 tcgcatctgc aaaagattga gcggttgaac tgtcaatctc catcccagtc ggtgtacaaa
     7381 gaaaaatctc atctccaaca cgtttgatat ctccatctag tgcataaact gttcctgtta
     7441 gaaaatcaac gattcttctc gcttgttttt cttctactaa atgaaaattc actaaggttg
     7501 cttctccagc aatgattcgt ttagcaatcg ccatagcttc agaataagct cttggttcca
     7561 ttacagtgat ttttccagca agatttgctt taggttgtgt agaggttctt gaagctgttc
     7621 tttctttcgc tacagttttt gtaggtgatt gatgtagttc aattactttt ttcttttcag
     7681 ccggctgaat actttcatgc gttacaggac gtgaagtcgc cgttttttgt ttttcatgag
     7741 tattcgcagc agatacagaa tgagttgatt gattctgtgt tgtatttttt ttagttggct
     7801 gtacagcctt ttttgttgtt tcaggataat cttggtattc gtactcttcc tcatcagcta
     7861 atccgaaaaa attagcaatt gctcctctgt ttaaaagcgg catttttgtt cctcctttat
     7921 tcgtctttga atagcgctgt tcctacacgg ataaatgttg caccttcttc aatcgcaatt
     7981 tgaaagtctt gactcatccc catacttaat tcactacatg gtgcatgggc ataacctttt
     8041 gcttgaacaa gatcacgcaa ttctttcagc gtaccaaaca ctttatggat ttgctcatca
     8101 gaagcttctt taggcgccat agtcatcaac ccaacaacct tgatttttgt gcaggcagct
     8161 aaagattcca caaacggtaa aagctcatct ggtgaaattc catgttttga ttcctcacca
     8221 gaaacattta cttcaataaa acaggataat tctttctcta accgcttctg gatttcttct
     8281 gctaatctta aactgtccaa cgcatgaaag taatcaattt catttacaat caattttacc
     8341 tttctgcgct gtaaattacc aattaaatgc cactttattt caggaaaatc aaataaatct
     8401 tgtttctttt ctaataattt atctactcgg ttttctgcac aattcataac gccagctcta
     8461 accaattctt cagcttgagc ggattcaaca gattttgtta cagctactaa tgtaacttct
     8521 ttcggatcac gatgaacaag agcacacgaa tcctgaattt cttgcttgat tttctgcaag
     8581 ttgtcagcaa tcatgtgctc ttcctctcct ttatttttta cgacggaaaa acggtggcgt
     8641 atttaattca tcatcgccat gagattttgt ttcttcgcgg ttgaatgtat caaattcttt
     8701 tttttcgata ttgtcaaaat tggaatcatc aactctagga cgaacatttt gttcacgtct
     8761 gatatcccaa tcgccaaaac tgttttcttc ttctgaagaa gttggtttag cttgatccat
     8821 atctaataca gtcttttgag caggtgattg catttgtgct tgtctagctg gtcggctaga
     8881 cttgcgttcc ttttttgatt catcgatacc tgttgcgatg accgtcacac ggatttcatc
     8941 gcccatttct tcattgatag atgtacctag aatgatattt acatcgccag ttgctgcatt
     9001 tgctacgata tctgaagcat cttgtgcttc gaacaatgtc atatccaaac cgcctgtgat
     9061 gttaagaagt acttgttcag ctccatcaat agatgtttca agcaatggag aggagattgc
     9121 ttttttcgtt gcttctacta cgcgatcttc tccactagcc acaccgatcc ccatcaatgc
     9181 tgtaccttgg ttttccatca ctgttttcac gtcagcaaag tcaaggttaa cgtaacctgg
     9241 cgctgtgatc aaatcagaga taccttgtac accttgtcgt aaaacattat ctgcttcacg
     9301 gaaagcttca agcatcggtg tctttttatc tacaacttct aataaacggt tatttgagat
     9361 aattaataat gtatccacat tttctttcaa acgagcgata ccttctgcag caaaacggcc
     9421 acgtttcggt ccttcaaaag tgaatggacg tgtcacgaca ccaacagtca atgcgcccaa
     9481 ttctttcgcg atacctgcaa cgattggtgc agcacctgta ccggttcctc cacccattcc
     9541 tgcagtgatg aaaatcatat ctgcaccgtc taaagcttcg cgtaaggatt gttcactttc
     9601 ttctgccgct ttttgtccaa cttctggctg agaaccagca cctaaaccac gagtatattt
     9661 ggggcctaat tggataactg tttcagcttt tgaatttttt aatgcttgca cgtctgtgtt
     9721 ggctgtaatg aattcaacac ctttaacgtt ttcttcaatc attcggttta cagcatttcc
     9781 accgccacca ccgactccga tgactttgat tactgcgccg tcattgatat tattatcaat
     9841 tgagaattcc atatcttatt cctcccagga tgaattaatc aaaaatattt gtaaagaaac
     9901 ccttgatttt attttttaca ttttctccgg actcttttgg ttccggctca tcgtagattg
     9961 tttcttcagg tgcttcatag ctctcatatg tgtttgttgt ttcttgttca actaccattt
    10021 gacgagctgc tgaggtttca cccgtaacag caatttttgc caattgatac acttcactca
    10081 agtttgctga ataatccacg atacttatta catttgtaaa taccgggttt ctcagcccca
    10141 tgtgatttgg aacatacaat tttacattta cgccgaagat ttcttgtgcc aagtccacaa
    10201 caccaggaag actagcagct ccgcctgtca atacgacgcc acctggcaac tctaatgctt
    10261 cgatttggtc caatgcatct tttgctttgt tgaaaatctg ttccattcga gctgaaataa
    10321 tttctgacaa gtagcgttca tcgactttca ctggttctga ctgaccaatc acatctactg
    10381 gaaattcttc atctggtgat gtccgttctg ggtatgcatc cccgtagttt attttcaacg
    10441 cttctgcatt gttaaatgac gtatttaata caatagagat atctttagtg acaaattcgc
    10501 caccttcttg gtcaagattg gtaaacttca attgcttatc atgcataaca gccgttgttg
    10561 tttggccgcc acccatatca atgacgatcg taccaaaatc tttttctccg tcagaaagaa
    10621 ttgattcagt cagcgctaaa ggagtaatca ccatttcgtt gacgattaat ccggcatttt
    10681 ccacgcattt acgtatgtta tggatgatcg ttttaggtcc tgtaaacaac agaccgtaca
    10741 tttctaatct tacgccgatc attccacgag gatctttgat tccctcgaac ccatcgacag
    10801 taaaatcttg tggcaatatt gacacgattt gacgttcagg aggtattgaa cgaacaaggg
    10861 cagctgaagc cacatttctg acatcttcat cggtgatttc ctttgaatct ccgttaactg
    10921 caatcattcc ctggcaattt tctacttcaa gcatgtttgc tggcaaaccg acacttacgc
    10981 ctttgatctg gatacctgct ttttcttctg cttgtcgtac tgctcgttgt atcgcttgga
    11041 ccgttttatc gatatcaacg ataatgcctc ggttaatccc ttctgatttt gcgtttccta
    11101 ctccaataat attcatttgg ctgtcgatat attcagccac gacaacttta acagatgtcg
    11161 ttccaatatc aaggcctaca tacattcctg tttttgccat gaatgggatt ccctcctact
    11221 tactattcca tatacaagcg aacaactagc gtccgtttta aaatatactt attaatagat
    11281 atattcactg cttccaattc taccataaat tactggtttt tagaaagtac attcttactt
    11341 tttaaagttg ttttatcaat tttcatttaa acttgacgga gttgtacttg gattatcttc
    11401 tatttgactt gtttcacttg aatcatttga atcagatgat ccgtttgtgc tagacgatcc
    11461 aggtgtttgt gctttttgcg tttctgcctc ttcacttgat tcgtttgttt gatccgcatt
    11521 ttcttcactt tcagttgttt cttccgattg gcccgattct tccgtttctt gagtgctacc
    11581 gtaaggatgc gagaagatac caacttccat gtcgatcaca cctttttcat ccatatcttt
    11641 ggctacttgc gaataatatt tcatttggtt cgcaagatta ttgatattta caataacttg
    11701 attgccgtca ttcatattca attggatcag atttttattg cttgctcttg gcgtgtactt
    11761 gatttcagaa attgcttttt gtaattctga tgataactga ttgtattgct ttgttaattc
    11821 tttgattttt gcagagtctt tgaactcttc caagataggg agattttttg taggatttgc
    11881 tactttttca tctaatactg ttccattttc aatcactggg tagtattgat tgttttttgc
    11941 gatcaaagca atctctttat attctgttac atccaaatcg aattcattca tccctttgaa
    12001 atgtatattt gctgtttcga ttcttggctg tgctttttta aggcgatcga tataagtaga
    12061 tcgatgaaaa tactgtcccc aaacattttc tcctaatgac aattttgtat cagagatgat
    12121 ttcttggctg ttgactgtct tattgcctga tactgcaact gcttgtaatt tgctataagg
    12181 agaaacataa tagatcaaaa aaatcagcgg tatacccaat acagtgatga tcaaagctaa
    12241 ccgacgaaat agtactttgt gccgttgact ttttaaattg ggcagccggt tcaaaaaaga
    12301 accgttatat ggtccaccgt ttttcttttg cttgatctct tcaaaaaatt cgattttttt
    12361 ctcggactgg ctttcttctt gctgttcctc ttgaaccgtt ttttcttctt cagaatctga
    12421 aaggggtgta tctaatgtta tgtcttcttt ttttggctct tggtttttca tctcttgttc
    12481 tgccagatat tttcggttag ccttttgcca aggagtcaaa ttgttttcat cagaagacgg
    12541 atgagacaat ttttttggtt cttttttctt actcactaag accaccgcct ttattttttg
    12601 attatttgtt ttactaagtc ataaagacgt tttgaagcat cagggattcc ttgttcttta
    12661 gaagctcggc acatttgctt ttgcaattct tcatcaccca tgatttcgtt gactgtctga
    12721 cttagtgatt cacctgttag ttcattatct gcaatcattt ttgctgctcc tgcgtgaaca
    12781 agactcattg catttttagt ctgatgatca ttcgtaacat atgggctggg aaccaacact
    12841 gccggtaacc ccagagctgt gaattctgcg atcgaagttg caccagcacg ccccaccagc
    12901 agatcactgg aagccatgac ctctgccata tttttgatat aaggctggac actaatattt
    12961 tgtatttcag gatttatttt atttaggatc tcttcataat atctatctcc tgaagcatac
    13021 aaaacttggt aagaagaagg aatatattca cttaaaaaaa ctgatactgc ttgattgatt
    13081 ttaagtgctc cttgactacc gccaaaaatc aagactgttt tcttttctgg atccaaatca
    13141 aatgttttca aaatatctga ttttttagta tctgctactt cttgtgctcg aggattacct
    13201 acaagaactg ctttgttttc aggaaaaaag gaagccgcat ctttaaatga aagagcgatc
    13261 cgatccacat atcggcttaa aaatttattg gtaacacctg gtacactgtt ttgttcatgg
    13321 ataactgttg gaatacccat tttggctgca gcgtacacta ccgctccgga aacatatcct
    13381 ccagtaccga taacgatatc tggttgaaaa tcactgagga ttttttttgc ttgacggata
    13441 ctcttaagaa acaatcggac cgtcttgatg ttatgcatgg aaatttttcg tttaaatcct
    13501 tgaatctcca aggtatggaa aggcattcct gtatcaggga cgattttgtt ttctagacct
    13561 cgttttgctc ccacatacat gaattcagca ttcggttctt gagtctttac ataattgaca
    13621 aaggcaagag ctggataaat atgtccccct gttcctccgc ctgtaaccaa aattttcatt
    13681 ttttatcgct cgcttctact ttttctattt taatcggttc acagcttcca tgaatctgtt
    13741 tcctctagtt tcaaaatttg ggtattgatc ccagctggca ttcgctggtg ataataaaac
    13801 tacatcacca tctgtactgt tttctaatgc taaaggaact gcttgttcta cagaatcggc
    13861 tgttactatt gtctcgatgc ctgctttttt tccagcatcc atcaactttt cttttgtttg
    13921 gccaaatacg accattgctt tgattccttt taatgaagga attaattcat caaatgtatt
    13981 tcctctgtct aatccgccag ccaataacac gaccttagac gtttcaaatc cacttagagc
    14041 cattttagtc gctaaaatat tggttgcttt tgaatcatta taaaattttc tgccttggat
    14101 ttctcctaca tattgcgtac gatgtggtac gccatggaaa aaatgcaacg tttctcgtat
    14161 agcttcattt gatataccat acaattttgc tacagaaata gcagctagtg cattttctac
    14221 attatgctta cctggtacgc caagttcaga tatttccatt attttttctt ttttatagta
    14281 tattgagtaa tcgtcagcat acacaccgtc ttccaacact tcttttgtcg agaaaggcag
    14341 tacgcgtgct tttgttcttt gcgctaattc ttgtagttct gactgattcc agttaaggat
    14401 cagataatct ttttctgtca tgtttttttg aaggttccat ttagctttga catattcttt
    14461 tcttgtacca tgataatcaa tatgtgcttc atagatattg gtaatcaccg ctatatgagg
    14521 gcggaaatct gtgattccca tgagttggaa gctagacaat tccatcacaa ttttatcttc
    14581 tgattttgct tcttgcgcta caccacttgc tggataccca atattacccg ctaaacgtgc
    14641 aattccttga tctgctcctg cattcagtag tagtcctgtc atcgttgttg tcgttgtttt
    14701 tccgttcgtt cctgtaatcc caataattgg gcattccgct acttcgtaag ctagctcaac
    14761 ttccgtaatt accggaatac ccatttcttg ggcttttgct actaaaggat gactgtaggg
    14821 aatccctgga tttttgacca tcaatgaaaa ttcttcatcc aacaattcga ttggatgact
    14881 acctgttatt acttttatcc ctaaagaaag cagctcttgt gcttccggat tttcgtcaaa
    14941 aggttttcca tcattaacgg tgacaagtgc gcccaattca tgtaataatt tggccgcact
    15001 tactccgctt tttgcgagtc ctaagacaag cactttctta ttttcatatg ttgatatttt
    15061 tttcatttcc cgtcatctcc taccaaacga tccataatgt gatcaacgaa gtcacaatgc
    15121 tgatcaacca aaaaactgta tcaatcttcc actccgacca tccgcacatt tcaaagtgat
    15181 gatgaattgg agacatttta aaaattcgtt ttcctgtaag cttaaaggaa gtaacttgaa
    15241 gcatcacact tgctgtttcc ataacataga tcaaaccaat caaaagcaat gtccattctt
    15301 ggtttagcat tatagaaatt gccgctaaaa gtccgcccaa cgctaatgaa ccgacatctc
    15361 ccataaaaat cttggcaggt tttctgttgt agacgaagaa acccagtaaa cctcctaaaa
    15421 cacttaagca aatgattaat acatcatact gatgctgatg ccaagcaatt agaccgtaag
    15481 ctgcaaaaga gatacttcct aagccagcaa ctaatccatc gatgccatct gtcagattta
    15541 ctgcatttga aaatccaaca agccagaaga gagcgaaaat accataaatg attcctaaag
    15601 gtagatctag tccgaagaaa ttcaatacac ctggataacc ttcagaacgg taaacaagat
    15661 aaaagatgat tccccctaga atctgtccaa tcaatttctg cttcgagttc agtcccatgt
    15721 ttcttttctt gaatattttt ataaaatcat caagaaagcc gattactccg tataacgcta
    15781 atacaaaaag caagatgaaa agagtaggag ttagctgttt ttgccaagct ccaacccaaa
    15841 ttcctgtcaa aatagagccg atcagaaaca ctaagccgcc cattgtagga gttccggctt
    15901 tgctattgtg ccactttggt ccctcctcac gaatcgcctg accttgcttt ttcatttgaa
    15961 aataaccaat aaatagcggc attgcggcaa ttgtcattgc acaactgctg acaatgggaa
    16021 tcaatgcttg tgtccattcc atgctctttt ctctcctatt tctcttctta ttcttctaaa
    16081 gtaaaactaa gtttgtcttc agtgattttt tcatatggag caagttcttg tttgacacaa
    16141 taaccatctc catcaaaact aacttcaata ccgaggattt tccccagctt catgatatct
    16201 gcttttgacc atcctgttac gtcaggcatc agcttatcac caccagtata taggatcagt
    16261 ttttctccag agatcaactg atcaccgttg gcagtagatt gtttttgtac ttttttacca
    16321 ttaccgatca ctacaggttg cagtccactt ttttgagcat cagctgctgc aacgtccgct
    16381 tcaagattac gataatcggc tacggatact ttttctgttt ttgtttctgt atctgaatct
    16441 tcttcagttt ctttaaaatc cattgcccgt ttcatcaatg gatttgcgat tttagccaat
    16501 gccattcgat catatgtctt agggtgtttc attgttagat acaagacata gtctggatct
    16561 tcagaaggaa ccatctccac aatcgaatac aggtaggctg tatctcctgt ttgatatccc
    16621 cctgtatcag aagcgatttg ggctgttccg ttttttgccg atacattgta tccaggtaca
    16681 ctatatacac cataagcact accgtagttt tcgctttcga caacatctct catatattca
    16741 cggacttttt ctgttgtttc ttttgaaaaa ggttgcccta gaacttctgt ttgagttgtt
    16801 cgctcttctc cagtttgggg atccaccact ttgctgatat atcgaggttg aatcattgta
    16861 ccgttattcg caatagaagt gaaagctttc atcatttgga aattcgtcac acctaccgct
    16921 tgtccataag cactcattgc tcggtcgaca atatttaatg taggtaaagc accgtttact
    16981 tcatcatcta atccagaatg agtactttgt ccaaatccca gtttttgtaa atagttatac
    17041 catcgtccgc ctaatcgctg ttccagtatg accatcccga cgttacttga ccatgaaaga
    17101 gcttgacgca tggtcagcac acctttttca ccaaagtcat ggtcattgat cgtagcatct
    17161 tctacttgga tttttccaga ttggaaggtt tcattctcgt tgaattctcc ttcttcgata
    17221 gcagctgcag tagtgaaaac tttcatggtt gatcctggtt cataactatc ttgtaccaag
    17281 aaattacgcc agatagcatc ttttccagtc aatccttcca ttgtttcagg attgaaagta
    17341 ggtcgttgtc ccattgccaa gatttctccg gtttttgctt tcatcaggac tgctgtcaat
    17401 tcttctggct gatattcttc atttacttga tccatcagtg tttctaaata actttgtagt
    17461 ctgctgtcta aagtcgtgta gatatcttgt ccgtcgacag ctttttcttc ttctgccact
    17521 gtacctggca gaggattttg aaaattatct ttttgataaa taatcttacc atctttaccg
    17581 ctcaagatat cattgtaagc agactccaaa cctagtttac caactaagcc attctcatct
    17641 ttgtctggaa ctgcgtatcc aataaaatga gaagaaaaga cgccatttgg atacatccga
    17701 gcctgatggt cgacaaaata aagaccagcg acaccttctt ttttcatgtc cgcttcgatg
    17761 ttttgcttgg tttcttggga gatatttttc ccatagctac caaattcaac ttgatacagc
    17821 tctttttttg cgccgtcctc taaaatattc agtgcatctt ttttgtctat agaaagattc
    17881 ttatgcagga tttctgctat tttatcaaaa ttcttttctt caacatacag ttttttatcc
    17941 ccagaggtat atgtttttga gagtatcgct ttaattgaat aagaggaggc atcttctgcg
    18001 agcgccacac cgttacgatc ataaatcgtt cctctttttg cttttactac ttcacttcct
    18061 tggtacaact gttttgtttt ttcagctaat gaggtaccag caacatgacc tccaataacg
    18121 atatacgaga aacggacggc aaataaaaag aacaatccaa tactcgtagc aaataaaatg
    18181 atacctactt ttttgcgatt gttcatcgga tttagatttt tcttttccat aaaccgccga
    18241 attttatttt taagactcat ttacttcact ttccttaaat tgtcgtcatt aatagacaat
    18301 cctttttctt ctgcgatttg tttaatccgt tcagtacgag aaagttcgtt tttttcttgt
    18361 tctaaactcg ttttttcttg ctttttatca ttgatttctg tttgtattga cgtgatttct
    18421 ttttcagctc cgctgatatt tgtgcgcagc ataactgtta aaacacataa agcaacaata
    18481 gcaatcgcca cgcttgccac agcaattttt tccaaagcag aaatctgctt taatcgtttt
    18541 gccggtgatt gtggaagaat gatttcttga ttcgaagaag aatcaggcat ttgttgttcc
    18601 ggctgatcca ccaattcagg taaatcatat tcgtaatctt gcattttctt taattctgcc
    18661 atcattctac tcctctttca ttcttatttt ttctgcaata cgtaactttg cactgcgtga
    18721 tcgattgttt tctgttagct cttcctctga aggaaggatt ggtttacgag taatgacttt
    18781 cagttctggt tggaattcgt caggtatgac aggaagtccc ggtggtagat cttgtaccgt
    18841 actatattct ttaaacatac ttttgacaat tctgtcttcc aatgaatgga atgtgattac
    18901 gctgattctt ccattgactt tcaataaccg gattgcctgt tctaaagagg cctcttcggc
    18961 accgagttcg tcatttactg caatccgcac agcttgaaaa attctttttg caggatgccc
    19021 gccttttctt cttgcgggag ctgggatgac ttgtttaatg atttcgacaa gctcaccagt
    19081 tgtttggatt ggttttgttt ttcgtactcg ttcgatttca cgagcaattt gtttggaaaa
    19141 tttctcctcg ccatagcgga agaaaatctt tactaattca tggtaggaat attcattaat
    19201 tacgtgataa gcggataaag gagctgactg atccatgcgc atatccaacg gtgcatcttg
    19261 atgataacta aatccacgtt ctgcttcatc tagctgagga gaggaaaccc ctagatcata
    19321 caaaatgccg tctaccttat ctacatgctc actcaagcgt tcttctaatt ctctgaagtt
    19381 cgctttgata aatgtgacca taccttgttc gacataagaa gctaaacgca gcttggcgtg
    19441 atcgattgct ttttgatctt ggtcaaacgc atacagatgc cctttagaac ttagttggct
    19501 taataaatat tcactatgtc cggcaccgcc gagtgtacag tctacataaa cgccatccgg
    19561 tttgatgttc aatccatcta ccgtttcttt caacatgact gtatagtgtt gaaatgtttc
    19621 agtcattagt cagcctcttc ctattcttat agtccgaaat caatcatact ttcagcaatt
    19681 tcgtcaaagt tctcttctgc tgctgcagaa aaatcttgcc atcgtgtctc atcccaaatt
    19741 tcaattcggt tagatacacc gatgactacg caaccttttg tcaaagctgc ataatttctt
    19801 aacgtgctgg gtatattgat tcgtccttgt ttatcaagtt cgcattcagt ggcagccgaa
    19861 tagaagaatc gcacaaaagt acgtgcgtct tttttagcca acggcatttc gttcagttta
    19921 gcttccagat tttcccattc gctcatcgga tagccgaaaa gacagccatc caatccgcgt
    19981 gtcagaacaa acttttcgcc aagttcttca cgaagttttg agggcacgat taaacgtcct
    20041 tttgcatcaa tattatgttg gaattcaccc atcaacattg aaagcccccc attcctccac
    20101 taactaaaat tagtctacca caatccccca ctttctacca ccttttctgg gaaatccggg
    20161 aacaactttt tttattcata aacatttttt taaaaatcaa gctgcaaaaa gccttttaaa
    20221 agacttttta cagcttttct atttttttca taggtaagaa agtatgttca caatgatcaa
    20281 gacagcgtac aagacgattg tcaacagaaa aaccaaacgc caagtcatct tgaaataacg
    20341 cggataaata atttcttcat aataatatgc ttggaaaaca gcaatacaaa ttcccattag
    20401 caaaacagaa ataaagaaaa acggtaagat agaaattgtc cctgtatttc tagacaatgc
    20461 atgcataccg ccccacaaaa aaggaatcgc caaatcaggg gcttttattt taaaacgacg
    20521 atttaacgaa aataatttta caagaaattg gcaaccaaac aaaacgatta ccgggtaaat
    20581 ataccaaaac aagataagtg gtgtgaatgt gcccatgaac gtaaactcct tttttatcgt
    20641 tgcttcaagt atactgtata tactttacac aactgtttca ttttatttaa atttatgcag
    20701 ttatattcta tatcttacaa acacattcca tgtattccaa ttccctatcc gttataataa
    20761 aagaaacagg caacaggagg aaaatcatga tcaaatattt tacattagat aatgagaaac
    20821 tgcgtaatac cggaaaggaa actgaccaaa cgatctggta ttgtgtagaa cgtcctaatc
    20881 aagaagagat tcatcagctg acacatcaat ttgaaattcc gtcagattac atcacttcca
    20941 tattggacga tgcagaaaat tcccgtacag aagaattcaa tcaatcaaag ttgacaaagc
    21001 cagcgttatt attgttacaa tatccttttg ctaaaacaag tcctagcggt tattttcaag
    21061 tggatacata cccgctctct attattttga cgcccaaaaa gaagcttatc acaattacga
    21121 atcatgaacc actgttttta aagaaagtct ttagccagac ctttccaaaa agtgatattt
    21181 cgcctaatct caatatcttc tttcaattca tttggcaggt cacactctct tacaacagtt
    21241 atttagctac gcttcaatct caatgcgata ctttggaagc caaacttcaa gtatccactg
    21301 aaaacaaaca actttatcaa atcatggata tccaaaaaag cctcgtttat ttcagagaag
    21361 cgacttctgc taatttagat gcattgaaag aactagcgca aaataaactt ttccaagaaa
    21421 atcatgcttt gaaaaatcat ttacgtgatg tattggtgga aacagagcag gcaatgacta
    21481 cttctcgcat tcaattaaaa ctagtagaac aaatgaatca gactttttca gcaatcgtat
    21541 cgaataatct gaataatatt atgaaaattt taacttcttt aacgattatt ttaactatac
    21601 cgacaatcgt cggcagtatc tatggaatga acattaagtt acctattgct gaaagggatg
    21661 atgcctttat atggctagtt ctattaacat tatttatttg tatcgtaact acctattatt
    21721 taaaaaaagg gaagttttta taaaaaagcc ctcttgtgga aatggaaaaa agattgtaca
    21781 cttgaatcaa ctaattaatg acgaggttga aaacaatgcg tgaaaaaaaa caaacaagta
    21841 cttttgctaa agtaacaaaa tttgtcattt ggacaatgct gattttaacg attggatctg
    21901 ttgtattgac tgctgtaatg agtgtcatgt aaaaataaaa tatagctatc agctgctgaa
    21961 aaggacctga accactgcga ggtggctcag gtcctttttg cgagtttcaa tagttctttt
    22021 gcatgttcga gtgtgagttt tgtaatctca cttccagcca gcatacgtgc aatttcttct
    22081 tctctttctt ttgttttcaa ctctgaaaca gaagtttgcg tacgtccatc aatcactgct
    22141 ttcacaatat aatattgata gtcggcgact gcagcaactt gaggcagatg agtgatgcac
    22201 aaaacttgag agtatttcga tatttgagaa attttatctg cgatggcctg tgcaactctt
    22261 ccgctcacac ctgtatccac ttcatcaaaa ataatacttg tcacaccttg ctcagaagaa
    22321 aaaatagttt tcaaagcaag caacatccga gacagttcgc caccagaagc gactttcacc
    22381 aaaggcttca gtggctctcc tggattggtc gtaatgtaaa attcgatttg gtcaaatcca
    22441 tcatgattca attgtctatt ttcttctttt aagaaacgta cctcaaactc agtgttttcc
    22501 atatacagac ttttcaattc atgcagaatg gatttttcca attcttttgc gattttttta
    22561 cgcgcttcat gaagatctgc ggcttgttgc tgaagtagaa gctctttttg ctctagttcc
    22621 tctttcattt tgtccaattg accttctgaa aaatcagaag aagctagctc ttcggtgatt
    22681 tcgtcatagt aagccaatat tgactcaatg gattcgccgt atttacgttt caactgtcgg
    22741 attaattcta aacgttgcgt aacttcttct aaacgactct catctaactc caataaatca
    22801 atctgacgac tcatatcgcc gattgcatct tgcagcaaat agtaagcact ttggatattt
    22861 tcataaattg cttcatactc cacatctaga tgggcgatcc cttgcagttc tgaaacggcc
    22921 aagccaacac catctacact gttttgttca ttattcgtca gtgctccgta acctgcagct
    22981 aatccatcag caattttttg ataattgcta agtttttctc tttcttcttt taatttctct
    23041 tcttctccga cttgcaaatc agcagcagct atttcttctt gctggaaatg gagcatatct
    23101 attctctgaa cataggattt ttcattttgc tgcacttttc gtaccctttt ttccagctca
    23161 cgataagaga tatattcttg ctgataactc tttttcttct gttggaaagc tacatctcca
    23221 aaacgatcca ataaagcaag atgtgattca ggctggagca gttcctgatg ttcgttttgt
    23281 ccttggatat ctactaaata actgccgatt cttctcagat tagctaatgt gataatatga
    23341 ccattcactc gacaaacatt ttttccagtt aaggacatat cccgtcgaac aatcagattg
    23401 tcctcatctg tttcgatccc taattcaacc atcagttcag agaatccttc ttgttttggt
    23461 agttcaaaca acccttcaag cacacatttt tctgctcctt gacgtatata atcgcttgaa
    23521 cctcttcctc ctgctaacag acctaaagca tcgataataa tggatttacc cgcaccagtc
    23581 tctccggtca gcgcggtcat tccttcgtga aaagaaagcc gcaattccgg aataatcgca
    23641 aagttagtaa tactgatttc ttgtagcatc acattcgctc ctcaacttaa aggtaatgca
    23701 ggaagtcttt cttcaataaa actgcctggt cttcagttcg tgtaatcatc aaaacattat
    23761 cgtcatcatt gataatcgaa aataattctt tcttgtaacg tttatcaatc aaatttgctg
    23821 ctgccgaagc atttcccggc aatgttttca aaataacaaa tttttccatt tggtcaactg
    23881 ccacgaaagc gtcttttaat agtttttcca atttagtatt tacatcttcg tttgtttcag
    23941 ctggtatgct ataacggtag ccgccatctg aagccggtac cttgatcagt ttcagttcct
    24001 ttatatctct ggaaatcgta gcttgagtaa cagatattcc tttgcttttc aggatttcaa
    24061 caaattcttc ctgctttcgg atatcttgct cactcaacaa tcgagtaatc aaacgatgcc
    24121 gatctttttt tctcattacg tcttcgctcc ttagcatatt cttcttaatc aatgatagct
    24181 tatttccttg gtataataaa gaagaatccg catacttctc acttgatttt cacagttaca
    24241 atttatttat ggtcaaactg ttcgtgtgca tttgaaacca cttctgccat attaatagct
    24301 gaattgattg ttccgctttc gggtactttc ctcaagtgag ccaagaactc gatatttcct
    24361 tctccccccg tgatcggaga ataacttaat tccagcacat catatccacc ttgtgccgca
    24421 aatgacaaaa tgtcttctaa aactttttga tgggtctgag ggtcacgaac aattccgttt
    24481 ttccctacag cttctctgcc tgcttcgaat tggggtttga ttaaagcaat cacttctccc
    24541 tcttctttta aaatagcatg taatggaggc agcatcagtt ttagtgaaat aaaagaaaca
    24601 tcgataacag caacttctgg aattcctaag gtaaagtctt cgggttttgc ataacgaaaa
    24661 ttcactcttt ccattacgac gactctagga tcttgtctta ttttccaagc tagctgattg
    24721 tagccaacgt ctaaagcata actcattttt gcgccatttt gcaaagctgc atcagtaaat
    24781 ccgccagtgg atgcaccaat atctaacaat gtttttcctt caacagatag atcaaatgct
    24841 ttgagtgctt tttctaattt taatccccct cgagaaacat aaggaagttt tttacctttg
    24901 actcttaatt cactactcac tggaattttt tctcccggtt tatcaaaccg ctcgtttttt
    24961 tcgttgtaaa tcaaaccagc catcactgaa cgtttggctt gttctcttgt ttcaaataat
    25021 ccttgtttga ccgctaatac atctacgcgt tctttttcca ttctttccct catttctcca
    25081 catcaaattg cttgatcatc tggcgcatca gcccgccatc aaaagaaaaa acgtcctctt
    25141 ctaatttgtc tatgatcttg ttggcggata acagctcaat ctccaacgcc tcacgtgtct
    25201 tttctaggcc taataaacgc gggtaagtat ttttttccat acgttcatct ttaccagctg
    25261 ttttccctaa tgttttcgtt gtaccaatca catcgagtag atcatctctt atctgaaaag
    25321 ctaaacctaa atgttcggct aatcgttgaa gtagcaataa gatttcttca ggttgcttcg
    25381 ctaatatgcc accagccagc aaggcataac gaatcaaatg ccctgtcttt ctttcatgaa
    25441 taaatgctaa ttcttctaaa gaaagctttt tcgattcgcc ctcgatatct gcagcttgcc
    25501 cagcaaccat accttgtgat cccgcacaaa cagctaattg ctgaagcagc agaagcttag
    25561 gagaattacc taagtgtgcc atactgatta gctggaatgc tcctgtaagc aaaccatctc
    25621 cggccaatat agctaatgct tcgccgaata ctttatgatt ggtaggtttt cctctacgaa
    25681 gatcatcatt gtccatcgca ggcaaatcat cgtggatcaa ggaatacgta tgcaccattt
    25741 ctaaagcagc tgctacttga tagacgggaa catcaatagg ctcatcaaag gaagcaacgg
    25801 ccgttaaaag taataaggga cgtattcttt tcccgcctgc tttcactgaa taactcatcg
    25861 catcatagag tcctctatcc gttgtatgct catctaaaaa agacaagatt tctttttcta
    25921 cagcaggtag atgaatagct gaaaagtcag ttaatctcat ctcagctttc ctcgtttccg
    25981 tcaaaatcaa cttcttcatt tgattctgtc atcattttcg tcaaggtctc ttctgcttta
    26041 gctaatgtat cttggcaatg tttgcttaat tccattcctc gtttaaacga atctagagct
    26101 gattctaatg gaacgtctcc ttgttctaac tgcatgacaa ttttttctaa ttcttgcagt
    26161 gactcttcaa aagttggatt ttccatattt ttattctcct ttgtctatct cttgtacttg
    26221 tcctttaacg attccatctt gataatggat cgtcagcaaa tccccttgat gaatctcggt
    26281 gacacttttt actacttgat catttaacgt cgtatagctg tagcctcttc ccatgatttt
    26341 caatggactc aacaaatcaa gagattgaac agcttgagca aaacgctgct gctgttgttt
    26401 catatattgt tggattttct cttctaagcg tttttctaga taagcagttt cttggcgagc
    26461 tgctttaact cgataaagcg gagccacttg ttccaattgg tggcttaatg cgatcgtttg
    26521 tttttctttc gcatgataaa tttgctgtgt agcttgatat aatcgctgtt tcaactggtc
    26581 taatttgatg gtctgacctt catacaatct ttcaggctgc cgaaatacat aggaacgtcg
    26641 agcacgctcg aaccgttctt gtttgcgctg gatctggcgt acaaacgcct gctgcaatct
    26701 agcttgccgt tcttgaatgc gcatcaactc ttctgacaaa acaggaacag ctaattctgc
    26761 agctgctgtt ggagtggcag cccgaacatc tgctactaaa tcagcgatcg tggtatctgt
    26821 ttcatgtcct acagatgaaa tcaccggcgt attagcttga taaatcgccc gagcaacccg
    26881 ctcttcatta aacggccata aatcctcaat cgaaccaccc ccacgaccga tgatcattgt
    26941 atcgaaattg cccatctctt ctactctctg gatattcctg acaacattgt ccgctgcttg
    27001 gtttccttgt acaactgttg ggaacaaaac caattggaca attggatatc ttcttttcac
    27061 cgtcgtgatg atatcgcgga taaccgctcc gcttggactg gtaaggaccg cgattcgctt
    27121 tgggaaacgt ggcagcattt ttttaggccc ttgaaaaagg ccttccttca tcagcttttc
    27181 ttttcgttct tccaattctt gatataaagc acctattcca tcaggctcca tgtgctctac
    27241 atagatttga taagaacctc ccgcttcata taatgaaata cgcccaacga caaggacttt
    27301 cattccttct tttggctgga atcgtaattt ttggaatgct cctttgaaca taatagcaga
    27361 tatttttgca tggtcatctt ttaagctgaa atattgatgg gcattggcac gtaaacggaa
    27421 attcgatatt tcgcctgtta aatatacgcg ttctaaataa ggatcggcat caaattttct
    27481 tttcaaatac ttcgttaatg tagtgacagt taaatattct tgtgccatct attcacctgc
    27541 tccaaaagct tcggcagatt ttacggtttg atacatcagc atcgtgatag tcattggccc
    27601 tacacccttt ggcacaggag tgatccagcc tgcaataggc tccacttcat caaatttcac
    27661 atcaccgatc agcttaccgt tagcatcacg attcatccct acatctatca ctacagcacc
    27721 tggttttacg aattcttttg tgacaaaatg tccacgtcct attgctacga ctaaaatatc
    27781 tgcttcttgt gccagttcag ccagattttc ggttttagaa tgagcaacag taacagttgc
    27841 atctgccatc aagagtagct gagccatcgg tttaccgacg atattgcttc gtccgataac
    27901 tactgctcgt ttacccgccg gatcgataga ataagcttca aacattttca tgatgccgta
    27961 tggagtacaa ggaatcttgt ccggtttacc cgcaaggagt ctgcctaaat tcatcggatg
    28021 aaaaccgtct acgtcttttt cagggcggat agctaacagg atcttttctt catctatatg
    28081 ctttggcaat ggtaattgga ccaatatacc atgaaaacta ggatcttgat tgtatttttc
    28141 aatttctgca agtagttcgt cttcagaaat cgtctcagga taacgctcta ccaatgaatg
    28201 gattccgatt tcttttgcta cacgttcttt atttcttaca tagatttggc tggctggatt
    28261 ttcccctacc aataaaacga ctaatccggg atggatacca ttatctttca atttttggat
    28321 tttttcagca atctctgcct gcattttttc agctaattct tttccgttaa tcaattctgc
    28381 catctaacca ctcccagata ttttttgtgt tttcattcta ccatagaatt ttcccgattt
    28441 ataacaggtt tatgatgatt catagaaaaa agctaggact tacgccccag cttctaattc
    28501 tttcaataca ttggataaaa caccgttgac gaatttacgt gaacggtcat cactaaatgt
    28561 ttttgccaac tcgattgctt catttaaagc aacagccgct ggtacatctg tcacataagt
    28621 catttcaaaa atcgcgatac gcaagatcac caaatccatt tttgagatcc gattgatgtg
    28681 ccaattgttt tttaaatgtt tttcaatcac tttatccaat tcatcttttt ttgcacagac
    28741 accgccaact agcgtatcaa gataaacagg aacaaactct gattcatctt cgttgatcat
    28801 gtcgcggtgg tctaattcga ttgcgttgaa aatcgcatct tcttttgtta ggtctgcatt
    28861 gaagtctaat ggaaataaag cctgcaatgc catttcccga atctcgtgtc ttgataattc
    28921 tttattcatt ctcttcctct tcgtcttcaa aaagttcttc gattgttggt tgttctaatt
    28981 tttcaggaac aacagctact acatggatat tgacttcaga taaatcgata tccgtcatga
    29041 aaaggacttg ctggctgacc cgttcctgca tttccattgc tactttagga actgaaacac
    29101 catattctag ataacagtaa agatctactt tcaagccatc ttcctcgttt gctaagtaaa
    29161 caccttttcc gtgagctgca cgtcctaata attcagtgac attgctggca aaagttccgc
    29221 gcattccgta tacgccttct actttagaag ctgcaatccc gataattact tcgatgactt
    29281 caggagcgat cacgatctct cctaaatctt ggtttgcgtt taaaatcaaa tttttttcat
    29341 ctgccattta tttattcctc cctttgccta agcacgagat acatccgaat tctctatgat
    29401 gcggcatagt gatcacgtgg taagaaaact gccgccgatc agctgcaaac tgctatgaat
    29461 tggagaaaac acccaacttt attatctctt acagcttaaa agttcttcta tagtgtatca
    29521 ttaaatcgag tgattttcta taacaaagtc tgtgaacact gatttttacg cttacttctt
    29581 ctattgatga aactataaga tgatcaattc ttttggtgaa cgagtcaaca cacgatttcc
    29641 atcttctgtg atcaacaagt catcctcaat acgtactcca ccgattcctg gtaagtagat
    29701 ccctggttca tcagtgatca catttcctgg tacaaattgc ttttctgcac gagaagaaac
    29761 gtttggtcct tcgtggatct ctaaaccgat cccatgtcct gtagaatgtc caaatgcttc
    29821 cccgtaacca tgttttgaaa tataatctct agcaactgca tctaattgga caccagtcat
    29881 tcctggtttt gcagcatcaa taactgctaa ttgagcatct aagactattt gataaatttc
    29941 ttttaatttt tccccaggat caccaatagc gaatgtacgt gtcatatcgg aaacgtaccc
    30001 ttcgtaatag caaccaaagt ccaatgtgat caagtcacct tgttcgatga tttttttgct
    30061 tgctacacca tgcggcatag ccgaacgcaa tccgctagca acgatcgtat caaaagaaac
    30121 acctgaagcg ccaagagaac gcatataaaa gtctagttga tttgcgactt caatctcagt
    30181 catgcccggt tggatcattt tcaggatgtg atcatatgcc atatccgcaa tatgacatgc
    30241 tttttcgata atagcgattt cttcttcatc tttcacttct ctgagttctt cgatcatctg
    30301 tgaaacaggt actaattccg catcgatgat ttcttctaaa accgaatatt ctaaaaatga
    30361 gactgttgtt tcctcaaaag ctaatgagtg cagttcttct ttgcgtacta agtttgctac
    30421 ctcatcaaaa ataggtccga catttttaat aatttcaaac ccttgagcct gcgctgccgc
    30481 ctgctcggta taacgaaaat cagtaataaa aaatgctttt tccaaagtaa taacagctaa
    30541 tcctgtcgta cctgtaaagt tcgttaagta acgaagattg tacggactgg taaccaaaaa
    30601 tgaatccaaa ttttcttctt gcattttttt gcgcaatttt tctacacgta gcatcataat
    30661 gaaactccct ctttctttgc acgctttttt ccattatagc aaacttttct tcgtacacga
    30721 cagttaaata aaaatttccg gaaaacttct ttttatttta aataaataaa gccaaaaagg
    30781 agtcacagtc tcgctgcaac tccttttagt ttactatttt gtaaaaactt atgatcgttt
    30841 tccaaagaaa aatgagacaa ctgctaccaa aatcactgcg cctaaaatag atggaataag
    30901 tgccatacct gcagcttttg gtccccattc gccgaaaatc gcttgtccaa tacttgaacc
    30961 gactagtcca gcaatgatat tcgttacaca gcccatcgaa tttcctttac tggtgatcgc
    31021 acctgcaatt gctccgatca cggctccaac aatcaatgtc cataaccaac tcataatata
    31081 acctccttct ttgctaatca attttagcat atgggattta aaggggacaa ataattggtt
    31141 ttgctatttc atattttctt ctgcaaagta aaaaaataaa gaaaacctcc tcttagaagt
    31201 tttctttatt ttttacttgc gtttaaacat actacgaata ccacgtttca ctacatcaaa
    31261 gaaactcaat gattgtacca ttctatcttc atctacatat tctctgatcg cacgaagcac
    31321 ttttttaggt tctttggaag aaaatgtgta tgtaccattt tttttcgttt gaatggcata
    31381 tcgaggaatc cattttccct ttagcatgac tgatgctagt acataatcca cttcttccca
    31441 tggaatttgg atatatttgc gtctatctcg cgcatggtaa aactcaaaac cattattacc
    31501 tatcatgatt tgcccgtaat ctgtcagacc cgtaaacgaa gtagcatcaa ttaccaagtc
    31561 tacttttgta ttgattgatt gaaccatttt ctccctccag atatttgttt atgaacagta
    31621 tactatataa aaaaagctcg ggacaacgcc cgagctatat ttttatggat tataaaagtc
    31681 cgatgacgtg tccaacaaca ccgactacga ataaaccaag gatgataacg attggagaaa
    31741 cctttttctt aagcaaccac atacataaca atgttaatcc taatgcagct aaaccaggaa
    31801 tcaattggtc taagttgtct tgtaatgttg ttaccttttc aggagaaagg gctaagccat
    31861 tattaacttg ttcaaatgca ctcttgattc cttcaccacc tgaaggcaat ttatcccatt
    31921 cgatgtaagc acctttatct aattttacag ttgatacaac tggtaagaat ttgattgata
    31981 cccatctttg tacaagggca gctaatacga acatccctaa aattgaagca ccttttgtta
    32041 cgtcttgtaa caatccgcca gaaaggtcat cagtaatttt agaaccagct ttgtagccaa
    32101 attcttgtgt ataccacatg aatgcccaac gaataatgtt ccaacctaag aagaagatga
    32161 ttggtccaag gatatttcct cccatagcta atgaagcacc tagtgcacct agcattggac
    32221 gtactgtaaa ccagaacact gggtcaccaa caccagctaa aggacccatc atacctactt
    32281 taaccccttg aatcgctaca tcatcaacag gcgcgccatt cgcacgttct tcttccagag
    32341 ccaatgtaac ccctaaaatt ggagaagcaa tgtatgggtg tgtattaaag aattccaagt
    32401 gacgttttaa tgctgcagaa cgttcttctt ttgttttgta taattttttg attgctggaa
    32461 tcatagaaaa tgcccagcca ccgttttgca tacgttcgta gttccatgaa ccttgaatga
    32521 aggtagagcg ccacgcaaca gctaaacgat ctttttttga taatttgatt ttttcttctg
    32581 ccattttatt ttcctccttc aagattaata gtcattcaaa atgtcgccta aagggtcacc
    32641 agagttgctt ccgcctccat tatttgatga accacccatt ttagaaaggt tcaagtaaat
    32701 aagagctaat gcaacaccta aagcacctag agcaatcaat gttaattgag aaattgcagc
    32761 tacaacgaaa ccaataacga agaatggcca tacttctttt gtagccatca tgttgattac
    32821 caaagcgtaa cctacagcta cgaccattcc cccaccgata gccataccat ctgttaacca
    32881 tgctggcatt gattcaagga atgattgcac agtttgtgct gggataaata gcaacgctgc
    32941 tgctgggacc gcgatacgaa ccccttgtaa acatacagca atgatgtgcc acatttcaac
    33001 cttacggatg tttccttctt cagcagccgc atccatcaaa tgaacgattg gaacagcgat
    33061 tgtacgtacg atcattgtta agaacaaccc tgcaacagcc aaaggaacgg caatcgcgat
    33121 cgcagaagga acacctttaa caccttgtcc acctaaaact aaaataattg ctgatgctac
    33181 tgatgctaat gcagcatctg gtgctacagc ggcaccgata tttgcccaac ctaaagcgat
    33241 catctgaagc gtaccgccaa gtacgatacc agcttcgagg ttaccggtaa ctaaaccgat
    33301 caatgtacat gccactagtg gttgatgaaa ttgaaattca tcaagaatac cttccatacc
    33361 agctagaaag gcaactaata cgactaaaat tattgaaata atagacatga taagcctcct
    33421 ataaatttta atattattta ttacgctttt gctaattcag cttttgcttt tttcaaaata
    33481 tcatccatgt tatcgcgtga atcattaggt actttacgta catcgaattt cacacctttt
    33541 tgttcaagct tctcaaacgc ttcaacgtct tcttgtccca tagacaatac tttacttaca
    33601 acgactttac cgaccgaatg cgccattgac ccaacattta attctttgat gtctacgcca
    33661 ccttcaacag ctgtcaatac gtcttcagga ttttcaaata aaagcaatgc tttggtattt
    33721 ccaaaacgag ggtcttttgc tacttcgatc attttgctaa taggaataac atttgctttt
    33781 acacctggag gagcagcttg ttcgattagt ctcttacgca gatcatcctt tgatactgca
    33841 tctgaaacaa cgataatacg gtttggttgc actgcttttg tccaagctgt cgcaacttgt
    33901 ccatgtaaca gacgtgagtc aacacgtgct aatacatatt tgatttttcc gtctccgacc
    33961 acagttcctt ctggaagtgc tcctttaggt tgtgcgtctt caactgctgc tttcggtgct
    34021 tctgccggtt ctaattcttc cggttttact tttacaccgt cttttgctgt ttcaatgatg
    34081 tgtgctgcaa tttcatgagc agattccatt gaaaagcgtg atgcgtaggc ttcaatcaac
    34141 attggtaaat tcaaaccgct gacgattgcc catttatctt tgtgctcttc gaataatgtg
    34201 tttgattgat tgaacggtgt tccgccccat aaatcaacta agaataacac ttcgtcttga
    34261 ttatcaaaag aagcaaccgc ttcttccaat ttggctctca agtcatctgg accttcactt
    34321 ggtttcaaaa tcacggcttt gacgttttct tgttcgccaa agatcattga accggattgt
    34381 aagattcctt cagcaaattg tccatgactt gctaggataa tccctaccat atttatacct
    34441 cctatttact tttgttgtaa caaattcaaa aatattaata attgctaacc attacaacag
    34501 aattatttga ccttttccaa caaccattct tgctacacct ttttgatttt cgctagtagt
    34561 tccatcaaaa ggattttcct gtcagcaggt acttttcgaa tctctaactc cacttcttga
    34621 ctgttcaagt aacgaaagga atcaatatct tgttgattta ctgaaacaaa attggtaatc
    34681 attgatttgc cttcagtaaa actcataccg ccgatattca acgacttcaa ctgtacaccg
    34741 cagcggacaa ccgcttcaac atcttgggga ttggtgaata aaagcatcac ttttgctcgt
    34801 gataataatc cactatgata gatttgaatc attttctgca cggttattac atttgctgtg
    34861 atccccggcg gtgcagcttc ttttagtaga aactttctca atttatcttg agcgactaca
    34921 tcgctgatca caatgatacg ttcaacacct gtttgcttcg accaaactgt tgcgacttgc
    34981 ccgtggatta aacgatcatc tatacgtgcc aatcgaatat ccatctgcaa aactccttct
    35041 tcctcactac ttcacagaaa cccctatcat ttctgtgtga acaaccacct cctagcacac
    35101 actactataa gcaaaaagcg tgccaacttt tttacgatac actaattgaa tttaaaggat
    35161 tcttaaccaa tacacaaaaa cgatacacta taaaagtgta tcgtttttgt gtattcatgg
    35221 cacagtgtat tcttttttat ctaactgatt atggactaga cgtagcagat aatacatttc
    35281 ttctatcggc acttttactt ttatctgatc ttccaacaga acaactgagg ctgccaattg
    35341 gctataaaga ggatcattcg ttgtatttgt caattcgttt tcttccacag tcaatggttc
    35401 attccgaata atacgttcga tcattcctgc tgtgtgcatc actaggttga ttttgaatcc
    35461 atattcttca tcgccgattc ccgtcgtctg agagatttgt gtagaaaatt gccacattgg
    35521 atcgattaac ttactaccat taataaagat gaagttatca gagataaact caacacacgt
    35581 atttttagct gactcttcat ctagggagat gaattcagtt tcctccaatt ctgattccat
    35641 cagcaactga tccaaaatga cttcgatatt ttgatcaata aaacgttcta aaggaataaa
    35701 tggggcttgg atattcaaat cagtaatccc agtagtagct atgatctgat attctttttg
    35761 gataactggc agttcttctt tcacttccac aatcgacaaa gctagaactt ctaattctgt
    35821 ttcttgacgc ttgtttaccg ctcgttcgat caattctttg attctttgtg ctgtaccttc
    35881 gccagatgcg cagatagcca aaacagcttt tttcttatga ataggttttg cttcctgaac
    35941 agattctaca gaagatattt ctgcgtaacc tcgaaaattt ttcaatgatt catgcaacat
    36001 atctagatct gtccctaata ctgagacctt tcgtacagtt tccaaaacta gagaagttgt
    36061 taccatatca acagtacgta ctggaattcc agtgtctctt tgaatttgcg aattaaacga
    36121 cgcaagggac cccatatcta ctaagagtat gaccccgctt ccttcatcta cttcttgtac
    36181 attgcgttca attcggtcca atgctgtttt cggatccata tccaaaggca tgtctactgc
    36241 tcgtacgttc tctgcatcta acaactgttg gacaacttgg accatactgc ttgctgtgct
    36301 gtttccgtga gctgcaacga ctacaccgat tctgccgctt gcttgatttg cccgtaacga
    36361 gacgagtaga acggtcaagt aatagtcttc actttctgga atctccactt gaaaatacgt
    36421 ttcgatataa ctacgcactt ctttcgcaac agcatattca tctggaaaat caaaagccat
    36481 ctcacggatg ttatcattcg tatgccgttc ttctcctaag ttgatttttt tcaaaaaaga
    36541 actgatatgc aagctcatag cataaataaa gttttgctga aactcatatg gtaaagatct
    36601 tttgaccatt acataaatct gattggtcac ttctatgatt ttcggatcta caaattctgc
    36661 taatttgctg tctgcattaa aagaaaaacc atggtcttta tagaaagact tcagatggat
    36721 gttgatatct gtagaaatga aatgattgat tgcttcttga tccaaaccat ccgacttcag
    36781 taaagctgct ttatctccga tgatatcata tagattataa ggtaactcat aggagtccga
    36841 ttggattttc atgatcgtat catttggtgc tacagttatc tttggctcca atattttaga
    36901 aagctctgcc attgcactgc ggttgcttgc taattgaatc aatccgctac gaatcccttc
    36961 tgtcaaatca tcgattgtga tcgagatttc gggtgattgc atatgattta gaaatcctcg
    37021 tgcacatact aactggatat ttgacttcaa ttgtcctata tttccatagg tcacactgcc
    37081 gatcaatgct tttgctacat cttctgtcaa agaaatcttt cgctgcgtgc ggtttgcttc
    37141 gtgggcaatc atgattttta ctaaatcgac tttctcattt gcaggacgtt tttcaaaagc
    37201 cggaagtttg atattgattg ggatacgccg aacaaaagtt tctaatagag aagaacctgg
    37261 gtcttctgtg gtcgcaccta cgatccgtac atttgcttca tgggatttcg ttgtttcccc
    37321 aagacgactg taagttccat gatccataaa gtaaaagatc atttcttgac cttcaggcgg
    37381 caaccggtga atctcatcca aaaacagcat accgccatcc gcttgatcga taatccccat
    37441 tttttcttca tctgcgcctg taaaagcacc ttttgcgtac ccaaataaat gactcatcaa
    37501 aagctcaggg ttattggcat aatcagcaca attgaaaaca atcagttccg tttcctcatc
    37561 tattacatga tgcgcttttg caaaatgata catcgcgtgt gcaaaataag tctttcctga
    37621 tccggtaggt cctgtaatca aacaatttaa tcctcttggc ggatacaaaa tcgcagcttt
    37681 tgcctgttcc actgaatttt tcatgctgcc gttagctcca atgatttttg caaagatatc
    37741 cttagtatct atttggagtg tatttttttc ttcagagacc ggcgtttctt tgtaactgac
    37801 tacatgtttt gtaactggct ttacgtgcgt aacgagtgtt tgatatatgt aacgtactgg
    37861 tcgtccgtct gtctttatca gttttccttc gcgcactagc tgattcagat ctttactgct
    37921 atttgttcgc tgaatcccta acacttcagc aatttcctgt gttgttactc cttgatcata
    37981 ttctgccttt gttaaatgag cggttttttc tttgacatac atataaattc ggtcaatgcg
    38041 ttttgccaat ggtatcgctc cttttctata gactattgta cttaggcttc aaaacataat
    38101 actatgtatt tatttctgtt tcgtcaacta tttacctgat tttgttttgt tgataacacg
    38161 cggatagata gaaatgttca atttaaaaga acgaaaaatc ccgatacgat ttttataatg
    38221 gaaacaagaa aaagaacact gtttaccata taattatttc actgatagca aacaatatag
    38281 cttccatcaa ttgaaaacga tagttatcaa aacatcctga ttccaaattg gcaaaaaaat
    38341 attaagtgta aaaagacaaa gtaaacttcg tagcctccac tacaactttt atttttataa
    38401 acaaaaaagg ctgtgacaaa agtcttgtca caacctcttt aatcataaga ttcaattaag
    38461 cttcttgagc tactggataa acagacactt gttttttgtt acggccttta cgttcgaaac
    38521 gtactacgcc atcaactttt gcaaataaag tgtcgtctcc accgataccc acgtttacac
    38581 ctggatagat ttttgtaccg cgttgacggt aaagaattga tccacctgta actgtttgtc
    38641 catcagcacg tttagcacct agacgttttg attctgagtc acggccgtta gatgtagaac
    38701 cgccaccttt tttgtgggca aataattgta gattcataga taacaacatg gtctgcacct
    38761 cctatttatc attaattgtt ttaatttgga tatattctga gttttcagct tctatcgatt
    38821 gtaatcctaa taaaagattt tctaatagaa tctcagcaat attgttttgt tcttgtgtca
    38881 ttcctgaagt gacttcggta taaagataac cgccttcttc ttcattcatt tcaacaatcg
    38941 gctcaaaacc ggctaatgag gcaatcccgt tgacagtgct gatcgctaac gcagaaacac
    39001 ccgcacaaac gatatcactt ccataaggac cagcatcagc atgcccggtc aaagtgaatg
    39061 aaacgatctg acctgcgtca tttcgcttaa atgttccttt gatcatatat aggccttctt
    39121 tctcaaacgc tattaagcgt tgatcgcgtc gataaccact tttgtatatg gttgacgatg
    39181 accttgttta cggtgtgaat gttttttagg tttgtatttg aaagtaacga ctttcttttg
    39241 tttgccgtgt ttttcaacag taccttcaac agttgcacct gcaacagttg gagcgcctac
    39301 ttttgtagat tctccgccta ctaagataac ttcgtcaaaa acaacttttt ctcctgcttc
    39361 aacgtcaagt ttttcaacat agattgcttg tcccacttca acttttactt gtttaccacc
    39421 agttttaata attgcgtaca tgctataaag cacctccttc tgatatactt agactcgcca
    39481 tccgaagtga cagcatatgc tgtgcttatt acttgttctg agcggttgta gctgtggagt
    39541 ccacaattac aacagtacta gcttaccaga acagcaaccg ttagtcaact aaatttaaaa
    39601 tcaaaaagta aaacaaaaat tcaagcaata cttctgcttt tctatcctca cagttctacc
    39661 aaataaaata gtcgcattgt gtttctttta ttcttataat aaaagaaaaa ggaggagcat
    39721 aaatggaata cccaaaagaa ctgatacaag aagcttcttt aagaatgaac ggccgtcctg
    39781 tagaaggatt tatcgctggg caaggacctc ttcatcctaa actgatgctc gtgggagaag
    39841 ccccagggaa aacagagatt gatacgcatg ttccttttag cggtcaagct ggaaaagaat
    39901 tgatgcaggc actttcttca actggcttaa cacgagaaga ggtgtatatc accagtgctg
    39961 taaggagccg cccgtatcgc gtgactcatc ggatcaataa acggacacaa cagtcagaaa
    40021 ctgtttatcc aaatcggaca cctactcgtt ccgaagtatt tgcgcatgca ccaatattgg
    40081 attacgaact gatgaaggtc cagccaaaat taattgcgac acttggaaac attggtcttc
    40141 aacgtttact tggcaaagaa tatacggtta ccaaaaatca tggtcaactc tatacagggc
    40201 ctgtcttaca attaacagaa caaaaggatg cctacgaatg gtcagaaaaa aactatcgaa
    40261 ttcttccact ttttcatcca gcagctattt tctacaatcg ctcccttgta cctgttatcc
    40321 atcaagactg gcaagtacta gcttcacttt tacagcaata ttaaaaagaa cagacaagac
    40381 cataaaatct tcagtttaca gtcttgtctg ttctttttca ttgttttaat ggctaattgc
    40441 agtatatttc gcatgtaaag ctgtcaacgc atgagcaact gtttgatgtt gatgcgtgaa
    40501 tgtatgttcc cacaagtgag aaagttgttt ttctacttct ggctgcaagg aagtatagat
    40561 aatcgtttgt cctctttgct ctgctttttc ttgaaattca tcaaaaactg cacgtgccgt
    40621 caaatcaata cttggtacgc ctcgcatgga gaaaatgaca ccatcgtgat gatttagttc
    40681 ttccaattta tttttgagtt tttctgaaga cataaaaaac agtggaccac taatatacac
    40741 tactgtccag ttattcagct tttccgtttc tggcagcccc attctttgcc aatcgatcgt
    40801 ttctaatgaa atcgtgatag cagcgctttt gacaacaaaa aatacacagc cgccgatcac
    40861 cccgatcacg atagcaatac ttaaatcaaa gataactgta caaatcatcg taaggataaa
    40921 caatagaact gctgaccaat atttattagt aaatagctcc ttgatcgttt cccattcatt
    40981 catacgccaa gccgtcacaa tcaaaacacc tgcaagtgct ggcattggaa actgtgacat
    41041 cactggcgca aaaacaagca tggagagcag taagacaact gcatgtatca taccagctaa
    41101 tctagtttgt gcaccagatt tgatggccac gcttgtacgg gcgatggccg cagtagcagg
    41161 aatcccgcca aagaaaggaa gcaacagatt tccaattcct tgcgccatta attcttgatt
    41221 gctatctaag ggcttatttg ccattcggcc agccgaagca ccacatagca agctttcaat
    41281 cattcctaat aaagcaatgc taatagctgg aactgccact tgttgcaagg cagaaaagct
    41341 aaaatctccc atattcaaac gattactact gatcaatgtt tgtggaatct tacccacagt
    41401 tgctactggt aaatggaaca atagcataac tgctgttgcc aaaatgatag ccagcagcga
    41461 actaggcatt cgtttcgccc atttttttgg atagataaac atccctaaaa tgactagccc
    41521 tcccatgatc aaagaggctg tgtttatcgg aaatcctatc gtttgataac tacttagttt
    41581 ttcaataacg tttgtacctt ccgagtgaac accaaataaa ttatcgatct gacctaatgc
    41641 aataatgata gcaatacctg aagtaaaccc cgtaattacg ggtgctggga taaaagaagt
    41701 cagtgttcct aatcggaaaa gtcctgctgc aagtaaaaat agacccgcta aaaaagtagc
    41761 aagcaataca ccttgcattc cctttgttgc cgcaatagac atcaagatag ctgccatcgc
    41821 acctgtcgga cctgatattt gataaaaacc gcctgataaa ccgccaataa cgataccggc
    41881 aatgatagcc gtaatcaaac ctgcggccgc atcagctccg cttgataccc caaaagccaa
    41941 ggctaaaggc aatgctacag cagctactgt gatcccagcc aaaagatctt tctgaaatct
    42001 tgaaagatca taacctgaaa attctttttt tagtgaggaa acataatttt tgaacaccta
    42061 tctaactcct ttttcatgaa attttctaaa ataccattca ttagaatatc atatttcatg
    42121 agataaagta atatttttca caaagtttcc tgttagataa attcttattt tttctatatt
    42181 tataagaaaa tagaaagcaa tgccaacaga gctagcccac cttgtttgag taaaatccaa
    42241 cgatcgctag tcaaactgcc atataatgca acaaaaaaaa tagatattaa tagcatactt
    42301 gtgatttctt tagatgcgga agaaagataa gctccataaa gtagtcccac tcctaatagt
    42361 ccattgtaca ctccttggtt cttaaacaat gtttgaacag attttctgct taactcttct
    42421 ttactcattt taaaaaccct acttgtcgtg tcagaatcag ttctcaccgt ttcgatatac
    42481 atgatataaa aaaattcaat tgcaactaga gtcactaaaa ttctagatag tatcgtcata
    42541 tcttcttcct cttttctgat gagttttatt tttttgctcc ttataattgt actcgataag
    42601 gatgtttttt tattttattt gcctttgaaa acaaacaata ttggcacaaa aaacaaagaa
    42661 aaaccgttag aaacctcagt ttctaacggt tttttagcgt cacaggaggg attcgaaccc
    42721 ccgaccgtcc gcttagaagg cggatgctct atccagctga gctactatga caagaatcag
    42781 cggaacatca ataattatag ataattaaat tgcttctgtc aatacgaaat agttatttaa
    42841 ttagcaaata atgaattatt ttggcccaac tactaaatca atcttttaaa acgagacatt
    42901 ctccttcagc tgttctaagg ttatcaattg aaaacaggag ctacattgac ttcatgctac
    42961 tcctgtttat ttagatttcc tgtatccttt aattgactta caaatataga aacttttaca
    43021 tcaagttcga attgagccct cgattcaatc gattatctac aggctgccat aatcatgtat
    43081 cacaactcga ttgtttctga ttcctttgtc attaagatca caccatcacc taatggcaag
    43141 attgtcgatg tcaaatcggg atgatccatc acaacacgaa gaaattcatt taatttacga
    43201 tggatagctc gtttgccacg gggaatctct tcatctggga gcaagatcgt tcctccttgg
    43261 aagatgtcat ctaccatcaa aacgccacct tttcttaaca aacgtaagca ttcaggtaaa
    43321 aattcaatat attttgattt tgcactatcc ataaaaataa agtcatacgg accagacaac
    43381 tccggcaaga tatctgctgc ttgaccttca agcaaagtca ctttatctgt cagtcctaga
    43441 cgttcatagt tttttttagc tttctcgatc atgacatcga aacgatcaat tgtcgtaaca
    43501 tgagcgtttt ctccgattgt cgtggccatg acacttgatg aaaaaccgat agctgctccg
    43561 atctccaaga ttcgttcagg ctgaagctgt ccaagtaaaa atttcaaaaa tacaactgtt
    43621 tcatggggaa taactggtac ttctgctaca tgagcttctt cttccagttt gcctagctca
    43681 cccggtaatt ttttttgctg ggtacgcata aaatccaata gttcttcttt gactacagga
    43741 cgatgcatca tttcattgcg catactactc ctcctcttca cacattatac gaacaactga
    43801 ctaaatctac aagctgcatg agtgttttct cgtgtttcat gttcagaaga gtcgttggat
    43861 ctctggaata catttatgtt tttaacattc ttacaaaaat ttctgtgttc gtctccgctt
    43921 ctttttcaac tctacaaagg tattccatgc tgtgattcct gttaggcaaa aagcaatcgt
    43981 aaagaataac ccctgaatcc atgcaaatgc cgtttttgaa aggactagtc caatatatgg
    44041 aatctgaaag atgggactac cgataatatt tctctttttt actactccag gctcaatata
    44101 agtctttgta tcagcttttg tataaaaatc ttcgtggttg ttttcaacgg ctattacgcg
    44161 acgcgtcgag attttttttc ctgaattttc ataatatgta ataatatctc cgactaaaat
    44221 ctcatttgta tttttcggtc gtacatatat cagatttcct tgtgcataat atggactcat
    44281 ttctttgtcc tcaataatat aaggagtcaa accaaaaatt cggggaacca agacgacgag
    44341 aagaataaga attaaaaata taatcaacgt tatagaactt ataaaagtta tttttttgta
    44401 atcaggtatc gttttcaact tctttcttta ttcaatcctt cttaatcata taataacgat
    44461 aaattttttc aaattatagc tgtaaaaatg tttcccttta ataattatat gtttctaatt
    44521 ctatttcctc atctttatct cattttttat tataaataat tgac
//
LOCUS       DADVXK010000011        38315 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.011, whole genome shotgun sequence.
ACCESSION   DADVXK010000011 DADVXK010000000
VERSION     DADVXK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.011"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..616
                     /locus_tag="KB909_000603"
     CDS             <1..616
                     /locus_tag="KB909_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6836661.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="KB909_000604"
     CDS             613..1386
                     /locus_tag="KB909_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6836662.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="KB909_000605"
     CDS             1383..1781
                     /locus_tag="KB909_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBB6836663.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="KB909_000606"
     CDS             1966..2637
                     /locus_tag="KB909_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836664.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="KB909_000607"
     CDS             2696..3136
                     /locus_tag="KB909_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836665.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="KB909_000608"
     CDS             3148..3816
                     /locus_tag="KB909_000608"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6836666.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="KB909_000609"
     CDS             3880..4503
                     /locus_tag="KB909_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6836667.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="KB909_000610"
     CDS             4559..4945
                     /locus_tag="KB909_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBB6836668.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="KB909_000611"
     CDS             5158..6549
                     /locus_tag="KB909_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBB6836669.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="KB909_000612"
     CDS             7160..7528
                     /locus_tag="KB909_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBB6836670.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="KB909_000613"
     CDS             7708..8649
                     /locus_tag="KB909_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBB6836671.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="KB909_000614"
     CDS             8718..9449
                     /locus_tag="KB909_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBB6836672.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="KB909_000615"
     CDS             9593..11773
                     /locus_tag="KB909_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBB6836673.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="KB909_000616"
     CDS             11793..12275
                     /locus_tag="KB909_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBB6836674.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="KB909_000617"
     CDS             12291..13052
                     /locus_tag="KB909_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6836675.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="KB909_000618"
     CDS             13183..14517
                     /locus_tag="KB909_000618"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBB6836676.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="KB909_000619"
     CDS             14824..15309
                     /locus_tag="KB909_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBB6836677.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="KB909_000620"
     CDS             15302..15985
                     /locus_tag="KB909_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBB6836678.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="KB909_000621"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="KB909_000621"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBB6836679.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="KB909_000622"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="KB909_000622"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBB6836680.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="KB909_000623"
     CDS             19601..20230
                     /locus_tag="KB909_000623"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBB6836681.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="KB909_000624"
     CDS             20282..20614
                     /locus_tag="KB909_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6836682.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="KB909_000625"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="KB909_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBB6836683.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="KB909_000626"
     CDS             21440..22813
                     /locus_tag="KB909_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6836684.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="KB909_000627"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="KB909_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBB6836685.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="KB909_000628"
     CDS             23868..24308
                     /locus_tag="KB909_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6836686.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="KB909_000629"
     CDS             24452..25153
                     /locus_tag="KB909_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBB6836687.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="KB909_000630"
     CDS             25150..26271
                     /locus_tag="KB909_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBB6836688.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="KB909_000631"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="KB909_000631"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBB6836689.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="KB909_000632"
     CDS             27650..28558
                     /locus_tag="KB909_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBB6836690.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="KB909_000633"
     CDS             28593..28865
                     /locus_tag="KB909_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBB6836691.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="KB909_000634"
     CDS             28876..29922
                     /locus_tag="KB909_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBB6836692.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30173..32782
                     /gene="clpB"
                     /locus_tag="KB909_000635"
     CDS             30173..32782
                     /gene="clpB"
                     /locus_tag="KB909_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBB6836693.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32933..33619)
                     /locus_tag="KB909_000636"
     CDS             complement(32933..33619)
                     /locus_tag="KB909_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836694.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33597..34091)
                     /locus_tag="KB909_000637"
     CDS             complement(33597..34091)
                     /locus_tag="KB909_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6836695.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34111..35331)
                     /locus_tag="KB909_000638"
     CDS             complement(34111..35331)
                     /locus_tag="KB909_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836696.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35478..37313
                     /gene="lepA"
                     /locus_tag="KB909_000639"
     CDS             35478..37313
                     /gene="lepA"
                     /locus_tag="KB909_000639"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBB6836697.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            37509..>38315
                     /locus_tag="KB909_000640"
     CDS             37509..>38315
                     /locus_tag="KB909_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836698.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWS"
BASE COUNT        12800 a         6643 c         8270 g        10602 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatcaaaga aaaacgttat ggataagata attttacgtt tgtttggctc
    30001 tttttttata tacatacaat caattttgtt tttttaagat ttatataagt cgagaaaaaa
    30061 agtcaaaaaa ctatgtgtat attttgacca aaattgacca aagcgatata atagtttttg
    30121 taaagatcaa agaaataagt gatcttacct ttaattagga gggtatacct gtatgaatat
    30181 tgagaaaatg actacgacgc ttcaagaagc gattgctgaa gctcaacaga ttgcggtcac
    30241 tcgaaaacat caagatatcg acattgccca tgtatggaaa atctttttac aatctaatca
    30301 ttttggtcga aatttctata cggatgccgg attggatgtc gaatcttttg aacatgaaat
    30361 tgatcgtcta ctggatgagt atccagttgt ttctggtgga aacgtccaat atggacaaaa
    30421 cctcagccag aatttctttc gattattgaa tgaagcagac caaatacgtg aaagcttcgg
    30481 cgacgagttt ctttcaacgg aagtcgttat tttagcgttg atgaaattaa aaaattatcc
    30541 gttaactgtt tatttgaata aaaacggatt atctgaaaaa gaattgcgta aaaacatcga
    30601 agagatgaga ggaggagaaa gagtgacctc acaaaaccaa gaagaacaat acaaagcatt
    30661 agaaaaatac ggcgttgatt tagtacagca agtcaaaagc ggaaaaatgg atccaatcat
    30721 cggtcgtgat gaagaaatcc gtgatgtcat ccgtattctt tcacgaaaaa caaaaaataa
    30781 tcctgttctg ataggagaac ccggtgtagg gaaaacggca atcgttgaag ggcttgctca
    30841 acgtatcgta cgcaaagatg tgcctgaaaa tttaaaagat aaaacgattt tttcattaga
    30901 tatgggtgca ttgatcgctg gagcaaaatt ccgtggtgaa tttgaagaaa gactaaaagc
    30961 agtcttgaaa gaagtcaaaa aaagtgatgg acgtatcctc ttgttcatcg atgaaatcca
    31021 caatatcgta ggggcaggaa aaacagaagg aagtatggat gccggaaatc tgttgaaacc
    31081 aatgcttgct cgcggtgaat tacatttgat cggtgccaca actttagatg agtaccgtca
    31141 atatatggaa aaagacaaag cgttggaacg tcgctttcaa aaggtattag tcaaagaacc
    31201 aacagtggaa gatacgatca gtattctgcg tggattaaaa gaacgttttg agatccacca
    31261 tggtgttaac atccatgaca acgcattagt agcagcagct actttatctg accgttatat
    31321 tactgatcgg ttcttaccgg acaaagcaat cgatttgatc gatgaagcca gtgcaacgat
    31381 tcgggtagaa atgaactcta tgccaacgga attagatcaa gttactagac gtttgatgca
    31441 gttggaaatc gaagaagctg cactgaaaaa agaatcagat gatgcaagta aaaaacgctt
    31501 gaaaaatttg caagaagaat tagctgaact tcgtgaagaa gcaaatgcga tgaagatgca
    31561 gtgggaaaca gaaaaagaag aagtcaattc tgtttcagca aaacgtgctg aaatcgataa
    31621 agcaaaacac gaattagaag atgcagaaaa taactatgat ttagaacgcg ctgctgtatt
    31681 gcgtcatggt acgatacctc aattagaaaa agaattgaag gaattagaag ctaaagcaaa
    31741 agacagcgag attaagatgg ttcaagagtc cgttaccgaa aatgagattg ctcaagtcgt
    31801 tggcagatta acgggtatcc ccgtaacgaa acttgtagaa ggtgaacgag aaaaactaat
    31861 taaattgaat gaaacacttc ataaacgagt gattggtcaa gatgaagcag ttgatgcggt
    31921 cagtgacgcg gtaattcgtt cacgggctgg attgcaagac ccaaatcgtc ctctaggttc
    31981 tttccttttc ctaggaccaa ctggtgtcgg aaaaaccgaa ttagcgaaag cgttagctga
    32041 gaacttgttt gactcagaag atcatatggt acggatcgat atgagtgaat atatggaaaa
    32101 acatgctgtg tctcgtctag tcggagctcc tccaggctat gtaggttacg aagaaggtgg
    32161 tcaattaacg gaagctgtca gacgaaatcc ttatacaatc gtcttgttgg atgaaatcga
    32221 aaaagcgcat cccgatgtct tcaatatctt gttacaagtc ctagatgacg gacgcttgac
    32281 tgattcaaaa gggcgagtag tagatttcaa aaatacggtt ctgatcatga ccagcaatat
    32341 cggttcacag ttactgctgg aaggcgtgac tgctgatgga acgattccag aagcagtggc
    32401 tgaacaagtc aacacgctat tacgtggaaa cttcaaacca gaattcttga accgaatcga
    32461 cgacacgatt ttatttacac cattgagcct agacaacgtg aaaggaatcg ttgacaaaat
    32521 ggtggcgcaa ttggcacaac gtctggaaca tcaagaaatc ctgctgacaa tcagtgatga
    32581 agccaaaacg tggattgctg aaaatgctta tgaaccagca tatggtgcaa gaccattgaa
    32641 acgatttatc actaaggaag tagaaacacc actagctaaa gaaatcgttg caggacatgt
    32701 tatgcctaaa tcaaaagtaa cgattacttt acttgatgga caacttcatt tcaaaacaga
    32761 agagctagaa gaaatcgtct aatcttccat tgagactata aaagaaaaaa ggggtctgac
    32821 acaactagtg tcagacctcc ttttttcaaa taaacagtgt tccagaagta gtttcttcga
    32881 aaaataagcc gaaatttctt gaagctgccc gcttctgtca caacctcttt tattaggtat
    32941 ttttcacttt ttctaattta taactttcaa agtaacgctc atctttttta ctttgagacc
    33001 atgcaaacaa tcccattaag gcagcaccta tcgtatttgt cagcaagtcg cccatcgtat
    33061 ccatcaatgc tgctcgtccg acaaacagtg tgccatcaga agcagcaaaa cgttgaagat
    33121 tcatgcctaa gaactggtcg cataagaatt cccagaactc ccaaaacacg ccgcaaagtc
    33181 cagcaaacgc aaagccgaat aagaggaaca accaaggact ggtttttgat atctcagcat
    33241 ctttcatcaa gtaaccaatc aatccatagc caagagctgt caggaccatt ggactcaccg
    33301 catgtaagat tttgtcccaa aaagagatga tactgatcaa atgcatccct gtgcctaaaa
    33361 agacagagat gaacaagaaa aaccagtaaa acaaaacgat tgctgctggt attttaagtt
    33421 tgaaaacttt caaaatgact tgtggcatga aaatcaatgc aatccctaat aaagattcca
    33481 cgataaatgt gattccttga gaagtcgaat atttttgtgt gataaattca taaaaattat
    33541 agcagacaac gaatacacca aaagcaagta aagctatttg cacctttttg atttctttaa
    33601 tcactgaaag tccctccatc taaaaatctt tttacttctg aaagcaactc aatttctgaa
    33661 gaaaccactt ttccgttcaa tttgatcaaa cctattgtat ataagttcag gtagtgaaat
    33721 tgattttcag ctgtttcttg tagtgcagcg atttttttcg ggtgggttcc gccttgctgt
    33781 cgagtatcag tatataagcc gatcactggg atgcctttcg cataagccac accgatttcc
    33841 gatgctaccc cggcatcgat cgtcagccca tctagtaaag caatcattaa atcactagcc
    33901 aacacttttt ctgtgtcagc aagagcaatc attcgactgt ctgcataagc agttttgtca
    33961 ttgattgctt cattttcttg aggaagatag atcgaaagct cagaagagag ctctctgatt
    34021 tctttaacta actgttggtt atataacaaa tcacttttag caaacattgg tgcggcaaaa
    34081 taaattttca tctaaacatc atccttttta tcaaaaataa tcgctaaagt aagcttccat
    34141 gtttggaatg atacgctcta gtgacttcag tgtttcttca tctgtttcta accgttcgat
    34201 tcttgccaaa taagaagcac ggcgataatt catcatcaag caagtcaatg tttggatatc
    34261 cagtcgaacg gattttccta taggttcatt taagacacgg acttgtccct gttcatccca
    34321 tgttaaagcg aagacaccat tattccaagg agcgacagga tcttcaatga tgaaatgaaa
    34381 agcatcagct gttccaacaa acggaaaccg ttgaaggaat tcttttacat caacgatccg
    34441 agccataaaa tatggttcga tctgctcttt gatctgacta tcttcaatca aaaatgctaa
    34501 aggctcattt ttataaatat ctccatgtac ccagtagatc atggaaaaat gtgcggaaat
    34561 aaagttccat aagccatttc gagcttcttg atcaagatag aacatttctt ttacgtgaaa
    34621 tatttcttca gctacccagt agaacagaac acctcttggt tcatggttgc tatcgtagta
    34681 gacagcggct gtgcgctcat cttcattttc gaaacgccaa tactcttccc aatgaaaatc
    34741 actgcggaat aaagcaccat ggttttgttg ggcaaatttg tcataaacgg aaaatacgtc
    34801 tggatgatca actggtaatc gctcaaccat accacttact gggatttgtt taggtagctg
    34861 tgtatctctg attttaaagg aaagtttatc agacatgatt tcccatcctt tacgccgata
    34921 gtaggggata ctgtaaggat acaaataaga gatccattgc ttattcttgc gcatattatc
    34981 caatgcaacg ataattagat cttgcatcaa tccatggtta gcatattctg gataagttcc
    35041 aactccagtc acaccaccca ttttataacg tgcaccgtga atattgactt cacaaggata
    35101 gatagcgatt tgagagatca gtttattttc gtggaaccat ccgaacactt tcgatacttc
    35161 caaaatcggt tttttggaac ggataaaagc tcgtttattc tcaaacccgc tttcctcgat
    35221 gtctgcttca gtcacttgga acacatagga aagcaattca ttgaattgat cgatatgttc
    35281 ttgagtgacc ggttttaatt caagattttc tctaaaatct ttttgatcca ttttttcatc
    35341 tccatttatt agcttgataa cagtatagca aaattctaca aaaaaaactt ctatagctga
    35401 ctaattaaaa actctttaaa ttactgcttt tcgttggtat aatggaaagt gctgattata
    35461 tgaaaagagg agacgctatg gatataaaga aaatgaaaga acgccaagag cagattcgta
    35521 atttttcgat catcgctcat atcgaccatg ggaaatctac attggccgat cgtattttag
    35581 aaatgacgca cactgtgacg tctcgcgaaa tgcaagatca gctgttagac tcgatggatt
    35641 tggaacgtga acgtggaatc acgattaaat taaatgctgt agaactcaat tacacagcga
    35701 aaaatggaga aacatatatc tttcacttga ttgacacccc agggcacgtc gacttcacct
    35761 atgaagtctc tcgaagcctt gctgcctgtg agggtgccgt tttagtggtc gatgcagcac
    35821 aaggaatcga agcacaaaca ttggccaatg tttatttagc gttagacaat gatttggaga
    35881 tcctgccagt catcaataaa atcgacctac ccgcagcaga tcccgaacgt gtccgtcaag
    35941 aaatcgaaga cgtaatcgga atcgatgcta gtgaagctgt attagccagt gccaaatcag
    36001 ggattgggat tgaagatatt ctcgagcaga tcgtggaata tgttcctgca ccaagtggag
    36061 acttagatgc accgctaaaa gctttgatct ttgactctat ttatgatagt taccgcggtg
    36121 ttgttctaaa tgtccggatc acggacggta tggtcaaacc cggagacaaa atcaaactga
    36181 tgagtaatgg caaaacattt gatgttacag aggtcggggt cttctcgcca aaagcagttg
    36241 ctagagactt tttgatggtc ggtgatgtcg gttatatcac agcaagtatc aaaactgtcc
    36301 aagatacacg agtaggggat acagtaacgt tagcagacaa tcctgccgct gaagctttac
    36361 caggttaccg aaaaatgaat ccgatggttt attgtggtct ttatccaatt gatacttctc
    36421 gttacaacga tttgcgggaa gctttagaaa aactgcaatt gaatgatgct gctttacaat
    36481 tcgaaccaga aacctctcaa gcattaggtt ttgggttccg ctgtggattc ctcggacttc
    36541 ttcatatgga tgtcgtccaa gaacgcttgg aacgggaatt caatctagaa ttgatcacga
    36601 ctgcaccatc cgttatttac catgttaata aaacggatgg tacgactgct acagtagata
    36661 acccggcaga ttttcctgaa cctgtaacga ttcaggatgt agaagaacca ttcgtcaaag
    36721 cacagatcat ggtcccaaat gattttgtcg gtgcagtaat ggaactttct caacgaaaac
    36781 ggggagaatt cattacgatg gattatttag atgattaccg agtaaatgtc gtctataata
    36841 ttccgctttc tgaaattgtc tttgactttt tcgacaaatt gaaatcaagc acgaaaggct
    36901 atgcctcatt ggattatgaa atgtctggtt atcaaaaaag caagttagtg aagatggaca
    36961 tcttgctgaa tggagaaaaa gtcgatgcat taagctttat cgttcaccga gactttgcct
    37021 atgaacgtgg aaaagcaatc gttgaaaaac tgaaaaaact aatcccacgc caacaatttg
    37081 aggtgccaat ccaagcagct attggacaaa aaatcgttgc ccgttcagac atcaaagcct
    37141 tgcgtaaaaa cgtcttggct aaatgttatg gtggagatgt ttctcgtaaa cgtaaactct
    37201 tagagaaaca aaaagaaggg aagaagcgga tgaaacaaat cggctccgtc gaagttccgc
    37261 aagaagcctt catggccgtt ctgaaaatgg atgagcaaga tagtgtgaaa taacttataa
    37321 tcaatcgaaa aacctattaa ataaaccttt ttgagtagat gcaacactga ggattatctg
    37381 tataaaagat tttaaactgt catttggtta tcacggcgat actaaaatta acaaaattgg
    37441 aatatttttc ttgaagattt ttagctgtca gtatatgatg aaagcatctc ataggaggtg
    37501 cttttttcat ggttgataat tcaagtggaa gggttcttaa atctctaaga aaagagaaaa
    37561 aactatctca aaaaaagtta gctgatttag caggtatttc acaaagtact ttagttaaat
    37621 atgaaaaagg gtcaagaaaa atccctaaag acgtagataa tactctaagc aagattctga
    37681 atatagaaac tctaataaaa gatgaggaag ataagattga gattctcatc ggtaaactaa
    37741 ttgcatacag agatatgaat aagttactta acaaagagtt agctgataat ataggaatta
    37801 gtgaagtatt actcagttat gtgttaaata gaaagagaaa tccgtcaaaa gaaatgcaaa
    37861 aaaaaatcga tatttttcta ttaagtaatg aaaaagaaat tttgaaggag attaatcgtg
    37921 atagtgagat atttagttta tcaaaagacg ataaaattgt tatgggaaaa agaatacgag
    37981 aagtccgaaa gaaccgggaa gagacgcttg aaaaatttgg taaaaacttt accatctata
    38041 caggcaaaaa tgttataagt agatgggaaa aaggtattaa tattccagat attgaaaaac
    38101 taatgaatat tgcctatctt ggtaaggtca ctgttcctta ccttatgtac ggagaagatt
    38161 ataagaatat acttccaaaa gatgaaagag ttagcgattt taaaaagata aattctttta
    38221 gtatgggatt aaggatgagg aaaattagga aagattatta tctagaaagg gaggagtttg
    38281 gaaagctttt ttctccttca atttcaaaat ggtcc
//
LOCUS       DADVXK010000012        38255 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.012, whole genome shotgun sequence.
ACCESSION   DADVXK010000012 DADVXK010000000
VERSION     DADVXK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.012"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            198..518
                     /locus_tag="KB909_000641"
     CDS             198..518
                     /locus_tag="KB909_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6836699.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            672..1577
                     /locus_tag="KB909_000642"
     CDS             672..1577
                     /locus_tag="KB909_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6836700.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1574..2347
                     /locus_tag="KB909_000643"
     CDS             1574..2347
                     /locus_tag="KB909_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6836701.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2528..3952)
                     /locus_tag="KB909_000644"
     CDS             complement(2528..3952)
                     /locus_tag="KB909_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6836702.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4163..4609
                     /gene="nrdI"
                     /locus_tag="KB909_000645"
     CDS             4163..4609
                     /gene="nrdI"
                     /locus_tag="KB909_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6836703.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4674..6656)
                     /locus_tag="KB909_000646"
     CDS             complement(4674..6656)
                     /locus_tag="KB909_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6836704.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6670..7566)
                     /gene="murQ"
                     /locus_tag="KB909_000647"
     CDS             complement(6670..7566)
                     /gene="murQ"
                     /locus_tag="KB909_000647"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6836705.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7569..8630)
                     /locus_tag="KB909_000648"
     CDS             complement(7569..8630)
                     /locus_tag="KB909_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6836706.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8841..9407)
                     /locus_tag="KB909_000649"
     CDS             complement(8841..9407)
                     /locus_tag="KB909_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6836707.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(9435..10937)
                     /gene="eat(A)"
                     /locus_tag="KB909_000650"
     CDS             complement(9435..10937)
                     /gene="eat(A)"
                     /locus_tag="KB909_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6836708.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11195..12316)
                     /locus_tag="KB909_000651"
     CDS             complement(11195..12316)
                     /locus_tag="KB909_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6836709.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12442..13383
                     /locus_tag="KB909_000652"
     CDS             12442..13383
                     /locus_tag="KB909_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6836710.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13533..14429)
                     /locus_tag="KB909_000653"
     CDS             complement(13533..14429)
                     /locus_tag="KB909_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6836711.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14698..16038
                     /locus_tag="KB909_000654"
     CDS             14698..16038
                     /locus_tag="KB909_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6836712.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16256..16699
                     /locus_tag="KB909_000655"
     CDS             16256..16699
                     /locus_tag="KB909_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6836713.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17203..18621)
                     /gene="nhaC"
                     /locus_tag="KB909_000656"
     CDS             complement(17203..18621)
                     /gene="nhaC"
                     /locus_tag="KB909_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6836714.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19024..20247)
                     /locus_tag="KB909_000657"
     CDS             complement(19024..20247)
                     /locus_tag="KB909_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBB6836715.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20278..21117)
                     /locus_tag="KB909_000658"
     CDS             complement(20278..21117)
                     /locus_tag="KB909_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6836716.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21134..21814)
                     /locus_tag="KB909_000659"
     CDS             complement(21134..21814)
                     /locus_tag="KB909_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6836717.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21816..22889)
                     /locus_tag="KB909_000660"
     CDS             complement(21816..22889)
                     /locus_tag="KB909_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6836718.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(22945..23183)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23226..23459)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23536..24207)
                     /locus_tag="KB909_000661"
     CDS             complement(23536..24207)
                     /locus_tag="KB909_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6836719.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24294..26972)
                     /gene="mgtA"
                     /locus_tag="KB909_000662"
     CDS             complement(24294..26972)
                     /gene="mgtA"
                     /locus_tag="KB909_000662"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBB6836720.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            27631..28068
                     /gene="ndk"
                     /locus_tag="KB909_000663"
     CDS             27631..28068
                     /gene="ndk"
                     /locus_tag="KB909_000663"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBB6836721.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28090..28956)
                     /locus_tag="KB909_000664"
     CDS             complement(28090..28956)
                     /locus_tag="KB909_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6836722.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29116..31209)
                     /locus_tag="KB909_000665"
     CDS             complement(29116..31209)
                     /locus_tag="KB909_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6836723.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(31958..32581)
                     /locus_tag="KB909_000666"
     CDS             complement(31958..32581)
                     /locus_tag="KB909_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836724.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32740..34137)
                     /locus_tag="KB909_000667"
     CDS             complement(32740..34137)
                     /locus_tag="KB909_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6836725.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34169..35140)
                     /locus_tag="KB909_000668"
     CDS             complement(34169..35140)
                     /locus_tag="KB909_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6836726.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35514..35939
                     /locus_tag="KB909_000669"
     CDS             35514..35939
                     /locus_tag="KB909_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836727.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(36427..37128)
                     /locus_tag="KB909_000670"
     CDS             complement(36427..37128)
                     /locus_tag="KB909_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6836728.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(37144..37584)
                     /locus_tag="KB909_000671"
     CDS             complement(37144..37584)
                     /locus_tag="KB909_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6836729.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37584..38159)
                     /locus_tag="KB909_000672"
     CDS             complement(37584..38159)
                     /locus_tag="KB909_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBB6836730.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
BASE COUNT        11048 a         7988 c         6676 g        12543 t
ORIGIN      
        1 gatatatccg tcagtgcttg gtacacttta ctaaaaagta tgagattgcc gatatctgga
       61 taggtgtgct atactacaga aaaagatata caatctgcca ccgggtagga taaagaggat
      121 gatcattcca ttaggtcttt gaagggatga ttttcctctt tttgtgtatt tttttatagt
      181 taaggaggaa tgtaagtatg gcatggatgg aattaatcat agcaggaatt ttggaagtat
      241 tctggtcaac gatgatgaaa tggagtgatg gtttttctaa aatcaattat tctttttaca
      301 cagtgattgg catgattgct agtttttact ttttgtcaaa ggcaatcaaa agtttgccga
      361 tgagtctctc ttatcctatc tggacaggga ttggcgcagt tggttcggtc ataattggtg
      421 tggtcttgtt tcatgataag ctgaatcttt ccacttggtt ctttgtgggg atgctactca
      481 tcagtatcat tggcatcaag attactagcg gccactagac acttggaata agtactgatc
      541 agaaaaaata agccttttta tttaatattc aattttttta tgaaaaaata agaaataagt
      601 ccaatgacct agcgacttct ccactcatca ggtgtatgct tgtactatct atagaaaagg
      661 agtgaatatt tttgaaaagt ctttcggtcc aagaattatc caagaacttt ggtcacaaac
      721 aagccctcag cgatgtcagt tttagcttat cccctggcaa aatcgttgga ttagtaggtc
      781 ctaatggcgc tggaaaaaca acgatcatga aagctatttt aggactgatc cattactcag
      841 atggaacaat ctgtattggt gaaaatgaga tttctccctc tagtcataaa gggttggaac
      901 aagtaggagc attgatcgaa tacccgggta tctatccatt cttaacaggc tatgatcatc
      961 tgaagttatt ctctgaaacc aacgatgtat ctgctatcga cactatcgtg aatcagctca
     1021 agatggaaaa gtacattcac aaaaaagcga aatcctactc gttgggaatg aaacaaaaat
     1081 tgggaattgc tcttgcctta ctgaaccatc cgtctatcgt tattttagat gagccgatga
     1141 acggtttgga tccacaagca acaagagatg tgcgaaaaat cattaccgac ttggctactc
     1201 agggcacctc tttcttgatc tccagtcact tactcagcga gcttgaaaaa atggtcgatg
     1261 agctgatcct gatcaatcaa ggaaagatca tcaaacaatg tacaatggct gaattgaacc
     1321 aaacagcgca agatttcatc gttatctcta caacaaatga tctagctgct cgaacgatct
     1381 tgacagaagc tggatatact ttggaagatc ctgataaaat caagctttta aaagaaaacg
     1441 aagaattatt aggaaccgtg atccagctat tgtctgcaca aaatatccat gtgacagacg
     1501 tccagcatct gacgaatgat ttggaatctt ctctattgga aattctggat tcagtaaagg
     1561 gggaagaaga aaaatgacat tgcttgtaaa acaagaatta tttaaattga tcaagaaaaa
     1621 gtcaactgct gttttatctg ttctattagt tgttttgctc ataggaacag cacttctagc
     1681 caaaaaatac acgacgatca ttgatccagt tgaaatgact gctcagcttt ttagtgccac
     1741 atcttggatt gtctttatca tgattgcagc tgcaagcacg atcatttcga tggaagcaca
     1801 atatggtaca ttgaaaaatc tcctttatcg aaagtattct cgaggagaaa tattagtaag
     1861 caaatggatc acattagtta tttattctgt ttatttatac cttttagcta ttattgtcac
     1921 tgtgttgatg aaactgattc ttttcccttc gatttccttc acggagaagg tttctactgg
     1981 tcaaacactg atccaaagct tgttcactta tactttgggt agttatatcg gtttatggct
     2041 gattttaagt ttagtgttga tgattgcttg ctttatcaat agttccggcg catccatctc
     2101 agcaggaatc gtcttttatt ttgcttcgtc aatcatatct ggtatcctta ttgcactcat
     2161 ccaaaaatgg gagtggatca aatggaatcc gatcagtatg ttgaatctgc aaaaccaaat
     2221 tggaaacgaa gagatcatga agcaattgac tcatctttct actaatcaaa tgctattcgg
     2281 taatttagct tacatcgttt tgttcttagc attaggatat ctcgtattta agcgaaaaaa
     2341 tgtatgatga ctcatcaaaa aagaggctgt gaaagagacg ttcagcctta ttgccgattg
     2401 gctgtctctt aaacaccgtt tattctgaaa aaggagctgt gacaacattt gtgtcacagc
     2461 tcctttccta gtatgttttt gaataaacga caggctcaca acctctcttt atacttcttt
     2521 tatacttcta tacgtgaagc atcccagtgg caaataaaac cattgcaatc actccgacca
     2581 tcgtcacacc tataagtaaa atcttatcta agtggatatg ttgtacaggc tcgttttgct
     2641 ccttacgtgc tttgaggtaa aaataaatgc ctggcaagaa aagaacaaga acaagcatta
     2701 cttcattaaa ggctacgact agcatagccc atacttgaaa ggcacttgct aaaagcccta
     2761 ctaaaaattg gacccattct ttccgctgat aagaaagttt catttggtac aatcctaaga
     2821 aaagccacgt gaagaaaata gctgctgtac caagtgtgta agcaaagtta taagcactgt
     2881 cagtgaataa taatgaaagt aaaaagacat tcgtacataa cgtcgtcaat acgatagcat
     2941 aagttggtgc cccatttttg ttgagttttc cccatgcttt aggcaaaagt ccgtcttcag
     3001 ccatgtttcc cattgtttca atcggtaaga tcgtccatga gagccaaaca ccaactaaag
     3061 aaatgatcaa accgccgttg atcacgactg ctccccattt accaaccatc atttcaaaca
     3121 catagcccat agcaggctgc gccttgatcg tttgcagctg attcatcgtc attgtcccat
     3181 atggaagcat ggaaaccaag acgtaaataa taatcaagcc gaatatccct agaatcgttg
     3241 ctttcccaac atctgattgt ttttttgctc gtgaacctac gacagaggct ccttcaatac
     3301 caacaaatac ccaaagcatc accatgatgc aactcaatac ttgactggaa aacgggatcg
     3361 gctgtccatt cgcattcaat ataatgtcgc tagaaaagtt atcaatgaat tgttggatcg
     3421 aaaacgtgct gatagctact acaataaata aaaataatgg cactaattta cagaatgtga
     3481 cgatagcatt gacgaaacta gcattttcga ctccccgatt cactagccat gcatatcccc
     3541 ataaaaagac tgtactcatc acgatcgatg ccagattttg cccaccttca aatactggga
     3601 agaaatatcc taatgcgctc atcaacaatg ttgcaaaagc tacgttgcct aaccagcatg
     3661 tgagccagta accccaaccg ctgataaaac cagcgaaacg gccaaaacct tcttctgcgt
     3721 aactaaagat cccgcctttt aaatctggac gttttttatt gatattattg atcgacaagg
     3781 agagcatcaa cattgctgtt cctacgagta cccaactgaa aatagctggg ccgccagccg
     3841 atccggagat gtccgtcata ataccaaata cgccacctcc aatcgctgaa ccaattacta
     3901 aggcagcaag tggaattaaa ccaattcctt ttttctgttg ctctgtatcc atgtaagcat
     3961 cctccaaaat aaaaccgctt ttatcaaaaa gtataacaaa ccttttttat ttttacttaa
     4021 ttaataaaaa ctttaataga aatataattc taccggcttt tttctcatta tacaagcaaa
     4081 gcgcctagtc cctttccaaa ttacaccacc aaaaaactta aaaaagatgc tatactaaaa
     4141 ggaaagaatt ggaggatgat ccatgaacat tttatatata tcgatttcag gaaatacgcg
     4201 tgcctttgcc aaacatctag cagaatatgc tgaaaaaatg catgcagaag atcctgtcaa
     4261 tcctgaagtt actttaaaag aaatccatga aaatagtgat tttacgaaag aaacagaacc
     4321 attttttact ttcgttccta cttatttaga cggcggaaat ggtttagata acggtgatac
     4381 agaaatcttg accgaaacga tgcgtgaata tctggaacat gaagacaatc ataaactttg
     4441 tcttggtgta gtcggtagcg gaaataaaaa cttcaataat cagtattgtc taacagccaa
     4501 acaatatgca caaacatttg gctttccttt cttggcagat tatgaattac ggggaacacc
     4561 atctgatgtg acacgaattt atcagatttt agcagaaaac aataaataat aaaaaagaag
     4621 aagctgaaaa atagatttca gtttcttctt tcgtttctat tgtttctatc atattaagct
     4681 ttgacatcca tcacaggtgc ttttgctttt gctttacctg ttttttccaa gacaaagttt
     4741 tttacacgat ccatattggt taccaagacg atcatggatg tttctttgcc tgctgctttg
     4801 atcgcttcta agtcagcttc tgctacaagc gtatcaggtg tcacttgctg cccttctgtt
     4861 actttcacat caaatggcgt accgcctaag tcaactgtgt tgattcccat atgaagcaag
     4921 atttctaaac catttggcgt tgtgatccca atagcgtgtt tcgttgggaa gacagagctg
     4981 actaccccag taactggaga atagatatgt ccgttttctg gttctacaaa gtagccttca
     5041 cccatcatct tttgtgcaaa aactggatca cttgctttat ctaaagaaac aactgttccg
     5101 tcagcaactg atgagaggat agtcacactt tcagctgaag tttgaggtac tactttttca
     5161 ggcacttcat ttactgtggc tgtttcagtc gctaattctt ctttttctaa acggtcttta
     5221 ggaataccga agaagaatgt agcaacgaag ccaccagcat aagctgccaa taatccaagg
     5281 atgtagccta accatttacc gtcagagatc aatgggatca aagcggctcc tgaaggtcca
     5341 atagcgatag ccccgacatt tccgatcatt ccgatcactg ccccgccgat acctccaccg
     5401 atacaagcag taataaatgg gcgtcctaga ggtaatgtta ctccgtaaat caatggttcg
     5461 ccgattccta ggatcccgac tggtaaagct cctttgatca tttctgttaa ttctttatct
     5521 tttttgcagc gaatccataa tgccaatgct gcacccactt gtcctgcacc agccatcgca
     5581 agaattggaa gcaatagcgt acgaccagtt tcatcaatca tttgcacatg gattggagtc
     5641 aaaatttgat gcagtccgaa cataaccatc ggcaagaata atgtgcctag aacgaagccg
     5701 gcaaatgctc caccaacgcc aagtacccag ttgatcccac cgaccatgcc atcagaaatg
     5761 aaacctgcta aaggcatgat gaagaaaatt tcaatcagac cgatggcaat caatgaaaga
     5821 gttggtgtaa cgatgatatc taccgcatca ggtactactt tatgcagttt tttctcaacg
     5881 attgacaata gccaaacagc gaagatgaca cctaggatcc caccttgtcc agctgcaaga
     5941 gcttcaccag taaataagtt tttcagtggt gcttccggat tcatccctgt cagcatcaca
     6001 acggccccga taactccacc aagagttggt gttgcaccaa aaacttgtgc agcattgata
     6061 cctgtataga taactaggta gctaaacatc ccgtttttca agatgttcat cacatcgata
     6121 tattgttgcc atgttgctgc atcaagtgtt ccggctgtga ctaagtttgc taaaactgcg
     6181 gcaatccctg ccacgatccc agtaccgaca aatgcaggaa tcattggcac aaagatatta
     6241 gaaatgtctt ttaataccga tttgatttta gatggttttt gtttcgattt ttgtgccgct
     6301 ttcatttctt gtgcccgttc gtttacacgg tcttttccag atgctgatga atttgctgta
     6361 gctgtactta cagaagaaag tttttctcct aatttcacgc ctgccaaatc aaccatttgc
     6421 tgtgctactt tgttcacttt cccaggtccg atgatgactt gaagctgttc atcttctact
     6481 acaccaagca ctcctggaat cgcttttaat tcagagacat ttacaagatc atcattgatg
     6541 atcttcatac gcacacgagt catgcagtgg acaatgcttt ctacattgcc catgccgcct
     6601 gcccctttat aaatttgttt tgccagttct tccaaagtca gttcgttttt tgccatggtc
     6661 ttttccccct cataaggtcc cttttacaaa tccgtttgct tcagctaatt ttgcttgagc
     6721 ttcctcttta tcactatttg tcaaaatcat gacgatagcc agcttaacat tttgatctgc
     6781 ttcttcaaag tacttttcag ctgtttcgta atcagcttct gtcgcttgca tgatgattcg
     6841 ttttgagcgt tcgattagtt tttcatttgt tggtttgaca tcgaccatca agttattgaa
     6901 tactttacct ataccaatca tactgatagt agaaatcata ttcaagataa gtttttgtgc
     6961 tgttcctgac ttcaatcgag tagagcctgt caaaaattct ggacctgcat cgacttcgat
     7021 tgggaaatcc gcgtgtttac tgatttcggc ttgtttattg caagaaatcg ttcctgtgac
     7081 agcaccgatc gattttgcgt aatctaatcc accgatcaca tatggtgtac gaccgctagc
     7141 tgcgatacca ataactatat cattttttgt caaattcagc ttgattagat cttcttgccc
     7201 tagctcataa gaatcttcgg ccccttcgac agctacagtc attgcttctt ctccaccagc
     7261 aattagacct atgaccattt ccggttctac accgaatgtc ggtacgcatt cagcagcatc
     7321 taacacacct agtcttccac ttgttccggc tcccatataa atcagacgtc cacctttttt
     7381 aaaggactca atcgtgttag caatcactgg ttcgatactt gtcagttctt tttcaaccgc
     7441 agcggccact ttctgatctt ctttgttcat tagttgaacg gcttgagaaa tactcatctc
     7501 atctaatcca aaagtttctt ggtttctgcg ttccgttgtt aggttctcta aattgatttt
     7561 gctcattttt atcttccttc ttttcttata aattgatagt tcataccagc tttgatttgg
     7621 ttgatcaatg gtagctcttc tttgataact ttagctacta cattcacttt ttcatccgct
     7681 ggcaaatcat atttggttaa ttggatctca cccatatagc gcaaatactt ttcgttatct
     7741 aaagtaatag accctttcat acgcgtagct gtatttcttg ctgggatagg cggaatctct
     7801 cgaaaacgtg catctacgct tcgtatgaca tctcttgcat cgtcttgccg attcgtatgc
     7861 ttccctaata tatattcgta aaattcttca tctacaggtt ccgtatggag caagactgtc
     7921 tgttcttttt ggaaagaagc aaattgctcc tgaacgtttt ctgacagacc tgcatctccg
     7981 atgtaaacaa tatccgtgtt acttgctaat agatctagag cgcctgcaag aggatggatc
     8041 cctcgatgtt cttccaaagt tggcaatcct tgatatagtg ggcctctcaa ctctgtatct
     8101 cctggtacaa aaccttggac aaggagacct tgaattttga gccattgatt ttttttctga
     8161 taccattctt tgtccagccc tgtttcggga cgtggataat aattatgcca agcttcaatc
     8221 tgtgagaaat cagcttctgc ttctttcaat tcatcgatat ctttaggcgt gatcgtgcta
     8281 gcattcaaac tgattttcaa ttgatgtgac cagtcggcaa tctgctgatt ggaaatatga
     8341 taatccattc ttaaacctgt tacaccaatt gctttcaaag gcgttagatc ttctaatgaa
     8401 aaacccgctc gttccaatgc ctctcctgaa atatcgacca tcaattctag tttattcttt
     8461 ttcgcttcgc ttcctagttc gatcaatcgc ttttgatatg ccgaaacatc atcttctggt
     8521 atatgcatgg aagtgaaaat accgacaaag ccattggatg ccatttggcg gatatactgt
     8581 ttcttctctt ctgacaaaga atcgttcata aatattgaaa agccaaacat attatccctc
     8641 tttttctgta tccgtcttca tttctatgac tagagtatat atctaaagaa acaaaatttc
     8701 aatactttta ttaaaataat taaatttcat ttctaaaggt tgagtttata ttatcaaaag
     8761 aattgtcata acctaaaaaa ggcactgcta agcaaaagca gtgccttgaa atattttatt
     8821 taaataacac aaaaacataa ttactcataa gaaaccaatt ctgtattatc taccatgaat
     8881 gtaaagaacc cctcattagg catcggatga aaataagcat tgatcactct tatcaaggca
     8941 ttatggcaaa ctaacagata gacattttct tcgtcttcga tgcattcttt caataaagga
     9001 acgatccgtg catacacatc taagactgac tccccatttg ggaatcgtac agcgaacgct
     9061 aaacgtgctt tttgaaagtt ctcatctttg cttggcagtc catcataatc cccaaaatcc
     9121 atttctacca atcgttcatc aacggtcagc ggcaagctga gacgatcagc aactgcttgt
     9181 gctgtatctc ttgctcgttg aagaggggaa tggatgattt tcgtgattgg aacaggcaaa
     9241 tctactacct tttctgctag tttctgtgcc tgcatctgtc ctttttcagt cagcggcaca
     9301 tctgcccgtc cgcaaactaa tccttgtgcg ttccaagttg tttctccgtg tctcgttaca
     9361 taaagcatgt gattctctcc ttcgttggca aagttcccct taaccatacc ttgttgttct
     9421 tgagattaca agggttagat tctctcaaga gaaataatct cagtagatac tttatccagg
     9481 aaggtttgat catgttccac tagtaacatg gcaggtttca cgttcaagat cagttgttct
     9541 aattgttctt gattgaagac atccaaataa ttcaatggtt catcccatgt atatagttca
     9601 gctggctgtg ataaagattt agccaattcc acttttttcc gttggcccat actcatctgc
     9661 tcgatcttgt tatgaaaaac atctctttcc atcccaagct ttcggaggtt gttcaaaaat
     9721 gcttggtagt ctacttggtt tttctctgca aattccgcca acgttcctcg attgtcttca
     9781 taattttggc ttgcataact aatgctcaga tgttttggct ggtatttttc tcctataacc
     9841 ttgccgttga atgcccccag aagataatgg ataatggatg actttcctgc accgttagga
     9901 cctgaaatcg ccacccgctg atgaggctcg attgtaaaat gaattggctc gaataacaga
     9961 ttttcatacc ctaattgaag atcttctacg cttaaaagtc gcttatggtg agacgcttgg
    10021 ctattcatcg tcaaagaatc gatatattcg atatctttta atagtttttc tttctcgctg
    10081 atctgggtct ccatccgatt cacgattgct ttggatcgtt tcatcgtccg tgcagcatca
    10141 gcacccactg ctcctttatt cactcgtcta gattcagtat cgatgaatcc gacttgtttc
    10201 tttgttttat ctccttctcg ggaacgagac cattcggctt tttcagctgc tgttttcttt
    10261 agcctactga cttctttttt caatttttca ttttgagcca tttcaaattc atcacgaagt
    10321 tttttctgtt cttcatagat agagaaattc ccttgataaa gttccagttg acttttttcg
    10381 attgctaaaa catggtccac tacttcatcg ataaatcccc ggtcatggct gaccacgatg
    10441 aagccttgtt ttttcttttt caaataagcc gctacttgtt ttctaccaga gatatccaaa
    10501 tgattcgttg gttcatcgat taacgggaaa tgagtgtcat ccacaaataa aagtgccagt
    10561 aggacttttg tcttctctcc ccccgatagt gtgctgaatt ctctccataa gatttcagga
    10621 tctgtttgca tcaattggag ctctctttcg atttcccata tctcaaaatc cgtaatatca
    10681 tttaacacgt aataggttaa acgttcttta tcttttgtct gttgcgggaa ataggcaaat
    10741 tcttgctgat ggattacttg cccttgataa ggtagtttgt tttgtagaat attcagtaaa
    10801 gttgtctttc ctcgaccgtt tcgtccgata agtcctagtt tccattgtgt gtcaaaattt
    10861 agatttgctt gttcaaataa taatgtgcct tggctgtcgt agccgaatgt cagatttttt
    10921 atttcgattt tagacatttt ccatcacctc gtaaaaaaag accagtccta ttttcagaac
    10981 tggctaaaga ggatgcaagg gttggataca cacaaaaaga cccatacatc gaaaaaacca
    11041 agccaatccc gaaaatctgc acactgcttc cttgtctcca caaggtacag tctgaatgca
    11101 gctttcatca atcgacttaa tttttcaatg cacggatccc tcactttgtc ctatatttga
    11161 aattacgata gcataaagaa aatgattttg tcaactactt cgggaggatg gtgaaaaatc
    11221 tgctaagtgt ctgtcctaag atttttgttt tttctaatgt ttgcctgtgt tccattgctt
    11281 cttctaaacc tattggaccc aaatgaatac ttaagacaat tgggagaaaa tcagaaagtc
    11341 cttctagctc ttggtctcta cttccgcaaa tagcgattat tggttttcga tatttttttg
    11401 caagcactgc tacaccgtat ggaacttttc cgtggatcgt ttgctgatcg atccgccctt
    11461 ctcctgtaat gatgacatct gcttgttcga tctttttttc caatccagtg atttggctga
    11521 ctaaatcgaa accagaaacc atcttcgctc ccaacaaaaa aagggctcca ccaataccgc
    11581 ctgctgctcc acttcctgga atatcatcta aatccacctc ccagaaatct tttatttgct
    11641 gagcaatctt tcctgcttgt ttatctaaga aagctagcgt cgtatctatt cctccttttt
    11701 gtcttccaaa ttgccaagca gctccttgtt gacctgtata tggattggta acatctgcag
    11761 cgataatcaa ttttacttta gaaacaagaa cgtttcttcg atcaaaatga agttttttag
    11821 tagataataa aggatttcct tctgtgtacc cttctaaaga agcacccaag gattggagta
    11881 atcctagacc accatcgcta cacccgcttc ctcctaaagt gacaataatt tgttctactt
    11941 cttgaagcag tgcatcttta ataagttctc ctaaggcata actggaagca agtcggatag
    12001 tttgatccgt tggtttatca agtagatcta accccaatgc ttgtgcagat tcgatgactg
    12061 cggtgttttt tccttgccaa gttgtcaata aatagctgat ttttcgctga cggaataaga
    12121 gatccatccc atcaatggta cgccatgttc ccctgagcgc gtaatagatt gcttctgcag
    12181 tattttctcc gccatctgca atcggcacat tgatttttct tcctttacga tcttcccagc
    12241 catttagaac tgcctgattt agttcaaatg aagaagcact tcctttaaat gaatcaattg
    12301 ccgccaaaat atccatctgt atccctcact ttcttcttaa gtaagacact ttttttcatt
    12361 tttttcaaac aaaacaatgc tattttcttc catttttcta tatactaaaa gggaactcat
    12421 tgaataaagg agagaaaaaa catgaaaatc gcaatagctg gggccggagc aatgggcagc
    12481 cgaatcggat tgatgctaca tcaaagcgga aatgaggtcc tcttgatcga tcgttggcct
    12541 gctcacattg aagccattcg tacaaatggg ttgattgctg actttaacgg taaagaagtg
    12601 gtcgcaaaac tgccaatcta ttcaccagaa gaaatcatcg aaagcaacga acacgtggac
    12661 ttgatcgtag cattaacaaa agccaatcaa ttagatgata tgttttgttc gatccaatcc
    12721 attattactg acaatactta tgttttgtgt ttactaaatg gattaggtca tgaagatgta
    12781 ctggaaaaat atgtgccaaa gaaaaatatc ttatttggga tcacgatgtg gacagctggt
    12841 ctagctggtc ccggaaaagt cacattgtta ggtgatggag aaatcgaact agagaacttg
    12901 gaaccagaag gcgaagcatt tacaaaaaaa gttgtagaag tctttcaaga agcaaattta
    12961 aatccgatct atagccataa cgttcgttat tccatttggc gaaaagcttg tgtaaatgga
    13021 acattgaatg gtttatgcac gattttggat tgtaatattg ctgaactagg cgcgcaaaaa
    13081 gcggcagaga gcatggttcg aacaatcgta tctgaatttg cttctatcgc agcaaaagaa
    13141 ggaatcatac tagatcaaga agaagtgtac caacatattg cttctactta tgatcctgac
    13201 aacatcgggt tgcattaccc atctatgtac caagacctga tcaaaaacca tcgtttgact
    13261 gaaatcgact acatcaatgg tgccatttgg cgaaaaggac aaaaatatga tattgctaca
    13321 ccatattgtg cctttttgac ccaattagtc catgcaaaag aaggaatcct tggcgcagaa
    13381 taaaaggctc tctgatgaga atcagctgaa tcagcagctg gttctctttt tttaagccca
    13441 ataaaagatc aaaaagaaaa cacaactctc atgatgccat aagaattgtg cttgtttgtt
    13501 tcagtacata atctcttcaa aatgtaggtt ttttatttgt tttcaacaga ggagaggtca
    13561 tattcgtatt gctcataaat agtggaatcg ttagtgataa atcgttttgc ccaattttct
    13621 gcatcataaa attccaatag ctctgatagg attggcttaa atggtgtatg cagaaattcc
    13681 ggtaattcat ctaaatcacg ttctcgaagc aaaaaaatat tttcaggacg ataaaaatga
    13741 taatgagcaa tcgcttgatt atccgtcact agtttctttt gaaaatacat ggattcaaat
    13801 gtccgcaaag tcactccttg ctgaccctcc cgcaacagtt ccagaatccc gcgcgattcc
    13861 cctgtttttt tcaggtactc ttcataagta agatatccag gttgttcatt ccctcgatgt
    13921 ggaagaatga aatagttggt cgtaacatct ctttttataa attcctgctt atagctttct
    13981 gctcgttctt ttctcccatt attcgttgca ccaaaaaata gatccgtctt tggttcgcta
    14041 gaagaaaaat tcatatgttt cgaataaaat gaactattat gtttcagccc aagttctttt
    14101 gcttccaaaa aatcaaaatg ataaatctca tcgattgccg gttcatcttg tgcctgcttc
    14161 agcatcgcct cgtgttctgc tttgaagtga ttccaaaaaa ataacacaat ttttgcattg
    14221 gtaaatgggc gcacgcgtcg agccatctcc atatcaaatc cataatctaa aaaaacgatc
    14281 agctgataat ttgccaactg ttgtctagct gatttaatga attccgactg tagtaaatct
    14341 tttccggacc aaacatctaa agagcggatg gaaggcaaaa aataaagtga tttatttttt
    14401 gcaactagca gtacgtcatt tttgttcatc ttttccgcct cactttctct gtcacttttt
    14461 cctatgatag cctgtttaaa tagtaaaaag ccagtaaaac gtttcctata tttgtatgaa
    14521 aatttaacat ttgtatgaaa atatgatgaa ataaatcatt cttctattaa aattcgccta
    14581 aaagttttct gaatagttgt aattgtctga aaatttgtta tcattagtca ttgttaaata
    14641 ttgctattta ttcttaatat aaattttgat tgtgaattta aaagaaagag gtcatttatg
    14701 gaagataaaa aattgaaaaa acaacttagc tccagacata tcaccatgtt agctttaggt
    14761 ggagcaatcg gtgcaggtct atttaaagga agtggcgaag cgattgggat cgccggccct
    14821 tctgtattga ttgctttttt gattggtggg ctgattttat atatcgtgat gaaaggtctg
    14881 ggaaaaatcg ttttaagcgg tggcgacacg catcacggat tatctggttt gatacgccct
    14941 tatctaggtg ctcattctgc tgattttact gattgggtct actggtctat gtggattatc
    15001 aatatcatcg ctgaagctgt tgcagctgct tcctttttgc agttgtggtt cccgcacatt
    15061 ccagcctggg tatttgtttt tatgttggct gttttaacta cgatcatcaa tctttattcg
    15121 gtacggttat tcgcagaaac agaatattgg ctggcttttg ctaaaatcag tgtcattatc
    15181 ttactgatca tttttgctac ttatcttgtc ggtcagcaaa tgttgggcac aggcgttttc
    15241 cctacccttc agcaattgac tgaccatggt gggtttactc ctcatggtat gaagggaatc
    15301 atcagttctt tgcttgtagt tatctattct tacggcggtt ctgaactgat tgctatcacg
    15361 gtaagcgaag cagatgatcc taaacgtgcg attcctaaag caatcaaagg tgtcatggga
    15421 agaatcattt ccttttacat cattcctttg tttttgcttt tgattctttt tccttggaat
    15481 actttagcag gcacgaatgt cagtcctttt gtgatggtat ttgaaaaaat gaatatccca
    15541 tttgcagcgg atatcgtcaa ttttgtgatt gtccttgctt tgttctcatc tatcaattcg
    15601 ggtgtgtatg catcttcaag aattttgttc ttccgtttga aggatcgaaa aggttcctct
    15661 agaaaactag ctgttttaaa caagcatcaa gtaccgcaac gtgctgtttt attttgtacc
    15721 agtgttcttt atcttggtgt agctctttct tattttgtcg gtgacaaatt atttggctat
    15781 ctggcaggtt ccctttcgta tacagtatta ttgatctgga tcattatcag tgcggcatcc
    15841 tttgtactgg cactaagaaa aggaacatta tgggataaag gaatcagctt ttttgcatta
    15901 gctgtcttag gattgatttt ccttggtatc ctgttcacga actccattgg ggtaactgta
    15961 ttgactggcc tgctttacct gttcatttat ttcagttatc aaaaaaagaa tgatgcgttc
    16021 gtattgacga atgaatgaaa tcgatagaaa attttatttt atttatgtgg aatagatgga
    16081 gctattgaag aaaggagttg tgacaaaagt cttgttgcaa ctcctttttc cgaataaaca
    16141 gtctcatgac ctcttggtaa acggtgttca aaaaccctct gtgcaaaata attgattgtt
    16201 ctccatgctc atgacatgat agaagaaagg aatgaaaaaa aggagtttgt tttaaatgaa
    16261 aaagtattgg aagtttttgt tgatgatcgg tgtttcaacg gtagttatgt ttggtatgat
    16321 gtacttgaat gtctatgcgc tcgatcatat cttcttcagt cgtacacgag tattcatggc
    16381 gttgatgatg ggtgcagtca tggcagtcat catgctgttg ttcatgtgga aaatgtatga
    16441 aaacaaaaag ataaatgtta tgatcttagc cgctagtctt cttgtttttg ccggttcctt
    16501 gtttatggta cgaagccaaa ctactgtcaa cgacacagct tggatgaagg ccatgattcc
    16561 tcatcattct atcgctatcc tggcaagtaa acgagctgat ttaaaagatc ctgaagtaaa
    16621 aaaattagcg gaagaaatca ttcaggcaca agaagaagag atcgacaaaa tgaaaaaaat
    16681 gatcaaagaa atggaatgac cattatccgt ccaaataaaa aaagaggatg ttccagaagt
    16741 tatcagcttc aagaaataag aagaagctac ttctggaacg ccgtgaataa ggggttgtga
    16801 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagcttc tcctattttt
    16861 cgtttggtta ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg
    16921 taaaatcagc gttctgacct gagtattaga gagacaaatg gaaaaatagt tcctcatatt
    16981 ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta tcgagaggtt
    17041 gtgaaaaagt cgcttagttt cgcgtattaa gaaaaatttt gtgaaatggc tttccacatt
    17101 tttgtataaa tttggcttaa taccgagaaa ctggcttttg aataccgttt attcgtaaaa
    17161 gggattgtga caaaagtctt gtcacaatcc ctttttatgt ttttattgtt ctaattgcgc
    17221 tgtcttgctt actgcttctt gcggtttcac aaattttttt gagattcccc aacctgtgaa
    17281 ggcactgacc atcgaaaaca caggagaaag caaactgaaa aatacgaatg gcaagtaagt
    17341 gagtgtagga ataccaaatg tacttgctac gaaacttccg gcaattcccc aaggcactaa
    17401 gtagttgatt actgttccac catcttctag cgttctacct aatacagttg gatcaaatcc
    17461 tgctttttca taagtttctt taaatgcatt accaggcaga ataacagata ggaattgttc
    17521 accaataaaa atatttactc cgatacttgt catcaatgtt gtaaaaatca aatttggtgt
    17581 gttcgtcatc tttcttgata ctcgttccat cacggttgag atcaagccaa attcgatcaa
    17641 caatccacct aatgacaaag ttagaataat caatgacaca gtaggcatca tactttcgat
    17701 tcctccgcgg ctaagcagtg aatcgatttg ttggtttcca gtatttgaaa caaaccctga
    17761 ttcgatgacc ccagccaact tcgttaagga agtttgtggg ttttgaataa aaatcattcc
    17821 tactgctaca gcgatattca acaaaatcgt taaaattgcc ggcacctttt tccatgcaca
    17881 cagtaacatt aaaaataaag gaatcagtga ccagattgaa atagtaaagt ttgcttctag
    17941 aacatcagtc acttcacgaa tagatgaaag acttgcggct ttacttgtgt gtcctaaaat
    18001 catgaataaa aagaaagaaa caacaaatgc cgggacagtt gaccacatca tatgcttgat
    18061 gtgtttgaac aaatcggcat caacaatagc tgctgctaga tttgttgatt cggataatgg
    18121 agacatctta tctccaaaaa cggcacctga aacaatagct ccaacaacca gcgctggatt
    18181 taagcctagt gttgtcccaa taccgaaaaa tgcaatccca atcgttgaca taacagtaaa
    18241 ggcactccct acagcgctac ctacgattgc acacacaaca aatacagaag ggacaaacca
    18301 ctggacactg atcaatttga acccaatgac cattagagtt ggaatgatcc ctgcttgtat
    18361 ccatacagca atcaatgaac cgactaaaat aaaaataaag attgggatga ttcctggttt
    18421 gatgccattg atgattcctt cgtgcagcca atctgtcggg tatcttttta tcactgcata
    18481 caacatgacc attccgatcg ctgctaagat cgtgatatta ggtgagacct ttaatccgac
    18541 aacgccaatc gcaatgccta aaacaataac cattaataca agtgttgctt ctaaaaaact
    18601 tggtgttcct ttttttccca tgataatctc tcctttttta gttgttctta tgttctaaaa
    18661 aagttaagat atcggattac tccgccgcaa ttcatccgcg attcctcctt tataaaaata
    18721 aaaagacctg ttttaaacta aggacgaatg actccgcggt accaccttaa ttaaaaacag
    18781 atctgttttt cactttcaaa cttttattca aatgtatgga ctttccatgt aattcgtcaa
    18841 ttaggcttga tcggttcaca gcgaccaccg actttctgaa caaaacacct aaccgctact
    18901 gcgtgaaaag ttgacttgta cgaagtttac cttccataag atcatttgtc aatgaaaaag
    18961 aaaatatttt ttcatttttc tgaaaattat ttttataact ttcacacaca agtttatttt
    19021 ttactagaaa gtagcgccct cttgtttttt tcttgctact atttcttgat gttcttgctt
    19081 gattctttct aatagctttg gctctttcaa cagatcaaga gctgtattgg cgagtagttc
    19141 tgctgcaatc gcaatagaag caaggccttt gtcactttta gcagcagctt tgaattcttc
    19201 tgtgtgtccg gcaatatatg tctcagagat tgctaccgta ggctggattg ttggtatgac
    19261 ttggctgaca tttcctacat cagaagaacc gagacttgtt ctttgttccg tttctatttc
    19321 ttcatctgga acacctgctt cttttgcatg ctggaagaat aagtcatcaa aagaaggagt
    19381 aacgatgaca tcatcaactg cattttggaa caatccaaac tcaaaagtcg tgcccgtact
    19441 tatcgcagca cctcgtacga tattttccac tttttcatat actttatcta atgtttgccg
    19501 atttcctgca cgtaaataga aacgtccagc agcgtaatct ggaatgacgt tggcagctac
    19561 tcctccgtct gtaatgatcc catggatatt gacatctttt ggcaattgca agcgtagagc
    19621 gttgattcca ttaaacactt ggatcaatgc ttccaaagca tttactcctt tttcaggtgc
    19681 tgctgctgca tgggaagcga caccgtaaaa tttgatgtcg actggatcat tcgctaaaga
    19741 ttctgtcgtt ttcccataac gaaaagctgg atggacgcat aacgctacat cgacatcctc
    19801 aaaaaaacct tctcgaacaa agctgccttt agctgatccg ttctcgcccc cttcttcccc
    19861 tggggtgcca tatacacgga tttctccacc agtttcatca atgaattgct tcactatgct
    19921 ggcggctaat acggagtaag taccaaacaa attatgcccg catgcatgac caatacctgg
    19981 taaagcatcg aattctgcca aaaaggcaat tgtgggaccg ggtttattgg aaatataacg
    20041 tgcatcaaag gctgttcggt gtccagctac ttctttttct acccaaaacc tttctttttc
    20101 taattgttta atcaacgctg ctgaggaata aaactcatag ttacttactt caggatgttc
    20161 gtggatatct agagcaagtg cttgatattc tggtaaacga tattggatta gatccttcaa
    20221 ttggtttgtt gagattgttg ttgtcataaa aaattcctcc tatgctagtc atttttctta
    20281 ttttctcccg aatgtttccc atgcaggcac gcttgatcct tttgatgttt tctcgattac
    20341 tttgactgtg tcttctgttt gataagcgtc tactattttt tgatacgttt tattgttttc
    20401 atcttctttt cttgcaacga tgatattcac ataaggacgt gcatggtcat ccactggttc
    20461 taagaagatg gcatcagaag caggattaaa tccagcatct acagctacac cgctattgat
    20521 cactgaaatg tctacatctg acaaagcacg tgctgtttgg gaagcatcta attcagaaat
    20581 gtctagattt tttctattct cggtaatatc agaaacagtg ggcgcttgtc cttttgcctt
    20641 atccactttg atcaatccag cagtttgcaa taacagaaga gctctgccgc catttgtaac
    20701 atcattaggg attgctactt ttgctccgtc tttgatatca gctacatcct tcaaagtgtt
    20761 agaataaatt cccagcggtg cattgacagt atttccgatc gatactaaat cagttccgtg
    20821 ttctttattg taattgtcta aaaagaattg atgttggaaa gaattcaaat caatcgatcc
    20881 atctgctaaa gccacatttg gttgattgta atctgtaaat ttcacgtatt ccaaattaat
    20941 gttctccttt ttcaaacggt ctttcacgtt gtcccataca tctgtatctt ctccaataat
    21001 ccctagtttt acgatagttt cttttttgtc agttgtatct gcttttcctt ggctacaccc
    21061 tgccaaccaa ataattgcta caaatgtaat gactacaaaa cgaataattt ttttcatttt
    21121 ttctcctcca ctttcaatgt gtaatttttt taatcagttg attactgata aattgactta
    21181 aaaaaactaa gattagaatc aataatgtag ccacaatcgt tacatctgtt tggaatcgat
    21241 tataccctct cgatatagca agattcccta atccgcctgc acctactgct ccagccatgg
    21301 tagtcagtcc gatcacgttg atgatagtca acgccgagac ccgaatgata ccaggcaaac
    21361 cttctaacaa atacacacgt aaaatgatac cgattggact ggttcccatc gcttctgccg
    21421 cttcgatcac cccaggatca acttctagca gtgcgttctc gatttgacga gcaaaaaacg
    21481 gaacaactcc aaaaatcaat ggcactaaag ctgctttcgc accaatcgtc gttccaacta
    21541 agaaacgagt agtcaatgct aaaagagaaa gcaagataat gaaagggatg gaacgaatga
    21601 tattgatcag cttatcaagt atttcaaata gcagacggtt agctagtaat ccattagggc
    21661 gtgtcactac taacgtcaca cctaagatga ttccaatcat cccgccaatg aatgctgtcc
    21721 aaaaagacat atatagtgtt tgcttcgtcg cttcgacaaa ttcatccgga atcaaataaa
    21781 cattgggcaa atatgtttta aagaaatcag tcattttatc ttcctccttc gatcactttg
    21841 atacgactat ctaaatcgtt tttttgtaaa atatttattt ttacaccaga tttgatcaaa
    21901 taatccaatg cttttttccg ctgtttggtt tctccagcta aagtaacgat caaactccct
    21961 aacggcgttt cttgtaataa ctctacattg ccatataaaa tattcgctgt tacttgatat
    22021 ttgctgtaca gatgagcgat tagaggttcg ttcgtctgat ttccaatata acttaattcc
    22081 accagccatt tattggcgat ctgatcggca aaagcagaat gggcaatgat cgtttctaat
    22141 gcttggtcaa gatgagtagc tgttcgaata aaatctttgg tcaattcttc ttcaggattg
    22201 ctgaagatct ggatgctgct acctttttca acgattcttc catcttccat aaccgctacc
    22261 ttgttgcaga tttctttgac aacttgcatc tcatgagtga tcaggacgat tgttaaacct
    22321 aactggcgat tcaatttttt taacaatgca aggatctgaa gggtcgtttt cggatcaagt
    22381 gcactggttg cttcatcaca taataatacc ttaggttcat tcgccaaagc tcgtgcgatt
    22441 gctactcgtt gtttttgtcc ccccgacagt tgtttaggat aagcagatgc tttttcttcc
    22501 aaaccgacaa gttccagtag ttcattcact ttttgacgac gttcctgttt cgattttcca
    22561 gaatacttta aagaaaaatc aacgttgtca aaaatagttc ggctttccat tagattgaaa
    22621 tgctgaaaga tcataccgat ggcctttctt tcttttcgca attctttggg agagagctga
    22681 ctcagattcg tctgattgac aatgacttct cctgctgttg gtttctgcag caaattcatc
    22741 acacgaacta acgtactttt ccctgcacct gagtaaccga cgattccata aacatcgcct
    22801 ttttcaatcg ttaaatctac agaatctact gcctgtatct ctttttcttt ttgtttgaaa
    22861 catacagaaa catctcgcaa ttcaatcatt aaaattcctc cttatctaaa aaaagcgtcc
    22921 tcaagaaaat gaaaatgtca ttttcttgag gacgcttttt tgcgtgttac cacctcatgt
    22981 tcaagctgtg ttcacacaca actcctcttc aagtacgatc atactctagc aagatatcgg
    23041 tcgcagccgt catcgcctta catctatgct cgggatgaat tgctcgatgg ccattttcca
    23101 atagtcgttc cttgcttctt ctcagctacc gaagctctct gtcaaaggtt cttctatcgt
    23161 acttaccatt tcaatgcaaa taatattcaa aaaaaaagtc cttttactaa cataaactat
    23221 gtcagtaaaa ggacgacgta tcgcggtacc accttttttc ggaagtttcc ttccctcaag
    23281 cccaacatct caaaaagaga gattggcgtt cgttttaacg gtcgaacagt tccgaatttg
    23341 cctacttatc gacaaattat tctccaaggc cattttcagc ttttcttact tgactcttct
    23401 caccagccag agcctctctg caaagtttcc aaacttactt tccttttcaa cgaaatcgat
    23461 attttgttgt tgggattaat ctacatgagg aaaactgaaa agtcaagtac gaaattcaaa
    23521 ttattttttc tatatttatt tttctgtttt tttatttaac atttcaataa cagttcgaag
    23581 atcttttcct tccgcaagaa gtttcaattt ttccttttct tcgacggtat aatttcggac
    23641 aaaactggaa tcaggtatca aaacaacgcc taatcctgct cgtgaagcag ctgttgctcc
    23701 tactaaagaa tcttccactg caaaggctga actagcttct aatcctgttc gttccaaagc
    23761 tgtcagataa ggaatcggtg aaggcttgtt ctccgacact tcgtctccga atgtaaacgt
    23821 gtccaagtaa tcagctaatt taaagtgatc caagatatct gttgctcttt tcgtaacagt
    23881 ggtcgtagca atgcctagtt tcatatgacg ttcttttaag tctgccaata tttcttttgc
    23941 atatggtttt aagtggatgg ctccgcttgt cagctgttga taaaaatatt cttcacgctt
    24001 cgctcggact tcctgtactt tttcagggct acctgctgct ttcactaaaa tatcaaaact
    24061 ttgtttccag ttttttccgc cccaagcgtc aacgatttct tttgggatat ggatatcaaa
    24121 ttgctgaaat ccccaaagcc agccatcacg atacgttttt tctgtgtcaa ctaacaaacc
    24181 atctaaatca aatattgcac ctttcatcta tacattaatc ctttccaaaa caatacacat
    24241 agtttagcac gactggtcca aaaagaacag aagcaaagaa ccagccttct cgtttataag
    24301 agttcttgga atcgacggat atagattttc ttcacagctg tcacaagcgc cagataagcg
    24361 atgactgtag caaataacca taaccagtaa ttgccaggaa gtggcatcaa gcctaattca
    24421 gcaccaaaac ttgtaaaagg aaggacagaa ccgacaataa ttcctaatgt agtgataaca
    24481 aacatggcaa atgttgcgtt gctttggata aatggtactt tcggtgtacg cagtgcatgg
    24541 agcactaagg tttgtgtcca tagtgattcg acaaaccatc ctgcatggaa taatgcgatg
    24601 aaaatcactc gctgtgaact atccaatgta tggaaacttc cgcccactac agcaggacaa
    24661 ataacaaaat acatcaacaa gtaagtagta atatcaaata tcgaacttgt tggaccaaag
    24721 taaaccatga attccccaat actagatgca ttccattttt ttggctcgtc caaatattct
    24781 ttatccatcc gatcccatgg caaggaaatg caggaaacat catagatcag attcaaaaac
    24841 aaaagttgta aaggcagcat tggtaaaaat ggcaggaacg tacttgcaat cagcacggaa
    24901 aacatattgc caaaattaga acttgctgta gccttgatat atttcatgat attcccaaaa
    24961 gtttctcgtc cagaaagaag gcctctttcc aaaatcgtca aatctttttc taaaaggatc
    25021 acgtctgcag attctttcgc aatatccaca gctgtatcta cagaaatacc gatatcagcc
    25081 actttcattg caggagcgtc attgatacca tctcctaaaa atccgacagt atgaccattt
    25141 ttacgtaaag ctgtcgtcaa acgtgctttt tgctgaggat tcaattttac gaatacttca
    25201 tggtcttcag ctacttgtgc taattcatga tcactcattt ccgagatttt ctcaccggta
    25261 accaattcat tgatctctag acctacttga cggcacactg aacgtgtaac taattcgttg
    25321 tccccagtca gaacttttac agctacacca tgttctttca gagctttcaa cgcttgtttc
    25381 gttgtttctt ttggtggatc aaggaaagca agataaccaa tcaaaaccat gtctgactca
    25441 tctttgactg aaaattctcc aacgacgctt ggattggtct tttgtgcgac accaatcact
    25501 cgtaagccat cttcattaag tgactgtact tttgcaagta cggcttcttt tcgttctttt
    25561 gttaatggtg taacagtacc gccaagatca ataaatttag aaatgttcag catttcttca
    25621 atcgcgcctt ttgtgatcat ttgtgtttta ccagctggat cagcaaccac aacactcata
    25681 cgacgacgtt caaaatcaaa aggaatttca tccacttttt gataattgat cttatctgta
    25741 tctaaagttt ctgttgcttc atcaatgata gccacatcta acaaattttt cagccctgtt
    25801 tgatagtagc tatttagata cgcatggcgc aaaacacgat catcttcatt tccttcacaa
    25861 tccatatgat attcaagaat gattttatct tgtgtcaatg tccccgtttt atccgtacat
    25921 aacacatcga ttgcaccaaa gttctggatg gcattcaaat ttttgatcac tgttcctttt
    25981 ttggccatca cacttgctcc tttgaccaaa ttcgtcgtaa cgatcattgg aagcatttca
    26041 ggtgttagac caactgctac agatagtcca aaaagaaaag cttctagcca atcccctttt
    26101 gtaagcccat tgatgacgat aactgctgga gccatcaatg acataaattt gatcagtagc
    26161 atggatgttt tatggatgcc taattcaaag cttgattgaa ttggtttttc agatagcgtt
    26221 tctgctacat gaccaaatag tgtttcattt ccaacagaaa caatgattcc ttccgcactt
    26281 ccactgatga cattacttcc cataaagaca agattttcgt aacttgtttc gctttgctga
    26341 tcgtcttcac atactttcgc atgcttttct actggatagc tttcccctgt caatgctgct
    26401 tgggaaatga ataaatcctt tgcggacaat aaacgcatat ccgctggtat catatcccct
    26461 gctgaaagcc gaacaagatc tccacagacg atttcttcca taggaatctc tgtgtacttt
    26521 ccattacgtt ttacagctgc cgttactttc acaagtgatt tcagtttttc agccgcttga
    26581 ttggaacgta cggactgaat caacgtcatt gtcccgctga cgataaccat agtgaagata
    26641 atggctacac cgaaaagatc tttatctcca ggagctgcta atacatattc cgtgatgaat
    26701 gaaataattc ctaatgcgat caacactaat gtaaatggcg tgatgtatgc tttcaatatt
    26761 tctacaatga atggtgtttt tttgccatat gaaatcgcat tttcaccgta attttctctt
    26821 gaacgttcga tttgttcttc tgtcaatcca tttgctgatg catggaatag ttcaaataat
    26881 tcttgtttcg tttttccagc aaaagctgca tagatttttt gtgtatcttt ctttttttcc
    26941 atctcaatct ctcctttgtg tccaaaagac agctgttctc gctgcttttg gtctttagct
    27001 attcatcgga tcgatagaga aaaaactgaa aggggctgag aacagataga taatagccct
    27061 ggcctttcct ctagatcctt gtttttcgaa tgactgtcat ccatttgttc tcatctcctt
    27121 tactaagtaa ttttaattca tgacttccaa tcatttttcg aatagttatt tttccaatta
    27181 gaccacctcc tttttatttt tcaccgatgg ggatttgcgg caacaaaaaa acctctcgcc
    27241 aaatactcag cgaaaggttt gaaaaagcat attaaaaaaa gcttctcaga tctcatcgtt
    27301 gagttttgac actgtacaac gtaaaaagca gatacctgct tttagctacc ttatgaaaag
    27361 ccttatctcg acaattcctg ttctacccat tggcgtctct cgacgttttt gggcagtagc
    27421 ctatgtttgt ataggagcct cacctaacaa atcttattcg gttttccttc gttaatataa
    27481 caactaaaaa agaggatgtc aaatcaattt tccatgtttt tcatactttt tttaaaatac
    27541 acacgttata ttcctgtctc acgcggtttt atttgtctca ttttccacct cccgctataa
    27601 tagaaatata gtaggaaacg aggtgctgtt atggaaagaa cacttgttat tatcaagcca
    27661 gacggcgtga gacgccattt agtcggaagc atcatccaac gttttgaagc aaagggactg
    27721 gccattgctg aaatgaagtt tgaaactatg actcctgaat tagcaaaaga acattatcag
    27781 cacttgactg agcgcagttt ttttgatgaa ctgatcgatt acatgacttc cggtcctgtc
    27841 gtttatcttg tgctggtcgg cgaggaagtg atcgatatcg tccgtaagat ggttggagca
    27901 acaaaagctg ccgatgctgt tccaggtacg atccgaggag actacgcgct gccggggact
    27961 gaaaacatca ttcacgcttc tgattcccgt gatgctgcgg taaaagagat cgcccgcttt
    28021 ttcccgccat tcgatataaa caaaccgtct gaaaaagcgg cgaagtgata caaattctaa
    28081 actgctggtc tagttgctgg gttcagcaat ggccagcagt tttttctcta aggacctccg
    28141 ttgattcttt cctaacatat attcgagcac tgtgaagaat tcttggtagt ctttcgtctt
    28201 ttcttcccct aaagcagcag aaatcaatct ttgataataa tctgccatca atgtttcata
    28261 gatcactgta cttctttctt tatgtgataa gctccgtttc atatcttcat tcacactacg
    28321 tgcctttttc aaccgaccat tttctatata aaacgaagtc aggttcatta aaaaagtaaa
    28381 gagatactgc tcatgattgt tcaactgtgc taatcgtcgc attctttttt tgattttcaa
    28441 ataattgttc tcaatgaacc gatcactgaa tatccaagga aaatcagcta gaatagatag
    28501 ttcaaattga ccatagtctg gtatctgcat caagtattct tcaatgattc ggcattcata
    28561 acgtaaaaat tcaaattctg tctcagatac ttctgttttt tcgaccatgt gaagattcaa
    28621 aaccaaataa tacagatctt ctgttttctt aaaatgccta cggttattgc tgatctcttt
    28681 ataaggatca aagctgtctt cttgtacccg atctagcatt cgtctttttt tctttaactt
    28741 tattggttca tccagctggt ttcgcatcca ttcatattct gcaagtgtca tgttcattcg
    28801 ctctaaaaat gatctcaatg ttacaaatga catttttttc actgaatttg tctcaatccc
    28861 gactagagaa gtcttaaaac agattccttc cgctaattgg gactgtgtca acttcttgtt
    28921 gactcgaagt ttcttgatca attcaccatc atacataata gttctccttt ttaatttaaa
    28981 tttttccaca ttcaataaat agatacgtta aaaaggaaaa atacacgaaa aaaataaaaa
    29041 aatgtttttt tcataaaaaa taccaacctt caagcattag aatgttgtct aactactgaa
    29101 ggttggtttg attgtttatt gattattttt ttgctgttca acgtctgttc ttgttactgg
    29161 atataagttg gttgttgttt tattaccatt ttttgaaaag acacttgtcg aatgttcgcc
    29221 tttttgcttt tcgattgctt cattacgttc cgcttcattt ttatagtcat attttttcgg
    29281 atcaatcgtc tcaaatccgt ttggcacata aaaccgcaag agattttcct gattcagctt
    29341 atctgaaaga cttaacgcag tcttgacttt ttcctgatct ttggagattt cctcatcgat
    29401 tcctgctgct ttcgtatcga tgatttctcc tgtctgatta ttgtaagctt ttcctcctag
    29461 gacggtgtat ttgggtgtca caaagttccc atttcgaaaa gcaactactt gatcatgctg
    29521 agaagataat aagtctgtac caaaatgaag ataatcttta tcatcgattc ccaatagatg
    29581 tagtaatgtc ggcaaaacat cgatttctcc accgtattca tgattgactg tccctttagt
    29641 ataaccaggc atatggatca tcaatggcac tcgttgcatc tgtgcgttgt caaattcatc
    29701 ccatgtatct ggatctttac caagagcgct tgctaaatct ttattatctg tattcgagat
    29761 cccaaaatga tccccgtaaa tcacaaagat tgaattttgg taaataccag attttttcaa
    29821 atacgtaaaa aattgttcca atgattgatc cagataatgt gccgttcgaa cataattatc
    29881 tactgtgcta ttgccagtat tcaaagatgg aaagtcgaaa ttcttgtcat ccgtataata
    29941 aggcgtgtgg ttggttacgg aaagaaattt cgtgtaaaac ggctgttgta gatgctcaag
    30001 atattgggca gattctctga ataaatcttt atctaatatc ccataaccta acgtttcgtc
    30061 ggattcatca aaataagatc gatcaaagaa attgtcataa cctaagtttt tatatacatg
    30121 atctctattc caaaaactag ctacattccc atggaaaaca gcgcttgtat agccttgctt
    30181 ttgtccaagg atcgctggtg cggcttgaaa gacattgtct gacccaagtt ctgtgaataa
    30241 tgagccttga ggtaaaccaa atgtgccagt ttccaacata ttttcagcat cacttgtctt
    30301 tccctgtcct acttcatgaa agaaattgtc aaagctgatc gttgcttgat tctggaaaat
    30361 actatttaaa aacggtgtga cttcttgtcc gtctaccttc atattaatca aaaactgctg
    30421 gaaactttct aaatggagaa cgatcacatt tttcccttta gcgatcccaa atgtttcggg
    30481 atttggctct gcataatgtt tctttgtata atctaaaact tcatcaatcc cattactgct
    30541 tgcatgcgcg cgaacactgc tagtcattcc tgttttgatt ccgtcataaa tagtatacgc
    30601 atcgattcct agatatttga caatatatga acggtcaaat gttcgctgca gcaattgtgg
    30661 acggttggct tcgctcagcg ctagatttcc tgaaaaaata agccctgaaa gacaggtaac
    30721 agcgatagcc atcggtttgc cgacagggtt gcttttgata ggtattttct tgaccttcaa
    30781 ccaaaccagt agcccaatga acacagcgat atccagccag tagatgacat catggggctt
    30841 catcaaagaa aaggagcttc ctgacaatcc ttgcgacact ttcgaaaagc ctaatacaga
    30901 tttgactgta atgaaatctg tgaattcccg ataaaaaata atattcaagt acaacaaaag
    30961 cgtatttaaa atatcaatga tcaaaagaat agctaacgct ggctttggct ttttaatata
    31021 caaagaaagg ccaaaaaaca ataaggtagt cgcaattggg ttgatccaca agataaagta
    31081 ctggatcgta ccttccacac ctaatgaaaa atctgcatag taggcaatga tcgtcttcag
    31141 ccagaaaaag aaaacagctg tcaaaacgat tgctaaacga ttttggcaca attttttaag
    31201 ttgtgtcacg tatatcactt ctctctattc acattttttc ttattttgct cctgaaaaat
    31261 gaaaatttcc taaaaaagtt gttatcttaa gattttttta ttctttctaa agattattcc
    31321 gtccactttt cacagcataa aaccgctgcg atgtaagcga ttaaactaat gaagagataa
    31381 aagtcttgtg gtgaccgctt cactccacgg tattcaaaag ccagtttctc ggtattcgta
    31441 caaaaaaaga ggctgtgaca aaattcttgt cgcagctcct tatttcttga tgcaggacag
    31501 ctttttcaca acttcttcct taaacggtgt tctcctgcca actcctcggc cacaagtcac
    31561 aatatttata aaacatgaga agctgttttt tgaaattgtt ccttgtggct cagagttaaa
    31621 cggcaggctc aagacctctt gatacacggt gttcaatcag ctgaccctcg gtattagatt
    31681 atgtcaggac gctaatttta caacctcttg gtaaacggtg ttcaaaagct tgcatctgcg
    31741 gtaataagcc caaccaaacg aaaaatataa ggagctattt tttgaaattg ctccttgtgg
    31801 ctcagagtta aacggcaggc tcaagacctc ttgatacacg gtgttcaatc agctgacctt
    31861 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgccgtttg tttctctaat
    31921 actcaggtca aaacgctgat ttcacaacct ctgtttttca ttgtccatag gattgatatt
    31981 gtccttgtga tgactcattc gtaataattg aggcttgatt ttcttcactt cccgttatcg
    32041 tttgtccact gccagaatct gaaggacttg ttcctgtcga ctcgtttttt tgagaagaga
    32101 cagttgtttt cttgacttgt tcatttgtct ttttccattc cgctaaacga tcggcgacca
    32161 cttttttgtc tactttttca gaataagcgg tgatcacttt tccatttttc aaacgggcta
    32221 ctttgtcgcc atcatgagtc aaaagcaaaa cggtcaaatg cttgtcttta aattgatatt
    32281 gtctgagaga aatcgcacta agtacgtcat cgatattaat aaattgattt tcttcttttc
    32341 cttttggcaa ataaatgtcc aattcgcctt tttcgtaatt ggcagttatt ttatactccg
    32401 cccaccaata agttgagaat tcttttttga aattatctac tgattctttg cttgctacga
    32461 ttttttctgt ttctttctga gcaagatctg ctgtcatttt tcctgaaaat gctgcggata
    32521 aaataagcag taagaaaaaa ccgaataacc aaaagagaag aaacggtctt tttttcctca
    32581 tgctttcctc cactcctatt taattttgac tattctatta tatacaaaaa atgaaataga
    32641 aagacaaaaa agttgaaaaa gatcgtaaat aattgaactt ctttttcaca aaatggtaag
    32701 aatggagaat ttcacgcatt tgctctcaac tattctttct taagcctcaa atccgttttt
    32761 atctgatacg tctttgaacc aatgacccga ttttttgatt gttctttttc catcttgtgc
    32821 taagtctact gaaataaagc catatcgatt cttatatgca ttggtccacg accagttatc
    32881 catacatgtc cacatatgat agcctaaaca attggcacct tcttgaatgg cttgatggac
    32941 atatttcaga tgagattgga caaattcgat ccgataatca tcgtggatca tgccatcttc
    33001 tttgataaat cgtgcttcgt tttctacacc cataccgttt tcagaaataa agcagtcgat
    33061 atttccataa tgatctcgta cattgatcaa aatatcatag attccttgtt catagatctc
    33121 ccatccgcga taaggattca ttttacgacc aggcatttca taattgtcga aataatcctc
    33181 aggcattgga ccgtttttag tatcgattgg tgtttctttt gcttttaccc ggcgtggctg
    33241 gtaataattg atacctaaaa gatctactgt attttctttg ataaccgtca aatcctctgc
    33301 atggatcaca ggcatgagat caagttcttt tactatctca atcaattcac ttggaaactc
    33361 gccttttaca gctggatcaa ggaatgaacg attgaagaac gcatctgcta tttgcgctgc
    33421 tttaacatct tcagggtttg attcgtctct tggatagctt ggtgtcagat tcaagatgat
    33481 accaataaca ccaccttgct ccatttcatg gtaagatttg atggctaacg ctgaagccaa
    33541 cgcttcatga tagccaactt ggatcgcttt tttcatatct gactcttctg gataatgcca
    33601 tcgatataaa taacctgctt cgactggaac gattggttca ttatgagtaa accatttttt
    33661 tactttcgaa ccaaacaatt caaaacaact tttggcatat ttttcatagg cttcaaccgt
    33721 ttctcggttc aaccatccgc ctttttcttg cagatacatc ggcatatcga aatgatacag
    33781 attcacaaag ggttcgatac cgttttcaat caactcatca aaataacgat gatagaaacg
    33841 aacggcttct tcgttgattg ttccagattc atcaggtatc aaacggctcc attggataga
    33901 tgttcgaaat gaattatgcc cagtctgttt catcaactgt acatcctctt gatacttcgt
    33961 ataaacttgc gaggtttttt caggtcctac ttgatcaaag aacttttgcg gttctttttt
    34021 gtaccaataa tcaaaaatgt tctctccttt tccatcgcct gaaatccttc cttctgtttg
    34081 tgggccactt gctgcagaac cccaccaaaa atttgctgga aattgatatt ttttcatcaa
    34141 agcacctctt tttctttttt agttcgtttt agttgattcc atgtatgata ttttccatca
    34201 caatcacttt ttcattttct tcctcttctt ttttgattcg ttttaacagc tgttctgctg
    34261 ctcgttcccc gattttatct gttggtggcg tgatcgtgat tttcggaagg atactcagat
    34321 cgtttttatc taaataatca tagtgactga acgcaatatc cttcccgatt ctgacacctt
    34381 cttgattgaa acattcgatg gcaccaatcg acatattgta attgctgaca aaaatagcag
    34441 ttgccccttt ttctaataat gcttttgccc cgtaatagcc gctttttcta gaatagtctc
    34501 ctgtaaagac ctctaattgg atcgatggat cattttggac cgcttctttg gctcctgcta
    34561 aacgttctct tgctacgtag tctgtttgag tggcagcaat aaatccgatt tttttatgtc
    34621 cttgttcacc atgatgagcg atcacttttg ctacactttc tcgatcattc actaatattg
    34681 tatcaatacc tgctggtcct tctggacaat tcaatgcgat aactggaata ctcatttttg
    34741 tgagcatttc aaatccagac cactcttctt cggataagaa gacaatcagc ccatcgatca
    34801 catgcttcat caggtattca attttttgtt caattttttc tggctgatcg gcaaacccgc
    34861 ttaataataa gctataccca ttttcttcag ctactctttc gatccctgag acaacttccg
    34921 acccaaaacg gctggaaatc ccgtttatca aaagtccaat agagaagctt cgattattct
    34981 tcaacccttt agcaatgatg ttttctttat agtccaacgc tgaaatcgct tctgctattt
    35041 ttttcatgtt cttttccttc agttgctgac cattcaagta acgggaaact gttcccactg
    35101 aaacaccagc catcttagcc acatcacgga tcgatgccat acattctcac tcctgccagt
    35161 tacatttgat ttctctttct tgttgttcga ttatgatgac cgcattcttt gcatagtgtt
    35221 gcttgtcatc aatatccata taactaaagt cttcagtaga gcaacttcct ctcactatta
    35281 attatactta aacaagtatt tgaaccggtt catttttaat atagcatttt tttaaaagat
    35341 tgcaacactt ttttaaaacg ctttctgaaa gtggcggatt ttttgccttt ttaaaatttt
    35401 attctaaaat ttactctatt tgtgggtgtt ttgtgcgttt ttctcttcca tccgtttgaa
    35461 gttttacatt ccaatggtat aatttcttta tcctatcaaa tgggggaagt attttgaaga
    35521 aattaatcgt actatttatt ttgtctgcgg gacttttgac attgactggc tgtgatttgt
    35581 ttggcggctc tgaccaatcc tcggacgaaa caaccgattc ttctgtctta aaagcggaaa
    35641 aagcagatac caccaacagt gtatatacgc taaaagtacg taaagatatg gatttatccg
    35701 cgggacagtt gacatttaca gataaaaaaa tggaatggac acgcacgtat cagacacaag
    35761 gaactgattc ttctgaatca tctgaagaaa aaacagtgct gacagatatc aagatcacta
    35821 ccaaagatga cgaatatatt atttcaggaa aagaaaataa aaaagaaaca acagtcatat
    35881 ttacaaaaat cggtaattac cgtttgaagg atgaggatgg caacatctac agtctatagt
    35941 gccgtctgtt ggatcttctt ttgtttctcc ccttcttttc tgctatagta aagaagcaag
    36001 atgattgtaa aggagacgaa atggatgatc gatagtcctg attattgtac atgtaataac
    36061 aacaaaaata tccatacaga atttaatgac caaggaagct tgagcatatg cgacaactgt
    36121 cacaaactag tcaaagattc atttaaaaca tttgaatctt atcctgttca aaattatgta
    36181 aaaagtagaa gaagataaac aaatccaagc aaaactcact atggctgatt tttatgaact
    36241 tcaaactcag cttcttcctt tgatcaagct tcatcagtaa aacaaacagt ggatcatttc
    36301 agtttacaaa tcaaagagta aagatttatt tatttcaaat atttgaatat aaaataacca
    36361 aacgatagaa aggcttattc tacatcacgt agtaattttt ctttcccgtc gtttggtttt
    36421 ttatttttag cctaattctt gaccttttgc atgctggtta tccgtaaaat attttccagc
    36481 aggctttcct tccaattcag ctaatttttc ttggatctga cggatcacct tttttgcatc
    36541 ttctggattt tctacaaaat cgaatttatc cccatccact tgtattttag gacatacatc
    36601 aaaatcttca taccattgat tatagcgggt gttcaacgtt tcataatagg tatataacgt
    36661 ctcatcgctt tctagctgtt catagtcacg cccacgtttt ttgatacgtt ctagcatcgt
    36721 gtccaaagaa actttgatat ggaccatcaa atcaggccgt ttttttggag caacatcatc
    36781 taactcgttt agcatcgtat ctaataagct atcgtactgc tgtacttcga tatccgttac
    36841 ccgacctaaa tcagcgttta gatggaacaa caggctatct tcatagatgg atcggtctag
    36901 cacattgtca tcgttcacta aagcattttt cattgctaaa aatcgcttgt tcaaaaagaa
    36961 gatttgcaat aaaaaagcgt actgctcagg atttgaataa aagagcggca atacttcgtt
    37021 atcttcgaca ttttcataaa atggtttaga atcaatctct tttgcaagca tatccgtcaa
    37081 actgctctta cctgcaccaa tcgttcctga aatcaaaatc actgacatac aacccttcct
    37141 cttctataag tactcgccta cgtaagtttc aacaggcaat gtttcaaaat catattcacg
    37201 tacagcttgg tctgatttta aatacgtatg gagactttgt gtaatcatca agttcgtagg
    37261 taccgtctct tcttgtacaa tgatcatcgg ttttttcaac atagttgcca cacctaattc
    37321 gtaagccgtt cctggatcga ttgtttgatg ctcaaagtca aggatagcaa caacaaattc
    37381 tgcatttgtc agttcttcca tatctttttc gtatacttcc tgcgcccatc cagcgctgaa
    37441 tagttcataa ttgctttctt ggtgatgacg tggagagtag aaacttgtga ctgttttgtt
    37501 ttcctccaac gctttttcga tacgacttac tcgatcgatt tgctcctctg aaaaaaatgg
    37561 tcctgctaaa tatatttgac tcattatttt gcctccttca ataataactg atttttaata
    37621 gatactgctc gtaattcatt gaccagttcc aatggattgt tggaaaagat tacttgatcc
    37681 aaccattttt tatccataaa atcctctttt gcaaaagttt ctaataattg ttgcaagccg
    37741 ctgtaataac cgccaatatt caatattccg attggcttgt cgggcgtcag accgattgct
    37801 atccaagaaa gaagttgtga gaattcctcc aatgtaccta gacctccagg gaaaacgagg
    37861 acagcatctc ccttttcaaa taataatacc tttctttcat cgatcgtttc tgtaggaata
    37921 aatgtagtaa catcttttcc aggcaattca gtttcaaaaa gcccattcgg atagatacct
    37981 gtgacttttc cgttattttc cagtactgtt ttactaatca ctcccataat cccggagtat
    38041 gaaccaccgt aaaccagttc gatttcttct tgtgccatgt attttcctaa cgtttgcgca
    38101 ataaatttgt aactttcttt attaccaaaa cgggaaccgc aaaaaacagt aagtttcata
    38161 aaaaaacact ccctaactca aaagtctatc ttcattctac acgtgttttt ttaaaataaa
    38221 agactagatt ttgtagtttt ttagtggtat atagg
//
LOCUS       DADVXK010000013        37345 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.013, whole genome shotgun sequence.
ACCESSION   DADVXK010000013 DADVXK010000000
VERSION     DADVXK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.013"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(12..617)
                     /gene="dhaL"
                     /locus_tag="KB909_000673"
     CDS             complement(12..617)
                     /gene="dhaL"
                     /locus_tag="KB909_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBB6836731.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="KB909_000674"
     CDS             complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="KB909_000674"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBB6836732.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="KB909_000675"
     CDS             complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="KB909_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBB6836733.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            2179..2499
                     /locus_tag="KB909_000676"
     CDS             2179..2499
                     /locus_tag="KB909_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBB6836734.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(2611..3480)
                     /locus_tag="KB909_000677"
     CDS             complement(2611..3480)
                     /locus_tag="KB909_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6836735.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(3576..4880)
                     /locus_tag="KB909_000678"
     CDS             complement(3576..4880)
                     /locus_tag="KB909_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6836736.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(4877..5386)
                     /locus_tag="KB909_000679"
     CDS             complement(4877..5386)
                     /locus_tag="KB909_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836737.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(5561..7696)
                     /locus_tag="KB909_000680"
     CDS             complement(5561..7696)
                     /locus_tag="KB909_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6836738.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(7779..9434)
                     /locus_tag="KB909_000681"
     CDS             complement(7779..9434)
                     /locus_tag="KB909_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6836739.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(9436..9750)
                     /locus_tag="KB909_000682"
     CDS             complement(9436..9750)
                     /locus_tag="KB909_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6836740.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            9920..10180
                     /locus_tag="KB909_000683"
     CDS             9920..10180
                     /locus_tag="KB909_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBB6836741.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            10194..10508
                     /locus_tag="KB909_000684"
     CDS             10194..10508
                     /locus_tag="KB909_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBB6836742.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(11238..11792)
                     /locus_tag="KB909_000685"
     CDS             complement(11238..11792)
                     /locus_tag="KB909_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBB6836743.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(11918..13847)
                     /locus_tag="KB909_000686"
                     /pseudo
     CDS             complement(11918..13847)
                     /locus_tag="KB909_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(14153..14869)
                     /locus_tag="KB909_000687"
     CDS             complement(14153..14869)
                     /locus_tag="KB909_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6836744.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="KB909_000688"
     CDS             complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="KB909_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBB6836745.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="KB909_000689"
     CDS             complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="KB909_000689"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBB6836746.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(18339..19799)
                     /locus_tag="KB909_000690"
     CDS             complement(18339..19799)
                     /locus_tag="KB909_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836747.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(19789..21084)
                     /locus_tag="KB909_000691"
     CDS             complement(19789..21084)
                     /locus_tag="KB909_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6836748.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(21416..22093)
                     /locus_tag="KB909_000692"
     CDS             complement(21416..22093)
                     /locus_tag="KB909_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBB6836749.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22123..23214)
                     /locus_tag="KB909_000693"
     CDS             complement(22123..23214)
                     /locus_tag="KB909_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBB6836750.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(23315..23749)
                     /locus_tag="KB909_000694"
     CDS             complement(23315..23749)
                     /locus_tag="KB909_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6836751.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="KB909_000695"
     CDS             complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="KB909_000695"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6836752.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EWVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(25787..27682)
                     /locus_tag="KB909_000696"
     CDS             complement(25787..27682)
                     /locus_tag="KB909_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6836753.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(27740..29515)
                     /locus_tag="KB909_000697"
     CDS             complement(27740..29515)
                     /locus_tag="KB909_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6836754.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(29565..31061)
                     /locus_tag="KB909_000698"
     CDS             complement(29565..31061)
                     /locus_tag="KB909_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6836755.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(31255..32877)
                     /locus_tag="KB909_000699"
     CDS             complement(31255..32877)
                     /locus_tag="KB909_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6836756.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(33205..34518)
                     /locus_tag="KB909_000700"
     CDS             complement(33205..34518)
                     /locus_tag="KB909_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6836757.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(34763..34987)
                     /locus_tag="KB909_000701"
     CDS             complement(34763..34987)
                     /locus_tag="KB909_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836758.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35007..35429)
                     /locus_tag="KB909_000702"
     CDS             complement(35007..35429)
                     /locus_tag="KB909_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBB6836759.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(35571..36281)
                     /locus_tag="KB909_000703"
     CDS             complement(35571..36281)
                     /locus_tag="KB909_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836760.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(36299..36796)
                     /locus_tag="KB909_000704"
     CDS             complement(36299..36796)
                     /locus_tag="KB909_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836761.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(36833..37285)
                     /locus_tag="KB909_000705"
     CDS             complement(36833..37285)
                     /locus_tag="KB909_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6836762.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
BASE COUNT        10531 a         8038 c         6282 g        12494 t
ORIGIN      
        1 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
       61 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
      121 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
      181 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
      241 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
      301 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
      361 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
      421 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
      481 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
      541 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
      601 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
      661 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
      721 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
      781 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
      841 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
      901 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
      961 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     1021 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     1081 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     1141 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     1201 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     1261 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     1321 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     1381 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     1441 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     1501 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     1561 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     1621 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     1681 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     1741 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     1801 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     1861 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     1921 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     1981 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     2041 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     2101 aaatttctaa ttttgggaaa atatgtgtag tgcttcttga agtttgttat actttaatta
     2161 aaagagagga gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta
     2221 gtagcttata aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac
     2281 ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta
     2341 atgggtgcaa gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct
     2401 gatgcgatca ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg
     2461 atggtcacat gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat
     2521 aactaaagag agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc
     2581 gaggtactct accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc
     2641 tgctgcgact aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt
     2701 tgtttttggc aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc
     2761 tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg
     2821 ttggaaacta gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc
     2881 ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact
     2941 tagctttcca gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg
     3001 ttggatcttc ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag
     3061 ctttttctca agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg
     3121 atcgattgct gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag
     3181 ttcttttctt ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact
     3241 atttattgat gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt
     3301 ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga
     3361 aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat
     3421 actggaaaca gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat
     3481 ccttactact ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac
     3541 acaacaggct gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt
     3601 ttccatgtcc cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg
     3661 atcgttatcg cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat
     3721 ttcaattttc ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg
     3781 accatttcaa agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag
     3841 tttccttgat atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag
     3901 aatattgacc agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt
     3961 ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt
     4021 gcccaacgtt ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag
     4081 ataatctcag gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg
     4141 atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga
     4201 tacatcgtat ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt
     4261 ttaatgatgc ccacgatact tgagaattca accgtttgag attttgcaat caatttggta
     4321 cgattttgga catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg
     4381 aaataattca catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt
     4441 aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta
     4501 tttttttcga tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt
     4561 tctggtgttt ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc
     4621 aatttcgtca tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc
     4681 accatgatcg tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta
     4741 tgtttgtata aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc
     4801 ggataagaaa cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct
     4861 gtatgggtga ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga
     4921 atgtcgtatc tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt
     4981 cttttgttcc aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt
     5041 tttcatcttc atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc
     5101 tagtcaatac aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta
     5161 agaaatacag cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt
     5221 ctggtctcgt taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta
     5281 aaagagccac taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat
     5341 ctttcaccaa aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg
     5401 tttttttgtt acgacgtagg agtttaccat acatttcatt tcttttcaca taaagtgttc
     5461 ctaaattttt cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg
     5521 ttctttttat cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata
     5581 cgacaatgct tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct
     5641 catctccatc gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta
     5701 gactcaaagg aatgatttgg cagttttcta atccatatga atttttttta atcgattctt
     5761 gtagcgtttg ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag
     5821 aaaccaaaat ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt
     5881 cgggttcttt tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat
     5941 aggttttgaa aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc
     6001 gatggatcgg cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag
     6061 aattaaagat tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt
     6121 cgatcaatag acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc
     6181 gaaatgctgg tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg
     6241 cttcatcaac agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa
     6301 ttctttcaaa caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt
     6361 ttcgatattt tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat
     6421 cagaaatcaa tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat
     6481 tctgcacagc aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg
     6541 cctttttcgt tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata
     6601 ttttttcgat cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa
     6661 aattcggatg atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc
     6721 tacgcaaacg ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct
     6781 cttcaccttc tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca
     6841 gtggatttct ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat
     6901 taggtgatag aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat
     6961 acgcaatacg ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga
     7021 tattttgact tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga
     7081 tagccttcat ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa
     7141 tagctacaga cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc
     7201 tttctttaat aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca
     7261 tgttattgta aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg
     7321 catcatctgt gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa
     7381 agtctacaac gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct
     7441 gattttctgc gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa
     7501 tcatcgaaaa agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag
     7561 ccatttcttt caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt
     7621 cgtttttttt atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt
     7681 tttgtgtgtt gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta
     7741 cctcttttaa gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt
     7801 tcttcaggtc ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag
     7861 ccagactgct tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg
     7921 atatattctt gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata
     7981 tgtttggctt ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa
     8041 atttttcctt ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct
     8101 tctgcaatgt tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat
     8161 ggcggtgcat acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt
     8221 gctgttgcta aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca
     8281 taaatctcgc cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga
     8341 taatagcttg catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct
     8401 ttggctgttc tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt
     8461 gctgttccaa taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt
     8521 ctaccttgac gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc
     8581 tgttttacaa cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt
     8641 tcgtctacta ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg
     8701 ttatcaggac gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca
     8761 tccagtcgca atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact
     8821 tctactcctt gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt
     8881 ggaagaatat gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt
     8941 tctgccattt ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt
     9001 tctaatgcat gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg
     9061 gcttctgtta tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat
     9121 gcatcgtact gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg
     9181 ggaaagatgg ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat
     9241 gattctggcg tttggacaag aagattttcc cgttcactga tttctcccga aagataataa
     9301 ggcaagccgc aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca
     9361 tcttccatta atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca
     9421 ataacgattt tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc
     9481 acgtacattc actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct
     9541 catccctgat tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat
     9601 actttgtaat ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt
     9661 tctaacatca agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat
     9721 cgattttatt gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat
     9781 acctcatggg gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat
     9841 ttttttcact actttttata tttgcataaa ataccgataa ggggtattat ctaattataa
     9901 aaatagagga gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg
     9961 tacagaggga caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga
    10021 tgtcatcact caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt
    10081 tgcagataat ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc
    10141 taaactagaa caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag
    10201 tcgttttcca tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc
    10261 tgataaaagc ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg
    10321 gttatctaga ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt
    10381 gcgccaatgc tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg
    10441 ttgtaccagc aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca
    10501 agccttagtc agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt
    10561 ttcgaagaag ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat
    10621 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta
    10681 ttaccgcaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt
    10741 gacctaagta ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag
    10801 ctaataccga aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct
    10861 tagtttcgag tattaagaaa aattttgtga aaatggattt ctacattttt gcataaattt
    10921 ggcttaatac cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc
    10981 ggtttgacct gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt
    11041 ttgagctaat accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac
    11101 catttaactc cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg
    11161 ttggcttatt atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca
    11221 taggtcacac ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag
    11281 acaaaagatt gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt
    11341 ggtaattctg ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact
    11401 ttgccatacc acttcgctcc acttaatttg atatttttag atagcccgat taatccagct
    11461 acaaacataa agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga
    11521 taccatgcca tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc
    11581 accttcccta agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca
    11641 gacaaacctg agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa
    11701 taaagataaa tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt
    11761 atttctttac gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt
    11821 ttctttttat tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc
    11881 tttacagaca ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta
    11941 ctcttctttc ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg
    12001 atcctcgctc taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta
    12061 aatcgtaacc tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag
    12121 gcacgtggat tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat
    12181 aaactaacgc ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct
    12241 gacgttcttt tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt
    12301 tctgtgtccg ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg
    12361 acatatccat tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc
    12421 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
    12481 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    12541 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    12601 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    12661 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    12721 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    12781 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    12841 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    12901 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    12961 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    13021 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    13081 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    13141 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    13201 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    13261 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    13321 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    13381 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    13441 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    13501 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    13561 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    13621 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    13681 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    13741 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    13801 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    13861 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    13921 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    13981 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    14041 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    14101 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    14161 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    14221 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    14281 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    14341 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    14401 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    14461 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    14521 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    14581 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    14641 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    14701 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    14761 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    14821 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    14881 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    14941 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    15001 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    15061 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    15121 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    15181 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    15241 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    15301 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    15361 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    15421 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    15481 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    15541 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    15601 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    15661 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    15721 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    15781 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    15841 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    15901 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    15961 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    16021 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    16081 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    16141 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    16201 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    16261 gtgtcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    16321 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    16381 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    16441 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    16501 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    16561 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    16621 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    16681 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    16741 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    16801 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    16861 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    16921 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    16981 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    17041 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    17101 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    17161 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    17221 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    17281 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    17341 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    17401 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    17461 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    17521 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    17581 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    17641 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    17701 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    17761 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    17821 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    17881 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    17941 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    18001 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    18061 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    18121 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    18181 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    18241 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    18301 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    18361 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    18421 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    18481 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    18541 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    18601 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    18661 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    18721 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    18781 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    18841 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    18901 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    18961 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    19021 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    19081 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    19141 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    19201 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    19261 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    19321 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    19381 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    19441 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    19501 tagacgagca tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa
    19561 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    19621 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    19681 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    19741 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    19801 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    19861 tagctcatgt tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg
    19921 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    19981 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    20041 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    20101 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    20161 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    20221 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    20281 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    20341 attcaatgtt aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa
    20401 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    20461 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    20521 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    20581 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    20641 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    20701 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    20761 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    20821 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    20881 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    20941 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    21001 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    21061 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    21121 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    21181 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    21241 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    21301 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    21361 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    21421 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    21481 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    21541 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    21601 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    21661 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    21721 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    21781 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    21841 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    21901 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    21961 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    22021 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    22081 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    22141 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttttt caaaaggttt
    22201 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    22261 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    22321 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    22381 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    22441 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    22501 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    22561 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    22621 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    22681 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    22741 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    22801 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    22861 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    22921 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    22981 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    23041 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    23101 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    23161 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    23221 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    23281 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    23341 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    23401 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    23461 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    23521 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    23581 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    23641 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    23701 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    23761 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    23821 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    23881 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    23941 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    24001 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    24061 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    24121 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    24181 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    24241 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    24301 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    24361 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    24421 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    24481 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct
    24541 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    24601 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    24661 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    24721 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    24781 acccattccc aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    24841 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    24901 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    24961 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    25021 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    25081 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    25141 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    25201 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    25261 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    25321 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    25381 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    25441 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    25501 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    25561 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    25621 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    25681 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    25741 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    25801 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    25861 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    25921 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    25981 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    26041 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    26101 ccccgtttac agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    26161 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    26221 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    26281 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    26341 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    26401 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    26461 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    26521 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    26581 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    26641 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    26701 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    26761 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    26821 ctacaactaa taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    26881 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    26941 cagctaaaat tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta
    27001 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    27061 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    27121 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    27181 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    27241 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    27301 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    27361 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    27421 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    27481 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    27541 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    27601 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    27661 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    27721 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    27781 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    27841 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    27901 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    27961 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    28021 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    28081 tctgataaat ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    28141 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    28201 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    28261 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    28321 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat
    28381 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    28441 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    28501 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    28561 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    28621 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    28681 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    28741 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    28801 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    28861 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    28921 gcatgatatt ggaaaaaatt gtactgattt gttgaggaaa ccttgcgtgt tggatcaccg
    28981 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    29041 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    29101 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    29161 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    29221 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    29281 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    29341 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    29401 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    29461 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    29521 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    29581 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    29641 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    29701 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    29761 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    29821 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    29881 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    29941 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    30001 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    30061 ttatagacag cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag
    30121 cactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa
    30181 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    30241 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    30301 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    30361 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt
    30421 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    30481 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    30541 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    30601 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    30661 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    30721 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    30781 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    30841 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    30901 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    30961 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    31021 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    31081 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    31141 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    31201 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    31261 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    31321 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt
    31381 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    31441 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    31501 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    31561 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    31621 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    31681 tttcgccttg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    31741 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    31801 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    31861 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    31921 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    31981 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    32041 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    32101 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    32161 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    32221 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    32281 gtccatacga aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    32341 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    32401 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    32461 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    32521 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    32581 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    32641 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    32701 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    32761 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    32821 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    32881 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    32941 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    33001 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga
    33061 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta
    33121 gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc
    33181 cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa
    33241 tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat
    33301 ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg
    33361 catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg
    33421 tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga
    33481 agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt
    33541 aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc
    33601 accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa
    33661 agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc
    33721 aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca
    33781 catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa
    33841 acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa
    33901 aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat
    33961 agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa
    34021 tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc
    34081 gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat
    34141 gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac
    34201 gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa
    34261 agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa
    34321 aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc
    34381 agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt
    34441 aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga
    34501 aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt
    34561 aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt
    34621 aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat
    34681 ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt
    34741 ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt
    34801 cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg
    34861 tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc
    34921 gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta
    34981 gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa
    35041 taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct
    35101 cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa
    35161 ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct
    35221 aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt
    35281 gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca
    35341 ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat
    35401 tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt
    35461 gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt
    35521 tttacaaaaa aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct
    35581 gcttctgatt catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg
    35641 attttttcct tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg
    35701 gattcaatga ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca
    35761 cgccagttga gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga
    35821 agtgccggag catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt
    35881 cctaaatgca gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa
    35941 gacaaggaaa tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct
    36001 tgatttgcac gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat
    36061 gtggtaaatg cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta
    36121 aggtaatttc ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt
    36181 tcttttgtta cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga
    36241 aatacttccc agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt
    36301 agaataattg cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat
    36361 gttcgctgta tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt
    36421 cccaaacacc gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat
    36481 ctagtaaaaa tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga
    36541 tttctaaaaa atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt
    36601 aacccgcagg ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct
    36661 cttctgtaag tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg
    36721 aattatcttt tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta
    36781 catctgaagg cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga
    36841 tccttttatt gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat
    36901 ttaaaagata ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat
    36961 tggagtagtt gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat
    37021 agagtttctt gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt
    37081 ctaatttctt gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt
    37141 tttcttggat gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg
    37201 ttaaatcgac ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc
    37261 cgatgtctcg aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt
    37321 cacctctttt tgttgcaaat gcaac
//
LOCUS       DADVXK010000014        35481 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.014, whole genome shotgun sequence.
ACCESSION   DADVXK010000014 DADVXK010000000
VERSION     DADVXK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.014"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            161..1927
                     /locus_tag="KB909_000706"
     CDS             161..1927
                     /locus_tag="KB909_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBB6836763.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2029..3288
                     /locus_tag="KB909_000707"
     CDS             2029..3288
                     /locus_tag="KB909_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6836764.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3435..4736
                     /locus_tag="KB909_000708"
     CDS             3435..4736
                     /locus_tag="KB909_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836765.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4739..5590
                     /locus_tag="KB909_000709"
     CDS             4739..5590
                     /locus_tag="KB909_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836766.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5603..6418
                     /locus_tag="KB909_000710"
     CDS             5603..6418
                     /locus_tag="KB909_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBB6836767.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6569..7735
                     /locus_tag="KB909_000711"
     CDS             6569..7735
                     /locus_tag="KB909_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6836768.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            7965..8612
                     /locus_tag="KB909_000712"
     CDS             7965..8612
                     /locus_tag="KB909_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6836769.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8696..9640
                     /locus_tag="KB909_000713"
     CDS             8696..9640
                     /locus_tag="KB909_000713"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBB6836770.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9775..11226
                     /locus_tag="KB909_000714"
     CDS             9775..11226
                     /locus_tag="KB909_000714"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBB6836771.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11247..12083
                     /locus_tag="KB909_000715"
     CDS             11247..12083
                     /locus_tag="KB909_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6836772.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12083..12742
                     /locus_tag="KB909_000716"
     CDS             12083..12742
                     /locus_tag="KB909_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6836773.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            12868..13557
                     /locus_tag="KB909_000717"
     CDS             12868..13557
                     /locus_tag="KB909_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836774.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13563..14519
                     /locus_tag="KB909_000718"
     CDS             13563..14519
                     /locus_tag="KB909_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBB6836775.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14563..15075
                     /locus_tag="KB909_000719"
     CDS             14563..15075
                     /locus_tag="KB909_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836776.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15331..15879)
                     /locus_tag="KB909_000720"
     CDS             complement(15331..15879)
                     /locus_tag="KB909_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6836777.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(15968..17149)
                     /locus_tag="KB909_000721"
     CDS             complement(15968..17149)
                     /locus_tag="KB909_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBB6836778.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17385..18893)
                     /locus_tag="KB909_000722"
     CDS             complement(17385..18893)
                     /locus_tag="KB909_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBB6836779.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19052..19243
                     /locus_tag="KB909_000723"
     CDS             19052..19243
                     /locus_tag="KB909_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836780.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19446..20363
                     /locus_tag="KB909_000724"
     CDS             19446..20363
                     /locus_tag="KB909_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBB6836781.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20356..21429
                     /locus_tag="KB909_000725"
     CDS             20356..21429
                     /locus_tag="KB909_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836782.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21577..22095
                     /locus_tag="KB909_000726"
     CDS             21577..22095
                     /locus_tag="KB909_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836783.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22076..22468
                     /locus_tag="KB909_000727"
     CDS             22076..22468
                     /locus_tag="KB909_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBB6836784.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22544..23479
                     /locus_tag="KB909_000728"
     CDS             22544..23479
                     /locus_tag="KB909_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBB6836785.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23612..24391
                     /locus_tag="KB909_000729"
     CDS             23612..24391
                     /locus_tag="KB909_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6836786.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24384..24701
                     /locus_tag="KB909_000730"
     CDS             24384..24701
                     /locus_tag="KB909_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6836787.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            24945..26555
                     /locus_tag="KB909_000731"
     CDS             24945..26555
                     /locus_tag="KB909_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6836788.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26712..27560
                     /locus_tag="KB909_000732"
     CDS             26712..27560
                     /locus_tag="KB909_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6836789.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            27791..28270
                     /locus_tag="KB909_000733"
     CDS             27791..28270
                     /locus_tag="KB909_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836790.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            28303..30531
                     /locus_tag="KB909_000734"
     CDS             28303..30531
                     /locus_tag="KB909_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6836791.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            30660..32303
                     /locus_tag="KB909_000735"
     CDS             30660..32303
                     /locus_tag="KB909_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6836792.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(32376..32921)
                     /locus_tag="KB909_000736"
     CDS             complement(32376..32921)
                     /locus_tag="KB909_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBB6836793.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(32944..33429)
                     /locus_tag="KB909_000737"
     CDS             complement(32944..33429)
                     /locus_tag="KB909_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6836794.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(33419..34231)
                     /locus_tag="KB909_000738"
     CDS             complement(33419..34231)
                     /locus_tag="KB909_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBB6836795.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(34370..>35481)
                     /locus_tag="KB909_000739"
     CDS             complement(34370..>35481)
                     /locus_tag="KB909_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBB6836796.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        11602 a         6389 c         7097 g        10393 t
ORIGIN      
        1 ctaaaacttt taaaagtttt aagtctatct atttggcaag tttaaaaaat aaaaattcgg
       61 tatcaaaaaa ctgttaccga taacattttt gaaagcgttg tcttttgctt ctctatcact
      121 tatagtgatg acgtcatatt aaaacacaag gaggaaatca atggatacag ctgcaattta
      181 tcatcgaccg gaaagtgaat atgcatttct atatacgaat acaagatttc gtattcggct
      241 tcgtactagg aaaaatgata tcaaaaaagt atatgtgcta tgtggagatc catataccat
      301 aacaactgaa aaatggtatc aaaaacaacg accaatgaaa aaatgtctaa gtaccaatgt
      361 tcatgattat tgggaaattg aagtgacgag cgaaacaagt cgcttacagt atgcgttcca
      421 tgttgttggg gaagataaca cggactgttt ttacggtgat caaggaattt ttccttatcg
      481 agaaaatgtg attactgaac caaattttta ttttcgaata ccttattttc atcaaatcga
      541 tcgattcact attccagaat gggtaaaaga aacagtatgg tatcaaattt ttcccgaaag
      601 atttgcaaac ggggacaaag caaatgaccc cgaacacact ttaccttggg gaagtaaaga
      661 tccagaccga gaagactttt tcgggggaga tttgcaaggt gtgatggatc atttggatta
      721 cttgacggac cttggcatca atggcatcta tttttgtccc atatttaaag ccacatccaa
      781 tcataaatac gatacgattg attattatga ggtggatccc gcttttggcg ataaaaaact
      841 tttaaaaaac ttgattgatg aagcacataa aagagggata cgtatcatgt tcgatgctgt
      901 attcaatcat atgggtgtcc attcaccaca gtggcaagac gttctcaaaa acggagaaaa
      961 atcgatctat aaagactggt tccacatccg ttttttccca gtagattctt atcagatgac
     1021 tgacttacca gaaactgctg aaaatatccc atatgatact tttgctttta ctccattcat
     1081 gccgaaacta aatacagcaa atccagaagt gcaaaaatat ttgctggata tcgcaactta
     1141 ttggataaaa gaattcgata ttgatggatg gcgtcttgat gttgctaatg aagtcgatca
     1201 tcatttttgg aaaaaattca gagaagcagt tacagaaatc aaaccagaca tctatatcct
     1261 tggagagatt tggcattcct ctcaagcttg gctgcaaggg gatgaattcc atgcagtgat
     1321 gaattatgca tttacagatt cgattaaaga ttattttgca aaaaagaaaa tcacagcttc
     1381 acaaatggtc agtggaatga atcatcagca aatgctttac agagatcagg tgaacgaagg
     1441 aacattcaac ttattagatt ctcatgatac tgccaggatc ttgacccttt gccaaggtaa
     1501 caaagaattg atgaagtctg tgatggcctt tatgtttctt caaaaagggt ctccttgtat
     1561 ctattacggg acagaaatag ggatgactgg tgaagatgac ccggattgcc gcaaatgtat
     1621 gatatgggag aaggaggaac aagatctaga gctattcggt tttataaaag aacttgtttc
     1681 tctaaggaaa cagttgtcta agattatttc tgaaggttct actcagtggc taatagtaaa
     1741 tgatcgtgaa gataagctct atttcacacg gaaactagag ggacagatca tctatgttta
     1801 ctttaatcag tcaaaagaac cttgggtagt agaacaggaa aatgaggtga ttcttagtca
     1861 aaattgtcag ttgttagaag acgggaaagc agagatacga caatacggat ttttgatcat
     1921 gtgttgaaaa ctgttaccgg taacaacaag aaagcgtttg caaatgaaga tttgtgccca
     1981 ttataataag ggtgtaacag cacgttgaat acaaaggagg aaatgaagat gaaaaaaaga
     2041 agtgtgaaac agttgggttt agggttaatc tctttaggaa tcttaggcgg attagcggct
     2101 tgtggcaatg gtaactcttc agcagaaggg gaagccgatg aaggaaaaac gttaacagtt
     2161 tccgttgatt ctggatataa agattatata aacgaaataa aaaacacttt cgaaaaagaa
     2221 aacgatgtga aaatcaagct agtagaaaag gacatgttcg atcagttgga atcattagcg
     2281 ttagatgggc ctgctggaaa gggacctgac gttatgatgg cagcatatga ccggatcggt
     2341 gcgttaggac agcaaggaca tctggcggaa gtaaaactgg gaaatgaagc agcttacgat
     2401 gaaacagaca aagcccaagt gacttatgat ggaaaaatct acggagaacc tgcagtaatc
     2461 gagacccttg ttttgtacta taacaaagat ttagtcgata cagcaccatc aacgtttaaa
     2521 gatttggaga atctatccaa agacagtcgt tttgcttttg agtcagaagc aggaaaaaat
     2581 acaggatttt tagctaaatg gactgacttt tattattcct atggtttaat tgcaggttac
     2641 ggtggctatg tatttggtga tgatggcaca aatccttcag atatcggttt gaataatgca
     2701 ggtgctgtag aaggaatctc ttatgcaaca gattggttca aaaatgtttg gccaaaggga
     2761 atgcaagaca taaaaagtgc aggagacttc gccagccagc aattcatgtc caataaaact
     2821 gcagcaatca ttgacggtcc atggcaagcg caaacataca aagaaaacaa tatcaattat
     2881 ggtgtagcca aaattcctac tctaaataat ggacagcctt atcaaccgtt tggcggagga
     2941 aaaggatggg tagtcagcaa ttatgctaaa aacaaagacc tctctcaaaa atggcttgat
     3001 tatgtaacga atcaggaaaa tcaagaaaaa ttctttgaaa tggtaaatga aatccctgca
     3061 aaccaacaag ctagggaaac agcaaaggct aaaaacgatg aattaacaac agctgtgatt
     3121 gaacaatatg aaacagctca agcgatgcca aacatcccag aaatgggcga agtttggaca
     3181 ggtgcagaaa acttgatgtt cgatgcagca tcaggttcaa aaacaccaaa agaatccgca
     3241 gatgaagcag taaaaacaat cagtgaagcc atagaacaaa aatactgatt aaaatgataa
     3301 ccgtccattt ttataaaaaa tggaacaggt gcttcagata aaagtggcaa gagcgagatg
     3361 gaaaattatc ttgctcttgt tgccattatc ttaaaagcag tttgcggttt agcaagttta
     3421 gagggggcat tcagatgcag caagataaaa caagcaatat caacgaaaaa aaaatcacgc
     3481 tttgttcact tattccaggg atggggcagt ttgtaaatgg ccaagctttt aaaggtatcg
     3541 tttttttcgc catattcgtc ctattcattg gtcagatgct tctgggcgga tttcatgcat
     3601 tggtaggatt ggttactttg ggaagtatac caatggaaga tcattcatta tttattttga
     3661 ttgaaggcac tttgcaattc atcattacaa tcattttctt gattttttac ggtttgaatc
     3721 ttttagacgc ttatcgagta gcgaagatgc gtcaagaggg caaaaaaatc aatcggacga
     3781 tgaaggaagt catacataat ataggtgatg aaggttttcc ttatctattg acacttcccg
     3841 cttatcttct catgattttt acgatcattt tcccagtcct agttacattg ttcactgcat
     3901 ttactaatta tgacttcaat catattccac cagccagttt aattgattgg gtaggggcta
     3961 aaaacttttt tagtatcttc tttttaagct catatcgtaa tacttttttt gcagtctttt
     4021 cgtggaccgt gatttggact ttatgtgcaa caactttgca aatcaccctt ggtattctca
     4081 cagcggttgt tgctcaccag aaatttatta aattcaaacg tattttcggt atcattttct
     4141 tattaccatg ggcggtccca gcttttatta ctatcatgag tttttcgaat atattcaacg
     4201 atagcgtagg tgccatcaat actcaagtga ttcctttcat aaaccagctt ccttttgtag
     4261 atatcagtgc aatctcttgg aaaacggacc cgaactggac gaaagtagca attatcttag
     4321 tgcagggctg gttaggattt ccctatatct atgtgatggt tacaggaatc ttacaatcga
     4381 tttcagaaga cttatatgaa gcagcaaaaa tcgacggagc aaatgcatgg cagcgctttt
     4441 caaacatcac gcttcctgct gtcttcctag tggcagcgcc aacatttatt acacagtata
     4501 cggggaattt caataatttc tccatgatct atctgtttaa caatggcggt cccggaagcg
     4561 taggcggagg agctggttct actgatattc ttatttcctg gatctataaa cttacgactg
     4621 gaacttctcc gcagtattct atggcttcag caatcacgtt gattatctcc gtcatcgtta
     4681 tctgtgtgtc attgctggta tttaaaaaga caaatgcgtt caatatgggg gattaacaat
     4741 gaaaaaattt cattcgagtg ctcgattcca aaaacgactt tctcactttt ttacttactt
     4801 ttttctttta atactgtcag tcattatcat ctatccgctt ttgatcacag caagtactgc
     4861 cttcaagtca ggaaatattg cagcttttag tttagatctt tcaagtgact ggactttagg
     4921 aaactttact cggctattca gtgaaacact ttacgggact tggtataaaa atacattgat
     4981 catttctgtc ctaacaatga tcgtacaagt gactgtagta actttggcgg gctatactta
     5041 tagtcgctat cgttttatcg gccgcaaatc aagtctgatg ttctttttag tgattcagat
     5101 ggtaccgact atggcagcat tgactgcctt ttatgtcatg gctttcttat tagaagcgct
     5161 cgataagtac tggttcttga caatgatcta tataggcggt ggaattccaa tgaatacttg
     5221 gctgatgaaa ggatactttg acactgtacc aatagattta gatgaatctg ctaaacttga
     5281 tggggcaggg catttcagga tttttttcca gattgtatta ccgcttgtca aaccgatgct
     5341 cgccgttcaa gcattatggg cttttatggg accttttggg gatttcatgt tagctaagtt
     5401 cctgcttcga acacctgaaa atcagactgt tgctgtcggc ttacaaacat ttatttctga
     5461 tgtgacaaac caaagagtct ctctttttgc tgctggggca attttgattg cactaccgat
     5521 ttgtctatta ttcttctttt tacaaaagaa ctttgttacc ggcctgacat ctggcggaac
     5581 aaaaggatag gagcagagta tcatgcaaac atttccgtta aactattttt ccgcattacg
     5641 tacgccaact caagtgtttg cgggacgcaa actattatca tggcctaaat ttttcttgat
     5701 atttgtattt ttagtttcct tgatggtcat gcctgtgact cttttttatg ccaatcagat
     5761 ccaagcgatt ccattagaac aatttctatc cgttcattcg ctgatcgatg aacaaggaac
     5821 ccaaaaattt tctgaacttg aattatctga aactgggtta caagcatcgc aacaaacgat
     5881 agctgtgacc cctgaaattt tggtaggtgt gtctttatct gagaaacaac aatccgatca
     5941 tggaactttt attgattttg agaaggaaca atgggtgatc caacaaaagg ataaatctgg
     6001 tatacgccgc tatacgatga attatagccc atctttccaa ccagattctg tacgtacgcc
     6061 cgaagatttc caacgatttt tagaaagaga attttatgcc agtaatcgtc caacaatcat
     6121 tttatcttat agtttaagtc ttggtcttgt cctatttgtc atgacgagtc tcattttatt
     6181 cggggcttcc tttttcttgt ggatgacaag aaaaagccaa ctttcatcca ttcatacatt
     6241 caaagagagt gcaaatttga tgctgaatgt tatgggaata ggttccatgg cagcagcagt
     6301 tgtagggttt atccactttg actttatctt gatgctaagt gtccaaacaa cgataactgt
     6361 cttgctgctt ttatgggttt ttgtcaaaac aagattcaaa gataagcgtg tcgaatgaca
     6421 agtttaagcg atttatgcga caatgaatgt gaaaaaaatg aaaaataaag tagtttttga
     6481 aaaatttctg aaaaaattaa acttcttagt tgattctttt cttttttagt attaacgtaa
     6541 tagggtagtt tttttaagga ggaaaatcat gttagagaaa actttataca atcaattatt
     6601 ttcacgttct ttctcgctcc ctgtcgaagt aaattattgg gacggtacaa cgaaacaata
     6661 cggagatacg gacactcctc cccaaatcaa aatcaatatc catgaagaaa tcccaatgaa
     6721 agagattaca agtaacgcat ctttggcact aggagaagcc tatatggatc atcgaatcga
     6781 gatcgaggga agtatccaag cattgatcaa cgatgcttat cagcaagcaa acagcttttt
     6841 acgaggaaaa gattatctaa aatggctgcc aaagaaagaa aaacatacga aacaaaaaaa
     6901 caaagaagat atccatgcgc attatgactt aggtaacgac ttttataaac tttggctaga
     6961 tccaactttg acttattctt gtgcttattt caatacacct gaagatacgt tggaacaagc
     7021 acaaatcaat aaagtccatc atatcttaga caaactcttt atcaaagaag gcgaaacgtt
     7081 gcttgatatc ggttgtggct ggggaacatt gatgttcact gctaccaaag agtataatgt
     7141 caaggcaact gggatcacac taagtgaaga acaatacgat ttgattacca aaagaataaa
     7201 agaagaacat ttagaagata aatgccgtgt attattaatg gattaccgcg aactaaaagg
     7261 cgaaacgttt gatcatatca caagtgtagg tatgttcgaa catgtaggtt ctgaaaatct
     7321 tgaaggttat ttcaaagtgg taaaagattt attgaaacca aaaggaacag ctttgatcca
     7381 tggaatcagc cgacaacaag gcggtgcgac aaatgcttgg atcaataaat atattttccc
     7441 tggcggttat gtccctggtg ttactgaatt agttgataat attacaaaaa acgatttgca
     7501 actgattgat ttggaaagct tacgtcgtga ctaccaattg acattagaac attggacaaa
     7561 gaattttcat caagtccaag atcaagtcac gaaagaaatg ggtgattcct tctatcgaat
     7621 gtgggatcta tatttacaag cttgtgcagc ttcatttgaa tcaagtaata tcgatgtgat
     7681 tcaatatttg cttgttcaac ctggaaacaa tgacatccca atgcatcgtg cataattgag
     7741 gcaaaagtac tgtttaaaga ctatttaaaa agaagctaag ttttatgatg ctccagaagt
     7801 gaactttttt gtctaacttc taggattgtc tctaaagctt agtttctttt tctttatatt
     7861 ttcataataa aagtttggtt ctttaatttt taaacatgac agaaaatttt ttcttcgtta
     7921 tacttgtaat agaatactat tttataacaa aggggatcga atcaatgaaa aaaactgtta
     7981 tttatactag tttatttgca gctttgtttt tagctgcttg tcaatcaaat accaatcaag
     8041 gcacatctgg gaatacgtct tccagtagcg aacagcgctc ttcacaggta tcggactcct
     8101 caacaaaagc aagcacatct tcgtctagcc agacaaaaag ttctagtgaa gcaagtactc
     8161 agtcagatat caaagtgtct gcagctcgtg cgatcgaatt gttccaagat aaatacccag
     8221 atactgcaat tactagtttg gaattagata gtgattgggg atcttacttc tacaagatag
     8281 aaggtgtcga tgatcaaaaa gaatacgaag caagaattga tgctcaaaat gaaaaaatgg
     8341 agacagagaa tccagaaact ctagatcgag atgaacaaaa tggtcaaaag aaaaaagaag
     8401 atggtctgga tgttgataaa ttgatcacga ttgaggaagc agcaaaaatc gccgtcgaca
     8461 aagtaggaag cggtacggca acagattggg atttggataa agatttaggt actacttatt
     8521 gggaagtcaa agtaaaagac ggcaatcaaa gtacatcagt caagatcaat agccaaacag
     8581 gcgaagtact gtcaactgaa caagatgatt aagaatttct tcggaaaaca agagttgatt
     8641 tttcttttag tcatgataca ctagacaaaa taacttgttt gaaggagcga tttacttgag
     8701 tttagaaacg acctttgcca atcatatctt tgccaatcct ttgatgaatg catctggtgt
     8761 ccactgcatg actacccagg aattagatga actggctcat tcagaagcag gagcatttat
     8821 cactaagagc tgtacgatca atgaacgaaa aggaaatccc gaaccacgct attttgatgt
     8881 tcctttaggg agtatcaatt ctatgggact tccaaactta ggtttttctt attatctaga
     8941 gtatgctctt gcgtatgaaa aagtgcagga aaaccaaaat caaccgttat ttttttccat
     9001 tgccgggatg agtgtccagg aaaacttgga aatgcttgag aaaatagaaa aaagtgggtt
     9061 taatgggatc actgaattaa atttatcttg tcccaatgtg cctggaaaac cacaactagc
     9121 ttacgatttt gaggccactt atgaaacact gaaagaagta ttcagcatct tttctaagcc
     9181 gctaggaatc aaattgcctc cttattttga ttttgctcat tttgatcaga tggctgatat
     9241 cttgaatcag tttccattga cctatgtcaa tgctatcaac agtgtgggca atggtttgta
     9301 tatcgataca gaacaagaag cagtagtcat caaaccaaaa gaagggttcg gcggcattgg
     9361 cggagagtat atcaagccga ctgctttggc gaatgttcgc gctttttata cacgtttgaa
     9421 accagaaatc caaatcattg gtacaggtgg gattcggaca ggacaagatg catttgaaca
     9481 tctgctatgt ggcgcaagca tgttacagat tggtaccgag cttcataaag aagggccgga
     9541 aattttttct agaatcataa aagaattaac gcagattatg tcagaaaaag gatatacgtc
     9601 aattgacgaa tttaaaggca aattacgcac catttcatag caaagagacg aaggtcatga
     9661 ttgatcttcg tcttttttta taaaaaacac tcgtctgttc attcctgtgc aagcgtactc
     9721 attgtatgtt agacgaactt gtgggaaaat aacagaggca aaaaggagga taatatgaat
     9781 gatgcaacag aattagcaaa agagcttaaa gaaaaagaat ttagttttca agaactagtt
     9841 acggatatac agaaaaaaat aaagaagcaa aatcatgaat tgaatgcgtt tgtcgcgctt
     9901 gaaccattcg agagtaattc ccacgagcta ttgattcccc agtcagaaaa agggccattg
     9961 gctggtatcc catttccttt aaaaatgctc ggtcaagaaa aaaagggatg gctagctact
    10021 tcaggatctc gtttatttga aacacaccga gcttctcata catctaatta tgtgcggcaa
    10081 gcagaagcga taggtctagt tccttttgga caaaccaatg cgccagagtt tggtttcaaa
    10141 aatattacag acccagtcat ctatggccca gcaagaaacc cttggaacct tgaatgtaca
    10201 ccgggcggat caagtggagg agctgctgct gcagtttcat caggaatcgt tcctttagct
    10261 ggtgctagtg atggcggtgg ttctattaga atacccgctt cgttttgcgg attgattggg
    10321 ctgaaacctt cgcgagggac gatgccagtt ggtccatatg cttggagagg atggcaagga
    10381 gctgctattg atttcggctt gacagtttct atgagagaca cggaggcttt attttatggg
    10441 atgagaagta tccattccgg tgcgccatat caagtatcgc cagttgagtg gcaaacacat
    10501 ccaagaaaaa aacggttgaa gatagctttt tgtgttgatt caccgatcca ctcacagatt
    10561 agtgaagagg cagtacttgc tgtaaaaaaa gctgtagatt tccttggaaa agaagggcat
    10621 gatttgacag agattcctta cccactagat ggtcgtaaac tgatcacgtc ttattatcag
    10681 atgaatggcg cagaaacagc agcaatgatc cgctcgattg aaacaggcat ccagcgagct
    10741 gtcagaaaag aagaacttga acccatttct tggactttgt tccaatatgg tcagaagctc
    10801 tctgccgcta cttacatcga ttctctgcat gtatgggatg aagcagcaat tgtcatggaa
    10861 aacctacatc aagaatacga tctattcctt tcaccaacga ctgcatttac cgcccctaaa
    10921 atcagcgaag atttgcaaag tgatgcgata agagcacaga tggaacacat cagtgattgt
    10981 tctgaagtag aaggtttaga cgttgtttct tccatgtttg aggagagctt gaagatcaca
    11041 ccttatacac agttggctaa tctgactgga caaccagcaa tcagcttgcc tactcatttg
    11101 acaaaagaaa acatgcctct aggaatccaa tttatggctg ccagaggaag agaagatttg
    11161 ctatttcaaa tcggctatct atttgaagca aatcatcagt tccatttacc aaatccatgg
    11221 aaatagcaga aacaaggaga agaagaatga agaaaaaaag attgtttgct ctaataacta
    11281 gtgccttttt tattttaagc gcttgcggta cagctgccgc taatcaggaa gataacagct
    11341 ggagtaatgt agaaaaaaag aaagaattag tagtagcgac ttctggcaca ctgtttcccg
    11401 catcttatta taatgatcaa aatgaattag ttggttatga tgtagatttg gcaaaagagg
    11461 tggctaaacg gttaaatgtc aaaatctcct ttaaagaata caacgtggat ggacaaatca
    11521 cttctgtttc aaaaagagaa tcagattttg ctgcgaacga ttttggtatc acaaaagaaa
    11581 gagaaaaaaa attctccctt tcagagactt tcaaatattc atttgacagt atgatcgtac
    11641 gaaaaaaaga tgattcagga atccactcac ttgaagatct taaagggaaa aaagcagctg
    11701 gcgaacccaa tactagctat atgcgtttag cggaaaaaca cggagctaaa ttagtcacat
    11761 atgacaatgc cacgaatgat cagtatttaa gcgatgtagc aaatggtcga acagatgtta
    11821 ttctaaatga ttattatctg cagaaaatgg ccgtatctgc tttaccagat atccctgtaa
    11881 aaatactgga gaacgtttat ttcaatgaaa acgaaagtgg ttttttattg aaagaaggaa
    11941 atgatgctct gaaaaagaaa atcgatggcg tattaaaaga gatgaaagaa gatgggacga
    12001 caaagaaaat atctgaaaaa tattttcaaa ctgatgtttc agtcaaaccg aaagaaacga
    12061 tggctgagtc ggtgagtgag tgatgtactt tcctctaatt gatttttccc tcatgtggac
    12121 ttcacttcct ttcgtactgc aaggcttggt atacacatta gggattggct tcgtgtcgtt
    12181 tcttttagga aatctggtag ggttgctttt gacagtttta ggtcttttgg attggctgcc
    12241 tctgaatgta tttattcgtt tttatttatc gttctttaga ggcattcccg cactagtcct
    12301 gctgtttctg ttatattttg ggttacctta tcaattaagt gccttaacgg cttcagtcat
    12361 ctgctttacg attaccagca gtgcatttat tggtgaaatc tatcgaggat cactagcagg
    12421 cgtttcttca ggtcagtggg acgctggttt agcttctggt ttttctttct ttggggtatt
    12481 gaaatatatc gttttgccgc aagcttttcg aatctcagta ccggcactca gtaacgtagc
    12541 tatggatcta gtgaaaggta cttcgttagc agcaacaatc acagtgccag aaatatttca
    12601 aaaagcaaag atcataggcg gtcggacatt cgattatttt tctctctata ttttagttgc
    12661 actgatttat tgggtcattt gtatcgggat cgaaaaagtg caacagtatt tagaaaaacg
    12721 ttctatgcat cagtcaatct gaaaaataga aatggtgcta gcgtggctgg caccatttct
    12781 attttttgtt tcttgtatat tctgcctagt attttaaaac catttcatgt aaaatgtaaa
    12841 tcgaaaatat gttcggaggt agaaaacatg aagaccccgc taaccatcga aatagaatcc
    12901 tcgttatacc aatattgcat cgagcaaggc ggcttggttg tagaagaagt cacgatgcct
    12961 gatgaccaag gaattgtaga tacgcttagc tgcttgacaa aatttgatgg aagccgagaa
    13021 tggcgatgct atgagctgaa agtgacaaaa gcagattttc gctctacagc caaactgtca
    13081 tttgttggac attataatta ttttgtttta ccaagtaaac tatatgaaga agtaaaaact
    13141 gaaatcccta caggaatagg tgttttagtg tatcgtccgt acacggttga agaggagatg
    13201 cctgcctctg gtacatttct gattgcgaaa aaagcagcaa agaaagagct tgctgtaccg
    13261 gaagaagctt tgacaaaccg cttcatggct tctttattca gggaagtaag aaaagcaaag
    13321 caaatggagc gaggcgtaaa atattttcca acagatcaat tgtacaaaga attgaaaaga
    13381 cgttcagaaa atcaagatcc attttctaac gaacgatatt atgaacggtt tttagaggaa
    13441 atagctagtc aggcaatcaa tgagttgcaa gaagaagtta tcgcgcttca gcatgattat
    13501 gaatatttga ggcaacaaca gcagatccgt cggttgccta cagagccatt ggagtgaaaa
    13561 atatgtacta tccttattta agaggaaaac aatttgacct attagcatta aaagaagcac
    13621 tgtcgcgagg attgctctcc aataaaatcc aaccagtgat cgaaccagta cgtgattccg
    13681 ctacgcttaa aaatgtgatc gaattatttc aaaaaaagca ccatcgaatc gctgtgatcc
    13741 aaaatcccca agtaggacaa ttcaaattat tcgatcagca tgtgcacagt tggacagtca
    13801 aagaaaatag ctctgtcgtc cctgcacaga tcttaacgcc agaaaatctc agtgaagtac
    13861 tggattcacc tccagcgttt cttgttttcg atggacagca ctacccaaaa gatacagagg
    13921 tgtggaaaca gttggcagga gttgattcga aatttttgat accagatact agtcgctttc
    13981 gcatctggct gcccgaaaac aaaattgtga tccgtgactc ttttcaaacg agaaagcatg
    14041 ttgaaagtta tgcagataaa acagatgact tttttagtga tgactatctt tttttccacg
    14101 cagacggata tattggattt tctgatttca cgatcgaagg tagccgttat ttcgataaag
    14161 ggttccctag ccgagcgctt gctatccatc taacgtatat tgatgcttac ggcaatatac
    14221 gcgtgaaaca ttttgtctct gacagtaacg actctgctaa agaccaagca ttgaagtttc
    14281 ttgaagcagg agataaaatg aaaaaatgga tcatgcgtca ccatcatcaa ctcttgatta
    14341 cttcaggaat gattgaatta ttggctcttt accagcaaca aaaattccct ggactgggag
    14401 tgttgaaaaa gtggtcactt atgcatcatt tggaacttat tagtcacctg ctagatcatc
    14461 caaaagattg gcttaaatat tattcaaaag ttcaggaact atatgaagtg atccaatgat
    14521 tagataatgt aaatgaaaaa ggaatagaaa agaggaaact ggatgtatat tcggcaaaca
    14581 aggaaagaag aagtagaaga agtggtagaa atcattaatg ccgcagcgga tttcattgct
    14641 tcgcaaggct ctcctcaatg gcaaaacggg cagaaaccaa caaaagaaac gattttgaac
    14701 gatattgaaa gaaaagaaag ctatgtatta atagtggaag atcaaattgc tggaacagct
    14761 gcattagtct caagcgtgga tcccgtttac acaaaaatag atggtagttg gaaagaatca
    14821 actggtcctt atttatcgat tcatcgtgtc gctttagcag aaagtactcg aggaaaaaaa
    14881 ctagcaaaac cgttcttaga acatttgttg acgattgcag ccagcaaaaa tatccaagat
    14941 atccgtatcg atacttatcc agctaatgaa ccgatggaaa agaccatcta ttctgctgga
    15001 ttcacttatc aagggatgat tgaatttcct tttgaacacg gcgaaagaaa agcatatcaa
    15061 ataatcatca attgactata aaatcatctg agcaaagata aagacattaa cactactgaa
    15121 aaaaacaatc atatgatagc caagaggttg taacagaagt ggccagcttc aaaaaacaag
    15181 aaagaatttc cgaaaatgct tctcaaattt ttgtggaatt ttagcgtatt ttacgaaata
    15241 gctgctttct gaaactccct tcatcgagag gtcgtgacat agcttttgtc acgacctctc
    15301 ggcttatcct acgagtatta ttcgatacat ttatatcaat aatccttttt ttattttatc
    15361 tgcagcttct tggaacgctc catcgtttga cacgactaaa agtgagggga tagctttcaa
    15421 acgtttcaac tgtgctaaat cttctacata aaccgccagt ctggctgaaa tctgttcaga
    15481 tgaatctcca cgttttttca ggcgcgattg caatgtttct ttagagatcg taataaagat
    15541 aggacggact accgtcccga aatactcata taaatgccaa aaaccatttg ctgtcaaaac
    15601 ggcgtaacaa tttcctactg tcagtttctt tttaatttct gctttactgg aaccatattt
    15661 atgttgagca tattggtccc actctgcaaa ctcatttccc ttgatcatct gattgaatgt
    15721 attgtcagaa acaaaataat aatcctcttg atctttttcc ccaggtcttg gtgatcgatt
    15781 cgtgtaagta atgatctttt gttccggctg aaaaatagct tctgcgagtg aagtttttcc
    15841 agaaccagaa ggaccgataa atacatagca ataattcatt gtcatttctc ctttgatgat
    15901 tgaacaagtg aaaaagcttt ggaaaatatt tccaaagctt ttaaaagtaa ctttgctttt
    15961 ttgtatatta taccagcaag ccagtcacaa tagcacttaa aaagctgact aaagtcgctg
    16021 ttagcaaaat tttcaatccg tgttttgcga caagatttcc tttttcttca tttaatccct
    16081 tcatcgcacc agaaatgatc ccgatagaag agaagttggc aaatgaaacg aggaagacag
    16141 atataattgc tgttgtacgc tcagtaaaat ggaaattacc atttgctaat tctgtcatag
    16201 caacaaattc atttgtaacc agtttagtcg ccatgatact accggcatcc actgcttctt
    16261 tccatgggat tccgctgatg aaggcaagag gggcaaagat gtaacctagg atctcttgga
    16321 aagtgatgcc gaatatcccg tggaagatag cattgatcat ggcaatcaaa gcaacaaaac
    16381 cgataagcat agcagcaacc gtgatcgcca catggaaacc atcaagaatg tattctccca
    16441 acatttggaa aaatgtctgt tctttgtttt cttcaatgat cagctcatct tctttttctt
    16501 ctaatacata gggatttaca attgaagcca gaatataacc gccaaataag ttcaaaacaa
    16561 gggcagtgat cacatattta gaatcgatca gtgccatata agatccgacg atcgacatag
    16621 aaactgtaga catagccgat acactcatgg tgaacaaacg tttctcagat aggaagggta
    16681 attccttttt tatggaaata aaaacttccg attgtcctaa aatagcagaa gctactccat
    16741 tataagattc caatttgccc atcccgttga ttttacttaa tcctagacca acagctttca
    16801 taaataatgg aagaatcttg atatagcgta gaataccgat aatagcagaa ataaatacaa
    16861 ttggcatcaa tacggaaaga aagaaaggtg cacttccttt atttgctaca ccggcaaaaa
    16921 caaagtcaac accttgccca gcaaaagcaa gaagatgatc aaacattttt gccaatacag
    16981 aaacaaccgc tgtaccaaaa gttgtacgta ataatacgaa accaagaaca agctgtaaaa
    17041 cgaacatcac aattagtggt ttcaatttga ttgctttttt gttactgctg atcaaaaaag
    17101 caagccctaa tgtgacaaat aaaccaataa tacctaataa ataactcaaa taatcactcc
    17161 tattccaaat tccgttttat tttacctgtt ttgcaaataa aatactaatc tttagtgaaa
    17221 ttttcattac ttttttagag tgaaacgcat tcattttcca ttagaaaata aagcgaacaa
    17281 aataaaaggt ttaaaaagtg taacgtctta gtaaagtcta taaaaaaacg aaactatcga
    17341 ttaagctaat agtttcgttt tcaacattta taagtaaact ttttctattg gtaatataga
    17401 ttttcggaag ggtagacagg tgcgcaggta atatcgattc ctagtttttt caatgtttgt
    17461 tcatcatttt tattgaccat cacagtagag tgggcttgtg ctccctcaag ttcagctagt
    17521 ttatcataag caacttgagc gattggattc gttactgcac tgattgataa agcgatcaag
    17581 acttcattga tgcttagtgc atccaaagag gaatgaagtg tctttgattt caatccttgt
    17641 attgtttcaa gaactaatgg tgacaataaa ggaatgtcat ctgcgatatg ggctaaatgt
    17701 tttactgcat ttaagataac tgccgctgac gcatccatca atgaacttgt acgcccggta
    17761 atgatgactt catctggtaa ttcgattgca atcacagcag aaggatcttt tgtaggactt
    17821 tgcgcttgaa tcttatctgc atagtcatgg gcagggacta ccacgtttcg gtcttcagga
    17881 cgtaaaccga cttcttccat aatcagtttg attcgattaa ctgcttcttc gtcgatcaat
    17941 ccttttttga agtcgcattc tgtttggaaa taacgacgga tgatttcttg tttagaggct
    18001 tcttggacaa cggtatcatc cacgatccca aatcctacac gattcacacc catgtcagta
    18061 ggagattgat aaacagattc tttaccagta attttttcaa taatacgttt gattacagga
    18121 aatgtctcaa catcccgatt atagttcaca gctactttat tgtaggcatc aaagtggaag
    18181 gaatcgatca tattgacatc ttttagatcg actgtggctg cttcataagc aatgttcagc
    18241 ggatgtttca acggaacatt ccatactggg aaagtttcga acttggagta accagctgca
    18301 tgtccttttt ggctttcatg atacagttgg ttcaaggaag tagcgagctt tccacttcct
    18361 gggccaggag ctgtcactac aacgattggt ttagttgttt caatatactc attttttcca
    18421 aaaccatctt ctgagacgat tttttctacg ttgactggat agtcttcgat ttctgagtgt
    18481 ttatagacct tgatgtttcg tctttctagt ttattgataa agactttcgt ggcaggctgt
    18541 ccactatagc gagtgataac gacactgttg attaataagc cataaccacg taattcatcg
    18601 attaaccgca agatatccat atcataagta atcccataat caccacggat cttattacgt
    18661 tcaatatctc cagcatagac gcaaatcagt atttcagctt gatctttcaa tttttgcagc
    18721 aatttgattt tcgcatcttc ttcaaatcct ggaagtacac gtttcgcatg cttgtcgtca
    18781 actagcttcc caccaaattc taaatataat ttgtcatagt ggttcactcg ttccaaaata
    18841 tacgctgact gctcttcaat atatttttct gaatcaaaac caattttttt cactaggttc
    18901 cctccttaag tactaaagca ttttttcatt tttttgagga ttcgtcaact ggaagagcga
    18961 aattcctcaa aaaaacaaag aaaatggttt aaaccaactt gtctagatag ttattcattg
    19021 gtatgatagt ttttgataag gaaggtgcta catgaaaaaa agacagaaaa agaaaaacgc
    19081 atataaacac tatatccgtt cgatttttac cggttatgaa agaatgcttg aagatcccga
    19141 attggaacaa ttgacgttta cttatctaaa cgaagaaacg cagctaactc gtgatgagca
    19201 tcagcgcatt catttcacaa caagagatct gcctagtaaa taaaaaataa gataaaggtc
    19261 atcggattcg attctgtcct atcagatgga aagactagtt gatcgaaaaa aaggctgtac
    19321 caaattttgg tgcagcctgt tttatggagc attgcccgct cttttttata acaatttttt
    19381 acagaaaatg gtactattga agtattaata agtgaaaaac agatgagtaa gaggaggcaa
    19441 gtagtatgaa agagccagat acaaatgcaa attatgagcc agacgaacta gaggagacga
    19501 atgcggatca ggatacagga caagaatcgt cttcttttta cgatatcaaa gaaaaagcaa
    19561 gcatgaatct ttcccaatta ttagaagact tacaggcttt tgaaaaagct gtccgcgaag
    19621 aagatatccc tgagatctac cgtttataca atggccgatt gaatgaagaa ttaaaaagaa
    19681 gctcaaatga aaatcacgag atcgatcaat tgctgatgcg taagatccat gatcgttttt
    19741 tacaggaatt tccttttatg gaacaagtag aaaacatctc gccaacgatg agctattaca
    19801 aaatcggcac ttattaccat gatcggccca cggtcggtat tgatgcaagt ctgccagaaa
    19861 tttttgtttt gcctaagatc gatgaagagt gggagaaata ttcccaaccg gagtcaacgg
    19921 actatgacaa aaaaatcaat gagctagacg caaaggtgat cactgctcag acagaaattg
    19981 aacgtttaga tgaacaaata aaagaaatca atcgacaaat gactgatttg aacgacaata
    20041 aaggattctt gaatcgtaaa aaaatcgagg aagaaattca agaattagag aagaagaagc
    20101 aagtactatc taatgaaaaa ttaggctggc ttccttatat tgagacgcct gaaacaatcc
    20161 agcagcaaaa agaagcattg aagcaagaag caagagcaga ccagcttcgt gcagccatcg
    20221 tagaaaaaga acaaaggcaa atcagacgct atttcggtag caaagaggga ttcggtcaag
    20281 caatccatga attcttgatg aattatcttg gcaatgagaa tcctaataat caatctaatg
    20341 aaggaggttc cgagtatgaa tgaacacgat gaagcagaat ggacaaaaaa tgaagaacaa
    20401 acagaagatc atgaagaaac gaacacttca ttggaagaac aaacaagtaa tcctctggat
    20461 gacacagaag aaatccctat gctagaggaa acaaaaatac acgaaaaaga aaaagtaact
    20521 ccgacgaata cgaatactgc agaaaacacc catgcttacg aaataactga aaatcccggg
    20581 tatttagaag gaaaagagca agatcatcaa gatatcgtca gtttgattga aacagcggaa
    20641 gcagaattag cggatttacg tatgagaaaa gatttgatcg aatcagattt tccacaatta
    20701 ttagaatcat atgatcgttt tatattgaat gaagaaccaa tctccacgat cggaaagaca
    20761 agcctgatcg aatacttcac gtatgaatta ctgaaaccgt tgaatgatat tggtctggaa
    20821 cggtcaaatt cagcttatga cacatggaaa acaagacatt tttcgatcaa ttatacgttg
    20881 aatggacaaa acgaattagt cttttccttt gtattaccga ccatcgatca acgataccaa
    20941 gtggaatcga tgagtctcct aaacgtatca ccagagacaa tggaaatcaa tgtccaagat
    21001 gaccgggtgc tttctttgat ccgacactgg tcagtggatc gagtattctc tgcagggcag
    21061 atcacgatat tcaatcacaa attgaatcaa ttattagccc atgcaagaac acttggtttt
    21121 accgttaatc agacattact agacaatacg aagccacttc gtttgaatct tcagagcgaa
    21181 tttgaattga cgaatgaagt attggatgat atttttatcg tggcaatgaa aaatccatcc
    21241 tacgatatgg aaaagatcaa cgaaactact tatcaagtac gattagataa aggacagtct
    21301 ttaacgataa caacaaacga aaaagatcaa acagtcttgt cgatctcatc tggagactac
    21361 ccacgatctg tcattgattt ctttatcaat tacgaattct tggtcccatt aatggtgaga
    21421 aagtcctgat tggataagtt ggattaccag atgtcattca gataattctg ttccaaagga
    21481 cttgcggcag ttatccagaa taattgtcac aagtcttttc tgtatgtact aaatggacgt
    21541 gaataacttg ctgatgaagg agggatttca ttaggaatgt ccacaaataa aatagcacag
    21601 cttagcttat tgtctgctgc ttgtgtagca ggtaggatcg cttttcaatt tattccgaat
    21661 ttccagccaa tgactgctat ttttttattt atagtacttt acttaagctt aaaagatgcg
    21721 ttaattgtca tgagtctttc tattgcgatc agcagttttt attttggtgt tggaccatgg
    21781 gtcatcggcc aatggatcag ctatactgtt gttctgagtt tgttttcaat cgtctgcttg
    21841 agaaaaacag tgcaaaggaa tctatggtta aagggagtct gtttttttct ggcgggcatg
    21901 gtttacggaa taggtatgac cgtttttgat acgctgttat atcgtttgcc tcaaccttgg
    21961 atctattacc ttcaaggggt gtcgtttgat ttgatgcaca gtataggcaa tgttgtgttc
    22021 tttcttgttt ttctgccagt cgtcaaacgt ttttacaatc attcaggagg aaaaaatgaa
    22081 aaaaataatt tatagtttgc ttgcaatgag tgtcagtata ctcattttga caagttgcag
    22141 tacaacctat acacaatcgg cttccaacca aaaggaggaa gtaaaaacat cgcaaaaagc
    22201 aacaatcacg ttacaagaaa atggtcaaaa cttttcggaa aaagaagtgt tcttcaaaaa
    22261 aggcgatgat ttactgagta ttttgaaacg aaattttgaa gtcaaagaag ataacggctt
    22321 catcacttcg cttgaagggc actcacagga tgagaaaaat caactctatt ggatgtttac
    22381 tgtggacggg aaaagtgcta ctactggtgc caaagagatc aaattgaatg atggacaatc
    22441 ggtcattttc aatttgtcta aactataagt ttcataaaaa actgttaaag ggcgaatatt
    22501 gccataattc agtgagttca gttgatgaaa gaaggaaaat aacatggaaa attttaaaaa
    22561 aagcggaatg ttttccgtaa ttgctgctct aggggctaat attctagttg ctatcagcaa
    22621 atttgtcggc tatgcaatca gtggcagtgc cgccatgcta aacgaaagca tccacagtat
    22681 cgttgattgc agcaatcaga ttttgctgtt attcggtgat aaacaagcca ataaaggaca
    22741 gagcgagttg catcaatttg gtgaaggacg agcaaaatac tttttcagta caatcgtcgc
    22801 aatgatgctt ttcttcggcg gtggggcact tggggtgatg gaagcttttg aaaagttgac
    22861 gcatccatcc catgaagtgg gtaatccgat cattgttata gcaatactgt tatttggttt
    22921 ggtaatcgaa ggaagttcgt tacgcgtggc aatgaaagaa atcaaagaat tgaatactga
    22981 aaaactttcc acgatgcgct ttttgcgcga aagtcgacac agtgaaatac tgattatttt
    23041 tacggaagac ttgtgtgctg taatcggttt ggtcttggct ttagcaggaa caatattgac
    23101 ttatgcaacc gggattgctg catttgatgc gatcagcgga ttgctgatcg gtttcttgct
    23161 gatgggagcc gccattttcc tagcaaaaga attttatagt ctgatcatcg gtgaaagcgt
    23221 gacagcaagc gatttatcaa aaatcaagtt agcttttgaa cgtcctgaga tcagtcggct
    23281 gatcgatata aaaacagttc atttaagtcc aacggagatt ttagttgcag caaaagcaga
    23341 tatcgttggt aacaaagaga atgaagctta ctcggtcatc aatgatattg aaaaaaatat
    23401 gcgtcagtct cttcctgaca agaagatgta tatatacatt gaaacagata aatatgaccc
    23461 aaattattct cgtaaataaa acgtttattc atgaattgaa gcaaaaatga gaaaaatata
    23521 atcttgtttt taaataaaac ggctacaatt tagcgaattt atgttacaat gagtccgctg
    23581 tttatttgtt gtaattaaag gagatatttt aatgaacaaa aagaaaagtg cgccatggct
    23641 tcaagctttg catgcagtga tgccactttg tataagctat ataccagtag gattagcttg
    23701 cggagtattg ttgcaaaaag ttggatttga tcctctctta tcaggactgt tatcgattct
    23761 ggtcttttcc ggtggcgcgc agtttttagt tgcatctatg cttacgacgc aagcatcatt
    23821 tgcaacgaca ttattgatgg ttttcttttt agaattacgc tatacattat taggagcaag
    23881 tcttgccggt tttatgaaaa aagaaaagcg gacgtttttg gctgtctttt ctcaatcact
    23941 gaatgatgaa aactatgcgg tgaactactt aaagttttca actgaccctt cctggaataa
    24001 aagaaaggct ttatatgtca attggttctc aatgactgca tgggccggta gcaatatgat
    24061 cggtaatttt ttcggctcgg tgattcgagt agatgctgac cttgtccatt ttgctttgac
    24121 ggccatgttc attttcatgt ttatcatgca gatgaaaagc gcactactga tctttacagg
    24181 tttattctca ggcgtattag gggtcgtatt catggtatta ttccaaaata ctttcggatt
    24241 gattgcagca acagtcattg cttcatttgc cggatttatg ctggagaagg cattcaaaaa
    24301 agaaaaagct aagaaactaa gagaccgcgg taaagatgtc aatgagccgc tcttcaactt
    24361 cccggaacag gaggccaatc accatgacta aactatattt gctactttta gttgcttgtc
    24421 tgttcatcgt ggcatatatc ccgcgcttgt tcccgatgct ttattttact catcgaaaag
    24481 tgccatcctg gttcagtgac tggatgaaat atgtaccggt ggcattattt gcggcgttag
    24541 cttttaaaga tgttttcatt actcatgaac atctggatat tgcttggaat atcaaaatag
    24601 ctgcaatgat tctagtagca ggcgtggctt acaaaacacg ttcgatggcg ttgtcagttt
    24661 tgacaggact tgcgtctgtc tttttgctgt ctatgcttta aactgtttta ttttattaaa
    24721 aacagagatt gcgacataag ttgttcaaac tgatctatcc gaactgcatt tgcaacagtc
    24781 aattctggat gcaagtttat tcgtagggat aaaaaagatt agtgttggct tatgatgcaa
    24841 gctctttttt attttaggaa ttagagaggg atttgtcctt ctatgatttt ttgctataat
    24901 agggaagatg tttattttat gaaagaatag ttgagggaat ttaaatgaat aaaaaattga
    24961 tgcaaggaac attttggcta acctttgcta atcttctatg taaagtttta ggggtagtct
    25021 atttgattcc ctggctaagt atgatgggga acaatcaaga tggtatgctt gctacgacat
    25081 tgtataatgt tggctatctt ccttatggat tgttcctgat gcttggtaca gtcggatttc
    25141 caaatgcgat tgcaaaaaaa gtagctgtag ccacaaaaga aggagataac gctgcttgtc
    25201 ggctgatttt tagaagtacg atcaatatca tgtttgtcat cggtatcgcc tctgctgcac
    25261 tgatgtattt atttgctcct ttactagccg gaatcagtcc gattgctaac gttaataatg
    25321 ggatactagc tatcagaagt ttatgcccat ctttgattgc tatcccaatt cttagtgcaa
    25381 tgagaggata tttccaagga aaaaatgatc tgcggcctta tggaacttct ttgattatcg
    25441 aacaggctgt gcgagtgatc gttatcttgg ctggtactta ttacttgcgc gtattgactg
    25501 acggaaccat attagaagct gtattgatca gtacagtcgc ttctttcttc ggtgggttag
    25561 ctgcgattat ccatatgtat atcgtcggac gcagaaaaga cttcttcgaa cttaaagatt
    25621 ttttgatttc cagccgttat ttcgaaagag aaaaccgatc tgcctctgtc tctatcattc
    25681 gggaaacact accgtttatt tttgtcggct cagtcattac tatcgttcaa atgatcgacc
    25741 aagtaacgat gaaaccactg cttcactttt tccgtccaga gatcgcagat cagcaactgg
    25801 aattcttatt cagccgtgct tctgtcaatc caaataaatt gacattgatc ctgatctcca
    25861 tggtaggaac agtagctata agcagcttgc caatattaag cacgatgaag aaaaaagatc
    25921 ggatacaaat cgaaaaaaca gtaggagata gtttttcgat tgcgttattg attcttcttc
    25981 cttcattgac tggaatgtct ttattagctg gaccactata cacattgttt tttggctatg
    26041 atcctgaaag tgtcggatat ttccaaatgg ctttgctagc ttctttgttt ttctctttat
    26101 tcacgatcct atctacgatg cttcaatctt tgaatcacca tcgttttgcg atccgattaa
    26161 ctgtagaagc aattatcctg aaagtcatct tccaagtaat cggattagga ttagttggcg
    26221 gatacgggat gagcttatca aatggcttag cattcggtat tgtctttgtt cgcggctatc
    26281 actttatgtg caaagaatac cgaatagcac ctttagcaaa gatcagcaat tttttcttaa
    26341 aaactttccg ctccaccctg attatgcttg cagtatgttt tgccgttttc tttttgctga
    26401 atcagcgatt gtcaatggaa tcaaaaagct atgcaatgat ttattgtgtg gctgtaggaa
    26461 gtattggcgg cttagtattt ttattttctc aattcggaaa aaatgggttt cgaatgttga
    26521 aaaatgttaa acatcatagc agaagcaaag aataggttaa ctaatcgttt tttgctgtca
    26581 cttgaaaaac ggcaactcgt atgattacgc ttgtcgtttt tctattttcc aattttagtt
    26641 tcatatctaa tcttacttat gatatagtta taaggtctgg aaaaattctt tgaaacgagg
    26701 aaattaaaca catgaaactt gcagtagtta cagatagttc ggcatatctg ccggaacgta
    26761 tcaagaacca tcccgactta ttcgttattc caatcccttt gattatggat gggaaaattt
    26821 ataacgaagg aatcgatatc gaagcggatg aatattatgg acttttaaaa aacagtaaag
    26881 attttcctac tacttcacaa cctgtcgtag gggaagtttt gggtttatat gaggaattga
    26941 aagagaaagg gtatgacacg attttaagta tccatctttc ttcagggatt tctggctttg
    27001 tcaacacatt atttgcgatg aaagatgaca tcagcggagt aacggtcatt ccttatgact
    27061 ctaagatcac tagtatgccg atgggacaca tggtagaagc tgccttagac ttaaatgatg
    27121 aaggtcagtc ccttgatgaa atacttgcac atatcgatcg aatccgagat aatacctacg
    27181 cttatctgat tgtagatgat ttgaacaatt tagtacgagg aggacgtttg acaaatggtg
    27241 cagcgctgat tggcagctta ttaaaaatca aaccgatcct gacattttct gaagggaaaa
    27301 ttgttttatt cgaaaaaatc cgttcaagta aaaaagcatt tgctcgagct gaagaaatta
    27361 ttggtagaag aaataacgaa atacaaccgc cagtcaaact ttacgtgata catgcaaata
    27421 atttagaagt agcgattgcg gagaaagaga aattgcagaa aaaatatcca aatgcagaaa
    27481 tcgaaattgg tcatttcgga ccagtcattg gtacacattt aggtgaaaaa gccatcggca
    27541 ttgccatttc agcgcaataa ttccttttat tcaaaaaaca taccaaaaat attccaacat
    27601 catcttggac tttctacatg ttactaatga gcgtgtaaaa gaacgagatg gtgtttttat
    27661 ttctatcaat gaagctcttt ttctttgcaa tcctcacttc aatcctctat aatgtcgcat
    27721 atagtttagt aaatgagtaa actactaatt tacttattta ctaaaaataa aaggatgagg
    27781 agttaaaata atggaaatac caacaaattt aaaacataaa ccagtaatcg ttgtagaaga
    27841 ctatgataaa gttgatggaa gaaatgcatt aaatacggat gcaaaagggc tttcactggg
    27901 ccttgctcag tggaatgatc gtggaaaagt cgatatctca ggcaaggtat ggcgacatac
    27961 tggagaaaaa tggtcacgac agtcggaaga attaccaatc acacgtattt tagatttagc
    28021 gatcttagct gcacaaggaa gtttatactt ccaagatgct tatcgttatg aaaaatttta
    28081 tgatccagaa aatccagtcg tagacatcat tggattacaa gggaaccgaa tgacggtaga
    28141 agtagatacc aaaaatccaa agatcgatga agacatcatt ttgtattacg atacactaca
    28201 aaaagacgga gaactgattg gggaacgatt ccgtatttta aaacgtcttt tagatgagct
    28261 aggatattaa tagacagaga tgatcaaaag gggaagagaa gcatggagaa tttctcacta
    28321 acagaaaacc gaaccttttc acggctagaa aagcaaatga tctggaagaa accgaaaagc
    28381 catcggacaa gtgcagaaga atggcggatc gcctccgaaa tcaaagggaa ttggcaagat
    28441 cctgaaatga aaatcagtaa cgtacttttg gaaggagatg ccgggtcggg gaagacacaa
    28501 ttagccaaag cactatctgc tgatctgcaa cttccctata caaaagtgac ctgttttgca
    28561 gatatggaca aatcagatgt tttcggagcc ttattacctg tagtagattc taataaggaa
    28621 caagaccaag aattactaga agctatttac caaacagata cacttgaagc tgtactgaca
    28681 ctgatccaga accattacgg cattgatcct ttttctgcta aagaaaaatt agcagagcta
    28741 gttcaaagga tcgaagctga ttatccagat gcaatccatt acagctatta cccttctgaa
    28801 atcgttcgag cgattgaaaa aggatattta ttagagattc aagagccgac tgtcatccga
    28861 gatgcctctg ttcttgtggc acttaactca gcgctcgaac caaatgggat gttgaattta
    28921 ccgacaggaa tcattcgtcg ccatccagat tgcgtcattg tgatcactac aaatcgaaat
    28981 taccaaggaa atcgcccatt aaatgaatct ttaagagatc ggatgcaaca tgcggaaaaa
    29041 atggatcttc ctgccttaga agtcatggca gaacgtgcga tggcgaaaac tatgatccaa
    29101 aaacaagaac ttctcttaaa gatggcagag attatccgtt tgttggatga aactgcaaaa
    29161 gctaacgcca tcaaaggtgt agcaggaatg cgttcttatt tttattgggc aaatacctat
    29221 aagcaaggac aagatttact ccagtcgatt tatccaaaag ttttgtataa attatccact
    29281 gattcagatg aattggcaat tcttgaacaa gctttgtctg acagtggatt gctactggaa
    29341 cttcaggaca tattgagaaa agaaaaatgg ggtcatcctc aatctgagca tacaaaagga
    29401 agaaccatta gcgccgaaga agcaaatgaa cgaaacatca ctgaaaatgc tgaagaaatt
    29461 ctgcgcttag atgaaaagaa atcgttgtct gctgaagaac caaatgaggg agaagagaaa
    29521 caagaagaaa caatagaaaa aaacgagatt cctcctcaaa tgcaaaaaga acgcagtagc
    29581 gatatcgaag gaaaaaatca aaaagaacaa caaacaggag atgattctca agaaatgtct
    29641 gcttctgaca tggaagcaca tgataaggaa atcaagaagc aactgaataa agaagcgcga
    29701 caaatcatga aggaaacgat tcatgaaaaa gaaggtctca tcgttcaccg accagctttc
    29761 caaggaaaaa cgccggaagc acgtgagcta cacatgcaag taatgccaat agtagaatca
    29821 cttagccggc aaattttaga gttactggat aatgaacaaa cagagacgta ccaaaaagga
    29881 aaatacgaag gtcagcggtt caatgcaagc aaagtagcat atggtgattt gagaaatttt
    29941 gacaaaaaga acccgccaca tgagcaacct tctttagcgg tagctgtacg gatcgatgaa
    30001 tctgggtcaa tgatacggga tgatcggatc gaagcggcaa aaaaagcagc gattgccatt
    30061 gccgaatttt ctaagaaagt cgatatccca ttgttgattt acggagatac agcagaccgt
    30121 tcgtcaagag aaaagacttc tttgttttct tataaagaat ttgaagacgg atttcaatgg
    30181 ttaaatgaaa aattagtcac tatgaaacca aggcaaaaca atcgtgatgg tgctgcactt
    30241 cgtttagcag cagaaaaatt aaacagacaa tccgcaacaa ccaaactgtt gcttaatatt
    30301 agtgacggtc agccaaaagc gttgccggat tatacaggca aaaaagcaaa agaagatatc
    30361 cagtctgttt tgaaagaata tgaacgtcaa ggaatcctat ttgtctccgc agctattggc
    30421 caagacaaag aagaaatcaa gtcgatctac ggtgaaagtc gttttgtaga tattactgac
    30481 ttgaatgaat ttcccaagca aatgattcaa ctgattgccc gctatctatg ataaaataaa
    30541 gctcaacgaa cgcacttagc agattcgttg agcttttcgt ttctagttac cggtaacaag
    30601 gatacttcta aaatagaatc ggttataatc aagagggacc gttaaaggag tgaaacgata
    30661 tgatacaaga acaaaaatgg tggaaagaag cagtaggcta tcaaatctat cctgctagtt
    30721 tcaaagatag caatggcgat ggtcaaggag acatcaatgg gatccgtgaa aaacttaatt
    30781 atttgaaaga tcttggtatc ggctttatct ggatcaatcc gatctatcaa tctccatttg
    30841 tcgataatgg ttatgacgta agtgactatc aagatataga agagagattc ggaacgatgg
    30901 aagattttga tttattgcta aaagaagcac atgaattagg gatcaaagtg attatggatc
    30961 ttgtcatcaa ccatagttcg gatcagcatc aatggtttga agaatcgaaa aaatctaaag
    31021 aaagcccgta tcgcgattat tacatttggg tcgacggggt agatggcaaa gaaccgaata
    31081 attggacatc gattttcggc ggttctgctt gggagtattc tcatgaaact ggacagtatt
    31141 atctgcatgt ttttgcaaaa gaacaaccag acttaaattg ggaaagcgag aaattgaaag
    31201 aagaactatt caatatgatc cgatggtggt tggataaagg gatagatgga tttcgtttag
    31261 atgcgatttc tcatgtaaaa aaagatgaat attcagtaaa agccacagag aaccctttct
    31321 caccctttca aaatgtctca ggaatcgaag aacatttgac cgatttgaaa catgtttttg
    31381 aagagtacga tatcatgact gtcggagaag caagtggtgt cactgcagaa gaaggaccac
    31441 aatgggtagg gaaagacggt tatttcgata tgatattcga atttgatcat atccatatct
    31501 ggcagcaaga aaaagaaggg caattagatg tccttaaatt gaaacttgca ttaagcgctt
    31561 ggcaaacttc attggatggt atcggatgga acgctttata tatggaaaac catgatgttc
    31621 ctcgtgccgt ttcagtgttt ggagatactc gtcccgattt ttgggctatg tctgcaaaag
    31681 caatcgctat gatgtatttc tttttgcaag gtacgccatt tatttatcaa ggacaggaaa
    31741 tcggaatgac gaatatgccc tttgaatcga tcgatcaagt tgatgcagta gattcgaaaa
    31801 gactttataa aaggctgctt gcggaaggta agacaagaga agaagcattg gatatcattc
    31861 gtgaaacaac gagagacaac agcaggacac ccatgcaatg gacttcggaa caatatgctg
    31921 gtttttctac acatgaacct tggctgatca ctaatccaaa taccaaaacg atcaatgtag
    31981 aacaacaaga atatgaacca gagtcggtcc tgcaattcta taagaacatg atccgcatta
    32041 gacaaaccaa taaaggtctg atatacggtt cttataaaga atatcttcat gaacatccac
    32101 aactttatgt ctatgaaaga tatttagaag atgaacaata tcttattatg gtaaacttaa
    32161 cagaatcact tgctgactat gaacttccaa aagaagcaga tcagtcctgg acattactct
    32221 tgtcaaattc ctctagcgga gaatttgaag ctaaaggcat actagcacct tatgaagctc
    32281 ggttatataa aacaaacaag taaaacttcc tcgttaaagt tcattagttg gactttgcga
    32341 ggaagttttt cagattgctc tgtcaattac tcatttcaat aattcgctct aggaccaccg
    32401 atatatttag gacgagagcg aagggctgtc acgtgagctt gtccaagggt tttcaaacga
    32461 ggtctgacag gtacttggac atgtttgata tgcataccga ttgatgtgtc accgatatcg
    32521 ataccggctt gtccaactac gtgttccact tcgacaggat cattgaactg gtcaaaagca
    32581 gcaacagaac aagcacctcc agcatgtagt gcaggaacaa cagagacaat ttcgaaattt
    32641 tttgcttctg ccactgttcg ttctactact aatgctcggt tcaaatgttc acaaccttgg
    32701 acagctagcg caatttcttt aggatccaac aactctttta acgtacggat gatccattga
    32761 ccaacttccg cactggaatt ttttccaata tgtcctccaa cgacttcgct tgtgctgcat
    32821 cctaaaacaa aaagatcacc ttttttcaag tgtgcctcag ccaatatgtc attaactatt
    32881 tcagtcaatt ggtcttttaa ttctttttct gacaacttca ttttctaaaa ccttcttttt
    32941 caattaatat tgcttccgtg cttgaatacg ttgaagactt gcagttatag gaaaggcaag
    33001 tcccattcca atcagatttt ggaagatgtt tcctggtata gaagccactc cagccggcca
    33061 atcatataaa atccaaccgg cgataccata gccgatgatc ataactaagc ttcctaataa
    33121 aagccctaat ccccacatac gagtagaaga tttgctgaaa gaaccagcaa catatccttg
    33181 taacccgtgg atcactaatg aaaaaactgc ccactgcgga tatcctgaaa tcaaatcgat
    33241 caatagacca ctggaagcac caacaactaa tccacccgtt ggaccataaa gaaaagcagc
    33301 ggtatagatc ccggcctcgc ataatgtcac aaatccattc gtagccggta cagggatcaa
    33361 aattgttaat gaaagggcaa ctgtcaacgc aatcagcata gcatagatcg ttaattgctt
    33421 agttttcatt tctcattcct cctttttgaa taccgccaga ccagacactt ccggtatgat
    33481 cgttcatcag cacgccatta gaaatacaat gggcaacaaa ttttttactt tctgctactg
    33541 ctttggtaaa atctgcccct aacacaagat tcgctgttat tgcagaagaa aaggcacaac
    33601 cggccccgtt tactgttgta gtgtcgattt ttttatgaga aaatacctca taatgatcaa
    33661 ttgaatagag aagatccaca gcttcatctc cagccatcct tgtgccgcct ttgatcacaa
    33721 tgttttttgt tcctgaagca gtgagttctt tagcgagatg gatcatttct gttaacgaag
    33781 agggaagagc ttgaccagaa agtaaagcag cttctgccaa attaggcgta atcatcgtaa
    33841 caagtggaaa aagttcttcg atgagctgcg aaatatacaa ttgattgatc acagcttcag
    33901 tttctttgaa tgccaaaaca gggtctaaaa tgattgggat attttgtttt gtttttatga
    33961 agtctcgaac aaccatgatt gcttcacttg aattcaataa cccaattttg ataccatcta
    34021 atgaagtcat tttatcaatc gaaactaact gtcgtttaag caattccaaa gatatagatt
    34081 ccagcataaa tcgctcatta atatctagtg cccctataga agtcaaggcg cttagtccga
    34141 atagaccaaa attctcaaaa gtttttaaat ctgtttggat tcctccacca gcaaatggat
    34201 cagaaccgcc aattgtcaag attcttttca taacattttc ctccatgaat aagagtataa
    34261 cgaaattttc aaaaaagaaa aacagccaat tggcatattt ttatctcatc caatttaaaa
    34321 aaacaaaaag aaaagaaaga ccaaaatgga tctttctttc cttaaatagt taggactttt
    34381 gtgattttaa ttctttctcg atttgaagcc gttgcacttt cattgtagct gttcgcggga
    34441 ttgcatcaaa atcacggatg atagggacgt tcaagcgagg aagttcatgg acttgctccc
    34501 accatcgatt ccaatccatt tctttatcag gagctaaagc aataatcggt tgtggagaat
    34561 gatttttatc ccttacaatc actacttctg ccaaaaaatc taacgaatct aataaaaagt
    34621 cttcaatagc taatgtacta ttgatcgttt cgatcaaatc cacttgccga tctttcaaaa
    34681 ataggtggcc atgcttatcc ataaaaccgt aatctccgct atcccaccaa tcgccataaa
    34741 cattttcctg gaaccgtgca tcttccttgt aataagtcaa agcccgtcct ttagacagta
    34801 attgtatatg accatctgtg ttttcaggta ggacattccc aactgaatct gtaatccgag
    34861 cgcttgtcat gtcttccagt ccaacgccca tatctcttgc atcacttgtt ttcaaactct
    34921 ctagtgtatg agccttaaga atcattggtc cgcattcact ttggccatat acttgaagaa
    34981 ataccgcatc ctgtgccatc gacgttcgca aaaatgtctt cattgtctgg ttgtttatag
    35041 catcaaaagt ggagtgatag tatcggatac ccgaaaaagc ttctggatgc tccttagcag
    35101 taaaacgcca ctgaacaaag ttattcggat gggtctctag tgcaattggc cggtgagctt
    35161 ccaacatatg aacaactttt gaactttgtg cgtttgctaa aggcatcata ggaaatccca
    35221 tggacatcaa agaagagata ccaatattga atctggaatg cactggagag atgtgaaaag
    35281 cgattaattt cttttccgaa atttttgtga aaactgtttt ttgccatttc gtccgccatc
    35341 ccatagaatg agcagaatga caaataagtt tagggatacc agttgtacca gaagtatggg
    35401 tcatataaga aatttcattt ttgtctaaaa atgattgaga aacagacaaa gcaggttgtt
    35461 ccattaaata aagaatagga a
//
LOCUS       DADVXK010000015        34960 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.015, whole genome shotgun sequence.
ACCESSION   DADVXK010000015 DADVXK010000000
VERSION     DADVXK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.015"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="KB909_000740"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="KB909_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBB6836797.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="KB909_000741"
     CDS             complement(2020..2922)
                     /locus_tag="KB909_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6836798.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="KB909_000742"
     CDS             complement(2919..3611)
                     /locus_tag="KB909_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBB6836799.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="KB909_000743"
     CDS             complement(3654..4295)
                     /locus_tag="KB909_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6836800.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="KB909_000744"
     CDS             complement(4333..4647)
                     /locus_tag="KB909_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836801.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="KB909_000745"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="KB909_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="KB909_000746"
     CDS             complement(5984..6916)
                     /locus_tag="KB909_000746"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBB6836802.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="KB909_000747"
     CDS             complement(6913..7689)
                     /locus_tag="KB909_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBB6836803.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB909_000748"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB909_000748"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBB6836804.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB909_000749"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB909_000749"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBB6836805.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="KB909_000750"
     CDS             complement(12014..13294)
                     /locus_tag="KB909_000750"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBB6836806.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="KB909_000751"
     CDS             complement(13313..14239)
                     /locus_tag="KB909_000751"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBB6836807.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="KB909_000752"
     CDS             complement(14252..15535)
                     /locus_tag="KB909_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBB6836808.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB909_000753"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB909_000753"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBB6836809.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="KB909_000754"
     CDS             complement(16323..17234)
                     /locus_tag="KB909_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6836810.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="KB909_000755"
     CDS             complement(17231..17695)
                     /locus_tag="KB909_000755"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBB6836811.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="KB909_000756"
     CDS             complement(17700..18398)
                     /locus_tag="KB909_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6836812.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="KB909_000757"
     CDS             complement(18385..18771)
                     /locus_tag="KB909_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836813.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="KB909_000758"
     CDS             complement(18918..20588)
                     /locus_tag="KB909_000758"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBB6836814.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="KB909_000759"
     CDS             20771..21004
                     /locus_tag="KB909_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBB6836815.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="KB909_000760"
     CDS             complement(21103..21534)
                     /locus_tag="KB909_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBB6836816.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="KB909_000761"
     CDS             21613..22026
                     /locus_tag="KB909_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBB6836817.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="KB909_000762"
     CDS             complement(22064..23212)
                     /locus_tag="KB909_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6836818.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="KB909_000763"
     CDS             complement(23334..23930)
                     /locus_tag="KB909_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6836819.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB909_000764"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB909_000764"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBB6836820.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="KB909_000765"
     CDS             27160..27591
                     /locus_tag="KB909_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6836821.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="KB909_000766"
     CDS             complement(27636..28985)
                     /locus_tag="KB909_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6836822.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="KB909_000767"
     CDS             complement(29055..30218)
                     /locus_tag="KB909_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6836823.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="KB909_000768"
     CDS             30347..30670
                     /locus_tag="KB909_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836824.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="KB909_000769"
     CDS             complement(30853..32202)
                     /locus_tag="KB909_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6836825.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="KB909_000770"
     CDS             complement(32271..33224)
                     /locus_tag="KB909_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBB6836826.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="KB909_000771"
     CDS             complement(33326..34516)
                     /locus_tag="KB909_000771"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBB6836827.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9951 a         7641 c         6120 g        11248 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatataacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa
//
LOCUS       DADVXK010000016        34772 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.016, whole genome shotgun sequence.
ACCESSION   DADVXK010000016 DADVXK010000000
VERSION     DADVXK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.016"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(227..1114)
                     /locus_tag="KB909_000772"
     CDS             complement(227..1114)
                     /locus_tag="KB909_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6836828.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="KB909_000773"
     CDS             complement(1111..1980)
                     /locus_tag="KB909_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836829.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="KB909_000774"
     CDS             complement(2117..3403)
                     /locus_tag="KB909_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6836830.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="KB909_000775"
     CDS             3676..4254
                     /locus_tag="KB909_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6836831.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="KB909_000776"
     CDS             4254..5183
                     /locus_tag="KB909_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6836832.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="KB909_000777"
     CDS             5180..6916
                     /locus_tag="KB909_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6836833.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="KB909_000778"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="KB909_000778"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBB6836834.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="KB909_000779"
     CDS             complement(7812..8321)
                     /locus_tag="KB909_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBB6836835.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="KB909_000780"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="KB909_000780"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBB6836836.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="KB909_000781"
     CDS             complement(9622..10713)
                     /locus_tag="KB909_000781"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBB6836837.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="KB909_000782"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="KB909_000782"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBB6836838.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="KB909_000783"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="KB909_000783"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBB6836839.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="KB909_000784"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="KB909_000784"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBB6836840.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="KB909_000785"
     CDS             complement(14676..15650)
                     /locus_tag="KB909_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBB6836841.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="KB909_000786"
     CDS             complement(15631..17514)
                     /locus_tag="KB909_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBB6836842.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="KB909_000787"
     CDS             complement(17532..19757)
                     /locus_tag="KB909_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6836843.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="KB909_000788"
     CDS             19872..20906
                     /locus_tag="KB909_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6836844.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="KB909_000789"
     CDS             complement(20973..21986)
                     /locus_tag="KB909_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6836845.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="KB909_000790"
     CDS             complement(22064..22252)
                     /locus_tag="KB909_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBB6836846.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="KB909_000791"
     CDS             complement(22692..22820)
                     /locus_tag="KB909_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6836847.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="KB909_000792"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="KB909_000792"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6836848.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="KB909_000793"
     CDS             complement(24307..25362)
                     /locus_tag="KB909_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6836849.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="KB909_000794"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="KB909_000794"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBB6836850.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="KB909_000795"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="KB909_000795"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBB6836851.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="KB909_000796"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="KB909_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBB6836852.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="KB909_000797"
     CDS             complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="KB909_000797"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBB6836853.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="KB909_000798"
     CDS             complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="KB909_000798"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBB6836854.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33124..34683
                     /locus_tag="KB909_000799"
     CDS             33124..34683
                     /locus_tag="KB909_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBB6836855.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9518 a         7495 c         6336 g        11423 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata gtaaaaccaa
    29821 gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt tcatagggca
    29881 aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca atcgaatgac
    29941 atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct agcgcatcat
    30001 actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa gtgtccagat
    30061 ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg gcgttccgag
    30121 gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg acaaatgacc
    30181 gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt aatttgattg
    30241 ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt ccatccccgc
    30301 gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa agtccatcta
    30361 tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca cgttgatcaa
    30421 aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga atatcatgag
    30481 tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga gaatcagacg
    30541 tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct ttatcataaa
    30601 catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat tggttcagtc
    30661 ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca tgttccatca
    30721 tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag acgttttact
    30781 ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct tactcggacg
    30841 actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca gctgttattt
    30901 tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt atagctatat
    30961 gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc ttcgatttcc
    31021 agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg cgtccgtcca
    31081 tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg cgtgatcccc
    31141 acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc tcgagataaa
    31201 ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa tcctttggct
    31261 gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc aatgtcggaa
    31321 acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc agcgtcttct
    31381 tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa ttcctccaag
    31441 ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc tagatatccg
    31501 ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat catctgagtg
    31561 acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc accgatattt
    31621 gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga agcaaaactg
    31681 cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac gatacgctca
    31741 aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat atctttgatt
    31801 tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt tgctttcaac
    31861 agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc aaagtcgccg
    31921 taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa acgggtttcg
    31981 tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt ttctgtccac
    32041 aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc gctaaggatg
    32101 tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg ataatctttt
    32161 tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact ttgatctgca
    32221 tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag cgtatactgt
    32281 gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt ttgataatac
    32341 gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag gtcgtcaaag
    32401 tccatacatt gattatattg aagctctttt tggtaagcag cataacattt tgccgcaatc
    32461 tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag gctgtttttt
    32521 gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc aatgttcagt
    32581 tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat tgtaaagttc
    32641 cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat cgagtgaaaa
    32701 gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg ttctttcatt
    32761 tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt gacttctttt
    32821 tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact tcctgcacct
    32881 gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg ggggttcatc
    32941 ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat caatcttgtt
    33001 aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt tgtttctttt
    33061 tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa gcgaggcgtt
    33121 tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata ttttattcta
    33181 aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg attatctatc
    33241 gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca gccgatttac
    33301 ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta tctggtcaaa
    33361 aatgaaccgg atatcaaggg aagcgggatt ccacaagtag agggacagct tcgcggggaa
    33421 ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt actttcagtt
    33481 ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc atccattgga
    33541 caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt aatttctagc
    33601 ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt actctttgtt
    33661 ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt tgcttcagca
    33721 atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt atatctaggt
    33781 gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg agtacttcta
    33841 ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt ttacaaccga
    33901 ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt gccaattggt
    33961 tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt tggacatgct
    34021 tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt ttccatgatt
    34081 tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt gggggcttta
    34141 atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat ctacatcaag
    34201 gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc accgctgaca
    34261 gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc tttaggattg
    34321 gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat ttacgaatca
    34381 ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc aaggacaact
    34441 tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg agacttcaat
    34501 tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat cttgactcac
    34561 ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga agcaaacttg
    34621 ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa gcaatcattt
    34681 taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt gattctatat
    34741 gattctataa aaaaagaaga ggctgggaaa ac
//
LOCUS       DADVXK010000017        34716 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.017, whole genome shotgun sequence.
ACCESSION   DADVXK010000017 DADVXK010000000
VERSION     DADVXK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.017"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(451..1761)
                     /locus_tag="KB909_000800"
     CDS             complement(451..1761)
                     /locus_tag="KB909_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6836856.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="KB909_000801"
     CDS             complement(1773..3191)
                     /locus_tag="KB909_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6836857.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="KB909_000802"
     CDS             complement(3431..4999)
                     /locus_tag="KB909_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6836858.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="KB909_000803"
     CDS             complement(5003..5413)
                     /locus_tag="KB909_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBB6836859.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="KB909_000804"
     CDS             complement(5410..6333)
                     /locus_tag="KB909_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBB6836860.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="KB909_000805"
     CDS             complement(6330..7208)
                     /locus_tag="KB909_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBB6836861.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="KB909_000806"
     CDS             complement(7195..8532)
                     /locus_tag="KB909_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6836862.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="KB909_000807"
     CDS             complement(8535..9638)
                     /locus_tag="KB909_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6836863.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="KB909_000808"
     CDS             complement(9712..11220)
                     /locus_tag="KB909_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6836864.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="KB909_000809"
     CDS             complement(11186..11878)
                     /locus_tag="KB909_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6836865.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="KB909_000810"
     CDS             complement(11900..12874)
                     /locus_tag="KB909_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836866.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="KB909_000811"
     CDS             13174..14046
                     /locus_tag="KB909_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6836867.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="KB909_000812"
     CDS             complement(14504..16702)
                     /locus_tag="KB909_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836868.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="KB909_000813"
     CDS             16934..17926
                     /locus_tag="KB909_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6836869.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="KB909_000814"
     CDS             17986..19407
                     /locus_tag="KB909_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBB6836870.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="KB909_000815"
     CDS             19400..20899
                     /locus_tag="KB909_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBB6836871.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="KB909_000816"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="KB909_000816"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6836872.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="KB909_000817"
     CDS             22491..23174
                     /locus_tag="KB909_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBB6836873.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="KB909_000818"
     CDS             23176..24012
                     /locus_tag="KB909_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6836874.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="KB909_000819"
     CDS             24023..25777
                     /locus_tag="KB909_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6836875.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="KB909_000820"
     CDS             complement(26053..26394)
                     /locus_tag="KB909_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6836876.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="KB909_000821"
     CDS             complement(26462..28633)
                     /locus_tag="KB909_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6836877.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28802..29701
                     /locus_tag="KB909_000822"
     CDS             28802..29701
                     /locus_tag="KB909_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6836878.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="KB909_000823"
     CDS             complement(29772..30629)
                     /locus_tag="KB909_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6836879.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="KB909_000824"
     CDS             complement(30614..33316)
                     /locus_tag="KB909_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6836880.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="KB909_000825"
     CDS             complement(33329..34618)
                     /locus_tag="KB909_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBB6836881.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
BASE COUNT        10190 a         7174 c         6107 g        11245 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcagggc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagcatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taaaccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttt
//
LOCUS       DADVXK010000018        34661 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.018, whole genome shotgun sequence.
ACCESSION   DADVXK010000018 DADVXK010000000
VERSION     DADVXK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.018"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            591..1280
                     /locus_tag="KB909_000826"
     CDS             591..1280
                     /locus_tag="KB909_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6836882.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="KB909_000827"
     CDS             1267..2475
                     /locus_tag="KB909_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6836883.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="KB909_000828"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="KB909_000828"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBB6836884.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="KB909_000829"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="KB909_000829"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBB6836885.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="KB909_000830"
     CDS             complement(6578..7273)
                     /locus_tag="KB909_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBB6836886.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="KB909_000831"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="KB909_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBB6836887.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="KB909_000832"
     CDS             complement(8472..8663)
                     /locus_tag="KB909_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBB6836888.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="KB909_000833"
     CDS             complement(8684..9574)
                     /locus_tag="KB909_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBB6836889.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="KB909_000834"
     CDS             complement(9561..10328)
                     /locus_tag="KB909_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6836890.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="KB909_000835"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="KB909_000835"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBB6836891.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="KB909_000836"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="KB909_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBB6836892.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="KB909_000837"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="KB909_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBB6836893.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="KB909_000838"
     CDS             14899..15282
                     /locus_tag="KB909_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836894.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="KB909_000839"
     CDS             complement(15450..16208)
                     /locus_tag="KB909_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBB6836895.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="KB909_000840"
     CDS             complement(16226..17044)
                     /locus_tag="KB909_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6836896.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="KB909_000841"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="KB909_000841"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBB6836897.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="KB909_000842"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="KB909_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBB6836898.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="KB909_000843"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="KB909_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBB6836899.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="KB909_000844"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="KB909_000844"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBB6836900.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="KB909_000845"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="KB909_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBB6836901.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="KB909_000846"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="KB909_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBB6836902.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="KB909_000847"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="KB909_000847"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBB6836903.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="KB909_000848"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="KB909_000848"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBB6836904.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="KB909_000849"
     CDS             27086..27385
                     /locus_tag="KB909_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBB6836905.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="KB909_000850"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="KB909_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6836906.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="KB909_000851"
     CDS             27973..28209
                     /locus_tag="KB909_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBB6836907.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="KB909_000852"
     CDS             28352..30325
                     /locus_tag="KB909_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBB6836908.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="KB909_000853"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="KB909_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBB6836909.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="KB909_000854"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="KB909_000854"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBB6836910.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="KB909_000855"
     CDS             33204..34496
                     /locus_tag="KB909_000855"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBB6836911.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10564 a         6734 c         6854 g        10509 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa a
//
LOCUS       DADVXK010000019        33443 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.019, whole genome shotgun sequence.
ACCESSION   DADVXK010000019 DADVXK010000000
VERSION     DADVXK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.019"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            301..1857
                     /gene="rny"
                     /locus_tag="KB909_000856"
     CDS             301..1857
                     /gene="rny"
                     /locus_tag="KB909_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBB6836912.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1936..2742)
                     /gene="proC"
                     /locus_tag="KB909_000857"
     CDS             complement(1936..2742)
                     /gene="proC"
                     /locus_tag="KB909_000857"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBB6836913.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            2883..5456
                     /gene="mprF"
                     /locus_tag="KB909_000858"
     CDS             2883..5456
                     /gene="mprF"
                     /locus_tag="KB909_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6836914.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            5598..6461
                     /locus_tag="KB909_000859"
     CDS             5598..6461
                     /locus_tag="KB909_000859"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBB6836915.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            6706..7644
                     /locus_tag="KB909_000860"
     CDS             6706..7644
                     /locus_tag="KB909_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6836916.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            7667..8347
                     /locus_tag="KB909_000861"
     CDS             7667..8347
                     /locus_tag="KB909_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6836917.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            8320..9144
                     /locus_tag="KB909_000862"
     CDS             8320..9144
                     /locus_tag="KB909_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6836918.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            9311..10129
                     /gene="purR"
                     /locus_tag="KB909_000863"
     CDS             9311..10129
                     /gene="purR"
                     /locus_tag="KB909_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBB6836919.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            10632..12005
                     /gene="glmU"
                     /locus_tag="KB909_000864"
     CDS             10632..12005
                     /gene="glmU"
                     /locus_tag="KB909_000864"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBB6836920.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            12099..13070
                     /locus_tag="KB909_000865"
     CDS             12099..13070
                     /locus_tag="KB909_000865"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6836921.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      13076..13178
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13244..13813
                     /gene="thiT"
                     /locus_tag="KB909_000866"
     CDS             13244..13813
                     /gene="thiT"
                     /locus_tag="KB909_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBB6836922.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(13894..14667)
                     /locus_tag="KB909_000867"
     CDS             complement(13894..14667)
                     /locus_tag="KB909_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836923.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            14934..16634
                     /locus_tag="KB909_000868"
     CDS             14934..16634
                     /locus_tag="KB909_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBB6836924.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            16604..16822
                     /locus_tag="KB909_000869"
     CDS             16604..16822
                     /locus_tag="KB909_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBB6836925.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            16842..17732
                     /locus_tag="KB909_000870"
     CDS             16842..17732
                     /locus_tag="KB909_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBB6836926.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            17750..18034
                     /locus_tag="KB909_000871"
     CDS             17750..18034
                     /locus_tag="KB909_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836927.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            18521..19135
                     /gene="gmk"
                     /locus_tag="KB909_000872"
     CDS             18521..19135
                     /gene="gmk"
                     /locus_tag="KB909_000872"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBB6836928.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            19140..19445
                     /locus_tag="KB909_000873"
     CDS             19140..19445
                     /locus_tag="KB909_000873"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6836929.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            19698..22106
                     /gene="priA"
                     /locus_tag="KB909_000874"
     CDS             19698..22106
                     /gene="priA"
                     /locus_tag="KB909_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBB6836930.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            22121..22612
                     /gene="def"
                     /locus_tag="KB909_000875"
     CDS             22121..22612
                     /gene="def"
                     /locus_tag="KB909_000875"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6836931.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            22605..23543
                     /locus_tag="KB909_000876"
     CDS             22605..23543
                     /locus_tag="KB909_000876"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBB6836932.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            23543..24901
                     /gene="rsmB"
                     /locus_tag="KB909_000877"
     CDS             23543..24901
                     /gene="rsmB"
                     /locus_tag="KB909_000877"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBB6836933.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            24914..25654
                     /locus_tag="KB909_000878"
     CDS             24914..25654
                     /locus_tag="KB909_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBB6836934.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            25651..27720
                     /gene="pknB"
                     /locus_tag="KB909_000879"
     CDS             25651..27720
                     /gene="pknB"
                     /locus_tag="KB909_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBB6836935.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            27885..28784
                     /gene="rsgA"
                     /locus_tag="KB909_000880"
     CDS             27885..28784
                     /gene="rsgA"
                     /locus_tag="KB909_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBB6836936.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            28797..29447
                     /locus_tag="KB909_000881"
     CDS             28797..29447
                     /locus_tag="KB909_000881"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBB6836937.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            29448..30086
                     /locus_tag="KB909_000882"
     CDS             29448..30086
                     /locus_tag="KB909_000882"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBB6836938.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            30241..31095
                     /gene="mreC"
                     /locus_tag="KB909_000883"
     CDS             30241..31095
                     /gene="mreC"
                     /locus_tag="KB909_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBB6836939.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            31099..31608
                     /gene="mreD"
                     /locus_tag="KB909_000884"
     CDS             31099..31608
                     /gene="mreD"
                     /locus_tag="KB909_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBB6836940.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            31863..33437
                     /locus_tag="KB909_000885"
     CDS             31863..33437
                     /locus_tag="KB909_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6836941.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT        11031 a         5977 c         7228 g         9207 t
ORIGIN      
        1 ataaaataaa aatatctgtt catctacaaa gaataattta atagaaaagt ttctcaattt
       61 aaaggtttac ctatatgaaa ctagtgtcat ttattttaaa aaccatcgtt taatgaataa
      121 gtagaaagcc gtttctttgt ttatttaaag ttgacactac ggggtacaaa cattagaata
      181 aagttgtgca tgttttttgt acacatatat gcgaagatgc atattgacga gtttagaata
      241 atttatcata gaagctgtat agatgataaa aatgaaaaag atagtatgga ggtggatttt
      301 atggtattca acattctcct cgctatcatc ggtttaattg tcggtcttgg tttagggttt
      361 atggtcgcaa agtcacgtca cgagaaagaa atagctggtg cacaatcatc agctgctgga
      421 atcatcgata gtgcaaaaaa agaagcagaa actctaaaaa aagaagcatt gttagaagct
      481 aaggaagaaa atcagaaata ccgttctgaa gttgaaagtg agctgagaga aagtaagtta
      541 gaattaaaat ctcaagagaa tcgtttgatt caacgcgaac aaacgctgaa tcgtaaagat
      601 gactcgttag aaaaacgcga gaactcactt gaaagtaaag aagaagcact tagttcaaaa
      661 cagcaattaa ttgaagagcg agaaaaagac gttgaaaaaa tgattgaaga tcaacaaaaa
      721 gaactagaaa aaattgctgg tttatcaaaa gaggacgcac gagatgtcat catgaaatcg
      781 actgaagaag agctgaatca tgagttaact ctaatggtaa aagaatctga acagcgtgcc
      841 aaagaagaag cagatcgcaa agcgaaaaac ttattatcat tagcgattca acgctgcgca
      901 gcagatcaag tttcagaaac gactgtttca gtcgttaccc ttccgaatga tgaaatgaaa
      961 ggtcgtatca ttggacgaga aggtcgtaat attcgaacgc ttgagacgct gactggtatc
     1021 gatttaatca tcgatgatac accggaagca gttgttcttt ccggattcga tccaatccga
     1081 agagaaatcg cacggatgac cttggaaaaa ctgatacaag atggacgaat ccatccagcg
     1141 cgtatcgaag aaatggtcga gaaatctcgt aaagaaatgg atgaacgtat tcgcgaatac
     1201 ggggaagagg cagcgtttga agtcggtgct catacacttc atccagatct aatcaagatc
     1261 atcggacgtc tgcgattcag aactagttat ggacaaaacg tcttgaagca ttcggtcgag
     1321 gttgcaaaat tagctggtat cttagcagca gagcttggcg aagatatcca attagcaaaa
     1381 cgtgccgggt tgctccatga tattgggaaa gcacttgacc atgagattga aggatctcac
     1441 gttgagatcg gtgcggaatt agctgccaag tacaaagaaa acccagtagt aatcaacgcg
     1501 atcgcttctc atcatggaga tgtggaagct acttctgtta tctctgtcct tgtagctgca
     1561 gcagatgcgc tctcagcagc aagacctggt gcgcgaagtg aatcattaga aaactacatc
     1621 cgtcgtttaa gaagtctgga aaatatttcg aacagcttcg ccggtgtaga atcaagttac
     1681 gcagttcaag ctggacgcga agttcgggta atggtcaagc cagaagaaat ctcggattta
     1741 gacgctgttc gtttagtacg tgatattcgt aaacgaatcg aagaagaact ggattatcct
     1801 ggacacatca aagtaatcgt tattcgggaa actcgtgcaa ctgattatgc taaataataa
     1861 aaaatacaaa agaagagccg cggcaaaagc cacagctctt ctttttttgt aaggcacgaa
     1921 aaaacattgc tatcattatt ttttattcaa catctcaaga tctttctcga tcgtcgtatt
     1981 gattcctttg atgattgctg ggatgaatcc tgcttcttct aaggcaacta cacctgcaac
     2041 agttgtaccg ccaggagaag aaacttggtc tacaagttcc catggatttt tatcacttga
     2101 aaggaatttt tgacaagaac ccataattgc ttttgcagca atctcagtgg ctgtctgttt
     2161 ggacaaacca ttcagtacac cagtccgtcc catcgcatcg atcagcatgt aaacgaatgc
     2221 gggtgagctg ccagcaaggc caatgaatgt actgaaatct gattctgcta aaggatagac
     2281 gctgccgatt gcttcaaaaa tcatcgtagc ttgctgaagc tgttcctccg tggcagcttc
     2341 atttttgcaa atcgcagaaa cgcctgctcc tacgctgaca ttgacattcg gcatcacacg
     2401 tacgatggag gcctgaggat cttcaagcgc tgtttctaaa tctattaatg attttcctga
     2461 agcaatagaa atgaataaga ctttctggct atattctctt agttcttcca atactttttc
     2521 aatgattttt ggtttcacgg ctaaaagaac gatatctgat tgtgatgcaa cttcctgatt
     2581 acttttgcat gcatggacgc cagtttcagc agcaaatttt tgtgcatttt caaaatgtcc
     2641 actggaaacg aacacctctt ctttcgagac tgttcctttt tttaataaac catcaataat
     2701 agcttgtgcc atattccctg tgccgataaa tcctactttc atgttatcct ctcctttagc
     2761 attaggatat ctttcttttt ctatcatcgc aagcaaagaa caggtctaaa gtggaaaaat
     2821 taaaataaat aagataacat tggggtatga cacaaaagta tacaagttag gaatgggaaa
     2881 atgtgaaaaa taaacgatac ttgatgctgc aatggataaa ggaacatagt ctgattttaa
     2941 aactgatttt tttcggctcc gtgttagtct ttgtggcaaa tcaagtcgca aatattgcta
     3001 atggcatgag ttggcaagat atttggcaaa ggatgggaca acaaagccgc atgacgatcc
     3061 tgctcatgat tctggctgga ctgctgggtg tcactccgat gttgttgtat gattgggtga
     3121 cgatcagagt cttagaaaaa caaggaaaac caaaaatgga aagaaaagag tttcttcttg
     3181 ctgcgtgggt aacaaacacg atcaacaatc tcgccggttt tggtggtgtg gtaggagcaa
     3241 gtctgcgggc tagtttttat ggaaagcaga caaatagaaa aatggtttta gccactgtat
     3301 caaaagtcgc actatttatg ctgactggtt tgtctgtatg gtcgtttctt acatttattg
     3361 atgtcttttt tattcagtca gaaagtattt ttcgaagcta ttggatctgg cttttcggcg
     3421 gtagtttttt agcaccagtc attttctttt ttgcttatct aaagagaaag acattgttct
     3481 tcgagtttta tccaaaaggc ttgcttggtc tgctactggc atcctttgga caatggacgg
     3541 gagcccttgc ggtatttttg atcatcggca agttgatgag aatagatatt tcgatgcttt
     3601 cgatctatcc tatgttcatg attgctacat tgataggaat gctgacgatg gtcccaggtg
     3661 gaatggggac ttttgacgtt ttgatgatct taggaatgag tcaattgtct gttcggcaag
     3721 atgtagcagt agtttggcta ttatattatc ggttgtttta ttatgttcta ccttttatga
     3781 cgggacttct attgttcatc acacatacag gagtcaaaat caatcgattt ttagataaca
     3841 ttccgcgact gtttttccaa aaggttgcgc atatcgtgct cgtaagtgct gtctattttg
     3901 cggggatcat gatggtactt ctatcaacaa tcactaatct gtctgcaatc agtcggctat
     3961 ttcaagtatt attgccgttc tcattcaatt ttttagatca gacagtgaat ctattggttg
     4021 gctttttatt actcggcctt gctagagcac tttcagtaaa agtcaaaaag gcatttctgc
     4081 ctacgattgc tttactatct tttggtattt taaatacaat cacacgtacg ttatcttggc
     4141 agttgatatt ggtatatgtc ttgattctgt tagctgtgtg gttatccaga aaagaatttt
     4201 atcgaacaaa attcgtttat tcttggggag ctataatctt tgatgctagc ttgttcggct
     4261 ttttgtttat cgtttacgca attgcaggct atcacagcgg acgcttttta gtcggtcgaa
     4321 taacaggaaa tcattttatt ttgtttcctt cagatgatgt gtggttctca gggcttattg
     4381 gtttgggcat ctcattgcta gctttagtgg cgctttatca atatttagct gaagatacta
     4441 cgaagcttgg cagtgagtac gaaaaagacc gttttgaccg tttattggaa acatacggag
     4501 gcacagctac aagccatcag cttcgcttgt caggttacag ttatttttat taccaagaag
     4561 acgaccaaga tcaagtcgtt tttggttatc agatcaaagg aaacaaatgc tttgttttag
     4621 gagatccagt tggcaatcct aaaatgatgc gggcagcaac gaatcagttt atgaaacaag
     4681 cagattgttt aggctatcag cttgcgtttt ataagatatc agaaagctac gtagtgatgc
     4741 ttcatgaatt gggttttcac ttcacgaaag taggtgaagc agggattgtt gatctagcaa
     4801 cagaagactt gtctcggctg agtcagcaac ttgaatatca acgtttgatg aaagaaggat
     4861 accattttac ttggtacgat caactgccgg aagaattaca tcaagctgta aatgaagttt
     4921 cacaaaaatg gcttcaaggt gcacgagaaa aatacttctc tgtgggacga tttgataaat
     4981 catatgtatt atctagcggt gtcggtattg tccgtaaaga tcaaaaagtc gttggcttca
     5041 tcaccgctca gccgatgacg aagaagcagg cgggatatga tttgttgcgg gtcttaccta
     5101 aagaatctga ggaattagct gactatctgt tagccaatct gtttattgta tacgagaaaa
     5161 tgggctactc ggaagccaat ctaggcttag ctccattagc taatgttgga gaaacagatt
     5221 tttctttctt tcaagaaaaa gtcatgcata tcgtatataa ttatggtaat tttttctatt
     5281 ccttccagtc tgcttatgaa aagaaattaa aatatgtcga tcattgggaa ggacgttatt
     5341 ttgcttatag gaaaggaagt aatttcggat ttgctaccat gcagctactc agtctgatag
     5401 gaaaagaaaa aggaaatgtt ccgagtttgg cagaagaagt gctcacagaa ttataagaat
     5461 cactagaact tgtttggatt atgaagagaa aattctgtga aagctgttga aacgatgaca
     5521 aaatcaacca ctaggcagac ataagctata cttttatttt tccctatgat agaatacttg
     5581 cgacttagac ttttcgaatg ggtgagagga tggaattgat tgaaaaagcg ccagccaaga
     5641 taaatttagg actggatgta ttatatagac ggcaagatgg gtatcatgag ttggaaatgg
     5701 tgatgtcgag cgtagacttg gcagatcatc tattttttga agaaataaca gaagacaaaa
     5761 tcattgtaga aacaaataaa gcatttttac cggtagatga acggaacaat gtttatcaag
     5821 ctgctttatt gctaaaaaat aaatacaata tcaaaaccgg tgtcaagatc tttgttaaga
     5881 agaatattcc agtagcagct ggattaggcg gaggaagtac agactgtgca gctgctctaa
     5941 gagggatcaa ccaattatgg aatctgggct gttcgttaga agaactggca gaaatcggtt
     6001 tggaagtcgg tacagatgtt ccttactgtg tctacggaag tacggcattt gtcggtggca
     6061 aaggggaaga aatccaagta ttaccttcta tgccacagtg ctgggttgtg ttggtcaaac
     6121 caagaatgag tgtctctaca cgtacagtgt ttagagaagt agatacgcaa gccatccaac
     6181 atcaagacat ccacggactt gctgaagcca tccgagagca agattatcag cagatgatca
     6241 aaaaaatggg aaacagttta gaagatataa cgggaaagcg gcatccagtc atccatcaaa
     6301 tcaaagagcg tatgatcaag tacggagcag atgctgcatt gatgagtgga agcggaccaa
     6361 ccgtttttgc cttgtgtcaa cattattcaa gagcgcagag agtatataat gggttaaaag
     6421 gtttttgtga ggaagtttat ttagtacgaa ccctgcaata aaatataaga agtaaaatag
     6481 gtgatgaaaa actgaggaat cctaaaatgg tattcttcag ttttttattg tagtgaaatg
     6541 gctagatatg agcagcaact catccatttt acgatttaat caagaatata catgcttaaa
     6601 tcagaaattg atggatttct attgactgtg tttttttatt ttgatacatt agttcacgtt
     6661 aataaatcgt aaaattccga tttgttcatt gaaaggagca tataaatgaa aaaatatctt
     6721 ttgacagcta cggtaatgat aggtgcttta ctgtttgcag catgtggaaa tacgaacaag
     6781 gaagcagaca aaaaagagga tttgacgatc gttacgactt tttatccgat gtatgatttt
     6841 acaaaagaga tcgtagggga tgaaggaaac gtgaaacttt tgatccctgc tggaacggag
     6901 ccgcatgatt tcgaaccaag tgcaaaagaa agagcagaaa tttccgatgc agatgttttc
     6961 gtgtataata gttcagacat ggaatttttt gtggattcgt taaaggattc agtggatagc
     7021 aaacagacct tgatgatcga agcagctaaa ggaatcgacc gtttagaatc gcaagaagca
     7081 gacgaacatg aagaatcaga agaagggcat ggtcattcac atgaatacga tccacatgtt
     7141 tggctcgatc cggtattagc tataaaagaa gtcagaacga ttgctgaaga attaggcgaa
     7201 aaatatccag ataaaaagga aacttttacg aagaatgccg atgcttatat caaaaagctt
     7261 gaagcactgg atcaaaaata ctccgatgag ctaaaagatg caacaaaccg cacatttgtc
     7321 actcagcatg ctgcttttgc ttatttagcg aatcaatacg acttaaaaca agtagcgatt
     7381 tcgggcgttt caccagatca ggaacccaca ccaagtcgct tagctgagct aaaagaattt
     7441 gtgaagaaaa acaacatcaa agtgatttat tttgaagaaa atgcctcttc gaaggtagct
     7501 gagacattgt cgaatgaaac aggagtgaag ctagaagtgt tgaatccttt agaaagcttg
     7561 actaatgaac aaatcaaagc aggcgaaaat tatatttctg tcatggaaaa aaatctgaaa
     7621 gctttaaaag aaagtatcaa ttaagtttta gaatggaggt tgtaaggtgc gttatatcga
     7681 aatatctgat ttgacctttt actatgatga tgaacctgta ctagaagatg tctcttatca
     7741 tgtagatgcg ggtgaatttg tcattttaac tggagaaaat ggagcagcca agtcaacctt
     7801 ggtgaaagca tcgttaggat tactgaaacc ttcaaaagga atgataaaga ttgctgagaa
     7861 aaatcaagaa ggaaaaaaat taagtatcgg ttatattcct caacaagttg catctttcaa
     7921 tgcaggtttt cctagtacgg tgatcgaatt agtccgttca ggaagatatc caagaggccg
     7981 ctggttcaag cgtctctctg aaaaagatca tcaacatgta cagcgtgctt tagaagctgt
     8041 agggatgtgg gatatgcgaa atcggcgaat aggtgaattg tctggcggac aaaagcagcg
     8101 aatcagttta gcgcgtattt ttgctactga ccctgactta tttgttcttg atgaaccaac
     8161 aacaggtatg gatgaagaat ccagaaatga attttatcgt cttctccgac atagtgcgca
     8221 tgtccatggg aaatcagttc taatgatcac ccatgatcat gaagatatca aacagtatgc
     8281 ggacagacag atccgactgg tgagaaagga ggattctcaa tggcgttgct ttcatatgaa
     8341 ttcatgagaa gagcgtttct tgccgctatc ttcattgccg gaatcgcccc gatgctaggt
     8401 gtgtttttag tgatcagaag acaatcgctg atggctgata cgctttctca tgtctcttta
     8461 gcaggggtag cgttaggatt ctttttgaac cttaatccta cacttacgac catgctagtc
     8521 gttgtattag cagctgtgat attggagtat ctgcgaacga tctaccgaac ctattcagaa
     8581 atctccattg ccattttaat ggctggtggt ttggcgctag cgttagtatt gatgaatttg
     8641 agcggaggga attcagcaac aagtatccaa tcctatctgt ttggttcgat cgtgaccatt
     8701 acatgggagc aagtcatctt tttaggaatc ttattcgttg ccatcggtat attgttcttt
     8761 ttattcaaac ggccgatgta tgttctgact tttgatgaag ataccgccca cgtggatggg
     8821 ctacccgttc atttgatgtc gatgatgttc aatgtgatta ctggtgtggc tattgctgtg
     8881 atgatcccga ttgccggtgc acttttgata tccgcaatca tggttcttcc cgcagcaatc
     8941 ggtatgcgat taggcaaaag cttcaatgtc gtgattgcta tcagtgtttg tgtaggattt
     9001 ctagggatgc tgtcaggact aactagctcg ttttatctag atacacctcc aggagcaaca
     9061 atcacattag tctttattgc tttgttcctg attgtaaata tcatcaaacg aatattggtt
     9121 gccttcagaa gaaaaaataa ctaaattata aagaaaagaa gccttataaa aacgaaaaat
     9181 tttttatagg cttcttttta ttttaataaa taccgaacta ttttcttatt ttttcataaa
     9241 atgctcgaat ttttgaagaa aaacttatat aatgtaaaac gataaaattt cttaaaagga
     9301 gttggaatag gtgaaagtac gtcgcagtga acgtctagtt gacatgacac agtatttatt
     9361 gaatcacccg catgaattga tttccttaac aagctttgcc gaacgttatg aatctgctaa
     9421 atcttctatc agtgaagatt tgggaatcat caagaaaaca tttaaagaac gagggtatgg
     9481 aaccttggaa acaatcccgg gtgctgcagg tggtgtattg ttcatccctg aaatttcata
     9541 tgaagaggcg aaaaaatata ttgaatctct agcagaacgt ctatcagaac aagaccgtct
     9601 gcttccagga ggatatgttt atctctctga tttgttagga gaacctgaac tgctgcgtca
     9661 agttggaaga atcattgctt ctaaatacct tggtgaaaaa atcgatgctg taatgactgt
     9721 agccacaaaa ggcgtaccta ttgcccaagc tgtgtcctat tatctgaatg cgccattcgt
     9781 tattgtacgc cgggactcaa aaataacaga aggatcaaca gtaagtgtca actatgtgtc
     9841 tggatcttct gaaagaattg aaaagatgga actgtctaag agaagtttga aacgtggttc
     9901 acgtgtcctt gtagtggatg atttcatgaa aggcggcgga acagtcaacg gaatgaagag
     9961 cttgattgaa gaattcgaat cagaacttgt tggcatcact gtatttgccg aatcaaaatt
    10021 caacggtcat cgcgccatcg atgattatac gtcactgctt tatgtcaaag atgtagatac
    10081 tcaaacgaaa aatattacgg ttgtgccagg aaattatttt tcagaataag aggttgtgaa
    10141 aaagccgctt agtttcgagt agtaagaaaa attttgtgaa aatggctttc cacatttttt
    10201 cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttatct agaggttgtg
    10261 aaatcagcgt cctgtcctga gtattagctc aataaacgga aaaattgctc ctcatatttt
    10321 gccgtttatt gagctaatac cgaaggtcag ctgattgaaa aacgtttaat gaagaggttg
    10381 taagcctacc gtttaactct aagtcacaag aaacgatttc aaaaaacagc ttttcatgtt
    10441 ttatgagtag tgtgacttgt gaccgaggag ttggcaggag agcaccggtt accaaataga
    10501 taggcccgtt atggtctatc tattttttta tccagaaaac gctgggataa aagaaaatca
    10561 cttgttttgt tgaaaaaatg ggtatactgg gataaactga aatcagcaaa ctatatttag
    10621 gagtgacgca gttggacgca cgttatgcaa ttattttggc ggcagggaaa ggtacccgca
    10681 tgaagtcaaa attatataaa gttttacatc ccgtttctgg taaacctatg gtagaacata
    10741 tcattaatcg ggtcagtgaa acgaaaccag atgaagtgat tacgatcgtt ggacacggag
    10801 cagaacaagt taaagcacaa ctaggagaac gcagtaaata tgcgttacaa gcagaacaat
    10861 tgggaacagg acatgctgtt ttgcaagctg cttctttctt ggaaggaaaa aaaggaacaa
    10921 cgttagttat cagtggcgat acaccattat tgactactga aacgctgaac aatctttttg
    10981 aatatcacca aggaaaaaat gcaagtgcaa cgatcttgac ggcacaagca gaaaacccaa
    11041 caggatatgg acgaatcatc cgtgaccata ttgggatcgt agaaaaaatc gtggaacaaa
    11101 aagatgcaac accagaagaa gctcttgtac aagaaatcaa tacaggaact tactgttttg
    11161 acaacgaagc tttgttcgat gcgttaagca aagttggaac aaacaatgct caaggtgaat
    11221 actatctaac agatatcatc gaaatcttaa aagaagaagg ccatacagtt gctgcttatc
    11281 aaacggatga ttttgaagaa tcaatgggag tcaatgatcg gatcgcgtta gctaaagcaa
    11341 atgagatcat gagaaagcga attaaccaga tgcatatggt caatggcgta agctttgtcg
    11401 attcagcaac gacatacatc gatgcaggcg tagaaatcgg tccagacaca ttgatcgaag
    11461 caggtgtaca aatccaagga aatacagtca ttggttctga ttgtgtcatc gggtcacatt
    11521 caaaaatcgt agacagtagg attgaggatc acgtcgtcat tgaaaactca gtcattgaaa
    11581 gcagccatgt caagaaacat gcagatgtgg gaccttatgc acatttacga ccaaaagctg
    11641 aaattggcga aaacgtccat atcggaaact ttgtggaagt gaaaaatgct caaatcggca
    11701 aaggaactaa agtcggtcac ttgacttatg ttggtgatgc tacgctggga gaagaaatca
    11761 atgtcggatg tggtgttgtc ttcgtcaact atgatggaaa gaacaaacat catacgactg
    11821 tcggcgacca cagctttatt ggttctagca cgaatatcat cggacctgtc gaggtagcta
    11881 aaaacagttc gattgctgcc gggtcaacaa ttacagacaa tattccagaa tatgcgctgg
    11941 caattgcgag agcaagacaa gtcaataaag aaggatatgc aaaaaaactc ccttatctaa
    12001 actaagactt ttgcaaaatc acttgattta tttaaaaaat atgactacta tttattaggt
    12061 agaattctag agttgtgaaa aagaaagtgg aggtccccat gtcaaaacat tactttgacc
    12121 caagattaaa aatttttgcg ttaaattcca atcgcccatt agcagagaaa attgcagcag
    12181 cagtcggcgt cgagttagga aaatcatctg ttactcaatt tagtgatgga gaaattcaag
    12241 taaacattga agaaagtatt cgtggatcgc atgtctatgt tattcaatca acgagcagcc
    12301 cagtcaatga taacttgatg gagttgctga tcatgattga cgcactgaaa cgagcaagtg
    12361 caaaaacaat caacgtagtc atgccttatt atggctatgc gcgtcaagac cgtaaagcac
    12421 gtgcacggga accaatcaca gcgaaattag tagcaaacat gattcaaaaa gctggtgcaa
    12481 caagaatgct gactttggac cttcatgcag tccaaatcca aggtttcttt gatattccag
    12541 tcgatcattt gatgggtgcg ccacttattg ccaattattt cttagaaaaa ggaatcaaag
    12601 gcgatgatgt tgtcgttgtt tcaccagacc atggtggtgt cacacgggca cgtaaattag
    12661 cggaattttt gaaatctccg attgcgatca tagacaaacg ccgtccaaaa gcaaatgttg
    12721 cagaagtaat gaatatcatt ggacaagtca aaggcaaaac ttgtgtactg atcgatgata
    12781 tgatcgatac agcaggtacg atcacattgg ctgccaatgc tttgaaagaa gctggtgcaa
    12841 ctagtgtgta tgcttcatgt acacatccag tattatccgg ccctgcttta caaagaatag
    12901 aagattcagc tatcgagcgt ctagttgtta cagactcgat ctatcttcca gaagatcgta
    12961 aaatcgacaa aatcgatgaa gtaagtgttg gcggactaat gggagatgca atcaaacgta
    13021 tccatgaaaa caaaccagtt agtccattgt ttgaaacaaa aaataaataa taaataaact
    13081 cacaaagggg agtccaattg ggctgagatt gaatctattt ctaaaccctt cgtacctgta
    13141 tcggttatgc gagcgtagga attgtgaata aacagctgtt tgactatttt cgaaagctgc
    13201 ttcctccttt gtgacttttt tattcaaagg aggaagtttt tttatgggaa aaaatagagt
    13261 ttgggtagaa ggaacgattg ttgcagcgtt agcgatggtg ttgtcgttga ttccgatcca
    13321 gatcggcagc agtttttcta tttcattagg gcagattcca ttgactcttt ttgcgttaag
    13381 aagagggaca aaggcaggga tgctggcagg tttcatttgg ggcatcctac attttccgtt
    13441 gggacaagtt tattatttaa gtgtcgttca agtgttgatt gagtacccga ttgcctatac
    13501 ttttgcaggc gcagcagggc tcatggcttc aaatgtccaa aaaggctatg tagacgataa
    13561 tacgaaacaa attagaaaaa gcatcgtgtt tggtgcattg attggcgcac tttccagata
    13621 tttttggcat tttattgcag gagtggtttt ctggggagcg tatgcactat gggggatgaa
    13681 tccttggctc ttttctttcg taatgaatgg tgccagcggg ttgagtacag ctattgtaac
    13741 gatcatcgtt ttattaggga tccaacaaac gactccttcg atttttgtgc cagataaacg
    13801 acaggagctg taaataaaaa agaagcaaga aacttgagac agaatcatgt cctagtttct
    13861 tgtttccttt ttattttttg ataagaaata gatctacttc aatggcagat aagaaagatc
    13921 ggcatcttct accaattgcc agtgtcgatc ggtgacagag tagattaaag tagcgatgat
    13981 ttcctcttct cgataccggg tgccttttaa tttccaaata taatcttcaa tcacatagat
    14041 tgggatacga tatttaccat cgatcaaacc aacttgatca aaagaaaaaa tgatcccttc
    14101 ctgcatcaaa ttacgcattt ctttcaataa ttccacactg attttttcaa caggtgtttc
    14161 ttttttgaaa aaagattttt ttacattgat cttatctgac aagatcgaac ttaatttact
    14221 agcaaaaatc ctataaaatt catctaaata gcgataataa atccgattca gctgatcatt
    14281 aagatcgaag tatacaaaat tattctgtag tttataaaaa aacggcgaat gaagatgtgt
    14341 tttcatatga ccaaaatata ataattctga aatttctaaa ggtgtcaatt ctttcagcat
    14401 cgttaaatca gtaaagtcga tccacttcaa ttcatcgaat ccacgcctgt tacgagaaga
    14461 ggaaaagaaa cgctgaatat tttctgtacc acggattact ttcagccctg tatgggattc
    14521 atattctcca gcagaagcag atggatcaag caagagcaag ttttgaggaa aatgcacgat
    14581 actgtttgca aagtcagtag cagtcagccc ttttgttaaa acagcattac ttgtggtatc
    14641 aatatgtaca taaactgact cagtcatcat gttcctcctc ttatttcctc ttaatctctt
    14701 ttattttaca acatttgcat taaaaaagct tgtttctttt attttaaaat tccattacaa
    14761 aatcacgttt tcattgaaaa cactctcatt ttcaattaat ttttgtgatt tttgtatttt
    14821 tttatttaaa ggaggtttta tgaattgttt tcttatggaa tctacaaagt cgaatacgag
    14881 actcatgacc tttttatgac gtactggtat acttgaagaa aaaggagagc gcgatggaga
    14941 taaaaaaagt ttacttttca cagaaaatgt cgctgtattc gcctatccag caagcaaaac
    15001 aaccccttcc attttttcaa agtcatcaag aaagtagaga cgctttttgg cgttctgcaa
    15061 aaaagcaatg tgcttttaaa gcagtatcga aaaaatatac cgtctatttt actattgcta
    15121 aaagtagagg agatgttatt tttaataatc tgttgattga aggtgaaact tttgaatgga
    15181 aaaaattttt tcggtatatg gaagcttgcg ctcgtttttt tattaaagaa aactgttgtt
    15241 ttttatttca atctcctcta tcagaagaat ggttgcgtat ttttcataaa aacggctatc
    15301 aaggaaccac acaattaaat aaaaagctgg tctatcatac agcacttgtt ttaggtggag
    15361 gaggagcgca cggtgcttat cagattggtg tgtggcaggc gctgaaggaa catgatatca
    15421 actttgagat tatcacaggt acctcggtag gtgcgttgaa cggcgcattg attttacaag
    15481 gagatatgaa aaaagctgtg aatttatgga aaaagctgtc gacaagacaa gtgcttgcgt
    15541 taccagaaat ggctgcagtt gaagaccttc gtgaacgctt ctatcgagaa agacgccaaa
    15601 tgacgaaaac agcactaatt gaaggcgggg tttcttctgc tccattggaa aagatggtca
    15661 aagacaattt ggatttgtcc ttactcaaac ataatcccaa aatacgttta tatacggtgt
    15721 ctactaaact gccagaacta gcggaagtag tgactgatat ccaacagaca aaaacagaag
    15781 aaataccaga ttggatactc gcctctgctt cattttatcc cgctatggct tatcgaaaga
    15841 tcggaaaaaa taaatatgca gacggtgggt atcgcaacaa aatacctatt gatattgcga
    15901 ttaacaaagg agcaacagag gcatttgtcg tagatgtgca agggccaggc ccagcgaaaa
    15961 aaattcgtat gccagacatt tttatccatt ggaaatgtca aacattgtgg acactaggca
    16021 gctttctgct ttttgatagc caaaggaacc aattaaattt acaattaggc tatctggaaa
    16081 tgaaaaaacg attaggctat tactatggga actggtatac atttcattct gttaaacctg
    16141 caagaacata ctggcgagga tttttgtctt acttaacaaa agaaattcag ttagaattat
    16201 cttttttcaa aagcataaaa ttttggcaaa aactgcgtaa tttatataag aacagggtcg
    16261 taccagagac atgcggattg gcgatgctag aacttttagc aaaaaaacat tttttactgc
    16321 ccaatgaaat ctatcaagta gacatgatga ttcaaatgat ctgccaacaa gatataaaaa
    16381 gtatgccgga tgatttattg gcacaaattg gtcaattaag tactgaagaa tggcgaaggt
    16441 atcgaaaata ccagcaaaaa atacaaaatg agcgcacgaa aactgtttat tttgattatc
    16501 tgctacaagg aaaacgcaag gatcgtttgc agcatgaatt gcttaagcaa ccagttgaca
    16561 cattactgat cctatattta tattatctca aggaggaaca accatggcac aagaattttc
    16621 atatgaaatc gtagaagaaa tcgctatatt gtcagaaaac aacaaggggt ggcgtaaaga
    16681 actgaaccta gtcagctgga atggtcgccc gccaaaattc gatcttcgag attgggcgcc
    16741 agaccatgaa aaaatgggga aaggcctgac attgacgaac gaagagtttg aacaactgca
    16801 aaaagcaata gaaaatatgt aatgaggaag gaccctgtcg aatgaaaagt atgactggtt
    16861 ttggcaaagc catccgcgaa acaaaagcgt atcagttaga tattgaaata aaaagtgtca
    16921 accagcgttt tctagatgtt caaatacgaa gtcctaaaat cctgaacttt gttgaaaacg
    16981 attttcgtca gcttattaaa cagcagttaa gccgcggtcg aatcgaagta tttgtgaatc
    17041 tagcttatat tggcaaaaac gaaaaacaga tcgtcatcaa ctgggaattg attgattcac
    17101 ttatcactca attgacagac ggaattcaac aacgatacgg tagtcaaaat caagtgtcaa
    17161 ttagtcggat ggcggaacgc ttcgtgctgg acgaaaactt cgtaacggta gaagaaaaac
    17221 cggaagagag catggaagaa ttggcacagt tagctctaga tacattgaaa agcgcacttg
    17281 attctattga ggcgagtcga gaaaaagaag gtcaagcttt agctttagtg ttgaaaaaga
    17341 atactgaaga attcaaagaa gtactaaaaa aactcgatag ttttgtagaa atctatgaaa
    17401 aggaatttca aataaggtat caaaaaaagc tggaggaatt tcttggagcg aaagtcgatg
    17461 agcaacggtt gttgacggag ctagccatct tgttggaacg cggagatatt cacgaggaac
    17521 tggatcgtct ggcgatccat gtacaaaaac tagatgaact tatcgaagca caatgtcctg
    17581 taggtcggga attagatttc ctgatccaag aaatgaatcg ggaaatcaac acgatcggtt
    17641 ccaaatcaaa tgcaatcgaa attaaaaatc aagtcgtcca gtctaagacg atcttagaaa
    17701 aaatcagaga acaagtacaa aatattgaat gacgaaagag gtagagataa tgaaatatta
    17761 tgacgtaacg ttccacgaat taagtggaaa aactgtggtt aaacgggata tcccttctga
    17821 aaaaaacggc tttgacgtat ggaaagatgc ctgtgcagac tataatgaga acgaactgtt
    17881 tattttgatc aacgacggtg cttacgtgac gatgaatcgg aaatttattg ttcgaattga
    17941 cacagaagag gtagaagatc cgacagaaaa agcacgttct cgaaaagatg agatcatggg
    18001 tgtagtgaat actttgtcca atatgggctt ttagcaagga tgctgaacaa agaaatacaa
    18061 taaataaaca gaattggatt tcttcgctta gcttctttgc tctaggaata catttaaagg
    18121 ttgtgacaaa attcgtgtca caatcttttt ttattttgaa taagtgatgt tcaaaaacca
    18181 ttttctcggt attaagccaa atttatgcaa aaatgtgaga aactattttc acaaaatttt
    18241 tcttcatact cgaaactaat cggcttcttc acgacctctt atacacggcg ttcaaaagct
    18301 tgcatctgcg ataataaccc caaccaaacg aaaaacatga gaagctgttt atgtttggct
    18361 gttcttatta cttgatgcag gacagctttt ttacgacctc ttggtacagg gtagcttttt
    18421 taccaatttc tagctataat taaagataac cttgaaagtt gcagaaaaaa agtgcaaaat
    18481 aaacgataag tacaaaaaga ctagttgaaa ggacgtcgtc atgtcagagc gtggattatt
    18541 aatcgtgttg tctggtccat ccggtgtagg aaaaggcaca gtacgaaaag caatttttga
    18601 gagtgaggat aatgattttc agtattcgat ctcaatgact acccgtaaaa tgcgtgaagg
    18661 ggaggtcgaa ggcgttgatt atttcttccg aagcaaagaa gagtttgaat caatgatcga
    18721 agctggagag atgctggaat acgcagaata tgtcgggaat tattatggaa ctcctttgtc
    18781 atatgtcaac aagacattgg atgaaggaaa agatgttttc ttggagattg aagtccaagg
    18841 agcaaaacaa gtcaaagaaa aagtgcccga tggtgtattc atctttttga ctccgccaga
    18901 tttagcggaa ttaaaatcac ggatcgtagg ccgaggaaca gatgcagatg aagtaatcga
    18961 aaaacgaatg aaagttgcaa aagaagaaat cgaaatgatg gctctttacg actatgctgt
    19021 tgtaaatgat gaagtgccgc tagcagttga acgaatcaaa aacattattg ccagtgaaca
    19081 ttttcgagta gatcgcgtaa tcggtaaata tattaaaatg ttaaaggaga tgtagtctta
    19141 tgatgttaaa accttcaatt gactcactat tagatcgtgt aaattcaaaa tattctctag
    19201 tgattttagc aagtaaacgc gcgcatgaat tggatgcaag tgcacagcct actctagatt
    19261 cttttgattc agtaaaaagc gtcggtcaag ctttagaaga aatcgatgca ggaaatgtag
    19321 tcaatgatcc acatcctgaa ttaaaacgtg aacgtttgaa gatggaagaa gaggaacgtc
    19381 aagcacaaaa agagcgtgaa caacacgaat tggaatcacg tatccgtgaa gagcaaaaaa
    19441 tgtaataaag aaaaatagag cgaacatcta aaaagaaaag caaacccagc tgtttccttt
    19501 tcaaacattc gccacttatt gtctggtaga aaaggctgtg tctgaacttt ttgacacagt
    19561 tctttttttt cttatctgct gttaattttt tgttaggatt tggcagaaga taagacaaat
    19621 ccatcgatct ctagtaaaat aggcaaggaa ctttttgtcg cttgataaga aaagacaaaa
    19681 aaaggaggaa acgaaccatg acattaacag ctgaagtcat tgtggacgta cctactatgc
    19741 agaccgatca gccattcact tatttggttc cctctgaaat ggaaacagct ttgcaagtcg
    19801 ggatgcgagt agaagtccct tttggtaatg gcaatcgtca tgtccaagga tttgttatgg
    19861 ctatccaaaa atcagaagaa tcagctaatc catctttgaa ggcagttatt cgtttgctag
    19921 accttgctcc ggtggtcaat gaagaattac tttcattagc tgattatatg aaaaaaatta
    19981 cttacgcatt caaaatcact tgtctacaaa cgatgcttcc gagtgtgatg aaagcagaat
    20041 atgataaatt gatctatcct ttggcagaca caccagaagt tcaggtattg tttgatcagc
    20101 gagaagtgat ttcctggaag gaagcagaag aagaaggcag cctttctcaa ttgattcgct
    20161 ggcgccaaga gcaattagta gatatcaaat atgaagtcca tacacgaaat aaagtaaaaa
    20221 cgattcgttt ggtccgttct ttgttaactg aaaagcaaat cgaagaagaa tgggcaaaat
    20281 tacggcaaaa tgccaagaaa caaaaagaac ttcttttgtg tttatctgaa ctgagccaag
    20341 aagaaccaat tgcttatttc aaaaataaag gaatcagtac tgctgtcttg aatcaaggaa
    20401 aagaaaaggg ctggctggag tttatagaat cagaacgtta tcgcgaccct tataaagacc
    20461 gagtatttga ccaaacgacg gcattggaac tgaatgcaga acaaaaaaat gctgtcgaac
    20521 aaatcatcac agcaggtcag cagcaaaaag atcaggtctt tttgctggag ggaatcactg
    20581 gcagcgggaa aacagaagta tatcttcagg caatcgctga tgttttgtca gaaaataaaa
    20641 cggctattat gttagtgcct gaaatcgcat tgactccgca aatggtcgag cgattcaaag
    20701 gacgcttcgg agaatcagtt gcggtcttac atagcggact ttcccaaggt gaaaaatatg
    20761 atgaatggcg caagattgag cgggaagaag cgcaagtagt agtaggcgca cgatctgcta
    20821 tttttgcccc gctgaaaaat atcgggctga tcattatcga tgaagaacat gaatcaagtt
    20881 acaaacaaga tgagacaccg cgttatcatg cgagagatct agcaatttgg cgcagtaaat
    20941 atcatcattg cccaatagtt ctaggaagcg cgacgccctc tttagaatca agagcacgag
    21001 ctcaaaaagg cgtttatcag ttattgcagt taaaccaccg agccaaagca gctgcacagc
    21061 ttccagctat tgagatcgta gatatgcgtg aagagtttca gaatcatcgg acctctactt
    21121 tttctgctaa tttgcaggaa aaaatacaaa atcgattaga caaaaaagaa caaactgtcc
    21181 tactgctcaa tcgtcgagga tattcgtctt ttgtgatgtg tagggactgt ggatttgttc
    21241 ttccatgtcc taattgcgat atctctctta cactgcatat ggatacacgt tcaatgcgct
    21301 gccattattg cggacatgaa gaacctattc ccaatcgctg tcctaattgt ggcggcaata
    21361 aaatccgcta ctatggaaca ggtactcaaa aagtagaaga ggaactccga gaactttatc
    21421 cgcaagctag gattttgcgt atggatgtag ataccactcg aagaaaaggg gcacacgaac
    21481 agattttaca aaaattcggt gcaaaagaag cagatatatt attagggaca caaatgattg
    21541 ctaaaggttt ggactttcca gaagtgacat tagttggggt gttgaatgct gatacctccc
    21601 tgaatttacc ggattttcgt tctagtgagc atacattcca attgcttacc caagtttcag
    21661 gacgagcagg gcgagcggaa aaagcaggcg aagtcgtgat ccaaacattc aatcctcaac
    21721 attacgccat agaattggct aaaaaacaaa attatgagca gttttatcag caggaaatgc
    21781 atgtacggca tcgtggaggc tatcctcctt attactttac tgtgaaaata accgccagcc
    21841 atcctgaaga acaagtagcg gcaaagaaaa tctttcagat tgccaatcag ctaaaagaag
    21901 tgttaagccc tcaaagcttg ctattagggc caacgcccag catgattttg agagtgaaaa
    21961 accgatatta ttatcaacta atcatcaaat ataaacatga accgaatctt cctcatgttt
    22021 tggatgaaat tttgaatgga agccagaaag aacagcgaca aggtcttttt gtggcaattg
    22081 acaacgaacc attaaacttt atttaagaaa gggccaaatt atgcgctatc ctatattgat
    22141 ccaccctaat gataaattaa aaagaactgc tcagccaatc gatgtaatca cggacgagac
    22201 aatcgcttta ttagacaatt tatatgagac aatgattgcg aatgacggaa tagggatcgc
    22261 tgctcctcaa gtaggacaaa acaagagaat tgctgtgatc gaagtagatg aaggcgagaa
    22321 atttgaactg attaacccag aaatcatcga agcaaaaggt gaaagccttg acgtagaagg
    22381 ttgtctcagt attccgcatg tctatggaac ggtcaagcga gcagatgaag tgaccgtgcg
    22441 ttattatgat cgagacggag aagagataga agtgacggct tttggctatt tagcccgtgc
    22501 cttccagcat gaaatcgatc acttagacgg tatcttgttc attgagaaaa tgatacagca
    22561 gatcccggaa gaagaacttg aagaatatat ggaggaacat cttgatgact aagctagtat
    22621 ttatgggcac acctgctttt tctgtgccga ttcttgaagg gctgatagaa tcaggttacg
    22681 agatccaggc agtggtaaca cagcccgacc gtccagttgg gcggaaacga gtaattacgc
    22741 cgacaccggt aaaaaaagcg gctctgaagc acggtatccg tgtgctgcag ccagagaaaa
    22801 tctccggttc gccagaaatg gaagaaatca ttgaattggt gcctgatgtg atcgtcactg
    22861 cggcatttgg ccaattcttg cctgaaaagt tattgcaagt accaaaatta ggggcaatca
    22921 atgtccatgc ttctttactt cctaaatatc ggggaggtgc gcctgttcat tatgccatca
    22981 tgaatgggga gaaagaaact ggtgtaacga tcatggaaat gatcaaaaaa atggatgcag
    23041 gcggaatcta tgcgcaagaa agcataccaa tcactaaaca agatgatgta gggacgatgt
    23101 ttgaaaagct tagcctttta ggaagaaagc tattgctaga aacattgccc aatattttgg
    23161 atggacaaaa accagtacct caagacgagt cagaagcaac tttttcgcca aacatcacac
    23221 gggaacaaga agcaatcgat tggcataaaa ctgcagaaga aattgacaac caagtacgcg
    23281 gaatgcgtcc ttggccaatt gcattcacga cctatgaggg catacgctgg aaattattat
    23341 cggttgaagt attggcagaa actacagaca aagcacctgg tacgatcatc cggaaagaca
    23401 aaaaaaatct atggattgct tgcggtaaac agaccgtctt agccatcaat gaattacagc
    23461 cagctggtaa aggaaaacag gccgtacatg atttccttaa cggaagcggt cagcaagttc
    23521 agattggtca gcaggtgaaa taatgaaaaa aatccctaaa aaaatgaaaa aatcagtacg
    23581 atatatggca ttactgacat tagagcgagt gaacaagggt ggcgcctact cgaatctttt
    23641 gttgaatgag atgatcaaac aaagcgagct aaatcaaaaa gatgtgggtt tatttacaga
    23701 attgatctat ggtacgatta gccatcagcg actattggaa ttttacgttg caccattgat
    23761 cgctaaagca aaaaaagtgg atgactgggt caagatgctt ctttatcttt ctgtatacca
    23821 attagaattt ttagataaag tccctgcaca tgctatttta aacgaggcgg tcgaaatcgc
    23881 aaaagtaaaa ggaaatcctg ggacagggaa atttgtaaat ggtgtcttga ggaattatca
    23941 gcgtcaagga gcaccagatc tgcaaggcat tgctgatcct atcgaaagac tttctgtcaa
    24001 aatcagcctg cctctatgga tgacgaaacg actggtggat caaatcggat acgaagaaac
    24061 tgaaaagctc ggtttatcgc tatatcagcc tagccatgct agtgcccgag tagatacacg
    24121 ccgactttcc agagatcagg ccatcactgt tttgcaagaa gaagagatca cagctgaaaa
    24181 aagccaagtc agtccatacg gtatagtagc gaaaaaaggg catttagctt ctagctcatt
    24241 gttccacgat ggcgtcatga cgatccaaga tgaaagttcg atgcttgtag cgccgtctat
    24301 gcaaatcgag cctgaacatc atgtcttaga tgcctgtgca gcacccggag gtaagacgac
    24361 gcatattgct tcttttttag atccgtcatg cggtggagaa gtggtcgctt tagatgtaca
    24421 cgaacacaaa gtcaaactca ttgaagataa tgcagcacgt ctaggtgtct cttctgctgt
    24481 ctacgctcaa aagatggatg ctagagaagt cagtaaacag ttcgaagcag agcagtttga
    24541 tcggatttta gtagacgcgc cttgttcagg tcttgggctg cttcggcgaa aaccagatat
    24601 tcgttataaa aaacagccgg atgaattagc gaatttacca aaaatccaat tggaaatttt
    24661 agaaagctgc gcaccaactt taaagtcttc cggtattctg acttatagca cttgtacgat
    24721 cttaaaagaa gaaaaccaag acgttgtttc tgctttcttg gaaagacacc ctgattttga
    24781 gaggattgat gttttgacca atcctatgct acaatcatca atcgaagaga aaatgttgac
    24841 tttgtatccg catcagtttt acacagatgg atttttcatt tgttgtttgc gcaaaaagta
    24901 atgaggtgaa aaaatgcaga ttgaatatca atcagatgta ggaagacgac gtaacacaaa
    24961 tcaagactat gccagtgtat ttaccagccg ttcaggtctc aagcttgctg tattagcaga
    25021 cgggatgggt ggtcatcgtg ccggagacat tgccagtcag atggcggtaa cgaatctagg
    25081 cgaagcttgg gaaaaacaag aagctgttga cgatgaaaaa atcgcccaat ggttcattca
    25141 atcgattcaa gaagaaaata tgctgattta tcagcgtgga caagaacagc cggaatataa
    25201 cggtatggga acaacaatcg tagcggccgc tctgtcagat gactggttca cgattgccaa
    25261 tgttggggat agcagagctt atttgattcg tgaagataaa atcatgcaat tgacggagga
    25321 tcattcttta gtcaatgaac tagtcaaatc aggagaaatc agcgaagaaa tggcagtgaa
    25381 ccatccaagg aaaaatattt taacacgttc tgtcggcatg cctggaacag tcgaagtaga
    25441 tgtttctact catctttggc aactaaaaga tcgactgctg ttatgttcag atggcttgac
    25501 gaacatgctg tctgaagaag aaataggaac gatcatcaat caagaaggcc cattgtctca
    25561 taaagtaact gagctgattg atcgtgccaa tgaagcaggc ggagcggata atatcaccgt
    25621 tcttcttatc gaatataagg aggacagtgt atgatcgagt tgggcaaaaa attaaatggc
    25681 cgttatcaaa tcactggaaa tatcggtagc ggtggtatgg caaatgtatt tttggcgcac
    25741 gatttaatct tggatcgtga tgtagcagtt aaagtcttac gatttgactt tcaaaatgac
    25801 cagactgcga ttcgacgatt tcagagagaa gctttagcag caacagaact cgttcatcca
    25861 aacattgtta gtgtttacga tgttggtgaa gaagacaaca tgcagtatct ggtgatggaa
    25921 tacgtcaaag gaatggactt gaaacgatat atccaaacac attatcctgt tccttatgaa
    25981 acagcagtaa atattatgca gcagatcctt tctgctattt ctttagctca taaccatcaa
    26041 atcatccacc gagatttgaa accccaaaac gtactgatcg ataatgaagg tgttgtaaaa
    26101 atcacggatt tcgggattgc tatcgcttta tctgaaacat cgatcacgca gacgaatacg
    26161 atgctaggat ctgttcatta tctgtcccct gagcaggcca gaggaagtat ggcaacgaag
    26221 cagtcagata tttatgcttt agggatcatc ctttatgaga tgttgacggg tagcgtaccg
    26281 tttgatggtg aatctgctgt aacaattgct ttaaaacatt ttcaagatga tcttccatct
    26341 ataaaagcac ttgatccaaa tgtgccacaa gcactggaaa acgtgatttt acgggcaacg
    26401 gctaaagaac ctgcagaccg ttataagtca gccgaggaaa tgtctgatga tctttctaca
    26461 gtattatcac cagctcgtgc aaacgaagaa aaatggcagc ctcatgtgat ggataatgaa
    26521 acaaaagtta tcacacccct tacggaagat gcaccaatgc ctgattcatt caaatctatg
    26581 cctctgccaa aagacaagcc agaaaacgaa accttaccag aggaggaaga agttctgcct
    26641 gatcctaaaa agaaaggaca gaaaaaatgg tggctgatcc tattagctat tcttgctgtt
    26701 ttaggaatcg gaacagctgt attctttgct tctggcgggc gaggagaagt tgttgttcct
    26761 gatgtttctg atctttctga agcttctgct agagaaacac tcgcaaaagc gaaattagaa
    26821 gtagcaacaa aaacagaaga aattgcagat gacaaaatcg aagaaggtaa tgtagtgaag
    26881 acagacccgg cagcgggaac gacagtcaag caaaaacgcg aagtcactct gtatattagt
    26941 agcggcacga aaaaaatcaa attagatgat tacagtggta aaagttatga agatgccgaa
    27001 gcaagtttga aagaattagg gttttctgct gacttgattc aaaaagaaga ggaattcagt
    27061 tcagaggtag aaagcggaat gatcatttcg caatctccat cagaagatac agaagtcgat
    27121 cctaaaacag acacgattac tttcacagtc agcaaaggac cagaaacagt gactttgagt
    27181 agtcatgtag gagaaaacta cgaaactgtt cgtaattggc ttgttacaca aggattcaat
    27241 atcaataata ttagtgctac ttatgactat agcgacactg taccatcagg ttcgatcatc
    27301 agtcaggatc cagcctcggg tgaagttgta gcagaagaaa cttacatcaa ttttgtcgta
    27361 agccaaggaa cagagcctaa attgaatgat atctccggct atacaaaaag cgaagcacaa
    27421 agttatttag ctagtgtcgg tgcagaatat atcgggcatg agacttccga atattcaaac
    27481 acggtggata aagataaagt gattcgtaca gtaccagggg caggaacgac aattaccaaa
    27541 ggaatggttg tgaacgtaat ttactctaaa ggaccagatc cagcgtcttc tagttctgaa
    27601 aaagactctt cagacagttc tagcagctca agtagctcca gtagcacaag caactcttca
    27661 aaagaagaat cttccagctc cacaagttca tcagctagca cctcagaaag ttcaaaataa
    27721 gtgctgaata aaatatatca gaagggaatg cgacattgat ttgttgcatt ctcttttttg
    27781 tgtttctatc tcttttgatc aattttcaag ccatatactt tgagaagttt gcatggaata
    27841 acacctactt tcctcttcgt atggtaaaat aaacaaaaac ggaggtggca cttatcaaag
    27901 gacaaatcag aaaagcaatc agcggttttt actatgtata cgcaaacgga gagacctatc
    27961 aaacaagagg aagaggaaat ttccggaatc ggaaaatcac gccgcttgtc ggagatcagg
    28021 tgatctttga gagtgaaaat caaacagacg gctatcttct ggaaatcttg ccgagaaaaa
    28081 atcaattagt tcgcccacca gtcacaaatg ttgatcttgg aatcattgtc acaagtatcg
    28141 tagagcctgc attttcttat aatctacttg accgctttct agttaccttg gaatacgagt
    28201 cgatcgaacc gattattttt ttgacaaaga ccgacttgtc agacgaccca gaaaaaatcg
    28261 aagagatcaa gcaaacctat actaaaatag gctatccggt gattgtaccc aatcatacgg
    28321 gtgatacgac agaactgatc cgttacttcc cagaacggct atcggtcttt atgggtcagt
    28381 ctggagcagg aaaatcgacg ctactgaatc aaatatcacc ggaactgaat ttagcaacag
    28441 gagagatttc tgatgcactt ggaagaggac ggcatacaac acgtcatgtg gaactgattc
    28501 ctatctatgg cgggttagta gcagatacac caggatttag ctcgattgac tttttgacaa
    28561 ttgaagcagg agaactgccg agacaatttc ctgaatttgt agaagcttct gtccattgca
    28621 aatttagaga gtgcatgcat gctaaagaac ctggctgcga agtaaaacat agagtagaaa
    28681 caggtggtat cgcacagaca cgttacgaca attatttgca attcttacaa gaaatcgaaa
    28741 aaagaaaacc aatgtatgca aaaaaagaag gtaaacgaaa ataggaggaa acaagaatga
    28801 agatagcacc atccattttg agtgcagatt ttgccaattt acaaagagac attgagttag
    28861 tggaaaaagg aggcgcagat tacatccacg tagatgtaat ggatggccga tttgtcccaa
    28921 atatcacatt agggccaaat attgttcagg caatccgtcc tgttactaaa ttaccgttag
    28981 acgtccatct gatgatcgtt gatccagaaa actacattcc agcatttgca aaagctggag
    29041 cagatatcat tactgtccac gtcgaagcaa ctcctcatat tcatcgggca cttcaaatga
    29101 caaaaagctt aggagttaaa gctggagtag ttatcaatcc aggaacacca gtctccatga
    29161 tcaaacatgt tttgcctttg gctgatcaag tactagtcat gactgtcaat cctgggttcg
    29221 gcggacaaag ctttattgaa gaaacagtag aaaaaattac ggaactcgct gatctacgta
    29281 gagagaacaa ttggacttat gcaatcgaag tagatggcgg aatcgttcca gaaacagcaa
    29341 aaatctgtaa agatgcaggg gcggatgtct tcgttgcagg atcatatatc tatggagccg
    29401 aaaatccagt cggacaaatc gaacgattaa aagaggcatt agactaaatg aaaattttat
    29461 tagctgctgg aggtaatccg caaaactggc cgcagtctct gctgtccaaa tacgatgcct
    29521 atgtcgggat agaccgtggt gcgctgtacc tgcttcaagc aggctaccca gtagatctgg
    29581 cagtgggtga ttttgattca ttgtcgaacg aagagcagaa ggaagtattt gcaaaagcca
    29641 aagagtatac ccgttcccct gcagaaaaag acgatacaga tacacagtta ggtatcttaa
    29701 aaacatttga acgttacccg caagcggaag tcactttgat tggagctacg ggcggaagat
    29761 tggatcatct tttagccaat ctctggttag gtatggaacc tcgcttcaaa ccctttgccc
    29821 atcagcttat tatcagagat tgtcaaaatt atttgtctta ttatttgcct ggagagcata
    29881 tagtaagaca gataccagat atgaagtatt tagcttattg ctgcttgact cccgtctcga
    29941 atcttacatt aaaaggcagc aagtatgtat tggaaaataa agaagtagaa tatccgacat
    30001 cttatgcaag taacgaattt ctttcagata ccgcagaatt ttctttttca gatggtatga
    30061 ttgcagttat tcaaagcaaa gattgatcca taaacaaata aaaaaatttg tctttcaggc
    30121 taaaaatgac agaatctatt atttgctaaa aaaaagctta agaggagcaa cttacctttt
    30181 gtttcacggc atttagtgat aaaattgaac acaagagtct aattaattcg aggtgtcttt
    30241 gtgaagaagt tcaatcctaa taaaaatatt attattacct tggttattgt tatcatcgtg
    30301 gtgacgatac taagtgtgac cgctgcgcag cgagcgaatg aaggaaagcc caatttcttc
    30361 caatccatcg ttaatgacag tgttgcaatg gttgataaaa caatctctgc cccagtacgg
    30421 tgggtacgaa atggagtaga ttctgtccat aatctttttt caacttatgc cgaaaatgag
    30481 cggctaaaag aaaaaatcga tagctatgat gacgtttcac agcaaaacaa gaattacgag
    30541 agagaaatcg aagcgttgaa aaaagaactt gagttgaatc agacgctgac tagttacgaa
    30601 aaagtaacgg caaatgtcat tactcgttcg cctgacagtt ggcaggacat gctgatcgta
    30661 gacaagggtt ctaaagacgg tatcgaagca aatatggcag tcatgtcgca aaaaggattg
    30721 attggccgag tgatcgaggt caatacggct tcgtctaaaa tcgaattact gtcatcctct
    30781 aatgaaagct ccaatcattt tccagtacgg gtatcttcgg ctaatggcga agcgtttggt
    30841 ttgcttaaaa actatgatga aaagctccat gccttagtgg tgacccaatt aactggtgat
    30901 acggatatca aagaagggga tgttgtccag acatccggtc ttggagggaa ttctccagct
    30961 aacttgccga tcggtacggt tattaaaacg aaaccagata gttatgggct ggatcgggaa
    31021 gtttatgtga aaccttatgc agaaatgtat gacgtgtcag ttgtgacgat tgtccaacgg
    31081 ctagcggagg attagtccat gttgaagaaa gaaacaatga agtactatct gccaatcgtt
    31141 ttgttctttt tgatgttgat agatggtcat ttaacaagaa tgctagggga gtggtcgaaa
    31201 ggcacctata tgtcaaatgc ccactttctg atattggcat tattatgttg cagtatggcg
    31261 tttgaaaaac gttatttact gattaccacg attgttctcg gggctatcta tgacgcttac
    31321 tatattggcg ttatcggtat ctatgcagta gctctccctt taattgtatg gttgatgtat
    31381 gtaatgaaag acgttatcca tgtcaacatc tttactgaat ttttcagtat gatcatcttt
    31441 gtcacgggtt atgaattgtt tacgatggtg gtccagttga tttttaaatt agcagtagta
    31501 aataacacgt attttattac aaggttttta ggacctacac tgctgttgaa catgattata
    31561 tttgtattat tcatttttcc ctttaagaaa ttattcagtg atgaataatt tcttttttta
    31621 tttttaggtc gaaagcgaaa aagaatcgtt gttatcttaa gaaatgctag acttaacgcg
    31681 gctttttcat gatcattttc tgaaacgaac agttttgtca tttttaaaag ttgttttgaa
    31741 acatttttgt aacataacta ttatatcgtt gacacactgc tatggtacaa tttttatatc
    31801 gttaagaaag acttaaatat atttagatat ttattaaatt aagccagtcg gaggaatgaa
    31861 gagtgaaaaa gagtttaata tcagcagtaa tggtatgttc aatgaccttg actgccgtag
    31921 catcaccgat cgctgccgcg gcggacgatt ttgattctca gatacaacag caagatcaaa
    31981 agattgcaga cttgaaaaat caacaagcag atgcacaatc acaaatcgat gccttagaaa
    32041 gccaagtttc tgaaatcaac acacaagcac aagacctatt agcaaaacaa gatacattgc
    32101 gtcaagaatc tgcacaatta gtaaaagaca ttgcagattt acaagaacgt attgaaaaac
    32161 gtgaagatac aatccaaaaa caagcacgcg aagcacaagt aagcaacaca agctcaaact
    32221 acatcgatgc tgtattgaat gctgattcat tagcagatgc tattggacgc gttcaagcaa
    32281 tgacaacgat ggtaaaagca aacaacgact tgatggaaca acaaaaacaa gataaaaaag
    32341 ctgtagaaga caaaaaagct gaaaacgatg ctaaactaaa agaattagct gaaaaccaag
    32401 ctgctttgga atctcaaaaa ggcgatcttt tatctaaaca agctgatttg aacgtactga
    32461 aaacttcatt agctgctgaa caagcaactg ctgaagacaa gaaagctgac ttgaaccgtc
    32521 aaaaagcaga agctgaagca gagcaagctc gtattcgtga acaacaacgt ctagcagaac
    32581 aagctcgtca acaagctgca caagaaaaag ctgaaaaaga agcacgcgaa caagcagagg
    32641 ctgaagcaca agctactcaa gcttcatcta ctgcacaaag ctcagcaaca gaagaatcat
    32701 cagctacaca atcttcaatg actgaagaat catcatcagc tacacaatct tcagcaacag
    32761 aagaatcaac aacacctgaa tcttcaacag aagaatcaac agcgcctgaa tcttcagcaa
    32821 cagaagaatc aacaacagcg cctgaatctt cagcaacaga agaatcaaca acagtgcctg
    32881 aatcttcagc aacagaagaa tcaacaacag tgcctgaatc ttcaacaaca gaagaatcaa
    32941 caacacctgc gcctacaaca ccatcaacag atcaaagtgt tgatacagga aacggcacag
    33001 gaagtagtac tccggctcca acgccaacac caacacctga acaaccaaaa cctgtaacac
    33061 ctgctccagc tccttctgga agtgtgaatg gtgcagcaat cgtagcagaa gcttacaaat
    33121 atattggtac tccatatgtt tggggcggta aagatccaag tggctttgac tgctcagggt
    33181 tcacacgcta tgtttacatg caagtaactg gtcgtgacat cggtggttgg acagttcctc
    33241 aagaatcagc tggaacaaaa atttcagttt ctcaagcaaa agctggagac ttgttattct
    33301 gggggtcaca aggcggaact taccacgtag cgattgcttt aggcggagga caatatatcc
    33361 atgctcctca accaggcgaa agcgtaaaag ttggttcagt tcaatggttt gcccctgact
    33421 ttgctgtcag catgtaagaa tga
//
LOCUS       DADVXK010000020        32220 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.020, whole genome shotgun sequence.
ACCESSION   DADVXK010000020 DADVXK010000000
VERSION     DADVXK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.020"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(73..1014)
                     /gene="ribF"
                     /locus_tag="KB909_000886"
     CDS             complement(73..1014)
                     /gene="ribF"
                     /locus_tag="KB909_000886"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBB6836942.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(1018..1941)
                     /gene="truB"
                     /locus_tag="KB909_000887"
     CDS             complement(1018..1941)
                     /gene="truB"
                     /locus_tag="KB909_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBB6836943.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(2309..4671)
                     /locus_tag="KB909_000888"
                     /pseudo
     CDS             complement(2309..4671)
                     /locus_tag="KB909_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            5119..5292
                     /locus_tag="KB909_000889"
     CDS             5119..5292
                     /locus_tag="KB909_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6836944.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="KB909_000890"
     CDS             complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="KB909_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBB6836945.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(5823..8129)
                     /gene="infB"
                     /locus_tag="KB909_000891"
     CDS             complement(5823..8129)
                     /gene="infB"
                     /locus_tag="KB909_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBB6836946.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(8142..8453)
                     /locus_tag="KB909_000892"
     CDS             complement(8142..8453)
                     /locus_tag="KB909_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBB6836947.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(8450..8743)
                     /locus_tag="KB909_000893"
     CDS             complement(8450..8743)
                     /locus_tag="KB909_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBB6836948.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="KB909_000894"
     CDS             complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="KB909_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBB6836949.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="KB909_000895"
     CDS             complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="KB909_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBB6836950.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(10581..14939)
                     /locus_tag="KB909_000896"
     CDS             complement(10581..14939)
                     /locus_tag="KB909_000896"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBB6836951.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(15151..16860)
                     /locus_tag="KB909_000897"
     CDS             complement(15151..16860)
                     /locus_tag="KB909_000897"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBB6836952.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="KB909_000898"
     CDS             complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="KB909_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBB6836953.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(18357..19157)
                     /locus_tag="KB909_000899"
     CDS             complement(18357..19157)
                     /locus_tag="KB909_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBB6836954.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(19154..19966)
                     /locus_tag="KB909_000900"
     CDS             complement(19154..19966)
                     /locus_tag="KB909_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBB6836955.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(20161..20718)
                     /gene="frr"
                     /locus_tag="KB909_000901"
     CDS             complement(20161..20718)
                     /gene="frr"
                     /locus_tag="KB909_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBB6836956.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(20721..21443)
                     /locus_tag="KB909_000902"
     CDS             complement(20721..21443)
                     /locus_tag="KB909_000902"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBB6836957.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(21579..22460)
                     /locus_tag="KB909_000903"
     CDS             complement(21579..22460)
                     /locus_tag="KB909_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBB6836958.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="KB909_000904"
     CDS             complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="KB909_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBB6836959.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            23700..24179
                     /locus_tag="KB909_000905"
     CDS             23700..24179
                     /locus_tag="KB909_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBB6836960.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            24396..25487
                     /gene="phnW"
                     /locus_tag="KB909_000906"
     CDS             24396..25487
                     /gene="phnW"
                     /locus_tag="KB909_000906"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBB6836961.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            25480..25608
                     /locus_tag="KB909_000907"
     CDS             25480..25608
                     /locus_tag="KB909_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6836962.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            25612..26157
                     /locus_tag="KB909_000908"
     CDS             25612..26157
                     /locus_tag="KB909_000908"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6836963.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(26611..28302)
                     /locus_tag="KB909_000909"
     CDS             complement(26611..28302)
                     /locus_tag="KB909_000909"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBB6836964.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="KB909_000910"
     CDS             complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="KB909_000910"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBB6836965.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(29784..30803)
                     /gene="argF"
                     /locus_tag="KB909_000911"
     CDS             complement(29784..30803)
                     /gene="argF"
                     /locus_tag="KB909_000911"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBB6836966.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="KB909_000912"
     CDS             complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="KB909_000912"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBB6836967.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8581 a         6922 c         5724 g        10993 t
ORIGIN      
        1 ctgggcttat ttatcaccca ttttattgta attgctagtt atacataaac aagagatttt
       61 atgcataatg ttttattgct gagaaaaata ttcagctgtt gcttgttcat cctccttgag
      121 ttgttcaatc aattcctcta cactagaaaa tttcacttga tctcttaaaa attgattcca
      181 gcgtaccgcg acatgttcac catagatatc ttgattaaag tccaaaatat acaactctac
      241 agtcagctcc cgtccttcac cgaatgtatc attatgtcca attgaaccca tggctggata
      301 ccatgtttcc ccaattttta tttccgacac ataaacacct tctttaggca aatgaaccgt
      361 gctctttact ttgacatttg ctgtagggaa tcctagtagt ctgcctcgtg catcgccatg
      421 gacaactacc ccttctacct catatgtgca acctaatagt tttgctgctt cttttacttg
      481 tccgctgtct agtaatccac gaatacgggt agagctgatt ttttcacctt gttcttcttc
      541 tttagaaact gtgacgattt tgaatcttcc tttggcatat tcaggaaaat gagcgacatc
      601 tgcaatgtct tttggtccat acgtataatc aaaaccggaa acagcatatt ttgcatgtaa
      661 ccctacgatg tattgatcaa caaattcctg cggtgctaaa tgagcaaaag aagaagtaaa
      721 atcaacttca tataaataat ctatacccaa agcggccatt ttttcttctt tttgcttaag
      781 gctagtcaaa tatttcacgc tgctaggatc gatcttttta aagacaatag atggatgctg
      841 attgaaagtc atcaatgcta atttcaatcc ttctttttgt gcaatttcca tacctgtctt
      901 tatgactttc tggtgtccga tatgcacgcc gtcgaaaaat cccagcacta aaacgacatc
      961 gtcttctgga atttgttctg attggtaagg atgtctgatc ttgatgatat tcattcgtta
     1021 ttcctcattt ctcaatactt tactaggttt taatttgttt ttttctttcg ggtttggctg
     1081 ataaatactg acaacttttc ctttataaaa caaagcaatt tcttctgacg gcatttctgg
     1141 gagcgcaaat acagtataat caagtctcat accgtttttt actttctgcc atacttcatc
     1201 agtaatatct actcgtttga accgttccac tcctttttct attggcagca aacaatcatc
     1261 gattgtccca tttttcacag cttgagctac ttcttctaat gtcagagcat ccttctggga
     1321 cataccggca cttgctgttc gggtcagatc agacatgtgc gcagggtaac caagtttctt
     1381 gcctgtatct acagctaatg tgcggacata ggttcctttc ccgcattcta cttcgaagcg
     1441 ccaagaaatg gttcctgtca cttcgtctct tgtcaattca cttgtccgga taaaacggta
     1501 aatctgagcc tttctaacag gacgctccac tgtttcatta ttgcgggcat attcatataa
     1561 ccgcttaccg ttgactttta ccgctgagta cattggtggt atctgggtga tctcaccaat
     1621 aaatgaagcc atcacttcat ctattttttt ttcagataaa gacatatcta ctggttttgt
     1681 ttctacccgt tctccggatc gatcttccgt cgttgtactg aaacctagag ttatctcgcc
     1741 tacatagatt ttcccagaat ctgtcaaata ttcgataact tttgtggctt ttccaataca
     1801 aatgggcaac acaccgtcta cgtctgggtc aagcgtaccc ccatgtccga tttttttcgt
     1861 atgtaagatt tttcttaatt tgaatacgca atcatgactt gtcattccgc gttctttcca
     1921 taaaggtaat aacccgtcca tgtcttttct ccatttcatt tttgatttaa ctgaattatt
     1981 ataacacatt gcatcaatta ctgacgaatt tgacatcata atgaacggtt tttatttttc
     2041 ggcaataaaa acgtaacaaa attcatgctc acgtaaatag aaatcatgtt atgctttttt
     2101 aaaggaggga atagaatgga agattttttc tttgcaccat ttgattggat ttatgggtgg
     2161 cttacaggta aatagtttgg ttttcacttc ccaaaaacga aaaaaaagac tggccattct
     2221 tccagtcttt tttccgtttt ttttatttat tttttcagtt tcttaatcaa tgtaaaaaat
     2281 tctattttgc gggatcgatt ttatcatttt attggtcaag atttttccat ttccaatcca
     2341 atacttctgg cagatcaata ccattttcac gaatatagtt ttgatgttct tgtaatttct
     2401 gatccatttt tttcgcaaaa tcttctgctt gacttccttt gatttttaaa gctgcgtctt
     2461 ttgccaaatg ataacgatca agttcattta ctacacgcat gtcaaatggt gtcgtgatat
     2521 ctccattttc tttgtagcca tgaatcatta aatgatggtt atgacgatca aagaaaatcg
     2581 tgcggaccaa tgtttcataa ccgtggaaag caaataagat cggtttgtct tttgtaaaat
     2641 attgatcaaa ttcttcatcg ctcaacccac gcggatcttg acttggatga cgtaatttca
     2701 ataaatctac gacattgatg aaccgaattt ttagttttgg gaattcttcc agcagcaaag
     2761 ttacagctgc taatgcttct aagttagatt ccgttcctgc agcagcaatg accaattcag
     2821 gttcctcctc ttttgctgtc gaagcccaat caatgatttt caagccttca ttcactaaga
     2881 cggctgcttc ttctgctgag taaaattgag cacgcggatg tttggaagag atgatcaaat
     2941 tgattttttc tgacgagcgg aatgctttat ccatgactgc gagcaatgta tttgcatccg
     3001 caggcagata ttcacggatg aactccgcct tcttttctgc caaatgtgtc aatattcctg
     3061 gatcttggtg gctatatcca ttgtgatctt gctggaagac tgttgagctt gcaatgagat
     3121 ttagcgaagg ataatcattt cgccaagaaa ggtcatgtga tttccgcatc catttgaagt
     3181 gctgagtcaa catagagtca accactcgca agaatgattc gtaacttgca aaaaaccatg
     3241 ccgtccagtc agaacgtacc cttctaagaa cccttcatct tggtgttccg ataattgact
     3301 gtcgatgacg cgaccagatg gcgaaagcca ttcatcattt tctggttcga ttttttccat
     3361 ccattggcga tttgtcgttt tgaaaacttg attcaatcgg tttgattttg tttcatctgg
     3421 tccaaatata cggaaatttt ctggattttt ctcaatgatc tcgcgaacga atttaccaag
     3481 ttcggtcata tcttctgctt taacggagcc tggtttttca aattgcaaag tatatttttt
     3541 ccaatctggc ataataagcg gtcttggatc gattccacca ttggtgatag gattttttgc
     3601 cattctttgg tcaccagtag gcgcgatttc tctgatttct tctaaaatac gtccttgtgc
     3661 atcaaataat ttttctggtt cataggattt cagccaacgg agtaaagcat ctgcatgatc
     3721 catatgttct tgatctacag gaatcggtac ttggtgtgct cggaaggttc cttcaattgg
     3781 ttccccgtcc cattcttttg gaccggtcca tccttttggt gtgcgtacga tcaatactgg
     3841 ccattttggc atcacgacat ctgttgctgt cttcaggcga gcttcttttt ggatggattt
     3901 aattttctcg attgcttgat ccattttttc agccataaca ggatttaatt tttctgaatc
     3961 atttccttca ataaagaaag gttcccagcc aagtccgtta aagtaatttg ctaattctcc
     4021 atctgattta cgtgccaaga tcgttgggtt ggctattttt gcaccattta aatgaaggat
     4081 cggtaaaaca gctccatcta tcactggatt gataaagaca tttgagaacc agcttccagc
     4141 taaaggaccg gtttctgctt caccatcacc aatcacgaca gcagagatta cttcaggatt
     4201 gtctaataca gctccgactg catgtgaaag agagtatcca agctctccgc cttcatggat
     4261 agaacctggt gtttctggtg ctgcatgaga agcaatgcct ccaggaaatg aaaatcgttt
     4321 gaataatttt tgcattcctg tctcatcttc cgttacttct ggatagatct ctgtgtaact
     4381 tccatctaaa taagcattcg ataccatgac ttgtccgccg tgtcctggcc cttcaatata
     4441 aaacatgttc aaatcatatt tattgatgac tcggttcaaa tggacataaa taaaattttg
     4501 gccaggaatc gttccccaat gaccgattgg atgttttttg acatcttcgg gtttcagtgt
     4561 acgtctcagt aaggggttat ctttaagata aagttgccca acagaaagat aattagcagc
     4621 acgccaccaa gccgtcattt tatcaaagta ttctttacta gaataatcca tacataacac
     4681 tccttttcat tattactctt attctagcgc agatactccc aattgaaacc taataagcac
     4741 ttctgttcat ttgtttggat tttatatcta gccaaatgaa caggtataaa aaaccacgaa
     4801 atttttcctt tcgctgacgt tttttacatt gatccaaaaa acttgtcgtt atcacaatgg
     4861 ctgttccgca gttcatttcg ctcctcatca tgcataattt gctgaatgac gctgggccag
     4921 ttaacacatt gctggaaaac tggggctgga tcgagcaatt cctttcctga ttgatccgtt
     4981 ttatgtaaaa gtctctgtta tctttgtcaa tatgtgaatt ggtatcccag ctactatgct
     5041 aatttctaca gggattatcc aaaatttgga tcgtgaccaa atcgaagcgg cgtaatcgga
     5101 aatatcaata acttcaacgt gatttttctt ttaactgtca acggaccgac aaactcaaac
     5161 ttttatggtg caggttccac tgatcttcta gttacttggc tatacctgac tgtcactaaa
     5221 atagattaca atctagcttc cgttatcggt atcttgatct ttatctatat gcaaaaattt
     5281 atatactact agaaaaaaga aagtcgaatt ttttactttt ctttttctct tttttggtta
     5341 gctgacacgc cgcaagacta aagtcatgga actcttaggt aatacgtctt aatgaaaaca
     5401 aaaaaatccc gcaacccctg atttcacagg atttgcggga gtttttgatt agtctttgtt
     5461 caagtcgcga agcaattcat cgatatggtt gccatagaca actgattcat caagttcaaa
     5521 gaacaattca ggtgtcttat aaatacttag attgtgccct aactctcgac gaatcaatcc
     5581 tgatgcttta ttcaatccat cttgtgctgt tttcttatct gatgctaagt cagataaaat
     5641 gctgtaatag atcgttgctt gctgtaagtc ccccgtaact ttcacatctg tgatcgttac
     5701 gttctccaca cgagggtcac ggaccttttt gcgcaaaata tcattgactt cttttaagat
     5761 ttcttgaccg actcggcggt cacggtagtt agccataatg attggcctcc ttttatcagt
     5821 ttttagtcat ttttgacttc ttccatgata aatccttcaa ttacgtcatc tactttgatg
     5881 tcattgaatt tttcaatcat tgcaccacat tcataaccca ttttgacttc tttcacgtca
     5941 tctttgaatc gtttcagact tgcaagttgg ccttcataga ttacgattcc gtcacggatt
     6001 acacggacac cgctatctct acgaatatat ccttctgtta cataggcacc tgcaatcgta
     6061 ccaactttag aaactttgaa ggtttcacga acgatcattt gaccggtgat tttttcttca
     6121 aattcagggt ctagcatccc tttcatcgca gtttcgattt cttcgatggc tttatagatg
     6181 atacggtgaa gacgaatatc gacttcttca gtatcagctt gcacttttgc ctgcggtgta
     6241 ggacgaacgt tgaaaccgat gataatagcg ttgctggctg ctgctaaggt tacatcactt
     6301 tcattgattg ctccgacagc tgaatggacg atttttacac ggacaccttc cacatcaatc
     6361 ttcttcaatg atgcagccag tgcttctgct gaaccttgta catctgcttt gatgattacg
     6421 ttaacttctt tcaattcgcc ttctttcagg ctttcaaata agttatccaa agtcacacgg
     6481 cttgtggcag cacggttttc taataatgca cgtttcgcgc gttcttcacc cgctgcacgt
     6541 gctgtctttt cgtcttcgaa gactacgaaa cggtcacctg cttgaggtac atcattcaag
     6601 ccagtgattt ctactggcgt tgcaggtcct gcttctttat cgcgacggcc aagatcgttt
     6661 gtcattacac ggacacgtcc gtaagtatta ccgacaacga ttgggtcacc aacatgaagt
     6721 gttccttctt ggacaagtaa ggttgacaca ggacctttac ctttatcaag acgtgcttcg
     6781 atcactgttc cgattgcgcg ttgtgttgga tctgctttta aatcttctac ttctgcgact
     6841 aacaggatca tttccagcaa ttcttcgatg ttttggccga atttcgctga gatctcaaca
     6901 aagatcgttt ctccacccca tgcttcagga attaactcat actcacttaa ttcttgcata
     6961 acatgttgag ggtttgcacc tggtttatca attttattta cagcgacgat gattggaacg
     7021 cctgcagctt tggcatggtt gattgcttca actgtttgtg gcatgacgcc atcatctgca
     7081 gcaacaacta agatcgtgat atctgtgata cttgctccac gtgcacgcat acttgtaaag
     7141 gccgcatgtc ctggtgtatc caagaaagtg attggtttac catcaatatc gatctggtag
     7201 gcaccgatat gctgtgtgat tccgccggct tcgccgcttg ttacacgtga atggcgtaat
     7261 gtatccaata aagttgtttt cccatggtct acgtgtccca taatcgttac gactggcgga
     7321 cgtgagacta atttatctgg atcgacttct tctgcctcga agaatttatc gatatcagca
     7381 atgtcaactt ggactttttc ttgtggttcc atgccatagt ccgtcgctaa cagttcaatc
     7441 gtatctttat ccagtgcttg gttttgattg accatgacac caagcataaa taatttttta
     7501 atgatttctg ctggctcacg atgaattttt ttcgcaatat ctgctacgtt cataccttca
     7561 gtatactcta atacatctgg caattcacgg aatttgcgtg gtggtacagc tggtttagtt
     7621 gattgttgct gtttgccttt tttacctttt ttattataac gattacggtt attattatta
     7681 aatttgccgc gattgttatt gtttggtttg ttgttattgt tagtacggtt ttgattgccg
     7741 ccttggctcg ttccttgacg attttggctg ctggtatttc ccgtattatt ttggtttgtt
     7801 gttggttttt ttccttgatt cacttgaccg ctcccttgac cgcgatcttg ataactgcgg
     7861 ttatttttat ttttttgttg attgttcgtt gtttcttttt tacgttgatc gttcggctgt
     7921 tgattggctg gttttctgct tgcttgttgt gcagcttgtt gtttcgtgct tgggtttttg
     7981 aacgcttgtt gcaatttctt ctcatcattg ctagtaatcg cacccatatg gtttttcaca
     8041 tcgatgccaa gttgttgtgc tttttccacg acgtctttac tagatttttt gagttctttt
     8101 gctaattcat agattctttt gttgcccatg caatcacctt cctaaccttc aattagctcc
     8161 ttggtcttct tcgcaaatcc ggcatccatt attccgaata ccttgcgagg ttttccgatc
     8221 atctgcgtga tttctgcttc agaaaatagc tcaaagcaag gaacttcata atatgaactc
     8281 ttatctttta tcttttttct tgtattctcg cttgcatcgg ttgccacaaa caccaatttt
     8341 gctttttgtt tgcggatttc agcaatggtc agttcttcac ccgtgattag ttttcccgcg
     8401 cgcatcgcta gaccgatgag attcatggct ttttgccgat taactgtatt cattttccaa
     8461 ataactcttt acgtgctttt tggtgagtga catagtcaag aagttcttga taaaactcat
     8521 ctgttaatgt tgtttcgagt actcgatcga gaattttttt atcccaagct tgttgtactt
     8581 cttccggctc aagtgagaca tacgctcctc gtccaggcat ttttccagtt ggatcgatcg
     8641 atacttcccc ttcttttgaa cgggtgattc ggaccatctc ttttttaggt ttcatttcac
     8701 ctgaaaccac ggatttgcgt aaaggaattt tcctttgttt catctctttg cctccttact
     8761 aaagttaagc ttctggtttt tcttcgaccg tttcattgtt gaatgcaatt gtttcatatt
     8821 catcgtctgt taaatctgac tgaacgattg cttcatcatg cagttcttct gtttcttttt
     8881 gttgttcttg attttcataa aattccgtca tgtcagattc tgatttgata tcgattttat
     8941 ggttagtcaa tttagcagct aaacgtgcgt tttgtccgcg tttaccgatt gctagcgata
     9001 attggtagtc tggaacgaca actgtgcagg cctttggatt tgtctcatcg aagatcacat
     9061 ccatgacttg tgcaggattc aatgcatttg caatgaatac agctggatct tcattccatt
     9121 cgacgatatc catgttttcg ccttttaatt cattgacgat tgcttgaact cgttgtccct
     9181 ttggcccgac acatgtaccg actgcatcga tatttggatc atttgagcga actgccactt
     9241 ttgaacgatc gccagcttca cgggcgatgc tgacaatttc aacgattcca tcatagactt
     9301 ctggtacttc ttgctcaaat aagcggcgca ataggtctgg atggctgcgg ctaacaaata
     9361 cttgcggacc tttagacgta ttttctactc gggaaacata aactttgatt cgatcatgtg
     9421 gttgataaaa ttcatttggc atttgatctt gtttagaaag aactgcctca attttaccaa
     9481 gattgacata aatataacgt ttatcctggc gttcgacgat tccttgcatg atgtcttttt
     9541 cataagcact gaattcgtta taaataatcg ttctttctgc ttcacgtaca cgctgtaaaa
     9601 taacttgttt agccgtttgc gcagcgatcc gcccaaaatc ttttggtgtt acttcaaaac
     9661 ggatcgtatc accgatctca tatgctggat tgattaaaag tgcatctttc aatgagactt
     9721 ccaactgtga atccatcact tcttccgtta cttcttttac cgcatagaca tggatctttc
     9781 cttttttctg atcaaattcc acttcgacgt tttgtgcttg gccatagtga cgtttgtatg
     9841 cagaaaccaa tgctgcttct aaagcatcga tcacgatttc ttttgagatc cctttttcag
     9901 cttctaaagc gtctaacgca tttaacattt ctttactcat tttttctgat tcctctccgt
     9961 gattaaaatt ggatagctaa gcgagctttt gcaatatttt ttcggtcaaa agtcaattct
    10021 ttttctcgtg tttttatgcg tattttcaat gtaagctgtt cagcatcaaa tgattgaaga
    10081 aatccttcat attgtttttc gccatctact ggttggtata aggagacatg gacataatca
    10141 ccaagtgcct tttcatagtc gctttctttt ttcaatggcc gctctgctcc cggggaggat
    10201 acctccagga aataagcttg aggaatcgga tctggatctg ctgcatcaag tttttcactc
    10261 agtttctcac tgacaaaggc gcattcttcg atatcgatac cgccttcttt gtcaataaat
    10321 actcgtaaga accagctttt tccttctttt acaaattcga cttcgacaag ttcaaaattt
    10381 tgttcatcta aaatcggtgt caccatttct gtgactgttt caacgacgct actcaaaagt
    10441 ttcgcctcct taaaaaatta agtgcgtaat tccattaaaa agagtgagcg aaaaatccgc
    10501 tcactcacag ttagtatcat tacctataag aactatacca tactctgctt aaaattacaa
    10561 gcagacagga aaacagatgc ttatagcata tcgaataacg ataattgatt ttcatctggt
    10621 agatctttca atacgccatt gtcgttcata tattcgatca atgtttttga aactttaccg
    10681 cgggtggcaa gatcttcttt ggataaaaat ggaccgtctt ttcttgcttc aacgatttgt
    10741 tttgccacgt tggttcccaa acttgggaca gctctaaatg gtgcgatcaa cgtatcacct
    10801 tcaataacaa agttaacggc atccgattta tacaaatcaa tcattccaaa tttgaatcct
    10861 cgttccagca tttcattggc taactccagc actgtcagtt gattcttttc ttttacggaa
    10921 gcatctaatc ctttgtccgt gatttctttc attgcttgtt tcacagcatc ttttcctttg
    10981 cacatggaga ctagatcaaa gtcgtctgca cgtacagaaa agtatgcaca gtaatacaaa
    11041 atagggaaat aaaccttgaa ataagcgaca cgaagagcca tcaatacgta agctgcagca
    11101 tgggctttcg gaaacatata tttgattttt gaacaagaat cgatatacca gtcgggcaca
    11161 ttattttctt tcatcgccga tagataggtt tctcgcaatt catcagggat cttgttccat
    11221 tgtcctttac gaacagtttc catgatttta aatgccatcc cgctatctaa tccagcatgg
    11281 atcaaataaa ccataatatc atcacgacag ccgattactt ccgccagtgt cgcatctcct
    11341 cgtcgaatca attcttccgc atttcctaac catacgtctg taccatgaga tagtccggaa
    11401 atttgcagta gttctgcaaa agttgtagga tgcgtttctt ctagcatccc tcgaacaaaa
    11461 cgagtgccga attctggaat acctaatgtc cctgttttgg aataaatttg ttcctgactt
    11521 actccaagta cttcaggacc ggcaaatatc cgcatcactt ccgggtcatc cgtagggatc
    11581 gtttgtggat cgatccctga taaatcttga agcatccgaa taacagttgg gtcatcatgc
    11641 cctagaatat ctaatttcaa tacattatcg tgaatcgagt gaaaatcaaa atgagtcgtt
    11701 ttccattccg aattttgatc gtctgctgga tattggatcg gcgtaaaatc atagacatcc
    11761 atataatcgg gaataacgat gatcccccct ggatgctggc cggttgtccg tttgactcca
    11821 gtagcgcctt ttgctaatct gtcgacttct gcacttcgaa actgcagatt attgtccctt
    11881 tcgtatcctt ttacatagcc atatgctgtt ttgtcggcga ctgtaccaat cgttccggca
    11941 cggtaaacat agtcttcgcc aaacaatact ttcgtatagt tatgggcttc tgcttgataa
    12001 tcacctgaga agttcaaatc aatatcgggc actttgtctc catggaatcc taaaaatgtc
    12061 tcaaatggaa tatcatgacc gtctttgttt aagcgtgcac cacattttgg acattgtttt
    12121 tctggcatgt caaatccaga accatacgta ccatcttcaa aaaactcgga atattggcac
    12181 tctggacaat aataatgagg ggctaacgga ttaacttcag tgattcctgt catcgtcgca
    12241 acaaagctag agccaacaga gccacgtgaa cctactagat agccatcttc attactttta
    12301 tgcactagtt tttgggcgat cagataaata accgagaagc cattaccatt aatagaattc
    12361 aactcttttt ttaatcgttt ttgaatgatc tcaggtaacg gatctccgta catttgtttt
    12421 gcttttgtgt aactcaattc tgatatttca tcttctgaac ctggaatctt cggtgtataa
    12481 agttcatctt tgactggaat cacttcttcg cagatatctg cgattttatt cgtattttct
    12541 actacgatct ctttcgctgt ttcttcccct aaaaagtgaa atgcagttag catctcatcg
    12601 gttgttcgga aatggacatc cggcaaacta tgacgattca acggattcgc tccgcccata
    12661 gaattgatca aaatttttcg gtaaatggca tcttcttcgt tcagataatg tacattacct
    12721 gttgcaacaa cgattttatc caaacttttt ccgatttcta ccaaattttg gataatttct
    12781 tccaaatcat gttcattttt taccaattct tgctcgatca aaggcgcata gaccgctttt
    12841 ggcataactt caatataatc gtagaatttt gctcggtttc ttgcctcttc tacccctttt
    12901 tgcatcatgg cttcgaatat ttctccctta tcacaagctg agccgatcaa tagattttca
    12961 cgcatctttt tcaattggga gcgtggtatt cgtgggacgc gttcgaagta ttcgacattc
    13021 gacattgaaa tcagtttgaa caaatctttc agtcctgcct gattttttgc taaaatcgtt
    13081 acatggaaag gtcgagccct tttgtaagaa tctccttctc cgatatgctc atttagctga
    13141 tcatgataaa gcatgttatg attgtccatt gcctctttca caaagatcca tgctaagtga
    13201 ccagttgctt cagcatcata gattgctcgg tgatgctgtt ccaagctgac accaaatttt
    13261 ttagataaca cacctaatcc gaaacgtttg aattgaggat acagatatct agctaattcc
    13321 aacgtatcaa tgactggatt ggccgcttca ggaataccat accttgcgta gctagtattc
    13381 aagaacccca tatcaaaagc cgcgttgtgg gctaccaaaa ttgtatcttt tgaaaattca
    13441 aggaacatcc gcaatacttc ttcttccgac tttgatcctc gaaccattcc atccgtgata
    13501 ccagtcagat ctaccgttgt tcgtgacaaa ggatgtcctg gatcgataaa ttcatcaaag
    13561 ctttcgatca catttccttt atacattttg actgcggcta gctcgatgat cgtgtcatat
    13621 actgcagaca atcctgtcgt ttccacgtca aatacgacat atgtggcttc actcaatgct
    13681 tcatgtgcat cattataagc aattgggaca ccatcatcta cgacattcgc ttccacgccg
    13741 tataagattt tcacacctgc tttttttcca gcactatgtg cttccggaaa ggcttgcgca
    13801 ccaccgtggt ctgtaatggc gatagctcgg tgtccccatt tccctgcttg tgccacaaga
    13861 tcagagatgc tgtttgttgc atccatcgta ctcatattgc tatgaacatg aagctctact
    13921 cgtttttccc cttcaggagc ataatctttg cgaggtgtat gtttgacttc tatgatatct
    13981 tgcgcattca tgaccaaatc acggacaaac gtatcttctt gaatacttcc tcgtaccttt
    14041 aaccagctac cgacactgat cgcatcaaat acttgttcat ctttttcgcc gttcgagaat
    14101 tttttgacga taaatgatga agtataatct gtgattttca aagtcaagat cttgcgtttt
    14161 gaacgtagtt ctctgacttc tttgtcgaat acgtacccct caagtgtgac tcttcgttct
    14221 tcttcaacga tactgatcat tggtgtcgtt ggttcatcgg ctggaatatt tcgtcctagc
    14281 tggatgtgga tgggtccttc aagagctggc gattgctctt ttctttcctt tttcttttgt
    14341 tcgtggacaa ctagactttc agctgcttgc ttcataaagg cttctgcctg ttcttgtttg
    14401 cgttcttcaa aaagtttcaa tactcgttcc gcttgctgct catccacttc tggttcgata
    14461 cgaaattttg ggaatccgta actgacgaac aactcttcta ctaatggcaa gtattgttgc
    14521 ttcaaataag aaatagctcc tgtactgtcg attggcaaga tgactttacg atcttttatc
    14581 acaggtacct gcgttttcaa tacttgctgt gctagtggtg tatcgcattg ctgattttcc
    14641 aaagcttggg cccagtaatc ttgcaagagc tgttcatcga atgtctggtc atctgctaag
    14701 atattcagtt tgacttgtgc aatatcttta aaagcgatag tcagatgctg agtcaatgac
    14761 cgatatagca taataggcaa aattttggaa aaatgcagcg taaattccca taaacgcgat
    14821 ttacgatgga ccactacact atccatttca ccagcagtaa gcagtggatg atttttttct
    14881 gcttcctcta gttggatttg ttccaacagt ttttcaaata aatctcgttt ttctgacaaa
    14941 gatatacgcc ctttctgatg agaaacaatg caattgatcg catcttatcc tcttcttttt
    15001 cagtaccttt tagtatactc gttttttctg agttttacat taaaaaattg gaactgcgat
    15061 tcaaatcgca gttccaattt taaaagcgaa tcatcagatt gtcaaaaaca gctgattcag
    15121 ctatttttat tttctgtgtt ttaacgctta ttattcgcct tggttcaaga ggattggtaa
    15181 agtattcacc aattcttctt tacgtacttc aaccatttcg ccagttttct tgattttcac
    15241 ttctacgatt ccatccactg cttttttacc gacagtgatt ctgattggac agccaatcaa
    15301 atcagaatcc gcgaatttca ctcctgcgcg ttcatttctg tcatcaacca gtacttcata
    15361 gccagctttt gtcatcgctt cttctagttc attcgtcagg tttgtttggt attcgtcttt
    15421 tagattcatt tggacgatat gcaaatcaaa tggcgcaatt ccttttggcc agttgattcc
    15481 ttgttcatct gaatgttgtt ctacgattgc tgataataaa cgacttacac cgataccata
    15541 acagcccata atcacaaatt tttctcgtcc attttcgtct agtacagttg ctcccataga
    15601 ttcactgtaa cgagtgccga ttttgaagat atgtccgatt tcgattcctc gagtaaaggc
    15661 aagaacacca ttgttgtctg gtgaaggatc tccttcttgt acaaaacgaa gatcttcata
    15721 agaaagtaca gtgaaatcgc gttctggatt cacattttta tagtggaatc ctgtttcgtt
    15781 cgctccagta atggcattcg ctaaatcttg gacataacgg tctgcatata cttttacgtc
    15841 atctgaaaca ccgactggtc cgacagaacc aaactcagca cctagatatt tttgtgcttc
    15901 ttcttctgtt gcttcttcta aaaagtcagc agataaaaag tttttcagtt ttacgtcatt
    15961 gacttcatgg tctccgcgta ccaaaacaag gacaggttgt tcatccgcaa tgaacaatac
    16021 agacttgatg attttttgag gttcaacaga aaagaaatct gctacttcgt caattgattt
    16081 tacgttaggt gtagctactt tctccaattc aagctgtgtt tcatgcgatt tttttgatac
    16141 atagtagctt gtagccatct ccaagtttgc agcataatca ctttcagtcg aataacagat
    16201 cgtatcctcc ccgatttctg agatcgccat gaattctttt gagtctttcc cgcccattgc
    16261 gccaccgtct ccgataatcg agcgaaattc taagccacaa cgcttgaata cttcggtgta
    16321 ggctttttcg taatctttat atgtctcgtc caaactttct tccgttgcat ggaaagaata
    16381 cgcatctttc atgataaact ctcttccgcg aagcaaaccg aagcgaggtc gtttttcgtc
    16441 acgatattta ggttggattt gataaagatt taaaggtaat ttcttatatg aattgatttc
    16501 attacgcatc aaatcagtaa aagtttcttc gtgagttggt ccaaggatca tttttcgatc
    16561 attgcggtct ttgaaacgat acaagtttgg tccatatgtt tcgtaacgcc cggattcttc
    16621 ccaaagttct gctggcaaga tggcaggcat cagcatttct accgctccga ttttttcaaa
    16681 ttcttcccgc ataatgcgtt tcagtttttc caatacacga tttgctaatg gcagatatga
    16741 ataaataccc gctgatactt ggcggatata tccagctctt agcaagattt gatggcttaa
    16801 tacttctgca tcatttggaa cttcgcgtaa tgttggaatc aacatttttg attgtctcat
    16861 tctatatact cctttatttc ctcaaaatag ttatcgtttg ttattatacc ctatttgtca
    16921 actttttcta gaaaaagaat cgttgaatat cgttccatgt aactagcacc atcaacaaca
    16981 ttaaaaatcc aaagccagct aatgtcaata ttccttcttt ttcttgactt aatggtttcc
    17041 cgcgaatccc ttcaaaaata ttcaagacta atttcccgcc atctaaggca ggaatcggaa
    17101 gcagattgac gattccgaga ttcattgaaa gaagcgccat caaactaata acagttgtta
    17161 caccttgatt tgctgcttct gaagacaatt ggtacatcat gacaggtccg cctaatttat
    17221 ctaaactgaa acctgtaaat agtgatccta aggctttgaa aatttccaat gaaccgctga
    17281 aagcttgacg cgtccctcca atgatcttat ccataaaacc tgtattcatt ggggctttta
    17341 taccaagttg gccaactttt tcgccatttg actctacaga tttcggtgtc acgtcgacag
    17401 attgcacctg accttctcgt tcgatcttaa agtctaatgt tttatccgga tttttcgtaa
    17461 tgactgttgt cagatcattc catgaatgga tttcttttcc gtccacactg actacctcat
    17521 cattttcttt taagcctgct tctgccgcag ctccattagg catgatctct cctacgcgat
    17581 tagtgttcgt cacttgaaca ccaccttgca taaatgccag aatgatgaat aacaggattg
    17641 ccaaaataaa gttattcatg ggtccagcaa agttggtcag catacgctgc cacaatttag
    17701 ccgattggaa ctgtacgtct tttggcgcaa ttctgatttc tgttccgtcg ttttcaataa
    17761 tcgtcgcatc gtgatcaaca gggtaggtta ctacttctgt ttcgtctcca ttcacataac
    17821 cagtgatagt cagctcatct tctaaatcat aacggctcaa ttccatcggg atagcatttg
    17881 tcaattggat tttcttactt aaatttatct tctctacgat gccgtcagaa tttagtaaaa
    17941 gagaaagagg cattcctggt gccatttctg tttcatcatc cccattgcct gccattcgaa
    18001 cataaccgcc aataggtaat aggcgaagcg tatatgttgt cccgtctttt gcttgatgcc
    18061 cataaatttt cggacccata ccgatagcaa attcgcgaac gaggattcct gatcgtttcg
    18121 caaagaagaa atgaccaaac tcatgaacaa tcactaatat accaaaaacg atgataaatg
    18181 tcagaatcgt tttcatagct tttttctcct ttacttgttt tttgtgtttt ttataaaaca
    18241 acgataaaac actataattt taccatagta taccaaagac accaatagta tcaatataat
    18301 gaaaaataaa aacctgcgtc ttttatgaaa ttcacaaaga aacgcaggta tacttactaa
    18361 ataatgccaa ataaatgcat gataggaaat acaaacagca aactgtcgaa acggtctaag
    18421 attccaccat ggcctggtaa gatatttccc gagtctttca catcataatg acgtttgatt
    18481 gcagattcga ccaaatcacc aaattgtccg actgctgaaa aaataatcgt catcagaagc
    18541 atgacaaaca taccatgatt aaatagttct tttgctgggt atagcaataa ataaagaaat
    18601 gcgactacaa cagcactacc aataccaccg agcgcacctt caatcgtttt gttgggcgaa
    18661 atatcaggac ttaacttatg ctgaccataa cgtcgaccaa ccatatatgc tccgatatca
    18721 gttgcccaaa caataaatag accaaatatc aaaacagcca agctttctgt tcgtgcattg
    18781 acaaaattct ggaaacctat tcccacatac aagctgacaa gcacaggaaa acctgcttca
    18841 tcaatcgtat acgtattttt agaaataact gatgttccta aaagaatcat aactataaga
    18901 taaaataaca taaatgtact tacattctct ggaagaaaga aaaaccatct ttcttttggc
    18961 aaaacaagta acactgcacc aacggcggat aaaactcctt caaaacttaa gagtgtcaat
    19021 cctttcatcc gaaacagctc gtaaactcct attactgcta agattgctgc tgtaagctca
    19081 accgctatgc ctccgatcca tataatcgga ataaacaaga ctagcgccac ggctgctgtg
    19141 accacacgtt gtttcatgac tgatcccctt tctcatcttc tgtttttttt acaccgccga
    19201 atcgacggtc tcgattttga taagaggcga ttgcttcttc aagatgcgca ccatcaaaat
    19261 caggccaaag cgcttttgta aaatacagct cactatatgc gatctgccat aacagaaaat
    19321 tactaattcg ctcttctcca cttgtacgga tcatcagctc aggatcttgt aactctttag
    19381 gcaagaaacc tgtcattaaa tgcttagcaa tcaattcatc atcgatttct tctgcgtgta
    19441 tttctccttt tgctacttct tcggcaattt cttggacagc agtcacgatc tctgctctgc
    19501 ttccataatt caaagcaaaa ttcaatacca ttccagtatt gttttttgtt tgctcaattg
    19561 cacgtcttac agcatcttgc gtatgttctg gcaatacgtt ttcataaccc atgacatgaa
    19621 ctttgacatt ttctttaatc aattctggta cgaacgtatc aaagaagtcg acaggtagtt
    19681 gcatgagaaa acttacttca tcttttggtc gcttccagtt ttcagtcgaa aaggcataaa
    19741 gcgtcaacac tttcactcca agccttgatg ctttttttgt gactttcttt actgtttcca
    19801 tgccttcttt atggccagca actcgtggca aacgacggtt ttgcgcccaa cgaccattgc
    19861 cgtccatgat gatggcaatg tgctgaggaa ttggtccatc ggtattaaat tgaaattcgc
    19921 ttttttcttg aatatatttg tttttttgcg gaaaaaaacg taacattctt tttcctccta
    19981 tacttaaaag attcccacta tcttaagtat tatagcaata tctaactgtt tttcctatga
    20041 aatcattgtt tttttattta aaaactgaat aattttttct ttttttaatt tttaaataaa
    20101 agaaatataa ataaaaacag aggaagcgga atgatccgcc cctctgtttt tatgatttta
    20161 ttaaacttcc aataattctt tttctttatc agcagcgatc ttatctactt ctttgatgct
    20221 gttatctgtc aatgtttgta cgtctttttc taatccgcgc aaatcatctt cggtaatatc
    20281 accatttttt tgttgttttt tatattcatc gatcgcatca cgacggatgt tacgaatcgc
    20341 gatttttgca ttttctgctt cttttttaac atctttagct aattcttttc tgcgttcttc
    20401 tgtcagttgc gggataacta agcgaatgac atttccatca ttggttggac tgattccgat
    20461 atcacttgcc ataatagctt tttcaacatc ttgaagaatg ctcttgtcaa aaggtgtgat
    20521 cattaaaaca cgtgcttctg gaatttggat tgatgccatt tggttcaatg gtgttggcgc
    20581 accgtagtag ttcacagtaa tacggtccaa aaggctagcg ttcgcacggc ctgcgcggat
    20641 ttgcccaagt tcacgttgaa gattttgtgc tgcttttttc attttttctt ttgcttctgt
    20701 cataattgca tctgccattt ttatttcccc cttacagttg ttccgatatt ttcgcctaag
    20761 attgcacggc gaatatttcc gtgttcattt aaattgaaga caagcagtgg aatatcatta
    20821 tccatgctta gtgaacttgc agttgaatcc atgacttgta atcctttggc aataacttcc
    20881 agatgagtca gttcttcaaa ttttactgca tttgcatcta ctttcggatc agcagaataa
    20941 acaccgtcta cattgttttt agccatcagg ataacatctg cgccgatttc tgccgcgcgt
    21001 aatgctgctg ttgtgtctgt cgagaagtac gggttgccgg taccgcctgc aaagataacg
    21061 atccgtcctt tttctaaatg acgttctgct ttacggcgaa tatatggctc tgcgatttga
    21121 cgcatttcaa tcgaagtttg cacgcgtgtc ggtacaccca cgttttccaa cgtatcctgt
    21181 aaagctaagg cattcataac tgtagctaac atacccatgt aatcagcttg agcacgttcc
    21241 atgcccattt gtgctccgat ttgtccgcgc cagatatttc cgccgcccac aacgattgcc
    21301 atttcaacgc ccagctcgtg aacttctttg atttcttgga tgatttcttt gattactggt
    21361 ggtttgattc caaatcctgc gtccccagct aaagcttctc cactcaattt taagactaca
    21421 cgctgatatt tcggtgtgac catgttcatt cctccaatat tttctattgc cattttacca
    21481 tacttagatg atttcgacac tctaagactg gtttttcttg ttttgcttaa aaaaagggag
    21541 cgcacaaacc gtgcgttccc gtctgttatt caacagaatt attttttcac ttggctcata
    21601 acttcttcta caaagttatc ttcgcgtttt tcgatacctt cgccaacttc gaaacgtacg
    21661 aatgttttaa cagttgcgcc ttttgatgca acgtattttt caacagtcat atcaggatct
    21721 ttaacgaatg gttggtccac caaagcgatt tctgctttga atttcttcaa gcgtccttct
    21781 accatttttt caacgatatt cgctggtttg ccttcgttca atgcttgttc tgtaagaaca
    21841 gttttttcat gttctaattc agcttctgga atttgtgatt cgtttacata acgaggattg
    21901 atagctgcta cgtgcatagc tacgtctctt gcaactgttt cgtcagttgt tccatctaga
    21961 acagtcaata cggcaatacg tccgcccata tgcaagtatc caccaaatgc agcattgtcg
    22021 tctttttcta caacttcaaa gcgacggaag ctgatttttt ctccgataac ttgagttgct
    22081 tcgatcaagt cagattcaat tgtaccttta tctgttttga ttttcattgc agcttccatg
    22141 tctgctggtt tgttttcagc aacaagttct gcaatttctt ttactaaatc ttggaacatt
    22201 tcgtttttag aaacaaagtc tgtttctgag tttacttcaa cgattgctgc agtgttacct
    22261 ttcacagcaa ctgaagccaa tccttcagct gcaatgcggt catttttctt cgcagccttt
    22321 gccattcctt tttcacgtaa aagatcaact gctttttcca tgtcgccttc tacttcaact
    22381 aatgcttttt tcgcatccat cattcctacg ccagtcattt cgcgtagttc ttttaccatt
    22441 ttagctgtaa cgtctgccat gtttaactcc tcctgtgtgt ttttcttttt aaaaaaagct
    22501 gcttcaaagg agagtgaggc ttgtcgccca gcctttgaaa cagctccatc attcaaaatt
    22561 attctgctga agaattgtcg ccttcaacaa catctacgat ttcttcgatt gatgttgctg
    22621 tgttttcttc tgtgaaatct tcttcaacta cttgatcttc accttggttt ccttcgatga
    22681 aagcatcagc catttttgaa gtaatcaatt taacggcacg aattgcatcg tcgtttgaag
    22741 ggattactac gtcgatttca tctggatcgc agtttgtatc aaccatagct acgattggga
    22801 tatttaattt gtgtgcttct tgaacagcaa tacgttcttt acgtgggtca acgatgtaca
    22861 ttacatctgg gattcttggc atatcagcga taccgcctaa gaatttttca agacgttcac
    22921 gttctttgtt caaaccagca acttcttttt taggtagaac ttcaaaagtt ccatcttctt
    22981 ccattgcatt gatttgtttc aaacggctga tacgtttttg gatagtatcc cagtttgtca
    23041 atgttccgcc taaccaacga tggttaacga agtattgtcc tgcacgagtt gcttcttctt
    23101 tgattgcttc ttgtgcttgt ttttttgtac ctacgaataa tgctacgccg ccttcttcag
    23161 caacgctctt catgtaatca taagctgcat ctactaattt aactgttttt tgcaagtcaa
    23221 tgatgtagat tccgtttctt tctgtgaaga tatatttctt catttttgga ttccagcgac
    23281 gagtttggtg accaaagtgt acgccggctt ctagtaattg tttcatagaa attactgcca
    23341 tgtttgtttc ctccgatttg gttttatttt tcctcttctt atcttctacc ttgccggcaa
    23401 actttttcaa gcacctaccg acaatccaat aagaatgtgg atttgctgat gcataaagca
    23461 ccctcagcta ttatacagac aaaagatccg tatcgcaaga gcaaatatac ttttctgctc
    23521 aacattcaat agtttacctg aaagataaaa agaattcaag aaaaacagta gatttctctt
    23581 tgtttcttta ttatcctttt tccataaaat aattttaggt ataaaagacg aatattattg
    23641 ggcaatcctt cttttttttg ttatgataca tgtgaaatct ttcgtaaagg agaaagaaaa
    23701 tgcgcaaagc tcaaagacat ttgctgatta aacaagtcat tgaagaattc ccgatccgta
    23761 cgcaagaaga actattaaac aaacttgggc attatggcgt taccgccacg caggcaacga
    23821 tttctcgaga tatccgtgat ctaaaaatcg tgaaggcacc tgatgaaaat ggcgtttccc
    23881 gcttcgtatt gtttcgcgaa aaaggaactc ctgagactag gactgaggaa gaggatcggc
    23941 tggttcaaat gattgaagac attgtattga aagtcgaacg agtccacttt ttgacgatcg
    24001 tcaatacctt gccagacaat gctcatttat ttgcatctgt tttagatgag atcaaacctc
    24061 cctctattgt cagtacaatt gctggattcg atacgatcat ggtcatctcg gaaaatgagg
    24121 aggacgcaaa acgagtagaa gaatttcttc accatccaac tgaagtatca cttttttaat
    24181 cagagcacgt attcctaata tggaatgcgt gtttttttat tttcaatatt ttccttattg
    24241 aataaacctt tacactcttt acaaaaatac atcatttttt attcaaattt ttcaacacct
    24301 tgattgaatc acaataatca tcatttatat tggatgttaa caagagcagc ttcttgctct
    24361 ttgtgtattt caaaaaagaa atgaaaggaa atcatatgta taaattatta acttctggac
    24421 cattgacgac ttctgaaaca gtgaaaaatg ctatgctgat cgatcattgt acttgggatc
    24481 aagaatacaa agaaattaca caatggataa gaaaaaaatt attggatctt gctcaagtat
    24541 cggaaggaat atacacaacg gtcttaatgc aaggtagcag ctccttcggg gtagaatcgg
    24601 tattaagttc tgtgatcagg ccagaagata ctgtactgat ttgttcaaac ggcgcatata
    24661 gacaacgaat gatcaacatg tgcgaatgtc tgaaactgaa ctataccgtt tatgaggtat
    24721 cggaacatca aatcctccaa gctcatgtga ttacacagct gattgaagag aatccgtcta
    24781 tctccgcact agcaatggtc catagcgaga ctacttccgg tattttgaat aatttggaag
    24841 agattgctgc tgtcacacaa gaaagagatc ttttgtttat agtggacgcg atgtcaagct
    24901 ttggtgggat accgatttgt gtagccgaac tagggattga ttttttgatt tccagctcaa
    24961 acaaatgtat tcaaggtgtt ccaggctttt cttttgtact tgctaataaa gcggaactgg
    25021 aaaaacgaaa aaatgttagc cgaagtttgt cacttgatct atatgaccag taccgcgtga
    25081 tggaaaacga gaatggcaaa tggcgtttca cttcccctac ccatacggtt ttggcttttc
    25141 aacaagcgct gaaggaacta gaggcagaag gaggaatcga aactcgatat tcacgttatc
    25201 tcgccaataa tcatgtgcta cgacaaaaaa tgacagagat ggggttccag cctttcattc
    25261 aagaatatca ggggccattc atcacctctt ttctttaccc taaggactgg cgatttgatt
    25321 ttaatcattt ttatcagtat ttaaagcaaa atggatttgt gatctatccc gggaaaatca
    25381 gcgatcatga atgttttcgt atcggaaata ttggcgagat ctatccggaa gatattttgg
    25441 aactgacagc aattatcaaa gactataagg agaacgttaa tgattaaaac tgtaattttt
    25501 gattgggcag gaacaactgt ggactttggc tgtatggctc ctgtccacgc ttttagaaat
    25561 gcttttctag aaaaaggaat ccaactgact gacaaagaaa tccgctaacc gatgggaaaa
    25621 ttaaaatggg atcatatcca acagcttctt tccctccctt ctgtcaaaaa acaatggata
    25681 gctatttatg gacaactacc tcaggaaaaa gaggtggagg aattgtatca acaatttgaa
    25741 cattatctgt ttaaagattt ggtcaagcat tctaccttga aacccgacac attggaaacg
    25801 atcgaacggt tgagaaacgc tgggatcaat attggttcca cgaatggatt taatgctcct
    25861 atgatgacaa tcgtagcaga aaccgcaaaa aaagaaaggt attcaccaga cttcatggca
    25921 acttttgaag acgtcgaagg gtatggtcga ccgtttcctt atatgatcca taaaaacatg
    25981 cagtacttca aaaacaagtc ggttgatgaa gtaatcaaag tcggagatac ggtctcagat
    26041 atccaggaag ggaaaaatgc cggagtgttg acagtaggtg taattgaagg tagttcgcta
    26101 atggggattt cttatgatga gtaccaaaaa ttagagatgg ggaaaaagat cgtttaaaac
    26161 agtctgttgc tcttagattc caacaagccg gcgctgatat ttgtgtaaac aatttaaaag
    26221 agttaacaga atacattttg tacgctgaca tgaatccaga atgactttta tacaaaataa
    26281 gaggttgtga aaaagctgtc ctgtatcaag taataaaaac agccaagcaa aaatagctcc
    26341 tcatattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa caccgtttat
    26401 tcgaaaaaaa aaagggagct gtgacacgac ttttgtcaca gtccccttat ttgcaaacaa
    26461 acagtgttta agagacaacc tctccactaa acggtgttca ttcagctgac tctcggtatt
    26521 tgctcaaaaa acgataaaat ttgaaaagct attttctctt ttgtttctct aatactcgga
    26581 tcagaacgct gatttcacat tctctttttc ttacatctta tctggtgcat gaagtcctag
    26641 caaacgaagg tcttctttca ataatacagt cactgcataa actagagcta agcgtgcttc
    26701 tttttgttca tcatcagcta aaatcttcgt atgagcatag tatttgttga atgcttgtgc
    26761 taatttgatt gcatgtttcg caatcactga cggttcgtat ttttccccag cagacaagac
    26821 cgtttcaggg tatttttgaa ctaatttaac cacttcccag ctggtatcgt cattcaatgc
    26881 atagtctgct gtttctgaag ggacaaatcc tgctttttcc aacaggctga ctgcacgagc
    26941 atgtgtatat tgcacataag gtccagtttc tccttcaaat cgaacaactt cttccaggtt
    27001 aaagtcaaat gtattcagtc gatcgttttt caaatcgtgg aaaatgactg ccccaacccc
    27061 aacttgttta gctacagcat ctttgttttc caaatcaggg tttttctcgc tgatttgttc
    27121 tttagcagat tggattgctt catttaatac ttcttctaat aagacgatct ttcctttacg
    27181 agttgataat tttttaccac cttgcgtgat caaaccaaat ggaatatggt gcatgtcgtc
    27241 agaccagtca aagcccattt ccttcaagac agctttcaac tgtttaaaat gatagctttg
    27301 ttcattccct actacatata gagattgttt gaagtcgtaa gtacgtttac ggtacaatgc
    27361 agcagctaag tcacgtgtaa tgtatagtgt cgcaccgtct gacttcttaa tcaacgctgg
    27421 attcaggtca taagcagata ggtcaacgat ctctgcacct ttatcctcgt tcagcaaatg
    27481 tttttcttct aaaagtttga cgatttcatc catcttgtca ttgtagaaag cttcaccgtt
    27541 caacgaatcg aaacgtactt ccagcagatc atagatttta ttgaattctt tcatcgattc
    27601 atcacggaac cattgccata attgaatagc ctctttatcg ccttcttcca gacgtttgaa
    27661 ccaagcacga gcttcttcat ttaattctgg ttctgtttca gctacttcat ggaattggac
    27721 gtataaacga agcaattcat tgattggttc tgctttaaca gcttcttctg taccccattt
    27781 tttgtaagcg acgatcagtt ttccaaactg tgttccccag tcacctaaat ggttgatgcg
    27841 gattggctga taaccgattt tttccataat gaaaccgatc gaattaccga taactgtcga
    27901 acgcaaatgt cccattgaga ttggtttggc aatattagga gaagacatgt cgattggtac
    27961 tgttccttga ttcccgatgt tgctatcccc ataatgttct ttttctttca ctactgtttg
    28021 caaaactttt ttgctgataa gttctttatt catgaaaaag ttcaagtaag gtccgacaac
    28081 ttcgattttt tcaaagttgg cagaatcgat tttttctgct aaatctgcag cgatttgctg
    28141 tggcgctttt cggtaaactt ttgctaatga aaaggctgga aatgcaacat ctccgtgttc
    28201 agctgatttt ggattttcta gtaattgctc gacttgttcc agtgttaaat catctttgac
    28261 agcgtcatag acagcttttg cgacaagatc tttattattc atctttattc ctcctaaagt
    28321 gttcccttga ttgttaaaca aaaaaaatct ctagcgacgg catacttagt atgccatcac
    28381 tagagacgag atttcccgcg gtaccactcc aattgtccta aaaaaggacc agctccatct
    28441 gatatcggta gacgaccgtc tgtttaaaac agaattctcc aagtgcgctt cgttgtatct
    28501 tcttcattcg gcttccacca cttccgaatt cgctagccaa gaatgataca agtactctct
    28561 tgttcaacaa atcttagtct tattaaactt tcttgaatta tatcagaaaa aaaaacgaaa
    28621 ggctagtcgt ttcataaaaa aacaatccag atggcctaaa ggagaagaaa taccacctgg
    28681 atagctataa atcatttcgt aaatacgaaa gacttaacaa attaatcagc tacgataatc
    28741 gttccttctt cagaagctaa aagattctcg atattttcta aagaagtgat gattgcctta
    28801 gcgtttggtt ttgcttcaac aaatgcaata gctgcttcta ctttcggaag catgcttcct
    28861 ggagcgaatt gcttttcatc aatgtattgt ttcatttctg aaacagtaac agtttctaat
    28921 ttcttttgat ctggtttttg gtaattgaca tacacattgt ctactcctgt caatacgatc
    28981 agcaaatccg catcgatgat ttcggctaat ttttctgaag caaaatcttt atcgattacg
    29041 gcttctcgtc cttctaatcc agtagctgtt tctacaacag gaatcccacc gccaccaaca
    29101 gagactgtga taactccttg atcgaccagc gtttcgatga cacgtgcttc tttaatcgag
    29161 atgggtttag gggaagcgac tacttttctc catccacgtc cagcatcttc tttgaatgtc
    29221 acagtggagt cagcattcat ttgttctttg gcttcttctt ccgtgtagaa tggaccgact
    29281 ggtttacttg gatttttgaa tgaaggatca ttttcatcca caataacttg agtgactaaa
    29341 gaaaccacat ctttatcgat ccctttttcc ttcagtactt cgcccatggc gttttgtaac
    29401 cagtaaccga tagatccttc tgtcattgca acacatgtat ctaaaggcat tgccggtgtt
    29461 ttctcagaat cagcagcttg ctgctgaatc aataggttac cgacttgcgg accatttccg
    29521 tgggagatga tcaattcatc tccttgttcg ataaatttca ctaaatactt tgctgtttcc
    29581 attaacgctt cttgttgggc ttttgcactt gcatccgtag acaagatggc attgccccct
    29641 aaagcgacaa ctacttttcg tttggccatt tcattcgtcc tttcttcagt tctaccgaat
    29701 tttctagata acaaaacgag ccagcgtttt gtgattttcc ctcaatgctg actcgttttt
    29761 tcgtgagatg aatgtggtta tgcttaaacg cgagggataa acaagttacc taatgttgct
    29821 gccatgatcg ctttgattga gtgcatacga ttttctgctt ggtcaaattg acgagcatat
    29881 ttgctgcgga agacttcatc tgttacttcc atttcagtga tgccaaagcg ttctttcatt
    29941 tgttcaccgt aaacagtgtt tgtatcatgg aaagctggca agcagtgcaa gaagatcaaa
    30001 cgatctgtgt tgtgtgtttt ttctaccatt tccatattga tttggtaagg tttcaacaat
    30061 ttgatacgtt cttcgaattt atcttcttca cccattgata cccatacatc agaataaagg
    30121 acgtctgctc cgtctacacc tttatcaaca tcgtcggtaa tcatcaattg tgcaccggat
    30181 ttttcagcaa agccttctgc cattttgacg atttcttctt caggttgtaa ttcttttggt
    30241 gcaacgatac gcatattcgc tcctaaaatt gcacctgtga ctaataaaga gttagccata
    30301 ttgtttcgac catctccgca gtaagcaaca gtgatacctt ctactgttcc aaagttttct
    30361 tggatagtta aaaagtcagc gatcatttgt gttggatgcc attcatcagt caagccattc
    30421 caaactggaa caccagagaa ttctgctagt tcctctacca ttttttgact gaatccacgg
    30481 aattcgattc cgtcaaacat acgtcctagt actttagctg tatcttctgt ggattctttt
    30541 ttacctaatt ggatatcatt tgcacctaga tattcaggat gtgcacctag atcgatcgct
    30601 gcagtagtaa atgcagaacg agtacgtgta gatgtttttt caaataaaag cgcaatattt
    30661 tttccttcta gatagtgatg tgggatacca cgttttttca agtctttcaa gtgttctgaa
    30721 aaatcgatca aatattgtaa ttcttctttt gtaaagtctt tttctgctaa taagcttctt
    30781 ccttggaata ctgattcttt catattaaac attctccttt agattgtttt tatttaagat
    30841 taaagaggaa atcccgacgg cagctgacag taagactgcc gtcaggaaac aaattacttc
    30901 aagtcttcac ggacaagtgg ttggctcatg cagcgtggac caccacgacc tcgtgacaat
    30961 tcacttgaat tgatttctaa cactttgatg ccatagctac gaagcaattc gttcgataca
    31021 taatttcggt tataagtgac tacaacacct ggagcgattg ccaatgtgtt tgatccatca
    31081 ttccattgtt ctcgaggtgc aacgatctca tctccattac cagttgggat cagtacaaga
    31141 tcatctaatc caagagcagc tttcatcgtt tcgtgtaagt tatctgaatg agtaatcttg
    31201 atatcatcac catctggttc gattgtaaag acatccatct taccgtcttt actttgaatt
    31261 gctggatgga tagtgaattt atcgtgatct accattgtaa atacggtatc caaatgcatc
    31321 attgcacggt tgttcggaat tttgattgcc aacacttttt caaatcctga attttttgcg
    31381 aataggtggc gtgctaattt ttctaaagct ttcgcattag ttcgttgaga aatcccaaca
    31441 gctactactt tatcgcttaa gatcaattcg tctccgcctt cgatatgatc tggattttca
    31501 cgatccaacc atacttcgat tcctttattt gcaaatcttg gatgatgttt caaaatatat
    31561 tctgtaaaca tcgattcacg acgacgtgct tcaaaagtca tcttattgac tgtcatccca
    31621 tttcccattg atgcggaagg gtcgcgtgta aagtacaagt ttggcattgg gtccatgtaa
    31681 aatggatagt catcgtctgc tgacagatca tatagactgc tagaacgtac ttcgatatct
    31741 tttgtacgaa ccccagccat gattttatct accatttctt gcgtttccat tgatagaagg
    31801 aactcatgaa gaccctctct tacagcattc gatgcaatat gagattcatc caacatttta
    31861 ttcaagaatt gttctttgac attgcctgcg tcaatcgctt ctgccgctaa tttttccaag
    31921 taaagagtct cgacgccttc attttgcaat gtcttcgcaa agttgtcatg ttcttcttga
    31981 gcaatcggaa gatatggaat atcatcgaac aacagacgat ccataatatc tggtgtcaaa
    32041 ttttccactt cttgtccagg ccgtttcagt aaaactgtct ttaatttccc tatttcagag
    32101 aaaacgtgaa taggtttatc catgttgtgt tgcctccttc tttttgatta catgtatagg
    32161 atatcctcct tttgtaatca ctttcataat tttgtctcat tcaaaatgag acattcctca
//
LOCUS       DADVXK010000021        31864 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.021, whole genome shotgun sequence.
ACCESSION   DADVXK010000021 DADVXK010000000
VERSION     DADVXK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.021"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            1089..1403
                     /locus_tag="KB909_000913"
     CDS             1089..1403
                     /locus_tag="KB909_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836968.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(1456..2229)
                     /locus_tag="KB909_000914"
     CDS             complement(1456..2229)
                     /locus_tag="KB909_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836969.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            2334..2579
                     /locus_tag="KB909_000915"
     CDS             2334..2579
                     /locus_tag="KB909_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6836970.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            2735..3586
                     /locus_tag="KB909_000916"
     CDS             2735..3586
                     /locus_tag="KB909_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBB6836971.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            3619..4293
                     /locus_tag="KB909_000917"
                     /pseudo
     CDS             3619..4293
                     /locus_tag="KB909_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            4550..4738
                     /locus_tag="KB909_000918"
                     /pseudo
     CDS             4550..4738
                     /locus_tag="KB909_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            4784..5749
                     /locus_tag="KB909_000919"
     CDS             4784..5749
                     /locus_tag="KB909_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836972.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            5771..5983
                     /locus_tag="KB909_000920"
     CDS             5771..5983
                     /locus_tag="KB909_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6836973.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            6058..6534
                     /locus_tag="KB909_000921"
     CDS             6058..6534
                     /locus_tag="KB909_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBB6836974.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            6531..8339
                     /locus_tag="KB909_000922"
     CDS             6531..8339
                     /locus_tag="KB909_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6836975.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            8416..8631
                     /locus_tag="KB909_000923"
     CDS             8416..8631
                     /locus_tag="KB909_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBB6836976.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            8723..9586
                     /locus_tag="KB909_000924"
     CDS             8723..9586
                     /locus_tag="KB909_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836977.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            9623..10159
                     /locus_tag="KB909_000925"
     CDS             9623..10159
                     /locus_tag="KB909_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBB6836978.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            10173..10595
                     /locus_tag="KB909_000926"
     CDS             10173..10595
                     /locus_tag="KB909_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6836979.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            10525..12924
                     /locus_tag="KB909_000927"
     CDS             10525..12924
                     /locus_tag="KB909_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6836980.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            12956..14947
                     /locus_tag="KB909_000928"
     CDS             12956..14947
                     /locus_tag="KB909_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6836981.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            14970..15221
                     /locus_tag="KB909_000929"
     CDS             14970..15221
                     /locus_tag="KB909_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBB6836982.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            15211..16440
                     /locus_tag="KB909_000930"
     CDS             15211..16440
                     /locus_tag="KB909_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBB6836983.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            16437..18518
                     /locus_tag="KB909_000931"
     CDS             16437..18518
                     /locus_tag="KB909_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBB6836984.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            18667..22587
                     /locus_tag="KB909_000932"
     CDS             18667..22587
                     /locus_tag="KB909_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBB6836985.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            22588..23532
                     /locus_tag="KB909_000933"
     CDS             22588..23532
                     /locus_tag="KB909_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836986.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            23536..23739
                     /locus_tag="KB909_000934"
     CDS             23536..23739
                     /locus_tag="KB909_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBB6836987.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(24039..24275)
                     /locus_tag="KB909_000935"
     CDS             complement(24039..24275)
                     /locus_tag="KB909_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836988.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(24458..24844)
                     /locus_tag="KB909_000936"
     CDS             complement(24458..24844)
                     /locus_tag="KB909_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBB6836989.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(24826..26154)
                     /locus_tag="KB909_000937"
     CDS             complement(24826..26154)
                     /locus_tag="KB909_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6836990.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(26115..26444)
                     /gene="mobC"
                     /locus_tag="KB909_000938"
     CDS             complement(26115..26444)
                     /gene="mobC"
                     /locus_tag="KB909_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBB6836991.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(26702..27072)
                     /locus_tag="KB909_000939"
                     /pseudo
     CDS             complement(26702..27072)
                     /locus_tag="KB909_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            27217..27402
                     /locus_tag="KB909_000940"
     CDS             27217..27402
                     /locus_tag="KB909_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6836992.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            27560..27727
                     /locus_tag="KB909_000941"
     CDS             27560..27727
                     /locus_tag="KB909_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6836993.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            28345..29004
                     /gene="vanR"
                     /locus_tag="KB909_000942"
     CDS             28345..29004
                     /gene="vanR"
                     /locus_tag="KB909_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBB6836994.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            29007..30368
                     /gene="vanS"
                     /locus_tag="KB909_000943"
     CDS             29007..30368
                     /gene="vanS"
                     /locus_tag="KB909_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6836995.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(30459..31760)
                     /locus_tag="KB909_000944"
     CDS             complement(30459..31760)
                     /locus_tag="KB909_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6836996.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         8491 a         7788 c         8181 g         7404 t
ORIGIN      
        1 cgtacgatta ttaaaaataa taaattttca ctagaagaaa atggaaataa aatcaaataa
       61 ttaggaagaa aaaacaaagc aattagaaaa gcctgcaagc aaatttgagt aatcgagatc
      121 caattttttt aaggaagttt aacaaaaata tgtaattcta ttatcactat taaagagaaa
      181 gttggagcgg aatataaaga aaagagaaaa gtaattaaac gcaaaaaaat gtagaactta
      241 aaaaatataa agaggaacaa ccgttaaaat taggaatgat gttgtgtaaa cattataatt
      301 gctatgatat aaatgaagtg ttaaagaaag caaatttaaa ccaattttgt gaacagaaaa
      361 gccttagtca ctatgaccaa aactacggac gaaactatga ccaaaagtag gtactaaatt
      421 atgaccgaaa ataggtccaa aatggatttt tttatgatat caaaaattat gaaatgattt
      481 tgaaagaaaa ccagttggca cagccaactt agccaccttc ctgtaggaag gtgctatcag
      541 ttttccctta tgctcttttc tttctttttt gtttcatatg tcaaatgcca ttttgaaatg
      601 taccatctta agaaatttat ccttaaaaac aattgcgtta ttggataaaa agatgctaca
      661 ttatcttaaa aaaggaatca aatatgatga atttagtggc tagcatatcg tgtgattaag
      721 atactttata gtgtaagttg aaggagaaaa aatatttaaa atatacttcc catttcagtg
      781 ggaagtaaaa ttaatcttgt tgtttctact agtaatgtat ctttttggaa actatgtaac
      841 gatgtaaaca agattttttt cagaagaaaa aacgataaaa gttgtgataa acgatttaaa
      901 aaataggaga aaatatatca agcgcatggt atgaaacgca catttaaaaa gattcgacta
      961 actaaaaaaa taagtttaca aagcattgtt gtgtattaca agtgatctat acactgaaaa
     1021 atgatagaga aaatctgata cgtccgcaac aatggacaat tgaaaatgaa agtgaggaaa
     1081 ttggaagaat ggctgatgaa aataaagttg ttccgcttga aacactagtg ataaataagg
     1141 aagagtttga gcaacttttt cttgattttt ttgttcaata tgacaggatt tatgatttta
     1201 gttcgtcact agatttattt gaattagagg cagaaataat agaaaacagt cgagaggaga
     1261 atggtaaaat catcatttca gtagaaaaat tcaatgaatt attctcagaa acatttgaaa
     1321 tagatacaga ttattatcaa ccacaagaag ttttccaatc atttagaaat cagattattc
     1381 gctcaggtaa gaccgtaaac tgaaaaacaa taaaagaaac gttgaaagaa taattattcc
     1441 ttcaacgttt cttttttaga atgttttaat gaccaaagca gtttcattgt caggcttagg
     1501 taattcatga aatcccgtat ttatagtgct caattgatca actaaccatg ttttactttt
     1561 tgaattgtag ataaatctaa aattaatatc gttattatcg tgttgaaggg gcgtctccaa
     1621 ataatctgct gtatattcat agtcaacgta acctgctaat acaaaagaga gtatcccttt
     1681 atttaatgtt agatttaatg gataatcata cgactttatt tttttcaact tcatattgta
     1741 catatcttca gccataaaag ttgagttcgt gatttcatct tgggtctcat taaaaaagtt
     1801 atccgaataa tcgcttattt ttgaaaagtc tttattggca ccagcctcaa aaaattgttc
     1861 aactttttca gtataaagtt gtgctaacgc tcctttttca atattaactt taatattttc
     1921 atgtctatca atttgtgtgc tgttcagtaa gggaagatca gcttttagtt ttatatcgtc
     1981 ttgatttctt tcaatttcaa ttggcaaaat cttttcagta gattcagttt ctgataaagg
     2041 aacatctagt tttttatcat gataataagc ttcaaatcca tctggaaccg gaaaaaaatg
     2101 tattgggtaa ttcttttctg aggttgttgt actagtttcc gtacttgtag aacttgtgtc
     2161 agaagtggta cacccgctta tagttccgat gagtaaagcg caagttagaa tgattgcaaa
     2221 tttcttcaaa aaaattcctc cttaaaattg aatatggact aatactagtc ccattgtagc
     2281 ataccgaatc tttaagatta ataagaaaaa ggactaattt tagtccaaaa ggtgtgctat
     2341 tcttgaaaga ggaaaaaatt attgataaag aaaatgtaat cggtagcaat attagacgag
     2401 tccgattaga aaaaggaatt ggtcaaaccg agctgattag agacctacag cttcgtaaaa
     2461 ttgctataac tagggaaacg ttggttaaga ttgaaggtgg ccgccaacac attaagttgg
     2521 atcaattgaa agccatcaaa gatattctac aggtgtctta tgaagatttg cttcaatgac
     2581 tacttgtagt catttcgttt gaaattatta tgttacaccc ttatgtgtca cgaagaaata
     2641 ctggtataat aatgaatggg atatgtaacg atagggtata ctgttatgtt gcctaataaa
     2701 ttgtggatca aaatacaaga atggagggat atccttgtat aaggcatatg aattggattt
     2761 tacaaatgct gacttaaatg cattctcctc aagctcgcaa tcatatacac atgtagtaaa
     2821 tcaaatagat cacaaccaaa aatctattaa caagagaata gaaaatctat ttgaaagtga
     2881 aaatgattta gttgattatt attctaagga cagcaaaatt ctagatgcag acgaaattat
     2941 taaagattgg tttccaacta taaaagcaga tatttttata tctcactctc atgctgatga
     3001 aaaattagct atacgttttg catcatggct atttgaaaat tttggtctta ctgcatttat
     3061 tgattcttcg gtttggggat acagttctga tttattaaaa aaaatagacc aaaaatattg
     3121 ctataaggaa caaacaaaaa catatgatta tgataaaaga aatgtaacaa ctagtcatgt
     3181 tcatatgatg ctttctacag ctttaaataa tatgattgat agtacagaat gtctgttttt
     3241 tcttaataca cctaattcaa ttagtttgag caatgaaatc actaatgaac agaaatttac
     3301 gtattcgcca tggctatata gcgaactgac gacagcttca atagtggaaa aaaagaatcc
     3361 acgattggaa agtaatcctc aaatgagcac cgaggatgtt agaagcatta taaagcacta
     3421 ttcttcgcaa gaaaatctgc aaataaaata ttctttaaat ttaagtgaat taacttattt
     3481 acgaaaagct gatttgaaaa aatgggcttt agatgctgtg gaatgcacta aaggaagtaa
     3541 tacattagat attttatata aaaacaccat tttcactaat ctctaatcaa tttactgaat
     3601 cgaaaggaac cgggtagaat ggataagaaa gttttaataa agaggttctc tgaagctatt
     3661 gaaaaaggaa atgcagcaat atttgcaggt gcaggattat cgatgtcaca aggatatgta
     3721 agttggccgg aactacttaa tgatcctgca acagaaatcg ggttggattc taaaaaagaa
     3781 acagacttag ttactctggc tcaatattat aaaaatgaaa atggtggatc aagaggaatt
     3841 ttgaatcaga tacttatgga taattttggt gaagaattag aaatatctga aaatcatcga
     3901 atactagcaa gtttacctat tgaaacttat tggacaacta attatgatca tctaatagaa
     3961 aaatcaatcc gagaagctta taaaaaccct caggttaaga aaaattatac tcagttagca
     4021 acaactaatc caaatgtgga tacaattgtt tataaaatgc atggtgatat agatgatgtc
     4081 agttcgacag taataacaag agatgattat gaaaaatatg atgattcgta cgcgttattt
     4141 aaagaaactt taaaaggaga tttgttaaca aaaacttttc tctttttagg atttagtttt
     4201 acagacccta atttagaaag aattttatca gatataagat gggttttgag agaaaaccaa
     4261 agacctcatt attgtataat gagaaaaata ttatagaaaa aattttaggt tatcgctgaa
     4321 agccccggaa atacgggcat ttcgcaggat atgagaactc aatttactac caatttacta
     4381 ctttcggatt gagccgcata tatgctgaac catactgcta atacccgcca ccccaaatac
     4441 ggcacatcat aaattgaata cgacaccgta aacgcggcgt tcctctttcc cgtcatggga
     4501 gaacaggacg ccgctttttt atgcccaaat agagaaagga ggcgacgcca tgctatttac
     4561 ttccggccct gaccgggcgt ttgaacggct gatgcaggaa aagcccggtt tcgatcacta
     4621 cgacggcggc ggggcggacg cgccggagga ttgcggcacc tgccgatttt accgcccgga
     4681 ttggaaatat caattctgcc agtttgcaga gtgtccctat cagccgggca agctgaccga
     4741 ctatgcagcg gtcaaattca cagtgaaagg agcgaacaac gctatggcag ttttccgtgt
     4801 ggaaaagaac aaaggctata cggtgatgtc aaatcaccac ctgcggaata agaacctgac
     4861 cttaaaggcc aagggcctgc tgtcgcagat gttgtccttg ccggaggatt gggactatac
     4921 cctaaaagga ctgtcctata tcaaccggga aagcatcgac gcgatcagga cagcggtatg
     4981 ggagcttgaa aaagctggat atatccggcg tgagcagggc cgtgacgcaa aaggcaaaat
     5041 ggccgatatg gtctatacca tctacgaaca gccggtattg gaaaacccgg tattggaaaa
     5101 tccaacatcg gataacccgg tgttggaaaa tccgacatcg gataatccgg cgtcggaaaa
     5161 tccaacgcaa ttaaataaag aagtacaaag aactgactta tcaaaaaaag aaaaaataat
     5221 tacagatgga caaagtaccc attccattcc tatcccatcc ccgacccctg cccctatgga
     5281 gggcgaggca gcggctacgc cgccggaacg gaaaaggaca ggaaaggatg aggctgtacg
     5341 gatttatcgg gaaatcattt tggagaacat cgagtatgcc tatctcattc aggacaggag
     5401 cattgaccgt gaacagcttg acgaaatcgt agacctgatg ctggaaaccg tctgcaccgc
     5461 ccgaaagaca atccgtgtcg ccggggacga ctaccctgcc gagctggtga aatccaagta
     5521 catgaagctg accggcgaac atatccgctt tgtccttgac tgtctgcggg agaacacaac
     5581 gaaagtccgc aatatcaaac aatacctgcg ggctatgctg ttcaacgccc ccagcaccat
     5641 ttccaactac tacacggccc ttgtcgcgca cgacatggca cagcccgatt ggggaaagcc
     5701 taaatccggc ctgccggact attcctgcgg cgagggcgaa agcctgtaac gagaaaagga
     5761 ggacgaccct atgaagcagg gcgcattgat ttttgacgag cgaacagacc gttacgacat
     5821 ccgctttgat ctggccgact attacggcgg cctgcattgc ggggagtgtt tcgacgtgat
     5881 gatcggcggc aaatggaggc ccacccgcat tgaaatggcc gaaaactggt atcttgtcgg
     5941 catccgggcc gacgaccttt ccggcctgcg ggtgcggatt tgacctatat ctacctgcgg
     6001 cgtctggtgg ttccgcctta gacgccgctt ttgactttct gacaaggagg gatgcgattg
     6061 caggaagaag ttactcaaaa gaccattgcc ctgtccatga aaacgggcaa gctcacggct
     6121 caagtgctgc aagcggcgct gaaaaagtac ctgcaacacc gggccaaggg caaaaacacg
     6181 ctgcaccacg gccagcagag cctaaagcag cttaaaaagc atggggctga tctctccaac
     6241 attgagatca ccgaggccaa cattggagcg ttcaagccat gcgccaagaa atacggcgtg
     6301 gattttacct tacgaaaaga taagaccacc cagccgcccc actacgttgt gattttcaag
     6361 gccaaggatg cagataacct tgatctggcg tttcgggagt ttaccgccaa gacgctttcc
     6421 aaggagcagc ggccctctat ccgcaaggtt ttgtccgctg tgaagcaaaa ggcggcggcc
     6481 cagaccaagc agcgggccaa ggagaaaatc aaggaaaggg ggctggaact gtgaagcctg
     6541 acgtaaagaa attgctgatc ctgaacctcc cgtatctgat ttttgtgtac ctgtttgcga
     6601 aatgcgggga ggcgtaccgg ctggccgctg gtgctgacct gtcggggaag ctcctgcatt
     6661 ttgcggatgg ttttgcggcg gcttttgcca acccgctgcc aagcctgcac ctgtttgacc
     6721 tgtgtatcgg tatcgccggt gccgtgatcg tgcggctggt ggtgtactgc aagagcaaga
     6781 acgtgaagaa ataccgcaaa ggcatggagt atggcagcgc ccgctggggg acggccaaag
     6841 acatagcgcc ttacatcgac cccaagtttg aaaataatat cctgctcacc caaacggaac
     6901 ggcttaccat gaccggcagg cccaaagacc ccaagacagc gcggaataaa aacgtgctgg
     6961 tgatcggtgg cagcggttca gggaaaacga gatttttcgt gaaacccaac ctgatgcaat
     7021 gctttccgac cacggactat ccgacttcgt ttgtggtgac agatccgaaa ggcactttgg
     7081 ttctggaaac cggcaggatg ttccagcagg cgggctaccg cattaaaatc ctgaatacca
     7141 ttaacttttc caagtccatg aagtacaacc cctttgtcta catccattcg gaaaaggacg
     7201 tgctaaagct ggtaaatacc ctgatttcca acaccaaggg cgagggggaa aagtcagcgg
     7261 aggatttttg ggtgaagtcg gaacggttgt tttattcggc cctgatcggc tatatctggt
     7321 acgaggcccc agcggaggaa atgaacttct caacgctgct ggaaatgata aacgccagtg
     7381 aagcccgcga ggacgacccg gagtttcaaa gccccgtcga tctcatgttt gagcgtttgg
     7441 agcagaaaga ccccgaccat tttgcggtgc gccagtacaa gaaattcctg ctgtccgcag
     7501 gcaagacccg ttcttccatc ctgatttcat gcggtgccag acttgcgccc tttgacatcc
     7561 gggaggtacg cgagctgatg gaggacgacg aaatggagct ggacaccatc ggggacgaaa
     7621 agacggtgct gtatctcatt atgagcgata cggacacgac ctttaatttc attctggcta
     7681 tgctccaaag ccagctaatc aacctgcttt gtgaccgggc tgatgatgtg tacggcgggc
     7741 ggctgcctgt ccatgtacgc ctgattttgg atgaatttgc caacattggc caaataccca
     7801 atttcgataa actcattgcc accattcgaa gccgtgaaat atcggcctct attattttgc
     7861 agagccagtc gcagctaaaa gcgatttaca aggacgccgc cgagatcatt tcggataact
     7921 gcgatagtgt gcttttcctt agtgggcgcg gcaaaaatgc caaggagatt tccgatgcgc
     7981 tggggaaaga aacgattgac agtttcaaca ccagcgagaa ccggggaagc caaacgtccc
     8041 acggattgaa ctatcaaaaa ttaggaaagg agttgatgtc ccaagacgaa attgccgtga
     8101 tggacggcgg caagtgtatc ttgcagctac ggggtgtgcg cccgttttta tcggagaaat
     8161 tcgatattac caagcatccc cggtacaaat accttgccga cgccgacaag aagaatacct
     8221 ttgacgtgga cagatttttg actatcacgc gccggaaacg gcagcaagtg gtaacgcagg
     8281 atgaagtatt cgacctgtat gaaatcgacc tgtcggacga ggacgccgcc gctgaataaa
     8341 cagcggcttt tttcattcca acaacaaaat caaaaaatca ttatgagccg gaaaccggca
     8401 gaaagaggta aatttatggc attttttaat tccgcagtta ctactttgca gactatcgtg
     8461 atcggactgg gcggcgctct gtgcgtatgg ggcggcatca atctgttgga gggatacggg
     8521 caggacaatc cgggggcaaa atcgcagggt gtcaagcagc ttgtcgctgg cggcggcgtg
     8581 gccctgatcg gtgtcactct ggttcccctg ctgtccgggc tgctgggctg atcctggcct
     8641 ttgtccctgt ccaaaccctt aactaatcgc ctccgcgtcc tcccggccag accgggaggg
     8701 cgcgggaaag gaggtgctac ccgtgattag tgaaatcatt gaagaatgga taaaaggcat
     8761 cctcatggac ggtatcacgg gcaacctgtc cgggctgttc gatacggtaa atgccaaagt
     8821 cggagaaatc gccgccgacg tgggacgaac cccgcaggca tggaacagcg gtattttcaa
     8881 tatgctgcac agcctgtcgg aaaccgtgat cgtccccata gccggggcca tactcgccct
     8941 tgtcatgtgc tatgagctta tccagatgat aacggaaaag aacaatatgc acgactttga
     9001 cagctccatg ttcttccgct ggatattcaa atccgcgttt gcaatcctga tcgtaacgaa
     9061 cacatggaac atcgtcatgg gcgtattcga cgccacccaa agcgtcgtca atcaaagcgc
     9121 cggtgtgatt atcgggcaga catccattga ttttaacacc ctgataccag accttgaaag
     9181 ccaattggag gctatgagcg tgggcgctct tttggggctg tggttccaaa cccttgttgt
     9241 gggcctcacc atgaatatcc tttccatctg cattttcctt gtgacctatg gccgcatggt
     9301 ggaaatctat gttgtcacgt cgctggggcc tatccccctt gccacaatgg gcaacgcgga
     9361 atggcgcggc atgggccaag ggtatctgaa atccctgctg gcgctgggct tccaagcctt
     9421 tttaatcatg gttgtggtgg gtatctacgc ggtgctgata cagaatatcg gttccgcttc
     9481 cgacatatcc ggcgcaatct ggggctgtat gggctatacg gtgctgctgt gcttctgcct
     9541 gttcaagacc ggcagtatat caaaggccgt attcggggcg cattgatccc aaaatccaag
     9601 catacacagg aggaacttgt ttatttcaac gtacaacatc atttacgctg acccgccgtg
     9661 gcggtatgac tgcaaaaacg tacagggcgc agcggaaaat cactattcca ccatgagcat
     9721 tgacgagctg tgcgccctgc cggtggaacg gctggcgtcc aaagactgcc tgctgttttt
     9781 gtgggccaca ttccccatgc tgccggaagc tctgcggtta atcaaagcgt ggggcttttc
     9841 attcaagacc gtggcttttg tatggctgaa acagaaccgt aaaagcctta catggtttta
     9901 cgggctgggc cgctggacaa ggggaaacgc ggaaatctgc ctgctggcaa cacacggcaa
     9961 gccgaagcgt cgttctgcct ctgtccatca gtttattatc agcccgattg aacaacacag
    10021 caaaaagccg gatgtgaccc gtgaaaaaat cgtagagctg gcgggcgatt tgccccgcgt
    10081 ggagctgttt gccagacaga aaacccccgg ctgggacgtg tgggggaacg aggtggaatg
    10141 tgaccttatc ctgacgtgaa aggaggtgcc aaatggctta tgtaaccgtc cccaaggact
    10201 taacccatgt gaaaagcaag gttgtgtttg ggcttaccaa acggcaactg atctgttttt
    10261 ccggggcgct ggtgatcggc gtccccttat attttctcac ccgtgactat cttaccaaca
    10321 gcgcggcggc cctgctcatg gtatttgcca tgctgccggg ctttttgctt gccatgtacg
    10381 agcgtcacgg ccagcccctt gaagtggtga ttatgcagat catccagtgc tgcttcatcc
    10441 agccaaagga gcgtccctat cagaccgaca acacctacac cgcccttgtg cggcaatacc
    10501 agatggaaca ggaggtaaag gccattgtcc aaaaaggaaa tcccaagaga aaccgaaaaa
    10561 acaaagctga cccgcgccca gcgaaaagaa attgacgcgg taatccgtaa atataagggc
    10621 gacggcaggc cccacacggc gcagcagagc atcccctacg aggtcatgta cccggacggc
    10681 gtgtgccggg tatcgcccgg cgtcttttcc aagtgcattg agtttgcgga catcagctat
    10741 cagcttgccc agccggacac gcagacggct atctttgaaa aactgtgcga cctgtataac
    10801 tatgtggacg cctccattca tatccagttt tctttcctca atcggaaagt tgacccggtg
    10861 cagtacgcca agagctttga gatcgcgccg cagggggacg acttcgacga catccgggcc
    10921 gagtacaccg gcattctgca aaagcagctt gcaaacggca acaacggcat ggtaaagacc
    10981 aaatacctga cattcaccat cgaggccgaa agcgtgaaag cggcgcgagc cagattgaag
    11041 cgcatcggct ttgacctgtt aggctatttc aagagcatgg gggccgtagc ccatgtgatg
    11101 gacggctggg aacggctgaa cctgctgcat ggcgtgtacc acccggacgg cgagatattc
    11161 aattttgact ggaagtggct ggccccgtcc ggcctctcca ccaaggattt tattgccccg
    11221 tcctccctgt gcttcggcaa tgcaaagaca ttcggcatgg gcggcaaata cggcgcggta
    11281 agtttcctgc aaatcctgtc cccggagctg tcggacgata tgctggccga cttcctcaat
    11341 acggaaagcg gtgttttagt caatctccat gtgcaggcca ttgaacagac caaggcgatc
    11401 aagaccatca agcgcaaaat taccgacctt gacgctatga agattgcgga gcagaaaaag
    11461 gccgtccgca gcggttacga tatggacatt cttcccagcg accttgccac ctacggcgag
    11521 gacgccaaga agctgctgac aaagttgcag acccgcaatg aacggctgtt ccagttgacg
    11581 ttccttgtcc tcaacgtggc cgacaccaag caaaagctga ataacgacgt gttccaagcc
    11641 gcaggcgtgg cccaaaagca taactgtccc cttgtccggc tggactacca gcaggaacag
    11701 ggccttgcaa gcagcctgcc gctgggcgtc aatcagatca agatacagcg cagccttacg
    11761 acttccagcg tggccgtgtt cgtccccttt gtgacgcagg agctttttca gggcggcgcg
    11821 gccatgtatt acggcatcaa cgccaagtcc cgcaacatga ttatgctgga caggaagcag
    11881 gcccgttgcc ccaatgcctt gaagctcggc acccccggca gcggcaaatc catgagctgt
    11941 aaatccgaga tcgtcagtgt gttcttaacg acgcctgacg atatttttat ttcagacccg
    12001 gaggccgaat attaccccct tgtcaaacgg ctccacggac aggtaatccg gctgtcgcct
    12061 accagcaagg actttgtgaa cccgctggac atcaacctga attattcgga ggacgataac
    12121 ccgctggccc tgaaatccga ctttgtgctg tcgttctgtg agcttgtcat gggcggcaag
    12181 aacgggctgg aagccattga aaagaccgtg atagaccggg ctgtgcgcgt gatctaccgg
    12241 ccctatctgg cagacccccg cccggagaat atgccgatcc tgtccgacct ccacaaagcg
    12301 ttgttagatc agcatgtccc ggaggctgac cgggtggcgc aggcccttga cctgtatgtg
    12361 tccggctccc tgaacgtatt taaccaccgt accaacgtgg acatcggcaa ccggcttgtg
    12421 tcctttgaca ttaaggagct gggcaagcag ctcaaaaagc tggggatgct cattgtccaa
    12481 gaccagatat gggggcgcgt cacggccaac cgaagccaag gaaaggccac atggtatttt
    12541 gccgacgagt tccatttgct tttgaaagag gaacagacgg cggcctattc tgcggagatt
    12601 tggaagcggt ttaggaaatg gggcggcatt ccaacaggtg ccacccagaa cgtcaaagac
    12661 ctgctttcct ccccggaaat tgaaaatatc cttgaaaaca gcgacttcat tacgctgctc
    12721 aatcaggcgt ccggggatag aaaaatcctt gcggaacgct tgaatttgtc caccgaacag
    12781 cagaagtaca tcgacaattc cgaacccggc gagggccttt tgatctttga aaacgtggtg
    12841 ctgcccttta ccaaccccat cccgcacaac acccagcttt acaagattat gacgacccgc
    12901 ttaaacgagg tggcgggagt atgacccggc gacgccacaa aggaggtgaa ccaccatgaa
    12961 agagctgaaa gccaaggcga aagtgacgca ggccatgacc cgcgacgggc tgacgctgga
    13021 aaatcaggcc accggcgagg tggagaacat ttccagccgg gaggccgaac aggatttgtc
    13081 cgcgccgggg ccgggcggca ccgccgataa gctgctggaa cgggccgacg ccatccatga
    13141 cggccataag gccaagaaag ccgcgaagca ggccggggct gtggccgccg agggggacgc
    13201 tgccctgcac cggccatccg cccggctcca actgtcggag gaagaacggg ccgacccgga
    13261 tttacagccc tatatccgaa aatcggacaa acgggccgat aagctggata aggcccgcgc
    13321 cgccatcccc aagaagcgcg tcccggtcaa ggaaaccgtc tttgacgagg caagcggcaa
    13381 agcaaagacc gtcctgcact ttgacaaaca ggacaagggg cctccctccc tgaaacccaa
    13441 tccggcaggc cgtcctgttt ccgaggtttt tctattcggc cacgggaaaa tccatgaagt
    13501 cgagcatgaa aacgtgggtg tggagggcgg ccataagggg gaggaacttg ccgagcggca
    13561 ggccggaaaa gccatccgca gcaccatccg gcaccacagg ctgaaaccct actgggacgc
    13621 ggaaaaggcc gagcgcaggc tattgtctgc caacgcggag tatttctacc agaaatcttt
    13681 gcgggataac ccggagatcg cacaggcggc cagcaacccc atttcccggt tctggcagaa
    13741 acagcagatc aagcgccagt acgccaaggc cgcccggaca gcgggccaga ccgcaggcgc
    13801 ggcggcacag ggcgcggcca agacagccgg ggcctccacg aaagcggcca aggccgcagc
    13861 caaagaaagt gaacgggcgg cctcctttgt ggcccgccac tggaaagggg cgctggccgt
    13921 ccttgtgttg gggcttttga tgctgcttat catcggcggc ttacagtcct gcaccgccat
    13981 gttcggcagc gccggaagcg gcatcacggc gtcctcttac ttttccgagg atagcgatat
    14041 gttggccgcc gaggacgcct acgcggagct ggaagccgag ctgcaagact atctggacaa
    14101 ctacgaggcc acccatgact atgacgaata ccattttgac cttgacgaga tcagccatga
    14161 cccctatgtg ctgatttcca ttctgtcggc gctccatgac gggatattta ccatcgggga
    14221 ggtacagggt gatttgtcca tgctctttga caagcaatat atcctgacag aaaacgtcgt
    14281 ggtagaaacc cgttaccgca ccgaaaccga tacatggacg gacgcggagg gcaacaccca
    14341 tacagacacc taccaagtgc cgtatgacta ttacatctgc tacgtcacgc tggaaaactt
    14401 cgacctgtcc catgtgccag tctatatcat ggacgaggaa acgctaagtt tctattccct
    14461 gtatatgtcc acgctaggaa accggcctga tctgttttcc ggcagccagt accccaacgc
    14521 ctccaccctg acgccgccga cctactacga cgtacccccg gaggctttgg aggatgccac
    14581 ctttgccgcc atgctcaaag aggcggaaaa atatatcggt tatccctatg tgtggggcgg
    14641 cagctctccc agcaccagct ttgattgcag cggcttcatt tcgtgggtaa tcaatcatag
    14701 tggatggaac gtgggacggc tgggggcgca gggcctatat aacatctgca cccctgtttc
    14761 cagttcgcag gccaagcccg gcgaccttgt atttttcaag ggaacctacg acacccccgg
    14821 cgtgtcccac gtcggcctgt atgtgggcaa caatgtgatg ctgcattgcg ggaacccgat
    14881 ttcctacacg aaccttactt caaactactg gcaatcccat ttttacagtt acgggcgttt
    14941 accttaacgc cagaaaggag ctttcaatta tggcaaccaa acttgaccgc atcgaaaagg
    15001 acatccagaa aaccaagtct aagatcgcgg agtttcagaa acagcttcgg gagctggaaa
    15061 cgcagaaaac cgaacaggag aatttgcaga tcatccagct tgtgcgcggc atgaacatga
    15121 agccggagga atttgccgcg ttcttacgca gcggcgcaat gcaggccgcc cctgccgcaa
    15181 ccccttacca tgaacaggag gacaatgccc atgaagaata agaccagacg gatttcccgt
    15241 attctccccg cacttctggc cgtgatgctc tgcgtcacgg cctttcccgt taccgccctt
    15301 gcaggcggca atgacccggc accggccccg ctgccggagg ctacaaccga acccgctacg
    15361 ggcggtttgg agcctgaaac agacgaaacc ggcaccgcca cggacgggac agaaaccgag
    15421 gccgaaaaag ataccggccc tctgaccggc aaggacatca ccgacctgtt ttccgcgctg
    15481 ttcggttcca aggtgagcat tgccgccacg gacgacggca tccagatcac caccggcacc
    15541 gacaaaaaag aacctgaaca gaccggcacc gtcaccacca acggcggcag gctgaatgtc
    15601 cgcaccggcg cggggcttga caagaccgcg ttcacccagc ttcccaatgg gacgacggtt
    15661 gaggtagtcg gcacagacgg cgactggatt aaaattctct tgccggagcg catcggctat
    15721 gtccattccg actatatgac cgtcagcgaa aaggaagtag cggctaccgg cgagggcggt
    15781 ttttccctct ccattgaccc ggaggaaatt gcttctctgc tggaactgtt caatggcggc
    15841 ggggccagcg ccgccctgtc cccggacggg aacctgtcac tgattgacga catcggcagc
    15901 gccgcgaaaa atggcaagca gtttatcacc gtggaaacca aaaacggcaa tgtgttttat
    15961 ctgattattg accgggacga cgagggaaaa gaaactgtcc atttcttaaa tcaggtggat
    16021 gaagccgatc tgctgacgct gatggaggac ggggaaaccg tcacccccgc tgctgtctgc
    16081 tcctgtacca cgaaatgcaa ggccggggct gtgaacacga attgcccggt atgtaaaacc
    16141 aacctgaccg agtgcagcgg cccggagccg caggaacccc agccggagga acccgaagcc
    16201 ccggaggaag aacccaaggg cggcgcgggc ggcctgatcg tgttcctgct ggtggcgctg
    16261 gcgggcggcg gtgcggccct ttactatttc aagttcaaaa agcccaaggc tgaaaccacc
    16321 ggcagcgacg atttgggcga gtatgatttt ggggaggacg aggatttgga ggacgaggaa
    16381 cccgaaaccg agtttgaccc ggaagctgat tttgtgagtg aacaggagga cgaggaatga
    16441 catataaact tgtaatcgcg gaaaaaccca gcgtggcccg cagcattgcg ggcgtgatcg
    16501 gggccacgga gaaacacgac ggctatttgg aggggaacgg ctatctggtg agctggtgca
    16561 tcggacatct ggtgtccttt gccgacgccg gacgctatga cgagcgtttc aaaaaatggc
    16621 gctatgagga tttgcccatt ctcccggaaa catggcagta catcgtcccc gacgacaaga
    16681 aacagcagtt tgacgttctc tgttcgctga tgcagcgccc cgacgtgacc ggccttgtgt
    16741 gcgccaccga cgccgggcgc gagggggaat tgattttccg tttcgtctac cagatggcgg
    16801 gatgccaaaa gccctttgag cgcctttgga tttcctctat ggaggacagt gctattaagg
    16861 acggctttgc ccacctgaaa ccgggcggcg actatgatcc gctgtatcaa tcggccctgt
    16921 gccgggccaa ggccgactgg ctgatcggca ttaacgccac ccggcttttt tccgtcctgt
    16981 accacaagaa cctgactgtg ggccgcgtcc agacgccgac cttaaaaatg ctggtggaca
    17041 gggacgccaa gattaccgat ttcaagaaag agaaatatca catcgtccat atcacggcgg
    17101 gcggcgcgga cgcggtaagc agccgctttt ccgacgctgc cgaggcaaac accgtcaagg
    17161 cggcttgtgc aaaagcgcag gccgtttgcg tttccgtgac gcgggagaaa aagacggaac
    17221 agccgcccaa gctctatgac cttaccacct tgcagcggga ggctaaccgg cttttcggct
    17281 ataccgccaa gcagaccctt gactatgccc aggcactgta tctaaagaag ctgctgacct
    17341 atccgagaac ggatagtcaa tatcttaccg acgatatgct gcccgccgtg gaaagccttg
    17401 tgtccggcct gtgggagctg gtgccgtttg ccaagggcct gaacctttcc ccgcagtttg
    17461 accgcatcct gaacagcaaa aaggtgtccg accaccacgc cattatcccc accgctgaat
    17521 ttgtgaagca gggctttggc actctggccg agagtgaaaa aaagctgctg tccctgatct
    17581 gctgcaagct cttatgtgcc gtggccgggc cgcatatcta tgaggccgtc accgccacat
    17641 ttacctgtgc cgggcaggag tttaccgcca agggcaagac cgtcctttcc cccggctgga
    17701 aagagattga acgccggttc cgttcttcct taaagaccga cgccgacgag gacgccgagg
    17761 cggtgcggga gctgccggag ctttgcgagg gccagacctt tgcagacgtg gccgcctctg
    17821 tcaccgagca tttcaccacg ccgcccaagc cctacaccga agatacgctt ttgtccgcta
    17881 tggaacgggc cggggccgag gatatgccgg aggatgccga gcgcaaggga ttaggcacac
    17941 cggccacccg cgccgccatt ctggaaaagc tggtgcagat gggctttgtc cagagaaaag
    18001 gcaagcagct cattcccacc aaggacggca tcaatctggc tgtggtgctg ccggaggcgc
    18061 ttacttctcc ccagcttact gccgaatggg aaaaccggct gaccgagatc gccaaggggc
    18121 aggccgatcc tgacgaattt atggacggca tcgagacgca ggcgcgggag ctggtgcaga
    18181 cctattcctg tatcagtgag gaaaagcaga aattgtttca ggccgagcgt gttcctatcg
    18241 ggacgtgtcc ccgctgtggt gaggctgtct atgagggcaa gaaaaactac tactgcggaa
    18301 accgggcctg ccagttcgtc atgtggaaga atgaccgatt ttttgaggaa cgcaagaaag
    18361 cgttcacccc gaagatcgcc gctgcgctgc tcaaaaccgg caaagtcaag gtaaagggcc
    18421 tctattccgt aaagaccggc aaaacctacg acgggacggt gcttttggct gataccgggg
    18481 gcaagtacgt caactaccgc attgaacaca ggagctaaag gacagtaaca cagcaagcat
    18541 agggagtgtg gctacactcc cggtaaaatc ccccggccgc gtccctgccg ggccggggat
    18601 ttttgcttgt tggggaagtc cccaaccccc tattttttga aacagaacag agaaaggagt
    18661 gaccgcgtga acgaagtatt ttctatccaa gtccataacc ggcagttttt ggaacagggc
    18721 aaacaaggcg tctggctgga tttgcccacc acaaccgaaa cgctgcaagc cgccctgcgg
    18781 gatgttggca ttactgccga caatccgcag gattttttta tcaacgggta ttcctgcccg
    18841 gaggacagac accttgccat tccctatgac atggtgctgg ccgccgacgt ggacgagctg
    18901 aatttccttg ccgcccggct gggccagctt gacgccgccg agatcgcaga gctgaacgcc
    18961 gccctgcaaa atccccgtgg cggctttgag aatatcggcc agatcatcga ctacaccgaa
    19021 aatgtggatt actatgtgca tcttcccgac gttagggggg atggacagtt gggcgactac
    19081 tacctgaacc gttccggcat ggtggatatg ccggaggaat ggaaagccgg gattgatacg
    19141 gcgcagtttg gacgccacat tgcccagcag gaacaaggcg tttttaccca gtacggctat
    19201 ctggtgagaa gcggcgacga atggcagcgc gtccatgagg gccagccggt gccggaggaa
    19261 taccgggtga tgcactaccc ccagccggaa gctgaccggg aggaaccgca ggcccagcag
    19321 ccggaggcat ccgaaagccc cgacaaagcg ccgcccccgg ttatcccgat catgctggac
    19381 ggcatgaaca gcaaagaacg catgaaagtg attactgacc gtctggaaac cggcgtacag
    19441 gagctttttg aaagtagccg ctatatggct tacttatccg ctatgtccaa gatgcacgat
    19501 tacagtctga acaatacgct gctgatcgcc atgcagggcg gttcgattgt ggcgggctat
    19561 aacaggtggc aggatgaatt tgaccgccat gtgaagcggg gcgagaaagg cattaagata
    19621 ctggccccgg ccccgttcaa ggttaagcag cagatggaga aaaccgaccc ggccacccag
    19681 cagcccgtga tcggcgcgga cggcaagccc gtgaccgaag aacaggaagt gacggttccg
    19741 gcctttaagg tggtgacagt ctttgacatc agccagaccg agggcaagga ttttcccatg
    19801 ccctatatca gtgaacttac cggcgacgtg cagcagtatc aggatttctt tgccgcgctg
    19861 gaacggacat caccctatcc cataagcatt gagccgattt cagacggggc caagggccgc
    19921 tgcttctacg caaaacagcg cattgccatc aacgagggca tgagcgaatt gcagacccta
    19981 aagaccgcca tccatgagat tgcccatgcc aagctccacg ccattgaccg ggaggccccc
    20041 gccgaggaac aggcggcccg gccagaccgc agcacccgcg aggtacaggc cgaaagcgtg
    20101 gcctataccg tctgccagta ttacgggctg gacacgtcgg actattcttt tggctatgtg
    20161 gccgattgga gcagcggcag ggagttatcc gagctgaaag cctcccttga aaccatccgg
    20221 gccacggcca gcgaattgat aaccgagatc gacggccatt ttgcccagct tcagcaggag
    20281 cgcgaggccc ggcaggaaca ggaggccgtc acggttgacg ttaccccgga ggcagcggcc
    20341 ccggcgcagg ccgaggaaga acaggccccg gcccttgatc cggcagccga gccgcttgtg
    20401 actgtgctat ggagcgaaag cccccagcta aaggacggcc agcaaatgcc gttgcatgag
    20461 gccgacgcgc tgtttgcccg tctggatgca gcatatccgg cagaggcagg ctatgacaaa
    20521 accgcgttcc gcattgactg tatctttcag ggcgagccgg acagctacga ggggcggcag
    20581 gattttggag atagggacgg ttccctgatc gaacatatcc agagctacca ccaattttac
    20641 gcgcaggacg aaaactggaa aaagcatgta atcgctacaa ccggcataga gggctgggag
    20701 caggacaagg cccatcggga tatgctgtta ggcgagtttg tcccctatat gaagctgcat
    20761 tgcagccttg cccaaatgga acagacggcg cagggccgct tacagtccgg ggaaaccctg
    20821 acgccggagg aaacggccta tttgggggcg cttctctctt atgtgcagga gtgccgcccc
    20881 atgctcaatc agggccagta tcagttgccg gagccgccga aactggctga cttcgaccag
    20941 agcttgcagg actacaaagc acaggtacag gccgagatcg cgcaggaggc cgccgcagcc
    21001 ggtatgaccg tggaggaata cgcggcggct ggctatgaag caccccaaca ggacaccttt
    21061 tccatctacc agcttcgagg cggggaggaa acccgcgact atcggtttga gccatacgag
    21121 cgtttacagg ccgcagggct ggccgtggac agtgccaact atgaccttgt ttatacggca
    21181 ccgctggata aaagcacgtc tttggaggat atttaccgca cattcaacat cgaccacccg
    21241 gcagatttta ggggacacag cctttccgtt tccgacgtgg tggtgctgca ccagaatgga
    21301 caggacaccg cccactatgt agacagcttc ggctatatgg aagtgccgga gtttttgcgg
    21361 gaaaatcccc tgcgtaccgc cgaactgtct acggagcaga acgaaaacat gattgacggc
    21421 attatcaaca atacgccgcc cgaaccgcag ccggaggaac ccgaacagct atcttttgag
    21481 gatgtggcag ttgcttccgg ccagacacag gaggaacccc cggaggctgc gcccccgcaa
    21541 acggctgtcc gctattatcc catcaatgag ggagccgccc gccgcgccaa ggaagccatg
    21601 agcttttctg actaccggcc cggcagcgcc acggcggaat accggcacta tgtcgatcag
    21661 gccgtggaaa ttgcggagcg ccagaaaaag cgtgtggagc cagagtatca cgaaaagata
    21721 gacagcctcc ttgacaccta cgcccgcaag ctggccgaga acatgaataa gggctatgag
    21781 attaccgccc gcgtcccctc tgtcctgatt gccgggccgt ccaatttccc ggtacgggcg
    21841 aaagaaaagc agaacgccgc cagtgaccgc aacatggagg aatttcagta cattcagggc
    21901 ttgcttgaca aaatccgcag caccggcatg ggtggtatca gcgccgacga tccgcaggcc
    21961 gtttccaagc tggaaaagaa actggaaaag ctggaagcgt cgcaggagtt gatgaaggcc
    22021 gtcaatgcct actaccgcaa gcatgggacg ctggacggat gcccccatct gatcgaaaga
    22081 ggcattgaaa acctgaaagc ggatatggcg tcgggctggc actatgagaa aaaaccgttc
    22141 cagtcctggc agctctccaa caataacgcc gagatacgcc ggttaaaggg ccgcattgag
    22201 gaattgaccc gccaaaagga ggcggcctat gtgggatggg agtttgacgg cggcactgtg
    22261 gagatcaacc gggtggccaa ccgcctgcaa atcttctttg aggggaagcc ggatgctgct
    22321 gtacgcgacg agctgaaaag caacggtttc cgctggtcgc ccaaggccgg ggcatggcag
    22381 cggcagttaa acgacaccac aatccgcgtc gctgaccgta tcaagtgcat ccagcccctt
    22441 tccggcgaaa agcccagcgc cttacagctt gcggcccgca gggagaaaga aaagccctct
    22501 atccgggcgc agctcaacgc ggccaagacc gaacaggcca agcagccacc ggcgcgggaa
    22561 aaatcaaagg gattggaggt agagtaaatg cagaagtttg aaaatgtgga cgttctggcc
    22621 gcgctggaac agatcatgcg gcagaacacc gcgttttatc aaagtgactt tggcattgac
    22681 aaagacatta tcaggcggga tgccgccagc gatcaggccg cagacaagac cctgctctgg
    22741 atgtcccggc cctccgggac gtactgtttc cgggaacgtg atgttttcct gaaagacacc
    22801 cgacagtaca acacatggaa attttacggg gagcagaccc gtgacaagat actggcctac
    22861 gcggtggagc tgaccggcac acagggcggc actatccggg gcaatctcta tgagctggac
    22921 tatccgcagc atttccggca cgtcattgaa accgcccagc cggtgagtgt gaaccggctc
    22981 ttttatgagc atggcacccg tgacatcccg gagagccagc gttttgacgg aagccctgac
    23041 cgggtattgg gaaacttttt gtactatgag gcccagcccc atgacccggc tgtgctgcag
    23101 gaggcgctac ggacggagca gcacagccgg gggcgggccg tccccggcga tttcaaagtc
    23161 cacgtcaccg ctttgcatga cagccggatt gaaaccgagg cccggcgtat tgtggacagc
    23221 ctgaaagatc tgtccgcgcc taacagcccc aataaaacgc atttcatggt ggagatctcc
    23281 ccgcactttg cggcgattgc ttccaccaag gataatgacc ggctctttgc catgctgccc
    23341 tataaatccc tgtgttttac cgggatgaaa ggcaggcatg gcgtgtatgc cgtgattaac
    23401 cgggacgagc gccgggatgt gagtattcgc aggccccggc cctctatccg caagcagcta
    23461 tccgacagca aacaggccgc cagcccaaaa aaggcggcgg ccagaaccaa aaagaatgaa
    23521 ttggaggtat aaggaatgat gcactttacc gtggaggaag aaaacctgat ctgtatgtac
    23581 cacaatgcag accggcgcag aacgataaac aggctcaccg ccgtcatgcc ggttatggat
    23641 ggggatatgc gggcgcaggc ccagcagacc ctttccaagc tggaacgcat gacggatgcc
    23701 gactatgacg gccagaagtt ccacttcaca gacgaataac gaacagcaga cgccgggcgc
    23761 ggcggccatg tggtcgcttg cgtccggcgt cttttctttt tgcctattcc tacgcattta
    23821 gaacccggta ttgtcgggga taggatgaag tattcgcttg cccctgcaaa catgcgggag
    23881 aagccttgca gcgggcggtt ttcaatccct taaatgcgta ggttgcagct ataattagac
    23941 ccctgaaaca gatatagccg cgcagcgggt gtatctgttt caggggtgtg caggtgatag
    24001 ccgcaaagcg gcgtaagagg gtgcagccct cttgccgtct atctctgttc cagcgggaag
    24061 ctcggcaatg cttccagcag tttcagggaa atgcgctgcc gtatatcttc gtcaatgact
    24121 ttcttctttt tgccgtttgc ctgtctgatc tccaccgtgg aaagctcgtt gatgtagtca
    24181 gcataatggg ccaacacttt ttccgtggcc cacctctcac cggcaacggc ggctttgatc
    24241 gtttcatagt ccagcagctt ttcttgtccg tccatcctga tacccccgtc agactgattt
    24301 tttctatgat accatattcg gaagcatgga accagagaaa acggcgcttt tctgctggta
    24361 aattctacgc atttagaaca gcacttcggc ggggatagga taaaacaccc acataccccg
    24421 ctgaccatgc cggaaaagcc ttgaaatata agggctttta cagctctaag tgcgtaggtt
    24481 tccagtatct tttccgctgg cgctcggcct ctttgcggcg gcgcatccgt ttggagcagg
    24541 ccgcgcagta tttggcccgg ttagacttcg gcgtgaacgt ggccccgcac tcacagcagc
    24601 gtttcacttc gtcccggtct ttggtgatct cggcatacag ggccgcatcc agcgggagga
    24661 cagcggcctt aaaccagcgg cacagaagcg aataggaaat gctctgtacg caaatacatt
    24721 cttcgccgtc gtccagcaac aggcagttgc cgtcacaata gttgcagcac tcatgcgtca
    24781 gcttccgggc cttgcgatat tgagggtaat tcattcgtgg aatactcata gctcttgcgt
    24841 ccattccttt cccggcgtca tacgcaaaat gccgtccaca ttctgcttga tgatgccgta
    24901 ttcctgcatc tgctttttcg cttcgccgta cttctcatac agccgttcct tttcctcggc
    24961 caatcgcttg tactcggctt tcagggcgta cagatcgggg agctttttca caccctgtcc
    25021 ctttagggcc tttgccgcag cttcatacaa aatcaacgtg ctttcatgct cacgccggaa
    25081 ttttgcctta tccgctgcat tgcggtattc catagccacg ggccagagct gcttgtaggt
    25141 agaaatattc tttatcagca ccgccatatc cgcaagccgg tgttccatag ctttgagggt
    25201 agcggcggcc tcgtcgctgg cggcggtgat ctcggccact ttgctttcca aatccgggta
    25261 ggtgtctatc ccatgttcag tcaggaaatt caaagtcttt gcggcctgct tcaaattgtg
    25321 gagcttcgcc cacctctcat agcctgccga ctgctgggcc ttaatgttgt tttccagatc
    25381 aatccgcaaa gaaatcccct tgcgctcttt gggcgctctg gtgataacgc ggcctttgat
    25441 acgctctttg atggcttcct cggtgtaggc ttcccccaat gtcttgcagc gggtaaagcg
    25501 ttcctgtccg ggagcgcgga aagaaataaa ctttcccggc ttgatctcat agccctgcgc
    25561 ctgcatgagc cgcaggaaat catcaaaatc ttttgcctgc gggatagcgg cgtcaatggc
    25621 tgctttgagc ttcgctttcc agctcgtccc tttccgctgg gcgtcccact cggcatagct
    25681 cttgccctta ctctggccgg gcttcaccac ggacaatccg ttttccttgc acagcctgtc
    25741 gctggtgcgc cggatatagg catagctctg tttgttggaa atgtacttgc gctgatttac
    25801 catatccacg gcacagaaaa taatgtgatt gtggacgtgg cccttatcaa tatgggtagt
    25861 cagcacatag ggatatttcc cttgcagcac ttcctcggca agctgcttcc cgatctcatg
    25921 ggcctgttcc ggcgtggctt cgccgggggc aaaggattgt atcaggtggt ggcccagatt
    25981 attgcccttt tggtatgcct gcgccagcag catttcaaat tcaatgtccg ctgtttcata
    26041 agagcaggca aaggaggcca ccagcagctt gccgtcagtt ttgtccgggt tctcgatgta
    26101 gtcaagggct tttttcagcg ttgacttgat aggatgtatc tttgtaactg ccatatctgc
    26161 gccagcgccc cctttatatc ctcgatgtcc tgtgcgtaca ccggccccat accgttcagc
    26221 ctctttgcaa tctgattgac gttgacgccg atcttctgta tctcggcggt ctgcgcccgg
    26281 atgtcgctgg tgtccatgtt gacgatatag ccgtcaatga gcatcttccg ggcgtaggct
    26341 gaaaagttct tcgtatgcag cagcgccatt ttctgttcaa tcatagcccg ttcctccggc
    26401 gtcacaggga cgcgcagcac gatttttcgc tttctgtttg ccatgcttca ccgtcctttc
    26461 cattcagggg tttggggatt tccccaacaa gcaaaacgga cgcggcccgg cagggacggg
    26521 gcaggccgtt tttccgggag tggctacact ccctatgctt gctacgttac tgtttctcca
    26581 ctaacaagac gtttccaaag ccccaaacta cccgcaaaat agccctctgg aaagaaaaaa
    26641 gtgcaaaaaa atagaagcta cgctgtgcag ctcccgctaa aagtaaaaca gaggatgcca
    26701 gttacacatc ctccgtttca ttcttcttcg gcttttcaat tagtatggcg ctgtcaatcg
    26761 cgccctcgat gatcggcagg tattcttcgg ggcagagttt cagcttgtgg ctgacccttt
    26821 gccgcagttc gctttcctcc cgcatgatct ccgggttaaa gtagcgttcc acaggaagcc
    26881 cgcaggcttt aataagctgt atgacaaccg gcagactggg aatggcccgt cgttttcgat
    26941 gttggcaaga tagcgccagt caatatttat tttctctgcc attgctttgc gcgaaacgcg
    27001 ctttgcttgc cgggccgctt tcacatccgc gccgaaagtt tcaaagccgg gacaatcttc
    27061 aatattcgcc atatcgcacc tcccacttac attgtatatt tcatactctg cccgtggaat
    27121 gttggtatat gcacctttct taaagtttat atttcacatt ttgtttcttt tattcttcga
    27181 gcaaaagaat tataatgtac cctgtggagg tgtactatgg actacatgac gttgaaagag
    27241 gcaggcgaga aatggggtgt gcccccacga tggataaact actattgtgc tgcgggacgc
    27301 atccccggcg ctgtaaagat ggcgacgatc tggctcattc ccaaaactgc ggaaaagccg
    27361 attgacaggc gtacaaagaa aggaaaggcg gttactgaat agtataatga aaccggcgca
    27421 ttttggatat ggttttgaag agagagaaag catggtattt tgtcacggaa aaactataag
    27481 atgatagatg gcaggctgct ccagaccgat aaaaagtatt ctcatctgaa acagaaagaa
    27541 aagatttaca catggatgta tgaagaagcg aaactttatc atgacagaaa tggaaaatgc
    27601 ccgaaacaaa gacgaggaag ctgctgctgt atcagccgta tatggtagaa ttgaaaaggc
    27661 cggcatctgg attctttatg gtgaagtctc cagacattgg ataactgctg gtctaatgcg
    27721 cctttgagta tggggtgatt gattttaata ccggggaggt acggcttttt gaggaaaata
    27781 ttctgggatt tacatttggc gattattaca tttcctgtaa ctgcaaggac acggatgatg
    27841 aagatatgag gaatatagac ttgctgattt tctactgtct tgaacggtat taggactgaa
    27901 tctgctgcgc ggagtgcggc aagagcgacc ggagggagta cacacaggcc ctgcctgtgt
    27961 gaaaagccat accgcaaggt gcattcgcaa aaaagaggcc gcgcattttg ctgaggcttg
    28021 gggtgtcccc aacaagcaaa acgagaacgc cgcaggcggg caagtggtgg atcagaatat
    28081 ccgtaaagga tattctgatc cattgcttgc cagtattatc gggatgtttt gacaaccgct
    28141 gtaatcgaaa catcccaaac attaagaagg tgttaattat tattatcttg atttaattcg
    28201 tttaaaccaa taatatagat acatacacca tgaaaagaag cgagtatccc aatgacggat
    28261 gattaaaatc cgaaaagaaa tcgctttgaa actacaggga aactacagac tgttatgtta
    28321 tcttcttaaa atggagggat ttttatgtcg atacgaattc tacttgtcga ggatgatgat
    28381 catatctgta atacagtaag ggcgtttctg gctgaggcag gatatcaggt ggatgcctgc
    28441 acagatggaa atgaggcata caccaagttt tacgaaaaca cttatcaact ggttattctt
    28501 gatattatgc tgcccggtat gaacgggcat gaacttttgc gtgaatttcg tgcgaaaaat
    28561 gatactccca ttctgatgat gacagccctg tcggatgacg aaaaccaaat ccgggcgttt
    28621 gatgcagagg cagacgacta tgtaacaaag ccattcaaga tgcagatttt actaaagcgg
    28681 gtggaagccc tgctgcggcg cagcggtgcg ctggcaaagg aaatccgtgt cggcaggctg
    28741 acacttctgc cggaggattt cacggtactt tgtgacggta cagagctgcc cctgacacga
    28801 aaagaatttg aaatcctttt gctgctggtg cagaacaaag gcagaacctt aacgcatgaa
    28861 atcattttgt cacgtatatg gggatatgac tttgagggtg atggcagcac agtccacact
    28921 catatcaaaa atttgcgggc caagctgccg gaaaatatca tcaaaaccat tcgcggtgta
    28981 ggataccgat tggaggaatc ataataatgg aaagaaaagg gattttcatt aaggtttttt
    29041 cctatacgat cattgtcctg ctactgcttg tcggtgtaac agcaacactg tttgcacagc
    29101 aatttgtgtc ttatttcaga gtgatggaat tacagcaaac agtaaaatcc tatcagccat
    29161 tggtggaact gattcagaat agcgataggc ttgatattca agaggtggca gggctgtttc
    29221 actacaataa ccaatccttt gagttttata ttgaagataa agagggaagc gtactctatg
    29281 ccacaccaaa tgccaataca tcaaatagtt ttagacccaa ctttctttat gtggtacata
    29341 gagatgataa tatttcgatt gttgctcaaa gcaaggcagg tgtgggattg ctttatcaag
    29401 ggctgacaat tcggggaatt gttatgattg cgataatggt tgtattcagc cttttatgcg
    29461 cgtatatctt tgcgcggcaa atgacaacgc cgatcaaagc cttagcggac agtgcgaata
    29521 aaatggcaaa cctgaaagat gtaccgccgc cgctggagcg aaaggatgag cttggcgcac
    29581 tggctcatga tatgcattcc atgtatgtca ggctgaaaga aaccatcgca aggctggagg
    29641 atgaaatcgc aagggaacat gagttggagg aaacacagcg atatttcttt gcggcagctt
    29701 ctcatgagct aaaaacgccc atcgcggcta caagcgttct gttggaggga atgcttgaaa
    29761 atatcggtga ctacaaagat cattctaagt atctgcgcga atgcatcaaa atgatggata
    29821 ggcagggcaa aatcatttcc gaaatactgg agcttgtcag cctgaatgat gggagaatcg
    29881 tacccatagc tgaaccgttg gacatagggc gcacggttgc cgagttgctg cccgattttc
    29941 aaaccttggc agaggcaaac aaccagcggt tcgtcacaga tattccagcc gggcaaattg
    30001 tcctgtccga tccgaggctg ctccaaaagg cactatccaa tgtcatattg aatgcagttc
    30061 agaacacgcc gcagggaggc gaggtacgga tatggagtga gcctggtgct gaaaaatgcc
    30121 gcctttttgt tttgaacatg ggcgttcaca ttgatgatac tgcgcttcca aggctgttca
    30181 ccccattcta tcgcattgat caggcgcgaa gcagaaaaag tgggcgaagc agaaaaagtg
    30241 ggcgaagcgg tttaggactt gccatcgtac aaaaaacgct ggatgccatg agcctccagt
    30301 atgcgctgga aaacacctcg gatggcgttt tgttctggct ggatttaccg ctcacatcaa
    30361 cattgtaaat atttaaaact taaatgattt tgggctcttt gtcaaatagg actgatagag
    30421 tgagataaga acatctaagg tagaattcct tttctacttt agatgttttt tgattcatag
    30481 gtaatcagat tatttagtaa gaaaattctg gtcttcattt tccgaaagct tcgaaagcca
    30541 taagcgactc gtttcaatgc tttgatgtgg gtatgcagat tttctatttt ggcatttgaa
    30601 taaggcaatt cgagggctaa acgaatgccg gattcatagt ttataaaagc tttttttata
    30661 gaatgcagtt cttttggaac ggaattgggc atcgttctta caagtttaaa gaaagtgtcc
    30721 gcctctttgt cgtgaaacgc ttgaagaatt tcttgatagt aaaaataggc gattcgtaat
    30781 tcgtcagaga tcgaaagcag acgatccacc acttcacttt cggtgagata cgcccaacca
    30841 aaattgcgcc atttggtcca tttgtcataa acaagcttgt cctgtcgttt gatcagaagc
    30901 cgagacaacg cctttaattg tcgataatat ttggcttgtg ttggatcgtt tcgatcaaag
    30961 cttttcatga ttcgtacgcg aatatcctca aatttacgaa tgagatgttt gacaatgtga
    31021 aaacgatcca caacgagttt tgcctttgga aaacattcct ttatcagaga ggcataagaa
    31081 acattcatgt ccgtcacgat gacctttacc ttcaatcgtg cgcgtcgttc aaattgcata
    31141 aaataagaaa cgagagcctt tttcttccgt gaaggaagaa tatccagtaa ttttccagta
    31201 tcgccatcca tacaagaaaa ggagtaggga ccgacttgat ttttcagtga acgaaattca
    31261 tccattaata aacaacgcgg taaccaattt ctttttactt ttgtcatggg gatcagagaa
    31321 gcgagtgtcc gagaaacggt cgaccaagaa acgccgcaat gcttagcaat tgtcgtcatt
    31381 gcttgttttt cagttagctc ttctaaaatt ttatagcgca cttgtttagc gataaagcag
    31441 tttctatcga caatgtaggt attcgccgta aaataggtgt ggcagccacg acagtggtag
    31501 cgttgtttcg ctaaagcaag ataagtcagt tggttcgcac atttattaag ttgaatgagc
    31561 gattttttct ttccgttctt aacgatcatg ccttcatgat tcatctgttt acacaaagga
    31621 cagcgacgaa tttctttact taacgtcgca gaaacaacaa gactcttgat attcttaatg
    31681 ctcttcgatt ccacatttgt gatgaaaatg tttttatctt tgattccaag tagtagtttg
    31741 atatgatgaa gatcaggcat acagaacgct cctttgattg tgttgtggtg attcaattct
    31801 aacggagctt ctgtatgttt tgttttttca tgctcaaaag ggaccgatag aatgattttc
    31861 tatc
//
LOCUS       DADVXK010000022        29956 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.022, whole genome shotgun sequence.
ACCESSION   DADVXK010000022 DADVXK010000000
VERSION     DADVXK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.022"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(229..1173)
                     /locus_tag="KB909_000945"
     CDS             complement(229..1173)
                     /locus_tag="KB909_000945"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6836997.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1469..2413)
                     /locus_tag="KB909_000946"
     CDS             complement(1469..2413)
                     /locus_tag="KB909_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6836998.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2634..3848
                     /locus_tag="KB909_000947"
     CDS             2634..3848
                     /locus_tag="KB909_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6836999.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3870..5885
                     /locus_tag="KB909_000948"
     CDS             3870..5885
                     /locus_tag="KB909_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBB6837000.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5968..7341)
                     /locus_tag="KB909_000949"
     CDS             complement(5968..7341)
                     /locus_tag="KB909_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6837001.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7367..7651)
                     /locus_tag="KB909_000950"
     CDS             complement(7367..7651)
                     /locus_tag="KB909_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837002.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7653..9668)
                     /locus_tag="KB909_000951"
     CDS             complement(7653..9668)
                     /locus_tag="KB909_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6837003.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9847..10152)
                     /locus_tag="KB909_000952"
     CDS             complement(9847..10152)
                     /locus_tag="KB909_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBB6837004.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10241..11272)
                     /locus_tag="KB909_000953"
     CDS             complement(10241..11272)
                     /locus_tag="KB909_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6837005.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11479..12354
                     /locus_tag="KB909_000954"
     CDS             11479..12354
                     /locus_tag="KB909_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6837006.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12506..13348)
                     /locus_tag="KB909_000955"
     CDS             complement(12506..13348)
                     /locus_tag="KB909_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6837007.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13440..15317)
                     /locus_tag="KB909_000956"
     CDS             complement(13440..15317)
                     /locus_tag="KB909_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6837008.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15314..16735)
                     /locus_tag="KB909_000957"
     CDS             complement(15314..16735)
                     /locus_tag="KB909_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6837009.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16738..20127)
                     /locus_tag="KB909_000958"
     CDS             complement(16738..20127)
                     /locus_tag="KB909_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6837010.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20384..21775
                     /locus_tag="KB909_000959"
     CDS             20384..21775
                     /locus_tag="KB909_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837011.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21848..22495)
                     /locus_tag="KB909_000960"
     CDS             complement(21848..22495)
                     /locus_tag="KB909_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6837012.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22503..23189)
                     /locus_tag="KB909_000961"
     CDS             complement(22503..23189)
                     /locus_tag="KB909_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837013.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23195..24268)
                     /locus_tag="KB909_000962"
     CDS             complement(23195..24268)
                     /locus_tag="KB909_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837014.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24490..25164
                     /locus_tag="KB909_000963"
     CDS             24490..25164
                     /locus_tag="KB909_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6837015.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25169..26509
                     /locus_tag="KB909_000964"
     CDS             25169..26509
                     /locus_tag="KB909_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6837016.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26658..27644)
                     /locus_tag="KB909_000965"
     CDS             complement(26658..27644)
                     /locus_tag="KB909_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBB6837017.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28368..29399
                     /locus_tag="KB909_000966"
     CDS             28368..29399
                     /locus_tag="KB909_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6837018.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29508..29933
                     /locus_tag="KB909_000967"
                     /pseudo
     CDS             29508..29933
                     /locus_tag="KB909_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
BASE COUNT         8874 a         5615 c         5390 g        10077 t
ORIGIN      
        1 gttgcggaag gattttttaa ttaaccacag ataaacattg ataacgattc gcttattgta
       61 atcaacagat taaatttcat atgttcatat gtacggatac attttcggac cgattaattt
      121 taaccattct atttatttgc ttacctatta gatatcaata aaaaactgct taacagctat
      181 ttcagctgtt aagcagtttt aggattttta gttcatattc attgtttctt ataatacagt
      241 gttcaatact tctcttaaag cacttgttga tttgctgaac attgcttttt cttcttcgtt
      301 gattgataat tcaacaactt cacgaacacc attttcgtca acgattgatg gcacacctgt
      361 aaagatatct ttttcgtcgt attcaccagt taaataagca gatacaggca atacagcttg
      421 ttcgttattc aagatagctt ttacgatacg tgcagtactc ataccaatac catagtaagt
      481 tgctttttta cgatcaatga tctcataagc agcattacgg actttatcag caatcacatc
      541 taattcatct tgggcaatac gatggtcttt ttctacaatt tcaaacactg gtttaccacc
      601 gacagttgta tgtgaccatg cagcaacttc tgaatcacca tgttcaccta agatatagcc
      661 gtggacgctg cgtgggtcaa cttttaattt caatgcgatt tctttacgga aacgagttgt
      721 atccaatgtt gttccagtac cgataacacg tgatgttggc agaccagatt cgttccaagc
      781 gatatatgtc aaaatatcta ctgggtttga agcaacaacg ataataccgt cgaatcctga
      841 tcccatgatt tcttttacga tttggcgcat gattgacgca tttgttttaa ctaaatctaa
      901 acgagattga ccaggttttt ggttgatacc agctgtgata acaacgatat cagcatcttt
      961 acattcttca tagccacctg accatacagc cacattttca tcgccccaag ccataccatc
     1021 taaaaggtcc aatgcttccc cttctgcttt ttcttgattc acatcgatca atactaattc
     1081 attagagatt ccttggttga tcattgcata agcgatactt gttccaacaa aacctgtacc
     1141 gacgattact actttacgac ttgttttttt catgaataaa cagctccttt tcataactat
     1201 ttgttacttt catgaaaagt atagtcttgt ttattcattt tatcaacatg ttaattataa
     1261 tagttgttat tataattttt gatggaaacg aattcctgaa tacgcataac agataaatga
     1321 caaatgttta cacctatatc ccctgataat acaaccaaaa gtttagaact gaaaataaat
     1381 ccaaaaaaat tcgctgcaac gatataataa gacagcaatc gcacctaaaa caattttcct
     1441 tcatatgctt tagtgaaaga ttttcttctt aatgtttatt tctccattca ttgggagtac
     1501 atgttgaata cttcttgaat aatttgaata aagaagtcgt ttgtttatat ccgatacgat
     1561 tagcgatttc ttccaacgaa aaactcgttt cttgaatcag ttccaacgca aagtcgaatt
     1621 ttttctttag aaccagttct tgaaaggaag catcaaaata cattttcaat ttattactaa
     1681 gatagaccgg attgtagcca aaatgagctg ctgtttcttt taacgtacaa gaagtaaaat
     1741 gcttatcgat ataatctaat actctaagca tctcattttc tgcgcatcca tctgctgatg
     1801 aaaagctttg ttgttctaat aaatgagtca attcgatcag taatagtgat gtatagagat
     1861 ttaacgaacg gatcttatga ctgtatgtat caaaataaat caacagcata ttttcaatca
     1921 aatgcgtcaa acgacttgtt tttccgccgc gaaaatgaat gaattgtgta tgttcccctt
     1981 tttcttttga tgcatttatc aaaaaagaag aaagtagatt atttgtgctt gccaaatgat
     2041 tcaatatctc tgtagataag gtttcttctt ttaataagat gttgattaaa atatcctctt
     2101 gccctgtgta ttcgattctt tgagtagctt ctttatcaat gatcaccacg tcactttctt
     2161 ccatctctat cctttctcca ttaataattt gtaaacatgt accgctatac atataattga
     2221 tttcaacaaa atcatgtgta tgctcgggaa cttccgcata tcgacggtgt ttactgatat
     2281 gaatatttcc ctgttgaaat agatcccctc ggtggatttt tggcggtgtc tgaagatggt
     2341 aagctaagtt taaatcattg atattcattc cttgttcacg ctgcagagtt tcgattgatt
     2401 cttcgttacg caaaaaaaat gtctaattca gctagttcca attgactccc tcctttttgt
     2461 aagcggtttc tttcgcttat tagttcacgc tgtactgcta ttatatgcaa agctattttt
     2521 ggtttcataa agactttcta tggttgggac atgaacttcc tgtgattccg ctattgagag
     2581 aataaccact tcatactata tttttgataa gcgcttacaa aaatgaaagg aacatgctta
     2641 tgaataaaaa gatgatgaaa ttttctctgc tgtcagtctc tcttattttg acttctgctg
     2701 gtgcagtcac gtctgcaatt cccagtatgt cagctactta tgccacgcgt tctttatctg
     2761 ctgttgaatt attaacgact gctccctctt ttatggtcac tatttttgtt ttgattagta
     2821 gttttattgc taggaaaatc ggacaaaaac aaactgtgat catcggatta gtgattgcat
     2881 cgatttgtgg tatcctcccc ctcttctcac aaagttacag tattgtctta gcttcaagag
     2941 ctggactagg tattggcttt ggattgatca attctttggc agtcagcatg attgctgcct
     3001 tttatcacgg agatgaacga gcctctatga ttggttttca aagtgcattt caaggatttg
     3061 gtgcagcttt aatgacattt gttgcaggac agctagtaca gttcggttgg caatatacct
     3121 ttttagtcta cgccatcagc ttacctattc ttgtcttgtt tgttttgttt gttcctacac
     3181 ctgaaacaac tgaacttcaa tcgcatggca cagccccaac aagacaagta atcaaaacga
     3241 atcctaaaat gattagttat ggtatttttc tcttgctggt catcgtggta tataatgctg
     3301 tatcgattaa attagccaca gtcctgacga cttattctct aggaaacgaa actaatgcag
     3361 cgaatatctt aacaatcatg caattggcaa gtatggctgc cggagtttgt tttggctggc
     3421 ttcagacaaa agcacatcgc tatatgctta cactttcttt actactgatg ggaatcggct
     3481 ttgtattgat tgccactgtg ataaacctgt atgtgattgg gtttggtgcg atcctaacag
     3541 gaatttcttt ttcgttattc attccttact tattcaacca agtaagtatc caagcgccca
     3601 agtacgcgga gagtttcaat acttcaatct tattggttgg cgctaattta ggtactttca
     3661 ttgcaccata tggtttgctc tttctctctt ttgcttctct tgggagtaaa acacttgctg
     3721 ttttcgtcaa tggcagtatc ttgctgttga ttagcgcgct tattagcctt ctagtagtac
     3781 acaggacgaa tagaaagaca gtgataagag tagatgaaga aataaaagaa caattgacaa
     3841 caaaataaat ttgatggagg tcgtgtaaaa tgacaaatga aaaacataaa gatagatggc
     3901 tttggtatcc tggagacttt gagatccgcc atggactgct acaaaatttc caacgggaag
     3961 aacgaggttt tgactggcca gcgtactggt acatggatga ttgccatcgg aacgtcaagt
     4021 ttaagagata ttactttctt gatcaacctt ccatgtttaa agtgacgatc caaggagttg
     4081 ggtatgtaga aattaatgga caaaaacatc catgtggaaa atggctgact tgtccagctg
     4141 gtaaagcaaa aattcgtatc tttgtaggac atacatcagg gctaccagcg atgtttatcg
     4201 agggagacga agtaaaatca gatattggct ggacagcaag taattttatt gaagaatatc
     4261 cagctggctg gagtccgctt tatgtcgata tcgcaaaaga tccaaatcaa atctattatc
     4321 aaaaagaatg cgtccatcca gtcactgaaa cggagattgg cggaggaatc ttattcgatt
     4381 ttgggcgagc agtgaatggc tgtgtagaac taatatctct ggatgaccat atcgaatcta
     4441 tcactctatg ttatggagag tccgatgtag aagctatgga tatcgattat tgctactata
     4501 agcaaatagg aatgacaaga aaaatgaaag ctcgtaaacg cgcttttcgc tatttgttta
     4561 taccagaggt ttctactgga atggttcaac ttcaagtttt tcatgaattt ttatctcttt
     4621 cgaaacaagc tgctttttca agcgattctt ctttactgaa tcagatctgg tcagtatcag
     4681 aagaagcctt caagttatgt agtgatttgt tttttatcga cggtatcaaa cgagatcgct
     4741 ggatttggtc tggagatgcg tatcaatcat tcatgatcaa tcaatatctt ttttttgacg
     4801 aggaaatcaa taaacgaacg atattagcat taagaggaca aaatgaaatc aagcagcata
     4861 tgaatactat cgttgactat tcgatcttgt ggttgattgg tatcgaaaac cactatatga
     4921 tgacgaaaga ctatgaattt ttacgcatcg tctaccctaa gatgcaatca ttaatgagat
     4981 acttgatgga gcaaacgaat gaattagggt ttatttatgg gagagcaaaa gattggatat
     5041 ttattgattg gtctgaaatg gataaagaag gaacgcttgc tgcagaacaa gtcttattac
     5101 tgaaagccta tcattccatg atcacttgcg gagatatctt agctgaaaca tatggagaga
     5161 acgaaaatta tcatactcat ctctatcaag aaaaatatca actattgaaa caaaacctat
     5221 ttgactactt ttgggatgaa gaacttggcg cttttatcga ttgctatgaa tctgggagaa
     5281 gaaatgtgac gcgtcatgcg aatattttcg ctgttttatt cgattttgct aacaaagacc
     5341 aacagcaatc gatcttaaag aatgtcttat tgaatgacac tatcacacag attactactc
     5401 catatttcaa attctatgaa caagatgctt tatgcaaact cggacagacg aatatcgtct
     5461 accaaacgat tcttgattat tggggaggga tgttatctca tgatgcggta actttctggg
     5521 aagaatacga ccctactcaa acaggaaatg aaaagtacag tatgtatgga gatccttatg
     5581 gaaaaagctt atgccatgca tggggagcaa gcccaatcta tcttttagga cgctatttta
     5641 tcggtttgta tccaacaaag ccaggttatg aagaatttat gatacaacct aatctagatt
     5701 catttgaaac actgaattgt acgctaccta tcaaagatgg aaagatttcg cttgaaaaaa
     5761 caaaagataa gatcgtgatt acttctgata gaacaggcgg aacagtgaaa atgaatggta
     5821 aaagttatcc tcttctagca aaacagccac ttgtcttaac aagctattca aaaataaatg
     5881 cataaaacaa aaaactgctt gcgacatatc agaagacttt aaatcttctt ctgatattgt
     5941 ccaagcaatt tttattttga agtttgctta attctgttct ttagaaacaa tgtttgttct
     6001 ttttccggca aaaagaaagc tagataatac gacaagtaaa aagaaagcga tgattccaac
     6061 tgtcaaggct atttgaccgt attctcctag tttcccaagt acaagtcctg gtactagata
     6121 atcagtatcg gcaaatgtag aagaagcgat tttaagatct cctaatactg gaaggataaa
     6181 taatggcagc caactaatca ataagctatt gaaagcagaa cctaataccg cccctcttct
     6241 accgccagtc gagttgccga agacaccaga agcagctccg cagaagaaat gtcctactac
     6301 cccaggaatg ataactgtag tttgcaagcc tatcatagca aacatggata gtgttcctac
     6361 aaagaagcta acaaaaaagc caattaatac agcattaggt gcatatggaa aaacgatagg
     6421 aacatctaat gctggtttag aatcgggtac gagtttttta gcaatccctt ggaatgctgg
     6481 aacgatttct gccaacacca ttcgaacccc ttgaaggacg ataacaaacc cagctgtgaa
     6541 tgttccagct tggatcagtg caaagattac agcgttgtct ccattgctta gttctctttc
     6601 aacaaatcca ggaccagcta acaaagcaag tgcgacatat acgatcgaca tcaagagcat
     6661 gatcgataca gtagaatctc gcaaaaagct gaaactttta ggaatcttta tgtcctctgt
     6721 agaacggtct ttgtttccaa aaaactttcc gatccatcca ctagaagcat aaccgatatt
     6781 tccggtatgc cctaacgcaa cttgattgtt tccagtgatg ttcttcataa acggttgaca
     6841 aagagcaggc gtaatagtta atagtgttcc ttcgaagacc ccgcctaata agatcatcca
     6901 caaatttgca gtaaaccccg cgcttactaa aatgactgct gttagacaag aaacataaag
     6961 cattgcttga cctgtaagaa aaatgaattt atatcttgtg aatctagcaa gtaaaatatt
     7021 cacgatcatc cctactagca tgatcaaagc agtaggtgta ccgtattgtt gcaaagcaat
     7081 cgccactact gcttcattgc taggaactac tccttgagta tgcagagctg tttggaacat
     7141 cgaagcaaaa ggggttagtg aattactgat taaaccagca ccgccgatca gtactaggaa
     7201 tccgacaaat gttttgatag ttccttggat cacttctgaa aatttcttct tctgaagaac
     7261 gagaccaagc agtgcaatca aagaaacgag gatggagggc tgactgacga ttgacacaaa
     7321 caaattcaac aatttatcca ttgatagttc ctcccttgaa tcatttttat tcttttgaca
     7381 agatcttcgt tactttttct tttacttctt cgctgtcaat gatcgattgc aaaggtacga
     7441 gcttttcatc aggtatagaa gttagcgtat ctttcaaaga atgctcaatg aagaaataat
     7501 cagccatatc gctagataca cttccaacat ccgtatgact tacttcaaac tcgtccacat
     7561 ctgctccaag atctgcaagt gcttgtttga tgttcatctc taccataaaa cttgttccta
     7621 atccactttg acatactgca aaaattttca tatcattcgt ctccttttct tatgatcgct
     7681 aatatttctt cttttgttga tgcgtgtaat aaatcttgaa gattttgttt attagaaagt
     7741 agctttgtta aatttgccaa agcccgaaga tgtgcctcat tatcgatagc agctaaacag
     7801 atgaacaaac taatgggatg ggctggatta tcaagcagat ccacaggttg ttgaagtttc
     7861 agcaaagaca tccctacttc gtttacgcca tcttctggac gagcatgagg taatgcgatg
     7921 tgatcgccaa tatggataaa cgcaccatac tgctccacgc gctcgatcat agctttgata
     7981 taactttctt ctattttatt ttctgataat agcggctgtg cggcaaatgt gattgcttct
     8041 tgccagtttt ttggttgatc cgataattgg atcatttctt ctgttaataa ttcagatagc
     8101 ataggacgtt gatcctcctt cttttctaaa agtttgttca ttttacgatt taatacttga
     8161 tagagctttt cttcgtctac gccttctttt aattcgatat aaggcagtag cgccgacaac
     8221 aattcttggg cagaaggcat tgaaaatcct ggtatcagcc aatctctttg tacttgattg
     8281 atcagctgat ttttttccaa gtcagtcatg attggatgca gaacatagag agactttttc
     8341 ttatcagtaa gtgtgagagg tacagtagaa aaaataatat cgtaagaagt ttcgtcaacc
     8401 tcgtgtaagc ggtcagctga attagtctct gtaaaaaaga tcatcgggaa taattgctga
     8461 agttcacttt ttaagatcaa tgaagagcta atgccacttg gacagacgat cacggctctt
     8521 atttttctat ttctttcttc tgcgtccgct tttctgatct ctccgccaaa tagtatagtg
     8581 aaaaaaccaa tctcttcttc agggatgctc ttccctattc gtctttctaa cggaagtaat
     8641 gcttttcttg tcatttcgta gatggaagca tattgatgct taatttgatc gatcatcaca
     8701 ttaggtaaat aaaaagaata ggaaatacga aaataggcag ggaccaagtg ataaaagaca
     8761 ttcatcaata attcacgaaa cgaagcaaat tctacggcca tcaggaattc catgcgatgg
     8821 atgacttctg aagaacattc cagcaaaaaa tcaagtgcag gctcctggac atctccttca
     8881 acgatcgatg ctaagcaaag agagaaaaat ataatctccg aattttgatg ttcggaatag
     8941 ccaaggccag tcaatacttg tcgactaatg tcagtgactg caagagaagc caacagttca
     9001 gcatctttta ccagttccat ggatgttttt ccaattcgaa tggttgtcaa actcaaataa
     9061 taagctaatt catccattcg atttggtgcg aatcgaagat ctgatagtga aatcgtttta
     9121 tctagcaaat ctctaacttt ggcgtaataa tcaatggaaa gggttgcggt taaatacgtg
     9181 agcccaaatc ttccagcaag tgactgcatc aaacgagcag tgcgattttt tgcttctctt
     9241 cttaatattg cttctgaccc tagcagccta aaaccagttt tcctagtata cgacagctga
     9301 caatcttcca cttctaattc atttcttatc tttttgatat ctgacaggac tgtcccttta
     9361 gaaacctgaa gaaaatcttg aaaatgaaaa acagaaacag acgttgcagt cgaataaacc
     9421 atcaaataaa gaagatctct tcgctcttgt tcggtataca cagcttcaaa tcgagtaata
     9481 tccaaaaatt tttctgccca gtcgattgct cggaatttct ttatacggat acgggtatca
     9541 tccacatatt cggcaaaagg agttaattgt ttgatcgcct cgcttgtatt tacttcgatg
     9601 atctctgctg ctttttctag actgatttct cttggtgttt tcaggagata actaattttg
     9661 tagttcacag cgctgttcac ctcctactta tattctagta tggtagcgct tttaaatcga
     9721 ggggtgtttg gtacaactta cagttggatt ttttttacga ctgtaccgaa cgatttctat
     9781 cgaatggata cagaaaaaaa gcaggtgacc aaatgtctcc tgcttttatg aattgatttc
     9841 gtccgatcaa tgatgatcat gtttattttt tgaggtcagt tcttcaaatt tttctttgac
     9901 atcttcaacc gctttttcga tatctttttc aaagtgattg ggctcattag gctttgtttc
     9961 ctcttctaca gaatttgaac cagataaagc tgtttcttta ttttctgttt caccagagtt
    10021 tgtgccagct aatgattctt ctttgtcttc tgtttcacca gaattagttc ctgctaaagc
    10081 cacttcttct tctgttttag gggccattga acctcttaat cgtttgtgtt tttcaccgtc
    10141 ataatttgtc atgttggttc ctcctagtag ttctatactt tttcatcgta caataagaca
    10201 gtttatgcgt caaaaaacaa acccgattct tacaaatatg tcatattttt ccttctgatt
    10261 cttgaatgct tttgattcct tcttccaaaa ttttcatttg taagattgtt tcttcatctt
    10321 tgatgacttt ttctgcgcca ttaactaatg tctcgtaaat cccttcgtag acacggctgt
    10381 aatcaccaac ctcggaaatt actttttctt catgataact cccttgttca tctatatagg
    10441 tcaatacacc ataatgttcg ggcaaatcga taccaaagtc ttcatgatca ggcatgtaaa
    10501 acattttcag atgttcttct tgtcgatctt ttgtttgttt cacgaacatc cctttttttc
    10561 cgtaaacgac gaaacttgga cgttctttga tgcggaaata actggatttt atcgaaattt
    10621 tcatatttcc atagaaaaaa tccagatcga agtaatcatt cattcgtcct ttccctaaaa
    10681 gttgacgtac atcatagctg atatcatctg gttcgccgaa ataagaaaga acttgatcta
    10741 ctgtatgaca agcatgtcca tataaatagc tgttcgcagt agaaaattca tgcgtatttt
    10801 ctggtacttc cggtctgaaa taatcataat gcatttctac ttctaaaata tcccctaatt
    10861 ttccgctttc gattactttt tggactgtca agaagtcaga atcgaaccgt ctgttttggt
    10921 aacattggat aaatagacct ttttcttttg ctaatgcaaa taactcttct gcttcctttg
    10981 acgtttctgc aaaaggtttc tctactagta cattcttacc atgttcgagt gccatttttc
    11041 catattcata atgaaattga ctaggtgtag tgatgacaac taattggatc tcaggatcat
    11101 cccaaagatc agacagctga tcagtatatt cgatgtcttc gaatgttttc cacactggtt
    11161 cagatgggga aaaaattttt ttgatattga ttttgttcgt aagttttctt gaaaaaggca
    11221 aatgatagcg atttgtactc tttccattgc caagataagc gattgtaagc atgagtggtg
    11281 cctcctttta ttgatgtttt cagtatatcc tagaaaagcg cagaaagtat ttataatagc
    11341 tattctggta aaaaagttca gaaaaacact tgttatcatt cggtttggtg aaattaatgt
    11401 tcaaagtaag gataaaaatc aaaaagatag tagcggaacc aagtgtttat cagtaagata
    11461 gaatttggag gtcagatcat gcttattgaa gaaaaactaa caaaacaaga gttgtttacc
    11521 acgacagaga aacggattgt cgattacatc cgtaggaata tcgaagctgc agtctacatg
    11581 acgattgaag aattagcaaa agctacgtat acttcccatt cagctatcat tcgtttatgc
    11641 aaaaaaatgg gattcagcgg atttaaagaa ttccgtttcg agctggggcg ggaagttcat
    11701 caattgattg ctcagttcaa tcaaacgatt gatcctaatt ttcctttttc aagtgaagat
    11761 agcactcagc aaattgcaaa gaaaatggcg gatttatcga tccagtcaat aaaaaaagca
    11821 caattgcaga ttgaacatga agatttagat caaatcggta aagtattgaa caaggcacag
    11881 cgaatctttc tttttgcaaa aggtgattct caaatcacgg caaggaaatt ccagaataaa
    11941 atggtcaagt tgaataagtt tttgatcatg gctgaagaat acagtgattc ttcttggaat
    12001 gcagccaatt tgactagcga ggattgcgcc atttttatta gctacagcgg tcgcatccat
    12061 cattatgaac gaataatgac ctatttgaag catgtagagg cccctacctt gctgattacc
    12121 ggaaatcagc attcagaaat ggccaaacag gctgatatgt gtcttgttat atcgcaggag
    12181 gaatatgatt ttgctaaagt agcgactttc tcctctcaaa ttgccttcga ttacgtatta
    12241 aatacgttat tctcagtgat atattctcaa aattttgaag agaatatccg caacttgaaa
    12301 aacaaacaag aattgatgca aaaaggcctt cttaaagaat atcggaaaac ttaagaaaag
    12361 atcctcattt agtaataaga aagatagtgt ttgataggct ctctttgata tcatcataaa
    12421 aacaggctga agttttcttt ttcaaacctc agcctgtttg tttacggaac gattcgaata
    12481 gatatattat agaaatgagg aatagctaac ttctgtttct tattttgaac gattgacgaa
    12541 aaagatatat aagaaggagg aaaatcagta tacatgcagc taacaatcca tacaggaaaa
    12601 atcgtttgtt ctcggatact ttctgtactt ctttttgaac ttcttttgca tgataaggaa
    12661 cccggtgccc tctgacaagt aagcgatgac tgttgaccat ataaggtgta caagttagga
    12721 gtgtcacgaa atcctgccct ttttcgattc tcagatcttt tgtatcagtc ggttctaccg
    12781 tcttgatctg atcgacttga taagcgagtg tccgtccatt gatttcgata tagaaagaat
    12841 cacctaaagt cagtttcggt aagtctgtga acaactttgc ttgaggcagt cctcgatggc
    12901 tggaaataac ggcatgtgta ttttctcccc ccgtaggata agacgttcct tccaataatg
    12961 aggcaccttt ttctagcagc acagtattcg tttcatcaaa aattggcaaa tggacattga
    13021 tctcagggat cgtcaaaata ccgatcgtat gtttctcaaa ataggttcta tcctttttcg
    13081 caggttcttt tttcttagta aagggatctg cacctggatt tccaccttct tttgctaatt
    13141 gctggttttt ctttgtcatg ttttcttgga ttttagccat gacttcttca ttttctttga
    13201 ccgcttgttg ctgataatga gagatgatct gctgatccag ataattattc agcgcgtcgc
    13261 taacaaatgg ataagctagt atccctattc ctgagagaag caagaaaagc atcagcagat
    13321 ctagaagttt ccttttcttt ggtttcattt gtgttctcct tgtgatgact gtttgataat
    13381 aaaagaaaaa ggagcatttg cgtaatccgc tgctcctttt tccaattctt gcaaaaagac
    13441 taaatctgac tgtgcttgcg tctagcaaag tacagtccag caatcagtag aaggactact
    13501 cctgcaccga tatacacata gattccctta ccgcctgttg aaggaagtgt acctttgtgt
    13561 ttatttggta ttttttcagg agaaatcaac tgtcctgctg ttacataaga ttgttcatcg
    13621 atagtaaatg ctacacggtt tgttaatgga acatattttt ctggcgcttt cgtttcttcc
    13681 agatagtacg tgccatattt tagacctgtc acatcgatta aaccgttact tgtggttgta
    13741 aaaaccgttg ctgattcttt cgccgatacc cagctgacgg cttttgtgga tgggtcgatc
    13801 gataaatatt tcgctgtgtc actatcttga tcacgaacga cgaattctgc tccagcaagt
    13861 gtttggtctg atgtaacgtc accatctact ttaacaaatc gtttgccccc agtaacgaca
    13921 tcgactgacg gtggtgtttg atcatttgta tgcccgttat cgacatttgc ttggttagaa
    13981 aatcctttgg ttggatctgc tttttcgttc aaatgcatat agtaaacgaa tttcaatgta
    14041 ccgccaggag ttaatgaagg aatataattc ggatcaactg aaaccgtgaa tccgtctgtt
    14101 tgctcagtga cagaataatt tactgggtcg atttctttat ttccatcata taaggcataa
    14161 gcatacgttc ctgaagaatc attatcaaat gttaaagcag cgtcatgagt atcgataagt
    14221 ttgaatgttg tgtacttgtt ttgcgttcct tctttatcag cgatacctaa tgggatattg
    14281 acagaaatct catattgaat tttttcaccg attgcgacat cttttccatt caattgaggt
    14341 gttgttttat caactttaga cgtatcattt ttgatggtct tttctactgg tgtttggcta
    14401 tttgccagga tctcaaaagg cgtgattgtt tgcttttcaa tcatttccgc attatcagga
    14461 gcttttactt cttctaaatt atattttcca acttctaaat gattaacgat caactggcct
    14521 ttttcaatag atgcctcggc aaagtcattg ttgccgatgt cataagaatg accagtaatg
    14581 aaatgtttgg ctttggtttg atcagttgtc caagtgtaca atccatctgt gacactttgg
    14641 atgtattttt tgacgcttgg tgttccttct tctttagaaa taataaattc tgctccattt
    14701 agtgcttcgt tttcggcagt accgattttt gtaactttca acgttccatc attaccgact
    14761 gtatttttag ggtagagatg gatagtatct agttcttctg tcccgtattt ataagagcca
    14821 tctgcttgtt tgatcatctc atatacaggg aaagctaaaa ccatgtttgc ggcagctgac
    14881 actccgtctt ttggttcttc tttgatcgtg tagactgcat ctttcccatt ttgtttttta
    14941 ggtaaagata aagtgacatt tccatcagca tctgtcgttc ctgaagcaac tggtgtacca
    15001 ggagtcaaag actggactgc ttgttttgct gcatccacgg acgctccttt atctcgttgc
    15061 gcataaaatt cttgagtgac gttataaact gaaaatgaaa tatcggctaa tccttggtat
    15121 tgatcgaatt cgctcatttc tttcccgctg ttttggatta aaggatcggg taaatcagtc
    15181 attttctttt tatgaaggat gacttgagct gctgtctcct ctgcaaacac tttttttgcg
    15241 ccgaagctgt ttgtgagtaa tggtaaaata aggaaaagga ctcctaacat aacgtttatt
    15301 tttttatgat ttttcatttt ttcactcctg ttcttttttt gataaacaac cagattgcaa
    15361 agcttgcgaa taccatacca acaacgccta aaagtgtatt tttcgtttcg tttgtttttg
    15421 gaagaaatgg acggctattt tcttttttat tgactacttt caatatactg tccgcctctt
    15481 tatcctcaga aagaaaagtt gaaatggtaa acggaatttc tgtttcactt aaaatataac
    15541 cagaaggtgc ttcgatctct tttaatcgat aacttcctgt tttcaacccg gaaattgaaa
    15601 aagcgccatt tttatcggaa atcaggtgaa gcgcatctga ttcgttcttt gtccacttgt
    15661 atccgttggc tgtttgctgg aggtaatttc ctgctttgtt tttaataagg aatactgcgc
    15721 cagctaatcg tttatctggt ttatttgtct cgattttgac aaattgctta ctccctgtat
    15781 atacagagac tttctttgta ctgacaccaa aaccaaaatc cagtgttccg ttgttgttga
    15841 tttccttgtt cgcctgtgct gtactgctta gctgcatctg ataagaaatg gtcagttttt
    15901 ttccagcata tttttccaac gaagggatcg aaaataaaac atcaaatccg tgaggtttct
    15961 tgtgtatgac aaagccttct gtcagctttt ctccattcga tgaaatcgtt aaactattag
    16021 gtaaaaacgt taatgcttca tccgcactat ctgacaattc gaacttttga tagtcaagga
    16081 tatttacagg aattgtcgta tgcaaggaat aagtgatttt ttcaccaatc gtaaaatcat
    16141 ttctaggctc ttctaatacc ttctcaaaag gtggatcagg gtagtcgttt tcttcatttt
    16201 taggatacaa atggatagtt gaaagttttt gattgttttg tccatgtaca ggaagaacaa
    16261 ctaccatatt ctctgccttt tctttgacga cttctggtac tttggattca atgaaaagat
    16321 acgctttatc tcttttttct tgatctttag cggccagaga aaaagaagcg ataccatctt
    16381 cgttgttaag agttgtagtt gttgcttctg cggtaaacat accggaagac gcaccgtttt
    16441 ttgcgatctc tgcttgtgct tcttctaccg ttttgccctt ttcccgtaga tggtaaaaag
    16501 aatctgtgac atcataaact tggaatgtga caccatttaa tcctcgatac gtttgtaata
    16561 aagctttttc ttgtccgtca tttggatgat ttttcggcag ttgcccgttt gggaaaagca
    16621 atttgtgtaa agtaatctga accatttctg tttctgtttc tgttgctacc tgagtaaaag
    16681 ctggtttaaa tagtaacaag aagagacaca tactaagcca accaagtttt ttcatattta
    16741 gctgccccct ctttcttttt tcaaaaaaag ataccaaata gaaaacgcac aaccaatcat
    16801 ccctactaga tagattccta aacggccaat tcctcccgtt tcaggtaatg gtacttttgc
    16861 ctgattcgtg atgtctaaag aaatctggtt gtttttggct cctggtgaca gaacagattc
    16921 atgatcttgt ccatccactt gaattgaccc atcttcgtgt ataactatag taactggctc
    16981 ttttagacct tggtatcctt ctggtgtaaa agtttcggtc agcgtataag ttccaggttt
    17041 taaattttcg aatagaaagg tatctgtttc ttgtccatct tttggcgatt ctaagtccat
    17101 ttctggtccc tgcagtctga attttgctcc ttttaatgtc tgtccgttgt cttctttttt
    17161 gtgtaccgtt agatcaaacg cttttagtcg attttgatga gtgagcgtcc atacattatt
    17221 tgtcatctcg gtattttttc ccgtgtaaat gatttttcca tatttatcga tttggaattc
    17281 ataatttccc ggcgaagtat catatccggc aggaccagct gtttcaacga ctcgatattt
    17341 accaggtgtg agtgaatcaa aactggcaag acctttttca ttcgttgttt ggctgtcaat
    17401 tggctgataa gtaccatttg cttctttttt ctgtagggaa aatgctgctc ctttaagatt
    17461 tatctctttg tccgtccctt gcatcgcata cttacgtact gctacaggaa cttcaacaaa
    17521 aggattttca atagtcaact ggatcgtatc atcggaagta gtgactgttt ttccatcaat
    17581 ggttaccgta ccatcagaag cgatcttgat ttcccaagta gtctttttgc ttaatccatg
    17641 cccttctgga gcttttgttt ctgtcagcgt ataggtcatt tctttttgca atttgacatt
    17701 ttctggaaga gaataggttc cgtcgccatg atctgttagt aaagtatcaa tagaatctcc
    17761 tgttaatttg aaaacagcgc caataagatc cttttcacct gtagaggaat ttttcgttat
    17821 tttcaagttt aacggtgtga attgtttagt atttttccat gtcattgcat ctatttgttg
    17881 agaatcgtat cctggtacag gtaattcttt gattgtttgg taactgaatg cttgaccttg
    17941 attattgtat tgaggtagtg ataatatctc ttgataactt tctccgctat ttgcagataa
    18001 tttgtcaatg tctgcacgtt cccacgtatt tgttgtatct ttagctggtt taatgattcg
    18061 aatatatccg tttttccaag ctgcagcatt tgtcgtatgt tcccgttgaa tctcaaaagt
    18121 aacttgatct ggacgatcag ctagattgtt gtcaaattct tcccataact ttttgatgtg
    18181 aagactgact ccgggagctt tagcagatgg tataccgaat tcagctaatt cattggtatc
    18241 aatgtttggc tggaaagttg tcctgccgtt catttgatac cagaaatttg gatggaagtc
    18301 ctcattttct gtttggattc tcacttggta atggatttgg atttcttggt cttttcctaa
    18361 atagatctga ttgctcttga tggtatttcc ttctatggaa atagatggag tgaccgttgt
    18421 aggacttgtc cccacactct tgactgaaag tgtaccaggc tgataaatga atggttctgc
    18481 gattggatca tttatttgtc cattgcttac agttgctgag atctgtacag cttttttggc
    18541 taggtattca gagatatctg ttgcatgatc agctgattca tagtaaagat cgcctttttc
    18601 atctgatgaa accatttgtc gcatacgaga ctctacttct gcttttgaga gaccagctgc
    18661 cggatcgctt tgaagttgga tgccaagacc atgtatttcg attcctcgtt ctttgagtgc
    18721 catcgcttct ccgatggttg cgataaacgt actgtcgatt cttctggata gattgttttg
    18781 gtcaggtgca tcatagattc ttgagattag agaagtattt cccggccgat cttgcgtatt
    18841 agaaaactga gttccgtaat aattgctgct tgattgtgcg tgtacccgct gtactttata
    18901 ggaaaatgtt ggtacaccat ccgtcagcaa aacgatcact tttttatgtc catttggaac
    18961 ggatagcatg cttcctgcat ctcttagtgc tttttgtgta aaagtaccac catttgtccg
    19021 tgaaggtgta atggatttta cttgattttt cactgaatca aatgaaccca tctgtactgc
    19081 accgttactg tagctatatc cttcgcttga gtagccgaca tatcccatat tgattttgtc
    19141 tgtgataccg ctatctgcta aagtatcgac aaaacgatcg acaccaatct ttacttcacc
    19201 gatccgatta ttgtcgttca tacttcctga ccagtctacg accaatacga gatcaagagg
    19261 cgtgatatct ttttgtacat ttccacgagc attcaaataa acatcaaaca atccgggtgt
    19321 acttgtttcc tttgcatact ttcgtatcgc atagtctgct tgattaccgg ttcctccata
    19381 ttcgatatac gaatgggtcc gatcattagg atctccattc caagaattta taccatccca
    19441 ttgatttgtt ccgtttttat tgccttgatg atcaagaaca tttgtatttc ctgtaggttg
    19501 ccaactggct ttaggataag tgccctgatc atctgttgta tattctgtag gaatcgtttg
    19561 attagatggc acactcacag ctggcaagga taatgtaggc aatgtaaatg ggctgacaga
    19621 attttcgttt tcttttgatg attcttcttc tatttcgtct ggctttggta ctgacacatc
    19681 tgtatctttc ttattttctg tctcatcaat aatgtcatat tctttattat cgacgatcag
    19741 cttgtttgcc tggctgtggt aaagtgctgg atcgattgga aaactcagat cgatagtttg
    19801 tttagtgttt gatgagattt ccaacgtaat tttcccgcta tttacctgat aagcatagcc
    19861 atctccttct tttctttcca catcacttaa gtaattttcg actagaccaa tttctttttc
    19921 tatcttttca gcactggtgt tattcgcatt tagcttgatg ttcagtgctt tttttccaga
    19981 ctgatccgaa atgacttcag ctgaaattgt ttctaaaact gttggatcat ctgtagtgtc
    20041 tgctattgca gataatggca caaagtttga taaactcaat attatcagca tgaaaataac
    20101 tttcagtttc ttccctgtgg tcgtcatttt tcccctcctt tttctttttt tctgttttga
    20161 cgtgaatagt gaaaattatt aaaataaaca ggcgttacat aattttattt attttaatat
    20221 gataattatt atacgaaggg cgctaaaggg aatcacacca attttcatac caattggttt
    20281 catttatgaa gttgattcct tcgattaatg agcgtttcat tgaaagaaaa gggttgaggg
    20341 agaaaaacat atgatcaggt tgttggaagg aaactataga aagatggaaa aaatcattcg
    20401 aattctgtcc atttctgaca agtggatgac taaaaaagaa cttgccaaac gaattggtag
    20461 ttcagaatct acatttgtaa ggtatatcga agagatcaaa atccgctggg gaacggatgt
    20521 aacgattcaa tcttcacaaa aattggggta tcgtcttgaa catttgaatg taccagctta
    20581 tttaaatgtt ctgatggaaa tgtcgcaaag ttctacaaac agtcgtttat taaatgagat
    20641 tattgtcaat ccgggtaaaa cgattgagta ttattgtgaa aaaatttcca tcagccggtc
    20701 ttcttttaca cgtaagttga aacaatgcaa tcaaatttta gaaagctatt tattaaaagt
    20761 gatcgttgac caaggttttc agttaactag ccttaaaagt gagctccagt tgcgtatctt
    20821 tgttaccttt ttctttttaa gttactacgg aagacgcacg ttgccatttc caatcgaaaa
    20881 aaagaagatc aaagaaatta tggtcaagaa taattgtcag atgaatttgt ttcaggaaga
    20941 aagcccatat gagcaatctt tctttattat gtattttgtt gtgcatctca tgagagaatc
    21001 ccaaggaact ccatttgaat ggaaagctgg agactcttat gtacagttga taaatatcga
    21061 taaaaaagac ttcttaatct tgaaaaatct cttaggaaaa ttgaagtaca gcagctatat
    21121 aaaagtagtg aactattttg tcaatacgat tttttcagaa ttttcggaga aagaaaaaaa
    21181 tgaaatcagt gagcagatac gaaaaaatat gtcctactgt tcgttttcat ccgctgattg
    21241 caaagaaaaa aacgaagaat atgttgttca attattaacg caaatttatt ttttctcccg
    21301 tattttccca tacgatacga ctcatttgac gatccgtgca acttactttg cacagcagat
    21361 gcaacaccgc cagatacgtc tatatgctgg atttcgtgca gaacttcaat tttattccac
    21421 tctactgaat cagaatctga tttattattt atctagctat atcttttgga tgcttatcgg
    21481 taatcctgaa attcaccatt atacttctga taaaaaaata ctgattatca gcgacttaag
    21541 tcttcgacat agtcaatata ttgaagaata tatcagtgat attcttgctg tgcataaaat
    21601 tcactctgag acaactgcta ttactgaaga tcagctgtcg aaatacaatc ttctcgagta
    21661 tgatctgatc gttacgaatc aacccatttt gaatgcccat gttcctcata tattgattga
    21721 tgatagtgtg tcattcgcaa atgaagaaga actcatccgc ttattcgagt tatgaataat
    21781 caaaaaacag ctatgtataa accaccctga taaaaatttc aggacaaata cacatagctg
    21841 tttcttttta ttgtattcct tcagcaatcc aacgagattt atagcgaaag tcttttaaca
    21901 actcttcttt tgtccaatta tttgcaatga gatccgtcaa agtgttcatt acgagggtca
    21961 tggaaaagta taggaaacta actgcttctt ccgacgattg aatggagaaa tgattgattc
    22021 ttaataattc cagccatttt tcgttcattg gagaatcagc cgatagttct ctacgtttgg
    22081 ttgtctgctg atcatttcgc tgggttaaca agtataacct ttgccaatag atactttcgt
    22141 gatctaagtc gcagcaccac tctaaatatt tttcgatccc caaaaagaaa tgttgtttgt
    22201 tttcgctaat gaattttaag atatcttgat ggactatgtg agaactgctt ttgatcgtat
    22261 acaaataagc atcttccaaa tcttgaaaat atttataaaa agcaccgcgc gacatcccca
    22321 tcttgtcaac gatttctgag actttgactt ggctgatgtg ctgtgagcaa aatatctcca
    22381 gtaataggtc atcgattctc tgtttctttg cgttcgataa attgaaaaaa gtttcttttg
    22441 gcatccacat ctctccttta tctctgatta tacgtggata gcccttcatt gtcatgaagg
    22501 attcattcct tctttttctc ttcttctgtc aagtacccat cttccattcg ataaacgcga
    22561 tcactccatt gaatcatacg gacatcatga gtaaccataa tagtcgcttt ttgtttctca
    22621 tgagcttctt taactagtaa tttgacgact tcatatgcat gatctgtatc caaactagct
    22681 gttggttcgt ctgctaagat caagcttggc tcattatata aagcgcgagc aattgccact
    22741 ctctgtcttt ctccaccaga aaggtcttta ggataactat ttttaagtga ctggatatct
    22801 aaagattgca gcaaggaatc gatttttgtt gaatcttctt tttttgaagt aacttggtca
    22861 actagttcaa attgttcctt taccgttaaa aaaggaatca aattagagct ttggagaata
    22921 aatcctattt ctttaaagcg taaatctgct cgtttttttt ctggaagctc agttagtgag
    22981 tgaccgttga tcactatttc tccggaagtc ggtgtttgca atcctcctga aatggtaagg
    23041 aaagtacttt tacctgaacc agaaggacca atgatgctga cgaattctcc ttcctttaca
    23101 taaaaatcaa ttgctttcaa agctgagacc tttgtatgac cagaaccaaa tgttttggta
    23161 acttttttca tcgttaatat ttttttcatt tttattaacc tcctattgct gtaattgggt
    23221 ctactttggt tatcgtacgt atcgaaaaca atccgcctag cattgcgaca atgatcaaaa
    23281 tcccactata tagcaaccat tgtgaccaaa aaacagcaaa aggcatcgcg cttggtaaaa
    23341 tcagactagt caaataagca aacaaaagag caagcagaac gcctaccacc ccaacaataa
    23401 aggactgtgc tactaaagat ttagcgatga agaaattttt gatcccttgt gctttcatta
    23461 ctccaaaaat agcagtcttc tgaagtgtca tcacgtacat gaaaataccg accacggcag
    23521 caaccactaa gaacaaaaag tatatcatcg catttaaggt catattttgg gcagaatagc
    23581 caggaatact ttcaatgaat gtcccaatag ttaataactg tagacccttc gatgcttttt
    23641 ctttcgaaat tttagctgaa tcctttatta cgatcccatt gatcggctgt tcttcttcag
    23701 aagcaaacgg ctgttgtcca tacttcaaag cagtccacgt atctagggac gcatagatga
    23761 cgggagaaac tgtgtaataa gtttcaggaa agataccgac aatcgtcaaa ggatcgtcgt
    23821 aactgccaat tttgatcgta tctccaattt tatagcctga atcagccaga ttttgagaga
    23881 tgatgatttc attctttgtt ttaaattcat gccctttcgt gagttttggt aataaaaatg
    23941 cttctttcgt tgtgccgaaa actgtaacat tttctttgtt ttttcctttg attgctccgc
    24001 tgtacaatcc gattggtgct ttctctcctc cttcaatgta tttcagatct cctcttgtta
    24061 attgtgaagc tgcaaatact tgatttgcat cctccgacaa aacaatctct tgtgcgtccc
    24121 aatcatcgat tgctttttta aactcttctg aaagtccatt cgctagtcct gacaacatga
    24181 atacgacata cgcaatcaag aacataatac cgacgatcaa gccatatcgt aatttagaat
    24241 agcgaatttc tttgatagct agaaacattt gtttttcctc cctatgatag attgatagtg
    24301 acaaaatgtc acttgttgaa tagtgtaact ctaaagtgac aatttgtcac ttgtgttgtt
    24361 tttttcttat caataaattg tctaagacat ctttcgataa aaccttaaca tgagtcataa
    24421 aaaatttatt taagccttat ttatgctttc catgataaac taaagtgacc aaatcaatga
    24481 ggtgggaaaa tgattaaact attagtagta gaagacgata aagtattatc caataatata
    24541 aaagaaatac tcgctgcaat cggcgagata acacaagttt atgatggtag tgaaggactg
    24601 ttcgagttgg aaagtggagt ttatgatctt gcaatcttgg atttgatgat gccggaaatg
    24661 aatggatatg aagtgttagc aaaaatacgg aaagaaaaaa tacagactcc agtattgatt
    24721 ttgactgcaa aagatagttt ggaagataag attgaaggat ttgaacgagg tgcagatgat
    24781 tatctaacaa aacctttcta tcgagaagaa ctgatcatgc gcgtgaaagc attattgaaa
    24841 cgctcgctag gtctctttga tgaaaatgtt ctgaagtata aggatatcag ttgtgattta
    24901 aaaagcaatg aagtcttgta taaagaacaa gttttgccca tacaaggaaa agagtttgaa
    24961 ttgctcgttt attttttaca aaataaggga atcattttga caaaagagca gatatttgac
    25021 cggatctggg gatttgattc tgatacgacg attacagtta ttgaagttta tatgagcaac
    25081 ttacgaaaac atctgcgaag tactggattg gataaagaaa tcaaaacctt acgtaatgtc
    25141 ggttatatac tgcaaagggt gtgatgcaat gaatggagat attacacgaa agcaacgtag
    25201 tcgctttttt gcgacaaatg tagcagcatt tgcttttatc ttttttcttt tgggattcat
    25261 tactttacag atattaaacc aatctgcata cagagaaaca gatctgtcat tagagaaaat
    25321 aaattttgat tctcgaacag tacaattaga gatacaaaga tatcagcaag gcgatccctt
    25381 tttaaacccg actcaaacgg aacaaaacag aacaaacatg gaacagccat taatggaacc
    25441 atcaaatgac cgttttaaca ctcaagtgat cttgtggtct aaaaatggtg agatattgaa
    25501 taaagcagct attggtgggc gtttcaacca aatcaaagaa ttaaaaatgg atacgaaaaa
    25561 tctgaatacc atccaaaata ttgaattaaa tgaagacagt ggctcatctg ccctctcttt
    25621 ccgttcgatt acgaaaaaag cggagacgaa tcaagatggc gttgcctaca tccaaatttt
    25681 agaaaataca aatcaaatca agaattcatt agcgactttt cgcacgatta tgattttgtg
    25741 tatgattgtt ttttggattc tctctattgg tatcagttat tacttgtcta gtctaagcat
    25801 gcgccctatt attctttctt ggagaagaca aaaagaattt gttgagaatg cttctcatga
    25861 attgcgcaca ccgttaacga ttattcaaaa tagtttggaa catcttttta ccaagcctaa
    25921 tcatactatt attgaagaat ccgaaagcat cgctcaagca ttgtcagaga cgaggcgcct
    25981 cactggattg acttcggatt tgctgacaat cgctcggaat gattctgatc agcagctgct
    26041 ttcaaagcaa atgatcaata cacaagaata tatcgaacaa cttgttaaac catttcaaga
    26101 gatggccatc atagatggaa aagagtttat tctccataac gatgcaacat tagaagtacc
    26161 aattgatgaa aaaaaaatcc atcaagtttt ggttattttg ctggataatg cattaaaata
    26221 tacgaatcca gaagataaga tcattttgga ttcatctgtt aaccataaag aatggctgat
    26281 tcacgtaaag aatactggcc cttctatcag tgaagaagat caagcaagga tttttgatcg
    26341 attttatcgg gaagatcaat ctcgggcgaa agagactggc ggatacgggc ttggcttggc
    26401 aattgcaaaa caggtaatcg aacagcatca tggacagatt tctgtatcca attatcttcc
    26461 acaaggagtc gattttaaag tccaattgcc gttgaagcct aaaaaataat gcttatccct
    26521 aaaaaagggc tgtgacaaaa atcttgtcac agcccttttt tgttgcgaat aaacggtgtt
    26581 ccagaagtag cttcttcgga aataagccga aatttcttta agctgaccac ttctgtcaca
    26641 acctctttag cttacgctta cgatttttta ttgcggtctt caatgtgtac atcaccgctt
    26701 gtgtcaatat ccaattcttc tcggctaaca tcttctgtca ctttttcaac atcttcatgt
    26761 tcttctttat gaatcccaac ttcttcacga ataactgtat gtttgcttac atctacttgc
    26821 tcttctttga ttgggatagt aatcgtgtca tcttccaatt tttcgtctgt tccctgtgaa
    26881 gattgatctg ttactggttt gcgttcgatg acgatttctt cacgtttgac cggtacttct
    26941 accgtttcag tatcgttgac cacatgtttg tggatgtcga cttctccagt tgtcacatca
    27001 tgtgtattta catctaattt ttcttctttt agttgaattg tatcatcatc tagatttggt
    27061 ttgcgatcga tgtcttcagt cttgcttgta cccattgtat cagtctcgcc aggtacgtcc
    27121 atcggatcag ttcctggtgt catattcaat ggatccgttg tattttgaaa gcctgtcgtg
    27181 ccacctacgt ccattggatc tgttccagtg ccagtttcta atccagtccc cattgtgctt
    27241 gctgggctaa cagtatcttg tgtatccatt gtatcttctg ttgtttctgg ctgacgatag
    27301 ccttttactg tgatgacaaa ttttccatca gaaatatctc ctctatattg atataaagga
    27361 tcattttctg gtgtagccgt ctcagaatca taggtatcaa aagaaaaagt atcttttatt
    27421 ttttcccata aagaacggtc ttcttcacca tccatccgat tttcatctgt ttcaacatct
    27481 ataccagaca atccgtcaaa tcctagtcta gatgctgctt catcagtagt ataaataacg
    27541 atatcatctc gttcataccc ttcgttacgc aaccgttcaa ttactgataa tgcttcttcc
    27601 ctcgtactat agcttccgat gaccgttaaa tttttctctt ccatgtaaat tcctcctagc
    27661 aaatagattt atgattggta tattgttact tataaattta ttctatagga gacgattgtt
    27721 ttctacaaat atttagattg gaatttgatt aaaacaattt aattgaaatt tgaaaacatt
    27781 tatgttaatg aaagtcatat tctaataaaa tgtcatttgt ttctatatga atttttatga
    27841 aaaatttcat ataatttcca ctcgttgtga tggtttaatt tatccaatcc atcaataagc
    27901 aaacaactta tataaaaaag gattaattct caatataatt gctcctacca tagaataaat
    27961 cttcatgtaa agtaatgaag taccaactat ttctaatact tctttaagaa ttatcccaac
    28021 aatatcgtta gacaaaccat tattgaataa atggagagcc aatcgattct gaaaaaatgt
    28081 tttctaattt ttcggaaata aaagaaagag cctcctgcca ttagaacgaa ccaaatccat
    28141 ttcattgctc atgaagtaac cacatagcta aaaagaggat aaatcaatta aaagatcaaa
    28201 agaatgactg cactaataaa ataactaaaa atgtatcttc ttacttcata tcttttagct
    28261 agtacttagt taaaaatttg cttcctaaga tcaagacaaa ctgtctatct tcatttgatg
    28321 aaatgcggta aaatatagaa aatgaacact attggaggga atttgtaatg gacagcaaaa
    28381 ctagaaaaca actgcaagaa aagttaaagc aacgtacaca cttgctccct tccgtctttc
    28441 aacagttttt agaagaaaat cgttcttccc tttcattagg cagtcgctat gaatacgcaa
    28501 aagattttca tctgtttact gattatttga gaaaagtatt ttctgaagaa gtggatgatc
    28561 agctgattat ccatttagaa aaacaagatt atcagaattt cttagctaaa atctatcgac
    28621 atactcgttc gttccaaact acagcgaacc aagaaacgga gcaattgttt gaaaatagct
    28681 attacgggat ttcaaggaag caatattcat taaatcattt tttacgattt ttgtatcaaa
    28741 aaggactgat tgaagaagag atttctcttt tgggtacaag tttaccggaa acaaccaaag
    28801 cagctccgcg atatatcgat gcagaacttt tcaaagattt tgagcatttg tttatcccga
    28861 ttgaaggctt tcaaacaagc agagaagcta gctttgaaga aaagaataga ccgaggaacc
    28921 ttgcaattac tgccattctt ctgtattgcg gattaaagat ccatgaagta gtagaactta
    28981 aacgtaaaga tgtatctttg accaagcaga ttcttaatct gaatagaaaa gaaaacagac
    29041 tgaataaagt accaatacca aaagaagcga tgccatttct ggagaactat tttaagttaa
    29101 cagcacaaaa tacggacgaa aattcttttg tttttcgttc ctcacatgat cagcaaattt
    29161 ctcctcggac tattcgccaa attttgagca aaattacagt atataaaaac gtatcgccag
    29221 aactatgcag aaaaacatat cgttattatg cagaactata tttagatgat gctgacgcgg
    29281 taaattattt atgtggtaat cgatacctct catcccattc ttttcaagat atctgggaaa
    29341 agatggttga tttttcttat cacgaattag cggcattcgt tcgggtttct tccatataaa
    29401 acaaatgtat gatctttttt tcacaataaa ctatgttatt atataaagga ttatgttacg
    29461 attatcttga atttgtatat tacttaacaa aagataatgg agtgtgaatg atggagacca
    29521 taacgtattc ccctttgaac ttatttacga attttcaaga agctgcagct aacttttccg
    29581 agaccccgat tatctttgat gagccacttt cagctttccc agaattagga cttgaaacaa
    29641 cttacaaaaa atgctgcgaa agtgtgttga aacgggctta tcaattggct catcttggag
    29701 tgaaatccgg agacaaagtt attatttata agagttccgc ttttgacaca taccttctag
    29761 ctgtttctgt gtcttacctt ggtgcagtgc ctgtcatgac ttcttatcat ctaccaacaa
    29821 caacaatgga agtatttatc gatcgtttag aagacccttt cattttattt gatgatgaga
    29881 caaaaaagcg agtgagagaa atttcaaatg gaacaaaatc aaaacagatt cctaacccgt
    29941 ggtgctagtt aatttt
//
LOCUS       DADVXK010000023        29682 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.023, whole genome shotgun sequence.
ACCESSION   DADVXK010000023 DADVXK010000000
VERSION     DADVXK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.023"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..637)
                     /locus_tag="KB909_000968"
     CDS             complement(<1..637)
                     /locus_tag="KB909_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837019.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSF"
     gene            complement(786..1499)
                     /locus_tag="KB909_000969"
     CDS             complement(786..1499)
                     /locus_tag="KB909_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6837020.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            1674..3098
                     /locus_tag="KB909_000970"
     CDS             1674..3098
                     /locus_tag="KB909_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6837021.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            3397..4104
                     /locus_tag="KB909_000971"
     CDS             3397..4104
                     /locus_tag="KB909_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6837022.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            4091..4414
                     /locus_tag="KB909_000972"
     CDS             4091..4414
                     /locus_tag="KB909_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6837023.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(4503..5540)
                     /locus_tag="KB909_000973"
     CDS             complement(4503..5540)
                     /locus_tag="KB909_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6837024.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(5861..6844)
                     /locus_tag="KB909_000974"
     CDS             complement(5861..6844)
                     /locus_tag="KB909_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBB6837025.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(7259..8029)
                     /locus_tag="KB909_000975"
     CDS             complement(7259..8029)
                     /locus_tag="KB909_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837026.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(8022..8957)
                     /locus_tag="KB909_000976"
     CDS             complement(8022..8957)
                     /locus_tag="KB909_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837027.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(9273..10922)
                     /locus_tag="KB909_000977"
     CDS             complement(9273..10922)
                     /locus_tag="KB909_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6837028.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(11039..13642)
                     /locus_tag="KB909_000978"
     CDS             complement(11039..13642)
                     /locus_tag="KB909_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6837029.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(13654..14703)
                     /locus_tag="KB909_000979"
     CDS             complement(13654..14703)
                     /locus_tag="KB909_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBB6837030.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(14729..15043)
                     /locus_tag="KB909_000980"
     CDS             complement(14729..15043)
                     /locus_tag="KB909_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBB6837031.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(15059..15505)
                     /locus_tag="KB909_000981"
     CDS             complement(15059..15505)
                     /locus_tag="KB909_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6837032.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(15506..17428)
                     /locus_tag="KB909_000982"
     CDS             complement(15506..17428)
                     /locus_tag="KB909_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBB6837033.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(17640..18536)
                     /locus_tag="KB909_000983"
     CDS             complement(17640..18536)
                     /locus_tag="KB909_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6837034.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(18529..19209)
                     /locus_tag="KB909_000984"
     CDS             complement(18529..19209)
                     /locus_tag="KB909_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6837035.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(19210..19992)
                     /locus_tag="KB909_000985"
     CDS             complement(19210..19992)
                     /locus_tag="KB909_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837036.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(19985..20902)
                     /locus_tag="KB909_000986"
     CDS             complement(19985..20902)
                     /locus_tag="KB909_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6837037.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(21066..21389)
                     /locus_tag="KB909_000987"
     CDS             complement(21066..21389)
                     /locus_tag="KB909_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837038.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            22177..25404
                     /gene="fss3"
                     /locus_tag="KB909_000988"
     CDS             22177..25404
                     /gene="fss3"
                     /locus_tag="KB909_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6837039.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            25517..25831
                     /locus_tag="KB909_000989"
     CDS             25517..25831
                     /locus_tag="KB909_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6837040.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            25844..26218
                     /locus_tag="KB909_000990"
     CDS             25844..26218
                     /locus_tag="KB909_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6837041.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            26228..26563
                     /locus_tag="KB909_000991"
     CDS             26228..26563
                     /locus_tag="KB909_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBB6837042.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            26646..27986
                     /locus_tag="KB909_000992"
     CDS             26646..27986
                     /locus_tag="KB909_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6837043.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            28064..28738
                     /locus_tag="KB909_000993"
     CDS             28064..28738
                     /locus_tag="KB909_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6837044.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            28731..28895
                     /locus_tag="KB909_000994"
     CDS             28731..28895
                     /locus_tag="KB909_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837045.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            28971..29405
                     /gene="dcm"
                     /locus_tag="KB909_000995"
     CDS             28971..29405
                     /gene="dcm"
                     /locus_tag="KB909_000995"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBB6837046.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            29406..>29682
                     /locus_tag="KB909_000996"
     CDS             29406..>29682
                     /locus_tag="KB909_000996"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBB6837047.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLL"
BASE COUNT         9114 a         5808 c         5337 g         9423 t
ORIGIN      
        1 taaatgacaa taaagcaaac gaggtaatcg taataatgat tgggattaat acattaaaag
       61 actttaaaac agcgggagga atatttccgg atagctgaat ctgtagtttc ttattattag
      121 aaagtttaat aaataattct gtagccgcta atccaacaaa tatacctaca aacattcctg
      181 aagctcctgt ataggatata ggtatcacac ccgtcacttc aacagcttta tccgcatttt
      241 caggagtaaa catcatctgc ataggtgtta atacaacaaa tgtcgaaata gcaactaata
      301 ccgctgcaat atgatttgta taatttctgc ttgcacacat atgataagat actgctgcta
      361 caactaataa tgtagttatg cttaatgtac cattggcaat tgaagtacca atttgttgta
      421 acgtggtcaa tgtactagta tcgacaattt cccccatgaa tcctgttggt tctaagatca
      481 ctgaattaat aagtgtcaca aatcctgcta acatcataaa tggcataaat gtagcaaacg
      541 catctcgcaa agttcttaaa tggatctgat tccccaactt agtcgcaact ataccaaatt
      601 tttcaaatac aatgtccttc ctgctacttt tgcccatatt ttttctcctt tatgcttatt
      661 gtaatcgatt actttttcca cccaaataat acatcactta tcaaaaaaag taaatacttt
      721 taattaaata tatatatctt ttttagtata aaaaaataag ctctgaaaaa ataattttcc
      781 cgagcttatt tttcaacaaa aacagcttca aaaacaaagt cttgatataa atgtctcgat
      841 accgaatact cgaaaggttt accagacgat agagcaacaa ctttgtctat ctcaatcata
      901 aattcacctg gatctatttt taatattttt gcgtcaaatt cattcgcagt atctcctttg
      961 atacgtatgt gcgaagtctt tatttccaga cccagttcat ttgtgatata agcatataca
     1021 gatttcttta aatgttttgg ttccaagcct ggtatgactg ctaatggcat gaatgtttgc
     1081 tcaatcgagt atggttgaca atcaataaaa cggcttcgta caatattata tacatagtct
     1141 tttacactga tacttaattt atcagctact tttttcgatg gaagttcaat tgagaaagta
     1201 tggatttctg aatctacgtg ttcttcacca accacgctaa acaaaccttc gtttggacca
     1261 agaactcgtg agttatcaat tggtgttctg acgacttcag tcccataccc acttctactt
     1321 cgcaaaactc cttcggaaac aagtaagtct acgcctttct ttactgttaa cttgcttgta
     1381 tgataaataa ctgccaattc atctcctgta ggaagtttct caccaatttt atactctcca
     1441 tttacaattt ttttctttat atctaagtaa atttccatat acttcgcaat ttttttcaat
     1501 ggtgaccctc caatcaaaaa catatcttca tctatacttt aacataaata aaccgataaa
     1561 atccacatca aaattataca cacaataaaa aagatatata tatttaaaca aaactattta
     1621 ctttaagttg taagcggtgt tatcattaag tggaaacagg aggtaaaaaa attatgacaa
     1681 ctatgaaaaa gctaactttt ccagatgatt tttggtgggg ttccgcttgg tcagctgagc
     1741 aagcagaagg aaaaggagaa acaggaaaag cagagactat ctgggatcgc tggtttaaag
     1801 aacaacctta ccggttttat caacgaatcg attcctctat tacaaccgat cacatccatc
     1861 aatataaaga agatatagaa ctaatgaaaa aaactgggca taactccttt cgcgtttcta
     1921 tttcttgggc acgaatgttt ccaaatggcg gtaccggaaa agtaaatccc aaagccattt
     1981 ctttctatcg aaaattattt tccgaaatga ataataacgg aatcaaagta tttgccaact
     2041 tatatcattt tgacatgcct gctactcttc aagataaagg aggatgggaa tcacgtgaag
     2101 tagttgatgc ttatgttcat tacgctgaaa cttgttttaa agaatttggt gacttagttt
     2161 gtcattggtt taccttcaat gaaccacttg ggcctatttt aggtacttat cttgaagatt
     2221 ttcattatcc aaacctcatt gactttaaac gcggagcgca agcagcattc ttcactatac
     2281 ttgcacacgc aaaagcaata caagtattta aagaactagc tcttcctagt aaaataggcg
     2341 ttattctaaa tttgagtcct acttttcctc gtagtcaaaa tcctgctgat gtgaaagcag
     2401 cagaaatcgc tgatttattt tatacgcgga gctttttaga tcctatggtt aaagggaatt
     2461 tttctaaaaa gcttatcctg ttattacaag aatataatca gcttcctgaa gattatacga
     2521 aagaagatct tgtatgtatc tacgaaaata ccgctcaaat tcttggacta aactattacg
     2581 agccacgtcg cgtcaaatct cgttcttcta tggtggatac atctagtcca tttttaccag
     2641 agtggttttt cgaaccacat atcatgcctg gacgacgaat gaacgaatac cggggatggg
     2701 aaatttacga aaaaggaatt tatgatttgt gcatggatat caagaaccat tatggaaaca
     2761 tcgaagcatt tatctcggag aacggaatgg gcgttgcgga tgaagaacgt ttcatggatg
     2821 atacagggca aataattgat gattatcgga ttgagtatat caaagatcat cttgcttact
     2881 tatggaaggc aataaatgaa ggatgtaaca ttaaggggta tcatctttgg acatttattg
     2941 attgctggtc atggatcaac gcctataaaa accgatatgg gctggtttca ctcgacctta
     3001 ctactcaaaa aagaacaatt aaaaaaagtg gcgaatttta caagcaatta agtgatacaa
     3061 atggatttag atacgatgta gacttgttag ttgaataata ttctaaaatt ccacttgaag
     3121 tgaacacatt agaaaacaag aataatgaga aataccaata acaaatactt tttcttcata
     3181 cttcatttat acttgtcagt ataagagact gtgacaaatg tagtgatcct cagaagttag
     3241 gtctggaaat ctaacttgag aagatttttt taaactacgt ccagtctttt ttatttgttt
     3301 aaaattgaag ttgacaagtc ttcattaaaa atttagaata ttcacaagtt tgacgacaat
     3361 tatgaaaatt tatgtcgtgc taaaggagtt ttgttattgg atgaaaagtt agatataaaa
     3421 actgcgatca aagacacgtt acctaccgtt tttggttata tcggtattgg acttgcattt
     3481 ggtatcgttg ggaaagctgc cgggtttcat ccgctggtcg tcacgttgat gtccctgctg
     3541 atctatgctg gttctgccca atttatcacg gtcagcatgc ttgctagcca tagtccactg
     3601 ctctccatcg ttctctcgac ctttctagtc aattcccgaa tgattctgat gagtatgacg
     3661 attgctcctt atttcaagaa aaatcggctg cttcaaaatc tgctgattgg cacattgctg
     3721 acagatgaaa gtttcgcact gggaatgaat aaattgaact atactggaca aaagttaaac
     3781 tttcgttgga tgaatacagc taattggatt tcttatttga cgtgggtggg ttcttctctt
     3841 gttggcgcac ttttagggaa ttttattact gatccgaaaa agtttggttt ggatttcgcc
     3901 atcgtcgcta tgtttatcgg gttactttat cttcaagtca tttctgatag aaacacctct
     3961 aaacgattac agttgatcct gattggtctc actttgattc tggtatatgt cggactgatt
     4021 tttatcccaa gtaacttagt gattttagtt gtaacactga ttgggtgcgg attgggggtg
     4081 tggatcaaac atgccttctt ttgagtttac attgctgact attttaggtt gtactttagc
     4141 aacttggctt tctaggatcc taccatttgt cttactgaaa aaattcgatt tgccgcaacc
     4201 gttgcttgag tatttaagtt ttgtcccgat cgtcattatg tctgctttat ggttcagcag
     4261 tctatttacc caaaatatcg gacatctgcc gcagatcaat ctcgaaaatg ctttggcttc
     4321 agttcctaca cttttagctg ctattctttc aaaaagctta ttggtgatcg tcttggtagg
     4381 aattctttcc ctttcgttga ttcgcttatt ataaataaaa aaacaagagc ttatggcaaa
     4441 ttactgtcat gcgctcttgt ttttatcaaa gtcaaataag aaaaaaatcg gcgtattctt
     4501 gcttatccgt tgaacggacc actaacaacg acttttccta atatatgtcc tgtttctacg
     4561 tctttggttg cttgtttcaa gttcttcgca ttcatcccat ctgaatagac cttgctcaat
     4621 gtactgcgga taatcccttc atttgctaaa gcagcaatgt gcgctaaagc ttctccttgc
     4681 gtttcgattt catagttata gtctgtttta gcgaacatat actcccagtc gaagctgata
     4741 gattggtttt tccaaacacc tatatctaac ggctctttga tccctacgat cgttcccaca
     4801 tgtccaaatg gtcggacaag gtgtttgatt tgatcaaagt agcgggtaat atcgaataat
     4861 acagcgacat actctacttg atcgattcct aattcacgaa aacttttact taagtcgtga
     4921 tgataatcga ttggatagtc tacacctgtt tttttcagcc attcaaaatt cttcggactt
     4981 gcagtcgcgt agacttctag gccagcccaa tgcgctagtt gattcaaaat cgaaccgacg
     5041 cccccagctc cgttgatcac taagattttt ttcccgcggt tggcattttc ttctggagtc
     5101 agaccaaatt tttcaaataa caattcataa gcggtcaatg aggtcaacgg caaggctgcg
     5161 gcttcttcat ctgaaagatt ttttggtgca agagcgacaa tacgttcgtc aaccagttgg
     5221 tattcttgat tgcttcctgc tcttgtcgtt gtacctgcgt aaaaaacgcg atcgccgaca
     5281 gaaaattttt gcacttcatc acctacagca acaactttcc cgactccatc aaaccctaag
     5341 atacgtaaag catttcttat cccgttatct tggcgaagtt tcgtatcgac aggattaaca
     5401 gatactgcgt tgacttttac cagaagatcc cgtgaactgg gtacaggtat ctgttctttt
     5461 tcatcaataa agctttttgg atcatcgatc gacaaccctt cataaaaacc gactaccttc
     5521 attaattcct tttctgacat acgaattcct ccttagcttc atcaagttgg agcatccata
     5581 cagttttcat ttcaatatat atagtatgct atttgttcca cttttattca tcataattat
     5641 tctcttactt aaagtaaact atttgcactt ttttggttaa aaaagaggtt gcgacaagac
     5701 ttttgtcaca acctctttta aacggtgttc aatcaactga ccctcggtat tcgctcaaaa
     5761 aacgacaaaa tatgaggagc tatttttgtt tggctgttct tattacttga tgcaggacag
     5821 ctttttcacg acctctaatt cacggtgttc aagcaagaaa tcattgttca ctgaaaagcg
     5881 ttggatgttc tttttcaaag gtgtctaaga tctctcgtac ttcatcagta gatttcgtat
     5941 tcatcaactg aactcgcaag tcatttgctc ctggaaatcc tttgatatag attttaaaga
     6001 aacgatgtag tcctgtgatg gaacgcggga tgatttctga ataatgatct tgcagatcta
     6061 gttgcagacg aagtagtccg atcagttctt tttctgtatg ttccctcggt tctttttcaa
     6121 atgcataagg attcttgaaa atcccccggc caatcatgat gccatctacg ccatattttt
     6181 cggccaattc ttctcctgtc tggcgatctg ggatatctcc gttgatcgtg atcagtgttt
     6241 gcggagcgat ttggtcacgt aaagcaatga ttttagggat gacttcccaa tgtgcatcta
     6301 ctttactcat ctctttacgc gtacgcaaat ggacagaaag attggctata tcttgatgaa
     6361 gtaggtgact gatccattct tccatctcag acatttccgt atagccgata cgcgtcttga
     6421 cgctgacagg caaaccgcca gctttagccg cttcaatcaa ttgtgccgct acttctgggc
     6481 gaaggatcaa gccactgcct tttccacgtt ctgctacatt agggactggg cagcccatgt
     6541 tgatatcgat tccttggaag cccatttctg ccatagcaat gctcatttct ctaaaaaatt
     6601 ctggcttgtc tccccaaata tgggcaacca tcggctgttc atcttctgta aaggtcaatc
     6661 ttcctcgtac actgtctttt ccatctggat gacagaaact gtctgagttt gtaaactcag
     6721 taaagaagac atccggtgct gctgcatgct ttacgacatg gcgaaataca acatctgtta
     6781 catcttccat tggtgctaaa acaaaaaaag gctttggcag ctctttccaa aaattagtag
     6841 tcatttattt gttactctcc attctatcaa gcagtgaagt cgcaatcttt ctcaaaaaca
     6901 ttgtcattat actaggaaac aaaaaaagaa gcaaagtgaa cagcttaaaa gatgtttctg
     6961 attgagcaaa aaaagactgt gacaaaaatc ttatcacaat tccttttccg gaataaatgg
     7021 tgttcaaaag cttgcatctg cggtaataag tccaaccaaa cgaaaaatag gaggagctat
     7081 ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc tctccactaa
     7141 acggtgttca atcagctgac cctcggtatt agctcaacaa acgacaaaat atgaggaact
     7201 attttcccgt ttgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttttct
     7261 aacttctcaa tcctcttcct ttattgatca aataccaagt aacggcgtac aaaacaacga
     7321 tgaatagcac aagtacgatc atcgatgttg ctactggcac atcgattgtt ccaaggaatc
     7381 cgtaacggaa accggagatc atataaacga tcggattgac tttcgaaaca gcttgccaaa
     7441 atggcggcaa catagagatg gcatagaaaa cgccacctag ataagttaac ggctgcaaga
     7501 caaatgtagg cacgatcgat acatcgtcat aagactgagc aaaaatcccg ttgagcagtc
     7561 ctgctaacga aaacaagatt gccgtcatca ataatgtaat gatgaccatg aaccatgaat
     7621 acacatgaag tggtacaaag aacaaggaaa tgatcgttac gagagagccg acgagaatac
     7681 tgcgacccac tccgccaatc acaaagcccc aaatgatcac atgcgtagga acaggcgcta
     7741 ccaagatttc ttcgatgttt ttctggaatt tttgagagaa gaaggacgaa gaaacgttgg
     7801 catacgaact agtgatagca gacatcataa tcaaaccagg cacgatgaat tccatatatg
     7861 aaaaaccacc catgtcaccg atccgaccac cgatcatttt tccgaaaata acaaagtaca
     7921 aggatgtcgt gatcacaggc ggaaccagtg tttggaccca gatacgcaaa tagcggttcg
     7981 tttccttgat agctaaactt tttaatgcag taaaataaag attaaacatt tttctcctcc
     8041 gtatgattat tttcttctgt gattttcaaa aacagttctt ctaaacgatt cgacttattc
     8101 ctcatagaaa gaactttgat tccttgtctt gtcagctgat cgaagattcc gttcacccct
     8161 tgatttcgtt caacttcgac agcgattgtc tgttcatctt caaatgtaca agcgtatcct
     8221 tcaatcacag gtttggtctc atatggcgct aaatcaaaga taaatgtttc aaattgcagt
     8281 ttggatagaa gctctttcat actagtattc tcgatcagtt cacctgattg gatgatcccg
     8341 atgttgcgac aaagcatttc agcttcttct aaataatgcg tcgtcaaaat gatcgttgta
     8401 ccattttcgt tcaattctcg gagaaactcc cacatctcgc gtctcaattc aatatcgact
     8461 cctgctgttg gttcatccaa gatcagcaaa cgtggttcat gcatcaatgc cctagcaatc
     8521 atcagtcttc gcttcattcc cccggaaagc atacgtgcac ggacatttct cttttcccaa
     8581 agattggact gcttcaaata tttttcgctg cgtttcatcg cttctttgcg agagacaccg
     8641 tagtagcctg cttgattcac gacgatttgc tggaccgttt caaagggatt gaaattgaac
     8701 tcttgcggga ctaatccaat ctgttgcttt gctcggacta gatccgtatc cagatcataa
     8761 ccgaagacat tcacttttcc agatgtttta ttgactaaag aagtaatgat tccgatcgtt
     8821 gtagacttcc cagctccatt tggtcctaat agcgcataga aatctccttc tttcacggaa
     8881 agatcgattc ctcgcaatgc ttcgacccca cttccataaa cctttttcaa attatttatt
     8941 tcaagcgcat ttgccattta tttcctatct ccttatagac atgattcttt attgtatcat
     9001 ggaatacagc agatgaaaaa acaacttggt tccagcgaaa aatcaggttg ctgggctcag
     9061 gaaaatctcc taatgaaaga catcaatcgg acgaagtcag acaacctttt cagaaaaaac
     9121 aaatcgaaga taaaggatta ctattcatat gtgcaacaaa aggagcgtga gacaaaagta
     9181 aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaaa agccaagatt
     9241 tttgatccaa taaatacttt cgatcacttc gcctatccca atacatgcca ctgccgcttt
     9301 tcatcaaata acgcggcttc cgtttttgcg gtttctacta aagtctctgg gtaatccaaa
     9361 actttcagca aggcaatcgc atttcgggtc cttgaaggtc cttcttttaa tttgaaatca
     9421 aaactgattc cttttccttc tgttacttgt tcttcaaagt ggacattctc acaataattc
     9481 tttaaaatct ctgtcaattc gatatcatgt gtggcgacaa atgctaaaga tggatactcc
     9541 gcaagccacc gaacgactga agcggaagaa gcaatccgtt cgatcgtatt tgtccctttt
     9601 aaaatctcat ctacgaagca gtagcagcgt tctttggaag ccacttggtc caacaaacgt
     9661 ttgatcgatt tgatttctga aacaaaataa ctgtcgcctt caaataaatc atcttcgatt
     9721 gccatggaag tcaacacatg tccaggttgc agggtaaact gttctgcaat cgctgtttgg
     9781 atcgtctgtg ctagaataca gctgatggct atacttttga catacgtaga ttttcctgat
     9841 gcattggaac ccgtgactaa tgtattcttc tgccagttga ccggattcac taccgcttct
     9901 tttaacaatg gatgatagat atctttcgct gtcacaccgc cctcagtaaa ctctggtcgg
     9961 caagtgatgg gcatataagt acggtaattc aatattgcag cggctacttc taattctccc
    10021 agcaattccc acagcttgat ggcttcagtt gaatgctttt ctaatttagt gagaacgaaa
    10081 tgataggaga taaatggcag catgaacatg atgttgacat attcaaaaat caactctgct
    10141 tcactcccac tcttcatacg aaatgaaaaa cctaatttag ggatgtctct taatggttta
    10201 gtttgctgtt tcagctcttc ttgaagtggt gtcggcagtt ttgctagctg attggcggct
    10261 gaaatcgttg aaaccaaata actcatgcta ttcagctctg tttctagtgt ttgtttcttc
    10321 actagataat agaccgtatt gaatactaac ccaccgattg ccaaatagat tcctagtact
    10381 tgtcctaaaa gaagcaaacc caaacccacc agcggaagca agccaagaaa aataaataaa
    10441 cctacgcgtc caatcttttt actttttcca tccgctagat attgttttgc aaaattatga
    10501 tctttttttc ctaaacgagc gaattgatat tggatttttt ctctcagttg aggattttcc
    10561 tgataaaaag caatcagttt ttctaactgc tgatcttcac caaaatcaaa gctgcgtaaa
    10621 cgttgataca acgcttctga acctacacta gaataggtac tgttgattcc ttcgaatact
    10681 tcgaacatat ccaggtcata ccaagtaaga tcatcgattt cgctatccca tgaacggaac
    10741 ttcttctccg tgagccatgc ttccttcaag ctttcttctt tatcaaatct cggttgataa
    10801 ggaatttttt cccatttgct acgaactgtt tcctttaatt tcaaacgtga aaaaatgtct
    10861 aaagcaacta ataaaataac agctgcaata ataattaaaa cgataaattc tctttgaccc
    10921 atatccctct ccgttccttt atttgttagc tttagtatag cactgttgcg ctatttgaaa
    10981 agagggtaaa aaaacacctt tcaaaataaa aggtgttttt ttcttgtata ttacatattt
    11041 atctctcatt tatcaaaatt gacaaataat catagggagg aattgttgtt aattcttgtt
    11101 tattctccag tgcattgaca actgtcccaa gggaaaggat agcctcaggt actatttttt
    11161 cttgttctgt tggattagct aagcgaagaa caaatccttg ttcatgaaaa taagaaggat
    11221 aaatcgatga tacaattaag tcttcaggta attcaatcaa tgaaaattta cgaggaacat
    11281 caagttcatt ttgtaatggc caaatcttgt tatctaacct gtgaataaat acattcagtt
    11341 tctgcttttg ataagaaata gattgttcta accgtttttc tgcctgtttt gccactttga
    11401 actcattaaa tcttccttct tctacattaa atccaaaagt gactttatac tcacctatct
    11461 cttgagctag cggtgtttcc atcatgacat gcccttcatt tgtcgtatct cctgaagctc
    11521 gcccaggtcg ccaagcaaga ttaggttttc caagttcccc tgttgttgaa aataaggtta
    11581 tgattaattg attttctata cgttcatact cttttaaacc atctgcataa aacgtaaaat
    11641 aatgatcatt ttctgccaca gagacactct tatcgaatat ttctaaatta acaggtttct
    11701 ctaccatagt ttctgaccaa ttcggaggaa tgacatcagg ggtattttca ataaatccgt
    11761 tttgaatttg tgcaattgat ttttcagatt tatctaaaac attaattgct aagcgcatac
    11821 gatgcgagta aacagtatta tgaattttga gtgtgccttc aacgatttga ctttctccca
    11881 gactgaacga tatttcataa gatatttctt ccatttcggg tttttcagat aaacgatctt
    11941 ttaaatcttt aggaagttga gcttttccgt aaacaactaa tgtttcttgt aaagaatctt
    12001 tatatacttt agctgtttct aattttagag atagttctgt atctccttct aatggtgaat
    12061 aatcatacgt atcgccatca tttgctgaat cgatcaaatg aacgaaatca agatattgtc
    12121 tatctccaac tatcaaattc aattgcccat ctttaaaaga aagtttatat ttattgttac
    12181 ttatctcagt tttgtctatc tcgattgctg tttctaattt ttcattattt ttctcaaatt
    12241 caacaacagt gtatcctagt gctggcacat ttacatttat ttttatgtca agttcataat
    12301 aagctggttc atcaaaatat tcgaaacctg tagcaatcat ccgataagca tttttccgtt
    12361 ctggaaaata aacttctttt tcaatgatat tatagggact acctttgaag tgtattttct
    12421 ttgaatcagc tactacatgc acgattttcg atccactata attctcagtc gttgtgttga
    12481 aaacaaggac ttcattcgat tttagcttta atgcatcagc catccgtttt acaataaggt
    12541 tttcgattcc gtcagctatc tcattagctt ctttgattcg atggaaaata tcttccgcaa
    12601 cattatctga aacacagcca ccaatactat catgagcctg gttttgcaaa atctttttcc
    12661 ataaccgacg aagtaggcct ttactgatat ggataccatt tctttctgca atcagcatga
    12721 gcggctcaac tcgttttaga attttttgtt ccaatttaaa attttctatt ttcatttttg
    12781 ttcttactga gccaatagaa cgatgaacac gagagtaaac cggctgacga agttcacctt
    12841 tatattcagg taattctttt ttgtttctga taacttctac ataagaagga taatctgaaa
    12901 taatattgtg gaatttactg tatttattca acttctctac gacttgatca aaatttaaaa
    12961 tcattgactt ttgatctaca cccgaaggta ctaaaatatc tttgtttttt ccttgcatat
    13021 gaagcatttc aactgcttca tccaactttt cttttgcaaa ttcaggaata tctttaattg
    13081 cgtctaaggt catcattcca gtcatataac caaatggaaa attcatggca taaacaaatt
    13141 tatctcccaa tcctttccag ataaaataag gagatggaac catcgtttca aagtttaatc
    13201 ctcgccaaca catgaaatta tcgatttcta cttgatgcaa aagtgtaggc aaattcgcat
    13261 tgaacccaaa cgtgtcaggc aaatacccta ccatcattgg atctccatat ttaaggatcg
    13321 tatcactgat tccaatcatt aagtttctta aaattgattc agcatccact aataaggcat
    13381 ctgtttgtgc ataccacggt cccacgaata gttgtcctgt tttcatcagt cgttggataa
    13441 ccttaagctt ttgcggattg atctccaaat actcatcgac gattgaagtt tgtccatcta
    13501 aacaaaagtt tactttaggg ttcctttcca attcatctag aacttcagta aagacctgat
    13561 cagacaatac gatggcatct tcatttgtaa aataccattc tctgtcccag tgcgtgtgtt
    13621 gaattatatg tgcatttacc atatcagatt ctcctacttt ccttcttcta ctgaatttac
    13681 ttgttgttct tttttatact tgatggattt tagtgcattg accattaacg ctgtaaccac
    13741 tcccccaata acaattgata ctaaatataa aggtatattc gtaacaaaag gaattgccat
    13801 aaaggttgaa agcattgttt cttgagtaac accaaaaaat ccatttagac cacatgctac
    13861 tgcagtgccc accacgatgc ttggtattac tcgtaaagga tctttcacgg caaacgggat
    13921 cgtcccttca gtaatcccca caaggcccat aatcatagct gtctttgcat tatctcgttc
    13981 cgattcatca taaagttttt tgtttaaaat tgttgctaaa aacattccaa atggcggaat
    14041 agcaattcct aataacatgg ctgtactagg tccaaagctt ccgcttgaaa aagaagcaac
    14101 cccaaaagca tatgcgattt tattgatagg tcctcccata tcaaacgcca tcattcctcc
    14161 taaaatagcc gacatcaaag cagcatttgc tcctgacatg ccttctagcc aattagtcag
    14221 tcctgttgtc attgcttgaa taggcgtagc tagtacatac cataatatga ttccaacaac
    14281 taatgtagta acaaaaggaa tcagcataat tgattttaga ctaataactt gcatcggtac
    14341 ttttactttt ttcaatgcat tagctaaata gccacaagct aatccagcaa ccattcctcc
    14401 aataaatccc ataccaagat tttgacacat catcccagtg ataaaagctg gtgctagacc
    14461 gggacggtca gcaattgaat atgcgatata ggctgaaatc atcggtacga taaactgtaa
    14521 tcccgtctga ccaatcattc gcaggactcc ccagaatgta tccgtctggt cccaaacacc
    14581 tgtgccacca aaaatgactg caatagaagt tagtaaccct gctgctacga caagcgggat
    14641 catataggaa accccacttt ggaaatgatt tagaatttct cttccttgtt tcttgaattc
    14701 cattagtaac tcccccacga tatatttttt atttgttaat taatgcaatt gcttcatcaa
    14761 tcgtctcttc accatctttt actacctctg aggtccctac tgttaaaatc ggtttaccgt
    14821 caaagcgacc tcgttctgaa acatttgtat ctactgcaaa tatgacaaca tctgcctcgg
    14881 aaacatccga aattgaaagt ttgttttcta tccccatagc cccctgtgtt tctactttaa
    14941 tatctaaccc tttcttcttc gcaaactttt ctaaattagc ttttgccata taagtatggg
    15001 caatccctgc gatacatgct gttactgcta ctatttttgt catatgaaat tcctcctttt
    15061 aaaatgatag agcttttacc aattcttttt tatttctcga atcttttatt cttttaacaa
    15121 actcgtcatc catcaatctt ccagataatt ctgctaaaat acgtaaatga ttagtacctt
    15181 tatcagtgtc ttttattgct aacaaaaaga cgagatcaac tggttgatca tctaatgcgc
    15241 cccattcaac agaccgcttt aacttggcta cagccactgt tgattcaatt actgctaggc
    15301 ttttgccatg aggaatggcg atatttttcc caattcctgt ggtcatatgg ttttctctgt
    15361 caaatacgtc tttttgaaat tgtttgtggt cagacacaaa cccattagtc tctaacaatt
    15421 tcgataattt ttcgactaca ctttttttat cagatgcatt taaatctatc actatattat
    15481 ttatattgat tttttcactg atcatttata agccttcttt caatatataa actaattttt
    15541 caaacgacga actcgttttt aaatttgcta ataactcatg attcgaagcg atttcattga
    15601 atgtttcata aattttattc aattcaggtt ttactttttc attaagtgca aaaaagaaaa
    15661 cagaatgaac aagtgtccca tcccaatcaa ttccttctgg attaacgtag acacagatta
    15721 ctggcttttt tataaaatct acttcgatat gcggcatagc aaaatcattc atcgctgttg
    15781 aagatagttt ttctcttttg attgctccct ctagtatccc ttctttcgcg taattttctt
    15841 ttaccaattt tttggtaatt atatttaaaa cgttcacttg attatccttt atttggtggg
    15901 taaaaaagca aaatcgttta tctaataaat ttagaaaagc atcttctgtt tgttcattta
    15961 actgtagata ctgttttact tttctgacat ctgcccctaa catcaaagga ctaacaacaa
    16021 taacaggaaa atttgtattt tcaatcggaa tcgtgcttat aacaagttca tcagtgactt
    16081 ttctatcttg tagttcattg atgcttagta catcttctat ctcaaccata tctgcaaaac
    16141 cgttatttat tctttgctct aataattttg atgttccata tccgctacta caaactaata
    16201 tcactttcgt tttgtcaggt ttgtaacgat ccaaaagtga ttgaatatgg agtgttacgt
    16261 aagcgatttc atcttcatta aaatgtatac agaatctctc ttcgatttcc tctaataaat
    16321 ctacacttat cataaatgac cttttaaaag aatatttgat tttgtccgta taagggttat
    16381 agatatttac tcccaatttg agtcttttaa ctgctgcatt gagatgtaat actagattat
    16441 tgatcaattc ttcatcagga taaaattcat ttaatttaat tcttactaac tcttgtagct
    16501 caacacccat atctaaatag gaaagcttcg tttgatctaa gtcgtgattc atagcatttt
    16561 tttcaatcga agtaatgtga atgtcaacat aagcttgttc atctattggc acaataattg
    16621 aaaatgcttt ttcaatcatt ttgattaaaa taagtgtatt ctttgagatt tcttcttcag
    16681 aattattact acgtgataag aaattgcttg tttcaatcct ttctatcgca atagcaaggt
    16741 ggatagctaa agtttgaaat tcataatctg taaatttcaa ttgtgtctta ttcatgtatc
    16801 gattaagcaa ttcggctact tttttcaata tgtccttatt taagaaatta ttcgcttcac
    16861 caatgaaatt gatattcaag tctaagagat ctgttttact gttagatgct gtaaagccac
    16921 cccaataata gttcacaact tctgacatca accttctttt acttttttca tcagctttga
    16981 tgcgcacgcc atttcgatct gaaactaagg acatcccatg cttgtttagt ctttttctaa
    17041 catctttcat tgtgctttct accgtcgacc tgctcacgta taattcgtca gcaagatttt
    17101 gaatctttag agaatcatta gtattcaata atttagcaaa cacataagtt agacggtcct
    17161 ccggagagtc tgcgatattg attttatgac tggataataa atttcgaagt gtttcttttt
    17221 ttccaataag cgaaacgcct tttttaggtt gaaccaacat ttgtacatct ggcatttttt
    17281 ggattatttc tttcaaaatt aaaatatctt tgctaattgt tttcgtagat acatataatt
    17341 gttctgataa ttctttgtaa gttgtgtgct cattttcaat caaaaagtat agtattttca
    17401 tttgccgttc gctaaattcg atgcccatta tcttcacctc ctgaatacag cttaagtgta
    17461 caattattat ctctattttc atacagaaga aagttcttga ttaatgtaga agtttctaat
    17521 attcttgatt atttcaaatc aataaaaaag cctgcaatat ttatatcaca ggcttttttc
    17581 tctattaaat atatataaga taatacattt ttctactagt tctcactaat cttgtataat
    17641 taaaccctcc gcaacttgac ggagatggag aagatgcccc cgtctaatct agcggtcatc
    17701 tctcctccca ttccttccac caattttttt gacaggtaaa gcccgattcc gctagattcc
    17761 gtatttgtgc ggctggtatt ttcggtataa aaacgctgga agactttttc aacagaggtt
    17821 tgcgttcctg gtttgatagg attggccact gttaatcgaa tgaatggatc ctcttttgaa
    17881 aatgtcacct ttgcttgtcc atctgcataa cgcaataaat tctgtatgat attttgcagc
    17941 actcgcagca acatgagcgg atctgctaat acagttgtat ttatcgagtg ttcagcgaac
    18001 gctacctcga tatttttctc agaaaattgt tcataaaaag agaaaaatac ttcttccacc
    18061 tctttagaaa aagaaagcgt atggagatcc atttcttttt gcttcgtctc tattcgagca
    18121 agatcataaa actgatccgt catactgagt aatcttgcaa cagattgttt gatgatcgtt
    18181 aaatacttct cccgtttctc cgtatcctct acctgttcca gtaattgtac ataaccgtta
    18241 atagcagtca aaggagttct gagatcatga gaaaggccga cgatcgatag tctgatgttt
    18301 tcttccattt cttgaaatgc ttgtcctttt tgttcatttt catccaacca tgtattcagt
    18361 gcatctacta ggtccattag attcttttct cgaaattcga ctgaaagacg accaccatat
    18421 tcttgtcgtt cagaaagagt ggcgattttc ttagttaatc tcttgatttc cctttgcagg
    18481 aagaaaataa aacttcccat aaagataaca acgagaagca acagccattt aatcaaatct
    18541 aaaccccact ccccacaccg tatgaatata cacagcatgt gcctttgcta gcttccctcg
    18601 aagattggaa atatgcatat tcactgtttt ctcactatca aaatatggtt cttgccaaac
    18661 tgtttcataa agatttgctc gcgaaaatac ttttttcgga tgttctaaaa aaagcttcag
    18721 cagatcgaat tctcttcctg tcaaatggac agccacacca ttcacattta catccctcga
    18781 ctctttgtcc agtaagattt ccttgtaata gatgcgttgc gacagatctt ttacttggac
    18841 agaagtctga tgacgaagtt ggatgccgat tcgtaacaaa agttcttcga tatcaaatgg
    18901 tttcgtcaca tagtcatccg ctcctgctgc caacaaggaa actttatctc tttgatcgct
    18961 ttttgctgaa agaacgatga tcggaacatt cgatgtctgt cggatttctg ctaacaatgc
    19021 ttcacctgaa agccctggaa gcatgagatc tagaaggatc aaatcgacag gatatgtgct
    19081 taacaataat tttccttccg tacctgaata agcatcaaga agtttgtatc tctgttcaag
    19141 aacctcctcc agtaaggaat gaacagcttc atcgtcttcg ataatcaaaa tagtttccag
    19201 caggaccacc tacttaatgt cagatttttg gaaaataaac attcctagag ctgatgatac
    19261 cacgattgtt actagactga ccagaatcat tttcggtgct tgcgaataag ttgcttgttg
    19321 cgcaaagtcc gtatacatga gccacgtttc cgtaaaccac tccgttagaa attccaagcc
    19381 tttgattttt gcgaaaacac cgggaatgaa ggccgttccc atgatataaa gaaaagaaag
    19441 aagcaaactg acactggtac ttctagtgat gaatgtcaaa gccactggaa cagataatgt
    19501 ccctaatgtc agcagaagca atacaggaaa tacttttaga acataatttc catagttttt
    19561 gattccctca acttcaccaa atccgaaagc aagtgtgtaa gcaagcatgg ctagtcccgt
    19621 gatcaaaacc acgccaagtg ttgtgatcaa aagcgtaacg agaagtttcg acacataata
    19681 agtcattcga ttccgtccta aagataacgt attgcgaatc gtaccgtttt gaaattcttc
    19741 cccaatataa aagcacgcaa atgctgcgaa agccagaaga atccatgcag ccattttttc
    19801 taccattaaa atccctgttg caccgttgat gactgtatcc gttgcttggt ttaattcatt
    19861 gccgtatttt gtatgcatat accattcgtt ccaagaataa aaaagcggaa gtacgaccat
    19921 cagtcctagt gagacccaca ttttacggct cttccatact tttatttttt cagcagttaa
    19981 tagattaaac atgtggattg cctccagtta attgtaagaa ataatcttcc agtttttgcc
    20041 caactaggtg aataccatcc acaggaactt ttgcttctac caatgcttga ttgatggctg
    20101 ctacttggtc aattccttca aaaagctgga taacacggct agattgtaca aaataatccc
    20161 tataaccaag agagtcgaga accgttactg cttgttccgt cgccgaagtg tcaattttta
    20221 taaattgacg agattcttgt gccaattctt ctttcgataa ttctttgatc aagtgtcctt
    20281 catgcaaaat accatagtga gtggcgatct gtgacaattc atctagcaag tggctagaaa
    20341 gcaagacggt gatgccccgt tcttttacca aacgttggat gatttctcgc atttctgcca
    20401 tccctgctgg atccatccca ttcgtcggtt catccaaaat caaaaattct ggattcgtga
    20461 tcagtgcatt tgcaatagct aaacgctggc gcatacctaa agagaaattc tttgctttct
    20521 ttttccctgt attttccaat cgcatcattt tcagcaggtc ttcgatttct ctatccgaca
    20581 caccgccgtt cgctgcttgg atacgtaggt tatctcttgc agttaattct ggataaagag
    20641 caggggtttc aatcgattga cccatacgtc gtcttgctgc ctgcaaatcc gtcgttccaa
    20701 ataattcgat cgaaccttca tcaatcgaga tcaaacccat aatagttctc ataaaggtag
    20761 acttacccgc tccattttcc ccaatcaatc catagatcat tccacgtttg atttcgattg
    20821 atactttatc taatgctttg gcagcaccgt attttttggt tataccagtt gctttcaaga
    20881 ccgtttcatt tccaaaatcc atacttatcc ttctttctta ttgatgagtg aagtatagtt
    20941 gacgggtata aagaaagcag ccagaaatgt ataaagaaag tgtaaatttt ccaattgaat
    21001 gtcaaaaaaa acaatcggac aatacgtgtc tttcctatta tcaggcagtt tgttatacgc
    21061 ttgtatcagt ttcctgattc tttcttttcg accaaagtcg tttctctgta ttcctcttca
    21121 ctgaaaattt ttgcttcttt cagatcaagc ttgagtaatt ttaccagacc ggttataagg
    21181 ataactatag caagactccc tcccagaaaa attagactgt ctcgcagacg tggttgcgtt
    21241 gtcttccaat caaagagcgc accaaacagt gctaatccaa gtggactggc caccatggta
    21301 atcgttgtta tcgttgacat aagtcgtcct tgtatatgcg ttggaacttc tcgctgaagc
    21361 cagaccatat aaaaagcaaa agaaaacatt aatccttaaa aacggactta tgaaaaataa
    21421 tacatgccgt ttgggattta caattagcta ccaaataaga ggttatgaca aaagactttt
    21481 cacaatccct tcttccgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
    21541 atatttatca aacatgagaa gcaatttttg taaattcctt cttatttctt gaagctgacc
    21601 acttctgtca caacctcaga agcggataaa taatattgtt tgatgatact ttatcttttt
    21661 cccgtttgtt tatagatcga atgatattat agaccaagaa tcctacctat taacatagct
    21721 aaaaacacaa aaaaggcact ttccaaattg tggaaagtgc cagaaaagtt aggattaagg
    21781 taactgcgct cagcattgct tcgcccagta cgattctcgt aactcgtgaa ctcgaacgat
    21841 aatcgcaatt aacgttttga gaactgtgaa gctttacggg ctttcttaag acctggtttt
    21901 ttcttcgtat cattgaataa gtttgaaaaa ccttgattta taaaggtttt cccgtaaata
    21961 tattttatta tatttgatta aatttgaaat gtttgtgttc taaaatgtgt tctaatttaa
    22021 aggcagtata tttcgtattt tagattaaat ttttaggctc attcattctc aaatccattc
    22081 tattcagtca ataaaaattt taaaaagact ttataaacaa agatgttcaa gcgagcatct
    22141 tatttttttg tgcttaattt gaaaggagaa catttcatgt ataaaaaaca aaaaaagaaa
    22201 ttatgtgtat taactatttt gagtttggct gttcaagcaa ttgttggagc aattgctcct
    22261 acgattactt ttgctgatga aattacccat ccacaaacgg taaccgtaga actagattta
    22321 gcacatcaat atgctgttga aggaactttt agtgatggtc gtccaatgtc agaagtcact
    22381 gttccgcatt atgcagtgta caacggcttt aaacaagata ttttctgtat tgaaccagga
    22441 gtcccgattt acaatgagtt cactcctggc tatgagaaaa acccgttacc agatatgtcc
    22501 gataaagcca aattagtttc cgttttatgg aaaaaagtag gtacagatgc agatactcat
    22561 attgtggcac agaagatgat ctggcaagaa gttaatgggt atacccttca ctcaataaaa
    22621 cgatcagatg gtagtgccgt aaatatcgca gccattgagg caaaaataaa tcaagccatt
    22681 gacgattatc agaagaaacc aaccttccat aatagtacgg ctaaaacagt attagggcaa
    22741 tcgactactg tgacggatac gaataatctg aatttgtcag agttcgatga ggttgtggaa
    22801 aatgccgcaa acattgatta tcgtgtgaat ggtaatcagt tgataatcac cccaaatgcc
    22861 aattcaaaag aaagtggtgt gctgacgctt aagaaatctg ctggtaccgg aacacctgtc
    22921 gcctataaaa aggctggcca acagacttta atggccgggg cgattgataa acctaatacc
    22981 tacacaatca aaattgatgt ggaaacggag ggttctttaa agatcaaaaa agtcgataaa
    23041 gaatcgggtg atgttgtacc aggaacggtt ttccatttag actttggaaa aactttacct
    23101 gcaaaagacg tgactactga caaagaaggc attgctacat tggatgagat tcctcatggt
    23161 acaaaagtaa ccattaccga aaaatcagta ccggcgcctt atacgattga taccaccccc
    23221 atgactacca ccattaaagc aggcgaaacc atttacgtga cttcaaaaaa cgcacgggaa
    23281 aaagggcaaa tcattctgga taaaagcgga gttgaaacag ggagtgatct ttggaatgac
    23341 aattattcct tagctggtaa tacgtttgcc attcgcaaag acagtccaac cggtgaaatc
    23401 gttcaagaaa tgaccacgga tgaaaacggt catgcggaaa caccaaaaga gattgctaat
    23461 gcgttggaat tgggaaccta ttatgtgacc gaaactaaag ctagtcatgg gttcgtgaat
    23521 acgttcaaac ctgtaaaagt cgaattgaag tatgccaatc aaaccgtagc ccctgttacc
    23581 agtaacgtaa aagggcaaaa tcaagaagtc actggcgaaa ccactttgac gaaagaagac
    23641 aaagatactg gggataaagc acaaggtaag gcagtctttg agggtgctga atacaccttg
    23701 tttactgcta aggatggaaa agctgttaaa tggagtgagg cttttaaacc agagttagcg
    23761 aagggaacga aaggttctga tgaaacggtc actttgactt tagacgaaaa gaaccaagtt
    23821 gccgttaaac atttagctat caacgagtat tattggcaag aaacaaaagc gcccgaagga
    23881 tatagccttg atgaaacaaa gtatcctgta tccatcaaaa aggtggatga tagcgaaaaa
    23941 aatgccgtga ttacccgaaa tgttacggca aaagaacaag tgattcgctt tggctttgat
    24001 ttctttaaat ttgctggatc agctgcgggc actaccgaaa ctggcttcaa tgatctgacc
    24061 tttaaagtgt cgccattgga agggaccaat gaaatcacag gtgccgaaga tgaagcgacc
    24121 acagcttata acgagcaatt agggtttgat ggttatggca agtttgaaaa tcttccttat
    24181 ggggattatt tacttgaaga agtagaagcc ccagaaggtt ttcaaaagat tacgccatta
    24241 gaaatccgtt ctacttttaa ggaaaacaaa gaagactttg tgaagagtga gtatgtcttt
    24301 accattaccg aacaagacca aaaacaacca attaaaacgg tgaccgttcc ttacgagaag
    24361 ctgacgaaca aagcattttc tgttagtttg aaccgtttaa tgctctatga tttgcctgag
    24421 gaagaagata gtttaacttc tcttgcgact tggaaagacg gaaacaaaga attaacttct
    24481 ctggattcta ccgagctagt tgataaattg agttacaatc tacatgaaat caaagaagac
    24541 tggtatgtgg tagcgcaagc cattgatgtg gatgcgacaa aagctgccca agaaaaagat
    24601 gaaaaagcca aaccagtggt gattgcagaa acaagcgcaa cgttggcgaa caaagagaaa
    24661 acaggaactt ggaaaattca gcataaatta accgccgaac aagttttaaa taaaactatt
    24721 gtcttattca actatgtgta tgaaaataag gaagcttttg aagcaggcga taagccagta
    24781 gcgaaggatg ttagcttgaa taaccaagcc caaactgtca gttgtacagt ggaacaccat
    24841 gtttctatcc aaacaaaggc ccacctagaa aacggttctc agacctttac tcatggtgat
    24901 gtggtggata tgtttgatga tgtgtcgatt actcatgatg tactggatgg ctcaaaagaa
    24961 gctttcgaaa caattctgta tgctttatta ccggatggta caaacaaaga aatttggaaa
    25021 tctggcaaga ttgattatga agtaaatgat aaagaattca ccaaaactgt gcttgcgaaa
    25081 aaagtagata ccggaaaata tccagaagga accaagttta cttttgcgga aatcaattac
    25141 gataaagatg ggaatatcaa tggaaaacac aatgaagatt tgaaagaaaa atctcaaacc
    25201 ttaacaccaa aagaagttcc aaccatacta agtacgccga aacaaccgga aacaccaact
    25261 gttccaagtg gctctcaaga atctagtccc acagtgaaga ccttccctca aaccggggag
    25321 aaaaattcca atgttttact gttcattggt tttactttga tttttgcgac ggcgggctat
    25381 tatttctgga atcgccggaa ctaaggtgat gagatgatac aagtaaatcc taagaaccaa
    25441 cgtgcgcgac cgcctcctaa aaaagtagtc gcgctatttt tgtatccaaa actaacaatg
    25501 aaaagaggaa aagaagatgg aattgaaatt tgtcgtgcca gatatggctg aaacctttgg
    25561 aaagttaagt tatgccggtg aaggagaaat tataacagaa ggatatggac ggaatactac
    25621 ggtgattggt cgcagttatc atttgtattc cagtaagcaa cgggccgatg atattgaggt
    25681 ggtagtagct gcggaagccg gtgaaaagga ttttgatcaa gaccaaccgc taaaagccgt
    25741 gaatccccat ttggttgcca aaggctatga gattgagaat cgtgggttta ctgattacgt
    25801 gttgtatgtt gatgatttag tgaaagcata ggaggaaaag aagatgagat taacagaagg
    25861 tattgtcgta gattcaggtt taacatttgg gaagttgcgt ttttccgcat tacgccgaga
    25921 agtacggaag caaaatgagg atggaacaat tggtaatgag gtaaaagaac gaacctataa
    25981 tttaaaatcc tctgcacaag ggcgaatgat tcaagttagt atcccagcta atgtaccctt
    26041 acgcgagttt gcttatgatg cagaggtaga gttggtcaat ccaatcgtgg ataccgttgc
    26101 caattatgtt tttcgagaag gaactaccgt taattggttc attaaggcgg atgatttagt
    26161 cttgaagcgg cagccgaatc aaggaaatcc tacgaaccaa aatgaaagaa agaaataggt
    26221 gaagattatg gaaattaatg ttgaacatat tttagattgt ctcgatcaat atggaaaagg
    26281 cgagctgact gaggaacaac tcgttaaagc attaacctct gatgaaaaaa tgtttctgat
    26341 tatacatcaa ggtttacttg gagaaaatag cgacagtgaa gaagactctg atgtactaga
    26401 ctggttagga gaagaagagt ctttctttat agttgtcgaa gtaaatgaaa acttatgtcg
    26461 gcaggcagaa tccattttgg aagaaattgg tgtggagatg ccggatgcta ttgaaggctt
    26521 tttaaatcaa ttggttgaaa cgaaacaact cccctcctcg tagcagtaaa tgactagcat
    26581 aactttttga aattgcctaa tgaaatccta ttgggctttt tcgattggag gtggaaacca
    26641 tcaaaatgta caaaggacat cgcatacgcg caggagatca gcacttggtt tatcactttg
    26701 ttcttggctg gctactcgct ctgttcatcg gttggatgag cgtcttttat tttcaagagt
    26761 ttagacaatt tgatatttct aagctatcac tttctactat tgaaatcgtt tggtctataa
    26821 aagatttagt atgtctgctt ggaagtctcg ctttttcagg agctatgata ttgctttata
    26881 ttcacttttt tcttgatcat tggcgaagct tgtggcatcg acaaaagcta gctcggatga
    26941 ttctagagaa ccattggtat gaagtgaaac aaactcaaag tgaaggcttt ttcaaagatt
    27001 tgaatagtag ccgaaccaga gagactatca gttacttccc caaaatctgt tatcgaatga
    27061 aagatggatt actgtctatt cgcgttcaaa tttcacttgg gaaataccaa gatcagcttt
    27121 taaaattgga aaagaagtta gaaagcggac tgtattgtga gttagtagaa aaggaactca
    27181 aagactccta tgtggagtat actttactgt atgatatgat cgccaatcga attgggatag
    27241 acgaagtagt ggcagaaaat gggactctgc gattgatgaa aaatcaagta tgggcttatg
    27301 attctttacc ccatatgtta atcgctggtg gcacgggtgg agggaagacc tatttcctcc
    27361 tcaccattat cgaagcacta ttgaagtcag atgcagaatt gtttatcctc gatcccaaaa
    27421 atgcagattt agctgattta ggtacggtga tgcctcatgt ttattcacaa aaggaagaaa
    27481 tttctgcttg tgtggaagat ttctatgaac gtatgatggc tcgtagcaag gcaatgaaag
    27541 aaatgtctaa ctacaaaaca ggagagaatt atgcctatct tggacttcca cccaactttt
    27601 taatctttga tgaatacgtg gcttatatgg agatgttaac gacgaaagaa agtgcggtga
    27661 ttttgaataa gctcaaacaa atcgtgatgt tgggtcgtca atctggtttc tttctgattt
    27721 tggcttgcca aaggccggat gcgaaatatt taggagacgg aatccgcgat caattcaact
    27781 ttcgcgtggc tttgggtcgt atgagtgaac tcggatattc catgatgttt ggggaggtcg
    27841 aaaaaaactt ctttatgaag cacatcaaag gtcgaggtta tgtggataca ggtggcagtg
    27901 tgattagtga gttttatacg ccacttgtac caaaagggta tgatttctta gattcaatta
    27961 gtaaattaga aaagatgaat gattgagtga tcttcaatac tgactttata cttcaagtaa
    28021 cgtataatac ttttatatag taggaagaaa ggggataatt aatatggaaa gtaatgattc
    28081 ttatttagag tatgcaaaag caaataagga taagtttatt tcttatatta tcaaagggaa
    28141 atcccccgaa gttggacgag acgcagtttt tatggcaggg agtcctgggg ctggaaaatc
    28201 agaggttgcc attggattag ctgagaatta tgataaccat gtgattattg atgcggatta
    28261 ctttcgcacc cagtttcctg attataatgg aaaaaactct agtctctttc aaaaagcatc
    28321 ttcttggttg gtagagcagg catttagata tgtcttagat catggctatt cttttattct
    28381 ggatgcaact tttgcaatat taagtgctga aaaaaatatc tcgcgggcgt tgaaaaaaca
    28441 ttttcgagtg acgattttct atgtttatca agaccctaaa atcgcttgga aatttacaca
    28501 agaacgtgaa attgcagagg gacgtcatgt gccgaaaaag gcatttatta acgctttttt
    28561 caaatcaaga gagaacattg caaaagtaaa gagtaaacat ccagatgtat tgcttcatat
    28621 cataataaaa gattatacga ataatatttc cgaagttcat tatgctacgg ataatctaga
    28681 attattttta ccactagggt atagtaggaa agatttggag gttcaattac atgactgaga
    28741 aagaacaagt aacgaaaatt gtaaagaaat acaataagag cattgcggat ttatcggaaa
    28801 atgctactgc aaaagagttc aaaacggtga ttaaatatgt agccgatcag gccaatgaaa
    28861 aacaacggaa attagttgga ttaaataaaa aatagtagga caaattaata atgtatgagc
    28921 caagagcaaa atgttcttgg cttttttctt tgcaatgaat gaggtaatgt atgagatttt
    28981 tagatttatt cgccggtatt ggtggctttc gtttaggtat ggaacaggcg agccatcatt
    29041 gtatcggttt ttgtgaaatt gataaatttg ctagacgtag ttataaagca attcatgata
    29101 caagtaagga ggtggaaatg catgacatca caagtgtatc agatgagttt attcaatccc
    29161 tcggaccagt ggacatcctt tgcggcggat ttccgtgcca agctttttca attgcgggaa
    29221 agcggcaaag attttccgat actcgaggta ctttattctt tgaaatcgct cggttcacca
    29281 ctcttctccg acctaagctt ttattccttg agaacgtccg aggattgctc aatcacgaag
    29341 gaggggctac gttcgagacg atcctccgaa cgctggatgg attggggtat gacgtggagt
    29401 ggtaggtgct taactcaaag gcctacattc cccaaagccg ggagcggata ttccttatcg
    29461 gacattctcg agacgcatgt accgaacaag tatttcctat cattggaccg tcttcaacat
    29521 ctgatcaaaa catcagaaat ttggtaaata tcaatccttc caatcgagga atgggtggac
    29581 aagtctatgg ttcagatggc gtagcgccaa ccttaacagg tgatgaagga atcaaaatcg
    29641 cactgccagc aagggatgga atctctgtag caggactatt ac
//
LOCUS       DADVXK010000024        29330 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.024, whole genome shotgun sequence.
ACCESSION   DADVXK010000024 DADVXK010000000
VERSION     DADVXK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.024"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            2..697
                     /locus_tag="KB909_000997"
     CDS             2..697
                     /locus_tag="KB909_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6837048.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(1139..1936)
                     /locus_tag="KB909_000998"
     CDS             complement(1139..1936)
                     /locus_tag="KB909_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBB6837049.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(1933..3117)
                     /locus_tag="KB909_000999"
     CDS             complement(1933..3117)
                     /locus_tag="KB909_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6837050.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(3142..4389)
                     /locus_tag="KB909_001000"
     CDS             complement(3142..4389)
                     /locus_tag="KB909_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6837051.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            4604..6349
                     /gene="dnaX"
                     /locus_tag="KB909_001001"
     CDS             4604..6349
                     /gene="dnaX"
                     /locus_tag="KB909_001001"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBB6837052.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            6369..6683
                     /locus_tag="KB909_001002"
     CDS             6369..6683
                     /locus_tag="KB909_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBB6837053.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            6708..7304
                     /gene="recR"
                     /locus_tag="KB909_001003"
     CDS             6708..7304
                     /gene="recR"
                     /locus_tag="KB909_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBB6837054.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            7368..8012
                     /locus_tag="KB909_001004"
     CDS             7368..8012
                     /locus_tag="KB909_001004"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBB6837055.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            8027..8356
                     /locus_tag="KB909_001005"
     CDS             8027..8356
                     /locus_tag="KB909_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBB6837056.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            8370..9308
                     /gene="holB"
                     /locus_tag="KB909_001006"
     CDS             8370..9308
                     /gene="holB"
                     /locus_tag="KB909_001006"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBB6837057.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            9344..10168
                     /locus_tag="KB909_001007"
     CDS             9344..10168
                     /locus_tag="KB909_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBB6837058.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            10161..10508
                     /locus_tag="KB909_001008"
     CDS             10161..10508
                     /locus_tag="KB909_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBB6837059.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            10577..11449
                     /gene="rsmI"
                     /locus_tag="KB909_001009"
     CDS             10577..11449
                     /gene="rsmI"
                     /locus_tag="KB909_001009"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBB6837060.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            11558..12679
                     /gene="dinB"
                     /locus_tag="KB909_001010"
     CDS             11558..12679
                     /gene="dinB"
                     /locus_tag="KB909_001010"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBB6837061.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(12733..13335)
                     /gene="nrdG"
                     /locus_tag="KB909_001011"
     CDS             complement(12733..13335)
                     /gene="nrdG"
                     /locus_tag="KB909_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBB6837062.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(13650..15839)
                     /gene="nrdD"
                     /locus_tag="KB909_001012"
     CDS             complement(13650..15839)
                     /gene="nrdD"
                     /locus_tag="KB909_001012"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBB6837063.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            16138..16932
                     /locus_tag="KB909_001013"
     CDS             16138..16932
                     /locus_tag="KB909_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837064.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            16922..18964
                     /locus_tag="KB909_001014"
     CDS             16922..18964
                     /locus_tag="KB909_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837065.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            19245..19394
                     /locus_tag="KB909_001015"
     CDS             19245..19394
                     /locus_tag="KB909_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBB6837066.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            19405..20919
                     /gene="dltA"
                     /locus_tag="KB909_001016"
     CDS             19405..20919
                     /gene="dltA"
                     /locus_tag="KB909_001016"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBB6837067.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            20916..22121
                     /gene="dltB"
                     /locus_tag="KB909_001017"
     CDS             20916..22121
                     /gene="dltB"
                     /locus_tag="KB909_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBB6837068.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            22166..22399
                     /gene="dltC"
                     /locus_tag="KB909_001018"
     CDS             22166..22399
                     /gene="dltC"
                     /locus_tag="KB909_001018"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBB6837069.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            22402..23670
                     /gene="dltD"
                     /locus_tag="KB909_001019"
     CDS             22402..23670
                     /gene="dltD"
                     /locus_tag="KB909_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBB6837070.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            23811..24893
                     /locus_tag="KB909_001020"
     CDS             23811..24893
                     /locus_tag="KB909_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBB6837071.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            24893..25696
                     /locus_tag="KB909_001021"
     CDS             24893..25696
                     /locus_tag="KB909_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6837072.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            25766..26506
                     /locus_tag="KB909_001022"
     CDS             25766..26506
                     /locus_tag="KB909_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6837073.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            26517..27521
                     /locus_tag="KB909_001023"
     CDS             26517..27521
                     /locus_tag="KB909_001023"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBB6837074.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(27566..29263)
                     /locus_tag="KB909_001024"
     CDS             complement(27566..29263)
                     /locus_tag="KB909_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837075.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         9261 a         5171 c         6045 g         8853 t
ORIGIN      
        1 tatgatcttt ttagatgaaa gtttggatgg gggagcatca ttggatagta gagtcttaaa
       61 ggaatatttg gataaaaatg attttccgat tatacgcaaa ggatatcata aatatttgac
      121 attcgaaggg atggaagatt cccatacgta tatcttgaaa gagggaacgg taaaagcaag
      181 tgttatttca aatgatggga gagaatttaa ccttcgctat atcaaagatc ttgaaatcgt
      241 ctctctttta aaagacgaat attcacaatt catcgattcg ccgtataata ttcgagttga
      301 atcagaatat gcagagtttt atcgaatcaa tcgtgtgcgc ttttggcaaa atatcaacca
      361 agacccaaag ctacaacact atgtaaaaga gtattaccgc tatcgtctgc tttattcgat
      421 gaaaaaaatg cagcaaatgc tattaaacgg aaagctggga gctgtttgta cgcaacttta
      481 cgaattatat gatttattcg gtgtgcggac agaagaaggg atgctgatcg atttttcgat
      541 cacgaatgaa gaaatcgcca aattttgtgg catctcaact gctagcagtg taaacagaat
      601 tttaaaacaa ctgaaaaaag atggtattat caccgttaaa gaccatcata tcgttatttt
      661 gaatatggac ttgttagaag acaatattat cttttgatga acaaagaggt tgtgaaatca
      721 gcgttttgac ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
      781 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt taccaagagg ttgtgagcct
      841 gccgtttaac tctgagtcac aaggaacaat ttcaaaaaac agcttttcat gtttgatgaa
      901 tattgtgact tgtgaccgag gagttggtag gagaacaccg tttaccaaga ggttgtgaaa
      961 aagctgttct gcatcaagta ataagaagag ccaagtaaaa acagtctctt atgtttttaa
     1021 cttggctgga cttatcaccg tagatgtaag cttttgaacg ccgtttattt gcaacaaaag
     1081 gggctgtgac acgatttttg tcacagccct ttttttgcga acattcattt agcaattttt
     1141 agaaacttct gccgccaccg ccaaaagtcc cgccaccgct agaatgggta gtacttccgc
     1201 caccgccgct tccaggaggt gggcttttgg ggattcttct tgtcgtgaca aaagaatttg
     1261 tcagacgatc ggttttttca gttaatttga tactggattt ttctcggaat ggatatttgt
     1321 agatgcctga tttcaattga taacgcgaaa cagtcacaaa ataaaagaca agactaagga
     1381 taagagccaa aacaacagca atgatgattt ctactgtcgt caaaacctta tagcgtgtaa
     1441 ttttgccagt ttcttcgtct acacgataat gtcctcctgg aactccgtct tccacatatg
     1501 ttgctgattt agacaggtaa gcttttgcag cattgtaata ggcagcattt gtcatctgat
     1561 cataaacatc atctaagatc gaatcgattc tgctatcagt caaataatcg atcatattac
     1621 cagaagtcga aatgtagatt tcacgctgtc ccatatctaa tagcaatact gagccatttt
     1681 gatcatttcc gactgcgtct cttaagtaat tatcagcaaa gtctcttggt tcttctgaat
     1741 tagatgtagt cgttacgatc aagactcgtc ctttgatttt ttcattcagc ttttctgcct
     1801 gttgttccaa agattggatt tgatctgttg tgaataaccc agcctcatca tttaccgtag
     1861 ctgtatctgc atgagtagcc accggccagc caacacttac tagcaaaaga aagaataaaa
     1921 aaaatttttt catcatatca agtaacctcc gatcagaaag aggatcgcta gcccagcgaa
     1981 aatcccaaga gcggtcagtc ccaatttttt ctggctgatc ggcaggacac cgctgacctt
     2041 tcctgtttgt ccattcattg cgtagtagta gactttttta cttgagtcat tgcttcgata
     2101 agtaacaagc cataccggca gtaatacgta attatttact tcgtttgtga ttgaagcaga
     2161 agttcgcaca ccggtcaatg ttgtatatcc atttgcggta tcttttaaca gcttctctga
     2221 atagtctttt aattcagatt gaatctgtga tttgattgcc tcatattcga tatctctttt
     2281 ttctgcttgg aacccggcta aatactggct tttaaaatca attgctttat ctaacgggaa
     2341 aggttgcacg ccttcgacca tcttttgttg cgtatttttt gataaggcat tttttactag
     2401 ttctttaaaa gaaagcttgc ctgctcttga aacagcaaat tgcttcgttt ctgtgtattc
     2461 gatgtcacct atccgccata tgcggataac tgtaccattc gcctgcatgg caccatctac
     2521 ttcagcatct gtagcccaat aagggaaata cacacctgtc aacttatcga tttgatcctt
     2581 attgaaaaaa gctttgggaa caaaccattt tttcttggtc caagcgagaa atctgttgat
     2641 tgcttcttct ttctcgacag caaaaggaag tactttattt ggcaagaatt ctccgcttaa
     2701 acgtcccgat agtacgacgg gattatggca gtagtaacaa taagtcgcag cagttgtcgc
     2761 atcagtcacg atctctgcac cacagttggg acaaagaaaa agatctatcg ctgcggtatt
     2821 atctgcagat tcgtccgctg tatctgaaaa accgcctgcc tcgtcaaccg ctttgcgctc
     2881 ggcttcattc atatcggcaa gctgttcttg ggctgtaaaa gtaaaatctt cggtaggtga
     2941 aggttcttct ttgctttctt cgccagccat acgcgcttct ttttgctttt gctcatattg
     3001 gctgacttct tcttctgtat agatattcag gcagtattcg caatgaaatt tttggtcttt
     3061 gggatcaaaa gtcaacggac cgccgcaatt aggacattta tgtgtaagaa catccatcag
     3121 ctgcacacct ttctaaataa attaattaac ggggattcct ttaaacggtt taccacagtt
     3181 tggacagaat ttagggatgc cgttggaaag atccacgatc tcattgcatt cactgcatcg
     3241 catttgtagc ttaggctgaa cgttttctac aggtttggca gctccgcagt tggaacagaa
     3301 ttttccggaa ttttctgtcc cgcaaactgg acatgtccaa gtatccgcat ttccttgtgc
     3361 agtttgttga ttttgttttt ctgcttgttg tttgatttgt tcttggttat tttgagctgc
     3421 ttgagaaaga taagaaccat ttgcattcat tcccatacct acacccataa agccggtcat
     3481 tgctcctgct tcattttttc cggctgcttc cataccacgt gcaatggaac cttgcacgta
     3541 gccttcacgt acgctaggat cacctagcat cgccccttcg ttacgcatat tgatcagttt
     3601 cacagaatca tcggtgtaag aaatgctggc tacagccaca gaaacaatct ccatcccacg
     3661 taattcacgc caagaatcat ccaatgcagt atccatgtat ttgcttaatt ccaaactctt
     3721 agatggtaca taagaaatcc gttgaccatc tgcagacatc tgattgattg ctgattgtag
     3781 cgctgttagg aattcagcta aatactgctc attgatatca ttgatttcca cttgtgtttt
     3841 gtttttaggg attgcgtttg tataaaataa aatcgggtca acgacatgaa tagaataagt
     3901 gccatgtgcc cgtaagaata attctgcgtt atagaaattg tcaaagtagt tcaacggcgc
     3961 gcttgtaccg aatttgattc cctttatttc ttggagattg atataaaaaa cttgttgttt
     4021 ctgcggtgtg acgccgccaa atttgaatcg gtcaaaagtt tcagcaattg cttctttcag
     4081 tgttccattg aacatggaag gagctgcgtc atttttaatg gtgtaataac cttcctcagc
     4141 ggtataatcg atgatttttc caccatcgac caaaagcatc atcatgtttg gatagacatg
     4201 gacgactgtt ccgtctgtta aaacatcttc tgttccttta cgattggagc cacgtttgtc
     4261 atctttgcgg actttgacac cttttgtcat gaccgttgta tcactcatat tgtctggttc
     4321 gatgacttct agccattgat ctgccagacc gccgccaacc atacttgttg ctgctttgat
     4381 aagacccata aaaaattcct cctctgattc agctagtgcc aaacaattat tgtttattta
     4441 ttataccata ggaagatgtg aaacttctcg gactagagac ggaattgaaa tggaaaattg
     4501 cgtattgttt aaatacctga aaaagccgag aaggatagta gtttttttac ctaatatcac
     4561 gtataataag agatagtgaa ttttttaaaa aagggggatc cttatggcat atcaagcact
     4621 ttatcgagtc tggcgttcgc agcgtttcga agacatcgtt ggacaaaaag ctgtgacaca
     4681 gacactaaaa aatgctattg tttcccacaa aacctcacat gcctacttgt ttacaggacc
     4741 cagaggaacc ggaaagacga gtgcagcaaa gattttcgca aaagcaatca actgtccgaa
     4801 cagtaaagac ggtgagccat gcaacgaatg cgaaatgtgt cgatcaatta ctgctggtac
     4861 gcaagaagat gtgatcgaaa tcgatgctgc cagcaataac ggagtcgaag aaatccgatt
     4921 tatccgtgat cgggcaaatt atgcgcctac aaaggcagcg tacaaagtgt acattattga
     4981 tgaggtacat atgctttcaa caggagcttt caatgccttg ttgaaaacat tggaagagcc
     5041 aaaagaaagt gtcatattca tcttagcaac gaccgaacct cacaaaatac cagctacgat
     5101 catttcacgg actcagcgat ttgattttaa acggatcaat acggcagata ttgtcgaaca
     5161 tcttgaattt atcttgaaag aatcgactat cagctatgaa ccagctgcat tgaatgtgat
     5221 tgcccgttct gcagaaggcg ggatgcggga tgcattgagt attcttgatc aggcaatctc
     5281 gtttagtgaa ggaacaatta ctttagatga tgccatgcaa gtgacaggta gcttaactga
     5341 cgaaatgatg gacagttact tgagtgcttg cgtgaaaaaa gaagtaccag aagcattgga
     5401 aacattgaac caaattctcg cagccggcaa agaatcacgt cgctttctag aggatatgtt
     5461 acaatactgc cgtgacttgc tgatgtatca gcaagcacct aacctagttg aggaacaatc
     5521 gagtacgatc agaagtacat ttacagaatt ggcacaaact gtttcagcgg atcagctgtt
     5581 ttcaatgata aagattttga gcgatactca aaatgaaatt cgttttacca atagtgccgc
     5641 tatttatttg gaagtcgcta cagtcaaact tgcacagcta ccgtctgctt ctgttccttc
     5701 agcagatgta gcatttgcag atgatcagat agtaaaacag ctacaacaag agattaagga
     5761 actaagaaac gaaatcaagg aactacgcag taatacagga attgagaata caaaagtaca
     5821 gccggtacag caaacaaatc ataaaaaaca gacaagtacc tatcgtgtac cgacggaacg
     5881 agtatataaa gttctgcggg aagcgacaag acagcatctg aaccaagtaa aagaagtatg
     5941 ggaagacttg ctgatgagtc tatctgtcac tcagcgagca atgcttaaag caagcgaacc
     6001 agttgcagct ggacctacag gactagtgat tgcgtttgat tatgagattg tttgtcaaag
     6061 agcagcaaat gacgaagaat tgcagctttc ggtacacaac aacttaagcc gaatgatcaa
     6121 agattatgcg cctgatcctg tttatattac aagagaaagc tggccagaac ttcgaagaaa
     6181 ttatttgacg caggcacaag aagagggaac agaaaactct tttgcttctg aagactcaga
     6241 aggagaaatc gagttgcttc ctcaagaaca agaagtacca gaagaaacac ttgtagtaaa
     6301 agcagaggaa ctgtttggct ccgaagctgt tacagtggta gatgattaat aaaaaggagt
     6361 agataattat gatgcgtgga atgggcaata tgcaaggcat gatgaaacaa gtacaaaaaa
     6421 tgcaaaaaga aatggcagaa gcacaagagc tgctaaataa aacagagttt acaggtaaag
     6481 ccaccaatga attggtcaaa gcggttttta caggcgatcg tcgcatgaaa gatatccaaa
     6541 tcaatgaaga agtcgttgat cctgatgata tcgagatgct tcaggatctt gtcgtaatgg
     6601 cagtcaatga tgcgatcgca caaattgatg tggaaactga gaaaaaatta gggaaatacg
     6661 caaaaggttt gccaggattt tagttttaaa ctgaaggagt aatgaatatg caatatccag
     6721 aaccaattgc gaaactgatc gacagctaca tgaaacttcc aggaatcggt cagaaaacag
     6781 cgacaagact cgccttttat acgatcgata tgaaagatga agtagtaaat gaatttgcta
     6841 aatctttgtt aagtgtaaaa cgcgatttgc atttttgtag tatctgcgga aacatcacag
     6901 aagaagatcc ctgcgaaata tgtagaaatc cttcacgtga tcgaagcgtt atcctagtgg
     6961 tcgaagagcc gaaagatgta atggcaatgg aaaaaatgcg agaatatcac ggactttatc
     7021 atgttctcca tggtgtgtta tcaccgatgg aagggacagg tccagaagac atcaatattt
     7081 cttctctgtt gcagcggctg catgatgcag atgtaaaaga agtgattatc gcaacaaatg
     7141 caacaacaga gggagaagca acagctatgt atctctcacg tctgatcaaa cccgcaggta
     7201 tcaaagtgac tcgtctagca catggtctgt ctgtaggctc tgatatcgag tatgcagatg
     7261 aagttacttt attgaaagct gtcgaaggaa gacgtgagtt ataaatttct aattaagtgt
     7321 tttttcagat acaatataaa agcagcacaa gagatggggg caacaatgtg aacggactat
     7381 ttattacaat cgaggggcct gatggtgcag gaaaaaccag catcttgaat gaactttacc
     7441 ctcttttgaa agaagtagca aaaacagaaa tcattcaaac aagagaacca ggaggcattc
     7501 cgattgctga agagatccga gcagtgatcc ttgatccaaa aaatgatcgg atggatgaac
     7561 gtacggaagc actgctttat gcagcagcaa gaagacaaca tctagtcgaa aaggttctgc
     7621 ctgctctggc aaaagggaaa atcgttttat gcgatagatt tgtcgacagt tctcttgctt
     7681 atcaaggtgc aggccgacgc atcggcgtta ccgagattgc tcggttgaat gagtttgcta
     7741 cagaaggtac tacgccggat tttacccttt atcttgacgt agattcagac accggattaa
     7801 gaagaatcaa gaaaaacaga caaaatcaaa tcgaccgttt agattcggaa ggtttggaat
     7861 tccaccagcg tgtacgtcat gcttacttaa agctggcaga agagaatccg gaaagaatcc
     7921 acaaagttga tgcaagaaaa agctttgaag aagtgctgca aacaagttat catacaatta
     7981 ttgaacagta tccgcaattt tttgaaaact aggaaggtga acgtttatga aaattatttt
     8041 agcgattatc caagacaaag acagcaaccg tttatcaaat gaattgattg atgcaaatat
     8101 ccgtgccaca aaactatcat cgacaggcgg cttccttaag gctggaaaca gtacgtttat
     8161 cgtgggtatt gaagatgacc gtgtagaaga agcattggaa atcatcaaaa aaacgtgtga
     8221 atcaagaaag caatttgtat ctacacctgt tacactggat atttcgatgg atgggggcgt
     8281 cccttatcca gtagaagtag aagtaggcgg tgccacagtc ttcgtcttac ctgttgaagg
     8341 attccatcaa ttttaggagg agctgagcta tgaatcaaga aataaacttg gctcaaatgc
     8401 aaccgatcgt gtatcagcag cttcaacgga gttttgagca tgggcgtatc gctcatgctt
     8461 atctttttga aggggagaaa ggaacaggaa aacatgaagt aggtatatgg cttgcacagc
     8521 acctgttctg tacccaaatg aaagacaatc tgccttgtgg aaaatgcaac aattgtcagc
     8581 ggatcgaaaa gaaagaacat ccagatgttt tggttattga accggaagga caaaccatca
     8641 aagtcgatca gatcagacgt ttgcagacgg aattcagtcg cagcggttac gaatcaagaa
     8701 aaaaagtttt tttgatcaaa gaagctgaaa aaatgaatag cagtgcggca aacagtttgt
     8761 tgaaattctt ggaagagccc cctggagatt ttttagcggt gttagaaaca gatgcagtag
     8821 gaagaattct ccctactatt caatctcgtt gtcaagttct gcattttcaa gaactttcga
     8881 aagaagcact gatccatcga ttgcaagaag agcagattcc attggaaaaa gcaaaacttt
     8941 tggctttctt aacaaacagt ttaggaaaag cagttgaaat ctctcaagat gaatggttta
     9001 atgatgctaa ggacttgatt tatcaatggt tcgtttactt gcaaaagcaa gatactcaag
     9061 cctttatcta tgtccaaaaa aaattggtaa aatcatttaa agaaaaaaca caacagttta
     9121 caggattatc tgtcttgatg ttttattatc aggaagcaca gcgtcaagca gtagcaaacg
     9181 gcgaatatgg caaagtgaaa cagataaacc agataattga acggatattg atcgcagagc
     9241 agaaactacg cagcaatgtc agttttcagg ctgttgcgga acagttcgtt ttgcatacga
     9301 ttttttagct tgccgcaaag gatgatgatc aaggaggatg gaaatggtag aagtagtagg
     9361 tgtccgatat agagatgcag gtcatatcta ttattttgca ccaggagact ctgaatatgt
     9421 ttatagtgac aaggtattag tcgaatctca gcaatcctta catattgcta ctgttgtcct
     9481 tcctaaaaaa gagattgatc ccaatgacct tcctgaagct atccgtccga tcttgcataa
     9541 agcgtcacaa gctgaattag aaaaagacaa aaaaaacaaa aaagatgctt atgatgcatt
     9601 gaaaatcgca aaagaaaaag tgcagttgcg tgagttggaa atgaaaatgg tcaaagccga
     9661 atacacattt gatcgaaata aattgatttt ttctttcaca gcggacgggc gaattgactt
     9721 tagagaattg gtaaaagatc tggccgctgt atttcgtact cgtattgagc ttcgacaaat
     9781 tggtgtccgc gatgaagcaa agataatagg cggaattggt ccatgtgggc gtccattatg
     9841 ctgttcttct tttttaggcg atttcgtgcc tgtatcaatc aaaatggcaa aagatcaaag
     9901 tttatctttg aatccaacaa aaatttccgg tttatgcgga cgcttgatgt gctgtctgca
     9961 atatgagagc gaagaatacg agacagcgaa aaaagaactc cctgactttg gaaaagtaat
    10021 tgctacacct gatggtaaag ggaaagtcgt agggttgaat ctgcttagcc gtatcgttag
    10081 tattcggctg actggacggg aaaatcctgt cgaatatgaa tgggatgaat tgaaagaatt
    10141 tatccaagta ggtgagatga atggataaga gatcattata cgacggattg aatcaattag
    10201 aatcagagtt gagaaataca ttaacagaac ttgttgaaat gaagcatgct ttgcatgaga
    10261 tcgtagaaaa aaatacaact ttggagatgg aaaatcaacg tctgcgggaa cacctgcggg
    10321 aattgaacca agttgcacaa gctccagctg aaaatgtgaa gcaggaactt tctaagtctc
    10381 gtatgaatct tgaaaaaatt tatgaagaag gattccatgt ctgctacgat ttatatggat
    10441 caagaaggga caatgacgag ccttgtgcgt tttgtctaga agtgatctat cgcgaaagcg
    10501 gtcgatgacc aataacaaga ggagactgga gcggagaaat actgctccag tctttttatt
    10561 aaggagattg tgacagatgt ataatcaaaa aagtttcaag ggaaatccgg tatatgggga
    10621 tttatatctt gtaccgacgc caattggaaa tttagaagat atgagctaca gaagtgttcg
    10681 tatgctgcaa gaatccgatc ttatcgcaag tgaggatacg cgtaatacac aaaagttatt
    10741 gaatcatttt gaaatccata caccccaaaa aagtttacat gaacataatt ataaagaacg
    10801 tgtccctcaa ttgattgctt tgttaaaaga aggaaaaacg attgctcaag tcagtgacgc
    10861 aggaatgcct tccatcagcg atcctggaca tgagctagtt ttagcctgca taaaagaagg
    10921 gatttctgtg atctctatcc caggacctac agctgggatg acggctttga ttgcttcagg
    10981 gctagtgcct caaccatttt tattttatgg cttccttcca cgtaagaaaa aagaacagaa
    11041 agaaacattg aaaaagctaa aagaacagac agttacgctg attttttatg agtcacctta
    11101 tcggatcact gctacattga cgaatttctt agaaattttt ggaaatcgcc aagtcgtttt
    11161 gtgtcgggaa ttgacaaagg tccatgaaga ataccttaga ggaagtacgg aagagctact
    11221 cgcttatatc gaagaacatc cagtaaaggg tgaatgttgt ctgcttgtag aagggaattt
    11281 gttcgaaatg ccagtgacgg aagttgatga agagttggga acgttaaagg aacaagtaga
    11341 agcaaagatc gcttcaggcg aaaaaccaaa tgctgctatc aaagcagtag cgctgaaaaa
    11401 tgggctgaaa aaacaagaag tctaccgtca gtaccatgaa ttagactgag atagtataag
    11461 ttgtctataa tgaaagacta atgaggaaat cagctactaa cttttcaaat ctcttgaacg
    11521 cgaacgaatg ttcttgtata atgaataaga ggtgaggatg atggagctgc aatttccttt
    11581 acataatgat acatcaagaa aaatcattca tattgatatg gatgcttttt tcgcttcggt
    11641 tgaagaacga gatcatcctg agtttcgcgg acatccatta gtaattgcca gacaccccag
    11701 tgacactggt gggcgtggag tagtgactac agcaaattat gaagcaagaa aattcggaat
    11761 tcattcagca atgagtgcac aaaaagcgta tgagctttgt ccgcaagcca tctttaagcc
    11821 tggcgaccat cataaataca gcgatatttc caaacaagta cgggaagtat tctatcgtta
    11881 tacagatatt gtggaaccag ttagtatcga tgaagcgtat cttgatgtga ccgaaaataa
    11941 aatcaattgc aagtcagcca tcaaaatcgc ccgaatgatc caagcagata tttgggagag
    12001 tgtccagcta acatgttctg cgggagtaag ttacaataag tttttggcca aattagcatc
    12061 agactatcaa aaacctagag gaatcacggt agttgcccct caagacgctg tgccattttt
    12121 aaaagctttg ccaattgaaa aatttcatgg ggtagggaag aaaactgtac ctagaatgca
    12181 tgagctaggg atttatacag gaaaagacct atatgaatgc acagaaatga tgttgattcg
    12241 aaattttgga aaaatgggct attctcttta tcgtaaagtc agaggaatcc atgattctcc
    12301 agtaaacgtt acaagagagc gaaaatctgt gggaaaagag catacttatg ggcagccgtt
    12361 gcaaacggaa gaagcagtgc tgactcagtt gcgccaacta gctgaaaaag tagaagaagc
    12421 actgagaaga gtccaaaaac atgggaaaac agtagttttg aaggtcaggt acacggacta
    12481 ttctactgtg accaaaagag tgacattgcc agaatatatc tataaaaaag aagcactctt
    12541 ttatcaagca agccttatat gggaggaaat cttgggagta gaaaaaggaa tccgattgtt
    12601 agggattact ttgacgaatc tggacccgat gacttatgaa aacatcgtcc ttccattatg
    12661 ggaaaatcaa gaaatataaa aacagctttg agagttgaaa ccggaaatcc gttttctctc
    12721 ccaaagctgt ttttatatca agtcttgctt tttgatttgt tcataggttt ctgttgcatc
    12781 cgtacatttt tcccaaatca caacttgatt ggattctaaa gatttttgga cgtcaatgat
    12841 ccgctggttg ctacttccgc gaaattgtag ttttaggtca cgtttgctta attcaaagcg
    12901 tccgtcaaca aggatatcga tttgcgaaag gagttctaat ttatcttctg aatcttgtag
    12961 caattcatca aaggtatagc ctgtccatga ccagatatct tttgtcgtac cgaactcttt
    13021 tcggatacgt cgtacgactt gcagacaaac atctgtattc aaaaaaggtt cgccaccaag
    13081 taaagttaat ccttgcacgt aatcgttgcg caagtcagcg atgatttgtt cttctaattc
    13141 aggtgtgaat ggtttgccat atcgaaaatt ttgtgcagct ttgttgaagc agccttcgca
    13201 ggcaaataag cagccactaa cgtaaagact gttgcggaca ccttcaccat cgacaaaatt
    13261 aaacggtttg tagtcagcaa tatagttttg gctgtagtct tttgctaacc attcttttgg
    13321 ttttggattt ctcataaaaa aacttctttc atttaaggtt caaagatata gctattgaag
    13381 ataaaatcta ctcgaccaca taaataagaa caaactgacc taaatccatt gttcaagaaa
    13441 gcttgttctt attttgatag agggcgttca aagatacaaa gccatcgaaa gagggtggtg
    13501 aaaaaagact tgtcatagcc tcttattctg aataaacggt gttcaaaagc ttgcatctgc
    13561 agtaataagc ccaactaaac gaaaaatatg aggaactatt tttgtttagc tattcttatt
    13621 acttgatgca ggacagcttt ttcacaacct catttcatgt gtttcacacg tgaggaaatt
    13681 tctttatggc ggccatgtac catcggacga gcttgcggat ttcctaaata gccacaagta
    13741 cgtttgacta catcacatgt ttttggatca tgatttccac attctggaca ttcgaaccct
    13801 cgttctgtcg gtttgaaatc accttcgaaa ccacattgat agcaatgatc gattggcgta
    13861 ttcgtaccaa gatacccgat tttgtcatat gcaaaatccc atacagcttc taaagctttc
    13921 ggattttgtt ggagcatagg gtattcacag tagtggatga atccacctga acaatatttt
    13981 ggataatcct tctcaaattc caatttttca aatggcgttg ggtttttacg cacatcatag
    14041 tggaaactgt ttgtataata ttctttatct gtgatatttt cgatgatgcc gaatttttct
    14101 gtatccaaac ggcagaaacg gtcagttaga ctttcacttg gagttgaata gacactgaaa
    14161 tgataaccat attcatcccc ccatgcatct gcattagctt ttaattcttt gacgatatca
    14221 agtgtgaaag cttttgcttc tgggtttgtt tcccattcgc caccgaagaa agctgaagca
    14281 acttcataca atccaatgta gcctaacgat acagtagctc gacggttttt gaataattca
    14341 ttgacagaat cggtacgtga aagacgtttc ccgaaagcac catacatata taaaattggc
    14401 gcatttgctg gaatggcttc tttacaacgt tctacacgat agagaagcgc atctttcatg
    14461 atttctaagc ggtcagacag taactgccag aatttattct gatctccttt tgattcgatc
    14521 gcgattcttg gcaaattcaa tgtaacaaca cctaaattca ttcgtccgac atttacttct
    14581 tgaccatttt cgtctttcca cccttgcaag aatgaacgac agcccatagg tactttgaaa
    14641 cttccagtta attcaacgat tttatcgtaa ttcagaatat caggatacat tcttttcgtt
    14701 gcacattcca atgctagttg tttgatgtcg taattaggat cttcagggtt taagttcaca
    14761 ccttttttca aagtgaagat cagtttaggg aagatagctg tccgcttttc actccctaat
    14821 ccattgattc gaatctgtaa aattgctttt tgaatttctc tttcaaacca gttttctcct
    14881 agtccaaatc ctaatgaagt gaaaggagtt tgtccatttg aagtaaataa ggtattgatt
    14941 tcatattcca aactttgcat agcatcgaag atatcttttt tggtttttgc ttttgcatat
    15001 tctttttggc gttctggcga atcgatccat tcttccgcgt cttttagatg ttttttatag
    15061 ttcaattctg caaaaggagc aagcaattca tctgttcggt cggcagaaca gccaccatat
    15121 tgacttgacg ctacattggc aataatctgt gagatttgtg ctgtggcggt ctggatagat
    15181 tttggcgatt cgacttcggc attgccgatt ttgaacccat tgttcagcat gcctttgaaa
    15241 tcaatcaagc agcaattcgt catcggtgta taaggatgat aatccaaatc atggtaatgg
    15301 atatcgcctt tttgatgcgc atttgctata tgtggtggca acattttcag tccgattgat
    15361 tttccaacga tcccggctgt cagatctcgc tgtgtattga aaacattact gtctttattt
    15421 gcgttttcgt tcacgacagt ttggtccttg ttgattagct tttcaatcga aaagttgata
    15481 tctgttgctt tactgcgagc aaaatctcgt ttggtacgat aattgatgta ctcttctgct
    15541 aattcatatt cgtttttttc tagtaatata tgttccacga tgttttgaat ctcatagatt
    15601 ttgacatttt cagcaaaccg gcttttgatt tcttggacaa ccaagtctgc aatcatttga
    15661 attttttcat aagtaagtgg tgataatgag ccgtgaattt tcttttctgc tttgatcagt
    15721 gcttcattga tcttttgttc atcgaaatca acatggcggc catcgcgttt gatgactttc
    15781 atctgggatg tctctggctg ctgagtaacg acagtttttt cttcataatt tactttcatt
    15841 atcttcaact cctgctaaat tgttcttgtc tatcataaaa caaaatcggg gaaggagcaa
    15901 ctaaatatcg gctatatata gtattcaatg tgctgtataa ttggatttct atactatatg
    15961 tagtgtatat tttattgtga aaaaaggtga aaacttgtag ctggtggatt tgttttttgc
    16021 atatttaatt ttgctgaata aaataattga ataaaatttt ttattcagtc caagtaaaag
    16081 tgacaaaaac ataagagcaa attattcgta gatatgctac tatgcaaata aatagaaatg
    16141 aaaaatgaaa gaggaggaga agaattggaa aagatgatcg aagtgaaaca tctaagtaaa
    16201 agctacggca gcaaactttc tcccgtcaaa gccttagata atatctcatt cacagtagaa
    16261 gaaggcgagt ttgttgggat tatgggccca agtggtgcag gaaagacaac gctgatgaat
    16321 atcttgtcca cgatcaattt gcctacgatg ggcagtgtct cgatccaagg aaaagaaatc
    16381 acaaaaatga aaaacagtga gctcagtgac tttcgtcgaa aaaaactagg attcattttt
    16441 caagagttca atttgatcga taccctaaat gcaaaagaca atatcctatt gcccctagca
    16501 gttgaacgga tgactaaaga ggaaatggaa aagagagtaa gacatgtagc tcaattgttg
    16561 aatatagaag aactgctcaa acggtatccc gatgaacttt ctgtcggaca gagacaacga
    16621 attgcagctg ctagagcact tgttgttcag ccacaagtga tttttgcaga tgaaccaact
    16681 ggctctttgg actcgaagtc ggctacagaa ttgttgaact acttgaagac catgaatcaa
    16741 aaagaaaaag caacgatact gttagtcacc catgatccat atacagcaag ctactgcgat
    16801 agaattttat ttattaaaga tggtgtgatt ttttctgaag ttgtcagaag agggacaaga
    16861 agagagttct ttgagaaagt aatagacatg caggcgacga ttggcggagg aggaaaaatg
    16921 aatgctgtat aaactagccg ttaaaagttt ttttcggcag tcacgaggct atcttgttta
    16981 ttttttcagt ttgactttat ccgtaatgat ctattattcc ttcagcgcaa tgacctacga
    17041 tcaatcttta gtcagaagag caagtcaaga tacttcgata gatggtggat tgagttttgg
    17101 tggatttatc attactgttg ttttgctttt tttcgtattc agtgccaacc gatttttctt
    17161 gaatagaagg caaaaggaaa taggcatcta tcagcttttt ggtatgaata aactgcagat
    17221 atcaggtata tatgtgttag aaatcatgat aattggattg ttcgcctgta tttctgggat
    17281 attactcggt attatttttt ccaaactctt ttcaatgatt ttggttcgaa tgatggatat
    17341 ggatcttact agtccatttt ttatctccat tccatcagta gtagatactt tatttgcttt
    17401 tttcatcatc cttttagcag tatctgtata ttcaatatgg aaaatatggc gctatccaat
    17461 gattcgaagt tttggagaaa aagaacaagc agatagttca acaatgcgct tcaggacaag
    17521 gcaccgatta ctcgcagtca tcgggttact acttttaacg agcggatatt ttggagctag
    17581 tcattttagg gaaatcactt catggatgat cagttatcat tatcttgata cattagtttt
    17641 cttttttcct tttttaattt ttttcgtttg tgtggtcggt acttatttgt ttttctgtta
    17701 tacatttcgg ttatttttga tcatattgag taaatggaag atttattact atggtatcaa
    17761 ttttttgata atgggtaaca cgcaagttca tttgctcaaa agttggcgta caaattctct
    17821 gattacagtc attctcggaa tttctttaat gacaattggc ggcacggcta gtatctctac
    17881 tattttatcc taccaggaga aagtttcctc cccgatggac tatcagtttg atgttgagac
    17941 agagaaaaaa atcaagccga ttctagcaga ggaagggcag aagataacta aagaaatcac
    18001 cttgcattat aaagtcattg ggagtatcta tagtcaaaat ctcgaagaac ctatgtttca
    18061 aactgctaat ctgatcacgg aaacacaata tcaagccttc agaaaagtta atccagattt
    18121 gccgaacatt tctttgaaat cacctggtca tactgttttg cttgatcaaa tgcaaactct
    18181 ttttcggaat atttcattat atggatctag tattggactg ccagataatc aagaattgaa
    18241 gattcaacaa atgcttccaa gtgtattagg tgacgaaaca atggtatatc taagtcctgt
    18301 actgattgta gatgataccg tttttgaaaa agcaaaaggt gtggattatc aagtagtcaa
    18361 tgtagatgta tcaggtggaa ataatgaaaa aatagatgaa cgactgagca atgacctgtc
    18421 gataaagtgg ctcaatgctg tttattattc ttatgatatc gtaaatggaa gtctacaagg
    18481 agaaattagc acaaagaaac ttccggatga ccaaatgaag gaagcacaat ttagccaaga
    18541 aagctctcgt ttgaatttct cttccagcta ttcgaaattg cgtgcagtta atcggcgaat
    18601 cggtatcaat atttttgtca cactatttgt cgggatgatc gtgattattg ctactggtag
    18661 tattttgaca gtccggcaat tagcagaagc agaggaagaa aaagaaaatt atcacctatt
    18721 gactaagctg gggattccac aaagaaggat cagacggatg atcttcgagc aaaacgcact
    18781 taccttcttt ccacccatga tattagggat cactcacgca gtatttgcaa tcaatgtctt
    18841 cactcagtat ataaaaactg ccgattactg gttggcttat cttgtgagtg gcttattgat
    18901 ccttatctat cttttgcttt atgtcattac gagtcagtta tattgtcgga ttatcgagga
    18961 atgatatacg gaataagaca agataataaa tagaactaaa ttttgaatac catttatttg
    19021 gaataagagg ttgtgacacg atttttgtca caacctcttt attttttata ttttttaaaa
    19081 gtacgagaaa ttataaagaa aaaagcagtg atttgatgtg ctatttttat aaaagctatg
    19141 tgacaaaact gttagtaaaa aaacggtttc tgtaagctag acacatgttt ctttttgtca
    19201 aaattagtta cactttgtgt gaggttatat gaggagggaa tccaatgaac aaatggcgtt
    19261 ctaatccaaa attgaattat tggggaaaat tcatcattcg aacaattttt tatagtgcag
    19321 tactgctgtt cctgatttat ctgtatcact ataaaaatat tcaaggagga acttttatct
    19381 ataacgaatt ttaggaggaa gagtatggaa atcaaaacga ttattgaagc aatcgatgat
    19441 tggggaataa atgaacctga tcgagttgct tatcaggcgg atgagacgca tacttttggt
    19501 gaattgaaac aagcatcaga cgcacttgct tattatttag aaaaaaaggt agaaggcgat
    19561 ggaccaattg tcgtttttgg caatttggag tttgaaatga ttgtctcatt tctaggggtt
    19621 gtcaaatctg gccatgccta tttgccgatt gaagagcata cacccaagga gcgtatccta
    19681 tcgatctttc gggtggctaa accatctatg gtcatcagta tcggggactg gatagaagat
    19741 attccttcgg ttcctgtcat aacaaaaaaa gaatttcaag aaatcaagaa gataccagta
    19801 ggattttatc ccagaaatag cgtaaaaggt acagaaaatt tttatattat ttttacttct
    19861 ggtactactg gagaaccaaa aggcgtacaa atcagtcatg ataatctagt cagctttgtt
    19921 caatggacga tggaagactt tgggatcaag cctggtatgc atttcttagc ccaagcgcca
    19981 ttttcttttg atttatcggt attttctatt tatcctgcat tagtttctgg cggaatgctg
    20041 aagccgttaa ataaagcagt tgttcaagac tttcgtcaat tattcgcgac attgccagcc
    20101 ttgaagttga atgtgtgggt ttctactcca tcatttatgg atatttgctt gatggaacct
    20161 acattcaatg gagaaaatgt gccggaattg gacatgtttt tattttgcgg agaagaattg
    20221 acgaaaaaaa ctgcagaaag tctacttgat cgattcccaa atgcacggat atataatact
    20281 tacggtccaa cagaagcaac tgtagctatt tcaagtattc agattgacca gcatgtacta
    20341 gatagttatg accgactacc gattggctac gtaaaaaaag acacgaaagt ttctattgtc
    20401 caagaaggta aacctgtttc aaaaggagaa acgggtgaaa tcattattgc aggaccaagc
    20461 gtatcaaaag gttacctgaa caatcccgaa aagacagctg ctgcgttctt ttgtcaaaat
    20521 gacttagcaa gttaccatac aggggatgca ggtagactag atgaatatgg gcttttattt
    20581 tatgaaggac gtatggatca gcaggtcaaa ttacatggat accggattga actcggggat
    20641 atcgaacatt atctgctcca agacaaccga atcaaacaag ctgtcgtcgt accaaaatac
    20701 caaggaacaa aagtacagca gctggttgct tttgtcgtat tagaaaacaa aacgaaacag
    20761 ccggattttc agttgactaa atctatcaaa gaacaattac tagaagttgt aatggattat
    20821 atgattcctc agaagttcca ttatgtcgat ctgctgcctc agacagttaa tggaaaaatc
    20881 gatcgaaaaa aattaacagc tgaggtgaat cctgaatgat gttacctcat atgatccctt
    20941 atgcagagcc gttttatttt tttcttttag ccattgcgct tgtaccgatc gttctatctt
    21001 tattgatatg ggaaaaaaga ttaccagttt atcaatcagc agtgacactt ttctttttat
    21061 ttgtcagctt tggaggtaat tattggcaac agggagcggc gctgattggg tatgttttgt
    21121 ggcagacgat acttgtatgg ggctattttg tttatcggca aaggaaaaat cagacaggat
    21181 ggttttttgc cgccgttatt ttagcgataa ttccactgtt tttaacgaaa gtgactcctt
    21241 tttttgaaca tggaaaagca tcgttacttg gttttttagg aatctcttat ttaaccttta
    21301 aatctgtaca aatgatcatg gaaataagag atggcatgat caaaacatat aagccatttc
    21361 gttatatcca gtttctgctg ttctttccaa caatctcttc tggaccaatc gatcgctata
    21421 ggagatttga aaaagatcag ctccatccgc ctgttcgtga taaatatgtt gatcttttgg
    21481 gaaaaggcgt ccaaaatatt tttgtcggtt ttttatataa attcattatc ggttattatt
    21541 ttggtcaagt actgcttcct gtagtgggac gcattgcctt acagcatggt ggtatttcat
    21601 gggcattagt aggttatatg tacgtgtaca gtatgtattt gttttttgat tttgctggct
    21661 atagcttatt tgcagtcggt acaagctaca tgatgggata tcagacacca atcaatttca
    21721 ataaaccttt tttatcatgg aatatcaaag aattctggaa tcgttggcat atgacgctgt
    21781 ccttttggtt ccgtgattat gtatatatgc gattgatgtt cttcatgatg aagaaaaaat
    21841 tttttaaaag caagatcgta atgtcaaata tcggttattt tgctttgttt cttctaatgg
    21901 gtatatggca tggattgacg tggtactaca tcgtatatgg actgtatcat gcttgtctga
    21961 tctgtctgac agatgcatgg atccgattta agaagaagca taaagagcag ttgccttcta
    22021 acaaatttac gcatggctta gccgtatttt tgacatttca agcagtatgt tttagcttcc
    22081 tgattttttc aggattttta gataaacttt tttttagcta acgaatagtg acatattaat
    22141 ttatataaca aaggagaaaa ggaaaatgga agaacaaatt ttatcaatct tagaagaaat
    22201 aacaggaaca gatgaagtaa gaaaaaatcg tgatattgat ctatttgatg aagggttgct
    22261 tgattcttta gcatctgttc aattattagt cgagctagac ggagagctgg atatccaagt
    22321 ccctgtatct gaattcgagc gagaggattg gtgcacaccg aataaaatca ttcaacaagc
    22381 aactgcattg aagggttgag tatgaaaaag aaactttttg ctattttcgg cccggttgtt
    22441 ttagctgttg gcttactgtt tgtgtttttt acctcctcct atcaagtaga tatctctaat
    22501 ccagaaacga ttagacgtgc ctcttcttcc atgtcagtga acgtgttgaa aggagatgcg
    22561 ataaaaaatt atgcattatc tgaaaaacaa tatattcctt tttttggctc aagtgaatta
    22621 agcagaatca gtccatttca tccgtctgtt ctggcagaaa aataccagcg aaactatcgt
    22681 ccatttttgc tgggagcacc cgggacacaa tcgttaagcc aatatatgat gatgcgttct
    22741 gcaggagatg ctatgaaaaa caagaaagtc gtctttatta tttctcctca gtggttcgtt
    22801 aaaaatggtg taaaaactga ttactttaat acgtattatt ctgaacttca aacatacgac
    22861 tggttgtttt caatgaagaa agtaacgcct gctgatcgct atttagctag aagattatta
    22921 actttctcaa aagtaaaaga gaatgatacg ttgacggcga ttctgcaaac gatcaaaaaa
    22981 gggaagctac ctttacctga atctttgaat cagctgcgca gccaatggaa catgctgaag
    23041 agagaggatg aagtattcag caatattggg ttgaaagatc gacagcaaaa aatcgatcat
    23101 gagtcaaaac gattaccaaa acaataccaa gaaacagaat tatccatttt agcaaatcaa
    23161 attggagaac gagaaacgac gaataatcca ttcgggttga aaaacgattt ttatacgcat
    23221 cgtatccgag cccacgagcc agagctcaaa cagtcacaaa aaaattggga ttatcgtttt
    23281 tcgccagaat tttctgattt tcagctggtc ttggatcaat tagcaaaaaa ccataacgaa
    23341 gtattgttca tcatcccacc ggttaacgag aaatggagcg attataccgg actatctcaa
    23401 gaaatgttac aaggatttgc caaaaagatc aaatttcaat taaatagcca aggattcaat
    23461 cgaatagctg attttgtcaa tcaagcgggt accaactatt ttatggaaga cacgatccat
    23521 ctaggctgga aaggctggtt ggctgcagat caacagatca gaccgttttt agaagaaaat
    23581 catattactg ctagtaagta tcatcttgac gatgcttttt ttagcaaatc ttggcaacat
    23641 caaataccag ataaactaca attaaaataa agaaaacagg cgagtgttgc tcgcttgttt
    23701 tctttatttt tgaatattct gaataaaaga taaaaatacc aagtttgcct gaacaaaaat
    23761 cataagcaat ggtataatca caatatgaat atagaaatgg gggaaaacat ttggatacaa
    23821 aagaagaaca gctacttatt gatttaactt ctgcaaaagg agtacctgga aatgaagaag
    23881 aggtaagaga agtattcaga gaatatgcca aaccattcgc tgatgatatt ttttatgacg
    23941 gtttaggcag tgtgattgcc aaacatggtg ctggcggagg ccccaaggtc tttatttctg
    24001 gacatatgga cgaagttggt tttatggtaa caaaaataac cgaaaaagga ttcttggaat
    24061 tccaaactct tggaggttgg tgggggcaag tcatgcttgc tcagcaagtt gaaatcaaaa
    24121 cacgtgaagg gaaaatcgtc cacggtgtga ttggttccaa accaccacat gttttaacac
    24181 ctcaagtaag aaataaacct tatgaaataa aggatatgtt cattgatatt ggcgcatcaa
    24241 gccaagaaga agccaaagag tggggcatac gtcctggaga tatggtcact ccatatattg
    24301 aatacaaacg aatgaatggc agtaaatatt tactggcaaa agcatgggat aatcgtatcg
    24361 ggacagctgt ttctctgcga gtattagaga atctatctaa agaagcacac ccaaatgttt
    24421 tattcgcagg aagcgatgtg caagaagaag taggcttgcg aggtgctcga acaagtacac
    24481 accttgtaaa tcccgatatt gcttttgctt tagatactgg tacagcagga gacactccag
    24541 gaatgacacc aaaagaagca gattcgattt taggaaaagg cccacagatt ttgatttttg
    24601 atgcatctat gatcccgcat aaaaaattat tgaattttgt tattgatgta gcagaggaaa
    24661 tggatattcc attccaatat acagtgattt ctggcggagg aactgatgca ggacaaatgc
    24721 atttgacaag agatggtgtt ccgtctgtag ccattaccgt tcctgttcgt tatctgcatt
    24781 cccatacatc agtgattcat gaagatgatt atttgaatac agtgaaacta gtcacagaat
    24841 tagtgaaacg gcttgatagt gaaacagttg aaaaaattcg gagttatgaa taatgaataa
    24901 tagaatacct atttctgaat atcggaaaaa agcacgagtt tctttggaaa atcaatgggg
    24961 aatcaatact tggcttgttt tcttatctat aatatttacg agcgtcatcc agaacttttt
    25021 tgacggtttc agtccttttc cggaagaaag catgcagcag cacttattga gttttctagt
    25081 cgataattta cttttattcg cattcaacta tgcattgttt tacattgcgc tagtagttgt
    25141 acggggtggc agaccaaaaa gtaacctttt attttcagtt ttccaaagaa agtattttgg
    25201 ttcgatactt ggcatcaatt tgatcaattc agtcatcaac tggctactca acagtttaat
    25261 ctttctgccc atgtttttaa tcagcggagt gagtacttat atgcagctgc ttttcagttc
    25321 aaatgcggta cctacgggtg tcatgccaga agattttctt gatatcagct ttgttttatc
    25381 gatgataggg atgatttttg tttcagcact catcatgagt attgttggcg gtttattcca
    25441 atttgctgca tggacaaagt tcgactatcc tgatttgtcg gttattcaat gtttgaaata
    25501 tggctggttt ttattgaaag atagaattgg tacgtatatt ttgttgcagc tgtcttttat
    25561 cggctggtat ttgctaggag caatcgcttt gttcatcggt cttttgtggg tcattgttta
    25621 tgtgaatgtg tcagttgcag aattttatga acaagcacgg attgaaaaag gaggtccaga
    25681 cgcctatttt acttagcatg taagcagttt attcatcaaa aaaataactt ttgtggtagg
    25741 ataaatcttt gagggggaat gtacgatgaa attaactgtt ttaggatgct taggagcgta
    25801 tccttataaa aatcaaggga caacaggtta tttgcttcaa tctgacgggt tcaatttgtt
    25861 gatcgatgca ggtagtgcta cgctgatcaa attacaagaa caccttgatc cacttgatct
    25921 agatgctgtg atccttagcc attatcatca tgatcatatt gctgaccttg gtgtattaca
    25981 gtattactgg caacttcatc ctaagagaaa tccggagaca ttgctttcaa tttatggaca
    26041 cacaaaagat tccattcact ttgaagaatt gacgttggaa aatgtctcaa aaggacatcc
    26101 ttattttgaa gctgaagaat taaaaattgg tccttttctg attactttta tggaaacaat
    26161 ccatccagta gtatgttacg ccatgcgtat cgtagaagaa acaacgggga aagtattcgt
    26221 atttacaggt gattcaggtt atttggaaag tttcgctgat tttgcgaaag atgctgattt
    26281 gtttctagca gatacctatc tttttgaagg aaatgaacat catcatgccc atttcacttc
    26341 aaaagaagct ggagaacttg cgaaatcagc taacgtaaag aaacttgtac ttacacacct
    26401 acctcagttt ggtgatttag aacaattgaa aaatgaagcg caaaaggcag caggcaaagg
    26461 gattgatata gaacttgctg cagttgacaa agtgtttaac atttaggagg aagaacatga
    26521 tttttgtacc aaatgaaaac cacgacccaa gaatcaattt agcaattgaa caatatttgc
    26581 tgcaagaaat gcctttagat gaacctattt tgctctttta tatcaatgaa ccttcaatca
    26641 tcatcggcag aaaccaaaat acgcttgaag aaatcaatcg agattatgtg gaagaaaatg
    26701 gcattcatgt tgtccgtcgc ttaagtggag gcggagctgt ctaccatgat tttggaaacc
    26761 tgaactttag ttttatcatg cctgatgatg gggattcatt ccgtgacttt gcgaaagtaa
    26821 cacagccaat catccaagca cttcatgaat tgggtgttgc tggggcggaa ttgaaaggcc
    26881 gaaatgatct agtcattgat ggcatgaaat tttctggcaa cgcgatgtat gctaccaacg
    26941 gtcggatgtt tgctcatgga acaattatgt tcgactctga tatcaatgaa gtagtcaatg
    27001 cattaaaagt aaaaaaagac aaaatcgaat caaaaggaat caaatcgatc cgttctcgtg
    27061 taacgaatat caaaccattt cttccagaag aaaagcaaaa aatgacaaca gaagaatttc
    27121 gtcaagaaat cttgttgaaa attttcggcg tagagtcagt agaagaagta aaaacgtacg
    27181 aattgactga tgaagattgg aaaaaaatca atcgaatctc tgaggaatat tatcgaaatt
    27241 gggattggaa ttacgggaag tctccagatt tcaatttctc tcgccaaaaa cgtttttcta
    27301 tcggttcgat tgaagtccat ttgaatgtct cagaaggaat gatcaaagaa gcaaaaatct
    27361 ttggcgattt cttcggacta ggagatatct ctgacgtgga aaaaaaattg gttggacaga
    27421 aatatgataa agcatctcta tcaaaaatag tcagccaaat tgatgtgaag aaatattttg
    27481 gtgcgataga accagaagaa ttgcttacct tactttattg aaaataaaaa atagcggaat
    27541 ccacatatat ggattccgct attttttata caggattcgg gtaatttcga gagagttgaa
    27601 cagtgatccg atcaatgaaa gtatcttttt cctgcgttag tgttcctgtg taacgatccg
    27661 ctacgtcttt catcatcatt aagtcaaaac gttcctgatc atctaattct tctgtgatgc
    27721 ctcgactaaa taggtttgta tcgtaatgtg cactatgttc gcaacaaatg acgaaatgtt
    27781 cctcttgttc gtgtatcgac aaataaattt ttcgatacag tggattttcg atggcatgag
    27841 tttctctaaa ggaatgctct aaagcgtgga tcaaaagttg agccagatcg tcatcgttga
    27901 taggaagttc ttcgggaaga tctgcttgga aggttatctg aatattccgt ttggcagcta
    27961 acttctggta acgcgctaag ataagatttg tcacctggtg gttgcaaaaa gaacacagca
    28021 tttcgaaatt ttttgcttct tctaatatct tttccacata gtttttagct tttgtttggt
    28081 ccgtatgcat taaatcttgc agattctcca tctcttggac aaattccagg cgaagtgtat
    28141 ttacttcttg gatatgctgt cgaagctgct cataatgttg ctccaacaaa tcatttttga
    28201 tttttaagaa atctacttgt ctccgatctt tgtcggtatt taagatgtga tcgattagat
    28261 tgtagctgat aataacgatt agaatgataa tatataaaat cgtagaccaa ttgatcgttg
    28321 tttgatagat acctaatgcc gtttggatgt aaatcaagca atggataatg gctaccaaga
    28381 cgatccaagg tgtacaagct acataaaaac ggttattctt atatgcttcg ccaatgcatg
    28441 caagtgaagt gactaaagtg cttataacac tagcaatatt agcaatcggc attaattcag
    28501 gaagttctgc aggagtaaaa gttgcataaa gcagaacgcc gataaaaatc aaaagttgga
    28561 acgtacaaaa aattccgtac cattttttat agtaaaacat tcggctccaa tagtagcaga
    28621 tgatgaaagc tgacgttaag ataataaata aatgagataa aaaagaatga acgaatggtt
    28681 caaaaagaat accacttaaa atatcttctg atacagcttc aaatcctaat gccaaagcaa
    28741 agcaacttaa gagaataagt gagtattcaa gacgtttttg tttatacatc aagtagatcg
    28801 tatagaaaaa ggtccctata gcgataaaaa cagcgattat catcgtcaat acttgcggca
    28861 ctgattgtga ataaataaaa ctaatcaatg gtccagttgt tcctagataa actttcggtg
    28921 gcagtccagc atagttctga taaggagatg agactgtaag ggtcaatttt tttccgatat
    28981 aatttgctgg taaatctatc acagccaatg agagtccggg attgctttct tcctgataat
    29041 ctttccgttg gtataaaatc ttttcgccta gatatacagt aatccattga tggtttcctt
    29101 tgattagtaa atttgcttcg tccaacggtt tttcaagtgt cgtttccata atgaatgttt
    29161 cgtctttatc cacggtagga atcgtacgag tgtacttgct gtcaaactta aaatcaggat
    29221 catcttttgt atagaaaacc cacgaatctt ttatttcttt catttgattg ctgtccgcag
    29281 gagaaaaaat aaaataaaag aaataagcaa ttcctgttaa aaataacaat
//
LOCUS       DADVXK010000025        28139 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.025, whole genome shotgun sequence.
ACCESSION   DADVXK010000025 DADVXK010000000
VERSION     DADVXK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.025"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(96..575)
                     /locus_tag="KB909_001025"
     CDS             complement(96..575)
                     /locus_tag="KB909_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6837076.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(648..932)
                     /locus_tag="KB909_001026"
     CDS             complement(648..932)
                     /locus_tag="KB909_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837077.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(1010..1204)
                     /gene="ssrS"
                     /locus_tag="KB909_001027"
     ncRNA           complement(1010..1204)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KB909_001027"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(1276..2562)
                     /locus_tag="KB909_001028"
     CDS             complement(1276..2562)
                     /locus_tag="KB909_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBB6837078.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            2700..3371
                     /locus_tag="KB909_001029"
     CDS             2700..3371
                     /locus_tag="KB909_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBB6837079.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            3337..3825
                     /locus_tag="KB909_001030"
     CDS             3337..3825
                     /locus_tag="KB909_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBB6837080.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            3838..4785
                     /gene="prmA"
                     /locus_tag="KB909_001031"
     CDS             3838..4785
                     /gene="prmA"
                     /locus_tag="KB909_001031"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBB6837081.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            4786..5550
                     /locus_tag="KB909_001032"
     CDS             4786..5550
                     /locus_tag="KB909_001032"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBB6837082.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            5783..7996
                     /locus_tag="KB909_001033"
     CDS             5783..7996
                     /locus_tag="KB909_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBB6837083.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            8007..8453
                     /locus_tag="KB909_001034"
     CDS             8007..8453
                     /locus_tag="KB909_001034"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBB6837084.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            8624..9883
                     /locus_tag="KB909_001035"
     CDS             8624..9883
                     /locus_tag="KB909_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBB6837085.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(9972..10919)
                     /locus_tag="KB909_001036"
     CDS             complement(9972..10919)
                     /locus_tag="KB909_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6837086.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            11313..12605
                     /locus_tag="KB909_001037"
     CDS             11313..12605
                     /locus_tag="KB909_001037"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBB6837087.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            12620..14389
                     /gene="aspS"
                     /locus_tag="KB909_001038"
     CDS             12620..14389
                     /gene="aspS"
                     /locus_tag="KB909_001038"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBB6837088.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            14498..15373
                     /locus_tag="KB909_001039"
     CDS             14498..15373
                     /locus_tag="KB909_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6837089.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            15639..17522
                     /locus_tag="KB909_001040"
     CDS             15639..17522
                     /locus_tag="KB909_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6837090.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(17597..17881)
                     /locus_tag="KB909_001041"
     CDS             complement(17597..17881)
                     /locus_tag="KB909_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6837091.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(17871..18605)
                     /locus_tag="KB909_001042"
     CDS             complement(17871..18605)
                     /locus_tag="KB909_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBB6837092.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            18734..19357
                     /locus_tag="KB909_001043"
     CDS             18734..19357
                     /locus_tag="KB909_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBB6837093.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            19549..20670
                     /locus_tag="KB909_001044"
     CDS             19549..20670
                     /locus_tag="KB909_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBB6837094.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            20677..23805
                     /locus_tag="KB909_001045"
     CDS             20677..23805
                     /locus_tag="KB909_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBB6837095.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            23824..27018
                     /locus_tag="KB909_001046"
     CDS             23824..27018
                     /locus_tag="KB909_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBB6837096.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(27164..27871)
                     /locus_tag="KB909_001047"
     CDS             complement(27164..27871)
                     /locus_tag="KB909_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6837097.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT         9371 a         5020 c         5989 g         7759 t
ORIGIN      
        1 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
       61 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
      121 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
      181 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
      241 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
      301 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
      361 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
      421 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
      481 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
      541 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
      601 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
      661 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
      721 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
      781 aaaacagcat atgcagctcc gtaaaattgt aggaatcctt gatttttatc atttttgttg
      841 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
      901 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
      961 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
     1021 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
     1081 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
     1141 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
     1201 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
     1261 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
     1321 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
     1381 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
     1441 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
     1501 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
     1561 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
     1621 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
     1681 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
     1741 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
     1801 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
     1861 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
     1921 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
     1981 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
     2041 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
     2101 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
     2161 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
     2221 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
     2281 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
     2341 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
     2401 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
     2461 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
     2521 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
     2581 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
     2641 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
     2701 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
     2761 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
     2821 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
     2881 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
     2941 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
     3001 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
     3061 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
     3121 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
     3181 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
     3241 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
     3301 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
     3361 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
     3421 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
     3481 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
     3541 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
     3601 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
     3661 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
     3721 gaagctgtat tcgagcttca ctgggataat cagcaactag cagaattagt agaagtaaaa
     3781 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
     3841 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
     3901 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
     3961 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
     4021 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
     4081 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
     4141 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
     4201 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
     4261 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
     4321 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
     4381 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
     4441 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
     4501 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
     4561 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
     4621 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
     4681 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
     4741 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
     4801 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
     4861 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
     4921 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
     4981 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
     5041 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
     5101 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
     5161 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
     5221 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
     5281 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
     5341 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
     5401 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
     5461 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
     5521 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
     5581 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
     5641 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
     5701 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
     5761 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
     5821 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
     5881 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
     5941 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
     6001 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
     6061 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
     6121 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
     6181 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
     6241 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
     6301 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
     6361 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
     6421 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
     6481 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
     6541 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
     6601 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
     6661 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
     6721 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
     6781 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
     6841 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
     6901 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
     6961 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
     7021 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
     7081 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
     7141 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
     7201 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
     7261 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
     7321 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
     7381 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
     7441 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
     7501 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
     7561 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
     7621 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
     7681 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
     7741 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
     7801 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
     7861 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
     7921 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
     7981 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
     8041 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
     8101 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
     8161 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
     8221 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
     8281 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
     8341 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
     8401 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
     8461 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
     8521 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
     8581 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
     8641 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
     8701 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
     8761 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
     8821 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
     8881 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
     8941 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
     9001 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
     9061 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
     9121 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
     9181 aaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
     9241 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
     9301 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
     9361 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
     9421 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
     9481 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
     9541 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
     9601 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
     9661 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
     9721 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
     9781 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
     9841 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
     9901 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
     9961 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    10021 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    10081 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    10141 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    10201 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    10261 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    10321 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    10381 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    10441 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    10501 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    10561 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    10621 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    10681 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    10741 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    10801 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    10861 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    10921 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt
    10981 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    11041 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    11101 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    11161 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    11221 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    11281 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    11341 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    11401 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    11461 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    11521 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    11581 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    11641 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    11701 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    11761 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    11821 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    11881 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    11941 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    12001 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    12061 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    12121 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    12181 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    12241 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    12301 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    12361 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    12421 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    12481 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    12541 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    12601 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    12661 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    12721 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    12781 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    12841 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    12901 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    12961 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    13021 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    13081 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    13141 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    13201 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    13261 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    13321 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    13381 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    13441 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    13501 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    13561 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    13621 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    13681 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    13741 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    13801 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    13861 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    13921 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    13981 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    14041 ttatgatatc gtcttgaacg gttatgaact aggcggaggt tctatccgta ttcatactcg
    14101 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    14161 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    14221 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    14281 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    14341 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    14401 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    14461 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    14521 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    14581 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    14641 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    14701 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    14761 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    14821 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    14881 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    14941 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    15001 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    15061 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    15121 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    15181 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    15241 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    15301 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    15361 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    15421 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    15481 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    15541 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    15601 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    15661 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    15721 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    15781 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    15841 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    15901 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    15961 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    16021 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    16081 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    16141 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    16201 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    16261 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    16321 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    16381 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    16441 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    16501 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    16561 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    16621 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    16681 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    16741 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    16801 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    16861 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    16921 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    16981 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    17041 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    17101 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    17161 aagatttgtt gaaagacact gttctgatcg gactaggaac gaatggctca ttctcggaag
    17221 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    17281 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    17341 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    17401 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    17461 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    17521 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    17581 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    17641 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    17701 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    17761 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    17821 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    17881 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    17941 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    18001 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    18061 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    18121 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    18181 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    18241 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    18301 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    18361 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    18421 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    18481 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    18541 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    18601 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    18661 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    18721 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    18781 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    18841 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    18901 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    18961 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    19021 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    19081 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    19141 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    19201 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    19261 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    19321 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    19381 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    19441 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    19501 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    19561 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    19621 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    19681 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    19741 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    19801 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    19861 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    19921 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    19981 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    20041 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    20101 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    20161 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    20221 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    20281 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    20341 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    20401 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    20461 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    20521 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    20581 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    20641 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    20701 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    20761 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    20821 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    20881 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    20941 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    21001 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    21061 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    21121 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    21181 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    21241 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    21301 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    21361 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    21421 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    21481 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    21541 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    21601 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    21661 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    21721 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    21781 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    21841 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    21901 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    21961 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    22021 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    22081 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    22141 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    22201 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    22261 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    22321 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    22381 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    22441 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    22501 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    22561 agcaagatgg ccaatgcaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    22621 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    22681 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    22741 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    22801 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttgat
    22861 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    22921 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    22981 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    23041 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    23101 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    23161 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    23221 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    23281 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    23341 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    23401 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    23461 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    23521 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    23581 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    23641 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    23701 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    23761 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    23821 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    23881 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    23941 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    24001 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    24061 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    24121 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    24181 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    24241 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    24301 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    24361 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    24421 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    24481 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    24541 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    24601 caaaacgatc aaggaataca attttccgat caaaacaaac ctttatcatt caaagtggaa
    24661 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    24721 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    24781 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    24841 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    24901 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    24961 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg cgaagtcatc
    25021 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    25081 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    25141 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    25201 ctatctgtct tccgtcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    25261 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    25321 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    25381 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    25441 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    25501 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    25561 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    25621 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    25681 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    25741 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    25801 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    25861 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    25921 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    25981 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    26041 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    26101 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    26161 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    26221 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    26281 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    26341 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    26401 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    26461 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    26521 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    26581 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    26641 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    26701 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    26761 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    26821 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    26881 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    26941 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    27001 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    27061 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    27121 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    27181 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    27241 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    27301 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    27361 ctttctcagc tagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    27421 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    27481 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    27541 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    27601 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    27661 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    27721 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    27781 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    27841 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    27901 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    27961 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    28021 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    28081 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga tttattttt
//
LOCUS       DADVXK010000026        27169 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.026, whole genome shotgun sequence.
ACCESSION   DADVXK010000026 DADVXK010000000
VERSION     DADVXK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.026"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(90..1058)
                     /locus_tag="KB909_001048"
     CDS             complement(90..1058)
                     /locus_tag="KB909_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBB6837098.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            1290..2123
                     /locus_tag="KB909_001049"
     CDS             1290..2123
                     /locus_tag="KB909_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBB6837099.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            2157..2996
                     /locus_tag="KB909_001050"
     CDS             2157..2996
                     /locus_tag="KB909_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6837100.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            3022..3582
                     /locus_tag="KB909_001051"
     CDS             3022..3582
                     /locus_tag="KB909_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6837101.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            3781..5502
                     /locus_tag="KB909_001052"
     CDS             3781..5502
                     /locus_tag="KB909_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBB6837102.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            5667..6809
                     /locus_tag="KB909_001053"
     CDS             5667..6809
                     /locus_tag="KB909_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6837103.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            6825..8036
                     /gene="thiI"
                     /locus_tag="KB909_001054"
     CDS             6825..8036
                     /gene="thiI"
                     /locus_tag="KB909_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBB6837104.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            8609..9256
                     /locus_tag="KB909_001055"
     CDS             8609..9256
                     /locus_tag="KB909_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6837105.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    9385..9601
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9649..12294
                     /locus_tag="KB909_001056"
     CDS             9649..12294
                     /locus_tag="KB909_001056"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBB6837106.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            12604..13917
                     /locus_tag="KB909_001057"
     CDS             12604..13917
                     /locus_tag="KB909_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBB6837107.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            13907..14560
                     /locus_tag="KB909_001058"
     CDS             13907..14560
                     /locus_tag="KB909_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6837108.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            14615..15307
                     /gene="radC"
                     /locus_tag="KB909_001059"
     CDS             14615..15307
                     /gene="radC"
                     /locus_tag="KB909_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBB6837109.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            15457..15657
                     /locus_tag="KB909_001060"
     CDS             15457..15657
                     /locus_tag="KB909_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6837110.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(15911..17590)
                     /locus_tag="KB909_001061"
     CDS             complement(15911..17590)
                     /locus_tag="KB909_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6837111.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(17592..17804)
                     /locus_tag="KB909_001062"
     CDS             complement(17592..17804)
                     /locus_tag="KB909_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBB6837112.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            18197..19927
                     /gene="efrA"
                     /locus_tag="KB909_001063"
     CDS             18197..19927
                     /gene="efrA"
                     /locus_tag="KB909_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBB6837113.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            19924..21684
                     /gene="efrB"
                     /locus_tag="KB909_001064"
     CDS             19924..21684
                     /gene="efrB"
                     /locus_tag="KB909_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBB6837114.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            21779..21976
                     /locus_tag="KB909_001065"
     CDS             21779..21976
                     /locus_tag="KB909_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837115.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            22129..22614
                     /locus_tag="KB909_001066"
     CDS             22129..22614
                     /locus_tag="KB909_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBB6837116.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(22718..23311)
                     /gene="clpP"
                     /locus_tag="KB909_001067"
     CDS             complement(22718..23311)
                     /gene="clpP"
                     /locus_tag="KB909_001067"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBB6837117.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            23491..24018
                     /locus_tag="KB909_001068"
     CDS             23491..24018
                     /locus_tag="KB909_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837118.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            24109..24846
                     /locus_tag="KB909_001069"
     CDS             24109..24846
                     /locus_tag="KB909_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6837119.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            24850..25767
                     /gene="miaA"
                     /locus_tag="KB909_001070"
     CDS             24850..25767
                     /gene="miaA"
                     /locus_tag="KB909_001070"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBB6837120.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            25769..26998
                     /gene="hflX"
                     /locus_tag="KB909_001071"
     CDS             25769..26998
                     /gene="hflX"
                     /locus_tag="KB909_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBB6837121.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(27032..>27169)
                     /locus_tag="KB909_001072"
     CDS             complement(27032..>27169)
                     /locus_tag="KB909_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6837122.1"
                     /translation="EFNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCL
                     A"
BASE COUNT         8948 a         4698 c         5813 g         7710 t
ORIGIN      
        1 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
       61 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
      121 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
      181 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
      241 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
      301 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
      361 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
      421 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
      481 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
      541 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
      601 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
      661 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
      721 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
      781 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
      841 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
      901 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
      961 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     1021 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     1081 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     1141 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     1201 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     1261 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     1321 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     1381 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     1441 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     1501 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     1561 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     1621 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     1681 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     1741 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     1801 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     1861 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     1921 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     1981 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     2041 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     2101 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     2161 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     2221 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     2281 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     2341 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     2401 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     2461 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     2521 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     2581 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     2641 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     2701 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     2761 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     2821 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     2881 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     2941 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     3001 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     3061 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     3121 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     3181 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     3241 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     3301 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     3361 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     3421 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     3481 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     3541 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     3601 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     3661 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     3721 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     3781 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     3841 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     3901 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     3961 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     4021 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     4081 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     4141 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     4201 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     4261 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     4321 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     4381 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     4441 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
     4501 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
     4561 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
     4621 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
     4681 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
     4741 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
     4801 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
     4861 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
     4921 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
     4981 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
     5041 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
     5101 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
     5161 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
     5221 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
     5281 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
     5341 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
     5401 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
     5461 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
     5521 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
     5581 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
     5641 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
     5701 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
     5761 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
     5821 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
     5881 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
     5941 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
     6001 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
     6061 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
     6121 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
     6181 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
     6241 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
     6301 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
     6361 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
     6421 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
     6481 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
     6541 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
     6601 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
     6661 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
     6721 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
     6781 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
     6841 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
     6901 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
     6961 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
     7021 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
     7081 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
     7141 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
     7201 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
     7261 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
     7321 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
     7381 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
     7441 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
     7501 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
     7561 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
     7621 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
     7681 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
     7741 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
     7801 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
     7861 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
     7921 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
     7981 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
     8041 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
     8101 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
     8161 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
     8221 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
     8281 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
     8341 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
     8401 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
     8461 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
     8521 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
     8581 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
     8641 aactgcgaaa agattacctt tatatttacg ctacttgaag ttgctggatg actcaggtat
     8701 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
     8761 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
     8821 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
     8881 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
     8941 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
     9001 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
     9061 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
     9121 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
     9181 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
     9241 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
     9301 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
     9361 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
     9421 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
     9481 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
     9541 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
     9601 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
     9661 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
     9721 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
     9781 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
     9841 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
     9901 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
     9961 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    10021 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    10081 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    10141 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    10201 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    10261 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    10321 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    10381 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    10441 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    10501 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    10561 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    10621 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    10681 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    10741 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    10801 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    10861 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    10921 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    10981 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    11041 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    11101 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    11161 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    11221 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    11281 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    11341 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    11401 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    11461 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    11521 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    11581 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    11641 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    11701 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    11761 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    11821 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    11881 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    11941 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    12001 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    12061 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    12121 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    12181 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    12241 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    12301 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    12361 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    12421 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    12481 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    12541 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    12601 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    12661 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    12721 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    12781 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    12841 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    12901 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    12961 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    13021 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    13081 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    13141 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    13201 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    13261 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    13321 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    13381 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    13441 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    13501 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    13561 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    13621 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    13681 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    13741 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    13801 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    13861 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    13921 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    13981 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    14041 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    14101 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    14161 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    14221 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    14281 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    14341 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    14401 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    14461 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    14521 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    14581 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    14641 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    14701 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    14761 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    14821 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    14881 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    14941 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    15001 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    15061 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    15121 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    15181 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    15241 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    15301 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    15361 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    15421 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    15481 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    15541 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    15601 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    15661 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    15721 aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt atgaaaaagt
    15781 aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga acaaacaaaa
    15841 atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg ctgatttcat
    15901 aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt ggatgtcttt
    15961 ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc aatttatatt
    16021 ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt cgctgagctt
    16081 cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga atatctggac
    16141 cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca agaccttctt
    16201 ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc ccgctaccat
    16261 cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg ctagttaacg
    16321 ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct acatcttgtg
    16381 ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata aaatattttg
    16441 gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg gaagtatgga
    16501 tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa ttgatcaaat
    16561 gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact gtatcgtctg
    16621 gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg gccatcgctt
    16681 ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga ttgatttcgt
    16741 gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga ccgttgacga
    16801 tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc acagcggcat
    16861 ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg atacgtcctt
    16921 cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat ttagtaaatg
    16981 ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct tccccgatac
    17041 gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat ttgaagtctc
    17101 cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca tctgggatac
    17161 tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc gtatcttcat
    17221 tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg tttgtgatca
    17281 acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc aagtagggta
    17341 ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact ttgtgtaagt
    17401 tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa tcgtcttccg
    17461 ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc ccatacgtat
    17521 ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta tttttgatgg
    17581 aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc gtactctaga
    17641 tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc ttccacacgt
    17701 tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc ttcccgttta
    17761 gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt gtctccttta
    17821 tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa cgaggggaca
    17881 agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa agagacaagc
    17941 ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat aaaaaatata
    18001 caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc aactagattg
    18061 aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt atgagagaag
    18121 tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta acaaaagatt
    18181 aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata agaaattctt
    18241 gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac ttcctacgat
    18301 tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg tgaagcaaca
    18361 agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct tgttaggtta
    18421 ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt tgttcgaaaa
    18481 gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat tgatcactcg
    18541 tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac gtatcggttt
    18601 tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa gtgtgacact
    18661 cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag cgattgctaa
    18721 ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca acagtatctt
    18781 gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa agtttgaaga
    18841 aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct tattccgttt
    18901 gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg tattgatcat
    18961 ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt tgattgcgtt
    19021 tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg tgttcatgat
    19081 gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg ccaaaccttc
    19141 gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata tcgaatttca
    19201 aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa atgtcagttt
    19261 tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg gaaaatctac
    19321 gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct tgatcgatgg
    19381 agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt ttattccgca
    19441 aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga aagaagatgc
    19501 tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat tcatttctcg
    19561 aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt caggtggaca
    19621 aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct atatttttga
    19681 tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc gtctgaaaaa
    19741 agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga tcatgcatgc
    19801 agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc atcgggagtt
    19861 gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa aggaggaatt
    19921 agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag accgtatcgt
    19981 gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa cgtggctttg
    20041 ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa tggcgaatca
    20101 atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg aatagggtat
    20161 tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag tgccatgcat
    20221 gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata tttcgataaa
    20281 aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt cagcggtgct
    20341 ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt ggctgcagca
    20401 atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat tccaacatcg
    20461 atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag catgcagaat
    20521 tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag tgtattgaaa
    20581 gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca cagcttgaaa
    20641 tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt tcaattaact
    20701 gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat tactggggcg
    20761 atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag tcagccaatg
    20821 gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac gaaacgtgta
    20881 ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc actgccagaa
    20941 acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc gaagaaacca
    21001 ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt ggtcggtccg
    21061 accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga cgtagacaaa
    21121 ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga tgtgcgttcg
    21181 ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc agataatatc
    21241 cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa aacagcaaac
    21301 gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa ttctgaggga
    21361 gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt ggtctccgat
    21421 cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt agaagcgttg
    21481 attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat cgctcaccgt
    21541 ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca gatcattgaa
    21601 aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact gtataacagc
    21661 caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa acttattttt
    21721 tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg acacggagat
    21781 ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc gtttaacgca
    21841 cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt ttcaaatcga
    21901 acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa tagaagaaaa
    21961 tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa atagacatct
    22021 ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct atgatacctt
    22081 tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat ggaacggttt
    22141 atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt gacgatctgg
    22201 tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag aacgaatatc
    22261 caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc ggagaatgtg
    22321 acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc gctgatcggg
    22381 atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat tggtgctgga
    22441 tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg tcgcccagct
    22501 aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa catccagcat
    22561 tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag ataggcagta
    22621 gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt tatttggttt
    22681 agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa gaactgtttt
    22741 ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata tagttgtcac
    22801 gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct aaaattttgt
    22861 ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca gttgcttgcc
    22921 cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa gcaaatcgtt
    22981 taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata cccataacaa
    23041 ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata cctgctgtaa
    23101 ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct tgagcgtcta
    23161 agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg ccgcttaaca
    23221 tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca cctcgtgaag
    23281 attgttcaat gactgtagga attaaattca taatagagtt cctccttgat ttcgtttaga
    23341 aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt ttggtcaaaa
    23401 aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg gtatgataag
    23461 cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg ccttatcgga
    23521 gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg tcacttggaa
    23581 aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga gacgctgaat
    23641 caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat ggaagaatat
    23701 gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc gtatctccaa
    23761 tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga gctatttaag
    23821 aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat tggtggatat
    23881 gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac tgaaatgatc
    23941 aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt cttctcgaaa
    24001 gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc gtggtaatgc
    24061 tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat gttacaaatc
    24121 tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc atttgcagaa
    24181 gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa agatggttat
    24241 ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg gctgattcga
    24301 gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag caaagaattt
    24361 ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca aaaaaattac
    24421 cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg tatcgaagaa
    24481 aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata ttgcagcttt
    24541 catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct ggacttattg
    24601 atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat agaaggagta
    24661 catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt tccaaaagca
    24721 attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga actcaaaata
    24781 gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc aacgaaaagt
    24841 aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg taaaacagcg
    24901 ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga ttcattgcaa
    24961 atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat gaataatgtt
    25021 ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc tgattttcag
    25081 cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc tatcatagct
    25141 ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg agcgacagaa
    25201 gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat tggttcccaa
    25261 gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat ccactggaac
    25321 aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca tagtatcacg
    25381 gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt agatacgaag
    25441 cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc agaaggttta
    25501 gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca aggtattgga
    25561 tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc aacagaacaa
    25621 gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg taaccgtttg
    25681 gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat tgagcaaaca
    25741 atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg taggggtaga
    25801 aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc agctgacgaa
    25861 taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag tggatcggca
    25921 aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg cgcatgaagc
    25981 ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga ttaccgatgc
    26041 tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg cgatgcgtgc
    26101 tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc tgctgcctcg
    26161 tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa caagagggcc
    26221 aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt ttgctgttaa
    26281 gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa gaaaaaatag
    26341 cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa ctatcttgaa
    26401 tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt tagatccatt
    26461 gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata ccgtcgggtt
    26521 catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag aagaaagtca
    26581 aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta ttttacagga
    26641 gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga tactgactgt
    26701 ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat tcccaaatgt
    26761 attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa tcaaacgtca
    26821 gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag gacagaaatt
    26881 aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag aaacaaacga
    26941 atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa accaataaaa
    27001 ttttattttt ttaacaatat tatttgtcaa attaagcgag acaaaacttt ccatttacgt
    27061 aactcaaaaa aacttctaat ggtgtttggt aatttagtga ttttctaggg atatggtttc
    27121 ttttggacgc aacggatgag atgaatcctt gattgacttg gttgaattc
//
LOCUS       DADVXK010000027        26766 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.027, whole genome shotgun sequence.
ACCESSION   DADVXK010000027 DADVXK010000000
VERSION     DADVXK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.027"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(26..1957)
                     /locus_tag="KB909_001073"
     CDS             complement(26..1957)
                     /locus_tag="KB909_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6837123.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="KB909_001074"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="KB909_001074"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6837124.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="KB909_001075"
     CDS             complement(2886..3638)
                     /locus_tag="KB909_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6837125.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3797..4006)
                     /locus_tag="KB909_001076"
     CDS             complement(3797..4006)
                     /locus_tag="KB909_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837126.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4017..5344)
                     /locus_tag="KB909_001077"
                     /pseudo
     CDS             complement(4017..5344)
                     /locus_tag="KB909_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5480..5635
                     /locus_tag="KB909_001078"
     CDS             5480..5635
                     /locus_tag="KB909_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837127.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5709..6296)
                     /locus_tag="KB909_001079"
     CDS             complement(5709..6296)
                     /locus_tag="KB909_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBB6837128.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="KB909_001080"
     CDS             complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="KB909_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBB6837129.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALSAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7876..9165)
                     /locus_tag="KB909_001081"
     CDS             complement(7876..9165)
                     /locus_tag="KB909_001081"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBB6837130.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9319..10251)
                     /locus_tag="KB909_001082"
     CDS             complement(9319..10251)
                     /locus_tag="KB909_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837131.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10408..11067)
                     /locus_tag="KB909_001083"
     CDS             complement(10408..11067)
                     /locus_tag="KB909_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6837132.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="KB909_001084"
     CDS             complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="KB909_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBB6837133.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12108..12398)
                     /locus_tag="KB909_001085"
     CDS             complement(12108..12398)
                     /locus_tag="KB909_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837134.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12807..14612
                     /gene="glmS"
                     /locus_tag="KB909_001086"
     CDS             12807..14612
                     /gene="glmS"
                     /locus_tag="KB909_001086"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBB6837135.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14684..16039)
                     /locus_tag="KB909_001087"
     CDS             complement(14684..16039)
                     /locus_tag="KB909_001087"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBB6837136.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16063..17232)
                     /locus_tag="KB909_001088"
     CDS             complement(16063..17232)
                     /locus_tag="KB909_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837137.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17229..18116)
                     /locus_tag="KB909_001089"
     CDS             complement(17229..18116)
                     /locus_tag="KB909_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBB6837138.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="KB909_001090"
     CDS             complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="KB909_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBB6837139.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22196..22717
                     /locus_tag="KB909_001091"
     CDS             22196..22717
                     /locus_tag="KB909_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6837140.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(23416..23973)
                     /locus_tag="KB909_001092"
     CDS             complement(23416..23973)
                     /locus_tag="KB909_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837141.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(24152..24763)
                     /locus_tag="KB909_001093"
     CDS             complement(24152..24763)
                     /locus_tag="KB909_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837142.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(24876..25133)
                     /locus_tag="KB909_001094"
     CDS             complement(24876..25133)
                     /locus_tag="KB909_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837143.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(25730..26008)
                     /locus_tag="KB909_001095"
     CDS             complement(25730..26008)
                     /locus_tag="KB909_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837144.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(26042..26293)
                     /locus_tag="KB909_001096"
     CDS             complement(26042..26293)
                     /locus_tag="KB909_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837145.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         7558 a         5767 c         4584 g         8857 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga ctggtttttt atttttttgt
     3781 ctatcatcaa gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag
     3841 aagcaggttt tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga
     3901 ccaaaaaacc gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata
     3961 ataatgatgc cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat
     4021 attttttgta aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga
     4081 tgctgctcac ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg
     4141 aaggtaacat cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct
     4201 gaaggaacat agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct
     4261 acttctagat attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca
     4321 gtcggatcga taactttata gcacatcatg cgtgatcgat tctcgtcaac ccaaggaaaa
     4381 tacgcctgag catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttggata
     4441 tcataacttt ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca
     4501 ttctgatact ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt
     4561 ttcaataaac cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa
     4621 taggattgaa acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg
     4681 atacatatga cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa
     4741 atcggtttag ggatgatttg atgataatag cgactataat acatttccca acacgaagtg
     4801 aaacataaac cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact
     4861 tccccgtttt gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat
     4921 agccgttgag agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag
     4981 gcgaacaccc catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt
     5041 tctttgaaaa cagagataga caatacattt tttatcaata attgattatc ttccaagcga
     5101 aaactacatt cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct
     5161 agcattattt tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag
     5221 cggataaatg ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt
     5281 ttttttcttc ttcatttaag tctgtgagct ggatagtcat caataattta tcttcgccaa
     5341 tcattttctc acctctttca aatcttttta taatttaatt ataaccaatg ataaagaaaa
     5401 actaaaactt tatgtcttag aaaccaattt ggacgattac atgatagact aagtaaaaag
     5461 aaacaaagag gtgtttacaa tggggttgaa atttgaacgt acagataatt tagataaact
     5521 tttcgaatca tttgctgtcg atccggaaaa aacagttgca ccaaaagaag agatcgatcg
     5581 atttctaaaa ccacagccac aaaatgaaaa gaaaaaagac aagaaacaaa agtaagttaa
     5641 gctcaaaaaa agacttacca gccaaacttt tatgaaagag tttgactggt aagtcttttt
     5701 tattcttttt atgattcaat tgcttgttcg attgctgccc acgcttcttc ttttccctgt
     5761 tttgtaacgg aagaaaagag aataaacgtg tcattgcgat caaaatccaa cgcttttttg
     5821 atttcgctct catgcttgtt ccatttacca cgagggatct tatctgcctt agtggcaaca
     5881 acaattacag ggatatcata atacttcaaa aattgataca tctggatatc ttcttgagaa
     5941 ggcttatgac gcaaatctac taaagaaacg accgcacgta gctggtctct agtcgttaaa
     6001 tatgtctcga tcatctttcc ccattttgct cgctcagttt tggatacttt tgcataccca
     6061 tatcccggaa catcgacaaa atgtaatgcg ttctcgatca aataaaaatt caatgtctgg
     6121 gtctttcctg gcttaccgga agtacgggct aaattctttc gatcaatcaa tgtgttgata
     6181 aaagaagatt tccctacatt tgatcgtcct gccagagcta tttctggcaa ttgtgtatct
     6241 ggatattgtt ttggtgccac tgcacttatg ataatttcag cttgatggac tttcatggtc
     6301 tctctcctta acaaggtgat gaataaagca agcggctgtc gcaaaagcca aaatgacttt
     6361 tacggcagcc tcttttcatc aacccgcttt tttctctgaa tctttataga ttactgttgg
     6421 ctcaccagac aattcagctg cttcttttgt gataatcact ttttcgatgt tttcatttga
     6481 agggatatca aacatcacat ccatcatgat ttcttcaatg atggaacgaa gtcctcgagc
     6541 accggtattg cgttcgattg cttttttcgc aatggcactc aacgcttcag gttcgaattc
     6601 aagttcggta ttatctagag aaagaagttt ttgatattgt ttgactagcg catttttcgg
     6661 ctcagtcaag atccgtacca gatcatctgt tgtcaatttc tctaaagctg ccataacagg
     6721 taatcgtccg ataaactcag ggatcaatcc gaattttagt aaatcttcag gaatgatatg
     6781 ctgcatgaca ctttcgtctt cagaaagttt ttggttttgt gtaccaaatc caatcgtctt
     6841 ttcgcccata cgattcttca caatcgtttc gatgccatca aatgcaccac ctacgatgaa
     6901 caatatgttc gtcgtatcaa tctgaataaa ttcttgatgt ggatgtttac gtccgccctg
     6961 aggtggcaca cttgcaacag ttccttctag aattttcagc aaggcttgtt ggacaccttc
     7021 gccggaaacg tcacgagtaa tagatacatt ttcgctttta cgcgcaattt tatcgatctc
     7081 atcaatatag atgatccctt tttctgcaag ttccacattg taatcagcag attgaagcaa
     7141 tttaagcaaa atgttttcta catcttcccc cacataacca gcttctgtca aacttgtcgc
     7201 atctgcgatt gcaaaaggta cattcaatgt ttttgctaat gtttgtgcta aaaatgtttt
     7261 accagaccct gtaggtccga tcaagcagat attgcttttt tgcagttcaa catcatctgt
     7321 gttttcttgt gcttgctgat tgacacgttt atagtgattg tatacggcaa cagctaacga
     7381 gcgttttgcg cgatcttgtc caatcacgta gttattcaat acttcaagaa tttctagtgg
     7441 tttagggact tcagtgaatt cgcgtacagc ttcttcataa aattcttcat caatgatttc
     7501 tttacatagg tcgatacatt cattacagat gtagacccct ggaccagcta cgatcttttt
     7561 cacttcttct tgggttttcc cgcaaaaaga acagcgtacg gtctcattgc tacttggatt
     7621 gtcatacatg gtcttcaccc cttaacttgc aaaaagtatg caagaaacta tcaaagactt
     7681 tacagtcttt tactatcata acatagttta gtaaaaagaa aaagtgttta acaaaggatc
     7741 aactgaccta tacctttgca ttttttactc ttaacaaaaa ataaggaact gtgacaaaat
     7801 cgtgtcacag tcccttattt cgaataaaca attttctaga agtagcttct tcagaaatga
     7861 tttattactt gatttctatt ctttcgcttc tgtcgctgta cctgtgatca attcgattgc
     7921 ttttttcatt gtcacatcat gttccagcat atcttctgtc aacacgcgtt tgatttgttc
     7981 gattggcatg ttgtatgttt ctgataattc ttggatttct gcattgattt cttcttctgt
     8041 tgcttgaaga ttttcagcag ctgcaattgc ttcgatcaca agatttgttc ttgtgcgcat
     8101 ttctgcttca ccttcgaatt gtttatgcaa gtcttcttct gtagaaccag ttaattgata
     8161 gtacatttca ggagagatac cttgacgttg catgttgttc aagaattcgt ccattgaacg
     8221 atgtacttca tcatgaacca tcacgtgtgg caattcaacg atttctgcgt tttcaacagc
     8281 catacggatc gctgcttcat cttttgcatc gtccgctgct ttttcttttg tttctactaa
     8341 ttctttgcga tatttttctt tcaattcgtc taatgttgat acttcgtcat caacatcttt
     8401 tgcgaattcg tcatctaatt caggcacttc ttttgctttt acttcatgga ttgtcacttt
     8461 gaagactgct tcttttccag caagatcttc tgcttgataa tcttctggga aagttacatt
     8521 tacatctaga ctttcacctg atttatgacc aactaattga tcttcaaaac ctggaatgaa
     8581 tgagcctgaa cctaattcaa gtgagtaatt ttcgcctttt ccgccatcaa acgcttcgcc
     8641 atctacaaag ccttcgaagt cgattactac tgtatcgcca ttttcagctg cagcatcttc
     8701 tttgataact aattcagctt gtgcttcttg ttcacgtttg atacgtgcat ccacgtcagc
     8761 atctgttact tcacggtctt gtttttcaac aactagatct ttatattgtc ctaattttac
     8821 ttctggtttc actgttactt cagcagtgat tacccagtct tgaccttttt ccatgctttc
     8881 aacatcgatt tttggttgag aaacaggatc gatgccagct tctttgacag cagcttcata
     8941 agcttctggt aatacagcat tcaatgcatc ttcatataaa gcttcttcac cgtacatacg
     9001 gttgaatact tgacgagaaa ctttcccttt acggaatcca ggtacgttca agcttttttt
     9061 cactttatta aacgcagttg ttaatccttt ttggatttcg tcttgcgcaa tcgtaaattt
     9121 taaaacacca tcattcgtgc cttttttttc aaatgttgca gtcatttaat tccctccgag
     9181 tttagaaatt cattttatac atcaaaaacg tttcatgcat acctttaaat agtacactaa
     9241 ccctttcaaa ttgtaaacat attgaatgga tagaatcctt gtttttcata acatttttat
     9301 ctttttcact gataaaatct aatggaagaa gatcatttgc tgcaaaattt tttctctttt
     9361 ttttaaaaaa tcttgttttt catcttctgt accttcatac atcgtttttc ctgtacacgc
     9421 ctctacagtc agttgaaacc agcgcttcgg gtcttcgatg tatgtatcat agacaggata
     9481 aacaattgca gattgcaacg tgaattcttc ttttaacacg gaactaagca gcgcatcttc
     9541 attcccgtaa cgatctgaaa atacacataa ttgctggtaa cttgcctgct gctgcggctt
     9601 tggcagatct tttggtatga ctttgactaa cttttcttca atcgtcaaat agaaaacagg
     9661 atggcattcg ttcaattgcc taagtgtctc cagtaatttt gcccttgcta aaatatggac
     9721 ctctggcgat acaataagtt tactcgctgt ttggataaac tcatgataag gaagctgttc
     9781 gatctcatca atagacgcaa gctgacgtgc aggttccaac gaaggaagtt cctccgattt
     9841 attgtggagt gccttgatct tctgcctctc catttgtccg gataattctt ctgcaaattg
     9901 gattttttca atgacccgct gctcgaaagc ttcataaaaa tctgtacttg ctatcaattt
     9961 tctagcatat aaaaaatctt gtgtactgat taacaagtca aaataaaatt cagcaaactc
    10021 ctcattttga agatactgtt tttcatgcaa gagtgcttgc ttcaatgctt cttttttctc
    10081 gtccaactcg taaagacaaa aaacaagcag gctattagcc tcaaagcttt ctttcaactc
    10141 gtaagctcgt tgaaataatt cttttgcctg ctgatattgc tggtttgcta gtgcttgttg
    10201 tgccactcgc attaaattct catatttttc tggaaaatca atcggcttca cgcagtgtcc
    10261 tcctcttgct catattcagc tcatgttcaa tagtagcaaa acaaaaaaag catgacaatt
    10321 aaaaataact gaagcaccct ctaaaagcta gattttagat ctgactttta gaaggtgctt
    10381 tcaactgtta ctgcttttta ttgctcatca gctgttgact tcctggttga acgctttgat
    10441 cagattgatc gtaacaacac ttgtattagt gaaaaaatcg cccagatgtt gctttttctg
    10501 attaaagact gctggaagat accctaacat cagcaaagga aattttagaa tgaaccggca
    10561 agcaccttct ctaactaaaa cggttgacca gctaagttct tcttcatcaa agctgatgac
    10621 tcgaatacca aagatcattt tcccaatcgt ttggccatga ttgaatttcg tcaataaaat
    10681 aaaatacgct agataaataa gtaaggctgt gaatccgtag agactcagat aagaatctga
    10741 aaaattaagc caacctagat ttttggcaat accaagtgtt aaacgcgtaa tagctccgat
    10801 acacaaaaga tcgaccaaga aggcaaacat tcggataaaa aaacctgcat agaaatactt
    10861 aggaaaatca tttgcttttg gcggttcatt tcttgtgtcc gtatactttt tccatttacg
    10921 ttgtttcttt ttgatttctt cgggcgtcaa aggctctctt tcaaaagagc tcagtacctt
    10981 ttgggaaaag ttggagtcag gtcctacagc aggctgctgt tgcttatctt tttcttgttc
    11041 cttattttca tttgaaagct ctgacatgct tactcacctc cgtaataata cattgctttt
    11101 ggtgattccg ctgtccctag attctcaaga acggataaga tctgactagt ctcagaaggc
    11161 ttcaatccct ggaattctgc tagtttactt cctaaccatg tactagcaaa cccagatggc
    11221 gtggaagaat attctactag ttccgcatct tcaagctgtt gttcctttcg tatagctttt
    11281 aaagcatctt caggaaatcc caattcatcg actaaaccta cttcttttgc ttggacacca
    11341 tcataaatcc ttccatcagc aatttttttg acttcttctt cagatttatt ccgtccctcg
    11401 ctgacgattg ctacaaaacg actatatgcg ctgtcgatat atgcttgaag caccgcttct
    11461 tcttcttttg tctctggtcg cgttcctgaa cccatatctt tcaacgctcc gcttttaact
    11521 gttgtatctt ccacacccag tttttctaga agtcctgaat aattcaatcc tgacatgatc
    11581 acaccaattg agccggtcac tgtttcttct gttgcaaaga ttttatctgc ttgagcagaa
    11641 atatagtagc caccgctagc tgccatgttt ttcatgctga catacattgg gatatcatgt
    11701 tctttacgaa tcgtatccaa tttcttagcg atttccgcac tttcgtagac accgccacca
    11761 ggagaattta cttctaaaaa gatacctttg actgttggat cttcttcaat cgccttcagt
    11821 tgttccataa aatttttatg attgtaacct tcagaagcaa ataaacctga agaccctccc
    11881 gcagcaatcg ttccatctac tgataatttt acgatttttt gcgtactgtc tccctcttcc
    11941 aacacatttg gagctagttc ttcatcccca tataaccaac tgttcaatcc ctcaatttga
    12001 tcgttttcct gaggcttagt caaactagct gaaactaacg aaaccacaaa taatcctgca
    12061 gcaatcagaa ctgctgccca acgtctttta ttcattcttt ctcctttcta atacaagttt
    12121 tttatgacga tcacagtttc tgactgctca gaagtgtcga accgctctgc tttttcttcc
    12181 cgcgcatacc cggaaaacga ctcttttgtt aattcatctt ctaccgtaaa ctcacgagct
    12241 tgagcaactt ccaaggcatc aggtgcgatt tcttggatgc tatcccagcc agtatctaaa
    12301 aatattttcg tatcatctga tacaccagct gatgcttcga atttggacaa ttgttttttt
    12361 aacattccca gtgtcatgat ctcaattttt gaatccattt ttactcctcc tctatccgat
    12421 tactttctat tgtaccgaac tcctgaaaaa gatgatagat aaaaacccat tattttttga
    12481 cataaaaagg acatttgaca aagaatttga tatataccaa tttatttttt attctttttt
    12541 tgttgacaag aacattcgca aaaggttatg attttaaatg tttccagata aaaaacaaaa
    12601 aggaggatag ttataccttt taggatagcg ccaggtctgt gtaaacagat gacgaggaga
    12661 gggtttatcg aaagattcgg cggatggccc tagggactgc actctacaga aaatccacaa
    12721 aaaatgtctg caaagataaa acaaaaggat tttcctgcag ctggaagcat tcatacgaat
    12781 tcattataga aagtaggatg ttttttatgt gcggaattgt tggaatgatt ggattaaaaa
    12841 atgtaacacc aggattgatt gacggtctag aaaaattaga ataccgtggt tatgattcag
    12901 ctggtatctt tgtctcagat ggcacaactg attatctggt caaagcacaa ggcagaattc
    12961 aaaatttgaa aaacaaaata aatattgata ctacaggaaa tataggtatt ggtcatacac
    13021 gatgggcaac tcacgggcaa ccttctgaag aaaacgccca tccacatact tcccaaagtg
    13081 gacgcttcgt gctcgttcac aacggcgtaa tcgaaaactt tgaagaactt aaaattgctt
    13141 atttagcaaa tgaccacttt attggtgaga ccgatactga gattatcgct catctaattg
    13201 aaactttcgc gaaggatact acaacgcaag aggcgttttt aaaagctttg cgggtcatca
    13261 aaggttctta cgctttcgct ttgattgatc ggacagcacc tgatgttatt tacgtcgcta
    13321 aaaataaaag tccactatta atcggactcg gcgatggatt caatgtgatt gccagcgatg
    13381 caatggctat gcttgctcat acgaaggaat tcgttgagat tgaagatgaa gagatggtta
    13441 ccgtcacatc agaaaaagtt attattcaaa attttgcagg tgacatcgta gaacgttctt
    13501 cattcgaagc acaagtagat gcttcagata tcgagaaagg tacctatcct ttttatatgc
    13561 tgaaagaaat cgacgaacag cctattatca tgcgtcgtat cgctcaaaaa tacgtaacag
    13621 aagacaatcg tgtctctctt gatcaaaagc tggtcgatac attgtctgat agcgatcgaa
    13681 tctatatcgt tgcttgcgga actagttacc atgcggggtt agcaggtaaa cagactttgg
    13741 aaaaattgac acagattcct gttgaggttc atttagccag tgaatttggc tataacacac
    13801 ctcttctttc aaaaaaacca ttctttattt tcttgagtca aagtggcgaa acagcagaca
    13861 gccgccaagt gctggtaaaa atcaaccgtc tcggctaccc ttcacttacg attacaaatg
    13921 ttgctggttc tactctttcg cgggaagcat cctttacact gctattgcat gctggacccg
    13981 aaatcgcagt agcatcaacg aaagcttata ctgcacaaat agctgtacta actttattag
    14041 ccaaagctat cggtgataaa aaagaatttg aaacttctct tgtattcgat atcactcatg
    14101 aattgagttt agttgctaat gcgatggaat cggtcatcgc ccaaaaagat tatttagaag
    14161 agttggcaga agtatatctc agcgatacaa gaaatgcctt ttacattgga cgtggtgctg
    14221 actacaacgt ttctcttgaa gctgctttga aattgaaaga aatcagttat atccaggcag
    14281 aaggttttgc cgctggcgaa ttgaaacatg gaacgattgc tttgatcgaa gaaggaacac
    14341 cagtgatcgg aatcatcagt gaagaagtga ctggtgcgca tactcgagga aacctgaaag
    14401 aagtcgaaag ccgtggcgct aaaacactag ttattgtctc agagggatta gaaaaggaaa
    14461 gtgaccagct ggtgctacca actgtccacc cttatctaac tactctaacc acagtcgtac
    14521 cgactcaatt acttgcatat tacgcaacgc tattacgggg attcgacgtt gacaaaccac
    14581 gtaatttagc gaaatcagtg acagtagaat aataaaagaa caaggaccag tgtcagacat
    14641 ctgacactgg tccttgttct tttatttttt atgaaaatat ctcttaatcc agtccgattt
    14701 cttctttgac tactgccgcg attttatcga catagtaatt aactttctca tcagtaggcg
    14761 cttctgccat cactcgaagt aatggttctg taccggaagg acgaactagg attcttcctt
    14821 ctgatcccat ttcagcttct gcctcttcaa tcactttttt gattgccgga acatccatcg
    14881 caccgttttt atcacttacg cggatattca ctaatttttg cggatagatt gttacctctg
    14941 ctgcaagctc tgataatttc ttacctgtct gtttcatgat attcagtaac tgaattcctg
    15001 aaagcatccc atctccagtt gtgttaaaat ctaagaaaat catgtgccca gactgctcgc
    15061 cgccaaagtt ataatcgttt ttgcgcattt cttctacaac gtaacgatca ccaacttgtg
    15121 taacgacatc tttcaaaccg attccttcca ccgctttgtg gaatcctaag ttactcatga
    15181 cagtcgtaac gatcgtatct tttttcaatc gatttttttc tgccaagtat ttagcacaga
    15241 taaacatgat tttatcaccg tcgacaatgt ttccaagttc atccaccgca ataatacgat
    15301 cgccatcgcc atcgaaagct agtccagcat ctgctccttt ttcaacgacc atctcagcta
    15361 aacgttctgg atgggtagag cctacgccgt cattgatatt taacccgtct ggatttgtgc
    15421 ccattgtata aaaatctgtt tcaagatcgg caaacaaacg attaacactt gttgaagttg
    15481 ctccgtttgc tgcatcgaca caaatggtca aaccggaaag gtcaccgttg atcgtttgta
    15541 caaggaattg agaatatttc aataagcctt ctggaaattc ttctacagtt cccaatcctt
    15601 cagctgatgg acgaggcaat tcatccactt cagcatctaa taatgcttca atttctagct
    15661 cttggtcatc tactagttta aaaccatctg caccgaaaaa tttgattcca ttatcttgtg
    15721 ctggattatg agaagcagaa atcatgaccc ctgcgcttgc tttttgcaaa cgtgtcagat
    15781 aagcaacacc tggtgtagag atcacaccta gctggaacac ttcgataccc accgataaaa
    15841 gtcctgaaat cagcgcttct tctaacattt gacctgagat tcttgtatcc cgccctacta
    15901 acacgcgtgg gcgttttcct tcttcttcat gctggcttag gacataacct ccgcaccgtc
    15961 ccagcttaaa tgcaagttct ggcgtaagtt ccttgttggc ttcaccgcgt acgccgtctg
    16021 ttccaaaata tttacccata gttgtaaaat tactccttta acttaatttt ctgaggaatt
    16081 tgttctgctc atttgtgttg attcgcttgt ttctgatgtt tcttctgtac ttgtggtcga
    16141 gctgcttgtc ccagattccg aactggaaga aatggttgtt gtcgatggtt ccgttcctga
    16201 atcagcagat gaaatacttc tactcgtact tgtattttct tgtgtccgac tgctcgtcga
    16261 agcagagcta ctgcttgacg tttgcaacac gggtgtaatc tccacactaa ctgattcggg
    16321 cttgatactt aacccctctt ctactggtat ttcaatttta cgagttgttc gatgattgat
    16381 acctgagaca ttgatcggta cagcaatact gtcaccgatc gatgcaagca aatcgctaga
    16441 gccgcttact tctgcttcca gttttgaaaa actgaaatca tagctttcta ccccggcagc
    16501 tggtgttcct tgctgtatcc cataaagtcg taccgacttg cttggcttga tcgaatcagc
    16561 tctcactgtt acttgcactg gatcagagac gatacttaat acttcccctg ctgcattcag
    16621 cgcctgtatt gggacctcac tattaatccc atcatctgtg accatcgaag cgtccacatc
    16681 agctactact cgtttgattt ctgccaatgt tttgtcacct gtagtgatag agactttttt
    16741 aggactaacg gaagtatcat caagttcata tccagatggt gtgaacgttg aaggaatcaa
    16801 cgtttccaca tcgaaatctt ttattacctt tttctcaacc gttactgtaa tagtcgatgg
    16861 ttcgatcttt gctgtgacag cactgctcaa attttgaatt tttagcggaa cttcatgtgt
    16921 tccttcgccc agcttagtga tatctgctgt gacgcggaac atccgtgtat cttcgtttgc
    16981 ctctgcattc aactgaactc ggtttgcact ggaaagtttg acagtcactg cattttcata
    17041 tccatggata tagtagcgct ttgaatcata agaaatcttg atcggcaccc ccgtaactgt
    17101 ttgattatac gcttcatttc cagaaagcgt atttggaacg gactggccat ttgcattgaa
    17161 gtacagcgca atactgaaca gcaatgcaat aaaactgtaa agaatgcttg tccgtttctc
    17221 ttttgagatc atttgcgatc ccctccctta gtcataccgt ctaggaaaga ttgaatcacg
    17281 tttttcttgt tttttgtttt ctcttcagca attagttctc tacgcaagat tgccaaatat
    17341 tcttgctggg ataagccagc catcagttca ttatctaacg tgatgctgac gtccccggtt
    17401 tcttcagaga caacgatggt aatcgcgtca ctgacttcgc ttataccgac agctgcccgg
    17461 tgtcgagtcc cgaattcttt agggatcaac atactttctg atagaggaag ataggcgctt
    17521 gctactgcga tctttccttc ttttacaata actgcaccgt catgcagcgg tgtattagga
    17581 ataaagatat tgatcagcag ctccccagtg atatctgcat ctaaagcaat ccctgtctca
    17641 atatactcat ctaatccagt atgacgttcg atagtgatca acgcaccgat ttttcgcttg
    17701 gacatatatt ggatggcttt gtcaaaagac aagatcatct tctcatcttc ctgctgttcg
    17761 ctttttgatt gtttgaaaag cgaactgcgt ccaagatgtt ccagtcctct ccggatttcc
    17821 ggctgaaaaa tcacgatagc agctatcacc ccgtacgtaa tgacttggtt catcagccaa
    17881 gacaaggtgt gcagaccaat gatttccgct acgattcgga taacaataaa aatagctaca
    17941 cctttcagaa gctgaatcgc ttttgtgcct cgcagcagtt ggatcagttt gtatacaaga
    18001 taccagacaa ccagaatatc aagtatgttc accaaaaaat tcagagagaa caagtcaccg
    18061 gaaaacattt gctgccaata gtccaaatta aaaagttccc cgatttgaaa tgacataaaa
    18121 agcctctctt ctcttttgag atttcctctc tagtatatca tatgttttaa ttttagaggc
    18181 tgatatgctc gtatttttct tgagaaaaac gcataatttt caagaaaatt gcaagtatgc
    18241 gttttatttt tctctgcaat aaatattttt aaacttcaga gaattattca ttatattttt
    18301 tctgttattt ttcctttttt tcttttgtag cttgttccat ttttttacgt cgttctgctc
    18361 tggcagctct tctagcagct cttctttctt ctgcttcaag gtccgtcgtt ttttcttttc
    18421 tagtcttaac gggtacatcg atagattcct ctggttcaag tcgtttcttg attttttcta
    18481 attctcccgt cagtgcagca tagttgtaaa aacgtgtttt agcgtcgtgg acagtctttt
    18541 caaataaagc ttttgcaaga tttggatttg cgttatctag cgaggaaaag cgaacttgtt
    18601 tcctcatgaa atcaggcata gcagagaaat caggtttttt gtagtccaaa gtcattgggt
    18661 tcttgttttt ttcgaccatt gtagggttat atcgatataa tgaccaataa ccagaagaaa
    18721 cagcttcttt tgcttcttta agcgattctt tcattccgcc aagcaagcca tgtgtgatac
    18781 aaggcgtata ggcaataatc agagaaggac caggatactt ttctgcttct tcaaatgcct
    18841 tgatcgtttg catttgattg gcacctgaag caatttgcgc cacataaaca tttccatatg
    18901 tcatcgccat cattcctaga tctttctttg aagcatactt tccactagcc gaaaatttag
    18961 cgattgccga agctggtgtt gcttttgagg tttgaccgcc agtattggaa tagacttcgt
    19021 tatccaaaac aaggatattc acgtctgctc cgctggcaag tacatgatcg atcccgccaa
    19081 aaccaatgtc gtaagcccat ccgtctccac caatcatcca ttggctgttt tttacgaata
    19141 gatcctttct cttgtatata tcctccagtt cagggaaaat tgatcgttcg ctttcgatcg
    19201 cagcttgcag ttttgctgct ctttgctgcg ttccttcact ctcaaacatg tgtactaacc
    19261 agtcttccat caattctcgt agttcttctg atacttttgg caatacttct ttgattgaac
    19321 ttgccaaagc ctcgcgacga gtctgtgccg ctagaagcat accataacca aattcagcat
    19381 tatcttccaa taaagaattt gaccatgcag gcccttgacc acattcattg gtcgtataag
    19441 gagaagcagg agaagcaccg ccccaaatag aagaacagcc tgtcgcattc gcgatcatca
    19501 ttcgatcacc gaacatttgt gtcaataatt ttacataagg tgtttcgcca cagcctgagc
    19561 aagcgcccga gaattcaaga agcggttgat tgaattgtgt agacaagaca gtattctttc
    19621 ctttgactgg atttgctttt tgtcttaatg tcattgcaaa agcccaattc acagcttgtt
    19681 ctttctgttc ttcataaggc ttcatcacta aagctttttc ttttgcggga caagcctcta
    19741 cacacagacc acaacctgta cagtcttcca ctgaaacttg gatacggtat tttacgccgt
    19801 ctgcgcctcg catttctctc acgataaatc cttctggcgc ttcttccatt tcctcttcat
    19861 ctgctaaaaa tggacggatg gcagcatgag gacaaacaaa ggcacattca ttacacatcg
    19921 tacagcgatc actaatccac tcaggtactt ctaaagcgac gccccgcttt tccatagaag
    19981 ccgttcctaa aggcatttcg ccagttgtca ttccatttgc tacaagtgta ccaacagaga
    20041 gttgatttcc ttcctgtgca ttcactggtt caagtatttc ttgtatataa ccagtgttcc
    20101 ttttattgat tttttcaggc atctccaacg ttctccaatg gtctgggatc gcgacttgat
    20161 gaagcagttc ggtcgtccga tcgattgctt gtatgttttt ttctacgata gccattgatt
    20221 tatgtccata gcttttcagg gcttcttctt ttagcagcgg aagcacctca tcaaaaggaa
    20281 tgatgtcagc taatttaaaa aaagccgttt ccattgccgt attgatccgg cgtcccaaac
    20341 cgacttcttg ggccaatctc atggcattga tcgtatagaa tctaatgtta ttttcagcca
    20401 agtaacgttt taattttaag ggcagatgcg tttctaattg ttcgtcgctc caaagagtat
    20461 tcaataaaaa aatgccacct ggcttcaatc ctttgaccaa gtcatagcta tgcaggtaag
    20521 ctggtgtgtg acaggcaaca aggtccgcat gctcgacaag atacgctgaa cgtatcggcg
    20581 tatctccaaa acgaagatga gagacagtca gaccgccaga ttttttcgaa tcataataaa
    20641 aatagccttg cgcatattta tcggtgtgat ctccaataat cttgatagct gatttatttg
    20701 ctccaactgt tccgtcagat ccaaatcccc aaaacttggc ctggaatgtt tgcggttctg
    20761 tcaaatccag actttccttt ggttccaaag attgataagt cacatcatcc acgatcccta
    20821 tggtaaaccg ttttttgcgt atgcttgggt cttttttcaa ttcatcaaaa actgctgaga
    20881 tttggtcggg agtcacatct ttagacccca atccgtagcg accaccaata acagccgggc
    20941 gaagttcaga atcatataac gcactttgaa cgtctaataa gagaggttct ccacctgccc
    21001 ctggttcttt acttcgatca agaacagcaa ttgtttttac tgtatgaggc aacttttgca
    21061 cgaatgtttc cactggaaaa ggacgataaa gatggatatt caaaaaacct gttttccgtc
    21121 cgtttgcatt caagtaatca atcgtttgtt caatcgtctg tgcaactgat cccatagaaa
    21181 caatgacttc ttccgcatcg tctgctccgt aataagtcac caagtcataa gaagttcctc
    21241 gtaatcggtt gatctctttc atatattttt gaacgatttc aggtaattta tcataatagg
    21301 ggttgatcgt ttcccgttgt tgaaaatgga tgtctggatt ctggttcgta ccactaacag
    21361 tcggatgatt gggattcatc cctcgtttac gaaatgaagc taatttctcc tgattgatca
    21421 gaggagctaa ttcttcatat tccaaaactt cgattttttg aatctcgtga ctcgtacgga
    21481 atccatcaaa gaaattcaaa aaagggactt ctccttcaat agaagcaaga tgggcaacag
    21541 gtgctaaatc catcacttct tgtacactgc tttcagctaa catagcaaat cctgtttgtc
    21601 ttgcagccat cacgtctccg tgatctccga aaatattcaa cgcatttgtc gtcactgccc
    21661 gactagcaac gtggaaaaca cttggcagta gttccccagc aatcttgtac atattcggta
    21721 tcatcaaaag cagcccttgt gaagcggtat atgtagttgt cagtgcacca gttttcaatg
    21781 atccatggac cacaccagct gctcctgctt cggattgcat ttctactact tttactggtt
    21841 gaccgaatac gttttctttt cctgctgctg accattgatc tactaattca gccatggtcg
    21901 aactgggtgt tattggatat attgcagcaa tctcggtaaa tgcataagaa atatatgcgg
    21961 ctgccgtatt gccatccatt gttttcattt ttcgcatgat tcatcatcct tgttcatatt
    22021 ctctcttatt atctgttcca ttataacgta aaacatgcca tttttttctt ttatttataa
    22081 aaatatttta catgtatcta tttgaattgg tcatctaatt tttagacaaa cagtctaaat
    22141 cgttgccttt ttttgtcaga catgtataaa ctataagcga aagaggtgtt ttaacatgga
    22201 tatatcagtg attgatgcaa cgaaaacaaa tacacaaaaa ggaatccttt atggttcatc
    22261 gaatgctcct aaaaaaatgg tcgaattcat caacttagct tgtccgtatt gccgacaatg
    22321 gtttgaagaa tcttatgagc tattagaaga agcagtccaa agcgggcaat tgcagcgagt
    22381 gatcaaattg ttcgataaag aaaaagaaag cttacagcga gggaacgtga tgcaccggta
    22441 tctcacaatc agcgatggcc aaaaagcgat caaagagatc aaacaaatat tcgatactca
    22501 agacgagtgg aaacatcttt ctctccaaga agtagcggat tttgcagtag ataaactaaa
    22561 gctgacagaa caaaaagacg aacagctgag ccaagctgtc atcaacgaag ctgagcaagc
    22621 acatattcga tttgttccaa ctgtcatctt gggtaaagaa atctttgatg aatctatttc
    22681 aatagaggaa ttaaaagaat tgatccaaac aaaataaaaa aataaggagc gtgggacaaa
    22741 agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag cagaagcaac
    22801 tccttcttat ttcttggagt taaacgcttc tgtcccagcc tccttattcc gaataaatgg
    22861 tgtccaaaag cttgcatctg ccagattatc tcatttctta tgacaagcta agcaaattat
    22921 ctccaccaaa taatttattc atatttttga cttgcgcata ctaactaatt cttaaatttt
    22981 catacaaaat ttctcaattt cccttaacga gtaatattta tgtacggtga ttctcactag
    23041 tatcccaatc actttttaag ttatcccgat ttcaattcta cttcaaaaat agttgctttt
    23101 atgtatgctg ttagttgatt agatggtcat ttgttgagct aggtcgttta ttttaaacaa
    23161 gttgtttctt tagcttatac ctatctcgtc taccaaacgc aagatggcaa acacaaatgc
    23221 atacgcatct gtatttgcca ctttgattcg tataaagcta acaactatta actcctctca
    23281 gctaatagtt gctctctttt ttattcagat tcatttttgc tgatcacagc ctagtatttc
    23341 aatggttttg aacactaaac caaattgttc cattacaaca ttcactggct gatgaaatgg
    23401 attagtagat ttcgattatt caaagcgatt ttctattggt ggatcgtgtt cccaactaat
    23461 aagacggatt ccaaacctat cgtacagatc ttctaaacca cttataaatt ttgcacctat
    23521 ttcaggtgtt ttattgcgtg gatattctat tgttacgcca ttaaatggat accaattagg
    23581 attaggctct ctttttttct gtacatctcc catagaatag ttagcacttt ctgggacata
    23641 atatattctt cgaccatcct ctaattcatc taataagata tttcgtgatc gtctatcact
    23701 tgctaaatgt agacgccacg tgcgatacca tgccatgcta cctgcatctg cagaaaatcc
    23761 atcaaataat gcaacaattg tatcttctat cacaatcctt tccccatcta cttcatattc
    23821 taatctaaaa tcaaactccc ctcgggtaat ttctggtctt ggtggcttag gacccaatat
    23881 tattctactt aaaaccgcat tcgttcccag atgaaacaca gctataacaa caataatgat
    23941 taatattttg tttctatttg ataaatttct cattattcgc acatcacctc tacattctca
    24001 catattagtt cgtaatactc ctttaatatc aaaatatcta ctggtcgtaa taatattcgc
    24061 tatgaattcc tactactcgt ataagaaagg ccaaatcatc agcttttact tgctgatgat
    24121 ttggcttgtt tctatttatc gtaattgttt tctaatcacc aaaattgtta acaatcggtt
    24181 cagatatttc ccagttgatt aaggtaattc cgtattgtgt caaaacttct tgcgcttctc
    24241 cgaaattaag tacagttctt atgtatccac tttctcctaa tataaagtct acctctcttt
    24301 taaaaccttc ctcgagattt ctaagggcta tatgtggttt taatgacatt gattgtacat
    24361 tttcccccat ataatattgc gcacttcctc gactaaaata gattcctaga tcgtccccaa
    24421 aaggtagatc ttctctacca ctagctaatc tacttctcca tcttcgttct cttttcatag
    24481 aacctgcgct gaactcacac ccgttaaact cagctatgac agtatcttca attatgttaa
    24541 tctgtccatc tagttcgtat tcaatcctaa atggaaattc tccataggtg atttccggtt
    24601 cgggtatttt aggtgagatt aatgcaaaga aaggaaatat taagcttggc aacatcaaaa
    24661 aaactcctcc tatgatcaca attcccgatg taatccaaaa tataatttgt acaattctca
    24721 ttgatccatt gtattccatt ttattccccc tattactatt catatccgcc tatctatatc
    24781 gatcttccaa tgcagagata attgcttcca taccttgatt ttttactgag ttacctatgc
    24841 gagatatcat tctccactaa ggtgcatcat attgtctatc taacatgatt aattctccaa
    24901 taggtgtata ctcctccaaa aacaacattt aatgcatctc cctcgacaac ataagctacc
    24961 atgtttgctg tatatgtgtt tgagtctaat tcataagcag ataaatttac tgtcgctgga
    25021 ttaaatataa tcgcattcgt atttatagct actgaatttg ctgcttcagc accacctttt
    25081 gaatgtccga tcattgtgat ttcaatagta ggatttacgt ggacagccct caccgtttac
    25141 cctgaccatt atagaaatcg cttacttttt tgaactacgc aacaaaggat acaatgctcc
    25201 taacttcact gtctccattt ttgtccacta aggaatataa aaaataggca ttaattcatt
    25261 taattcggtc acaacacgtt accttttaaa tcattatact gtatctcata cattattatc
    25321 aataaactat tataaaaatg caaaaaatgc tttatcaatc tattttgtaa ttggtcataa
    25381 tatcattgaa atcataccct gtatcgattt ttcctatgaa tctcgtctat ttgtgattga
    25441 cgaaaaagag gcaagacaga cactggaatg gtaattttac ccactatttt gctccaacta
    25501 tttgtaatcg tacccacttt tgaaataccg agatgatcat tttaattgat atgctgattc
    25561 ccaagcaaaa ccccaagaaa ttaaatgctc tatcgcatct agcttcttgg gttttgctta
    25621 tataaattcc aacatttaaa ttttttatgc tgttcggtct cagaaatgcc gtttttgctt
    25681 atatcacaat atcaagatgt caaattattc gtgttgccga tgactttgat taattttttt
    25741 caaattgttt attaagacta atgctgtctt tttgcagata ccaatgttcg aactttttaa
    25801 cattatcata tgatcctgca agttttaact tcttaccatt agatgttatc aaagttataa
    25861 ttaaccttgc ctttttccca ttaggatctt ttattttatg aattttctgc aggtaatctc
    25921 tcctaatggc agctattttt acctcatcag tgctgataaa ccattgatca tccacataca
    25981 tactgcctgt tatgttgtgt ttttccattt cttccgagaa cgaaaagttt aaggctcgtt
    26041 cttacttcca aagttgaatg agtccatgga ttggacttag tgtgagaatt gagaacaaca
    26101 ataagaatcc atatcctccc gcaaacatcc ctaaggctat actgtctctc catccataag
    26161 taggattaga agagaaaaga gtcaccgttt gtaataatat gaaaaggaat aatccagcac
    26221 aaacaccaaa gataacaact ccaaacattg aatttttata caatgaccat ttatttatag
    26281 gcttttcttt cattttactt ccccctactg ttctgttcac acggaatgaa ttcaaagttc
    26341 ataagccctc ctctttgaac atatgaatac gacttgctaa ctatacttta aaaaagcttg
    26401 ttttaagcgg ttataggcga gttgtaatct ctattcatct cattagcaaa taacttgccg
    26461 aaaagtctac tgaaattaaa gcagatagtg gaagaattat ttagccagga tagacactat
    26521 ttgtgaaaca catgtcttta cttttgaaat tctatgatga aaagccttgg aatacagtag
    26581 ctcttaattg gtaatacttt ttccattata aataacctct tttcatttta tatttatccc
    26641 ctctaaaaat aatatctaat ctaatatttt aaacttatat ttccctcgct gtgctaatag
    26701 agcattacta aataaataga aactagaaaa aagcattacg cctgccagaa taaaccaatt
    26761 atttgt
//
LOCUS       DADVXK010000028        26765 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.028, whole genome shotgun sequence.
ACCESSION   DADVXK010000028 DADVXK010000000
VERSION     DADVXK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.028"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..544)
                     /locus_tag="KB909_001097"
     CDS             complement(<1..544)
                     /locus_tag="KB909_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6837146.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYI"
     gene            complement(677..1360)
                     /gene="rpiA"
                     /locus_tag="KB909_001098"
     CDS             complement(677..1360)
                     /gene="rpiA"
                     /locus_tag="KB909_001098"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBB6837147.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            1679..2092
                     /gene="rpsL"
                     /locus_tag="KB909_001099"
     CDS             1679..2092
                     /gene="rpsL"
                     /locus_tag="KB909_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBB6837148.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            2176..2646
                     /gene="rpsG"
                     /locus_tag="KB909_001100"
     CDS             2176..2646
                     /gene="rpsG"
                     /locus_tag="KB909_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBB6837149.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            2740..4827
                     /gene="fusA"
                     /locus_tag="KB909_001101"
     CDS             2740..4827
                     /gene="fusA"
                     /locus_tag="KB909_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6837150.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            4999..6186
                     /gene="tuf"
                     /locus_tag="KB909_001102"
     CDS             4999..6186
                     /gene="tuf"
                     /locus_tag="KB909_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6837151.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            6593..6901
                     /gene="rpsJ"
                     /locus_tag="KB909_001103"
     CDS             6593..6901
                     /gene="rpsJ"
                     /locus_tag="KB909_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBB6837152.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            6932..7561
                     /gene="rplC"
                     /locus_tag="KB909_001104"
     CDS             6932..7561
                     /gene="rplC"
                     /locus_tag="KB909_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBB6837153.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            7589..8212
                     /gene="rplD"
                     /locus_tag="KB909_001105"
     CDS             7589..8212
                     /gene="rplD"
                     /locus_tag="KB909_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBB6837154.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            8212..8502
                     /gene="rplW"
                     /locus_tag="KB909_001106"
     CDS             8212..8502
                     /gene="rplW"
                     /locus_tag="KB909_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBB6837155.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            8541..9374
                     /gene="rplB"
                     /locus_tag="KB909_001107"
     CDS             8541..9374
                     /gene="rplB"
                     /locus_tag="KB909_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBB6837156.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            9417..9695
                     /gene="rpsS"
                     /locus_tag="KB909_001108"
     CDS             9417..9695
                     /gene="rpsS"
                     /locus_tag="KB909_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBB6837157.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            9718..10065
                     /gene="rplV"
                     /locus_tag="KB909_001109"
     CDS             9718..10065
                     /gene="rplV"
                     /locus_tag="KB909_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBB6837158.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            10079..10735
                     /gene="rpsC"
                     /locus_tag="KB909_001110"
     CDS             10079..10735
                     /gene="rpsC"
                     /locus_tag="KB909_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBB6837159.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            10738..11172
                     /gene="rplP"
                     /locus_tag="KB909_001111"
     CDS             10738..11172
                     /gene="rplP"
                     /locus_tag="KB909_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBB6837160.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            11162..11350
                     /gene="rpmC"
                     /locus_tag="KB909_001112"
     CDS             11162..11350
                     /gene="rpmC"
                     /locus_tag="KB909_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBB6837161.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            11375..11641
                     /gene="rpsQ"
                     /locus_tag="KB909_001113"
     CDS             11375..11641
                     /gene="rpsQ"
                     /locus_tag="KB909_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBB6837162.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            11699..12067
                     /gene="rplN"
                     /locus_tag="KB909_001114"
     CDS             11699..12067
                     /gene="rplN"
                     /locus_tag="KB909_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBB6837163.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            12104..12412
                     /gene="rplX"
                     /locus_tag="KB909_001115"
     CDS             12104..12412
                     /gene="rplX"
                     /locus_tag="KB909_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBB6837164.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            12440..12979
                     /gene="rplE"
                     /locus_tag="KB909_001116"
     CDS             12440..12979
                     /gene="rplE"
                     /locus_tag="KB909_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBB6837165.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            12998..13183
                     /locus_tag="KB909_001117"
     CDS             12998..13183
                     /locus_tag="KB909_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBB6837166.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            13219..13617
                     /gene="rpsH"
                     /locus_tag="KB909_001118"
     CDS             13219..13617
                     /gene="rpsH"
                     /locus_tag="KB909_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBB6837167.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            13649..14185
                     /gene="rplF"
                     /locus_tag="KB909_001119"
     CDS             13649..14185
                     /gene="rplF"
                     /locus_tag="KB909_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBB6837168.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            14346..14702
                     /gene="rplR"
                     /locus_tag="KB909_001120"
     CDS             14346..14702
                     /gene="rplR"
                     /locus_tag="KB909_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBB6837169.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            14723..15223
                     /gene="rpsE"
                     /locus_tag="KB909_001121"
     CDS             14723..15223
                     /gene="rpsE"
                     /locus_tag="KB909_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBB6837170.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            15238..15417
                     /gene="rpmD"
                     /locus_tag="KB909_001122"
     CDS             15238..15417
                     /gene="rpmD"
                     /locus_tag="KB909_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBB6837171.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            15461..15901
                     /gene="rplO"
                     /locus_tag="KB909_001123"
     CDS             15461..15901
                     /gene="rplO"
                     /locus_tag="KB909_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBB6837172.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            15901..17196
                     /gene="secY"
                     /locus_tag="KB909_001124"
     CDS             15901..17196
                     /gene="secY"
                     /locus_tag="KB909_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBB6837173.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            17258..17905
                     /locus_tag="KB909_001125"
     CDS             17258..17905
                     /locus_tag="KB909_001125"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBB6837174.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            18096..18314
                     /gene="infA"
                     /locus_tag="KB909_001126"
     CDS             18096..18314
                     /gene="infA"
                     /locus_tag="KB909_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBB6837175.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            18347..18463
                     /gene="rpmJ"
                     /locus_tag="KB909_001127"
     CDS             18347..18463
                     /gene="rpmJ"
                     /locus_tag="KB909_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBB6837176.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            18481..18846
                     /gene="rpsM"
                     /locus_tag="KB909_001128"
     CDS             18481..18846
                     /gene="rpsM"
                     /locus_tag="KB909_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBB6837177.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            18874..19263
                     /gene="rpsK"
                     /locus_tag="KB909_001129"
     CDS             18874..19263
                     /gene="rpsK"
                     /locus_tag="KB909_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBB6837178.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            19343..20281
                     /locus_tag="KB909_001130"
     CDS             19343..20281
                     /locus_tag="KB909_001130"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBB6837179.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            20309..20689
                     /gene="rplQ"
                     /locus_tag="KB909_001131"
     CDS             20309..20689
                     /gene="rplQ"
                     /locus_tag="KB909_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBB6837180.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            20961..21800
                     /locus_tag="KB909_001132"
     CDS             20961..21800
                     /locus_tag="KB909_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6837181.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            21776..22645
                     /locus_tag="KB909_001133"
     CDS             21776..22645
                     /locus_tag="KB909_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6837182.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            22635..23432
                     /locus_tag="KB909_001134"
     CDS             22635..23432
                     /locus_tag="KB909_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6837183.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            23635..24381
                     /gene="truA"
                     /locus_tag="KB909_001135"
     CDS             23635..24381
                     /gene="truA"
                     /locus_tag="KB909_001135"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6837184.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            25046..25283
                     /locus_tag="KB909_001136"
                     /pseudo
     CDS             25046..25283
                     /locus_tag="KB909_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(25427..26203)
                     /locus_tag="KB909_001137"
     CDS             complement(25427..26203)
                     /locus_tag="KB909_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6837185.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            26326..26733
                     /locus_tag="KB909_001138"
     CDS             26326..26733
                     /locus_tag="KB909_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBB6837186.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT         8758 a         4893 c         5666 g         7448 t
ORIGIN      
        1 tgatatattt ataacatgtt ccaactgaaa caccgcattt tgaagaaata aattggatcg
       61 tttctttttt ttcataatag agacgtcgga tttttttgat cgtttttgca tcgatttttg
      121 gtcttccgcc gatttttcct tttttacgag cttcatctaa tccaactaat gtacgttctt
      181 tgatcaatgc gcactccatg tttgctaggt tttccattaa ttggaaatag atttttccca
      241 tttcgcgcgt atcgattcct tcatcaagac taatcaagtg cagcccgcga tctttgaata
      301 attgcgtgag ttctgttaat tgccgcgtag atttgcctaa tcgatgaagt tggcaaatga
      361 ctagtgcatc gccttgttgc atgtcagcga tcactgactc caaatgaaca gcagtagaat
      421 cattttgttc cacttcatat gtctcatgga aaatttcttg acaaccaaag tcagataatt
      481 gatcaacctg agttgttaaa tcaacgtcat ttatggttgt gcgtgcataa ccaataattt
      541 tcatggtgat tcctttctag cagtgatttt ctaactggat ataacagtaa aaatgtagca
      601 taaagtacgt caaaaagata gttttttcgc aaattttccg ctgtcttttt ttattggatg
      661 atcaagcagt ttttctttat ttacgacgga ttgcgtcaag aatctcaacg cctttttctg
      721 agccgacaac tactttagaa accatgttta ggaaaagccc atgttctact accccaacaa
      781 gttcatctaa ataggtagct aagctttctg gctgttcgat gacttctaga tgcagatcaa
      841 tgatgtaatg accaccatct gtggttaaga cttctccgtt ttcgtctgta cgcaagacgg
      901 gttggaatct tttttcttca aaaatatgaa gtagctgttg ggagccataa gggatcactt
      961 caactgggag tgggaacttc ccaagtttat cgactaattt agaagaatca acgatccaaa
     1021 tcgtttcttt tgagtacgta gcgactattt tctcgaaaag caaagcagcg ccgccgcctt
     1081 tgatcccttg aaaatcagca ctgatttcat cagcaccgtc tattgtcaaa tcgactacgg
     1141 ggacttcatc aatactcttt aacggtattc ctaatttttc cgcttgttct tttgtcgcat
     1201 ttgaagtagt aactcctgtg atacgtaaac cttcttcacg catacggcga ccaatctctt
     1261 ctaccatata ataggcggtt gaaccggtcc cgagacctac gatcatcccg tcctttacga
     1321 atttcgcggc ttcaatgcca gctaattgtt ttaaattcat ctttgcgtcc accttttttt
     1381 agtttgagca tcgtgctttc ctcactattt tagcgtgatt tacggtaaaa agataccatt
     1441 cttttttatt ccaataaagc tttttcaaaa aaaattgcat ctcttgttga catgtttttt
     1501 cattcgtgat attctaacaa aggtgcttta tctacaggtt tctgtgaaga aacgtgctga
     1561 ctgtttatca aagcatattt gataaggatg cagacattgc atttattttt tatcacaaaa
     1621 aaagaaccac ctggatgtgt ggaactagac gcaaatcgtg ggaaggagga aacaaggaat
     1681 gcctacaatt aaccaattag tacgtaaacc tcgtaaatca aaggtggaaa aatctaattc
     1741 acctgctttg aacaaaggat ataacagctt taagaaaact caaactaacg taaactcacc
     1801 tcaaaaacgt ggggtagcaa ctcgtgtggg tacaatgaca cctaaaaaac cgaactcagc
     1861 tttacgtaaa tatgcacgtg ttcgtttgtc aaacttaatt gaagttactg cttatatccc
     1921 agggattggt cataacttac aagaacacag tgttgtatta ttacgcggtg gtcgtgtaaa
     1981 agacttacca ggggtacgtt accatatcgt tcgcggtgct ttagatactg ctggtgttaa
     2041 cgaccgtaaa caaagccgtt ctaaatacgg aactaaaaaa cctaaagctt aattttaatt
     2101 attaaacaaa tgaaacttgc ttctactata tagaagtaat tactatgaac aatatttcgg
     2161 aaggaggagt tacggatgcc acgtaaaggt cctgttgcaa aacgtgatgt tttaccagat
     2221 cctatttata actcaaaatt agtaactcgc ttgatcaacc gtgtaatggt tgacggaaaa
     2281 cgcgggattg cagctaacat tatctataat gcctttgact tgatcaaaga atctacaggt
     2341 aacgatccat tagaagtgtt tgaacaagca atgaaaaacg ttcaacctgt tcttgaagtt
     2401 aaagcacgtc gtgttggggg ttcaaactac caagtaccag ttgaagttcg ccctgaacgc
     2461 cgcgttactc taggtcttcg ttgggtagta aactacgctc gcttgcgcgg tgaacacaca
     2521 atggaagaac gcttagcaaa agaaatcatg gatgctgcaa acaacacagg tgcttctgtt
     2581 aaaaaacgtg aagacactca taaaatggct gatgccaacc gtgcgtttgc tcactatcgc
     2641 tggtaagatt ctctctgttt ggtcggcttt tataagtcga cctcagatag tgtccttatt
     2701 tttagcaact agatagtaaa gagaggagaa acaaggagaa tgaccagaga attttcttta
     2761 caaaacactc gtaatatcgg tatcatggcc cacatcgatg ctggtaaaac gactgctact
     2821 gaacgtatct tgtactatac tggtaaaatc cataaaattg gtgaaactca tgaaggagct
     2881 tcacaaatgg actggatgga acaagaacaa gaacgtggta ttacgatcac ttctgctgct
     2941 actacagcac aatggaaggg tcaccgaatc aacatcatcg acacaccagg acacgtagac
     3001 ttcacagttg aagttgaacg ttcattgcgt gtacttgatg gtgctgtaac tgttcttgat
     3061 gcacaatcag gtgttgaacc tcaaactgaa acagtttggc gtcaagcaac aacttatggt
     3121 gtacctcgta tcgtatttgc aaacaaaatg gacaagatcg gtgctgactt cttatattca
     3181 gtatcaactt tacatgaccg tttgcaagca aacgctcacc caatccaatt accaattggt
     3241 gcggaagacg acttcacagg aattatcgac cttgtaacaa tgaaggctga aatgtataca
     3301 aacgatcttg gaacagagat cgaagaaaca gaaattcctg aagaataccg cgaattagct
     3361 gaagaatggc gcgaaaaatt ggttgaagct gtagctgaaa ctgatgaaga acttactttg
     3421 aaatacttag aaggtgaaga aatcactgaa gctgagttaa aagaaggtat ccgccgcgca
     3481 acagttaacg tagaattcta cccagtacta tgtggttcag catttaagaa caaaggggtt
     3541 caattactat tggacgctgt tcttgattac ttgccatcac cgttagatat cccagctatc
     3601 aaagggattg accctaaaac tgatgaagaa gtagaacgtc ctgcagacga cagcgctcct
     3661 ttctcagctt tagcatttaa agttatgact gacccattcg taggtcgttt aactttcttc
     3721 cgtgtgtact ctggtgtttt acaatcaggt tcatacgtac aaaacgcaac aaaaggcaaa
     3781 cgtgaacgtg ttggtcgtat cctacagatg catgccaact ctcgttcaga aatctctgaa
     3841 gtttacgctg gagatatcgc tgctgctgtt ggtttgaaag acacaactac tggggacaca
     3901 ctatgtgatg aaaagagtct agttattctt gaatccatgg aattcccaga accagttatc
     3961 caagtcgcta ttgaacctaa atcaaaagct gaccaagata aaatgggtgt ggctttacaa
     4021 aaactatctg aagaagatcc tactttccgt gctgaaacaa acgtggaaac aggcgaaaca
     4081 atcatcgctg gtatgggtga acttcactta gatatcatcg ttgaccgtat gcgtcgtgaa
     4141 ttcaaagttg aagctaacgt aggtgcgcct caagtatctt accgtgaaac tttccgtgct
     4201 ggcactcaag ccgaaggtaa gtttgtacgt cagtctggtg gtaaaggtca atacggtcac
     4261 gtatggattg aatttacacc aaatgaagaa ggtgctggtt tcgaatttga aaatgcgatc
     4321 gtcggtgggg ttgttcctcg tgaatacatt ccagctgttg aaactggttt gaaagatgct
     4381 atggaaaatg gtgtcttagc tggctatcca ttagtagata tcaaagctaa actttacgat
     4441 ggttcatacc atgatgtcga ttcaaatgaa actgccttcc gtgttgctgc ttctatggca
     4501 ttacgtgcag cagctaagaa agctaatcca gtaatccttg aaccaatcat ggctgtagaa
     4561 gttgttatcc ctgaagatta tttaggtgat gttatgggtc acgtaactgc tcgtcgtgga
     4621 cgtgttgaag gtatggaagc tcgcgctggc ggccaacaag ttgttcgtgc gatggttcca
     4681 cttgctgaaa tgtttggtta tgctacaact cttcgttctg ctactcaagg tcgtggtaca
     4741 tttacaatga catttgacca ctacgaagat gtaccaaaat cagtacaaga agaaatcatt
     4801 aagaaaaacg gcggaaaagc tgaataattt cttgaaaccg gatagtcctg caaagagatt
     4861 atccaaagag actatatttt taatatagtt tcgtgtaaaa taattatcga tgatatgggc
     4921 atgtggtgta ccttgtgtac atcatatacc tatcagacaa ataaaaaata tattgtattt
     4981 ttaggaggac attttaaaat ggcaaaagaa aaatttgacc gttctaaacc acacgttaac
     5041 attggtacta tcggacacgt tgaccatggt aaaactacat taacagctgc aatcacaact
     5101 gtactatcta agaaaaacgg cggccaagct atggcttacg atcaaatcga tggtgctcca
     5161 gaagaacgcg aacgcggaat cacaatctca acagctcacg ttgagtatga aacagataca
     5221 cgccactacg ctcacgttga ctgcccagga cacgcggatt acgttaaaaa catgatcact
     5281 ggtgctgctc aaatggacgg agctatcttg gtagtttctg ctgctgacgg cccaatgcct
     5341 caaactcgtg aacacatcct attgtctcgt caagttggtg ttccttacat cgttgtattc
     5401 ttgaacaaag tagacatggt tgatgacgaa gaattactag aattagttga aatggaagtt
     5461 cgtgacctat taacagaata cgaattccct ggtgacgatg ttcctgtagt tgctggatca
     5521 gctttgaaag ctctagaagg cgacgcttca tacgaagaaa aaattcttga attaatggct
     5581 gcagttgacg aatacatccc aactccagaa cgtgacaacg acaaaccatt catgatgcca
     5641 gttgaagacg tgttctcaat tactggacgt ggtactgttg ctacaggtcg tgttgaacgt
     5701 ggacaagttc gcgttggtga cgaagttgaa gttgttggta ttgctgaaga aacttcaaaa
     5761 acaacagtta ctggtgttga aatgttccgt aaattgttag actacgctga agctggagac
     5821 aacattggtg ctttactacg tggtgttgca cgtgaagaca tccaacgtgg acaagtttta
     5881 gctaaaccag gtacaatcac acctcataca aaattctctg cagaagtata cgtgttgaca
     5941 aaagaagaag gtggacgtca tactccattc ttcactaact accgtccaca attctacttc
     6001 cgtacaactg acgtaacagg tgttgttgaa ttaccagaag gaactgaaat ggttatgcct
     6061 ggcgacaacg taacaatgga agttgaatta atccacccaa tcgctatcga aaacggtact
     6121 aaattctcaa tccgtgaagg cggacgtaca gttggtgccg gtgtcgttac agaaatcaaa
     6181 gcttaattca cttaagtttt aaagtaaagc aacatttatt cggacgtaat cgctcggaac
     6241 gaaggtctta ggatctttgt tccgagcttt tttatttatt gcaggatcag gaaaaaagac
     6301 aggagtatta taaatagaag aaacacgaaa taaaagagtc agtattttct aaatgaaact
     6361 ttatgaaaac aaaatgtttt ttacaagaaa aagccttgct ttgtgagttt atatatatta
     6421 taatgacaaa ggtgcgttta ctttagtgaa ttgcacagac gtaatcagaa tgatttcgtc
     6481 ggctaagaaa cgagaggttg cgacacgccc ggacgctttg ccacgaacga gcgtgacgga
     6541 aattttcgtg gagctatgtc tacttttcaa aataggcgaa ggagggaaca agatggcaaa
     6601 acaaaaaatt cgtatccgtt taaaagcgta tgaacaccgt attttagatc aatcagcgga
     6661 taaaatcgtg gaaactgcaa aaagaactgg agctagcgtg tctggtccaa ttccattacc
     6721 aactgaacgc agtctttaca caatcatccg tgcgactcat aaatacaaag attcacgcga
     6781 acaattcgaa atgcgtacac acaaacgtct tatcgacatt gtgaacccaa caccaaaaac
     6841 tgttgatgct ttgatgaagc tagacttacc atctggtgta aacatcgaaa tcaaattata
     6901 aaactaaaac aaaaataatg gaggtgtact catgaccaaa ggaatcttag ggaaaaaagt
     6961 gggaatgaca caaatcttca ctgaatctgg tgaattaatt ccagtaactg ttgtagaagc
     7021 tactccaaac gtagtactac aagtgaaaac aatggaaacg gatggctacg aagctattca
     7081 agttggttac caagatatgc gtgaagtttt atcaaacaaa cctgcgaaag gtcatgttgc
     7141 aaaagcaaac acggctccta agcgcttcat tcgtgaattc aaaaatgttg agctaggaga
     7201 atatgaagta ggaaaagaaa ttacagtaga tgttttccaa gcaggagaca ttattgatgt
     7261 aacaggtact acgaaaggta aaggattcca aggggttatc aaacgccacg gacaaagccg
     7321 cggaccaatg gctcacggtt ctcgttacca tcgtcgtcct gggtcaatgg gtccagttgc
     7381 acctaaccgt gtatttaaaa acaaacgtct tgctggccgt atgggtggca accgcgtaac
     7441 tatccaaaac ttggaagttg tacgtgtcga tgcagaaaga aatgttatct tgatcaaagg
     7501 taatgttcct ggagctaaaa aatctttaat tactatcaaa tcagctgtga aagctaaata
     7561 attgtaggaa gaaaggagga actaaggaat gccgaatgta gcattattca aacaagatgg
     7621 aagccaaaac ggtgaaatca cacttaacga agaaatcttc ggaattgaac ctaatgaaag
     7681 tgttgtttac gatgcaatcg taatgcaacg tgcgtcatta agacaaggaa cacacgcggt
     7741 taaaaaccgt agcgctgttc gcggcggcgg acgtaaacca tggcgtcaaa aaggaacagg
     7801 tcgtgcacgt caaggatcta tccgctcacc acaatggcgt ggaggtggcg tagtctttgg
     7861 accaacacca cgttcttaca gctacaaact tcctaaaaaa gttcgtcgtt tagcaatgaa
     7921 atctgtattg tcagaaaaag ttgctgaaaa caacttggta gcaatcgaag gcttgaactt
     7981 cgacgcacca aaaacaaaag aattcaaaca agttcttgct aacttatcta tcgactctaa
     8041 agtattggtt gttctagaaa aaggtaacga ctttgctgct ttatcagcac gtaacttacc
     8101 aaacgtttct gtagtaactt ctgataatgt gagtgtgcta gacgttgtat caaatacaaa
     8161 agtgttagca acacaaactg ctcttactca aattgaggag gtgcttgcat aatgaactta
     8221 ctagacgtaa tcaaacgccc agtgatcact gaaaaatcaa tgcttgccat ggatgacaag
     8281 aaatacactt ttgaagtgga cactcgcgca aacaaaactt tagtaaaaca agcggtagaa
     8341 gctgcttttg acgttaaagt caaaaacgtg aacatcgtga acgtacgtgc gaaattcaaa
     8401 cgtatgggca aatatgcagg atatacaaaa aaacgtcgca aagcgatcgt tacattgact
     8461 gaagattcaa aagaaatcca attattcgaa gctgctgaat aagcactaat agataactca
     8521 ttaaattagg agggaaaaac gtggcgatta aaaagtacaa acctacctca aatggtcgtc
     8581 gtaacatgac aggttctgat tttgctgaaa tcacaacatc aacacctgaa aaatcattgt
     8641 tacaaccatt gaaaaaccat gctggacgta acaacaacgg ccgcatcact gtacgtcatc
     8701 aaggtggcgg acacaaacgc caatatcgcg tgatcgactt caaacgtaac aaagataacg
     8761 ttgttgcaac tgttcaaacg atcgaatatg atccaaaccg ttcagctaac atcgcgttag
     8821 tacactatga agatggagtg aaagcttaca tcttagcacc taaaggacta gaagtgggta
     8881 tgaaacttgt ttcaggtcca gaagcagata tcaaagtcgg aaatgctctt ccattagaaa
     8941 acattccagt tggtactgtt atccacaaca ttgaaatgaa acctggtaaa ggtggacaat
     9001 tgatccgttc tgctggtaca agtgctcaag tacttggtaa agaaggcaaa tacgtattga
     9061 tccgcttgaa ctctggtgaa gttcgtatga tcttagctgc atgccgtgct acaatcggtt
     9121 ctgtaggtaa cgaacaacac gaattaatca acatcggtaa agctggacgc tctcgttgga
     9181 tgcgtaaacg cccaactgta cgtggtagcg taatgaaccc taatgatcac ccacacggtg
     9241 gtggtgaagg taaagctcct atcggacgta aagcaccagt ttctccttgg ggtcaaccag
     9301 ctcttggtta caaaactcgt aacaaaaaag ctaaatcaga caaacttatt gttcgtcgtc
     9361 gcaaaaataa ataattactt tgaccatgtg tcgcacattt tgagaggagg ttcaccatgg
     9421 gtcgtagttt aaagaaagga ccttttgtcg atgagcattt aatgaaaaaa gttgaagctc
     9481 aagcaggggt tgaaaagaaa aaagttatca aaacttggtc acgccgttca acagttttcc
     9541 caagttttgt tggatatacc atcgcagttt atgatggacg taaacatgta ccagtttaca
     9601 tccaagaaga catggtagga cacaaattag gtgaatttgc acctacaaga acttatcgtg
     9661 gacatgctgc tgacgataag aaaacgaaac gctaatttga ggggaggata aatccaaatg
     9721 gcagaacaaa tcacatcagc taaagcaact gcaaaaacag ttcgcacttc acctcgaaaa
     9781 gcccgtttag taattgacct tatcagaggt aaaagtgtcg cagatgcaat ttcaatcttg
     9841 aaattcacac caaacaaatc tgctggaatc attgaaaaag tattgatgtc agcagttgcg
     9901 aatgcagaaa ataactttga cttagatgtt gaaaacttgg tagtaagcga agcttttgtt
     9961 aacgaaggac ctacaatgaa acgtttccgt cctcgtgcaa aaggatcagc ttctccaatc
    10021 aacaaacgta caagtcatat cacggtagtc gtatcagaaa aataaggagg gataatcagt
    10081 gggtcaaaaa gtacatccaa ttggaatgcg tgtaggcatc atccgcgact gggatgctaa
    10141 atggtatgct gaaaaagagt atgctgagtt cttacacgaa gatttaagaa tccgtaaatt
    10201 tatttcaact aaacttgctg atgctgctgt atcaacagtt gaaatcgaac gcgcaacagg
    10261 tcgcgtaaac atttcaattc acacagctaa accaggtatg gttattggta aaggcggttc
    10321 tgaagtcgaa agcctaagaa aagaattaaa caaattaact ggtaaaagaa tccatatcaa
    10381 tatcgtggaa atcaaaaaac cagatctaga tgcaaaatta gtaggtgaag gaatcgcacg
    10441 tcaattagaa aaccgtgttg ctttccgtcg cgctcaaaaa caagccatcc aacgctcaat
    10501 gcgtgctggc gctcaaggga tcaaaactca agtatctggt cgtctaaacg gagcagatat
    10561 cgctcgttca gaaggatact cagaaggaac tgttcctctt catactttac gtgcggacat
    10621 tgattacgca tgggaagaag cagatacaac atacggaaaa ctaggagtta aagtgtggat
    10681 ctatcgtgga gaaattcttc caactaaaaa aaacactgag aaaggaggga aataatcatg
    10741 ttagtaccta aacgtgtaaa acaccgtcgt gaattccgcg gaaaaatgcg cggggaagct
    10801 aaaggcggaa aagaagtagc attcggtgaa tacggtttgc aagctgttga ttcacattgg
    10861 atcacaaacc gccaaatcga agctgctcgt atcgcaatga ctcgttacat gaaacgtggt
    10921 gggaaagtat ggattaaaat tttccctcac aaatcttata ctgccaaagc aattggggta
    10981 cgtatgggtt ctggtaaagg ggcacctgaa ggatgggttg caccagtaaa acgtggtaaa
    11041 atcatgtttg aaatcgcagg cgttcctgaa gaagtagctc gtgaagcgtt acgtctagct
    11101 tctcacaaat taccaatgaa aactaagatc gtaaaacgtg aggaaatggg tggtgaatcg
    11161 aatgaaggtt aaagaaatca gagaattaac cactgccgaa atgcttgatc aagaaaaaca
    11221 attaaaagaa gaattgttta atcttagatt ccaattagca acaggtcaat tagaaaacac
    11281 tgcacgtatt aaagaagtac gtaaatcgat tgcacgcatc aaaactgtgt tgcgtgaaca
    11341 agctaagtaa ttatggaagg aggccattaa gcgtatgact gaaggaagaa atcaacgcaa
    11401 agtttatcaa ggtcgcgtgg tttcagacaa aatggataaa acaattaccg ttgctgtcga
    11461 aacaaagaaa aaccacccta tctatggcaa acgcatgaac tattctaaga aatacaaagt
    11521 gcatgatgaa aacaacacag caaaagttgg cgacatcgtg agaattatgg aaactcgtcc
    11581 attatcagct acaaaacgtt tccgtttgtt ggaagtagtc gaagaagcag ttattatcta
    11641 ataacacgag attttcctat atagattgaa tgcaaaatct gaaaggagga tacacaacgt
    11701 gatccaagca gaaagtcgtt taaaagtcgc tgataactca ggcgcacgtg aaattttgac
    11761 gatcaaagtc cttggtggat ctggtcgtaa aactgctaac atcggtgatg tgatcgttgc
    11821 tacggttaaa caagcaacgc caggtggggt tgtcaaaaaa ggtgacgtcg ttaaagccgt
    11881 tatcgttcga acaaaatcag gagctcgtcg tacagacggt tcatatatta aatttgatga
    11941 aaatgctgca gtgattattc gtgatgataa aagccctcgt ggaacacgta tctttgggcc
    12001 agttgcacgt gaactacgtg aaaacaactt catgaagatc gtttcactag caccagaagt
    12061 tttataatct tgagacactt atcaaaggag gtgcgaaaca gttatgtttg ttaaaaaagg
    12121 cgataaagtt aaagttatca ctggaaaaga caaaaacaaa gaaggcgttg tactagcagc
    12181 gttcccgaaa aaagataaag ttattgtcga aggtgtaaat gtcgttaaaa aacaccaaaa
    12241 accttctcaa gctgctcctc aaggtggaat tgttgagatg gaagcgccaa ttcatgtttc
    12301 taacgtgatg gtggttgact ctactggtgt agctggccga gttggctaca aagaagtaga
    12361 cggcaaaaaa gtccgtgttt ctaaaaaaac cggtgaagtt ttagataaat aaaagtttaa
    12421 ggaaggaggg tcttactgaa tgaaccgcct aaaagaaaaa tatcttaaag aagtaactcc
    12481 atcattgatg gaaaaattta actatagctc tgttatgcaa acacctaaag ttgaaaaaat
    12541 cgtcatcaac atgggtgttg gtgatgcggt atcaaacgct aaaaacttag ataaagcagt
    12601 tgaagaatta actttgatca ctggtcaaaa accaatgatt acaaaagcta aaaaatcaat
    12661 cgctggattc cgtttacgtg aaggaatgcc aattggtgca aaagttacat tgcgcggaga
    12721 aagaatgtac gaattcttag acaaattggt ttctgtttca ctaccacgtg tacgtgactt
    12781 ccatggtgta agtaaaaaag cctttgacgg tcgtggaaac tatactttag gtattaaaga
    12841 acaattgatc ttcccagaag tagattatga tttagtagat aaagtacgtg gtatggacat
    12901 cgttattgta acaacagcaa actctgatga agaatctcgt gagttgttga cacaattagg
    12961 catgccattc caaaaataat taaaggaggc gaactacgtg gctaaaaaat caatgattgc
    13021 taaaaacaaa cgtcctgcaa aattttcaac acaagcttat actcgttgcg aacgttgcgg
    13081 acgtccacat tcagtttatc gtaagttcca tctttgccgt atttgcttcc gcgaacttgc
    13141 ctataaaggt caaattcccg gcgtgaagaa agctagctgg taaaaagtaa attcgcataa
    13201 gaaggaggta aaagatcaat ggtcatgaca gatccaattg cagattttct aactcgtatc
    13261 cgtaacgcaa acatggttaa acatgagtct ttagaagtac ctgcatcaaa aattaaacgt
    13321 gacatcgctg aaatcttgaa acgtgaaggt ttcgttcgtg atgttgaata catcgaagat
    13381 gacaaacaag gcgtgatccg tgttttccta aaatttggta aaaacggcga acgtgttatc
    13441 acaaacttaa aacgtatctc taaaccaggt ttgcgtgctt atgtcaaagc tgacgaagta
    13501 ccaaaagtat tgaacggttt aggtatcgca atcatttcga cttctgaagg tgttgtcact
    13561 gataaagaag ctcgtgaaaa aaatatcggc ggcgaagtta tcgcttacgt atggtaatca
    13621 agtagaatct acaaggaggt gtctttaagt gagccgtatc ggaaataaag tcgttgttat
    13681 ccctgaagga gtaacagtta ctcaagacgg aaacaacgtt acagttaaag gaccaaaagg
    13741 tgaattgact cgtacttttt cagcagatat caaaatgaat atcgaaggaa acgaagtaac
    13801 tttcactcgt ccaaacgaca gtaaagaaat gaaaacaatt catggaacaa ctcgtgcgaa
    13861 cttcaacaac atggttgtag gtgtcagcga aggtttccaa aaagcgttag aactaatcgg
    13921 ggttgggtac cgtgcacaat tacaaggatc aaaacttgta ttgaacgttg gttactcaca
    13981 tccagtagaa atcacaccac cagctggagt aactgttgaa gtaccagcta acacacaagt
    14041 aattgttaaa ggtgcgaaca aagaagaagt tggcgaatta gctgcaaaca ttcgtggaac
    14101 tcgtcctcca gaaccttata aaggtaaagg tattcgttat gttggcgaat atgtacgccg
    14161 taaagaaggt aaaactggta aataatcgtt tagaaaaatt gcatagaagc cagcagcagg
    14221 aaaaaggcat ttggctgaag tttaccttca aaaaaataca tttttacttg tgccgcagct
    14281 tctatttttc gaaacgtatt tactgcttga aatagtagta caataaaaat aaagaggtga
    14341 caattgtgat tacaaaacca gataagaaca aaacacgtca aaagagacat cgtcgtgtac
    14401 gtaacaatat ctctggtact gctgagcgcc cacgcttgaa cgtttttcgt tctaacaaaa
    14461 acatctacgc tcaaattatt gatgacgtag cgggtgtaac gctagcaagt gcctctacct
    14521 tggataaaga aatttcaggt ggaacaaaaa cagaagcagc acaagctgtc ggtaaactag
    14581 ttgctgaacg tgcagctgaa aaaggcatta aagtagtagt ctttgaccgt ggtggatacc
    14641 tttaccatgg ccgtgtgcaa gctttagctg aagctgctcg cgaaaatgga ctagaatttt
    14701 agaagaagga ggaataccat tcatggttta tatcgatcca aaacatttgg aattagaaga
    14761 ccgcgttgtt gcaattaacc gtgtaacaaa agttgttaaa ggtggacgtc gtctacgttt
    14821 tgctgcttta gttgttgtcg gtgacaaaaa cggacacgta gggtttggta caggtaaagc
    14881 tcaagaagtt cctgaagcaa tccgtaaagc aattgaagat gcgaagaaaa acttagttga
    14941 agtacctatg gttggttcaa caatcccaca cgaagtaatc ggtgctttta gtggtggtag
    15001 aatcctaatg aaacctgctg tagaaggttc tggggttgct gctggtggac cagttcgtgc
    15061 cgtattagaa ttagctgggg tagcagatat cacttctaaa tctttaggct caaatacacc
    15121 aatcaacgtt gttcgcgcaa cagttgaagg tttgaaacaa ttgaaacgtg cagaagaagt
    15181 tgcagaactt cgcggcaaat cagttgaaga attaatcgga taaggaggac aacaataatg
    15241 gctgaattaa aagttacttt aaaacgcagt attatcggac gtcctcaaaa ccaacgcgat
    15301 acagttaaag cgttaggtct tacaaagatt aacagttcag tggttaagcc ttctaatgaa
    15361 gcaattaaag gcatgatcaa tactgtttct cacctagtgg acgttgaaga aatttaattt
    15421 agaaaaatca taactagaac attaaggagg tgccaaacct atgaaacttc atgaattaaa
    15481 acctgctgaa ggttcacgcc aagtacgtaa ccgtgttggt cgtggtactt catctggtaa
    15541 cggaaaaact gccggacgcg gacaaaaagg acaaaaagct cgttcaggcg gcggtgtgcg
    15601 tttaggattt gaagggggac aaacaccatt gttccgtcgt ttaccaaaac gaggattcac
    15661 aaacgtgaac cgtaaagact atgcagtcat taatcttgat gtattgaacc gctttgaaga
    15721 cggagctgaa gtaactcctg ttgctttagt tgaagctgga atcgtgaaaa acgaaaaagc
    15781 tggaatcaaa gtattagcta atggggaact aaacaagaaa ttaactgtga aagcagcaaa
    15841 attctctaaa gcagctcaag aagcaattga agcggctggt ggatcaatcg aggtgatcta
    15901 atgtttagac tattaaaaga tgcttttaaa gtaaaagaca ttagatcgaa aatcctattt
    15961 actgtatttg tgttgtttgt atttcgccta ggtgcacata ttactgtacc aggcgtaaat
    16021 gctgcttcat tgcaaaacct ttcttctttg ccatttttca acatgttgaa cttggtaagt
    16081 ggtagtgcga tgcaaaactt ttccattttc tcaatggggg tttcaccata cattactgct
    16141 tctatcgtca ttcagcttct tcaaatggac atcgtgcctc gatttgttga atggtcgaaa
    16201 caaggggaag ttggtcgtaa aaaactgaat caagcgactc gatatctgac attagtattg
    16261 gcatttatcc aatctgtcgg tatcactgct ggattcaatc aatacgctca attaggtttc
    16321 gtgaataatc ctaacgtagc aacttacgta acgatcggtt tgattctaac agccggtacg
    16381 atgtttgtta cttggctagg agaacagatc acagaaaaag gtatcggaaa tggcgtatca
    16441 atgatcattt ttgcaggtat catttctaga ttgcctgaaa gtatcagaga aatttatgaa
    16501 gattacttta taaatattga tccttcagac atatggaaat ctgctatttt tgtggccatt
    16561 ttactagtag cggtcttgtt gatcgtgaca ttcgtaacat ttttccaaca agctgaacgc
    16621 aagatcccga tccaatatac gaaacgcgta gctggcgcgc ctacaagcag ctatctgccg
    16681 ttgaaagtaa atgcagctgg agttattcca gttatctttg ctagttcgtt tattgctacg
    16741 ccaaatgctg ttttacaagc attgagcggt agattcggtt ctgaaaactg gtacaaagtg
    16801 atgatggaga tctttaacta taatacagca cctggtgcta cgatttatac gattctgatc
    16861 gttgccttca ctttcttcta cgcctttgtt caagtaaacc ctgagaaatt agcggaaaac
    16921 ttgcaaaagc aaggaagtta tataccaagc gtacgccctg gtaaggggac tgaagagtat
    16981 gtctcaagat tactgatgcg tttaagtaca gttggtgcag tcttccttgg tttagtggca
    17041 ttgcttccaa tcattgctca aatggtttgg gatcttccac aatcaatcgg attaggcggt
    17101 acaagcttac tgatcgttat cggtgtagct ttagaaactg cgaaacagtt agaaggctta
    17161 atgctgaaac gtaaatatgt tggattcatt gagtaagaaa gcgtgttgag gtttcccctc
    17221 aacacacgtt ctcacacatt tattaggagg gaaaacaatg aacctcattt taatggggct
    17281 gccaggcgca ggtaaaggaa cacaagctga aaaaatcatt gatgcttatg gtattccgca
    17341 catctcaaca ggagatatgt tccgcgcagc gatgcaaaac gaaacagctc ttggcctgga
    17401 agcaaagtct tatatggata aaggtgcatt agttcctgat gaagtaacaa atggaatcgt
    17461 gaaagagcga ctagctgaac cagatacaga gaaaggcttc ttattagatg gctttccacg
    17521 tacgctagat caagcaaaag ctctggacgc aatgctaaaa gatttgaata aaaaaattga
    17581 tgctgtcatc gatatccatg ttggtgaaga aatcttggtc gaacgtctag ccggccgatt
    17641 tatctgcagc aattgtggag caacttacca taaaattttc aaccctacaa aagttgaaga
    17701 cacatgtgat cgttgcggtg ggcatgaatt ctatcaaaga gaagatgata aacctgagac
    17761 ggttaaaaat cgtctggcta tcaacatcaa aaatagtgaa ccaatcttgg cttattataa
    17821 agaacaaggt ttgctaaaca ctattgatgg tgctcgtgaa atcgatgctg tatttgcaga
    17881 tgtacaaaaa atcattgaaa aatagcacga ttgcccgtag ccgacttgca ttatgcagtt
    17941 actcttgtca agttcaataa attatgatag aatatgtcag tccgacttct agagaatcct
    18001 ctagatgatc cattttgaga attttgaggt gggaactgca gtttccgcca ttttatcgtg
    18061 tgaaaatgcg aaacaagtac aaggaggtac tgtgcgtggc aaaagaagat atgattgaag
    18121 tcgaaggtac agtcgtcgaa actttgccga atgcaatgtt taaagttgaa ctagaaaacg
    18181 gacaccaagt tcttgctact gtttcaggta aaattcgtat gcattacatc cgtatcttac
    18241 ctggtgacaa agtaacggtt gaattgtctc catacgatct taaccgtggc cgtattactt
    18301 atcgctttaa ataattgtac tccgtaaaac tacaggaggt attatcatga aagtaagacc
    18361 atcagtaaaa ccaatgtgcg aacattgtaa agtaattcgt cgtaaaggac gcgttatggt
    18421 gatttgccca gcaaatccaa aacataaaca acgtcaagga taattggagg tgctataaat
    18481 atggctcgta ttgcaggagt agatattcct cgtgataaac gtgtagtagt ttcacttact
    18541 tatatctatg gtattggtaa cactactgct aaaaagatct tagctgatgc tggtgtatct
    18601 gaagatgttc gcgttcgtga attaacgaat gaacaaacag atgctatccg tgcagaagta
    18661 gataaattaa aagttgaagg ggatcttcgt cgtgaagtga acttgaacat caaacgtttg
    18721 atggaaatcg gttcttaccg tggaatccgt catcgccgtg gattgcctgt tcgtggacaa
    18781 aacacgaaaa acaatgcacg tactcgtaaa ggcccagctc gcgctatcgc tggcaagaaa
    18841 aaataattct taagtgaagg aggttaaaac ttcatggcag caaaaaaagt gaatcgtaaa
    18901 cgccgtgtga agaagaatat agaagcaggt attgcacata tccattctac attcaataac
    18961 actatcatca tgatcactga tactcacgga aatgcattag cgtggtcatc agctggttca
    19021 ttaggtttca aaggaagcaa aaaatcaact ccttttgccg ctcaaatggc agcagaaact
    19081 gctacaaaag cagcaatgga acacggatta aagactgttg aagtaacagt taaaggacct
    19141 ggttctggac gtgaagcagc aattcgttca ttacaagcta caggtttaga agtgactgca
    19201 attcgtgacg tgactccagt tcctcataat ggtgcccgcc ctccaaaacg ccgtcgtgtt
    19261 taatgagtgc cgctcatttt gagttttatc agtaacgtca ttgaacaaga cacttttcgt
    19321 tttgaaaggg gtaaagataa gaatgattga gttcgaaaaa ccaagaatcg caaaaattga
    19381 tgaagaaaaa gattatggca agttcatcgt tgaacctctt gaaagagggt atgggactac
    19441 tttagggaat tccctacgtc gtattttatt atcttctttg ccaggtgctg ccatcactaa
    19501 tattcaaatc gatggtgtac tgcatgaatt ctctaccatc aaaggtgtta gagaagacgt
    19561 cactcaaatc atcttgaaca ttaaaggctt agcgctgaaa atgtatggcc aagaagaaaa
    19621 aacccttgaa atcgatatta ccggacctgc tacagtaact gctggcgata ttatcgttga
    19681 tagtgatgta gaaattctta acaaagatat gtacatctgt agtgtctctg aaggagctac
    19741 gttccatgct cgcttaacag tgaaacctgg acgtggttat gttcaagcag atgaaaataa
    19801 aaaagaagat atgccaattg gcgttcttcc agtcgattca atctacacac ctgttcgtcg
    19861 tgtgaactat caagttgaga acacacgtgt tggacaccgt gaagattttg ataaattgac
    19921 gatggagatt tggacagatg gttcaattga accgttggaa gcaatgagtt tgtctgcgaa
    19981 aatcatgact gaacatttgg atatttttgt gaacttaact gatgaagcaa aaaatgctga
    20041 aatcatggtc gaaaaagaag aaacacaaaa agaaaaaatg ttggaaatga cgatcgaaga
    20101 gttagacttg tctgttcgct cttacaattg tttgaaacgt gcaggaatca atactgtaca
    20161 agaacttaca aataaatctg agcctgaaat gatcaaagtc cgtaacttag gacgtaaatc
    20221 attagaagaa gttaaagcaa aattgcacga cttaggttta ggtttacgta aagaagatta
    20281 aaacctttta cgaaggaggg aaaccaacgt gagttatcgt aaactaggac gcacatctag
    20341 ccaacgtaaa gcgatgttgc gtgatttaac aactgattta ttaatcaacg aacgtattgt
    20401 gactactgaa gctcgtgcga aagaagttcg ctcaactgca gaaaaaatga tcactttagg
    20461 taaacgcgga gatttgcatg cacgtcgtca agctgcggct ttcgtacgta atgaagttgc
    20521 cagcgtgcgt gaagaaaatg aggacatcgt cattgaatca gctttacaaa aactgttcaa
    20581 cgatattgca cctcgttacg cagaacgtca aggcggatac acacgcattt tgaagacaga
    20641 accaagacgc ggtgatggtg caccaatggt tgtcttagaa cttgtctaaa atcacactaa
    20701 taacatcact ttatagatga ttcttttaga gtgttatgat gttggaagat atttttccga
    20761 gtctagctca gcgctgctcc tcaagcgaat atcgcttggg gagtaagcac tcatcataaa
    20821 gtgttttttt ataccttcaa ttacctgtca tgacagatat gtttgaaggc ataaaaaaac
    20881 attttaagcg agaaataatt gaaaattttg tctttttttg atagtgttag taggaacttt
    20941 aggatgaaga aggagtaatc atggagccaa ttattgaatt agaaaagata aattataaat
    21001 accagccaga tgatcttcgc cccgcattga aagatgtctc ctttacaatt gataaaggtg
    21061 agtggatcgc tattattgga cacaatggtt caggaaaatc gacacttgcc aaaacgatca
    21121 atggattgct tctgccagaa tcagggatcg tgaaagtggg aaatcaaata ttggatgaag
    21181 aaaatatttg gacgatccga cagatggttg gaatggtttt tcaaaatcca gacaatcagt
    21241 ttgttggttc gacagtagaa gatgacgttg cttttggtct tgaaaatcaa gggattccca
    21301 gagaagaaat gctagtgcgt gtgaaagatg cacttgagaa agttagaatg gctgagtttg
    21361 cttcacgcga gcctgctcgt ttatcaggag ggcaaaaaca acgtgttgcc attgccggcg
    21421 tggttgcctt acgacctgat atcattattt tagatgaagc aaccagtatg ctagatccag
    21481 aaggtcgtga agaagtgatc tctacgatca agaagatcaa agaagaaagt caattgaccg
    21541 ttatatctat cactcatgat attgatgaag cagctaatgc caatcggata ctagtgatga
    21601 gacaaggcga acttgtccgt gaaggtacac caaaagaaat tttttctgct ggtcctgaac
    21661 tgatcgactt aggtctagat ctaccatttc ctgaaaaact gaagagcgca ctgaaagaac
    21721 gtggggttga tgtgcccagt gaatatatga cagaagaaag gatggtggat tggttatgga
    21781 catccgtttt gaacaagtag acttcactta tcagccgaat acaccatttg aacaaagagc
    21841 cttatttgac atcaatatga cgatcaaaga aaacagttat actgcattag tagggcatac
    21901 cggaagcggg aaatcaacct tacttcagca tttgaatgcg cttgttaagc caacaagcgg
    21961 tacagtccat attggagaac gagatattca gccggatacg gataataaga atttaaagcc
    22021 catccgaaaa aaagttggca tcgtctttca gtttccagaa gcacagctat tcgaagaaac
    22081 ggtagcaaaa gacattgctt tcggtcctaa aaactttggt gtcagcgaag aagaagcact
    22141 agtcctagca aaagaaacat tagaacaagt tgggctggat gaaagctatt tggaacgttc
    22201 gccatttgaa ctttcaggag ggcaaatgcg tagagtagca atcgctggtg tgcttgccat
    22261 gaggccggaa gtacttgtat tggatgaacc aacggcagga cttgatcccc agggtagaaa
    22321 agaaatgatg gagatgtttt ggcgtcttca taaggaacag cagatcacta ttgtattagt
    22381 tacgcattta atggatgatg tagccaattt tgcagattat gtctatgtgt tggaaaaggg
    22441 acgaatcgtt aatagcgggg agccgcaaga ggtctttcaa aacattgaat ggctaaaaga
    22501 aaaacaacta ggcgtaccta ctgccaccga gtttgcagaa gaattaatgg ctaaagggat
    22561 gaactttgct accttgcctt tgacagctga agaattagca gacgctatcg tccattatgc
    22621 tggaggaaat gcccatgatg aataaattga tatttggtcg ttatatgcct ggagattcct
    22681 tgatccatcg attggatccc cgagctaaat tattagccag tttttatttt atcggaatca
    22741 tttttttagc aaataattgg gaaacgtacc ttttgttggc atttttcaca ttactttctg
    22801 tcttcttgtc aaaagtagat ttgaaatttt ttatccgagg cattcgccca ttgatctggc
    22861 taatcctctt cactgtagct ttgcaggtct tgtttacaag tggcggagaa acttattgga
    22921 gttggggtgt tttccatatc actgaatttg gtgtgatgaa cggcctcttt attttctgtc
    22981 gattcgtgtt gatcattttt atgtcgactc tactcacgct tactacaccg cctttggaat
    23041 tatcggatgc gattgagtac ttgcttcgtc cattgaaagc cgtacggttc ccagtccacg
    23101 aaatttcatt gatgctgtcg attgctcttc gttttgtgcc tacattgatg gacgaaacag
    23161 aaaagatcat gaacgctcag cgcgctcgcg gtgttgattt tggtgaagga aacctagttc
    23221 agaaaatgaa agcagtcatt cctttgctga ttcctttatt tgtcagcagc ttcaaccgtg
    23281 cggaagatct tgcgactgct atggaagcaa gaggctacaa aggtggggaa ggaagaacga
    23341 aatatcgtgt attgcattgg cataatagag acacgatggt tatcattgct tttgtattat
    23401 taactgtgct actgatcttt ttgagaggat aaacgttcag tgggccgcta tctattcttt
    23461 tcttgctgat ctgtttgcaa gaaaggatgc gagcagtgta tgacaagaaa tattagggtc
    23521 tgtggcagac taaggtcaca ggcctctttc ttttatctga aaagaaagaa cgaaaaaatt
    23581 ttataaaaaa atcattattc cagataacct tttaggaaca aaggagagaa aaacatggta
    23641 cgttacaaag caatcattgc atacgacgga acaaatttta atggattcca aaaacagcca
    23701 aatgggcgta ctgttcaaga agaagtagaa aaaacattac aaaaaatggc aaatggaaaa
    23761 gaaatcacgg tctttggttc gggaaggaca gatgccggag tacatgcgat tgggcaagta
    23821 atccattttg attatccaga ggagcgtccg ttagaacgaa tgcgtttcgc gctagatacc
    23881 cagtcaccag aggatattgc tgtaagacaa gtagaaattg tttcagaaga cttccacgca
    23941 agatatttgg tcaaagaaaa gacgtatcaa tttcgagtgg atatagggaa accacgcagt
    24001 ccttttcgac gccattatgc aagttatttt ccttaccctc ttgatttgga aaaaattcag
    24061 cgggcgcttc ctgatttatt agggactcac gatttcacct ctttttgtgc atcaggaagc
    24121 tcgatagagg ataaagtacg tacgatctac gaggctaaga tggaggtaaa tgaaacaaaa
    24181 gacgaattgt tgtttacatt taggggaaat ggcttcttgt ataagatgat acggatctta
    24241 gtaggaacgc ttttgaaaat tggcaatggc cgattgcctg aagatagtat cccagatatt
    24301 attgcgaaaa aagatcgtaa tgcagcagga cctacagcac atcctgaagg actttatttg
    24361 tatgaagtga aatatgaata agaggttgtg acagaagtgg tcagcttcaa gaaataagaa
    24421 ggaatttacg aaaattactt ctcaaaattt tgcaaaattt cggcttattt tcgaaggagc
    24481 tacttctgga acaccgtgaa tcagaggttg tgaaaaagct gccctgcatc aagtaataag
    24541 aacaaccaaa caaaaatagc tcgtcatatt tttcgtttgg ttgggcttat taccgcagat
    24601 gcaagctttt gaacaccgtt taaggaagag gttgtgaaat cagcgttttg acctgagtat
    24661 tagagaaaca aacggaaaaa tagttcctca tattttgccg tttgttgagc taataccgaa
    24721 ggtcagctga ttgaacaccg tttaagaaag aggtcgtgag cctgtcattt aactctgagt
    24781 cacaagtaac aatttcaaaa aacagcttct catctttgat gaatatcgtg acttgtggac
    24841 gaggcgttga taagtgaatc atctttttgt tacctatttt ttctgtaacc aaaaaacgat
    24901 ggaacgttgt tttgattgcc cttaatgagg acagtcggaa caggtttgtc atttttatat
    24961 ttaaatggca caaatttttc taattatttg tcatttagcg ctgaaaattt ttgctattta
    25021 tctaaaaaag tgataactac ttaagatgaa gcagaatatt tacgccatac ggcatacaac
    25081 cgcgaaaaat ataaaaaaaa gaaaacgatt gaacgcgttt ttgcagtcgc aaaggaaaag
    25141 catggaatgc gctacatcaa gtatcgagac ttggaaaaca atcaggtgta tacgctgatt
    25201 gtttttgctg caatgaatct gaaaaagttg tccacttggc agttggaaca tatgtcttca
    25261 tatcttttat tatacaaaaa tagcaaaagc accagtctac actcttagta aagaggaaac
    25321 tgatcctttt gtctacattc ttaaagtact taaactaagt actttatttt actctttagg
    25381 attgatacag tagcatctat ccctttatta ataatctttt atttttttaa ataaagatgt
    25441 tgtctccatc ttcaggcact aaaacttttt cggaaattcc tttttcttta ttgaaagact
    25501 ttaattcttc tcttgacagt ccccaatggt ttacagcttc catatgaacg gcaataattg
    25561 tggaatctgg tattgcttta tgcaattcat ataaatcgtc tttccccata ataagagatt
    25621 ctccaactaa aaaatgatta tctccagcat ttgctactat gatttctgga ttatactgat
    25681 caatagtttg tttaacagct tcataccaaa ctgtatctcc tgtaaagtat agtgtcttct
    25741 cagtcgaatg tttgaaaaca ataccgcaaa cattacctac ataattcaag atttctcctc
    25801 tgccatgttt gccttttgtt ttaaccaatt gtatagattc aaaaactgtg tcttctcgta
    25861 gtacctccac atttttaaaa ccatatagtc gaatttcatt cgcatcattt tcatcttgca
    25921 caaataattt tatttcttta ggtaggacct ctttcgctat atcgtcccaa tgatctagat
    25981 gtaaatgtgt tacaataaca gcatcaatac cgttgataat atcttcgact ggcattggca
    26041 aatcaactag aggattcatt tgatcttttc ttggtgatgg aaaaggacct ttcgaaataa
    26101 atggtggaag tgttcctttt tccgctaaca ttggatcaat taaaaatttt ttacctccat
    26161 agtctaagat agctgttgca ttacgaatgt gatgtatatt cataaacgtt gtctcctttt
    26221 tgttgatatg aaatattttt agtataattc aattccatac aataaataaa ccgaacaaaa
    26281 aaagtctttt actattttta cttaatttat gaaaggttgt ttaccatgtt agaccaaaca
    26341 gatataaata tcattgagga actatcaaaa aatagtcgaa tcacaatgaa agaacttgga
    26401 gaaaaagtac atttgactgg acccgctgtc tcggcgagag tgacaaaact agaggaaagt
    26461 ggagttattg aaaattatac agtaaaatta aatatggaaa agctagggtt ttcgattcac
    26521 gcttttttaa ttataattac gcaaaattta aatcataaac cctatttatc atttattaaa
    26581 aatcatgaaa aattcttgat tagaaattat aagattagtg gagggggctg ttatcttttg
    26641 gaatgtagat ttacttcaaa aaaatcaatg aacagctttt tggaacagct taatgaatat
    26701 gcgaattata aattatctat tgttatagat taataataaa actagcagat ggtaaaaata
    26761 ctaat
//
LOCUS       DADVXK010000029        26098 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.029, whole genome shotgun sequence.
ACCESSION   DADVXK010000029 DADVXK010000000
VERSION     DADVXK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.029"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..115)
                     /locus_tag="KB909_001139"
     CDS             complement(<1..115)
                     /locus_tag="KB909_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002607271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6837187.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINE"
     gene            complement(457..1092)
                     /locus_tag="KB909_001140"
     CDS             complement(457..1092)
                     /locus_tag="KB909_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6837188.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            1604..2746
                     /locus_tag="KB909_001141"
     CDS             1604..2746
                     /locus_tag="KB909_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBB6837189.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            2739..2945
                     /locus_tag="KB909_001142"
     CDS             2739..2945
                     /locus_tag="KB909_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBB6837190.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            3024..4217
                     /locus_tag="KB909_001143"
     CDS             3024..4217
                     /locus_tag="KB909_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6837191.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            4422..5561
                     /locus_tag="KB909_001144"
     CDS             4422..5561
                     /locus_tag="KB909_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBB6837192.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5554..6354
                     /locus_tag="KB909_001145"
     CDS             5554..6354
                     /locus_tag="KB909_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6837193.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6354..7181
                     /locus_tag="KB909_001146"
     CDS             6354..7181
                     /locus_tag="KB909_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6837194.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7159..7893
                     /locus_tag="KB909_001147"
     CDS             7159..7893
                     /locus_tag="KB909_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6837195.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            7993..8859
                     /gene="rfbA"
                     /locus_tag="KB909_001148"
     CDS             7993..8859
                     /gene="rfbA"
                     /locus_tag="KB909_001148"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBB6837196.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            8873..9445
                     /gene="rfbC"
                     /locus_tag="KB909_001149"
     CDS             8873..9445
                     /gene="rfbC"
                     /locus_tag="KB909_001149"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBB6837197.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9467..10495
                     /gene="rfbB"
                     /locus_tag="KB909_001150"
     CDS             9467..10495
                     /gene="rfbB"
                     /locus_tag="KB909_001150"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBB6837198.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10593..11444
                     /gene="rfbD"
                     /locus_tag="KB909_001151"
     CDS             10593..11444
                     /gene="rfbD"
                     /locus_tag="KB909_001151"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBB6837199.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11478..13511
                     /locus_tag="KB909_001152"
     CDS             11478..13511
                     /locus_tag="KB909_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837200.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13555..14835
                     /locus_tag="KB909_001153"
     CDS             13555..14835
                     /locus_tag="KB909_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBB6837201.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            15045..15851
                     /locus_tag="KB909_001154"
     CDS             15045..15851
                     /locus_tag="KB909_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837202.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            15863..17083
                     /locus_tag="KB909_001155"
     CDS             15863..17083
                     /locus_tag="KB909_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837203.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17073..18659
                     /locus_tag="KB909_001156"
     CDS             17073..18659
                     /locus_tag="KB909_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6837204.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            18698..20836
                     /locus_tag="KB909_001157"
     CDS             18698..20836
                     /locus_tag="KB909_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6837205.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21204..22187)
                     /locus_tag="KB909_001158"
     CDS             complement(21204..22187)
                     /locus_tag="KB909_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBB6837206.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            22565..23956
                     /locus_tag="KB909_001159"
     CDS             22565..23956
                     /locus_tag="KB909_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6837207.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            23972..25012
                     /locus_tag="KB909_001160"
     CDS             23972..25012
                     /locus_tag="KB909_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6837208.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            25031..>26098
                     /locus_tag="KB909_001161"
     CDS             25031..>26098
                     /locus_tag="KB909_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBB6837209.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESI"
BASE COUNT         8454 a         4403 c         5331 g         7910 t
ORIGIN      
        1 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
       61 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
      121 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
      181 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
      241 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
      301 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
      361 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
      421 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
      481 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
      541 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
      601 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
      661 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
      721 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
      781 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
      841 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
      901 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
      961 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     1021 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     1081 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     1141 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     1201 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     1261 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     1321 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     1381 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     1441 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     1501 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     1561 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     1621 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     1681 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     1741 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     1801 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     1861 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     1921 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     1981 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     2041 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     2101 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     2161 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     2221 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     2281 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     2341 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     2401 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
     2461 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
     2521 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
     2581 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
     2641 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
     2701 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
     2761 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
     2821 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
     2881 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
     2941 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
     3001 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
     3061 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
     3121 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
     3181 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
     3241 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
     3301 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
     3361 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
     3421 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
     3481 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
     3541 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
     3601 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
     3661 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
     3721 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
     3781 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
     3841 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
     3901 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
     3961 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
     4021 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
     4081 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
     4141 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
     4201 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
     4261 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
     4321 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
     4381 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
     4441 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
     4501 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
     4561 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
     4621 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
     4681 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
     4741 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
     4801 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
     4861 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
     4921 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
     4981 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
     5041 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
     5101 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
     5161 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
     5221 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
     5281 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
     5341 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
     5401 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
     5461 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
     5521 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
     5581 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
     5641 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
     5701 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
     5761 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
     5821 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
     5881 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
     5941 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
     6001 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
     6061 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
     6121 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
     6181 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
     6241 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
     6301 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
     6361 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
     6421 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
     6481 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
     6541 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
     6601 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
     6661 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
     6721 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
     6781 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
     6841 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
     6901 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
     6961 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
     7021 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
     7081 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
     7141 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
     7201 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
     7261 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
     7321 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
     7381 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
     7441 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
     7501 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
     7561 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
     7621 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
     7681 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
     7741 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
     7801 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
     7861 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
     7921 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
     7981 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
     8041 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
     8101 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
     8161 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
     8221 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
     8281 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
     8341 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
     8401 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
     8461 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
     8521 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
     8581 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
     8641 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
     8701 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
     8761 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
     8821 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
     8881 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
     8941 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
     9001 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
     9061 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
     9121 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
     9181 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
     9241 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
     9301 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
     9361 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
     9421 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
     9481 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
     9541 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
     9601 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
     9661 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
     9721 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
     9781 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
     9841 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
     9901 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
     9961 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    10021 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    10081 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    10141 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    10201 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    10261 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    10321 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    10381 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    10441 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    10501 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    10561 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    10621 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    10681 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    10741 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    10801 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    10861 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    10921 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    10981 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    11041 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    11101 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    11161 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    11221 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    11281 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    11341 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    11401 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    11461 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    11521 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    11581 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    11641 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    11701 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    11761 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    11821 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    11881 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    11941 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    12001 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    12061 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    12121 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    12181 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    12241 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    12301 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    12361 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    12421 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    12481 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    12541 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    12601 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    12661 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    12721 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    12781 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    12841 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    12901 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    12961 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    13021 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    13081 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    13141 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    13201 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    13261 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    13321 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    13381 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    13441 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    13501 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    13561 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    13621 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    13681 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    13741 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    13801 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    13861 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    13921 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    13981 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    14041 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    14101 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    14161 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    14221 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    14281 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    14341 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    14401 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    14461 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    14521 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    14581 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    14641 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    14701 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    14761 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    14821 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    14881 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    14941 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    15001 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    15061 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    15121 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    15181 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    15241 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    15301 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    15361 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    15421 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    15481 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    15541 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    15601 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    15661 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    15721 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    15781 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    15841 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    15901 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    15961 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    16021 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    16081 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    16141 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    16201 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    16261 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    16321 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    16381 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    16441 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    16501 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    16561 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    16621 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    16681 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    16741 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    16801 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    16861 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    16921 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    16981 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    17041 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    17101 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    17161 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    17221 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    17281 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    17341 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    17401 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    17461 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    17521 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    17581 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    17641 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    17701 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    17761 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    17821 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    17881 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    17941 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    18001 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    18061 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    18121 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    18181 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    18241 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    18301 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    18361 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    18421 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    18481 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    18541 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    18601 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    18661 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    18721 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    18781 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    18841 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    18901 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    18961 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    19021 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    19081 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    19141 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    19201 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    19261 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    19321 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    19381 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    19441 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    19501 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    19561 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    19621 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    19681 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    19741 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    19801 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    19861 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    19921 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    19981 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    20041 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    20101 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    20161 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    20221 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    20281 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    20341 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    20401 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    20461 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    20521 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    20581 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    20641 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    20701 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    20761 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    20821 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    20881 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    20941 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    21001 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    21061 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    21121 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    21181 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    21241 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    21301 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    21361 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    21421 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    21481 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    21541 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    21601 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    21661 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    21721 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    21781 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    21841 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    21901 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    21961 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    22021 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    22081 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    22141 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    22201 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    22261 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    22321 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    22381 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    22441 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    22501 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    22561 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    22621 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    22681 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    22741 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    22801 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    22861 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    22921 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    22981 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    23041 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    23101 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    23161 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    23221 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    23281 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    23341 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    23401 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    23461 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    23521 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    23581 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    23641 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    23701 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    23761 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    23821 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcctc
    23881 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    23941 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    24001 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    24061 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    24121 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    24181 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    24241 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    24301 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    24361 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    24421 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    24481 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    24541 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    24601 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    24661 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    24721 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    24781 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    24841 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    24901 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    24961 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    25021 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    25081 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    25141 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    25201 ccgtattttt gttgtaccta atcctaagaa aaatattttt aaatatttaa tagaagtgaa
    25261 taagttacta aaaaaagaat ctttttctat agttcacaat caggtttatt ttggcggggg
    25321 aattaattta tggttagcca aaaagaatgg aatcagacag agaattgctc atagccatgc
    25381 aactgaagat ggaaaatctc aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa
    25441 attgttgtta caaaatgcaa cagactacct tgccgttagt caagaagctg gtgaaagtct
    25501 gtttcaaaac cacccctttg agatagttca taatggtatt gatttagagc tttatagtaa
    25561 aaattcagaa gctaaggtta ataagagaaa agaattggat atctcaatga gtacttttgt
    25621 tgtgggaaac attggacgat tagagaaaca aaaaaatcaa tcttatttgt tagagatttt
    25681 tttagaaata ctaaaaatga attctgattc ttacttgatt ttagtaggtg aagggtcact
    25741 tagaaataaa ctgaaagcca aagcagtaga attggatata gagaaaagag taaaattttt
    25801 aggagaaaga aacgatattc ccgagttatt atctgtgatg gatgtttttg taatgccttc
    25861 tctttatgaa ggtctgccaa tggttggatt agaagcacaa gcagcaaaat taaaattagt
    25921 cttagcagat actatttcca aagatacaaa gttaacaaat aatgtggatt ttgtatcatt
    25981 agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat
    26041 aacacaagaa ctaaagagtt atgatgtttc gtacactact gaacaaatgg agagtata
//
LOCUS       DADVXK010000030        24980 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.030, whole genome shotgun sequence.
ACCESSION   DADVXK010000030 DADVXK010000000
VERSION     DADVXK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.030"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..2131)
                     /locus_tag="KB909_001162"
     CDS             complement(<1..2131)
                     /locus_tag="KB909_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6837210.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWM"
     gene            complement(2128..2832)
                     /locus_tag="KB909_001163"
     CDS             complement(2128..2832)
                     /locus_tag="KB909_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6837211.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2844..5153)
                     /locus_tag="KB909_001164"
     CDS             complement(2844..5153)
                     /locus_tag="KB909_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6837212.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5348..5812)
                     /locus_tag="KB909_001165"
     CDS             complement(5348..5812)
                     /locus_tag="KB909_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837213.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5812..6438)
                     /locus_tag="KB909_001166"
     CDS             complement(5812..6438)
                     /locus_tag="KB909_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6837214.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6445..6810)
                     /locus_tag="KB909_001167"
     CDS             complement(6445..6810)
                     /locus_tag="KB909_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBB6837215.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6800..7138)
                     /locus_tag="KB909_001168"
     CDS             complement(6800..7138)
                     /locus_tag="KB909_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837216.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(7128..7454)
                     /locus_tag="KB909_001169"
     CDS             complement(7128..7454)
                     /locus_tag="KB909_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6837217.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7435..7713)
                     /locus_tag="KB909_001170"
     CDS             complement(7435..7713)
                     /locus_tag="KB909_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6837218.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7715..9079)
                     /locus_tag="KB909_001171"
     CDS             complement(7715..9079)
                     /locus_tag="KB909_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6837219.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(9092..9661)
                     /locus_tag="KB909_001172"
     CDS             complement(9092..9661)
                     /locus_tag="KB909_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBB6837220.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9633..10820)
                     /locus_tag="KB909_001173"
     CDS             complement(9633..10820)
                     /locus_tag="KB909_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6837221.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10884..12611)
                     /locus_tag="KB909_001174"
     CDS             complement(10884..12611)
                     /locus_tag="KB909_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6837222.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12608..13060)
                     /locus_tag="KB909_001175"
     CDS             complement(12608..13060)
                     /locus_tag="KB909_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBB6837223.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(13172..13552)
                     /locus_tag="KB909_001176"
     CDS             complement(13172..13552)
                     /locus_tag="KB909_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6837224.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13549..13935)
                     /locus_tag="KB909_001177"
     CDS             complement(13549..13935)
                     /locus_tag="KB909_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837225.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13937..14215)
                     /locus_tag="KB909_001178"
     CDS             complement(13937..14215)
                     /locus_tag="KB909_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837226.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            14263..14991
                     /locus_tag="KB909_001179"
     CDS             14263..14991
                     /locus_tag="KB909_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBB6837227.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(15122..15598)
                     /locus_tag="KB909_001180"
     CDS             complement(15122..15598)
                     /locus_tag="KB909_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBB6837228.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15558..15905)
                     /locus_tag="KB909_001181"
     CDS             complement(15558..15905)
                     /locus_tag="KB909_001181"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837229.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15892..16077)
                     /locus_tag="KB909_001182"
     CDS             complement(15892..16077)
                     /locus_tag="KB909_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837230.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(16078..16350)
                     /locus_tag="KB909_001183"
     CDS             complement(16078..16350)
                     /locus_tag="KB909_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBB6837231.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16347..16550)
                     /locus_tag="KB909_001184"
     CDS             complement(16347..16550)
                     /locus_tag="KB909_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837232.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16675..16887
                     /locus_tag="KB909_001185"
     CDS             16675..16887
                     /locus_tag="KB909_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837233.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16920..17114)
                     /locus_tag="KB909_001186"
     CDS             complement(16920..17114)
                     /locus_tag="KB909_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837234.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(17127..17309)
                     /locus_tag="KB909_001187"
     CDS             complement(17127..17309)
                     /locus_tag="KB909_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837235.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17306..17446)
                     /locus_tag="KB909_001188"
     CDS             complement(17306..17446)
                     /locus_tag="KB909_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837236.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17936..18301)
                     /locus_tag="KB909_001189"
     CDS             complement(17936..18301)
                     /locus_tag="KB909_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837237.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18341..18643)
                     /locus_tag="KB909_001190"
     CDS             complement(18341..18643)
                     /locus_tag="KB909_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6837238.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18643..18942)
                     /locus_tag="KB909_001191"
     CDS             complement(18643..18942)
                     /locus_tag="KB909_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837239.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18935..19099)
                     /locus_tag="KB909_001192"
     CDS             complement(18935..19099)
                     /locus_tag="KB909_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837240.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(19105..19374)
                     /locus_tag="KB909_001193"
     CDS             complement(19105..19374)
                     /locus_tag="KB909_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837241.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19386..20135)
                     /locus_tag="KB909_001194"
     CDS             complement(19386..20135)
                     /locus_tag="KB909_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837242.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(20132..20824)
                     /locus_tag="KB909_001195"
     CDS             complement(20132..20824)
                     /locus_tag="KB909_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837243.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            complement(20830..21501)
                     /locus_tag="KB909_001196"
     CDS             complement(20830..21501)
                     /locus_tag="KB909_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6837244.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(21494..21835)
                     /locus_tag="KB909_001197"
     CDS             complement(21494..21835)
                     /locus_tag="KB909_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837245.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(22013..22711)
                     /locus_tag="KB909_001198"
     CDS             complement(22013..22711)
                     /locus_tag="KB909_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6837246.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            22798..23268
                     /locus_tag="KB909_001199"
     CDS             22798..23268
                     /locus_tag="KB909_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837247.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(23311..23490)
                     /locus_tag="KB909_001200"
     CDS             complement(23311..23490)
                     /locus_tag="KB909_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837248.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(23477..23815)
                     /locus_tag="KB909_001201"
     CDS             complement(23477..23815)
                     /locus_tag="KB909_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBB6837249.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(23831..24034)
                     /locus_tag="KB909_001202"
     CDS             complement(23831..24034)
                     /locus_tag="KB909_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837250.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(24049..24825)
                     /locus_tag="KB909_001203"
     CDS             complement(24049..24825)
                     /locus_tag="KB909_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBB6837251.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
BASE COUNT         6942 a         5236 c         3855 g         8947 t
ORIGIN      
        1 ccatccattg tccatttgta aatgtccaaa taagcaatcg aacttgtgca tctaagctcg
       61 ttattggttc tttaatacct gcagcattaa ataagttttg aacataaact tttccatccc
      121 atgttgctgg accaacaaga ggatatgaag aaccatccca ctgaactaat ccgtatgctg
      181 gtccacctat ttgaacagta tcaggatcaa aagttcctcc tgtttcttgt tgaatgttcc
      241 ccaatattcc acatgcagat tgtttcgtaa atccgttatt acacaaaata tcgtatattc
      301 tccaagctct cttttctgca tctgttttta attcatcagg atacccacca ggtgtttctc
      361 ctccgccaga tggaccgcca ttttgtcctg gtatcacttc tttacctcta acagtaagtt
      421 ttccctgaat atctaaatca ccgaaataat atgcttttcc gtttcctaat aacacaaatc
      481 ctttttctgc agttggagaa attaaaatgt attttccatc gccatttgta cgtattacca
      541 aagaattttc ctcaagaggt gtaggtgtta cagcatttgg aaatggattt cctgctgaat
      601 ctgttgttcc gatcgttcca atggattctt ttctattcca gaattccata ccttttttgg
      661 ttagctccat gatttttttg ttttcattcc aaatttgaag cgtgcctttt acaagtttta
      721 acacatcacc ataagcatta aaggaagttt cgaatacttc tgcatttatt gttcctactt
      781 tgatgaagtc agcaacaatt tctccttttg atgtgatagc aataccgaac gggccattta
      841 ctccgttgtc tgaataacct aagccattta aattccaacg ccacactcgc tttgcattcg
      901 ccacatttgg agtatccatg ataagaatct ctgatggagc tttttctgga cgaaaaacga
      961 catgcccacc agaattacca gtgatccatg ccgtcgcatt caacacattt tgaactaacg
     1021 tttctgttcg attgtcgatt ttctttttca attcttgtgc ttgagtattt actgccgaag
     1081 tgtacagtga taaatcatta cctaaaacaa tatccttata tttcccaagc gttgggaaat
     1141 aagtgtattc gaccatacgc tcttttatct cgatatctag ctctttcgcc ctaacatgag
     1201 cgacatcacc aaagtgtaaa gacgctagct cttgatacat gtcaccgtat tcgagtgtgt
     1261 gttccaacgc caccatactg actgtatgag tagcttttgg ctcatggata cgatcattgt
     1321 caaataaggt tttgccccat ttgatcaatt catcaactgt tttacaatct ccgttttcac
     1381 gtttggcaat acgtcgattc tcgttggtta ctccatcaat ttctaaataa ccatattcga
     1441 taggttcttt gtcttcatca taatcgttat caggaacacc gccaaccaaa tacaaactat
     1501 tgacaattga ttcttcatca atttcttctt cgattgcttc taaattgatg ccaaaatcaa
     1561 tccgaaaacc attatctgat ccaatctgtt ttaccagttt caaatcatag ttatccatat
     1621 caagttccgc gctagtcacg ccagtcaaat tttgattacc gttatttgaa ccaatgattg
     1681 cttcaactgg cgcgacttgt cttgctgtaa attggtgcgt tgtccctaca ttcgaaagat
     1741 agttaaattt ttgatcaaat gccaaactgt ttttaagatt ggtcatgatc tgagacccat
     1801 tgccgttatc cgtaaacgac ttgacaataa agttcttatt ggccataaaa ccaatatgcc
     1861 gagctgttac agaaacggag gtcaaattct ttttgacatt ataaatttca aaatattgcc
     1921 atgatccatc tggtaccttc gcttttataa aatttccttt ttttaaataa gagcgatact
     1981 gtccgcttct tgaatagtta ccataaaaac gatattggcc attcagcaca cgattgattt
     2041 ctggcaaatc ttcccaatca actaacgacg ctccgttcac gctcaaatca tctggcattt
     2101 ttttataagc ataaataaat tcttgcgtca cagatacaca ctcctattcc aaaaccgcac
     2161 ttctttaaat tttccggata tttttacctg attccattca ggctgcaata ctggccaatc
     2221 accacgcgta aataaattca aaccttcttg tattgctttt ccaagctgag tatcaaccac
     2281 gattgttgca gctaacgtat taagtattgt taggctttta tcaccgacag cgatcgttat
     2341 atctcctccg ttcgattcta tttccagata gggatgtgca atttcgtcac catgatcaaa
     2401 aatatccata acactagaat gaaaaatttt aggtgcttca ccgatttttc ttttgagtgg
     2461 ctgacaacga aaagtaacat cgaatgtata aaagaagccc cactcgtttt cgaaagggac
     2521 ttctttatcc atgctgcaga tagcctctag atacttgtct ggatcattat gtgtgattaa
     2581 ttggctttta ccagtgagcc atcgtttgac ttctctcagt ttcgaatgtg gaatagtgat
     2641 cccttctatt tccaaatcaa aaggttcata gtcatcaaac gtctccgtca attctccgct
     2701 tcggccctga atcgtgtaag tttcgtatcg cttgttcggc ataatatctg gaagctctgc
     2761 ctcaatgatg caattcatat caattactgc attccgattt ttccaaataa aatttggttc
     2821 atctggattc ataaattgtc gactcaaata ggaacacctc ccaaatcacg aatagcctgt
     2881 ttgtttgctt tagcaaattt acgattcata cgatctaact cagatggatt gtttgcatcg
     2941 actttgccaa tgtgtatatg ctgttcaatg ctacctccag aaactcttcc actgatccct
     3001 ttgcgttttt cttcgtctga taatggagta actgtggttt taccattctt ggcagtcagt
     3061 aactcaggtc cagcttcacc aacaatcgct tgtccattga ttagatgacc gccttgtgct
     3121 aaataaggca gttttgaaat agaaaatgat tttccaccta caccaggaac ccattttggt
     3181 atctttatat tattcaatcc accaataaat ccattgatca atccaatcat ggcattaata
     3241 ggagctttcc ctacagcaac aataccatcg aaaatacctc caaaaatatc aactagacct
     3301 tgccatgctt ttgaccaatt ccctgtaaat actccagtga taaaatctag aaaaccactg
     3361 aaaattcgtt ttccagcatt ataaaaatta ttgaaatttg ctataacacc atcgaaaaat
     3421 ccaccaaaat aaccacttaa aaaattaaat atttcaacag ctacatctga aacacctttg
     3481 aagaaagaat tcactccatc atgaaaccat ttaacgttat tatatgccca aattagtcca
     3541 gtaactaatg cgccaatagc tataactgct aatgcaaacc agcctcccga cattccaaat
     3601 aaaccagcaa gtccttgcca aactcctata aaacttttaa cttccccaac gatttttgta
     3661 acagatccca taagtgaacc aagaacgatt agtactggtc caactgctgc cgctatacca
     3721 gcaattgtta tgatccaatt ctttgtatct tgatctagag acccccacca tttagagaat
     3781 tcctgtaata aggaagttgc tttttcaaaa aaaggcaaaa ggcttacttg gactgcttca
     3841 cctacgtcag ccattgctaa ttttgcattg ttcatagctt gatcggcttg atcaattggg
     3901 tcgagagtag catcgaatgt gtctcctaca gctcccccac tttctccagc agtttttgct
     3961 aaatcttcca ggttcaaagt acctctacga attgcatcgg ccattctagg accgccttta
     4021 gtcccgaata cttctgctgc tgcattgatg gcttctgttt cagaacctgc attttttacc
     4081 ttgtcttgta gttcttctag tccttgactt aaagattttc cgtctttcgc ataagccact
     4141 gttgctttag ataaactact taaagctgcg cttgaatcaa caccagattg ctcaaattgt
     4201 ccaagtaaag tgaccccttc accaaagctc aaccctaatt gtttaatttg tggtgcgcca
     4261 tcaattgctt tttgcatcaa gtcgtctaca gattgaccag tattctgcga tgttttcgtt
     4321 gttacatcaa ggacagaatt caaatcatca tattctagtc cataagcatc aatagcttgt
     4381 cgagcagata ttgctgattg cgaaacatct gtatcattga tttcagcgta ctgtaggaga
     4441 taattggttg aatcttccag ttttttatcc atgaatccaa attgtgtatt tacctcacca
     4501 atagcttccc caaccgtttg taaaggtaaa tgagtatttg aaccaacgtt tttgaaagac
     4561 tgtgaaagtc tatcagcttg atcacctgtt gctccggttt ttgtaatgat ggtatcaagt
     4621 gcctcgtcaa cttcaccaaa tgctgcaagt cctgctgctc ctgccgctac aataggcgcg
     4681 gttactccaa cagacatttt ttcaccaacg ccttttactt tctcacctgt ttcttcgatt
     4741 ttctggagtt tttttgctgt atcaacagaa acgtcacctt gttctttaag tgcatcgttc
     4801 gtctgttcta atgctgtacg aagtttattt tctccggttt cagaattgag taattgttta
     4861 taaagttttt ctgattcagc agaatattca ccggtttctt tgacagattt ttcatattcc
     4921 tctctcagca tttgagatcg ttgttcagcc aatcctaatt gtttttctaa tttttgttta
     4981 gccgctcgca atttttctgt ttgagttgca tccttgtcca tcgcagacac ttggtttttg
     5041 tactcggcag cggctaagtt catttctttg ttgatttctt tgattgtttt cgaataactg
     5101 acttcgccat tcgttttaaa attaagaacg acatcagatt ctttaccagc catttatctt
     5161 agcgctcctt tctaccacca aggcgattta tccatagtta cagattgagg tggttcaaaa
     5221 tcggtgtttt gttgtaacca ctgtaaataa gatttgagcc acaagttagg tgtagacttt
     5281 aaaaagaaac tctcactcca attcaataga gtgagagcaa cgtaaatata aaaactccaa
     5341 ggagttccta tctcttccga ttctttttgt ttttctttct ttttgcttgc gctttttgaa
     5401 agtcttgtgg cttcttggat ttttttaggt cttccacctg aaatgtctgg ctagcaaaaa
     5461 tttccataca ggtactataa gcagacaaca cctctccact cattcccaaa aatttgaaaa
     5521 tagtttctgg atcttcctct aaaccaccag tacgcagcat ggcataaatc aaggcacgca
     5581 tgatttttag atcactaggc gataagttag cagaagaaat ttgtccttct tttttagata
     5641 gcatggcgtt catatcagat tcaaattgcg aataatctcc accatacaca tctgctataa
     5701 attccatcgt ttgcatagta aatgaaatag ggaattctgc gccttgaata attacaacag
     5761 cagaattttt taagtcttca acgtgaattc cataatcaga taaccgagcc attaacccgc
     5821 acctccaact ttagccaatg ttttccactg ttcttcatcg tatacaggtt gagcaatgaa
     5881 tttattaaat aattctagag aagctccgtc tctatttgaa tcaaaacttg catacatcac
     5941 attattgtat ttcagtccga tggaaaccag atttgcagtt acatcgtcaa tttttgtttc
     6001 ttcctctgca gtggcatact cttcgtcaat cacattggat agttgtgtat taggatacca
     6061 aactgctttt ttaccgccat tttcaatatt tccaataaat ccaaaggcga agtacggaaa
     6121 ttctcgtgcg gtatttttgc taaacgttac tccgctttta gcaactaatc ctttgatttc
     6181 atccatcact tctatcggaa tacccacgtg atccaacgca agttcatgtt ttgtttctcg
     6241 cgacacacga cgaaacattt tgctggatgc ccatttttct aatgctgttc cattcccttt
     6301 gacaccgatt tttgtggcaa ttggcaatcg taaaacttca ctataagtcg gtgcagttcc
     6361 aacagaatct ggcgttgcca tcatcgcaat taaaatgtcg tccaatcctt caaaataaaa
     6421 agtatcttgt tttcccaatt aaaatcaccc ttcccataaa tcaagtattt ttctagtcat
     6481 aatttcttca attttttctt tgttttgttc atacgtacca cttgcaaaat gttgggcacg
     6541 ttgatttgtt gtgccatttt cggcaaagcg ccagtaaaag gccgtctctt caaattgaac
     6601 tttcacttga tcgttttcaa ctactacttt tatttgatcg cgcatatgtt tcttttttaa
     6661 gagcgactta ggaatattag gaagcaactg ctttagataa aagttagctg cttcttctaa
     6721 agattccaac gataattttt tcggatcaac ttttgaaagg tttcctaaat aatccgatat
     6781 ttcagaaaaa ccattcttat tacttggcat tttccacaca cctcacatat gtgtaatagt
     6841 tggttacggt atcgtcgttc tcatcacctt gtatacctgt aaaatctgaa tatggaatgc
     6901 cagcattttg cagcgcttgt tcaataacaa ctaaatcctg ttctgttcca agtgtaaaaa
     6961 aagagacttg gtaataaggt aattttttat agactttacc ggatgccatt tttttgctgt
     7021 tactcacatt tgagtacaca atgtatggat acatcgtccc taatctggct ttgtctctga
     7081 acactgctaa ctttgttgat ttcagcgctg ttttcaattc atcaaagcta atcgacataa
     7141 gctaaactca actccatttc tcttgcatcg ggattcgtat aaatgcgagt aatgttatac
     7201 gttacagaat caattttgag cgcacttaat ttctctgtga tggatttatc ccatctgact
     7261 ttaattcgtc tgacaacgtc tgtcttggct tgctgtgata aatatttttc ttgagaagtc
     7321 acaccgagtt cttcatagaa tattagacgc ttaaattcgt aaattgtagt tggacgatcg
     7381 tttccgtctg ttcctgtttt gatgtctagc aattcggctt tccatctgag attattagtc
     7441 tgtctcttcg gcattttgaa tcgctccttg cacgataaat ggcgtcatgg cattcatagc
     7501 tttgtcgagt tcatcctctg aaactctata ttcataggca atgccggcaa ccatcaaaat
     7561 aagatattct tgttggccac cagttgctgt tttgacataa tcttttgcca tatttaaata
     7621 aaaagagagc aaagaatcat ccatgccctc ttcaaaatga atatgtgatt tgaatttttc
     7681 ctctaaagac aattctttag tttgctcttc catcttaacc accaactggt tttgtaattt
     7741 cgtagcgata tactgccggt tcaaatggag aataaaccaa ttgaccatct agcaagttgt
     7801 aaatttggaa tccaatttga tttttaccag agaatttttc aacaagtttt tgaatttcca
     7861 aggcaccaat aacttcttga attttaaatg cagaaaaatc gccaaaatat aaaactggcg
     7921 tgtctggttc acccttttta tctgctgcat ctgtccaatc cacaggatag ccaactaatt
     7981 ggtaaccaat tccaccttct gcttgtgtga atggccgcaa caaaggaaat ccatcatctg
     8041 ttttcatttt ttcaatggca gtcaaagcag ctcgattaat aataaagcgt ccctttttca
     8101 tcacttctgt cactggtgta tttttaaatt cgattaatgc atcatataat ttttgcccag
     8161 cacctgaagc agttagatct aaaggttttt taaatgctac agcctttttg gctaatgcac
     8221 caggattttc atttccagcg tcatcaccat tgaacatata attgatttct ttacgcacat
     8281 aagctttttt caattcttcc acaacaatat cttcaactgg aacaccagac atttttaata
     8341 attttttagt tactgttgcc aaagcatcga attcggcagg attaagcaaa atttcatcaa
     8401 actgaatagc tgtttcagca atatcagttg aacgctcttt cttgtttaca ttcgcatctg
     8461 ctttcttcac aagaattgga tatttgacat ctcctgatgt tcgcaccact gttccgtatt
     8521 tacgaagtaa attttcttct tgagcataag taataacttc agatgcaatt acttctggga
     8581 cagtaactga accgttgcca gcttcaatcc ctaaagctcg agcttctgct tcagaaatat
     8641 ttccagctac aaaattagca aatgcttttc gtagttgttg atctttttgt ttcttggtca
     8701 tttttgcacg tgcctccaat ccgttcttaa ttgatccaag taatccatct cgttgctgtt
     8761 gagtaatcat tccagaacga ttttctgaac tatcttcact gtctgaatct tcttcttgat
     8821 cgttgtcttc accagaacgg ctttcgtctg aatccgtact attcgattga tcatctgtat
     8881 tgtcgtctgt ttcatcagtt ccagaatctg cgcctaattc gtctttaatt ccgttcaatt
     8941 catcaataac actgtcaatt tcttctttca cggcttctaa atctgcttcg cgtaattctc
     9001 ctgattcaac tttttcacgt aattcagtca atcgttgctc acgacgtgcc ttcatttttt
     9061 tcaataattc tttatccatg tatttttcct cctacgcttc tagcgcttga ttaatttttt
     9121 tgattaattt ttttctttct tcgacgtttt tttctaattc atcacgactt cttaatgcag
     9181 cttctgtatc ttcgtatgct ggcaaaggca caatagaaac ctcgtataat tccacttcat
     9241 ggattgttcg aagcattggt tcagaattgt agtcccacgt ttcttcagtc ggcacaaaac
     9301 caaaactaca ttggttgatg tctcctcgtt ccatagattt aactaagtcc cttgctaccg
     9361 ttgtgtccgg taaatcaact tcgaatttca aaccacgttc atcttcttca aggcgaaggg
     9421 ttccgctttt agtacgtcct agcacattgg accaatcgtg attgaacaaa caacgaacat
     9481 ccgaattact aattgccttt gagaatgcac caggaacaat cacttcgctt aagtcatccc
     9541 ataaaagtgt ttgactgttg aatacagcag cgtagccgct aatggtcctc gtatgagttt
     9601 cttcatcgga acgtgttgaa agattggtga tgtcaatcgt gcgaatttcc ttcttcttca
     9661 tttccatcac ctcctttcaa gtcttgatca ttcgttggta aggaatcatc tgttgcattt
     9721 ttctggccaa tcctagataa gtcatttgaa atatagatag cttgtgtttc tggagtattc
     9781 tgtttaggaa aaccaagcat ttctgccacg ttatctggac ttgtaatccc ggtacgaacg
     9841 atgttgtagc caatatttgt ttttgttgag taaggaacaa aatccaaaat attaattttc
     9901 cattccactc tatagccaga attaggcata aaaaaaagag cggtgtaatg ttcgctcttg
     9961 tttttcaata ttggtttgat tgctttgttg tgcagataca tcatcgcttt ttcaatatct
    10021 gtcttcatca gcgattgata cgtatcaaca ttgattccta gaaattttcc taagtctttt
    10081 ttgtaaacac ctaaataatt caaaattgcc gcgtcatcaa caggactttt taatgtctcg
    10141 atggaatatc cttttcccaa aggaatcatc ttaacagaat gatcactctc attttgcgtt
    10201 ccttccagtt gatccaatat agctttgaca atttttgttt gggcgctatt atttggattg
    10261 atgtgggcgt ctagtttaag catgaacgca agtaaaccgc ctttagtata tttgtccgtc
    10321 aaaacttttt cagcgctcag aacgccttct agagtgtttc ttgcaagatc aattattcca
    10381 gcacctttta atgaatcagt tccgatgttc ttaatgtgtc gaatcatttg accaggtatt
    10441 ttttgaccat tcatttcaaa ttcttcttga agtcgttcat tgattttagt tgttacaccg
    10501 tacgccaaat gaagctgatc cctatccgtt aatgggaatg tctcaccatt gatcaataaa
    10561 gtatttgttt ccaatttggt aaattcgaat cctgtcaaat aatcattggg actcttcaaa
    10621 atatttagta agtgatgatc tttgacttcg ttgccgtcgg gaccaataac aattggtgtg
    10681 gccaatgcca cctgattaga tatgtcttga actaattcat aaacatcaga agattccatg
    10741 atagatgaat ccgtcacata tctttgacca taacgtgtgt agtgtccaaa aatatcctcg
    10801 atatatccac gtttttccat aaaagaatag actgcattcg ataaccgatc acgtaatttc
    10861 aatttttttc accgcctttc tatttatcta tagatggaac ttaggtaatc atctaactca
    10921 tctgaatcaa tatctgtcat ttgattcatc gtttccttat gaccacacaa aaacgccacg
    10981 aacccatcaa tctttttctt tgattgacgt ttacttggcg ctttttgtcc attgatgtta
    11041 gtaattgcta caacgttcaa agtgcaataa aggaataatg gattatcaaa ttgaattcgt
    11101 ttctcataaa acaaccgttc gacatcgtca aaaggagcat tcaatacttt aggatattga
    11161 gcaacttcaa cgcattccaa tcctaagttt tctaatttct caacaagttt gtcactcatc
    11221 gctggatcat aattcacttg ctgaatatca tataaattca tgcagtcctc tatgtactgc
    11281 aaaatctgat cttgatcaat catttttccg tcgcaaaatt caacgaaacc ttgttcagcc
    11341 aaatcactgt aaggaacatt atcttctttt tctcgaaact ctaaatcttc attcggaata
    11401 aaataaagtt gctttacttt aagaaccgct ttaccatctt catcccatgt tgggaagttt
    11461 aaagatacac aggtcaaatc tcgtgtacgt gataaatcta aaccgatata acatggttcg
    11521 ccacttaaat caccaagttc ttgtgtggta actaaacatg gctctacttg atcctgttca
    11581 aagaaattat ccgcgccgtt cacaaataca tccaagtgtt tcgttagaaa ttcagctttg
    11641 gaatgagctg accgttgcgc tgttttaaat gccgattcta aagcagataa atcgactgat
    11701 attccccagt taggattgca catttcccag acttttctat ccgtccaatc ataattttta
    11761 tttggctcat agattagaac aaagtttgaa tcattatcat cacgtttcaa cacttctttt
    11821 gcttcgcgat atacacgcat tccaacagac gacgaacctt tcccagcagt tgagatatta
    11881 aacatcaatg gctgtggtaa agatatctga gcagacttaa aattgtcata ctgttccatt
    11941 ttctcctgtt tatgcaattc atcgttcaat acaaaatatg gattggatcc ctcgatatta
    12001 tcaatattct tggtttgaac aataaattta tttgagtaag ccatatcttc atgaatatag
    12061 tcataagtaa tactagaaac agttcccttt ggccccctaa atattttagt tccttcaagt
    12121 aggattggat tgtttaagat tgtaactgca aaaggtttgg cagcatattg cgcttgagca
    12181 aaatcagatg cgcaagcata gcaatcaact gataacgccc cttctccgta cattgcatat
    12241 cctaatgaac cgacagcaat caatgtttta ccattctttt ttggaatctg gacataagcc
    12301 tcacgagtaa cgcgtacaat ttggcctttt tcattttctt taacccaacc ataaatccaa
    12361 gaataaataa atttttccca gggttctaaa agaaacggtt ttcccaccat ttctcctttt
    12421 gtgtgaacaa taaatgattc tacccaatcc atcatttcat tcgcgcgatc tacatcaaac
    12481 caaatatctt ttcttttttt ccactgatac cagcgatcta ttgctaaacg aacggtctta
    12541 ggatacttct taggtttctt tcttacttct tttgcaaata aatcagcata atttacacca
    12601 ggttcaatca tttttcagca cctgccttct tacgccattt atttctgtgc gctgctagtt
    12661 catctactgg ctttacttct gggcgtgtaa tttcttcatc ttttcttgcg gtcgatcctc
    12721 cagcaattag tctaccagtt tttgctttgt ttgttaatcc taataaatct agagctttca
    12781 tcttcttatc tgcccaagtt tctacttgtt gtgccaatgg atgttttgat tgattagtag
    12841 ctcctgattt attcgtgaat ttttgcgtct ccggaaatcc tttttccttc cacaataaat
    12901 atttgtgttg gtaaatttca aaaatatcca agtatgattc gattaatgga tcaagagtga
    12961 tggtgtacaa atcagacaaa ttcattattt ctaagatacg agctttttca gcacttactt
    13021 tttcatcaat aatcgcttta cgttgcgctt tagtcgtcat ttttgtatac accccccttt
    13081 gttttttgaa aaatttgacc taacgatgcg cgtgactccc cgctacccta tctccccacg
    13141 cgaaaaaatt ttgaaaatga ataggggggc ttcaattgaa atacgaagga aaaacttttt
    13201 tgtcttccgt ttcgttttca acaattggat gacattttga acataatagc atgagattgt
    13261 ttggatcaag cttaagcagt tcgttgtctt tgattggtac aatgtgatgg acgtgtgctc
    13321 tctttccaaa tatgaactga ccacaccgct gacaatgacc accttctctt tcataaataa
    13381 attgacgcat atctttccat gcttgcgttc gatagaatgg tttgttctca tgatgataaa
    13441 cagactttgc ttgctgcttc ttcttgcgtg atctgcttga tctcttgtgt tcagtacagt
    13501 agataccctt tgctattttg ttcgtgcatc cgtcaaactg acagtatttc attctacttc
    13561 acgaataaga tttatgatat cgccttttgc acggatagca ccaggaatat caataccatg
    13621 tttcttagca tatgcacgca attcttttgc agtcatattg tccagttcat ccgtatcttc
    13681 agtggactga tcattagtag cttcgtctcc atcaaaatta gcagcagtgt ttccatcgct
    13741 atcaagaatt tcactgctat gagctatgag ttcgccattg acagcaacaa atgatttgcc
    13801 atcactcaaa attccttttt cttcttttac ttcaaaattt ggttcttgat ctttcggaac
    13861 aactactgtc cttttctttt ctgaatccca atactctgtt ccactaatgg atgttctaat
    13921 tttgatcatt gccattttaa ttctctcctt tgtaatttgt acggattact tttgcgccca
    13981 ttcgctcata ccattcaatc gtttcctgca gattgggtag agtgtgtgac aataaagaaa
    14041 taactaacgt attcattcca gttctgtaat catcattctc cacttgcaca tgtgcatgat
    14101 taccattcca attttctctg tacggactat tctctgcttc aattgctttc ttataaactt
    14161 tagccaaact tgattctact tcaatactaa gtaccgcttc atgaaaatca ttcatttgtt
    14221 tactctccta tcagatattt tgtggtatga tttataaaaa agatgcgagg tgttttaatg
    14281 cttcaagaag ttaatattaa gtatcgtgat cgtcaaaata cagagacaat ttatttgcca
    14341 aatagttgtc cgcattgcgg aaatataatg actccgtatg tgtattttgg ggtttcatca
    14401 tatagtgcgt tcgataatga tagaatcttt ggcgtattag tacagtgtat aaatgatgag
    14461 tgcaacaaat tttatagttt acaatttata aatacgttta atgaagatga aggatattct
    14521 gaaaatattt taattaaaga ttattaccgt ccgccgatta aaatagattt accagaaaat
    14581 attgaaaaag tttctcctac atttgttgat atttatactc aagccacaca agctaaatct
    14641 gagcaattgg aacaaattgc tggagttggt tatagaaaag ctctagaatt tctaattaaa
    14701 gattatgcaa tatctaaaaa ttcagaggat gaagataaaa taaaaaaaat gttattaggt
    14761 aaaacaattg aaaattattt gaatgatttt cctaaactcc aaagattagc caaagctgct
    14821 acttggattg gtaatgatga aacgcactat gttcgtagac atactaataa agatgttcat
    14881 gatatggatg catttattaa atcagcagcg caatttatcg cggctgatta tgatgctgat
    14941 ttagctgatc aatttataaa tggaaataac tttatgccaa ctactaatta aaagaataaa
    15001 agagccacag ataccaatta ataaaacggt tgggatatct tggctctttc atattttttt
    15061 gacactaata gaatatcatg ctgctaacaa tgtttacgaa catttagtga acagtgtaat
    15121 tttagaataa agagagttgt tctttgtact tctcgctatt gtaaaaatca atttcgtttt
    15181 cttttttcaa tcggtcagct tgtctgtgtt catactcatc taaaaagttc aatgtctttc
    15241 taatttctgc atgtcgctgt ctgacatacg atgagctata cccaacagat tcagcaatat
    15301 cttctaagct catttgatca acatatttca tcttaacaat ttgattatcg ataccagaaa
    15361 agctatctat cagcaataac atttcttctt tttgctcgat caacaattcc aattcatttt
    15421 ctatcttttg gatattctct tctaaagaag aagttctcga attcttttcg atgcggacgt
    15481 ttgctaaatc accacagacc catcgattca attcaagctt acttttatta agattccact
    15541 ttaagtaaag aatctgctca tctagttctt ggtaatcttt taaccaatga aatctcacaa
    15601 acgccacccc ttatggtaga atagtattgc gctgctatct cgaaaggggt agctttttta
    15661 ttttttctta gccgttccat tctggattgc cttttgttcc aaacgtcgtt ttttcttctt
    15721 aatctttgat tttgtttttc ccatacaatt ctcctttccg aaaacacatt ttgttcgatt
    15781 tttaatacta aataaaagtt ggccagaatt tttcgttcgt ctttactcat ctttttttga
    15841 ataagattac tagcataaaa atagttagta ccacgaaaat gaacaggtaa atcaattacg
    15901 ttcaccttct tcatgccagt tatcagccac tagaatcttt gcgttagtgc cgccaccgtt
    15961 ttcttttttg tatttttcaa atgctttata agcagctgtt tttgatttat agatttttcc
    16021 ggaaccgact gggaacatcc atgtgccctc tgtgatagct aagatgtata ctttcattta
    16081 attcacccct ttaatcccca acactacata tccggacttc tgcatgtaat cagtaatata
    16141 agtgatctct gctttgtatg agtcaccagt gtaactaaat gttggtctcg ttagtccagg
    16201 taattcatgt ttaatgtatt ttttatattc acgtagtatt aactgatcac caactttgaa
    16261 gtcacgatca ttcttgcgga tctcgaattg tttgcgtccg ctcgtcactg cttcaaaata
    16321 ttctggtagt atttttagtt cgtggatcat tctgtttcct ccttcaaaat tcgctcatca
    16381 tcaaaaagtg aatctccaca aaatccttct cccaaatatt tatcgttcat gtataagtca
    16441 accaaatatt tgtgatctgc ttctcgatat tcattaatat taacgatctt tattttgtaa
    16501 acattacctt cgtcgctcac tatcttgaat tgttctctga ctttcaccac cgttcctcct
    16561 ctttttgaaa aaattttagt gtttttgtaa gaccccctaa atcagctttt ttatttgata
    16621 taatacttgt atcgattaat caaatcgaaa ttaaatttaa aaaggtgatt tatcatgaat
    16681 atcaacaatt tagtaaaact cgttgaacaa cgttttaaag aatcaggatt agaacaatta
    16741 aaaaaagata attctccaga attattttct aattttaccg aagacgacat tcctactctt
    16801 aaacaattaa aatattattc tgattattgg acgcaaactc gtgagaatga attaaattta
    16861 gaaaaactca ttattaaaaa gaaatagcaa ctccagccca cacggctggt tttttagttt
    16921 caacttccct ccttacgggt caaaatcatc ggttccggca taatctgatc atcctttagc
    16981 aacaaatcag gatatttttt ccttagcttc ttattgttcg tgtaagtttt caatagccat
    17041 tggttggctt cgcttttgct ttctccagaa aaataaattt tccctgtttg gatgcctgca
    17101 agttgaatca tcattttcac ctcaaatcaa attttttctg ctagatggag caaaagcaat
    17161 ccgacatcaa gaatcttttg acccattatt tcagctactt tgctcggctt aactccttga
    17221 gaaaagagca agcgtgcttg ctctatctct tcgtgagtcc aaataaattt ggcttcctca
    17281 aggataatta ctggatcagt tgctctcatt gttcctctgg aaaaatgatg tcattcttat
    17341 gcttggacca ggtatctgca tatggaacaa agtattgtct agctaattcg atttgatcaa
    17401 ttaaagcagt ttctgataat tcatggtctg cagcaatttc attcatacta tcgccttcat
    17461 ctaaacagat aagaccgttg acgttatcga tttttacatt tgtgactgct tgactttctc
    17521 cacgctcata atattctaca gttgatactg atacatcagc ttcggagttt aattgcagaa
    17581 tctgttactg ccgggataat ttaatattct tttcataatt cacctttttt cctactgaca
    17641 tcgaatattt ttcatgttat gattagccgt gaaaggagag ctatattatg tgtttacaca
    17701 tgatgtcctt agctcattcg gttctttgga agcttttttg gaaataactc tcaggttctt
    17761 gacgcaaatc tcatttattc tttgaaacaa aaaacttcca ttttccgaga gctttggatc
    17821 acttcaaaag agatttgcat ttatatttct gtgaccttga gtcgcgtaaa gaaccttaca
    17881 gcaatggcgg caattccact ttcaggaaac cgcctttttt cattgatatt ggtggttagc
    17941 ggactaccca ttttctttcg gcagtgccaa accacaaatg atctgtgttg atgtttaggt
    18001 agttgtatac cagataagct aaatccaaag tgcctgcatc ttcaagacga caatattcca
    18061 aaaattctcc catagctgga cataaaaatc ctggagctat catatcccaa cagttaatag
    18121 tgcaaagaaa ttcgtttagc ttctgaacgt tttctttggt ttcacgaatt acaacatact
    18181 ccaattcttc tccgctggca gagcattcca aaacttcaaa ttgattaaga aatggtagaa
    18241 catatgcttc aaacatcaac attccatctt tctgtttttg cacttgtttt gcatcaatca
    18301 tgtctatcct cctattcagt tatttcttcc attaatggaa ttatttcagg tcactggact
    18361 taacgaaaac accattgacc atctttccag tccgaccttt gatttcgtca taagcaaaat
    18421 ccaagcactc gtataaatcc atatcatttt gcattgccaa gatgatcaag gttactacta
    18481 catcgccaat tccgtctctt aaaccatgtt catcttttct agctagagaa gcggcaactt
    18541 ccccgatttc ttcgaccgtt tttaacattt gcttgctgaa atccgcttga tccaatccct
    18601 tatcttttgc ccactgctct actttcgcga ttagttcgtc cattatttct cctccacata
    18661 cctaaactgt cttccttttg aatcaatcca taagctccta gctctatccc aaataatatt
    18721 tttgctcaga ccagtaattt cagataactg tttagcggta cccgttacta gaattcgatc
    18781 accatgccag attgcaatct ttctcggcgt tctccgtttg ggcttttcag tccacattga
    18841 tttaccgagc ttttggactt ctgcaactat ttttttatct tcctgccaat cttctgaata
    18901 agtcaattcg ataattcgct gcattgccgc tttcttatcc atcccgacat tctcctttca
    18961 gtaatttgag tacttgatca agtgcgctct cacgtccgcc atgaaatgtg ttgagccact
    19021 tgtcttcgta cgacacactt tgtcttaaag cttcttgatg cattaattcg atctgtgctg
    19081 taaatgtctt taggtccatc ttgtttacac ctgctcaagt tcattaagat gtttttgcaa
    19141 gcctttaaca caatcaatga atagtaattt ggtatatgct aaatttctta attgcgttcc
    19201 atcgatatag agtgcgaaat agtatctgag tttactccaa ctcgaacgat cattcttaat
    19261 tccttcaatt ccagcttctt cgagttgatc atatacgtct ctcaggacgt ctaattcctc
    19321 gcccttttta taattcgcta tttcattaat tagttctaga taatcgatct tcatttttcc
    19381 acctcttaga atggtgcttt tgattgtcta ttagctcgtt ctagcgcttt tttcttgaga
    19441 taggcttctt ggtcgattgc ccattcagga agcttctctc gtcttcctgt gcgcttgtat
    19501 ccactgcttg cgttcttagg ttcacttttt tctttccttg cccaacttcg aatagttgcc
    19561 aaatagtttt tataagtctt accagatgat tcacaatact ctgacagtcg ttcgattcgc
    19621 tcttggtaat cattagggaa ttctgttttg agtttctcca tctgctcatc tgacaaaaga
    19681 acatttttat actctccgta tttatgacgg acgggcttag ccttcgattt tttcgaaggc
    19741 ggtaactctc ttatatattc ttttgtatta ttaaatgtat tattaataga tgtattatta
    19801 tctttgactt tttcgtcaat aggggtattg cgtttttcgt caatagggta ttgattaatt
    19861 cgtaggtacc tattgattat ttgattggta ccctctttgt aaatgatttc ccgattcaag
    19921 tatccaaact taatcaaatc acttacccat cgcgatatgg tctctttatt cacaccatat
    19981 aaatctgcaa agtactcatt gcctgcccaa caaaagcctc tttcattaca caaggccgtt
    20041 atctctccgt ataacaactt agtatttggt ttaagtcttt tgtcgtacct tacgttggct
    20101 ggtataatcg cataataact tcgatgttct gtcatttttc ccctccaata tttaactttt
    20161 tgattgtttt ctggtttaat ttgatccctt tgatttgata tttatttttg aaattaatca
    20221 cacctatttt gtgcttctct gtgtgatgga ttctgcagag tgctgcaaat gtgtactctg
    20281 catgatcaac ttctttgcgc tttcgtcttc ctagcgcttt gtcaaagtga tcgatgtcag
    20341 ctcctgtttt gccacagatg cagcagactc tttttgtgat gcatttgtag aagtaatatt
    20401 cttgattcgc aggtaaaatc tcatagcctt ctttgaaagg aatatgatgt tcaaagatga
    20461 aatctaagat gatatttgct aagacattgg catcactcac agttgtattc gattcgtctt
    20521 tcaggcttat tttgcgccct gtgacacctt caaaacgaaa gtagaagaat tccttccaga
    20581 agtccgttgg catgcctgta tcgataaaaa tatcgcctat cagcgcatag atgaagtttc
    20641 gttgctgtac ggtgaaacgt ctaggatcaa taaaacgaat ttcaatgact cgatcaccat
    20701 cgtagccgtc atacatcgtc tttagtcgat caatgttcac ttcctcattg atggttgcgc
    20761 ttatgtcttt tcctttgaac tttttcagaa ccgctgaata tgaatcgatt aatggtttaa
    20821 acactcatat cacttcttat ctaattcttt tctcttagct gctattgctc gctccatcaa
    20881 ggcacattgc tcatagctta actgttcaat agtttcaacg ttatcagcta agagccctaa
    20941 tttatctgtc tgctcattaa catattcgat taaggttttg gtcatatctt tacccatctg
    21001 ctcattgaaa gcttctagaa tcgtctctag catgtttaat ttctttgtat cgattctagg
    21061 tggtgttgga atatcttccc cttgaaatac atataatccc agtccgtgta gagccaatgc
    21121 tttcacaaag catcgcttca atgagttatt gatttgcatt gcatttggtt taacaactgg
    21181 ttggtttcga taatctaaaa caggaaataa ttcggtttcc gtgtgtcctt taaccgttac
    21241 tgagacagat acataagtcc cagtttcatc cataagaaaa ggtttatatt cctcaacaag
    21301 aaagtcttga tgagttccag aaacaaccct gtagtgtttg tactcattaa tagttaccgt
    21361 tgcctgtgga tcattctttt tcataatctc ccacgcgtga gcccaagata aataatcaaa
    21421 atttcctttt ttcttgagaa ttttatttaa cttacgacta aaaagttttt caaagttcgt
    21481 tgtccctttg atttcactca tcaaattctg cctccatttc agcaatgtat ttcttacctg
    21541 gtccgtaata agagatatca atcaagttat ctctgtcgta ctcttctagc gcatcaatca
    21601 agccatcttc gatgacgtaa atatattcag gtttattcga atgcttcgat agatggataa
    21661 gataaacatg atcccaaata gttacatggt tgcctaaatc atcttgatcc caagctagtt
    21721 cttcattcgt caaaagattt cgtctgattt ttcgaccact tgtttcctca attttcggct
    21781 tgccccaatc aggatcaatc aaatattgat ctagagtgga aagttctttt tccatatgct
    21841 aaaatctcct tatgatgtgt tttctttgtg actctttgct tgccggcgga gtcacttttt
    21901 tatttgttgc catgcttttt gcttgtcaat atgttgttgg cttaggatga ttggtttata
    21961 gtatttccac cagcaattag caattgccgt ccctattctt agcgcttcag ctctattcat
    22021 tgtcatcacc aaaaagtctc tgttgtctgt tcagttgatc aatttccata cggatcgcag
    22081 tttctggcaa ccacatttca ataaatgaaa cagcatcatc gaatctctta cgaggtaact
    22141 cgccatatct tgggattgaa aaggtacgtt taaattcaga ccaaaatttt gagaatactt
    22201 ttttgctgat ttcttcataa gctcggcttt cttttccccc tagaactccc ataactttca
    22261 tatttccttt ttgcttaatt tcaaactctt gttgtccgct aattcgcata gtatctttaa
    22321 gcatggaaac atctttttta acatctttca tttcttctaa ttgatagatc atcatatctt
    22381 caattgtttg aggaacagta ttcttgcgaa taacatcttc catttcgttg aatgcttcaa
    22441 tgtatttttg tttgaagtag atagctttct ttcctgtaaa ccccatagcc agcaagaaaa
    22501 atccatctct actaatgaag aaaactcgtc gatttctgcc atatgaatct ggttcattac
    22561 cttctacaaa catctgtcca aaattggaca catctttttt tagtgcatca atatctctta
    22621 aaacatgttg atgttttttc tcgaagcttt ctgccacttg taagctcgta gtcacagctt
    22681 ctttattttt caaaattact aattcttgca ttatttcttc tctccttttt ggtataattt
    22741 agttaaaaac tggtggtgtt tattttgaat ttttttcact taacaatttt tcaatggatg
    22801 tcaataataa gttttatatt gagtacgttt ttaacaggga taaaaataaa aggaatgcgc
    22861 cctcaactag aagttgaact taatgcttct tacttcgctg cagatatgat ttatacaaaa
    22921 gtaatcattt ctaactattc aacagaacca gctatgttag ttaatttaga actttcatcc
    22981 gctaacttaa accgcagatg gtcagctact ccatttaaga aattaattgc taaaggagga
    23041 tcagtcgatg ataatagaat atactctgaa gctgtaccgc taaatattcc tcctaaaagt
    23101 gctatatctt gttaccttgc atttgaagta gggaaaatta attttaataa actccttaat
    23161 caccaaacaa aaatgatatt tactctaaat agaacccaaa tccacaaaat tgttgatatc
    23221 aaaaatacaa acttcccaat agagaaatta gtgaaagaat taaactgagt aatagtaata
    23281 tacattctag tttctctttt ctattcattt ttagtcagcc ccctcggttg gctttttcgc
    23341 tctgtactca gcttcagctt catcaagccc cataaaaatc caaaccatgt aaacaatcgt
    23401 tcctatcaac gcttgcctgc ttccccaaag tcctaaagcg tagatgatta gcggtgcgct
    23461 gaacactagc gctctattaa attttcccat ccgcttgcct ccttaagatt tccgaaaaat
    23521 ttgtttctaa aaattcaagt gttttacttc ttaaaaatag atatgtgtct cttccttcaa
    23581 ctggataata gacaaatcca tttttgtttt tctcgatatc gataatattt ctatatcttg
    23641 ggttctttaa aactctagaa gtaaaccaat catattttct gttaatccgt tctagcactt
    23701 ctggcaacgt catccatcta ccagtatcat cagctttttt taactcctca taatccactt
    23761 gggagataat tacatagcct tctggaattg ggatttttgc ttctagatat tgcattagct
    23821 gttcctccct ttacaattcg tacatagtga taatcgaatc tataattctg tttgcttctg
    23881 cagaagtctt tttaccgttt aaaattaaag ataagtagct tttgctaatt ccaaatcttt
    23941 cagcaagcat ggtgtaagtt aagaactttg aactttcgac atattctttg attttttctc
    24001 tatctcgttg agtgatttct gcaatgtcag tcatactaaa actcctttct aaccaatttc
    24061 ctctaaatcc atttgagggt aatatccttc tttttttagt aattcgtaga taaatagacg
    24121 ccctttctgt gtccatttgg tattcattac aattttagtg ccaccatcgg ctttcgggat
    24181 ctcagttgta tgagattttg tgtatccttg gttcatgtgt tttttgcaca ataaccattg
    24241 gttaccgact tttttctgaa tacctagttt atgaagtaat ttattcatct gttgtggaga
    24301 catcccataa tctgctgcaa tctgactaat tgttactgaa tctgtagaag ataatatgct
    24361 atctaaatag gagattttag gttcgtactc tgcaatcttt tgttctgcga ttaatcttcc
    24421 agttctttct tcttttagtt gagttgctaa ttgaatgatt gtatctggat taagcaaagc
    24481 ttcttctact ttttctggag ttagataacc tccatgtttt ctaattgctg gcaacacttc
    24541 acttgttacc caacgtttaa attttttggc agagggaagt tttgatttta agattaaact
    24601 gtacaaacca gattcgttga tgattgtcat ctctcttgat tgacctgagg tcgtgattcg
    24661 cgaccccatc ttatcttcca aatctacatg ccgcgacaaa gcatctttag tgtttgaata
    24721 acccaaaaca ctcgcaacgt ctttgcctac aaaatatggt tcatcattta ctaaaattgt
    24781 ccgaacttcg ttttgttcga aattaaaaat ttgcggtgtg ttcatatttc tcattccttt
    24841 cttttatatt cgtaaacaaa tttaacaact tttttctaaa ttcaattgac agtatctgag
    24901 taatactcta tactaagagc ataattaaat aagacataaa aacattgatt ttaaagcttt
    24961 cttggcggtc tgcatttaca
//
LOCUS       DADVXK010000031        24293 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.031, whole genome shotgun sequence.
ACCESSION   DADVXK010000031 DADVXK010000000
VERSION     DADVXK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.031"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            167..853
                     /gene="gpmA"
                     /locus_tag="KB909_001204"
     CDS             167..853
                     /gene="gpmA"
                     /locus_tag="KB909_001204"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6837252.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(1151..1858)
                     /gene="deoD"
                     /locus_tag="KB909_001205"
     CDS             complement(1151..1858)
                     /gene="deoD"
                     /locus_tag="KB909_001205"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6837253.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(1875..2693)
                     /locus_tag="KB909_001206"
     CDS             complement(1875..2693)
                     /locus_tag="KB909_001206"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6837254.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            complement(2717..3883)
                     /gene="deoB"
                     /locus_tag="KB909_001207"
     CDS             complement(2717..3883)
                     /gene="deoB"
                     /locus_tag="KB909_001207"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBB6837255.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            complement(3982..4938)
                     /locus_tag="KB909_001208"
     CDS             complement(3982..4938)
                     /locus_tag="KB909_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837256.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            complement(4938..6071)
                     /locus_tag="KB909_001209"
     CDS             complement(4938..6071)
                     /locus_tag="KB909_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837257.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            complement(6064..7626)
                     /locus_tag="KB909_001210"
     CDS             complement(6064..7626)
                     /locus_tag="KB909_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837258.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            complement(7838..8920)
                     /locus_tag="KB909_001211"
     CDS             complement(7838..8920)
                     /locus_tag="KB909_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6837259.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            complement(8986..9384)
                     /locus_tag="KB909_001212"
     CDS             complement(8986..9384)
                     /locus_tag="KB909_001212"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBB6837260.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            complement(9405..10067)
                     /gene="deoC"
                     /locus_tag="KB909_001213"
     CDS             complement(9405..10067)
                     /gene="deoC"
                     /locus_tag="KB909_001213"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBB6837261.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            complement(10113..11414)
                     /locus_tag="KB909_001214"
     CDS             complement(10113..11414)
                     /locus_tag="KB909_001214"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBB6837262.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            complement(11555..12571)
                     /locus_tag="KB909_001215"
     CDS             complement(11555..12571)
                     /locus_tag="KB909_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6837263.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            complement(12879..13484)
                     /locus_tag="KB909_001216"
     CDS             complement(12879..13484)
                     /locus_tag="KB909_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6837264.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            13680..14603
                     /locus_tag="KB909_001217"
     CDS             13680..14603
                     /locus_tag="KB909_001217"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBB6837265.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            14662..16227
                     /gene="guaA"
                     /locus_tag="KB909_001218"
     CDS             14662..16227
                     /gene="guaA"
                     /locus_tag="KB909_001218"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6837266.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(16718..18349)
                     /locus_tag="KB909_001219"
     CDS             complement(16718..18349)
                     /locus_tag="KB909_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBB6837267.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(18363..20036)
                     /locus_tag="KB909_001220"
     CDS             complement(18363..20036)
                     /locus_tag="KB909_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBB6837268.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(20049..20366)
                     /locus_tag="KB909_001221"
     CDS             complement(20049..20366)
                     /locus_tag="KB909_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6837269.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(20391..21791)
                     /gene="lacG"
                     /locus_tag="KB909_001222"
     CDS             complement(20391..21791)
                     /gene="lacG"
                     /locus_tag="KB909_001222"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBB6837270.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            22028..22813
                     /locus_tag="KB909_001223"
     CDS             22028..22813
                     /locus_tag="KB909_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6837271.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            22816..23508
                     /locus_tag="KB909_001224"
     CDS             22816..23508
                     /locus_tag="KB909_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6837272.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(23782..24153)
                     /locus_tag="KB909_001225"
     CDS             complement(23782..24153)
                     /locus_tag="KB909_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6837273.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
BASE COUNT         7041 a         5409 c         4389 g         7454 t
ORIGIN      
        1 aaaaacgaac agttgcgtgg gcactgttcg tttttttata ttctctactt gttttctcat
       61 agaatcttat ctaatttttc gatggaaatc tcttccaaaa aattgtacaa taaaacagaa
      121 ctgaaaattt cagaaatata aacctatctt aaaaggagag ctaaacatgc caaaattagt
      181 tttttctcgt cacggtctta gtgaatggaa tgcattgaac caatttactg gttgggctga
      241 tgtaaatcta gcaccagaag gaatcgaaga agcaaaagaa ggcggacgca aaatcaaaga
      301 agctggaatc gaatttgatg ttgcttacac ttctgtttta actcgtgcaa tcaaaacatg
      361 taacttgatc ttagaatatt cagatcaact ttgggtacca caaatcaaat catggcgctt
      421 aaacgaacgt cactatggta aattacaagg tttgaacaaa aaagaaacag ctgaaaaata
      481 cggcgacgaa caagtgcaca tctggcgtcg ttcttacgat actcttcctc cattaatgga
      541 agaaactgac gaaggttctg cagcaaatga ccgtcgttac gcaatgttag acaaacgcga
      601 tattcctggt ggagaaaact tgaaagtgac attagaacgc gctttgccat tctggcaaga
      661 tgaaattgct ccagcattac tagacaacaa aactgtttta gtagctgcac atggtaactc
      721 attacgcgcc ctagctaaac atatcgaagg tatctctgac gaagacatca tggatcttga
      781 aattccaaca ggtcaaccac ttgtttatga attaaatgat gacttaacag ttgctaaaaa
      841 atactaccta taaaaaacac tataaaaaag ggactgtgac acgatttgtc acagtccctt
      901 ttttcgtata aacggttttc tcctgccaac ttctcggtca caagtcacaa tattcatcaa
      961 acatgaaaag ctgttttttg aaattgttcc ttgtgactca gagttaaacg gcagattcac
     1021 aacctcttgg taaacggtgt tcaaaagctt acatttgcaa taataagtcc agccaagtca
     1081 aaaacatgag gagctatttt tgcttggatg ttcttattac ttaatgcagg gcagcttttt
     1141 catttccttc ttattctgct atcgctgttt ccaatcctac ttcgatcatt tcattgaacg
     1201 tagattgacg ttctgcagct gttgtttctt caccggtgat caaatggtcg ctaacggtca
     1261 tcaaacttaa tgtctgcaca tggtatttcg cgcctaagta ataaagagcc gctgcttcca
     1321 tttccactcc taaaacgcca agttcagcta attggaacgt ctctgtcaaa tcatctttgt
     1381 agaaagaatc ttccgaaaga acatttccta catgaaccgt atagcccttt tctttagcta
     1441 tctcatatgc tttcagtaat agattgaaat cactgattgg aggaaaatga aaggcttgga
     1501 aatttttttc gatcatcgaa gaactggtcg ctgcaccttg tgctagtact aaatcacgaa
     1561 catggacgtc ttttgacaat gcaccgcatg tacctactcg aatcaatttc tttacaccat
     1621 acgactggat caattcatgg gcatagatgg tggctgatgg cattcccatt cctgttcctt
     1681 gaacagaaat acgttctcct ttatatttgc cggtaaagcc taacataccg cgtacctgat
     1741 tgtaacaaac tggatcttcc aaaaaagtct ccgcaatata tttagctcgc aaaggatctc
     1801 ccggaagtaa aatcttatcg gcgatctcgc cttctttcgc ttcaatatgc acactcattt
     1861 tattgttcct cctattacaa taatgtcaat gtttctttaa ccaatgcttt aaaagattgt
     1921 ttgactctct gagttgtttc tacaacttct tcatggctca gattcgcttg catacctgct
     1981 gctaagttgg taatacaaga gattcctaac acttttaatc cgctgtgagc tgctacgatg
     2041 acttctggaa cagtcgacat ccctactgca tcggctccta ttgtccgaga cattcggatc
     2101 tccgcaggcg tttcataagt tggtccagaa tagcccatat atacgccttc tttaagatcc
     2161 aaacctagtt tttctgctgc tgcttttgct gttgcttgat agtcaggcgt ataagcttga
     2221 ctcatatctg gaaatctagg gcccattgca tcttcattcg gaccgatcaa aggattttca
     2281 ccagtaaaat tgatatgatc ggtaatcagc atcaaatctc ctggtacaaa tgattcgttg
     2341 acaccaccac atgcattagt cacaatgact gaatgggccc ctagtccggc catcacacgt
     2401 actggatagg tcactgtttg catggaatga ccttcatagt agtggaatct cccttgcatg
     2461 gctaacactt tcttgcctgc cagagaccca taaactagct ttcctgcatg cccaactact
     2521 gtcgaaacag gaaagaacgg gatctcatca taagaaatca ttacagcatc ttcgatttca
     2581 tctgctaatt cacctaatcc tgaacctaga atcaaaccaa aatcaatttc ttttactcct
     2641 ttatcaagga taaactgggt cgtttcttgt aacatctcgc ttaacttggt catttgcttt
     2701 ctcctattta aaaagattat tttaataatt tcaagaagct ttcgccattt tcagtcgaag
     2761 aaacactaaa gttctcagca atcgttgctg aaatatctga ataatatcct tgaggcaatg
     2821 ccccttgttc tttcattttt ttactgtaaa ccaataacgg tacatattct cgcgtatgat
     2881 cggtaccagt aaacgtcgga tcgtttccgt gatcggctgt aatcattagc aagtcgtctt
     2941 cttccatcgc ttcaagcaat tctggaattc gtaagtcaaa ttcttcaatc gcatgcgcat
     3001 agccgactac atcccgacga tgaccgtata atgcatcaaa atctactaaa ttggtaaagc
     3061 tgattcctga aaaatcgttt ttcataactt tcagcagctg gtcaacgcca tccatattgc
     3121 ttttcgtgcg gacagattca gtgattcctt gtccgttgaa aatatcgttg atctttccaa
     3181 cagcaatcac gtcctttcct gcttctttca aagaatcaag gactgtgtgt ccgaatggat
     3241 tcaacgcata atcatggcga ttgcttgttc gtgtgaagtc tcctggttca cccacgtacg
     3301 gacgtgcaat gattcggcca atcatatacg gatcatcttt tgttatatca cgaacgaatt
     3361 ggcaaatccg atataattct tctaaaggaa tgatttcttc atgtgccgcg atctgaagga
     3421 caggatcggc agaagtatat acaattaaat cgcctgtttt catttggtgt tcaccgtaat
     3481 cgtcaataac agctgttccg ctataaggtt tgttacatac gactttacgg ccagaaaatt
     3541 cttcgatttg tttgatcaga tcatcaggga atccattagg aaacacacga aatggagttt
     3601 tgatattcaa tcccatgatt tcccagtggc ctgtcatcgt atctttccct acagaaactt
     3661 cttctaattt cgtcgcatag ccttgatgat ctttcactga ttccacacct tcaagaggac
     3721 ggatcgttcc taaaccaagc tgctctaaat gtggaacgtt caatcctgct tctttcgcaa
     3781 tgtgtcctaa tgtatcagaa ccaacatcac cgaacttatc ggcatctggt gcttctccaa
     3841 ttcctactga atccatgacg atcagatgta cgcgtttaaa catgattatt ccttctttct
     3901 ttttattttt attgccttta aaacaaaaag ggcgagacga aaaacacttc ccgtaaccca
     3961 ccctttttat tcgctaaaag attattttga tttgatatag ttcttcccgt ttgcttttgg
     4021 accagaagct ttccctaaga aaacaaccag cacaatgatt gtcagcaaat atggagcaat
     4081 ttgcagcaat actggcggaa tcgaagaaat aactggtaat tgtgcgccaa tgatactcaa
     4141 gctttgagca aaaccaaaga acaatgaggc acccattgcc cctaaaggat tccacttacc
     4201 aaagatcata gcagccatgg agatgaaccc ttgtccaacg atcgtaccag ctgaaaagtt
     4261 accggaaatc gactgagcaa aaacagcacc gcccataccg cctaacaagc cagaaatcag
     4321 tacgcctgaa taacgcatag catatacatt gatacctaat gtgtcggcag cttgaggatt
     4381 ttcaccaact gaacggaggc gcaagccgaa tttcgtcttg aagatgatca cccaagctag
     4441 gacagcaatc aaaatagcac aataagcagg taagaatgta tttttaaaga aaattggtcc
     4501 aatgaccgga atatctgcta atcctgggaa agaaaaatac cccagattct gcgtgatgtt
     4561 atcagtttga cctttaccat accatgcttt gatcaagaaa acacctaaag caggtgccat
     4621 cagattaatt actgtcccgc tgataatatg gtcagcacgc aaactgactg ttgctactgc
     4681 gtgaatcaga gaaaatagga tacctacgac gccacccact aaaatagcga tccatggtgt
     4741 catagaacca agtgatggac tcatcgtcaa gttgaaaacg atggaactaa aagcacccat
     4801 gaccatgatt ccctctagcc ctacgtttac gatcccgctt cgttcagaaa aagttccgcc
     4861 tagtgacgtt agaattagcg gtgttgaata aaccagtgta gaagtaagga tcaaggcaat
     4921 taattcgata gtcgacatta tagttcgccc ccttcatggt tttgattcgt tggtttcgat
     4981 tctattgtcg caacgatctc ttcttgtttt ttcccttgga agactttagc catgacgaaa
     5041 cgaatcagga agttgatccc gacaaagaag ataatcaaag caatcgatac attgacgatc
     5101 tcaaacggaa cacctgctcc tgtctgcatg ccaagtccac cgatcttcaa aatactgaac
     5161 aagatcgctg ataaaagaat accgattgct gatccagaac caagcaagga aacagccatt
     5221 ccgtcaaatc caatagatag cgaagtcgtt tgaacaaaga agttttgata cgttcctaat
     5281 ccttcaacca caccgccaag ccctgccaaa gcgccagaaa tgaccatcga caaaacgatc
     5341 gtacgtttac tactcattcc tgcatactca gaagcaaaag gattcaatcc aacagaacgg
     5401 atttcaaatc ctaaagtcgt tttcttcatc agcagccaaa cgaaaataag cgcgatgatt
     5461 gctaaaaata atcctgagtt tacgcgagag ccgccaaaag cttgtgttaa ccatggtaac
     5521 cgcagtgagg cattttgact gatcatattg gaagagtcca aacttgagcg atagctttca
     5581 ggcatcactt catgtaaagc aaatgtgctt acgtataata agatatagtt catcatgatt
     5641 gttacgatca cttcacttgt tccaaaaaat gctcgaagta aacctggaac agccgctgcc
     5701 atcgcaccag ctaaggcacc taagatcacg cataacggaa gcaaaacaac ttttggcaga
     5761 tctggaaacg caagtgccac ccagacactg acgatccacc cgcaaagtgc ttgtccagaa
     5821 agcccaatat tgaaaaaccc agctgagtta gctacagaaa aacctaatgc tgtaaaaatc
     5881 aacggcgttg cttgccttaa cgtttcacct atccctcttt gcgaaccaag ggctgcatct
     5941 agcatagaag aataaccttg gatgggctga aaaccaaaag cagccatcaa tatcgcgcct
     6001 aagatcaatc ctaaaacaac tgaaagtaca ggcactaata aattacggaa tttttcgctg
     6061 cgatcattca tgtgcgccag cccccttttc taactctttt cgtgcttctt ctaaggtata
     6121 gcccgccatc aatagaccta attcattttc agatgtttct ttcggatcaa cgataccgac
     6181 aatttctcct tcatggataa cagcaatacg atccgaaaca tttaaaattt cttctaattc
     6241 gaaactgatc agtaacactg ctttgtattt gtccctttgt tcgatcagac gtttatgaat
     6301 aaattcgatc gcacctacat ccagtccacg agttggattt gcaacaatca acagatcagg
     6361 atctcggtcg acttcacgag cgataattgc tttttgctga tttccgcctg ataaagcttt
     6421 tgcgggaaca agttcattcg ttgttcgaac atcatattct tcgatcaatt ctctggcatg
     6481 ttcattcatt actgaataat tcagcatgcc gtttttactg taaggttttt gatgataggt
     6541 ttgtagtgcg atattttcag ataatgtcat atctaggact aacccgtatt tatgacggtc
     6601 ttctggcacg tgtcctacac catgttcagt gatttttcgg ggttttttat tagtgatgtc
     6661 ttcccctttt agcttgatat gtccgctttc tgcctttcgc aaaccagtca aagcttggat
     6721 caactccgac tgcccgtttc catcgattcc agcgatacca agtacttcgc cagcacgaac
     6781 ctctaagttc aagtttttca cggcttctaa tccacgattt tctttcacca ctagattttc
     6841 aatagacaaa acgacttctt gaggcttcgc ttcttttttc atcgttttga atgaaaccgt
     6901 tcttccaacc atcatatcgg ctaattgttg tgaggttacg tctttaacgt tgactgtacc
     6961 gattcctttt ccacggcgga taactgtaca gcggtcagct actgctttga tttcatctaa
     7021 cttatgcgta atcaaaatga tcgacttgcc ttctttgact aattccttca tgatcacgat
     7081 taattcatca atttcttgag gggtcaatac agctgtcggc tcatcaaaaa tcagtacatc
     7141 tgctcctcgg taaagtgttt ttaaaatttc tacccgttgt tccattccaa ctgaaatatc
     7201 acgaacgtaa gcatctgggt tgactgacaa tccatactgt tcagaaactt tttggatctc
     7261 ttttcgtgct tttttatggt caagcatccc tgcgcgacta ggctcgcttc ccaacacgat
     7321 gttttctgtt acagtaaagg catcaacaag cataaagtgc tgatggacca tcccaatccc
     7381 taattggttg gctttggtcg gacttgtgat ctttacttct ttcccacgca tcaaaatttt
     7441 ccctgatgtc ggctctaata atccggaaag cacgttcatc aatgtagatt tgccagcacc
     7501 gttttctcca agcaacgcat gaatttctcc tgcctttact tgtaaattga tgttgtcatt
     7561 tgccttgaat gttccaaatt ctttggtaat attctgcatt tctatgacaa tattttcttg
     7621 aaccaccttt ttttcacatc ctaacgattt ctatctaggg caacgattga ctaagattca
     7681 cgcttagtga gcgttcttct tttgaaacaa acattacttc agggagttgt tcccttatcc
     7741 aaactgtcac aaggcagctt ggataaatga acaattcttg ttctaatcaa accatagcct
     7801 tgtcaaacat gtgtctaaca aggctataga aatggtttta gttttcttca ggagtttctg
     7861 gaacttttac gtcacctgaa atgatttttt cttttgcttc atcaactgct tttttcgctt
     7921 cgtcagaaag ttgtccttct gttagaccaa caccgtcttc tttcaatcca taaacagtgt
     7981 gttcgccgcc agggaattta ccgtccgctg atttttgtgc caaatcttct actactgttc
     8041 caactgcttt cagtgtagat gtcaatgtga agtttttctt ttcgccgttt aatgtgtatt
     8101 cgccttcgtc tgattggtcg cggtcaacac cgataaccca aacttttttg tcgcctgatt
     8161 cgttcaatga ttttgcttct tggaatacac cgttacctgt accgcctgaa gcatggaaga
     8221 tgatatctgc gttttgtgca tacatacctt gagcaattga acgtccttta tctggagcag
     8281 agaagtcacc agcatattga ttcaatactt tgatttcttt tcctaattct ttcgcacctg
     8341 catcaacacc ggctttgaat ccagcatcaa aacgatcgat tacttcacct tttacaccgc
     8401 cgataaagcc gactacgttt gtttcagtcg tataagctgc tgcaacacct gcaagataag
     8461 aagcttcgtt gtctttgaaa gttgcagata caacgttatc taatccatcg atgacatcat
     8521 cgataataac aaagttcgta cctgtattgt ttgttgcttg ttcttggatc gctggtttta
     8581 gtttataacc aataccaaaa atcgttttga atccagcatt caatgcttgg tcaatatttg
     8641 ggatgtaatc tgattcattt gaagattgga aatattggaa gccatcattt cctcgtgaaa
     8701 gtccttgatc tttcccccat ttttctagtc cttcccaagc tgactggttg aatgaacggt
     8761 cgtctacacc acctgtgtct gtgatcaatg ctgcagttgt tgtgtctgat gagcttttgc
     8821 caccggatga atcagtagag ccgttgttgc cgcatgcacc taaaaataac cctgctgcta
     8881 gtgcgacagc acctaaacca aataattttg cttttttcat ttctgtaaag cctcctaaaa
     8941 taattgtttt atttttcaac agtcagctga ctgaatgaac atgagttata gatctttttc
     9001 agtaaatgca taaggcagca gtgcacgaac ggtcgttgcc ttcgtcacac cattgtctcc
     9061 tactagcgta accggcatat caggggaaca gaattctgcc attacttgtc gacatgcacc
     9121 acaaggagag ataggatcgg gggtgtgccc cgctacgact agatgcgtaa atgttttttc
     9181 tccttcagat actgctttga aaaaagctgt gcgctcggca caattcgtta atccaaatga
     9241 tgcattctca atgttgatgc cttgataaat cttgcctgat tccgttacga gacaagcgcc
     9301 taccggaaaa tgggaataag gaacataggc tttatctaac gcttcaatag ctgtgttgat
     9361 ccattcttgt ttgagttctg ccatgagctt ctcctttgaa aaaattaata gccttcacca
     9421 gttgaaccag atacgattgc tactcctgcg cttgttccga ttcttgtagc accagcttcg
     9481 atcattgcca ttgcttcttc ttcgttatgg ataccgccgg aagctttgac acccatttct
     9541 ggtcctacag tttcacgcat caaacggaca tcctctacct ttgctccgcc tgttgagaaa
     9601 ccagttgatg ttttgacaaa atcagcgcct gcagcttttg ctatttcgca agctcggatg
     9661 atttcttctc tatctaataa cgatgtttca ataataactt tgacaagcgc acgatctttt
     9721 gctgcttcaa caactgcttc gatatctttt tggacttgtt gatcatcctt tgatttcaaa
     9781 gcaccgatat tgatgaccat atcgacttca tctgcaccgt tattgatggc atctgttgtt
     9841 tcaaatgctt ttgtctcggg tgtgtttgct cctagaggaa acccgattac tgtacatacg
     9901 gctactggct caccttgtaa ttgttctttc gctagcgcaa cccatgctgg attgatgcag
     9961 acagaataaa aatggtattt ttttgcttct tcgataattt gcatcacagc ttctttagat
    10021 gcgtctgctt tcaaaatagt atggtcgatc attcggttta gttccatttc ttttcccctt
    10081 ttctttaaaa cggtaaagtc cgcttttttc ctttattctg tgatgatgtc atgaatcaac
    10141 gttggcttca ttgccgattc accaatttca atatttttat ataataattc aatgacagaa
    10201 gtgatttctt cgtcgttact atagatcgtc aatagtgact caccttttgt cacagtgtca
    10261 ccaatttttt tatgcagttt caatccaaca gcgtgatcaa tatcttcttc tttggtttta
    10321 cgcccagcac ctagcatcat tgcagcaatt cctaattcat ttgccacgat ttttgacaca
    10381 actccgcttt gtttagcagg aagctccatt gtgtagcgtg cagtcaaaat tcgttctgga
    10441 tgttccacga tcgctgggtc tcccccttga ttttggatca tttctttgaa ttttgctaac
    10501 gctttacctg attccagagc ttcttgaagc aacgttcttg cttcatcggt tgtcttagct
    10561 ttgccagcaa gaacaaccat ttggcttcct aaggcgtagc acatttctac tagatcttct
    10621 ggaccatttc cttgtaatgt ttcgattgcc tcgacaactt ctagactatt tccgatagct
    10681 tcgccaagag gttctgacat atctgagata accgccactg tttctcggtt agccagtttc
    10741 ccaatgctcg tcatggtctt tgccagacgt cttgcatctt cgatgttctt catgaaagca
    10801 ccgtctccag tggtcacatc caaaacgatt gcatctgctc ctgccgcgat ttttttactc
    10861 ataatcgaac tggcaatcag cggaagagaa tcaacggtcg ctgtgacgtc acgcaaggca
    10921 tacaattttt tgtccgccgg tgccaagttt cctgattgac caattaccgc tactttactt
    10981 tcattaacaa tgcgtacaaa ttcttcatcc gaaagctcga tctgaaatcc gggaattgct
    11041 tctagcttgt ctagtgtacc acctgtgtaa cctagaccgc gtccagacat tttagccact
    11101 gtcactccga cactagctac taggggggct aaaatcaatg tggtcgtgtc accaacgcca
    11161 cctgtcgaat gcttatctac ctttattcct tcaagagaac tcaaatcgat gacatcacca
    11221 gaattagcaa tcgccaatgt taagttcgtg atttcttcat ttgtcatgtc ttgataaaaa
    11281 attgccatca ataatgcact gacttgataa tctggaatct ttccattcgt atagttcgtg
    11341 acgatgtact cgatttcctc tttcgacagc tcgtttccat ccctcttttt ttcaatcaga
    11401 tccaccattc gcattgcctg atcctccttg tcttcattcg gtattataca ttatttttag
    11461 gaaaggtaaa ccactttagt aaactggttt actaaaaata aaaaaagcac taactagcct
    11521 ttgtaaatgc ttacataagc aatataccgc cgagttagcc ctttgtcaat acttttacgc
    11581 tctcacgaat aattaatttt gtttcgaaca ctttgttcgg aacttttctt tgaggaaatt
    11641 cgatcgtatc gatcaggaaa cgtgcagcat aaaatccaat atcaaaactt ggctgctgca
    11701 ctgtcgtcaa ttgcggaatc atgtattctg acagctttaa tccatcgaat cctatgactg
    11761 agatatcttc tgggattttt ttgcccaatt catcgatcgc ctgatagcat ccgatcgcca
    11821 tggcatcatt cccgcaaaaa atagccgtga tatctttatg tttgagtaat ttttttgatg
    11881 cagtatatcc accttggaca gtcaactctc catgttcaac aaatttccca ttaaaaggca
    11941 ggccatgatc tttcagcgca tgacgatatc cgttgaaacg ttcttctaat tgatagtatc
    12001 cagtggtttc cttcagcatg ccgatcttcg tatggccatt ttcaataaac agcgaaacag
    12061 cttgataggc gccctcatat tcctttacga taagccgtcc gttatcccga cgattcaatc
    12121 cgcgatcgat taaaatgatt ggcatttttt gataaaaacc gctgtctaat gcatatttct
    12181 caggtaaaat atttggtgtg gccagcaaga ttccgtccac tgagcggtgg gaaagctctt
    12241 gtaaatactt gatctcattt tcttggctat gacgagaatt gcataacatg atcacatagc
    12301 ccaaaggatt caaatagctc tctacacctt cgatcagttt ggagaagaag aaatcagtga
    12361 catcagggac gatcattccg atggtctttg aatgtcgatt gatcacattt gaagcgaaat
    12421 aatcgggctt ataatgatgt tcattcacga tcgacaacac tttttttctt gtcttatcac
    12481 taaatctgct tcctttgtta ttcaaaatct gtgagacagt tgttactgat acgcctgcca
    12541 tttctgcgat atctctgatg gtcagcttca tcctattggc tcccttctat ctaaattccc
    12601 tatcagtgta ccaaaacccc caagaaaaga atagagaaaa aaggaaagta tgttttttga
    12661 taaaaacctc ctttatctac cgacttggca gccttctata caagttctgt atcttattta
    12721 ttttatcgta aaaaacaacg actctgttcc tactatttct ttttgaagaa aaaatagttc
    12781 tttgttttta aaaacttctc aacaaaaaaa gaactgatac gtacccgtac atgcacgccc
    12841 agttccactc tttcgtcgct ccactatttt tcagctagtt attctttcac acttttgatg
    12901 atataatatc ctttatcttt tgtgacgatt tctgcattac caaatgtttc ttccattttc
    12961 ttttgcgcac tcggcgctcc ttgtttcttc tggatcacaa ttgtcagtgt accgcccttc
    13021 ttcaaccgag gatatgcgcc tgtcaaaatt tcatgtacaa ctttttttcc agcacggatc
    13081 ggcggattgc ttacgatagc tgcataggtt tcttcatgaa ctgcttcata gatattcgat
    13141 tgatggatat caacatgttc gatttggtta cgctttgcgt ttccttgcgc tagacttacc
    13201 gctcgttcat taatgtcgac catttcaaca aaccgctgtg tcgcaaatgc caaagctaac
    13261 ccaatcggtc catacccgca tcccacatct aagatctttc cttcatcagg taactcttcc
    13321 caatcgaaag catcaatcag gacacgtgaa ccataatcca ctgtttcacg tgaaaataca
    13381 ccagaatctg ttacaaattg aaaggttctg ccttttaact caaaagccca ttgttcaaaa
    13441 tcgtgcgccg tatctgggcg ttcagaatag taatgatttg tcatgtcttc catccttctc
    13501 atttctttca tgacaacagt ctatcctttt atgtatccgt gcgcaagtca agaataagac
    13561 tccgtttctt tctattataa agattataca aaaagatcgg caatctctct taagtggtgg
    13621 ggtttgcgtt tattttgtgt taaaatagtt ccattgatgg gagaacgcag gaggctaata
    13681 tgaatgatcc aatgaactac taccgtgtgg caagagaaga atggcgagaa ttttatcgta
    13741 atgggcaagc acctttgaca caagatgaac tagataatat caaaagtttg aatgaccgca
    13801 tttccatgca ggatgttcga gatatctatg tacctcttgc tcatctgatt tatctttata
    13861 tgaaagaatt tgaatctttg ttcttgagta aaggtttatt tcttcataaa tacgtagaag
    13921 taccgccttt tattatcggg atcgccggaa gtgtagccgt tggaaaaagt acaacagcca
    13981 gactgctgca gacgattttg tctcgtacct tcaaacgaag aaacgttcag ctgatcacga
    14041 ctgacggatt tctttatcca aatcgtatat taaaagagcg tggaatcatg gaccgtaaag
    14101 gatttcctga aagttatgat atggagatgc tgatcgattt cttgaaccgt gtaaaatctg
    14161 gtcaggaaga gataaaagta cctgtttact cacatgatgt gtatgatatc attccagaca
    14221 agtacgaatt gatccagcag cctgatatct tgatcgttga ggggatcaat acgcttcaat
    14281 tacctgcgaa tcagcaaatc tacgtcagcg acttttttga tttttctgtc tatgtcgatg
    14341 ccgatcccgt gctgatcgaa aaatggtatt tggatcgttt tggtgcgtta ctggatacgg
    14401 ctttccaaaa tccagagaat tattattatc gttttgctat cggagatcgt gaagaagcct
    14461 ttaaaatggc aaaagatgta tggaaaaatg tgaatttgaa aaatttacag gaatatatct
    14521 tgcctacacg aggaagagcc gatataattc tccataaaac tgaaaatcat atcatcgatt
    14581 cgattttcat gcgaaaatat tagcatttta aaatagtttg actattttga gataaaattt
    14641 aaagggatag gggtaataaa tttgacaaac gttgccgata tgacgaacgt tgaaaagatt
    14701 atcgtattag actacggtag tcagtataac caattgatca caagacgtat tcgtgatctt
    14761 ggagtctttt ccgaattatt gagccaccgc attactgcag aagaagtaaa agcgatgaat
    14821 ccaaagggaa tcattctttc tggcggacca aacagtgtat atgatgagaa tgcatttggg
    14881 atcgatcctg agatcttcaa tttaggtatt cctgtattag ggatttgcta tggtatgcaa
    14941 ttgatcacgt acaaacttgg cggttccgta gagcctgcta aaaaccgcga atatgggaaa
    15001 gccttgttag aagtaacaag cgatcaagct gtcttgttta aagaaacacc aaaacaacaa
    15061 acagtatgga tgagccatgg tgacttggta actaaagttc ctgaaggctt tgaaacagtc
    15121 ggaacaagca aagattgtcc gattgcttct atccaagaca caacacgtaa tttttatggt
    15181 atccaattcc atgcagaagt acgtcattcc gaatacggaa tcgaattgct gcgccacttt
    15241 gcctttgatg tttgtcactg tgaaggtaac tggacaatgg ataactttat cgatatgcaa
    15301 gtagaaaaaa tccgtgaaca agttggtgac aaaaaagtct tgcttggtct ttcaggtggc
    15361 gttgattcta gtgtcgttgg ggttctttta caaaaagcga tcggtgacca attgacatct
    15421 atctttgttg accacggtct gctacgcaaa ggcgaagcgg aacaagtaat ggaaagtcta
    15481 ggcggaaaat tcggcttgaa catcatcaaa gtcaatgcaa gagatcgctt cttagacaag
    15541 ttgaaaggtg tatctgaccc agaacaaaaa cgtaaaatca ttgggaatga attcgtatat
    15601 gtttttgatg acgaagcaac aaaacttgct ggtgaagaag gcgtctcttt cctagcacaa
    15661 ggaacgttgt atactgacgt tatcgaatct ggtacagaaa cagcacagac gatcaaatct
    15721 caccataatg taggtggact gccagaagat atgcaatttg aattgatcga accattaaac
    15781 acattattca aagacgaagt ccgtgaatta gggactcagt taggcatgcc tgattcaatc
    15841 gtttggcgtc agccattccc tggtcctggt cttggtattc gtgttcttgg cgaaatcact
    15901 gaagacaagc tagaaatcgt acgcgaatct gatgctatct tgcgtgaaga aatcgcagct
    15961 gctggacttg accgtgatat ctggcaatat ttcactgttc ttccagggat ccgctctgtc
    16021 ggtgttatgg gtgacggacg tacttacgac tacacagtcg gtatccgtgc tgtaacttca
    16081 atcgacggaa tgaccgctga ctttgcccgt atcccatggg aagtcttgca aaaaatctct
    16141 gtacgtatcg taaacgaagt agcccacgtc aaccgtatcg tgtatgacat cacttctaaa
    16201 ccaccagcaa cagtggagtg ggaataaaga gccaacataa tatggagggg gaatccctat
    16261 aaatcaacat tcttcaatag ctaaaatgct tgattttcat taaaaataag atggttccct
    16321 accaaaagag actataatat aagttaattt gtttcattct tatcataaaa agaagttctc
    16381 gaaaaacgaa ctgttttccg agaacttttt tctatccatc taagtgctca aatcatattc
    16441 acgacggaat tctaaggtta ccctttctta aacaaacttt atgttatctg cacaactttt
    16501 tgcaattttt tcattgcttc ttacgaaatc gttgaactct ctttagcata atacaaagtg
    16561 tagatgaagt ctggtgcttt actcgttttg gtaaaaatga ctggaaatcg tttctggtta
    16621 tttttggcaa aggcgaggtg caggttcgat tcctgccttc tacgctaacg atgtggctga
    16681 agggaacctc cgatcttgaa tcgaaacgat ccgcagtcta ttgtttcacc aatgaaacaa
    16741 aatcaacgtt cgtccaagca tttcctgaag ccttgctata aaccccaatt tcacaaacac
    16801 ctgttgtaat tggaatgtct ttgattgtaa tttttgtcca ttcacttgtt ttaacaaccg
    16861 cagtatttag ttccgctcca ccataatttt tgatatataa ctgattagta tcaaactctc
    16921 ccccagacat tacataggca ctcaatgtgt aagttccttt gcttatgcca ctaacatttt
    16981 gataagctga tgcctcgtat gcttgatcct gccaaaaagt tagtttgtag tccccaaaaa
    17041 aagtgcccgc ttccgttttg atcgtaccct tagcggttcc ttgttgaaac caggtttgcc
    17101 aattggaagg actggtcgtt ggtccatcgc tttcgaaact tgcattttta actagattta
    17161 tttgcgcccc tgcttgttta aacgcacgca agcttggcaa ggcgtttcca gcaaaatcaa
    17221 acatcgcttg gttgtcccat tcgtttccca tagtggattg aacactgaga taattcatac
    17281 ctgcttgtgt tgcccaactc acatttccgt tgtaccaaag aggttcccaa tagaagaagc
    17341 ccgccccgcg attattcggt actgcctgaa tccgatcggc aagatccagc aaatactctg
    17401 cttgtcctgt cggtgttggt tcatatcccc ccgcagctgc ttcggcttca ccaaaagcat
    17461 ttggcatagt atcggcattc gctgttgtat gcccataagc tgtttcaact acgatcactt
    17521 ctttaccata ccgttggctg atcgcattca tattggtttg aagttcattc attgaaccgt
    17581 gccaatacgg ataatacgac actccaatta aatcaaatga cacacctcga ctcgtgattt
    17641 catcaaacca ccaagtaaat gctcctgtat cgccaccatc agctaagtgg agcattactg
    17701 gagttgtttt aggttgagtg tctcgaacag cttggatacc agacttcaaa aaagcagcca
    17761 atcgatcaaa ttctcccccg ccttctcccc aagacttgcc ataaggccag agcattccgc
    17821 tattcagttc attgccgatc tgaaccatat caggataaac gtccagctgc ttcatttccg
    17881 acagaacgtt ctttgtatag tcgtacaatg ccgtattcat ttcttcaaag gtcagacctt
    17941 gccatgcttt aggaagattc tgtttcccag gatcaaccca aaaatcactg tagtgaaaat
    18001 ccagcagcac cttaagtccc agattttttg ctcgttttgc aaggtcaatc gtcgtttcca
    18061 gatcatttgt ccctgctcca taactttctc cattactatt ataaggatcc tgccacaaac
    18121 gcagtcgaac atagttgaca ccattatttt ttaaaatctc taaggcatct tttgaaatat
    18181 cgtcttcata atattttgca ccagattttt ccatatctga caggatcgaa atatctgctc
    18241 cgcgaataaa ttcgctggca gatgcttcaa cagtttttga aacagccccc aaagccccta
    18301 acacagctgc aaataaaaca gctttacgca accaaattcc cattttcatt atggctcctc
    18361 ctttattgaa attggttcag aataaactga acagcttttt caggatctct cgttaatccg
    18421 atatattctg ctccttttgt cgcaaccagc ttgattccta agcgatcggt gtcttctttg
    18481 atatcatcat agtaagaatt gacttgcggt gctaagacca ccatatcaaa atcctgcagc
    18541 atttcgtaat gagaaccata agcacccgcc attgcactga tcggtgcttt cgattcagat
    18601 gcaccttttt ttaaagcatt agctaacatc ccacttgtcc ctgcgccagc acaaagtacc
    18661 aacacattga tttctttatt tgcatcgctg ataacttgac tcgctgccac aggtacttcc
    18721 tcacgtacat cggcagaagc accttcctcg gttgcgatca cctctgcttt ttgtgcttct
    18781 ttctctacta agacagcatc gtatgctttg caaaatggta gatagatcag gaagtcaacg
    18841 acgattagaa ccgctgctag aacaaaagct aagataccca tgcccgttcc tagaaccaaa
    18901 ccgatcggtg ctggagttgc ccaaggcaaa acgtacataa agctgttcat gcccaataca
    18961 tcgacaaaaa acttgaacag gcaaacgttt acaacaggtg ttaacaaaaa tggaataaaa
    19021 aaataagggt tcaaaatcat gggtgccgca aatagcaatg gttcgttgac agcgaaactt
    19081 actggaataa aggaagcttt cccaactgcc ttcaactgct tagacttagc aaagagtagg
    19141 aagataaaag gaacaaccaa tgttgcccca gttcctccca tagttcctac aaaattccct
    19201 aaacccaccg tcagtacttt agaagcttgt tcaccggaat tgaacaattg cagattggtt
    19261 tccacattgg catagataat tgccgcaatt gccggctcca cgatcgacgg tccatgaaca
    19321 ccgacaaacc aaaacagcgc catcgctccc cagataatag cgattcctaa gtacccgtca
    19381 gctgctgtaa atagcggctg cagcaccgta atgattgctt ctgcaaatga gatttggaag
    19441 atttgtcgaa tgcctaaatc aattaaaacg gccgcaaata ctgaaaaaga gaaaggaaaa
    19501 atatctcgga aggtttgcga aatcgttcca ggaacttctt taggcatttt aatggtaata
    19561 tctttcagca cacaaaactt atataaatta actgttaaaa atgcagcgac aaaggaagcc
    19621 agtagtccct ttgtccccat atattccgtt gaaaatccac cttcaatcgg agagacgctt
    19681 aacaacagga aacttaccac agaggccagc atcacagagg tggtgttgat tactttgttt
    19741 ttcggtaagc gacgattcat cgaatcagcc aagcagcgag cagtggttgc tgaaacgagt
    19801 aaccctacaa cacccatcga ataattatag actttccata gccatgtgga gacagattca
    19861 ggccattggt aaccaaaaat ctcaggaacc gcagcaatca aaatgaaaat gcttgaaaat
    19921 aaaatagctg gcatcgctgt taaaaatccg tcacgaacgg ctcctaaata actattacgt
    19981 gagatttttt caaaaaatgg tttccctttt tcgatttgtt taatgattcc atccatagcg
    20041 ttcttctcct atccttgatt ctgtctgtac agtacaataa agtcttgaat cagatctctc
    20101 agcaataaag tggtcattaa atgatcctgc ccatggataa aaatgaatcc catctccatc
    20161 tctttcccag atgcttcttc cgctaaaatt tttgtttgcg aattatgtgc aagggttaaa
    20221 ttttcgtcgg cttctttcaa cgccgaatca acatgttcaa agtttccttg tcttacttct
    20281 ttcaataatt tcaataatgt actgcgagcg tcgcctgaat atgcaacgat ctcaaaacca
    20341 agcatttgta attcctcttt attcatcttt tcttcctcca ttatcactta ttaaataatc
    20401 gttttggttt cactgaccaa cttgtaccag taagctgatt cttttgggta acgcttctgg
    20461 gtttcaaaat caacataaaa caagccatac cttttgttat acccatttgt ccatgagaaa
    20521 agatccataa gcgaccacaa aaaatacccc ttcacattta ccccggctgt tatcgccttg
    20581 cttaaggatt ccaaatagac tctcaaatag tcgattctcg gctgatccat aataatgcca
    20641 tcttcaaact gatctttata ccccatcccg ttctcagtga tatagatttt gttgtaatgt
    20701 gggtaatcgc ttttaattcg cagcaacaag tcatatagac cttctggata aatcagccag
    20761 tcccaatcag ttcgaggaat tccttcttta taaatacgtt ctccgattcc cttcacttta
    20821 taaacagagg tccctttttc acccgtaccg ttatgatgga ttgcattttc tccatcgtaa
    20881 gctttgacaa aatggcattg gtagtgattg atccctaagt agtcattacg cgtggatgct
    20941 tttttcaatt caacgaaatc ttcttcagga aaatgatagc tggcctgatt tgcttcacat
    21001 atctcatcaa gagcagtcaa ggtttcagtt gaataatagc ctaaataggt agcatctaat
    21061 aagaaacgga tcgacaatgc atcgtctaaa aaggcagcat gcttatcttc cggcgcgtct
    21121 gttgccgcat atttcgtctc taatgagtga actacaccaa tttcacccgg aagttcgttt
    21181 tctttgaaat agttcactac acgggcatga gcaaccatca tattatgaag acaggcgacg
    21241 atctttgtaa aatcatattt gattcctggt gggaaaacac ctaacaaata ttgattggtt
    21301 gcaactggat agatttcatt aaaggtactc cacaccttga cttctttgaa ttcatgaaaa
    21361 caaaaaatgg cataggaaac aaatgcttct attgtttctc gattcaaaaa atctccatgg
    21421 tcaaacaaac gtttaggggt atcaaaatga tgcaacgtca caaacggcgt tacgtttctt
    21481 ttcttacatt cttcgaacac acgatgataa aaagcgattc cttctggatt tggtttccca
    21541 gctccatcag gaaaaatgcg gctccaagca atggataatc ttagaccatt tacaccaaaa
    21601 cgttcacaca attcaatgtc ctttgcatat tgatgataaa aatcacttgc cggatcggga
    21661 ctgaatcgcc cttgttcctc taaaaagtca tcccaagcaa cagcgccttt gccaccttcc
    21721 ttagtggctc cttcaacctg ataggctgct gtggctccgc caaaaataaa atcttctggt
    21781 aatttaagca tgtacatctc tcctcaaatc tataatcagt tttcgctctt tctaactgat
    21841 tgcattgtaa acgcatccaa aacatttgtc aacaaaaaca aacacaaata atcataaaaa
    21901 ccagaaaaca gcaataaaat ctattgtaac aaacataaaa accaccctaa atgtttactt
    21961 ttgttcgaat tagattgact gttgtccgtt tatatgatag attatcctta aattagaggt
    22021 gaagacaatg ttgaaaaaag aaagattgct tactatcgta gaaatggtca ataaaaaagg
    22081 aatccttacc gttaatgaaa tcatcaatca attagatgtt tctgatatga ccgttcgcag
    22141 agatttagat gaattagaaa aatcgggcaa gctgctgcgt gtccatggag gggctcaaag
    22201 tctttcctac actttagatc aagaactttc tcacactgaa aaagccactc tgcagattca
    22261 agaaaaaaaa gaaattgctg ccacagcagc ctccttgatt cacgagggag aaacgatttt
    22321 cttaggacca ggtacaacaa tcgaactatt ggcgacgcat ttactgaaca agaaaattcg
    22381 gatcattaca aataattatc cagtttttga tattcttgct caagcagatg gaccagaaat
    22441 tctactgatt ggcggtgatt tccggaaaaa taccggcgca tttgtcggac cgatcaccaa
    22501 cgacaattta agaagactaa agtttacaaa agcatttatc agttcaaatg gcgttcacaa
    22561 cgaagcgatc tctacttaca gtaccgaaga aggagaagca cagcagatcg ctctaaataa
    22621 ttcccgtaag aaatatctac tcgttgataa taaaaaattc aatcgagatg atttttatgt
    22681 gttttataat ttgcatgatt tcgatctgct cattacggat cgccagatct cgcgggaggt
    22741 tcaagagcac tatgcacaat atgtcgatct gcaaattgct gattcaaccg aaaataccac
    22801 tataggagcg taactatgaa agggattata tttgatttca acggaacaat gtttttggac
    22861 tctcatctgc atgaagctgc ttggctgcat atgatacatg atcatacaaa agatggttta
    22921 tcagacgagg atattttaaa aaatattcat ggtcggacga atacggagat tttgaaacat
    22981 ttcatttcag agcatttgac cgcctctgag atcgccgtat tgtcagaaga aaaagaaagc
    23041 tattatcgta tgctttgctt gcaaaatgaa aacgagcttc agttgacaaa agggcttgaa
    23101 gcgactcttg accagctgac tgaccaacag attccattaa cgattgccac ggctactgtc
    23161 aaagagaatg ttgcttttta ttttgatatt ttcgatttag cccgctggtt tgactgggac
    23221 aagattgtct atgacgacgg ctctttccct gggaaaccgc aaccggatat ttttcttaaa
    23281 gcggcagaca aactgagctt agctccggct gattgtcttg ttatcgaaga tgcttactca
    23341 ggattacttg ctgccaaacg tgcggggatc ggaacaatta ttgcaattga tccattcggt
    23401 aaaaacaaaa cagtatttga acaggcacag ctaaataaag atggaaccat caaagatttt
    23461 actggttttt ggacagagca cctgtctgcc acatccgtta attcttaaac gattcaacta
    23521 actaccaaag aaaagcaact gaaatgcaca cctcctttta taaaaaactg ccagtgaaac
    23581 gacatgaaag atacactgct atatccttag tgaaatatag cagtgtatct ttgacttttt
    23641 cattctttta accatatgac gcgttcatct ctatctataa ttaacattaa aaatagtgtt
    23701 ttcacattat ttctcaaacc aatcttaaaa atcatcagga gtactttttt gatatacttt
    23761 tattaatgct gggcgtaatg gttaaaagat ttccactagt tcctctccac caagctgagt
    23821 tgaaaaatgc ttatctgtaa acaacataga caaagaggaa ataaacgttt ccgtatcttt
    23881 ctctgtccca aggatattaa ttaattttcc tactaggtaa gtatcattaa acttaagatc
    23941 tgccttcaca tcaaaagttt tgataaaagc ttttatcatg cgtacaattt tgtctttatc
    24001 gccataattg atttcaccac tcatatcaat atagtcacta atccctgaag aaataatggc
    24061 aactgcttct tctttcgcct tatcagataa ttcatttaat gactgggatt gattgatgac
    24121 ttcttgagtt ttatctgtta cgtaatctct cattatccta tcggcatact ccgcaaagta
    24181 atcttgaaaa aattcttcta cagggtaacc aacttcgttt tcccaaccag gagaaatttc
    24241 attatcagta cttattaaat ctattaaaaa ccaacccgtt ctctgagtgt tga
//
LOCUS       DADVXK010000032        24249 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.032, whole genome shotgun sequence.
ACCESSION   DADVXK010000032 DADVXK010000000
VERSION     DADVXK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.032"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="KB909_001226"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="KB909_001226"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBB6837274.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="KB909_001227"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="KB909_001227"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBB6837275.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="KB909_001228"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="KB909_001228"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBB6837276.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="KB909_001229"
     CDS             complement(3373..4680)
                     /locus_tag="KB909_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBB6837277.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="KB909_001230"
     CDS             complement(4683..5264)
                     /locus_tag="KB909_001230"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBB6837278.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="KB909_001231"
     CDS             complement(5836..7128)
                     /locus_tag="KB909_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6837279.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="KB909_001232"
     CDS             complement(7125..7748)
                     /locus_tag="KB909_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837280.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="KB909_001233"
     CDS             complement(7751..8587)
                     /locus_tag="KB909_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837281.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="KB909_001234"
     CDS             complement(8604..9491)
                     /locus_tag="KB909_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6837282.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="KB909_001235"
     CDS             complement(9507..10790)
                     /locus_tag="KB909_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6837283.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="KB909_001236"
     CDS             complement(11473..12156)
                     /locus_tag="KB909_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBB6837284.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="KB909_001237"
     CDS             complement(12174..12791)
                     /locus_tag="KB909_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6837285.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="KB909_001238"
     CDS             complement(12801..13625)
                     /locus_tag="KB909_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBB6837286.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="KB909_001239"
     CDS             complement(13618..14178)
                     /locus_tag="KB909_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837287.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="KB909_001240"
     CDS             14352..15308
                     /locus_tag="KB909_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6837288.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="KB909_001241"
     CDS             complement(15613..16569)
                     /locus_tag="KB909_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBB6837289.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="KB909_001242"
     CDS             16673..17275
                     /locus_tag="KB909_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6837290.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="KB909_001243"
     CDS             complement(17363..18862)
                     /locus_tag="KB909_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBB6837291.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="KB909_001244"
     CDS             complement(18878..19402)
                     /locus_tag="KB909_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBB6837292.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="KB909_001245"
     CDS             19700..20449
                     /locus_tag="KB909_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6837293.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="KB909_001246"
     CDS             20440..21225
                     /locus_tag="KB909_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBB6837294.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="KB909_001247"
     CDS             21194..21910
                     /locus_tag="KB909_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6837295.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23046)
                     /locus_tag="KB909_001248"
     CDS             complement(22012..23046)
                     /locus_tag="KB909_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBB6837296.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23050..24108)
                     /locus_tag="KB909_001249"
     CDS             complement(23050..24108)
                     /locus_tag="KB909_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBB6837297.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7185 a         5222 c         4223 g         7619 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aataaaaaaa gcttttattt tgctaatacg tattaacatt
    24181 tttaatttta tctttacatt gttacttatt gaacaatagg aaattaaaga aacttttgaa
    24241 acttatgta
//
LOCUS       DADVXK010000033        23729 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.033, whole genome shotgun sequence.
ACCESSION   DADVXK010000033 DADVXK010000000
VERSION     DADVXK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.033"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(102..677)
                     /locus_tag="KB909_001250"
     CDS             complement(102..677)
                     /locus_tag="KB909_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6837298.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(682..1656)
                     /locus_tag="KB909_001251"
     CDS             complement(682..1656)
                     /locus_tag="KB909_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBB6837299.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1680..1724)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1939..2907
                     /locus_tag="KB909_001252"
     CDS             1939..2907
                     /locus_tag="KB909_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6837300.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            3004..3297
                     /locus_tag="KB909_001253"
     CDS             3004..3297
                     /locus_tag="KB909_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6837301.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3415..3651
                     /gene="secG"
                     /locus_tag="KB909_001254"
     CDS             3415..3651
                     /gene="secG"
                     /locus_tag="KB909_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBB6837302.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3754..4509
                     /locus_tag="KB909_001255"
     CDS             3754..4509
                     /locus_tag="KB909_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6837303.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4512..6869
                     /gene="rnr"
                     /locus_tag="KB909_001256"
     CDS             4512..6869
                     /gene="rnr"
                     /locus_tag="KB909_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBB6837304.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6891..7355
                     /gene="smpB"
                     /locus_tag="KB909_001257"
     CDS             6891..7355
                     /gene="smpB"
                     /locus_tag="KB909_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBB6837305.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7657..8376
                     /gene="atpB"
                     /locus_tag="KB909_001258"
     CDS             7657..8376
                     /gene="atpB"
                     /locus_tag="KB909_001258"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBB6837306.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8429..8644
                     /gene="atpE"
                     /locus_tag="KB909_001259"
     CDS             8429..8644
                     /gene="atpE"
                     /locus_tag="KB909_001259"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBB6837307.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8735..9259
                     /gene="atpF"
                     /locus_tag="KB909_001260"
     CDS             8735..9259
                     /gene="atpF"
                     /locus_tag="KB909_001260"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBB6837308.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9246..9788
                     /locus_tag="KB909_001261"
     CDS             9246..9788
                     /locus_tag="KB909_001261"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBB6837309.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9811..11367
                     /locus_tag="KB909_001262"
     CDS             9811..11367
                     /locus_tag="KB909_001262"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBB6837310.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11381..12283
                     /locus_tag="KB909_001263"
     CDS             11381..12283
                     /locus_tag="KB909_001263"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBB6837311.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12306..13712
                     /gene="atpD"
                     /locus_tag="KB909_001264"
     CDS             12306..13712
                     /gene="atpD"
                     /locus_tag="KB909_001264"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBB6837312.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13726..14148
                     /locus_tag="KB909_001265"
     CDS             13726..14148
                     /locus_tag="KB909_001265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBB6837313.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14617..14847
                     /locus_tag="KB909_001266"
     CDS             14617..14847
                     /locus_tag="KB909_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBB6837314.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14944..16245
                     /gene="murA"
                     /locus_tag="KB909_001267"
     CDS             14944..16245
                     /gene="murA"
                     /locus_tag="KB909_001267"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6837315.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16258..16434
                     /locus_tag="KB909_001268"
     CDS             16258..16434
                     /locus_tag="KB909_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6837316.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16569..16865
                     /gene="yidD"
                     /locus_tag="KB909_001269"
     CDS             16569..16865
                     /gene="yidD"
                     /locus_tag="KB909_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBB6837317.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16929..17396
                     /locus_tag="KB909_001270"
     CDS             16929..17396
                     /locus_tag="KB909_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837318.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17481..18365
                     /locus_tag="KB909_001271"
     CDS             17481..18365
                     /locus_tag="KB909_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6837319.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18479..18715
                     /locus_tag="KB909_001272"
     CDS             18479..18715
                     /locus_tag="KB909_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBB6837320.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18803..18883
                     /locus_tag="KB909_001273"
     tRNA            18803..18883
                     /locus_tag="KB909_001273"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18837..18839,aa:Tyr,seq:gta)
     gene            18890..18961
                     /locus_tag="KB909_001274"
     tRNA            18890..18961
                     /locus_tag="KB909_001274"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18922..18924,aa:Gln,seq:ttg)
     gene            19087..19257
                     /locus_tag="KB909_001275"
     CDS             19087..19257
                     /locus_tag="KB909_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837321.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19477..20184
                     /locus_tag="KB909_001276"
     CDS             19477..20184
                     /locus_tag="KB909_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6837322.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20243..20887)
                     /locus_tag="KB909_001277"
     CDS             complement(20243..20887)
                     /locus_tag="KB909_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBB6837323.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            21014..21301
                     /locus_tag="KB909_001278"
     CDS             21014..21301
                     /locus_tag="KB909_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837324.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21409..21729
                     /locus_tag="KB909_001279"
     CDS             21409..21729
                     /locus_tag="KB909_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837325.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            22047..23123
                     /locus_tag="KB909_001280"
     CDS             22047..23123
                     /locus_tag="KB909_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6837326.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23120..23729
                     /locus_tag="KB909_001281"
                     /pseudo
     CDS             23120..23729
                     /locus_tag="KB909_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7840 a         4142 c         5106 g         6641 t
ORIGIN      
        1 ctgagccaga atgtggttca ttctgactca gatttgattt tgcacaactc atcagtcctt
       61 attgacaaag agccttattt tgctaatcca gctctgttta ttcagcctat ttttcttttt
      121 gaatatatca agcgttgtgg caacatagtg atgactaatg aaacaacgac gatagacaac
      181 aaacgatcaa ggtagtctgt acctgcctgt accaagatca cacttgttgt ctgacttaaa
      241 cctaacccat gtaatagctg aacgatcata ctggatcctg aggaggtgat cccgccaaat
      301 aactgaacgg taatgatcga agaaacgatc gttccaggta ccgacaaaat caaagcgagt
      361 aataacagtt tcaagctgtt tttatctttg ccgagatatc ttggcaaaat caatccagca
      421 agcaagcctg tgagaatttg gattggcgaa taatacagag aaaaaatatc tgtagtcact
      481 ccacttaaaa taccgctgga caatcctgtc agcattccag gtacaggccc aagcaatgca
      541 ccagcaaaaa tcgttccgat agaatcgaga tagattggca aacgaagcca taaagcaatc
      601 gttcctccaa tataattgat cccaatacac aaagccatca ctgtaagtac gcgagttgcc
      661 attttgtttt tattcatttt gttagcccat ctttaacctt tccaaatctt tcataatcgt
      721 ttcttcttgt gcatttaaaa gaacggttaa aaactttcgg aaaaaaagac gagtatctac
      781 ttttgtcata attttactgt tagcaggttt ctgccaaaat tcataacgat caaccaatgt
      841 ttgtccacga cttattcctt gagtttccac agcagtgaag cttttgaaac cttcacagat
      901 ggcctcctcg ataaaataag caacagctaa cggatcattg atgacacatc ctaaaattct
      961 ttcttgtttc cagtggaagt caaaataaaa acgagtgatc gcttttagat actctccctc
     1021 ttcaggattc atttgacagc agtattcgag gatagtcggt gtcaagacga tttctcttgt
     1081 cacatctaac ccaaccattt ctatcgtttg tttgagattc tcgaatacat aagaagctgc
     1141 ttcaggatca caccagtaat tgtattcagc aactggcgaa cagttaccat ggcttttgta
     1201 agttccaccc atcgagacaa aacgttccat atgtttccca atatttgggt tgactttcaa
     1261 agcagaagcg atattggtca aaggacccaa agcaatgact gatgtatttg tcttttcttt
     1321 gaaataatca gccaaaaaat caacggcatg gagaggttct gcctgttttc tcaagatcat
     1381 cgggaaattt gtttccccta aaccatccat accatgagtg tcttgtgcac tgatgaaagg
     1441 ttgcttcaaa ggtttttcca ttccttgata aacaggaatg tctaaacgat cacagcgttc
     1501 caggcatttc agcacattct gcgtacctat atctgcaggg acattcccac aaactacggt
     1561 aatagcaact acttcgatat caggggattt gacagctaat gataaagcta aagtgtcgtc
     1621 gatccctgga tcgcaatcaa taattacttt tcgcattatt tccaatctcc tttctttaga
     1681 gatacttagt tttttattct gggaagtttc cgaaccagtc caagacgagc gtcttgatta
     1741 taatgcacga aattagtata ctggctttta ttgcgaatgt aaatgctctc ttacaagtaa
     1801 atctattgag gagaacttta agtaaatgat acaatgaaaa agaaatggaa tttacgtgtg
     1861 ccgaaaataa agaatcctat ggatcggtac attggataat agatagatta tagtttggca
     1921 gaaagcggcg ggtgtacaat ggttattttt tatttcattc ttattctgat aattataggg
     1981 atcagttacc attttctttc ttatttttat gcaaagaaat tagtaagagc gggagtacag
     2041 agaggatatg actggtatga agacactggt catcgtttga tggaccctgc tgcagtcacg
     2101 tcagtagaaa aaaaacgaca aaaattagaa gaagagtgtg aaagcttttg ggagcaggga
     2161 acacccaaaa caatcaaaag ttatgacggg ttgaaactag ctggtcagat gttcatccat
     2221 ccaaataagc agaataaatg ggtcatttgc gtacatgatt accgaagcac agggaaaaga
     2281 gacatgtctc atataggtaa aagatatgca gagaaaggat tcaacgttct tgtacctgat
     2341 ttacgtgcgc acggagaaag tgaaggagaa atcatcggaa tgggatggct agatcggcta
     2401 gatttaattg cctggatcca actcatctta gatgaacagc cgaatgcgtc cattatttta
     2461 cacggcggat caatgggagc ttctacgatc atgatggcaa gtggtgaaaa acttccatca
     2521 gcggtcaaag gatttatttt agacagcgga tatgtttctg tttatgcaga attccgatat
     2581 atgttaagta aaatcactgt ctttcctaaa aaaatggtca tgagatatgc gaatcattat
     2641 gcccagaaat acgccggtta ctccttaaag caagcatcag ctacgagaca gcttggcagc
     2701 aatcatctgc ctttattagt catccatggt gaaagagatc attttgtccc tacagaagca
     2761 gcgtacacga ttcaaaatgc tacggcaggg gataaagcac tgctgcttgt tccggaagca
     2821 gaacacttgg aagcatcgat gaaagatccg aaaacctatt ggacagtgat tttttcattt
     2881 attgaacaaa gaataacgat gaattaattt tctcttcttt tttgtaagta attcgaggat
     2941 aaataattgt ttatagatca ggagactgct aaaataaggt aggaataaaa aaatatcagt
     3001 tatttgagga gtgcggcata tggaaatcaa agaagaaaaa atcgtcttgc tttattcaat
     3061 gatgaacaac aagagatcgg agaaatgaca tggtcagatg cgggcccaga catcatgatc
     3121 gttgaccata catttgtaga tccagcatat cgtggtcaaa agttagctga aaagctagtg
     3181 tatactggag tagaattagc aagacgagac gggaaaaaga tcattccttt atgcccttat
     3241 gcaaaaaaag agtttgaaaa gaaaccagaa tatcaagacg tcttacgtca gtcataagaa
     3301 taacagctga aagttttgaa ctttcagctg ttattccatt tatatagagt tgtcacggac
     3361 ttttatctat gataaagtta aagagacgat atcttttggg aaggaggctg cgatatgtat
     3421 aatttaattt tgggaatcgt gatcgtttta tcgattgtta tggtcattgc gattatgatg
     3481 cagccaagca agcaaaatag tgcagcgagt gcatttaccg gcggtgcgga tcaactattc
     3541 ggcaaacaaa aagctcgcgg ctttgaagct gtcatgcagc gatcaactgc agttatggga
     3601 gctatctgga tgatcttatt atttgtccta gcatatttat cttcgaagta gttgaataag
     3661 cctctcgcaa aacggcgggc ggcttttttt attgcaaaga gaacgcttaa gaagaagtta
     3721 tgaaagaaac tatggtaaaa tgaggcgaaa gaggtgagac gagtgagaca attaccaaaa
     3781 cccctttatg caaaacatgg aaagcgagcg gttttgctgc ttcacgctta ctcaggaagt
     3841 ccaaacgatg ttcgaatgct cgcacgattt ttggaaaaag cagattatac agtttatgcg
     3901 ccgcttttta aaggacacgg aacaatggag ccatatgata tcttgcaaga aaaagcagaa
     3961 agctggtggg cagacactaa aaaagccatc cattttttac agtctgagca gttttctgat
     4021 attgccgtat taggattatc aatgggcggc atctttgctg tacgagcact agaagaagaa
     4081 tcagtgattg gcggcggttt tttctgttcg cctttgtctc ctgtaaaaac aaacgtgcct
     4141 gaaaactttg aaaaatacgt acgtcaagtg ctgaagacag caggtaaatc agagaaagaa
     4201 atcaatgaaa aagcagttgc ttaccgctcg ttagctgaac aacaattaat ggatatacaa
     4261 gatcaggcag caatcgtaga aagtaggttg tcagatatcc aacagccgat atttttagct
     4321 caagctggga aagatgaaat gatcgaccct aatggcgtat ttgaaactgc acgcaagttg
     4381 agccgtcagc gagtgacact tcaatggtat cctgaaagtg gtcatgtgat tacagttggt
     4441 acagcaagac gcgaattaga aaaagacgtc ttggaatttt tagaaaaatt accttggaat
     4501 gaggaataaa tatgacaaaa gaaacgataa aagagaaaat tctctttttc atggaaagca
     4561 gtcgcaaacg cagtttttct atggaagaaa tcgctgaagg tttagggttc caaaaaagcg
     4621 atgattttaa attactagta caaacgattg ctcaaatgga aagagaacag agtatagttt
     4681 tcaataaaaa aggaaaagtg aaacttcctt taaaaccaat cctgatcgaa ggaacatttc
     4741 gagcaaatga acgaggattt ggatttgtaa cgattgatcc cgaagaagat gacatctata
     4801 tcccaaaaga agcgactggt tttgcaatgg atggagacac cgtagcaatc gatatcatga
     4861 agcgagcaaa tacagatatg gatcgcggag cagaggggaa agtagtcgag attcgagacc
     4921 gggcgactac tcagttagca ggggaattcg ttgcttattc agaagaagaa atacaagaaa
     4981 cagatcttta cggcgttgtt atcccgaaag atagaaagct caaccaattt aaagtatatg
     5041 cagcagcaga gggagttcgt ccagttgacg gaagtattgt gctgatcgaa ctgacccatt
     5101 accctgaaaa agggtatgcg actagtttag aagggataat caagcaagtg attggtcata
     5161 agaatgaccc tggcatggat atcctctcaa ttgtcgtggc taatggtatc cctacgaaat
     5221 ttcctgatga tgtattgtct gaagcagatg aagttccaga tcaaatcagc gaaaaggata
     5281 taactggacg tagagattta agaaatcagc tcattgttac gattgatgga gaagatgcaa
     5341 aagatctaga tgatgcagtt acggttaaaa aattagataa cggtaattat tttcttggag
     5401 tacacattgc agatgtttct tactatgtga cacaaggcag tcaattggac agagaagcat
     5461 atgaaagagg gacaagtgta tatttgactg atcgagtaat tccgatgatc ccgcaacgtt
     5521 tatcgaatgg tatctgttca ctgaatcccc atgttccaag gctgaccatg agttgcgaaa
     5581 tggagattga tccaaatgga caagtagtct ctcatgatat tttcccaagt gtgatccaaa
     5641 caacagaacg gatgacctac acagctgtca atcaaatctt agaagatcaa gacgaagaaa
     5701 cgatgcaacg ctatgctcag ctcgtaccta tgttccaaga aatgggtgaa ttgcaccgaa
     5761 tccttgaaac gatgcgaatc aaacgtggcg cgatttcttt tgaggatcgc gaagcgaaaa
     5821 tccttgttga tgctgaagga cacccaaatg acatccagct aagaagcaga ggaattggtg
     5881 aacgcttgat cgaatctttc atgcttgcgg ccaatgaaac ggtagctgaa cattataata
     5941 aattaaatct gccgtttatt taccgaatcc atgaacagcc aaaagaagaa aaaatgcagc
     6001 gcttctttga ttttgcttca gctttgggca ttctggtccg aggaacgaaa ggaacgatca
     6061 caccaaaaga tttacagcat gtgatcgaag gagtagaaga caaaccagaa gctgcagtta
     6121 tcaatactat gttgctaaga agcatgcaac aagcacgcta ttcagaagac aattttgggc
     6181 attatggctt agcggcagat tactacacac actttacatc tcctattcga cgctatcccg
     6241 atctaatcgt ccatcgtctg atccgttctt acagtgaaga taaaagtgaa agcaatcaaa
     6301 gttcgtgggc tgcggaactt cctgaaattg cagatcatag ttctaagatg gaacgtcgtg
     6361 cagtagaaac agaacgtgaa gtagattcca tgaagaaagc agaattcatg atggacaaag
     6421 tgggagaaga attcgatggg atcatcagct ctgttgtgaa attcggcctg tttatcgaac
     6481 tgccgaatac agtagaggga ttgatccata tcaatgaatt gaaacaggac tacttccatt
     6541 ttgttgaaaa tcatttagct cttgtaggtg aaagaactgg tctgactttt aaaatcggac
     6601 agaaagtgcg agtaaaagta gtcaaagctg atccagatga acgagcagta gattttgaac
     6661 ttgtttccgc agaagaggtt acagcgttgg aacggccaaa aacacgaaat ggaaaatcag
     6721 gaaaacgcga aggaaaacaa gcaggaaaac gcccagaaag aaatggcaag aagaacaaac
     6781 gatatagcga tagtaagcaa acgttcggta agaaaaaagg gaagaagcca ttttacaaag
     6841 gtgttaaaaa gaagaaaaag aaaaaataaa atgagttgga ggaaacagct atgccaaaag
     6901 gcgagggaaa attaattgca caaaacaaga aagctcgcca tgattattcg atcatcgaca
     6961 cgatggaagc agggatggtc ttgcaaggaa ccgagatcaa gtcgatacga aacagccgga
     7021 tcaatctaaa agatggattt attcgcgtcc gcaacggaga agctttcttg cataatgttc
     7081 atatcagtcc ttatgaacaa ggaaatattt ttaatcatga tccgttgcgc acgagaaagt
     7141 tattattaca caaaaaacaa atcatccggc ttgaaaatga attgaaaaat actggaatca
     7201 ctgttgttcc tttaaaagtc tatattcgta acggctatgc caaggtattg attggtctgg
     7261 cgaaagggaa aaaatcttat gataaacggg aagatttgaa acgaaaagat atcgatcgac
     7321 aaattgatcg aacattaaaa aatttctcta gataatttca ttatcctttt tcgcatattc
     7381 ggtgcttttg cttttactta atgataaaat ttgttagcat ttaatctgat aaaacatgat
     7441 tatcataggt tttttcttag atcaggagca ccgtgtataa agaaaaattc gcttcgtttt
     7501 tgactgaaat aaaaaagtgt ctaattttca tgaaaatgtt ttgaattttc tgtttcatgg
     7561 tggtatgata ccgtgtggtt agaaaccgat tggaaaaaac cagatacgca catgaattga
     7621 ttttatgtga atttcgggga aaagaggtga aatggattgg atgaacgctc gctaacgttc
     7681 cacattggac caatttggtt tgatggtaca gtttgtataa tggtgttact gacctgtttg
     7741 attgttttct tcttagctta cttttttaca agaaatctta agttgaaacc aacaggcaaa
     7801 caaaatgcga tagaatgggt cattgatttt agtcgaggaa tcgtaacaga taatctgcct
     7861 agaaaagaat tgagcaattt ccatttgttg gcatttacat tgtttttatt tgtttttgtt
     7921 gcaaacaaca tcggtttagt aacaaaaatc gttttaccta acgaaacaac actttggaaa
     7981 agcccgacag cagacccgtt tgttacttta actttggcat ttataatgat cttacttact
     8041 cacttattcg gggtgaaaaa gttaggcttc aaaggatatt tcgtaaattc gttcttgaaa
     8101 ccctatagtt ttatgtttcc gatgaaactg attgaagaat ttacaaactt attaacactt
     8161 gctttacgtc tttatgggaa tatttatgcg ggggaagttt tgctaacctt gattgcaaaa
     8221 atgatgacaa gcttaggctg gttctcatta ccattagcaa ttccattaga gatggtctgg
     8281 atcgcgttct ccttgtttat tgggagcatc caagcatttg tctttgtcac tttgtcaatg
     8341 gtttatatga gccataagat tgaagtagaa gaataatact cggttaaaaa acaaactact
     8401 atttatctat tttaggagga aaacaattat gaattatatc gcagcagcaa tcgcaatcat
     8461 gggagcagca atcggagccg gttatggtaa cggtcaagtt atctctaaaa caatcgaatc
     8521 aatggctcgc caacctgaaa tgtctggtca attccgtaca acaatgttta tcggggtagc
     8581 tctagttgaa gctgttccta tcttaggggt agttatcgcc ttgattctag tttttgccgt
     8641 ttaattgaat cagtattaag gcagaaacaa catcgtttgt tactgctttt ttacatggaa
     8701 actagaaata ctccaaagaa aggaaggctc gcctatgctg aatcaattgg caattgcaga
     8761 agttggcaat gcgatgttag gtaatatcat cgttgtcagc ggctcatttt tgatactact
     8821 ggctctcttg aagcactttg cttggggacc aatcagcgat attttgaaaa aacgtgaaga
     8881 caagatcgcc aatgatttag attctgcaga acaatctcgc atcaactcag cgaaaatgga
     8941 acaagaacgc gaacaacaat tgttagcctc tcgttctgat gcagctgata tcatcaaaaa
     9001 tgcgaaagaa agtggagaat taagccgcca aaatattttg aaggatgctc aagaagaagc
     9061 agctcgtcta aaaagcaaag cccaagctga tatcactgta gaacgtgatt cagcgctgaa
     9121 ctctgtaaaa gacgacgttg cagaactctc tcttcaaatc gcggaaaaaa tcttgaacaa
     9181 agaattatct ccagaaatgc atgaatcatt aatcaatcaa tacattgaag gtctaggttc
     9241 ttcaaatgaa actagataaa tatacagtag gaagacgtta cgggaaagct ttatttgaac
     9301 tggcgatcga ttcaaatcaa gcagaagaaa tctatcaaga tctcgtaagt ttacgtcaaa
     9361 tctatgaaca agtacctgga ttagggaata tgttaagtga tgttcgtcta gaacctcatg
     9421 aaaaacgaga aatcatggac aagcttgtca gcggttatga tgggatcgtt aaaaactttt
     9481 tagaagttgt ttatgagtat aaccgaatgg atgacctttt gttcatgatc gaagaatatg
     9541 aacgtcgata tgatgaacat caagggttac tattgggaag tgtcacaaca gcagtcccac
     9601 tttcagacga acaacgaata caattagaaa agaatgttgc aaaaacaatg gactatcaat
     9661 cagttgaatt aaaacaaatc gttgattctt ctattattgg tggcgcgatt gttgaagcca
     9721 accatcgagt aatcgacgga agcattcgca cgcaattaga aaaaatgcgt aatcaattaa
     9781 acagatagta caaagaggta ggtgaatcga atggccatca aagcagaaga aattagtgcc
     9841 ttgattaaag aacaaattga aaattatcaa aacgtgcttt cagtcgaaga aatcggtacc
     9901 gtaacttatg taggtgacgg gatcgctcgt gcacatggtt tagaaaacgc gatgagtggt
     9961 gagttgcttg aattttcaaa cggctcatac ggaatggcgc aaaacttaga gtcaaatgat
    10021 gtaggtatca ttatccttgg cgatttcgag tccattcgtg aaggagataa agtaaaacga
    10081 acaggtaaga tcatggaagt tccagttgga gaggccttga tcggtcgggt agtcaatccg
    10141 ctaggtcaac caatcgacgg actaggtgaa atcgttactg acaaagctcg tccagtagaa
    10201 gcgatggcac caggtgttat gcaacgtaaa tctgttaacg aaccaatgca aacagggcta
    10261 aaagcgatcg acgcccttgt gccaatcgga cgcggacaac gtgaattagt catcggtgac
    10321 cgtaaaacag ggaaaacttc tattgcgatc gatacgatca tcaaccaaaa aggtcaagat
    10381 atgatctgta tctatgtagc aatcggacaa aaagattcta cagttcgtac acaagttgaa
    10441 acattgaaaa aatatggcgc aatggattac acaatcgttg tgaatgccgg tgcgtctcaa
    10501 ccagcaccat tgctttatat cgcaccatat gctggtactg caatgggtga agaattcatg
    10561 tacaacggta aacatgtatt gatcattttt gatgatcttt caaaacaagc tgttgcttat
    10621 cgtgaacttt ccttgctact tcgccgtcca ccaggtcgtg aagcttatcc tggggatgtt
    10681 ttctacttgc actcacgttt attagaacgt gcagcaaaat taagtgatga tttaggtggc
    10741 ggttcaatga ctgccttacc atttgttgaa acacaagctg gagatatctc tgcttatatc
    10801 ccaacaaacg ttatttcgat cactgatgga caaatcttct tagaaagcga cttgttctac
    10861 gcaggtactc gtccagcggt tgatgccgga ctatctgtat ctcgtgtagg aggttctgcg
    10921 caaatcaaag caatgaaaaa agttgctggg actttacgcc tagacttagc aagttaccgt
    10981 gaattagaag catttacaca attcggttct gacttggatg cagcaacaca agcaaaacta
    11041 aatcgtggac gccgtacagt agaaatcttg aaacaaaaat tgcatgcacc gctagctgtt
    11101 gaaaaacaag tagtgatttt gtatgctttg acacatggat tcttagatag tatccctgta
    11161 gacagtattt tagacttcga acatgaatta ttcgaatatc tggataccaa tcattcagat
    11221 atctttgaaa caatccgtac aacaaaagat cttccagaag aagaagcgtt gaacagtgcg
    11281 attcaggaat ataaagacat gttcttagct acaaaaggaa gtaattcctc tacagaagat
    11341 aaattgaaat ccattcaaaa tgcatagtga ggtgagatga atgggtgctt cattaaatga
    11401 aatcaagaca cgtatcgctt caacgaaaaa aacgagccaa atcacgcggg caatgcagat
    11461 ggtgtctgct tctaagttga caaaatctga agcttcttca cagaagtttc aggtttatgc
    11521 aacaaaagta agagaaatcg ttacgcattt gactgctact cagttaaatg atattgcctc
    11581 agaaaatcct agaggggata tcaattacaa cagcatgctg ctcagccgtc ctgtgaagaa
    11641 aactggttat atcgtcatca ctgcagatgg cggtttagtc ggtggatata acagctcgat
    11701 attgaaacaa acgatgtcta ttttagaaga agaccaccaa tcacccgatg attacgtgat
    11761 gatcgcaatt ggcggaactg gtgcagactt ctttaaagca cgcggtatca atctagcata
    11821 tgagctgcgc aatctatctg atcagccaag ctttgatgaa gtccgcaaaa ttgtaaatat
    11881 ggcaacaact atgttccaaa acgaagtatt cgatgaatta tacgtatgtt ataaccatca
    11941 tatcaattcg ctaactagtc agtttcgtgt agaaaaaatg ctgccaatct cagacttaga
    12001 tccagaagaa gcaacgactt tcgaacaaga atatattttt gaaccttcaa aagaagaaat
    12061 cttgtctcag ttattgcctc agtatgctga aagtttgatc tacggtgcga tcgttgacgc
    12121 caaaacagca gaacatgctg ctggtatgac agcaatgaaa acagcaactg ataatgctgc
    12181 taatatcatt gatgagctga cggtttctta taaccgtgca agacaagggg ctattaccca
    12241 agaaattacc gaaattgttg ccggagcttc ggcactagaa tagtattgag attggaggaa
    12301 aaaagatgag ttcaggcaag attgttcaag taatcggtcc cgttgtcgac gtggaatttt
    12361 ctttagacca atccttacca gatatcaaca acgcattagt tgtttataaa aatgacgaaa
    12421 ataaatcaaa agttgttctt gaagcagcgt tagaattagg ggacggagtg atccggacca
    12481 ttgcgatgga atcaacagat ggtttacaaa gaggaatgga agtcattgat acaggcaaag
    12541 caatctctgt tcctgtaggt aaagaaacat taggtcgcgt attcaacgta ctaggagata
    12601 cgatcgattt agaaacacct ttcccagaag atgcggaaag aagcgaaatt cataaaaaag
    12661 caccagcctt tgacgaatta agtacaagta cagaaatttt ggaaacaggg atcaaagtta
    12721 tcgatttgct tgccccatat ttaaaaggtg ggaaagtcgg actattcggt ggtgccggtg
    12781 ttggtaaaac cgtactgatc caagaactga tccataatat cgcccaagaa catggtggta
    12841 tttctgtatt taccggtgta ggtgaacgta ctcgtgaagg taatgacttg tattatgaaa
    12901 tgaaagattc aggagttatc gaaaaaacag ccatggtgtt cggacaaatg aacgaaccac
    12961 caggtgcacg tatgcgtgtt gctttgactg gtttgacgat tgcggaatat ttccgtgatg
    13021 tagaaggtca agatgtactg ttgtttatcg acaacatttt ccgtttcact caagctggat
    13081 ctgaagtatc agccttgtta ggacggatgc cttctgcggt tggttatcaa ccaacattgg
    13141 caacagaaat gggtcaattg caagaacgta tcacatctac gaaaaaaggt tcgatcacat
    13201 cgatccaagc aatctatgtg ccagccgatg actacactga cccggcgccg gcaacagcat
    13261 tcgcccattt ggatgcgaca accaacttgg aacgtaaatt aacagaacaa gggatttatc
    13321 cagcggtaga tccattggct tcttcttcaa gtgctttagc acctgaaatc gtgggagaag
    13381 aacattataa agtagcaaca gaagtccaac acgtattgca acgatatcgt gaattacaag
    13441 atatcattgc tatcttaggt atggatgaat tatccgatca agaaaaagtg ttagtttctc
    13501 gtgcccgcag agtccaattc ttcttgtcac aaaactttaa cgtggctgaa caatttactg
    13561 gtcttccagg ttcatatgtc cctgtagaag aaacagtgaa aggattccgc gaaatcttgg
    13621 aaggcaaata cgatgatctt cctgaagaag ctttccgaag tgttggccga atcgaagacg
    13681 tcgtagaaaa agcgaaaaca ctaggctact agaaaggggt gccccatgga tcaatattta
    13741 acagtaaatg tggtaactcc tgccggtttg gtctatgatc accatgcagc tatcgtcgtt
    13801 gcacgtacga cagctggtga gcttgggatt ttgcctaaac atgcaccaat catcgttcca
    13861 ttgacgattg atgaagttcg tgtaaaacga acagattcag atacccacgt cgattggatc
    13921 gctgttaatg gcggaatcat ggaagttcgt gataatgttg tttcaatcgt tgctgatagt
    13981 gcggaacgtg aacgtgatat cgatgtatct cgtgcggaac gtgcaaaaca acgcgcagaa
    14041 cgccaaatcg aagaagcaaa agcaaaacaa gatacgaacg aattgaaacg ggcaactgtt
    14101 gcgttgcacc gagcaatcaa tcgtatcaaa gtatctaagc actcataaaa tgagatgcgg
    14161 atgtttatcc gtgtttaaga acagtaaaaa gaggttatga cagaagtggt cagcttcaag
    14221 acataagaag gaatttacga aaattgcttc tcaaattttt gtgaaatctc agcttatttt
    14281 tcgaagaagc tacttctgga acaccgtata tcagaggttg tgaaatcagc gttttgtcct
    14341 gagtattaga gaaacaaatg gaaaatagtt cctcatattt tgccgttttt tgagctaata
    14401 ccgagggtca gatgattgaa caccgtttat ttggaataag ggactgcgac aagacttttg
    14461 tctcagtccc tttttttgca tatttttagc atttatttcc taaaaaatgt aaggggattc
    14521 ctatattttt aagtatactt gtttttcctt ttatacattt tatggtatta tcattttatt
    14581 agttattata aaacaatcgt tagaaaggac gtcattatgc aagtatacgg aattgatgcg
    14641 gtgcttcgaa tcgtgagtca tttggcgttt atctacttag ccttctggtc tttacgttcg
    14701 ttacgcattg aaactttttt cagaccaatg cataatacgc aaattagaat ggcaatcgta
    14761 cttttttcaa tttttttagg gtacactgca agtaattttt tcttagaggt tatcgcttta
    14821 tgccgaaatc ttttcgttag cctgtaaatt ttaaaaaaag gtactatttt aaaagcaagg
    14881 atgttataat agaaaagatt ttgagtaagt gtatgctcat tggaattttt tggagggaac
    14941 aacatggaag agatcatcgt aagaggtggc aatcaattaa atggaacagt aagaattgaa
    15001 ggagctaaaa atgctgtttt gcctatttta gctgctagtt tgttagcaga agaaggtatt
    15061 acgacattag acaacgttcc gattctttct gatgtcttca ctatgaatca agtgattcgt
    15121 cacttaaacg tagatgtaga ttttgatgaa caaaagaatc aagtaacaat cgacgcttca
    15181 agacaattag aaatcgaagc gccttatgag tatgttagtc aaatgcgtgc ttcaatcgtt
    15241 gtgatgggtc cgctacttgc cagaaatgga catgcaaaag tagctatgcc tggtggatgt
    15301 gcgattggta aacgaccaat cgatttgcat ttaaaaggat ttcaagcttt aggagcaaaa
    15361 attattcaaa aaaacggcta tatcgaagca attgcggatg aattgatcgg taacacgatt
    15421 tatttagatt tccctagtgt aggtgctact caaaatatca tgatggctgc cgtaaaagca
    15481 aaaggaacaa ccatcattga aaacgtagct cgcgaaccag aaatcgttga tttagcaaac
    15541 attttgaata aaatgggcgc tcaagtctat ggagctggta ctgaaacaat gcgtattgaa
    15601 ggcgtggatc atttacatgc agtcaaccac tcaatcgtac aagatcgtat cgaagcaggt
    15661 acctttatgg ttgctgctgc aatgacacaa ggcaatgtgc tgattgcaga tgctatctct
    15721 gaacataacc gcccattgat ttctaaattg atcgaaatgg gtgcagaaat cattgaagaa
    15781 gaaggcggag tccgtgtcat cggaccaaaa catatcttac ctacagatgt aaaaacgatg
    15841 cctcatcctg gtttccctac agatatgcaa gctcaaatga cagctatcca attagttgca
    15901 gaaggtacaa gtgtggtgac tgaaacagtg tttgaaaatc gtttccaaca tttagaagag
    15961 atgcgccgta tgaacgctca tgtcaaaatc gacggaaatg tagcaatcat ggatggaaac
    16021 catgaattgc aaggtgcaga agtatatgca acagacttgc gggcagcagc agcattagtt
    16081 ttagctggct tgaaagcaaa tggaatcaca cgtgtgcgta acttgaatta tctagaccgt
    16141 ggatattata atttccatat caaactacag caattaggtg cagacgtcga acgtgtagac
    16201 atggatcaaa cttctgctga aaaaacagca caaacgattg cttaaggaag tggctgaatg
    16261 agtaaccaac gatatatctt attaactttg ataaagattt tagtggtgat cttattgctt
    16321 atccttcttt ttgtggccgg aacgatgatc ggatatggtg tcatcggtgg cggcaatcca
    16381 tttaaagtat tccagccaag tttgtggatt catattcgag acttttttca ttgataaata
    16441 agaatcacag tggttctagt cgatatgaag tgagccatga agcagaacat gataaaagaa
    16501 aacagaaggg aacgttgacg ttagtcgcga tccctttttt tagtaaaaga aaagaaggaa
    16561 tctaattgat gaagaagata ttgatttatt tagttagagg atatcagcgc tttatttcgc
    16621 ctgcatttcc acctagctgc cgttattacc caacctgttc caattatatg ataaaagcaa
    16681 ttcaaaccca tggtgcgcta aaagggacgg taatggggac tgcacggatc ttacgctgtc
    16741 atccttttgt caaaggcggt atcgattatg taccattgac attccgatta acgcgaaata
    16801 agaaagataa aaaagaacca gattataaaa aggttgtgaa aaatacgggt agcactgagc
    16861 gataaagaaa aagaggaaat ttattgtcaa agtaacaact ccgcaactac ttatatgggg
    16921 gacaaaaaat gatcgaagaa ctaaacaaga aagatttacc atggtccttg ttattagatg
    16981 cagatcctga taaagaaaaa gttcaagtat atgtttccag agggagtggc tggatatgga
    17041 aagaaaaaga aaaaacaata ggtgtactga tctatgtggc aagggaaaaa gaatacgaaa
    17101 tcgtcaatgt agcagtaacc ccaacgtatc aaggaaaggg gattggcgga aaattacttg
    17161 agacagcttt tcagaagctt tcacagctag cttcaaacca aactcggatc attatacgta
    17221 ctggcactac tagtagcgct gcgttacacc tctatcaaaa aatgggctat gtggagattg
    17281 gtcgagtcaa agactatttt atccatcatt actctgagcc catttttgaa aatggagatc
    17341 aattaaggga tcaagtgatt ttagcaattc acttacctaa aaatagcttt aactaataaa
    17401 ctttcaattc gagaaaatgc tttcaaatgc taaatagata cattacaata gctttagcaa
    17461 acaaaaagga gaatattttt atgggaatat tagtttttga ttttggtgga tcggctgtca
    17521 aatatggttg ttgggatggc aaagagatta aaggtaaggg acaatttgca acgcctgaat
    17581 cttgggaaga aatgaaaacg caattatttc aagtttataa aaaaatactc gtttcttttg
    17641 aagtcgaagg aattggaatc agctctcctg gagtagtgaa taatgagaaa caggtgattg
    17701 agggaatcag tgcgattcct tatattcatg gatttaatat tttccgagat ttggaaactc
    17761 tgtttcaact cccagtaacg attgaaaatg acgccaactg tgccggaatg gctgaatttt
    17821 atgaaggtgc tgcccgtgat tatcaagatg ttgcttttgt tgtggcagga actgggattg
    17881 gcggggcgtt gttcacgaaa ggacaaataa ataaaggggc acatctttac ggtggagaat
    17941 ttgggttgat gttcttagat ggcgataaga cattcagtaa acttggtaca gcggtacaga
    18001 tggcttggcg ttattgtgaa cgcaaaggtc tcgataaaaa tgcttatacc ggaaaagatg
    18061 tctttgaatt agcagaaact ggagatgcaa tagcaaaaga agaagttgag agtttttata
    18121 cgtatcttac aaagggatta ttcagtattc aattttcgtt tgatccagaa gtgatcgtat
    18181 taggcggcgg ggtttctgca aaagaagggc tcattgatga gatcaaaagc cgaatgaaga
    18241 agctgacaga acaattcgat ctgcatgatt tcgaaccgca gattttatta tgtgagtaca
    18301 gaaacgatgc taatcttata ggtgcagcag caaactatct cgctgtacgt caaggagaga
    18361 attaagagct ttagagaagg tgcagcttgc ataaaagaag agaatgaaat gaataggaga
    18421 tttttaccta aggaatgttt tatttgctgc agtatgataa aatatctgag aggtgaaaat
    18481 gatgtcaaaa aaaaataaag atattgaagt gcgtatagaa gaagtgaaaa aagatatcaa
    18541 aggtaagaat tatgaagtca ctcagttatt tatagggaaa aaaatgattg gtgagatctt
    18601 agcctatggg ccaaaagaat atgaaatttt ctttggtgaa gaagattttg gaaaagaaaa
    18661 aagtcttgaa aatgcgatag aaacagtgat tcgacactgg aatctgcacg aataaaaaaa
    18721 tatcaaaaaa actttcaata aagggttgca aaaatctgga aaattaggta ttataactaa
    18781 gtcaggttga tacaaacctt tcggaggagt agcgaagtgg ctaaacgcga cggactgtaa
    18841 atccgttcct tagggttcag tggttcgaat ccactctcct ccatttcatt ggggtatagc
    18901 caagcggtaa ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca
    18961 gtataccaca atcgtaagct ctcgttagtt cgagagctct ttttttttgc tttgctacct
    19021 tgttccttga agattctgct gaattaagat agagttaagt taactacaag aattggaggg
    19081 atccacatga aatggaaaga aaaagtagac gaagcagctg aaaagttata tgatttggtc
    19141 aaatcagaaa aatacaatat tgaagtgaat attccgaaaa aaggcggaaa agcggtccag
    19201 gtaaaatcaa aacgcccaac gaatcataca aaaaaatgga tggctaaaaa ccgctaataa
    19261 taacaaaaga tccataagtc ggcattttca tcgattttag ggtcttttgt tattttctag
    19321 gttgaacata tctaaaaaat tgtttctgac aataggagta gggagaacga tgtgtgtcta
    19381 aatcctctgt tgatggatag aaacctttat ctttttcagt tgtgaatcag gtatatacca
    19441 gttataatag aagaaacgaa aggacgggtg tacgttatgt cgaatcaatt acctgtatat
    19501 atacagattc atgaccaatt aaaaaatgaa atcgaacaag gtatatggaa agtcggagac
    19561 cgtcttcctt cagaaagaga attagcagtg aaattcaatg tcagccgtat gacgttgaga
    19621 caagcaattc aaaacttggc agatgaagga atcttagaaa gaaagatcgg ttcgggtacg
    19681 tatgttgcgc gagaaaaagt acaagaaaaa atgtctggtg caacaagttt tacagaaatt
    19741 atggaatcac aaaatcgagt accgtctagt cggacaatct cttatttctt gacttcgcca
    19801 agctcaagtg aaatggaaaa actaaacttg agtaaagatg acacgatctt gcgaatggaa
    19861 cgtattcgtt tcgcagatga tgtccctatt tgttttgaag ttgccagtgt tccacaaaag
    19921 ctgatcgatg gctacagcaa agcagagatt actgaatcgt tgtatcgcac gctagaagaa
    19981 aaaggcggga aaaagatcgg tccagcgaat caaacgatta ctgctgtgtt ggcttctgag
    20041 aaaattgctg actatttaga ggtaaaacga agagatgcag ttcttcgttt gcgccagatt
    20101 tcttattttg aagacggtac gccgtttgag tatgtgcgta cgcaatacgt aggaaatcgt
    20161 tttgagtttt atttggaaaa ataaaaaaca ggtgatccct gattccttat tagaaataaa
    20221 agagaatcag aatcacctgt ttttatatat gatcagttat cagttgctcg tgataagaaa
    20281 cagaaccctc ttcaaattgg acttgtccgt tcagcagctc aatgatggat tctttaaagt
    20341 ggttagcact tttttcatct acagcacaga tgacgctaac ttgatcagta tattggattt
    20401 cttttataaa aaaatgttgg agttcaagat aattctgtaa ttttcctagt tgcggatacg
    20461 tgatcatcac agagatctcc tgttgcaagg taccttctac gattccaatg tcagacaatg
    20521 cttgagagac cgcatgagtg tatgctcgta ttaatccgcc tgtgccgagt ttcgttcctc
    20581 caaaatatcg agtgactact gcagctacat tgatcagttg attttttttg aggacttcca
    20641 acatcggtac gcccgccgtt ccacttggtt ctccatcatc gctgcttcgc tggatttcat
    20701 ttttttctcc aatgatgaag gcgctgcagt tatggttcgc tttccaatgt tcttttttta
    20761 tttcttgaat gaaatttttt gcttggtcct ctgattctat tcgtctaaga gaacagataa
    20821 agcgtgattt tttgatctca atctcacttt gtccattttc ttttattgta cgatagcgct
    20881 cgatcatctt gtcacctctt tttttcattt tctttattca gtataaataa agttctaggt
    20941 tgtttcaaca ctgtaacggt tgcgcaattg ctgtagtatg cgataataaa gacaaaggca
    21001 ggtggatctg gggatgcagg aacgaatgaa aaagtacgat gcaattacgc attatttgaa
    21061 gaacaatggc ggctctcaag taacgttgac ctttacccaa tttgacgaac tgctgtttcc
    21121 cagtaacgga cttcccaaaa cagcaaggga aagtacagat tggtgggcaa atgattataa
    21181 acaccctgaa aaaggtgcct atggctggat aaatgcaggc tatgaagtag ttgtcatcaa
    21241 tttggacaaa gaatatgtcg tgttcaataa attagtgaaa tctagttggc tatttgatta
    21301 aataaaccgc gtttagaaaa cgttgacaaa tttctttctt tttatataat aaagtaacag
    21361 acgcgaagaa aacgtttgcg tagtttgttt taaaaaggag agaaaaatat ggctaaaaaa
    21421 acaatcatgc ttgtatgttc ggctggtatg agcacaagtt tactagtaac aaaaatgcaa
    21481 aaagctgctg aagcaaaagg aatcgactct gatattttcg ctgtgtccgc ttctgacgca
    21541 gataacaatc ttgcaaataa agacgtggat gtgttgttat taggcccaca agttcgcttt
    21601 atgaaagctg attttgagaa acgtctggaa ccaaaaggca ttcctttaga tgtcatcaat
    21661 atggctgatt atggtatgat gaatggcgaa aaagtgttag atcaagcaat cgcgctcata
    21721 ggtgaataaa tagaacagta taactatcga acaagcgatc caaaaaatag atcgcttgtt
    21781 ttttcgtata tttttttagg gcgaataata tgaatcattt ttggggtaga aggcttctga
    21841 cgagagatat taaagcaata gactgtgagg aggtaaattt accaaattat gagaagatcg
    21901 cagcagtgga acgtttgggc aactggattc tttgtcatcg ctgtggaatg aggacgtccg
    21961 tcattgttgg acagcttgca gattacggtt atttttgtac acattgtcta tatttagggt
    22021 gatgcgacac tcaacaagat ttatatttgt ttgatcagcc tgaagcaaaa cctcgagaag
    22081 tcgtcttttt ttggacagga cagcttactg aaaaacaaac ggaaatcgca aagagaatac
    22141 tttgccattc agaaaaaaga catcatctta tttgggctgt aacaggtgca gggaaaacag
    22201 agatgcttta tcctatttta gtggaaactt taaaagctgg aggaagagta gcgatttgta
    22261 caccgcgagt cgatgtttgt aatgaattgt ttttacgcta tcgttatgtt tttccagaag
    22321 aaaaaatcac gttgctccat gggaatacag caacggctta tacctttact tcttttgtta
    22381 tctgtacgat tcatcagcta taccgttttt atcggtcctt tgatttaata gtgatcgatg
    22441 agatcgatgc gtttccttat aacggggatg ctgggctagc tcacgctgtg caaacagcaa
    22501 tcagatcaaa cggccgattc atctacttaa gtgccacgcc tgatgagaag ttactaaagg
    22561 aaatcaagca gacatttgag ctccacaaac ttgccttgcg ctttcatcgg cgcttgcttc
    22621 ctgaacccgt gcttgttttc atgaataatt ggcgacaaaa atgtggaaac aaaaagaaaa
    22681 tcaactcttt ggtgcggatc attcagcaac taatcaaaga aaaccgtatc cttttatttt
    22741 gtccaagtat tacgatgatg catcgtttaa aaatcacact gcaagaagct tttccagaat
    22801 atgagataac agatgtttct tcacaagacg atcaacgggc aaagaaagtt cagaaaatgc
    22861 gagaagcaat atacgagata ctgttaacca caatgatcct agaaagagga gtcacatttg
    22921 aaagaatctc tgtcatcgtt ttaggagcag atcatccagt ttttactaaa tcctctttgg
    22981 tgcaaatcgc aggaagagct gatcgtaaag gtccttatac gaacagtcga gtctattttt
    23041 tctatgaaga aaaaacttca gctattcgaa aagcctgtca ggaaatcaaa gaaatgaacg
    23101 aagaagggaa gcagatgctg tgagatgtag ttgctgcggt aaagacatca ttcaaaattt
    23161 aacattcagc gagatcatcg gagtgtcgaa atctagactt cctcagacat gttcagtttg
    23221 ccgcgcacaa ttccatttat tagaagcaaa aggttgtgca ggttgtcaaa aaccaatcca
    23281 tttgaaatac gaggagacga aaaagaaagc aaatactagt ttcgtttact gcaacgactg
    23341 tcaagaatgg aagaagaaat atcctgcata tgattttcaa caccgcgcct tttttacgta
    23401 cgatgaaaag atgcaggctt ggatcaatcg gtacaagttt atgggagata tccgattagc
    23461 agggactttt gcatataaat ggactcagat aaaaaaaaga ttacccggca tatatttatt
    23521 gtccaatacc tttatctgaa aaaaggtggc tagaaagagg attcaatcaa gtaagcgaga
    23581 tgttgaaagc agcaaaaatt ccttttcaga tgctgctcaa aagagagcaa catctgcttg
    23641 ctcaagcaaa aaacacgcga aaggaaagat tggagatgcc tcagcctttt gagcttgccg
    23701 tacctctttc taagatacaa cataaaaaa
//
LOCUS       DADVXK010000034        23639 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.034, whole genome shotgun sequence.
ACCESSION   DADVXK010000034 DADVXK010000000
VERSION     DADVXK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.034"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..308)
                     /locus_tag="KB909_001282"
     CDS             complement(<1..308)
                     /locus_tag="KB909_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837327.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     S"
     gene            complement(405..857)
                     /locus_tag="KB909_001283"
     CDS             complement(405..857)
                     /locus_tag="KB909_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837328.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(864..1412)
                     /locus_tag="KB909_001284"
     CDS             complement(864..1412)
                     /locus_tag="KB909_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6837329.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(1457..1789)
                     /locus_tag="KB909_001285"
     CDS             complement(1457..1789)
                     /locus_tag="KB909_001285"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837330.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(1803..2060)
                     /locus_tag="KB909_001286"
     CDS             complement(1803..2060)
                     /locus_tag="KB909_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837331.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(2255..2797)
                     /locus_tag="KB909_001287"
     CDS             complement(2255..2797)
                     /locus_tag="KB909_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837332.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            complement(2818..3909)
                     /locus_tag="KB909_001288"
     CDS             complement(2818..3909)
                     /locus_tag="KB909_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6837333.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(3917..6127)
                     /locus_tag="KB909_001289"
     CDS             complement(3917..6127)
                     /locus_tag="KB909_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837334.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(6143..8671)
                     /locus_tag="KB909_001290"
     CDS             complement(6143..8671)
                     /locus_tag="KB909_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6837335.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(8723..9133)
                     /locus_tag="KB909_001291"
     CDS             complement(8723..9133)
                     /locus_tag="KB909_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837336.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(9146..9364)
                     /locus_tag="KB909_001292"
     CDS             complement(9146..9364)
                     /locus_tag="KB909_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837337.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(9361..10353)
                     /locus_tag="KB909_001293"
     CDS             complement(9361..10353)
                     /locus_tag="KB909_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6837338.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(10432..11343)
                     /locus_tag="KB909_001294"
     CDS             complement(10432..11343)
                     /locus_tag="KB909_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6837339.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(11362..11706)
                     /locus_tag="KB909_001295"
     CDS             complement(11362..11706)
                     /locus_tag="KB909_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837340.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(11726..12282)
                     /locus_tag="KB909_001296"
                     /pseudo
     CDS             complement(11726..12282)
                     /locus_tag="KB909_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12363..12863)
                     /locus_tag="KB909_001297"
     CDS             complement(12363..12863)
                     /locus_tag="KB909_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837341.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(12864..13409)
                     /locus_tag="KB909_001298"
     CDS             complement(12864..13409)
                     /locus_tag="KB909_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837342.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(13406..14662)
                     /locus_tag="KB909_001299"
     CDS             complement(13406..14662)
                     /locus_tag="KB909_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6837343.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(15022..15333)
                     /locus_tag="KB909_001300"
     CDS             complement(15022..15333)
                     /locus_tag="KB909_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837344.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(15356..16666)
                     /locus_tag="KB909_001301"
     CDS             complement(15356..16666)
                     /locus_tag="KB909_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBB6837345.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(17280..17732)
                     /locus_tag="KB909_001302"
     CDS             complement(17280..17732)
                     /locus_tag="KB909_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837346.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(17734..18099)
                     /locus_tag="KB909_001303"
     CDS             complement(17734..18099)
                     /locus_tag="KB909_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837347.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(18198..22481)
                     /locus_tag="KB909_001304"
     CDS             complement(18198..22481)
                     /locus_tag="KB909_001304"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBB6837348.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(22628..22867)
                     /locus_tag="KB909_001305"
     CDS             complement(22628..22867)
                     /locus_tag="KB909_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837349.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(22957..23229)
                     /locus_tag="KB909_001306"
     CDS             complement(22957..23229)
                     /locus_tag="KB909_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837350.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(23312..23563)
                     /locus_tag="KB909_001307"
     CDS             complement(23312..23563)
                     /locus_tag="KB909_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837351.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
BASE COUNT         7006 a         5086 c         3452 g         8095 t
ORIGIN      
        1 gaatagtctt ttatctcaaa acgcttaatt tcaggcttag gaatatgaat aatcttttga
       61 gtatattctt tctcttttaa tcttactgaa gaaataccac tgcctatctt ttttacaaat
      121 atttcatttg gtgtacagac taataaaaca atatttgtaa tcaatccttg cactaaagaa
      181 ttaaaaggaa gactatttaa aacagggtgt gcataactat aacatgtgaa gtagttattt
      241 tgaactttaa cttttaaaaa ctttaaaaat aatcttattt gttcttctaa acaatcatct
      301 atactcatat aatcactcca ctaattaatc tccccaaaaa gacacagcat taagagatat
      361 accaacacaa cagtgcaaat aactctacat cttccttcgc aaccttattt caataaacca
      421 taaaaattat tttttaatag aaactgaaaa ttaaaactag aaaaagtagt tttaccgaat
      481 gtaagagcat catcaccatc aatatagaaa tacattcttt tccagttaca tttaattttt
      541 aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa acttggtaat ctctttgtaa
      601 ttaattcttg ttaaagaata attaaacact tcatttttac ttgttatttt ttcattgact
      661 ataactagtt catctggtaa aaaaattaac caacaaacat cgacaaacag taaatgatat
      721 aatccatttc cacctccaag catattcaat actggtgaac atgccttaga aacacgaata
      781 tagttatggt ttaaatagat attttcttta aacattgctt gtttaaaagc catatgctct
      841 tgttctaaac ttttcataaa cttttactct aatgcacagc tagcagcagc tgctgcaatt
      901 cctgctacaa tatttacctt agctaactct ttagctgcag cttttcctaa ttgtttttct
      961 gcaattttta ataataaatc cgcagctttt tcaaaattaa aagcttttaa tgcttcaata
     1021 aaatctccct gcgtacctat agcccaagcc actcctcctc caggaagaga attaatggct
     1081 acacatccag catatcgttt ccaatcaact ttctccattc taggaacaat aatatgttca
     1141 taaaagactc ttgctgctct tccttgttcg ttatcttgac tgattcgttc acgaatagca
     1201 ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa aaccaactgt atcaaaataa
     1261 aaagttaatt catctactaa tttattcttt atttctaaat caactgtatt cactttttct
     1321 gtggcataca cacttgttcc agtactaaca aaagtactta aacctaataa gaaaacacct
     1381 aaaacaccaa atattttaat tattcttttc ataatttctc ctccataaaa aataagttac
     1441 tttttaaata tcttgtttat gaattcattc cccaaaggcc ttttaagatt gatacagcag
     1501 tccgttcact tcttttagac ttgtcataca agtcttttaa atgatcccat atcagactag
     1561 tttgtctatc tagcttcaat ccattaaacg ctaatgaacg gttcattttt tctattactt
     1621 tagataaagc tacagaaatt tttatacctt cacaacgcgc atcttggatt tcaataatag
     1681 tatcatcaat tagtttttga atttcttgcc tatcaacata ttcaatctta gaaagagaat
     1741 cttttaaagc tactaatgat tcaacgattt cttttttctc ttcagacatt ttcttcctcc
     1801 ttctagtgac ccgtaaagcc atgtagagca gagtccattg aaccagtaat tacactatct
     1861 acaacgccat tccaatttac tctacatttt ccatttttca gatttgtcgg tccatacgga
     1921 tagccttttt gacattcaat gttcggatta taccagatag gattatacca ttcagccgca
     1981 gaagcagatt cagtcgatac aaacaatccc acaccaacaa atccaataca catcacacta
     2041 tagccaatta gttttttcat ctcgtatcca tctcctaaaa aatagaatag ttcttatagt
     2101 tattcataag acatattttt tccgtttttg ttttatcctt tctgtcctat aacaactttt
     2161 ttcaagtaaa gaatgacata gtttttctta aaaaaacagt ctgttttttt ctatttcttc
     2221 ggtgtataat aaatatgagt gttcattttt tattttaata cgcactccgt acataataaa
     2281 tcttgatcgc atcaatcttt tgagcttctt gacctacttt caattgaagt aatacaaatt
     2341 gagtaacctt attcattgtt tcttctccaa ataacaaata ttgatccgga ttctctatat
     2401 cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg tacatgcggg tctacatcaa
     2461 tactattgtc tttaatacaa cgatctgtca tatagtccct cacagcttga ttgcgtttat
     2521 aaacatctgt gaaattactc cattttctag caaaatcttt taagaaattt tttgtcattt
     2581 catctatttg catttgttgc gctgtctcgt cttctaatga accaatttga ctgttacttt
     2641 cagtactttg aagagttcca cttgtttctt ttactgcttc gattgtttct tctgtcgttc
     2701 tcaattgtgt tttttgtttt tcagaagaaa accaatgaca accagtaaga cctatcaaac
     2761 ataaccaact aaatactaaa attatccctt ttttcacgtt tctagtcact gcctttctta
     2821 tttcacctta cgaaccagac tacgaatttt tgtttgattg tacgtgcgtt gataccgagc
     2881 cataatccgt ccttgctcgg cattctgttc cacactagag aaatgttgtc cgccatatga
     2941 aacatctgtt ataattccgg tgtgaccata gattccagga gacaatgcac cacctgcttg
     3001 ccaattcacc acatctcctg cttgtaaatc acttggtttt gggttcatga ttacttgcca
     3061 accataggtt gtccagttat aatcttcccc tattaacatc gcaaacatgt gtccagaacc
     3121 cattaactgt gggccaccta attgagatac ataccatgcc gtaccaccat aacattcccc
     3181 attatttacg gatcgtccaa tgatccgatc caaaaccttc gcattgcctt tactttttcc
     3241 tgcaataagc gaagtttttt ttgttggtag gctattccaa tgcttgatcg caaaagtatc
     3301 atattccgtt aagttatagg acgttatgat actcattgct cctcgataat acggactccc
     3361 ttcggtaata cctgctgccg catagcctcc acgacctaga atcaataaac aacttccagg
     3421 atctttattg cccacacatt gattaaagtt gctttggctc gccaccataa agccataata
     3481 gtcataacaa gcttttaagt tcggaaactt catatagaaa ccaccttcag aaccaccaat
     3541 tccacgtgca gaaccttgtg ggtagggaca accaggaaac caggtaatcc caaaaaagtt
     3601 cgtatcgttt cttccagatt gtgactgtcc ataagctgat tcatagccta attgagaaag
     3661 aatcacactc ggtaataact gatactttac agctgcacca actgctgctt gcgcatgttc
     3721 atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc ggtaatcctt cggtatattc
     3781 cccattaaaa gcgacagcta gacctgtagc ttctcctcca tgctcagaaa gttctcctga
     3841 aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa agaagacaac ctagacaccc
     3901 tttcttcatt tcttcctcat cctttcttcg ataatggttt ttggactgtt cgtccttttg
     3961 gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg cagtgtttta ggatcctttt
     4021 ctattttttc cgattgctct gttggcttat ctaaagaaga aaatgcaggt tgtaacgatt
     4081 ttggtgcgga aatcgacggt ttactttcag acgaacgttg ccccggttgt tgcacagaac
     4141 gatttcctga tagagtggct accgacgaat taggaacaga gtattggttc aataactgct
     4201 gcattgctgg ataactccca tttttcgcct gatttttcac ttggcgaatc tgttgtgaaa
     4261 gagaaccagc agctgttaat tgtggcacgg gtacttttcc agaaggcaac ggaatcgatt
     4321 gaccaacaaa agcgatacct ttatttaaca atggttttct ttgattattc ccttgttgct
     4381 tactcaattg tgccaatgat tgtacctgtt gttttggtct tactgaattc atggacgaat
     4441 ttggaatcaa accatttgaa agaccagaat tccactctgt tttcgatttg gtagaagaca
     4501 tttcaggctc taccccatga taacgaacat gacgaccact ataaggcaag gcttgatttg
     4561 aacgcccacc tagttcaaag ggattaacca cttgcctccc ttttaccgat tcttgtggtg
     4621 tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc agaagcgagt ggattcgttg
     4681 ctcgatacac attccctgct aatcctgcac ctttgattgc caaattttgt ccagcagttg
     4741 atagttgacc aggcagttgt ttcatttgag acaaagaatg acttgctatg tttttcgtgt
     4801 tgtttatagt ttgatctgca gctcctaacc ctagtttctt taataaatct ttccgtttta
     4861 caatgagtaa aattgatagg agtgctttga caaacatatt tcctaaaaaa ccaaaaacag
     4921 tattcattgg aattaaatcg tctactatgt tatagatcaa aaatgccacc aaaataatca
     4981 cactgtaaaa agatttttga aacatcaagc ccaaaaagga ctttaaggta ttcatgagca
     5041 tataatcaaa tactggaaca aaagaagcga gtaatgaaaa aggaatcaca agtaataaac
     5101 acaacaccaa catttgaaag ataaaacgaa tcatgccaat cactacaagt ggtaatccaa
     5161 tacttagatt aagcaatggc accatagaac caacgactgc tttataaaca gctttagttg
     5221 gttgaatata gacacgataa gccttctttt tccctctatc ttctcctgca gcagtggtca
     5281 cttttgtctc aatatcagat aattcttcac ttgacgcttc cttggctaga aattcttgtg
     5341 gttcaatctc tgcttgatac aattcttcta aatttgttgt cccataattt aacaatatat
     5401 acggatcaac aacagccgct ttataataaa gttggcgcac tttttgaatg gcttcctttt
     5461 gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc caattcatct agactatttg
     5521 tagcagaaaa aataaagcct tctacctcca cggacaaatc atttaaccct ttggtaaaag
     5581 cttctccttt actaggtacg ttactaccat agccaaacca aaccattgaa aaaatgacaa
     5641 cgaagagaaa tcgaataaac accatttttg cgtaatgttt ccctctaaat atacgaagag
     5701 taaatagata taacacatac aagacgacaa tccccgcacc aataggatcg tatatttttg
     5761 aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa ctcgttcatt gcagctcctt
     5821 catagagctt ctcaatgaca aaatcaaggc cttgccaaat caatttactt aaactaaaga
     5881 acatattcgt catcattttt agaaaatctg tgccatttgc cccaaataac attttgccta
     5941 atgaaaattc actatcagat aaataagaag aaaaggtatc aatatgaaat ttcccaatct
     6001 catagatcga ttgatccacc tgcttttctg ccgcatacac caatccacca acaaaaagca
     6061 gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt cttttcctta tgctttatat
     6121 aagccattgt ttcacctcat ttctattgca tgattaacgt atcctgttct tctacttgag
     6181 agtgacttgt tttttccgtt gtttgtaatg cagcggtcat ttcttcaaac aaactgtgta
     6241 cattgagttt tcctacacgt ccatagggat ctaacatcca acactgtcct ttaatcatgt
     6301 ggctcatttc agctaagttc gcttcattta cttccaaacg taaatgattc aaaatctttt
     6361 ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa attccctttt tctttatctg
     6421 aacctaagtc accaataaat tgtgtatcta acactaattg attcatctgg gaacgcccca
     6481 cacgtgccat tgctgcaata atactacgtc ctgcgttcga attattaaat acccatgctt
     6541 ctgtaaaata aatcgctgtt ttcttactac tatctcgttt tccaaacatt tcacaaaaac
     6601 gacctaaact aatcatcaaa cacaaagact ttcgatccgc atctgtatat agttctggtc
     6661 ggacattgtc atttggtaat ttcaaatctt ggatctctaa aatcgttgtt ttggcattaa
     6721 agtctaatcc cgggttttct ccataagaaa atcctaaacg taaaatcgaa tcttctaccg
     6781 tcaagcgtaa aaactcacca tattctcgaa cctctttttg ttccatttgt tctaaatagt
     6841 cgaccacatg catcaagcca acttgttgtc cggcttcttt ttgaactaaa acttcttgga
     6901 ttccctttaa taccgcccct tttaaaaggt gattggtacc taacggactt aactcatcaa
     6961 tcatatcctg ggctacttgt ttcgcatcta ctcgggataa acaaacaatt ggatctaata
     7021 caccataatt acggggattt gtagcatcta acgtgacata actcattttt tgcaaatgtt
     7081 ctacaaacaa agggtaatgt ttctgataat acgggtcttg aatgagtttc gtaaaccatt
     7141 tgcgcttttc tcctttggga tccacaaata aactttgtac attcataaac gaactataca
     7201 aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt ttttccagtt actgctacat
     7261 gaggcgcatc aaacaacgca cctttgattc cttccgcaat ggctagaaga ttcaaaaaga
     7321 caaaacgatt tgacgcataa attaattctt ctaatggtgt tttttctcct cgagaaccac
     7381 catcccctaa tgtatcttgc cgaccaatat accagccgga ttccatacct aattctgata
     7441 ctgctgaaaa caaccattcg ccaactgctt ctacagttgt tcggtgcttc caatgtaact
     7501 gccgtcccaa tggttgccct aataaacatt tatagaacaa ttctcgttga tcattttttg
     7561 cacggtggat atggataatc gtatgaagtt gttgaataac cgttgcacta ttttgacgaa
     7621 cttcttcaac cgtttgaccg tatacaataa aacatgcgat ccaatcgacg acaggttgcc
     7681 cattatctac tcgttgcttt aaatgtttta ctaatcctcg aacagttaat aagcgttcac
     7741 taggttcttc atcattttga accaattcct tatgctctgt tttgaaccgt tccgatagcc
     7801 aattcagttt taaaccaata cctccctgtc ctttcaagcg tggatagtga attttcattc
     7861 gcaattctgc tgggaaagaa agatcctgag caaattgaaa tagatcacaa tttctcatat
     7921 tttcaggtgt ttccccaata ggcaacaatg ctaaataact actccctaac tcatcttcta
     7981 attgaagaag gcctttatgt tccttcggta tacgtacata cgttccttga ttgtctttca
     8041 gtacttccca attattttgt tcttctactt tgtgagccat tcctcgaata tattgcagac
     8101 gattgagata caacagctct ttttttacta agggacgaat agaaaagcta taaagtaatt
     8161 gtgtcacttc ttttacataa ggatcacttt cagaaaacaa agtttccaaa tcatctactt
     8221 ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa ccagattaga tttattacat
     8281 catgaaaact ctccaccgtt gctttttctt tgactttgat tcctaaaata aatgaaggac
     8341 gatagacttg accttctcgt tccaacaatg tcactgtttc ttttgcataa tacgcaccaa
     8401 ttgcttgact atcgggagaa aatccctttc ctaatgtgtc aaacttcgtc cgtaaattca
     8461 ttgttcgtgg atacatcacc aactccacat cttcataatc tgctaaaagc aacagtaaac
     8521 gagccatcat ttcttttatt tcctgtgtct tttttggtgt gttttttgaa attgttcgtg
     8581 gaaaaacatg atagtaggcc cagatacaat cctctccatt taacaaacaa tttttcttga
     8641 atgcttttac tggttctttt acaagcacca atgaatttca cctcccaata aaaaaggaac
     8701 aaccagttga ttgtcccttt ttctaatcct ctaaataaac atacttattc acaaaaagta
     8761 attcttccaa tgcattgttt gataccttgt cccagttata atacacacaa tcaccattca
     8821 tcatacgaat catataacaa aaccaatccc ataaataaaa atgcactttt tttccatcag
     8881 gttttagttt tgccagtgct aacacacata aataggggag tcctatataa aaaacaactc
     8941 ctgctggtgg aaaaaaagaa atgacccaac caataaatga acgtaaaaat aaatattcaa
     9001 agattacgac caacaaaaaa gttgctgcat tgactaatgc aactggaaat ggaagacgcc
     9061 aattgcttgt aatctgttgt acgcgataag gttccgcata aacaatcgaa taatcataag
     9121 gttcccaatc cacttcacta tcctcctaat ccataaataa tttttcaatg attttaccaa
     9181 acgcatcaaa tacacgtgtt ggatcattta agaagaaata aactgcggca cctgctgcga
     9241 tagatattaa tgcatttcct acttttgatt tcataaaatt tcgcaatccc agataaacaa
     9301 ccaccattat taaaaaatag ccaccttgcg ttaatataaa atctacaatt cccttcagtg
     9361 tcatttccgt tcttctcctt tcctatccaa ccaattatgt gttaattttt caacataata
     9421 ctgatttgtt tttttcgtaa tgacaatcgt catttgttct ttttgtaaaa gtgacgtatc
     9481 accatctcga aagacgaccg ttgcttttac aataaaaggt tttttcgttt ctttataacg
     9541 caatactttc atctctactt gatcaacttt agctgtttga ttgagtcctt caggttcttt
     9601 catcatgtat gacatatctt ttgcattgtt tttcgcatac ttatctaaga aatcttccac
     9661 aaatccttca acatctttcg cttccgacgc atcaaccgtt tcgtataatg tgtcatcata
     9721 agtaatcatt cgttgttttt ctgtattctt tggtagtgcc gtaaaataag gataagcaat
     9781 aatacgacag cccttgtttg aaatagaaaa gggaagattg agtacttgtg tgattgtcac
     9841 acttgtttct ttcttactct ctggattcat cgagcgaata tcataagtta ctttataact
     9901 agcagttgga atggtttcaa tttcttttaa tccaataaac gaagcagcag ttaattttcg
     9961 aacacctgaa acacttcctg gttcttgaat aaagttttgt gcataaaact ctttttttaa
    10021 tgtttcttga cgttgttgtt cttgttcatg attatcgaat gtattcatat acaaagcaac
    10081 aaaacgattc ataaaggatt caatttcagg tgtgtacgtt aattctgacc gactttgtac
    10141 ttctttcttt tgtaattgtt ggatttcatc tttcaaaaac gacacttgaa ccttcgtttt
    10201 catggattga aaaaatgcca agccccctga aaaacaaaga aataaaacca aacaccaaat
    10261 ccatttcact gctttttttg aatggatttt cttttgcttc ggtactttct ctgtataaac
    10321 tttttctttc cgccgtagtt gtcgtttttt cataagctac tccttctagt atgtttttac
    10381 tagtacgtac gattgacaac gataagcttg tttttctgaa aaatagtcca ttcaattacc
    10441 ctcattttct attccttttc tctttctttt atatccaaca aatccagcaa tacttgtcaa
    10501 cactcctcct agaacagaaa gtgcaacatg tatttcttca ccagtctttg gtaagacttt
    10561 tgtttttcca tctgctgttt tgatttcaat attgccactt ggaagtttct ttacaggaat
    10621 cgacaaatcc tttaccaaat tcccttcact atcttggatt aatggaatac catcttttac
    10681 accaacaatt gtttgatcac ctgctacttt taatggggtg gttggtgttg gaatatgggt
    10741 caattcctct acattactag tgacaatcgg tacactcatt ccttgagaag tattcgtcgt
    10801 aatttcaccg cttggggtta ccgatactgt gacttctttt gctggaacaa taggtttatt
    10861 ttcttttgga attgcttctg atttttcaac aggttgtttc ggttcttctt tttgttcttc
    10921 actggtagac gacatcgttg gctgttccgt acttgacgaa tcagtattct tttcagaaga
    10981 actggttgtt cctgattgtt ccggagttgt gactatactt gaatccgttg ttgttgaact
    11041 atgcacacct tcttcttcga tcgaatcagt cggtaaagtt gattcaggaa actctggttc
    11101 tggtgtcact ggctcttttt caggtttctc tgactgcaat tgttcaggtt ctgctggttt
    11161 ttccgttgtt cctccattta gctctgtctc aacatctggt aatccttccc ctggcaatgt
    11221 ttctacaatt tctgacttag gtgtttctac agtttcatct gcataaacca atgaactccc
    11281 taattgaaac gaaaataatg aaattcctag tgttgttacg actgctaatg ttgttttttt
    11341 catgattatt cctccaattt tttatgcaat tcgtgttttg ttcatagacg ccgcactaat
    11401 attatctgaa cgataaaaga actcccgtcc gttttcttct aacccaacat atggattatt
    11461 tttgaataat tgaatcaata gttcactggt gttgtatttt ggatagtttg caaaaaaata
    11521 atactgtgct tgtcgcccat ccgaaaattc aacaagtaat tcataacgat accgcttcaa
    11581 tccttttcgt tgttttaaag gatctctata ccaacttgtc catcgttcca ttcgtggata
    11641 gagatagaca cgatacacat agaacaatgc cataccacat accaccaaaa ataataatcg
    11701 ccacataaaa attccccctt ttcttctacc tttcttgaat catcgaacat tcataccctc
    11761 tatagagatt tgaaaaatcc atcatcaatt gttcatataa acgttgttgc aaatagcgat
    11821 tgtttcgaat acataattct tcatagccat caatcacttg atcttctttt tcatagcatc
    11881 ttgtagctct atgacgctca gcttgcaaga cataaccaaa ctctgcacca tatcgttcta
    11941 ctgttaataa ctgttgacta cgcaataatg caatataaca atcacaaaaa tgttcaaccg
    12001 acatttgatt tttctcacgt ttgtgaaata ggtattcttt agaaagcaca ttattcgtta
    12061 aacaatctga taaatagcga taatctggcg gtcggttatt ttcatctgtg aatttttccc
    12121 ataataaact gatttttatt cgttcagcgg ctagatagtc ttgttcgcgt ggataaaatt
    12181 catcaatcgc acaaagtttt ttatcacctg aataaacaaa tccatataat gcgaaacgaa
    12241 ctcttccttt tcaattggct ctcctaaaaa ttccagtgac ataccatctt ctccttccta
    12301 aaaaaaataa aaaagcagaa accgatttgg cttctacttt tctttccttt tatagctctt
    12361 ttttacggaa gaatccgcaa atgacatttt ttcaaaaaat caatcggcac aagttcacga
    12421 aaacttggag caattttgga tagaatcact tccccatctt gtaaaataca atcataaaaa
    12481 tcatcagtta cttgatactt acgcttctta caataattga taaaatagta gcgatcattt
    12541 tctatttcca ttcgttgttc tactaagcgc atacgaacat catcatagaa ataagccaca
    12601 aatcgccctt caagttcatg tttttcaatg ggatactctt ctggtaacaa tctatttttt
    12661 cgtcgtttat acattgctgg ataccttaga agaagttcat ctaaacgtct gtcagtatat
    12721 ggtaactgac gaatcaacga ttctaatcgt tctttataca gatagaataa ttggcgcaag
    12781 caatagtgta ccgcctctgg attttctaat actgttggat cacgtgacca atacgcacca
    12841 acataaatca taattttttt catttagaca atcacaccag caatactaat gaccgatcca
    12901 caataggtag aacaagtggc atagcgacca atttcctcta attctatctc aatctcttct
    12961 aaagaaagat atgtctgttc ttctgttggc tggcgactca tttcccaagt gacagtcacc
    13021 aatgaaattt cttccataag aggtttttcg ctgctaagtg ctgccacaca gttttcatat
    13081 atcttcattt tatcgcagcc ttttttaacc gctaaaatcg caggtattgg caatgaaaat
    13141 cgataaaagc gaatgaattc tagccttcct ttccttcggc taaattccaa ctcttcgagt
    13201 tcttgttcgt atcccttacg aacttctaat aagcgtgcaa tttcttgcca gttctctttt
    13261 tcctgataac gtccagcttt taccgcttgt tcaatataag gaactcgaaa acgaaaataa
    13321 gacaaatcaa ccatcttttc atttaatgct tcgattgcag cctttaaatc caacaggcgc
    13381 agccattctg ttgtcgtata tgcattcatg caattttccc tcctgacgtt cccatccatt
    13441 ctagatagtt ttgttgctcg tcatttagtt cggcattatc aatcccttct tgtacaaagt
    13501 ctcttcctaa aatacgatct gcttcttgta acaactttaa tgtcggagct acttgtttca
    13561 aaaaccagcg ttctgaacga tctaatgaga atttttctgg ctttactgta aaatccaatt
    13621 cttccatcga acgaaataat tttgcccatc gtttatcaac aatccgtgca tcactttcca
    13681 gtctatccca aacaataagt tttgcattaa ttaaaccaac gccaatctct cctaaacgtt
    13741 tcggtgaatc acctaaaata aatgcttcta ctgcttgtgt tgctttctca ttggctaacc
    13801 gtaactcata tcgattataa ataccatatt tcgttaatgc ttctaattct gaaatttttt
    13861 ctcggttcgc aatttcaaaa cgtttctcat aaaaattaaa aaagagagga ctctttcgcg
    13921 atccaaaata caaagataat ccttcacttc gaaaatagcc atcatctaaa aaacaaccgc
    13981 caatattctg gaatctctta aagtccattt ctaataaacc tgctttttgt ttttctagta
    14041 attcaaagag atcgaaatgt tcttccgttt ccaatcccca aagttcatct aacgcaatat
    14101 cgaatcggct acattgcaca cgtgtataac cagcttccaa ctttccttga tttttccaaa
    14161 tggaatatag ccatgttcgc caatctgttt gttgttcacg catgacttcc tcatattccc
    14221 ggcaaccttg tcctgaaaat tgcacaagta cattttctgt tacagttcgt tttgaatgcc
    14281 agaacaccca gatattccca cgaacagaaa gacagtcaaa aagatacaag cccgttggac
    14341 gtgtttcaaa ttctgtcaga tccattcgta atacacgttg aatcactgtt ttgtagtctg
    14401 tcccaaaaaa ggaaagacgc aaataatcaa tcattgctcg aagatctatt ccgcttttca
    14461 tatacaatcg aaagcgttcc ttgattcgtt gttcaaaatc ctctgggatt tttcttttcc
    14521 cttgttccat ctttctaatg taatcttttg agcagcccat caattgcgca aatcttgctt
    14581 gtgatagcgg ctttttatct ccacttatat tatgaattgc acttaacttc tttctgtagc
    14641 tttttagctc aatcggtgtc attttctcgc tccttttata aaataacaaa atcgattttt
    14701 ttaacccttt agaaacaccg atatatcaac tagtccccct cgttttttgg gaaaagtagt
    14761 acaactgctg accttagata atcacttgat acaaaagggt ttataaaact tttttctatg
    14821 tgttatgtta tttctgcccc ccatattata tatcgggggg ctttacacaa agaggccgtg
    14881 cgcaagcgca cgacctcttt gtgagctgca cacgctgcta gcgagtgcgc attataggcc
    14941 catgcttcgc agccttaatg cgcaccgcca ggcagagtgc ggctaccaga ctacgtctag
    15001 agccctcccg atagataata actacaaaat taaatgatct aattttgtta tttcactata
    15061 tttttcagga gaaaaaacgc gataaattga caaagttaaa tcctcttcta aatctactcg
    15121 ataatgatac aatcgagtca atcgttctat atcttttttc gttagcaata cttgattaat
    15181 aacttttcct gtaaaaacac gttctttgcg caaaaagcgg taatcagtta cttgttcaat
    15241 acgattcaac caatcataaa acgttctgga agaaagagaa ggattaatca ttcgtattgc
    15301 tgtagctact ctataataac aactctctgc catttaactt cacctcctta gttgattaca
    15361 aaatatgcgc atcagaaaaa cttgttcctt ttggatcttt tgctaaatac atttggcgct
    15421 ctagttgttc ttgtaacaac tgattatcat ctcccatcgt ttgatcttga ctatcctctt
    15481 ttactgtaaa atcatagaca atcatttcag taaatttctc aaattctttg ataaagtgat
    15541 aatctttgta aacaaatggc gcaaaaaact ctacaggtac atcaaatcct ggaaaagcat
    15601 atccacgacc aggttgatct ttgttgtaaa atggcttatt tttaaaatct tctccaaaag
    15661 tcattaaata accaatggga gacaatcgac caacagaaat acggaatgtt aaattatccc
    15721 gaacaccact tggaaaatat tctgcatctg gtcgttgcat tgctaaaata atgtacatcc
    15781 ctgcttgacg accctttaat actaatggct gaatcaattt atcgactcta tttctcgctt
    15841 ccatatccaa cgaaccataa aaagctgccc attcatcaaa aaagataaaa tgcggtggta
    15901 acccataata agcataattt ttccctggtt catatttagg atctttcatg gttttcatat
    15961 aggcataccg ttgattcatt tcttttaatg catttcgtaa acaaataatc atttcttcat
    16021 ttattttgta aaacacatgt cctttgaata catcgacgtc acctaatgct gctaaatctg
    16081 ccgcttttcc atcgcaaata tctactgtcc caacacttaa acaagcttga attaaagaat
    16141 acaataaata ggttttccca ccaccgattg caccagcaat caacatattt ggtgattgat
    16201 catataccca atccaaagtt ttcattaaat gaatacgtcc attttctgct atacattgat
    16261 caataggaat ccgaccagaa tctgaaagga atacataatt gattcgggct ttttctcgtt
    16321 cttcacgaat taaatcacgc aaaaatactt cagataacaa atgacccatt tttaaaaatc
    16381 gttcgtgaaa acgcccacca tctaaaggaa aagaaaccac taattcttgt ttcttttgat
    16441 aaaaataaac ttttggtaat ctcatttttt cccttgtttg tttctcacta acttgtttct
    16501 ttgtataaac aaaccgattg tcaattaaca ttcgaacaag taactgacgc caataaacag
    16561 aggcaaaata tccttctttt agtcgcgacc aatgcatcaa ccctaaaatt aacccactaa
    16621 ccagcaacaa atacaacaca atacttattc caggaataag atacatttgc caattcgaaa
    16681 acgtacttaa acgtggataa aatactttcc aactaaacca acctaacaga atcaaaaatg
    16741 gaaacaaaaa gaaaccataa tagcaaaacc ataaataacg attgaaatag cgaattcgcc
    16801 gaccacgata cttgaaaaaa tgagctttca attgtcacat tcctcctttc tgtttttact
    16861 tttcctgtgc taaaaacttt tgacaaaaag caactaatac aggaatatca catttagtaa
    16921 aaaaacataa tcgaaaaaga tttaatcgat ttttataagg gtgtgcacac atattacata
    16981 ttcgtactat acgaatccaa atcacttcct gatgatcttg tttccactgg tacggtaatg
    17041 aaaaacgaac aagatcacgt aaaaacatac actgcccaat aaccgcacaa atatatgcat
    17101 ttgtttgtac aaaaatcgtt ggattgtctc caaaatactc aatcaattgt tggatatttt
    17161 gataacaagc acaatctctc aaagtatttg attggtttta tctgaattca aaatctcccc
    17221 ttccttctat cttagataaa aagaatagga agactccttc ctattctttc aaaaaaacct
    17281 tattttttct ctttttcctt agaatcaaca cttggttgtt tttgatctaa acctttttct
    17341 tgtgattgtt tcatattagg attatttgtt ggagcttcta ctttctctaa tcctttcgca
    17401 taaatcacta aatctgaata ttcacgattg ccatcttgtg ctggaatata taccacatga
    17461 tattctggat caattaattt cacaggatca cgtcgtttaa aaccagtcaa atctacatct
    17521 gctggaaatt taactcgtcg tgcaatcttt ggttcatctg gatttccaaa aactaattgt
    17581 gctcgctgtg atcgaatttc tcccgtataa tcgcctgttt cattatcaaa tacacgatca
    17641 gactcttcta atgcgccaaa gcgtacggct cctaaacaag tttcatctaa tgcttctgta
    17701 atgtcataat tatttggaaa ttttaatccc atcttacaaa acctccccaa tttttacacc
    17761 agttaaaaag acaccaacat cttgatagcc agttgttcga cgctctgttt gtcccatatc
    17821 atttgtttca cgactattca ctcgttcttt acgaaaaaca aaataagctt cttcaaatga
    17881 aatacgcacc tctttttctg gtaatcgtaa tcttttatcc tcttcagctg tgagataaac
    17941 aaaaaaagca ggctgttctt ctcgcgaaca ctctgcttgt aattgaacat atcgcccaga
    18001 cacaccatta atttcctttg gtggattagg ttcccgtgaa cccaataaaa atacttgacc
    18061 taaaaactct ttcttcatac gcaatgcttt ttctgccata aagtttttcc tcctcttaaa
    18121 aaccaaaata aattctaaat atttctacat tacaatcaaa caagcggtta aaaatcctaa
    18181 ccgcttgttc ctcatgacta atctttggct ttacgtactt tataaagtgt tatacctaaa
    18241 gcaatgacta atactactaa tccaagaacc ataagtatac tacttgtttg ttcacctgtt
    18301 tttggcaaca ttggtacaac agtagctggt ttaacccgtt gttctggttt cactggttgc
    18361 ggtggttttg gcgcttccac aatttgaacc gtttgatctt tgtttgttag atctacattg
    18421 tgtttcgcca cttcttcaaa cgtttctttc tcatcttccg ttttcgcttg gagccattcc
    18481 gcaaaactca agccttttcc tgcaagattg cgaccgtcca ctaagaattc aaataagaat
    18541 tccatcattt ctttatcggc cgcaaagact ttttccgcat gagtgccttc aaatggtgtg
    18601 ccgtctggtg ttaagtagcc ttgaacaatt aagcgataga tttgaccaat cgcaagaccg
    18661 tctactttga cccattcaag cacagtttga tttggcaagg ccaagatctc ttttccgcca
    18721 tttttattcg tcgctttcgt cgtaatggtt ggattactga ttttgatggt ttggtcattg
    18781 tcggtaatat ctgcgtgaga agccaataat acgccttctc taaacagatc ttcaaagacc
    18841 acgacttctt tgcctcgcaa cgcacgtgcg tctagaataa agtctagatt gactgtacca
    18901 tccgttgttt ctgccacaaa cgttaaggta cttgtgactt cttttccatc tactagcact
    18961 ggtttttccg ttactttgtc cattagaaca ccgttgactg tgtatgtttt tccaacgacc
    19021 aaatcgtggt atttcacagc gtctgtaatg gtgactttcg ttaatggatt aacctctttc
    19081 aagccagtgg gtttatgtgt agccgttgta cgtacacttg ggttagttac tcgtaccgtt
    19141 tgccctttgt cgttgatgtc tttatggttt gctagttctt catcatttct aaaaagactt
    19201 tcaaacacga cgatttcacg accatttata cctgtcaaat caaaggtaaa tggtacgatc
    19261 accgtttcat tttctgcttt ggcaataaag ccaacactcg tttctaccgt atttccatgc
    19321 acaagcaagg gttcaccggt tgctttatcc attaagatcc ctttgaccaa gtatgctttt
    19381 cctggaagaa tctcggtaat ttcaacggta tcgtttaagg taaacaatcc tgttgggtct
    19441 gcgactgtca atccgtcttc aaagacagcc gtggtatgaa cggttggatt attcactttc
    19501 acactttggg cttcatcgtt gatatccgca tgtgctgcaa cttcaatgcc atcacggaaa
    19561 agtttttcaa aaacaacgat cgtttgacct ttcagaacac tagcattaac cacaaattca
    19621 aggtcttttg tgccattgac tttgtctgca ataaaggcca aggtacttgt gatttctttg
    19681 ccatcttgta aaattggcgc attcgttgcc ttgttcatca atactcctga aatggtgtat
    19741 tcttttccga caaacaagtt ggtataagaa acactgtctt taatgacgat cgtttctaat
    19801 ggatcaacca ctttttcacc atcggcttta tttgacgctt gtgtttctag ttttggtgga
    19861 atcaagtaat tacgtacaga aaccactaac gtttccccat catctggcgc attttgtttg
    19921 aatgcaaccg tgaatgcttg tttatctgta tttggttgga aactttctaa tggggcattt
    19981 tccaagaagt aatagtcatc ggcaactaga cctttcacta aaatttcccc gttttgatca
    20041 gtggtatatt caccaattgc ttgattttta ccgttataca aggtaaagtt cacacctgcg
    20101 agcggcgttt tcttcttgtt ccattcttca tacttgaata attttacact tttccgtgct
    20161 tgacggttcg caaaatggat cactttgatc ggttctgtat cattggtaat cgagaacact
    20221 aatgggtttt gattcaaaac gtaatttacg ggggctttga tttcttccaa acgatagcga
    20281 tcttttccat aagtaagtgt accgttagtt aggaaaaagc ctttttcatt ggttttaaag
    20341 atatccgttg tttctgtatc atttggaatc tccattgtga cataacgatt ggctaaagta
    20401 tcaaaaatct tgaattctgt attagcaagt ggaatcactt ttcctgtttc ttgatccact
    20461 ttcaccactt taagacgttg ttcaattact ttatcttcta aaacataatg gaaagtttgc
    20521 ccattttcag aaattgtgac ttcaagtggt tcaaatagtt tatacccttc ttttcctttg
    20581 gtttcagaaa gaatgtacgt atcaaagaca acggtatttt taccaaaagt agcataacca
    20641 tcattgtctg tcacaacggt tttcaccact ttgccagttg tttttgacgt caaagtgatt
    20701 tcaatgccag ctaattttgg tttgttatct ggattcgttg aatcgactaa atctttatta
    20761 gcaactttca ctaaatcaat ggttcctttg atcacttgat cttttgcggt cgcattgaca
    20821 gtttttccag gttcaacaac aatttcaatt gcttcatcag aaagcacata accttttggc
    20881 gctttgattt cttttaaaac atatttgcca ggatcaagat ctttaatttc tgcctgtact
    20941 ttgccgttaa tttttttcaa ggtaatttct ttaatctttt tcccatctgc ttgatacaaa
    21001 ccatagaccg cattttctaa agaagctgca ccttgtgctt tcacaccagt ttccgcatct
    21061 tctttaaaca cacgaatgtt tccttgtttt agaatttgta aattaataac agacgcatta
    21121 ggttctgttg gatgtaacac accaattgtt tgagctcctg gacgacgata ggctaatggc
    21181 gcaccttgaa ctttaatttt attcaattga atttttgctt tatccggtgc ctcttttgtg
    21241 actgtaatcc atacttcatt gccgtgaata gatacattga caccttttgg tttttgaatg
    21301 tctttcacat atttcaaaaa atcattttta ttctttactt tcaacgtttc gccaattttt
    21361 accgtatgtg tttgattatt aaaagttgct ttttcaccaa agttattaat caaacgttga
    21421 atttctgctt ttcgacgatc ataatcaaca cggatatttt tgattgggat ttttgtgccc
    21481 aaagcttccc aaatcataaa ttgtgccgca atgtattgtt catcggattt gtctttattt
    21541 gtgacatatc ctaaataaga gatcaagctt gtttttttcc gtacatttga atttttcaaa
    21601 tagtttttca aagcagtagc tgtataaact tgaccttctg cggctgagac accaggctca
    21661 atacaaaacg ccacttgtcc attaatctca aaacgaacca tataatttaa agtgaagttt
    21721 agattgttcg gactagaagt aacaccaata ttttcgcccc aatcaatttt ccgaccacct
    21781 aaaacagctg cattggttgc acggcgaaca cgaaccgaac gattggttgg tactgttact
    21841 aacagtgtag gtgtacctgt ttttggaatg ttctgctctt ttttcttttg attttcaata
    21901 ctagccgtag attctttgtt tggtttcgtt ggttgatttt gactagctgc ggttgaagag
    21961 attgtttttt caacgttttc ctcatttttt ccttctttgt cagcagtagc cgctggttgt
    22021 tccactgttt cttctattcg tttcttttct tccgcttgtt tctcagaaga ctctggctgc
    22081 acagaaggcg ttgcttcggc agctttttct ccttctagag tggacgtttc tgaagcaggg
    22141 gttgtaattg aggcagtttc ttcaactggt tgtgaagtac caggactatt ccctgggtgt
    22201 tgtgtttccc caatcgtctg atcgagagtc gttttggaat tgaccgttgg cgcttctgtc
    22261 acaggggcct gttcaacagt ggcttcacca gctgggaccc cggcttctgc tggttggact
    22321 tctgtcactt cagaagcgac ttgggcaatg gcttccatcg taggttgtat agccgtcgtt
    22381 tcttctgcat gtgcttgagc agttcccacc aagaaacaga attgagaaaa agccaccaat
    22441 gcgagtgctt tcaaccaatt cattttcgtt tttgcataca caagaattcc tccttttcct
    22501 gagaatttta tataataaaa caaaacgccg ttaccaaaag tgataacgac gtgaactgtc
    22561 tcttctattt ttatctggcg ctcttatctg aacacatttc atcaatgatt ttaccctccc
    22621 actataatta cagaacaaaa aaagaacctg cttcgtggaa atcaactgtc catttcccaa
    22681 ttggaatacc agcttttttg gcaacttcac catcaccaaa tctcatgcca taccaattac
    22741 taccttcatc cttaatttct ttccaaccat atgacatagc ttcatctaat gaatcaaaaa
    22801 tcatgacact attgccaatt gttacaggat ctggcttaag atcttctgga agagaaatat
    22861 caatcatacc ataatgatcc gattcctcag tattattgtc attactagct actggtttgg
    22921 ttgttctact ggcttatttt gatacaacaa gtactcttat tcttctttta cttctccgtt
    22981 ttcaatttcc cattcaaacc actccgcaaa gtcttgctta aaaccatcta ctcgatacct
    23041 attttgtaaa taggcatctt ctgacgtcgt aggatctaaa taggtaggtt tattctctgg
    23101 acgagcatag acacctaccc atgtttcgta atctccttca aaataactat ctaccaaata
    23161 gccttttttt ctaagaatct cccgaacttg atttttaatt attgatactt gttcaaaacc
    23221 atcactcatt ctatcacctc aaataactct agattctcat aaatattccc gacaatttca
    23281 atcctatcaa tgatctctaa caaatcgcta cttatgcttc cccattcgta taagaatttc
    23341 ccttccgcaa aataaatttt ccataaactt cttcatgatc gtcccaacca atatcactct
    23401 cgaaaaattc cacgttgttc ttatctttta gctcagtaaa tgccataagt tcaacatgtt
    23461 ttccaacctc gaaacaatca caccacccat caaccgttac acgtgtgcct tcaataccta
    23521 agaaactttg tcctcgtgta ttaaacacta aaactttccg cattttttgc tcattaatta
    23581 atcacgcgcg aaatctagga atcacaactt attcgcttct tctttataaa taaaaaaac
//
LOCUS       DADVXK010000035        22797 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.035, whole genome shotgun sequence.
ACCESSION   DADVXK010000035 DADVXK010000000
VERSION     DADVXK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.035"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            83..493
                     /locus_tag="KB909_001308"
     CDS             83..493
                     /locus_tag="KB909_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBB6837352.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            486..1187
                     /locus_tag="KB909_001309"
     CDS             486..1187
                     /locus_tag="KB909_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBB6837353.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            1187..2773
                     /locus_tag="KB909_001310"
     CDS             1187..2773
                     /locus_tag="KB909_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837354.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2792..3013
                     /locus_tag="KB909_001311"
     CDS             2792..3013
                     /locus_tag="KB909_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBB6837355.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            3010..3771
                     /locus_tag="KB909_001312"
     CDS             3010..3771
                     /locus_tag="KB909_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBB6837356.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            4151..4660
                     /locus_tag="KB909_001313"
     CDS             4151..4660
                     /locus_tag="KB909_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6837357.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4735..5274)
                     /locus_tag="KB909_001314"
     CDS             complement(4735..5274)
                     /locus_tag="KB909_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBB6837358.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(5414..6025)
                     /gene="rpsD"
                     /locus_tag="KB909_001315"
     CDS             complement(5414..6025)
                     /gene="rpsD"
                     /locus_tag="KB909_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBB6837359.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            6287..7138
                     /locus_tag="KB909_001316"
     CDS             6287..7138
                     /locus_tag="KB909_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBB6837360.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            7166..7801
                     /locus_tag="KB909_001317"
     CDS             7166..7801
                     /locus_tag="KB909_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBB6837361.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7821..8594
                     /locus_tag="KB909_001318"
     CDS             7821..8594
                     /locus_tag="KB909_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6837362.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            9002..9799
                     /locus_tag="KB909_001319"
     CDS             9002..9799
                     /locus_tag="KB909_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBB6837363.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9777..10190
                     /locus_tag="KB909_001320"
     CDS             9777..10190
                     /locus_tag="KB909_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6837364.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            10174..12819
                     /gene="mutS"
                     /locus_tag="KB909_001321"
     CDS             10174..12819
                     /gene="mutS"
                     /locus_tag="KB909_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6837365.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12837..14945
                     /gene="mutL"
                     /locus_tag="KB909_001322"
     CDS             12837..14945
                     /gene="mutL"
                     /locus_tag="KB909_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBB6837366.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14967..15527
                     /gene="maf"
                     /locus_tag="KB909_001323"
     CDS             14967..15527
                     /gene="maf"
                     /locus_tag="KB909_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBB6837367.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(15612..17600)
                     /gene="treP"
                     /locus_tag="KB909_001324"
     CDS             complement(15612..17600)
                     /gene="treP"
                     /locus_tag="KB909_001324"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBB6837368.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17823..18536
                     /gene="treR"
                     /locus_tag="KB909_001325"
     CDS             17823..18536
                     /gene="treR"
                     /locus_tag="KB909_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBB6837369.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            18613..19059
                     /gene="msrB"
                     /locus_tag="KB909_001326"
     CDS             18613..19059
                     /gene="msrB"
                     /locus_tag="KB909_001326"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBB6837370.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGVFKSLVE"
     gene            19229..19831
                     /gene="ruvA"
                     /locus_tag="KB909_001327"
     CDS             19229..19831
                     /gene="ruvA"
                     /locus_tag="KB909_001327"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBB6837371.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19844..20845
                     /gene="ruvB"
                     /locus_tag="KB909_001328"
     CDS             19844..20845
                     /gene="ruvB"
                     /locus_tag="KB909_001328"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBB6837372.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20874..21452
                     /locus_tag="KB909_001329"
     CDS             20874..21452
                     /locus_tag="KB909_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6837373.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            21504..21986
                     /locus_tag="KB909_001330"
     CDS             21504..21986
                     /locus_tag="KB909_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBB6837374.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            22103..22477
                     /locus_tag="KB909_001331"
     CDS             22103..22477
                     /locus_tag="KB909_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837375.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7416 a         4075 c         4932 g         6374 t
ORIGIN      
        1 gtatcttaga aacagcatgt tttgaaactt tcagaaaagg tttgttagta aaatgaaagc
       61 tatacgtaag gagtgttgtt tgatgaaatt ttttcaagag tttttcatta ttattttctt
      121 ttctgtatta ggagaaggca tacggatttt tgctcattta cctattcctg gaagtatctt
      181 aggtattctt tttttatttt tagcatttga aatgcatctt gttgatcctg aaaaaatcgg
      241 agcaactggt gattttttat tgaataatct agccatttta tttgttcctg ctggtgtagg
      301 tttattggaa tattttgatg atattgcttc gatatggcct gttttactgg gagcagtcgt
      361 cgtgtgttcc atcgtcacga tggttgcagc gggaaaaacg gcagaaggtg tagaagcttt
      421 gctgggctat gtccgtaaga aaaaagcaga aagggtatct gtaaacgaaa tggaggagaa
      481 tcaaattgac tgagtttttt gtgaatccat tatttggctt aagtttgact ttaggagtgt
      541 acgtattatc tgacaaattt ttgcggaaat ataaactgcc tgttttgaat cctctcgtat
      601 tatcgattgt tgttattatc ttatttttgc atttttctgg gatcagctat aaagactata
      661 atatcggggg caattttttg actatgctga ttactcctgc gacagtggca cttgccatcc
      721 ctctttataa aaacttccgt ttactgaaag agaattttta tcctgtaatg gctgcgattt
      781 tagcaggaat agtcgcaaat tgcttggtta gtgtagggtt cggttacttc ttctctcttc
      841 ataaagagat ggtgatctca ttactaccta aatctgtaac gacggctatt tctgtcgatt
      901 tatctcatac gatgggcggg gtgaatgccg tgacacttgc tattgttgtc tctacaggta
      961 tttttggttc gctgatcgcc actcatattt tccgcctatt caagatcgaa agtccagttg
     1021 ctcgcggtgt ggcgttagga agtacttctc atgctattgg tacagcaaaa gcaatcgaga
     1081 ttggtgaaat agaaggaatc atttccggac ttgcgatatg cgtcaacgga atattgaccg
     1141 ttttattgct accgttattc tttcagcctt ttgctggctt gttttgatgc gaaaaccact
     1201 attttatgct acaataacca aaacgttcga gcataaaaaa ggagggaaag acgtgtattt
     1261 gtcttccgag tatcttaaac aatttgataa agatctatat tataagattc tcctcctaga
     1321 aagttttgag gatcaagctt ggcataccgc tgcacaatta gcgcaagttg ttcagctgga
     1381 tgcccgcagc gtgtcgaaat acctgaacga gctgtctaaa aactatcagc agtttagcgg
     1441 taagacacac cctttgttta caaaaaatca ccgttctggt tataactttt atgatacgct
     1501 cgattcaatt gaacatgagc gttttttgat ctatctcgtg caaagtacgc tgaaattcca
     1561 gttgctgcac gacatttttt ttgaagaatt ccatacaatg taccaatttg cgcaaaagca
     1621 ttacattagt gaatctactg ctcatcgaaa aatcaatgaa tggaaacagc aactgcaaac
     1681 ttacggaatt cggctgcaac gaggtacata tatcgctcaa ggcgaagaag aaatcattcg
     1741 actttacttg catatgacat tctggcagtt gtttcgaggg aaaatctggc catttgaaac
     1801 gatttctcaa atggacgtaa agaatatggc agaacatatc atggcttttt ttaatgttcg
     1861 tctgaacgag atcaaaaaaa gacgattgga atatatgcta ggtgcctttt ttttaagaaa
     1921 atcacagaag cattatgttg tattgaatga gaaaaaaaga cggctgattt ctgacaatct
     1981 gttgttccag cgattttgcc aggtcatgga gccggtattt cctaattatt ttcaagtaga
     2041 agacgagtta ggcgcattat ttcttgtact gatgactcgt gaagaatatt atagtgatcc
     2101 taagatacgg aagaaaattt ttgattttca tcaacaagca aaaacaccgc cctttacagc
     2161 cctttcagaa gcaaaagccg ctctttctct ttatcaggaa gagcaggggc tgccagcaga
     2221 aaatctaacc ttcgaggcag aaaactattt attcagcagt cattttttcg cctatctttt
     2281 tcctaatgcg aaagaaacga ttgatggcaa tagtagtgat tttattaatc atttagttat
     2341 tgaaaacaag gaattgaaac aatggctcgt acattttttt gaaagtagac acaaacatcc
     2401 caatcatctg gcatttaaaa atcatgcgtt tttgatgggg cggtatctga ctgtgtttaa
     2461 aacattagga gcctttactc cacagcttcc aaagatcacg atccttttaa tgacagattt
     2521 cccattattt gaagagcaac tgttagagga gggattacgg acatttttcc gtaatgagta
     2581 tcagctgatt tttctgccaa cagattatcg ggggagagaa gttgatcttc tgatttcgac
     2641 aagtaaagtc caccgcaaac catgggcgga tcttgactat tttattgtga ctgaagaact
     2701 aaaattaatt gattacatcc aactatctca aaaatttgaa atgattcaaa aacaaaaact
     2761 attaaaacaa taacaaagaa ggagaaaaaa gatgacattt gaagaaattt taccagaatt
     2821 gaaaaaaggt gcaaagatta ttcgtaaagg atggagtgga tttgaacttt atgttgttct
     2881 cgtatccgat gatgaatttg atggctgtcc ggtgacgccg tacttattga tcaaaacaag
     2941 tgacgaaggt ttttccagct tcgctcctac agtttgtgat attttagcag atgattgggc
     3001 gatcgtagaa tgaaaaacca gtatccagat ctagctaaac aggttgtatt tatcacagga
     3061 gctgcttctg gaattggtgc tgcgcaagcc cgagcgtttc ttgaacaaga tgcttttgta
     3121 tttggattag atcaaaagtt cggtaaaatg gaagaaattt ctttgcgatt tcctgaaact
     3181 tttgcctacg cactaggtga tgttcgacaa atgaaagaac tccaacaagc ggtatcgaaa
     3241 tgccaaaatc attttggtga agttacgatt ttactgaata cagcggggat attggatgcc
     3301 tacaaaccct tgatggaaac tgacgaatcg ctgtgggatc tgatttatga gacgaatgtg
     3361 aaaagcatgt atcagctgac aaaaatcatc cttcctgata tgatccgcca aaaaagcgga
     3421 acgatcatca atatggcttc gattgctggc ttgattgctg gtggaggtgg gatcgcttat
     3481 acaagcgcga aacatgcgat tgtcggattt accaaacaac tcgctctgga ttacgcagga
     3541 cagggtatcc gagtaaaagg aattgctcca ggagccatcc aaacaccaat gaatgcggct
     3601 gattttgaag ggaaaggtga gatggcagag tgggtggcaa atgaaacacc agtcaagcga
     3661 tgggcacagc cggaagaagt agctgagctg acgttatttc ttgcctctcc tcaagcaagc
     3721 tacatacaag gaacgatcat cccaatcgac ggcggatggt tgttaaaata accttgtgtt
     3781 tttttcaagc ttctgtatga taaaactaaa gagagaaaca acggttgatg ataaaaaaag
     3841 tcgatgactg ttcccgacat tcgatgccga acagccagtt caaaaaattc tttttaataa
     3901 tcgttaatat tcgaaactaa gcggcttttc acgacctctt gatataaacg atattcaaaa
     3961 gcttgcaact gcggtaacaa gtccagccaa atgaaaaata taaggagcta tttttatttg
     4021 accattctta ttacttgttg cagggcagct ttttcactac cttctgcgac acttcagttg
     4081 gaattttctt cccatccttt ggtcgcggtc attaccaaga taaaattatc ttgcaaagga
     4141 gaaatagaac atggaaaaaa ataatacccg ttcagccaaa cgctggacaa cgacagatgt
     4201 gactcggatg gcgctagtca ctggtttata tgtggcagtg acgctggttt tgtctgtctt
     4261 tagctttgga gtgattcaga ttcgtctctc ggagatgttc aactatctgt ccttgtataa
     4321 caaaagatac atcgtcgcgg taacagcggg agtagctttg gctaatattg cttctcctct
     4381 tggactgata gatgttgcag taggaagcgt cagcacgctg cttgtattgc ttatcaacta
     4441 taaaatcact agtcgcatca aaaacatgaa aatcaaaatg gccgtgacag catgcgtatt
     4501 tgctttttcc atgtttacag tagctggtca gctaacgatt ttatatcaac tacctttttt
     4561 cttgaattgg tgggtgattg ctttaggaga attggcatca atgattgtcg gtgggataat
     4621 tatttattgg atcggtaaaa aagtggattt gtcaaaataa agatctgttt aatttaaaat
     4681 agggcagcat ggaagagact gaatgttgag tcttcttcca tgctgctttt ttgattaatt
     4741 tgtatgaaga aatcgattta gccgtttttt catcaagata ccgatataag ctgctccagt
     4801 tgccttgatt gcttccggca gtaaaaacgg cagtagtcca ctggcaaatg cagttgtaaa
     4861 agtaagatca ccacttattt tcagccagat cgttccgcag atcaatgcag caagagagcc
     4921 cattagattg gcaaagattg catataagta atgagcatcc gttctttcga tcatccaacc
     4981 agttatccac gtttgtaaga gaaatccaat caaatatccg ccagttggcc caaataaaac
     5041 agctatacct ccagtcatcc ctgaaaatac aggaagacca atcaagccaa gtaaaagata
     5101 aactccaaca gatatcaatc ctagttttct tccgagaaaa gttgctgtta atccaatagc
     5161 aaatgtttgc cctgtcaaag gaaccaaacc aaaaggaatg gtcatctgag aaaggacaga
     5221 aataatcgcg gcaaattccg cagcaagtat caattctttc aatgttcggt tcataacgcc
     5281 ctcttttcgt taacttaata tttttatttg gttaacgaaa ttgtaaaaca aagtgattac
     5341 tttgtaaata gaaaatataa aaaaagacca gctatccaat agatagcggt ctttttcaag
     5401 aaagcttttg aaattataag ctttggttgt agtattcaac gacaagagct tcgtcgattt
     5461 ctggatatag ttcgtcacgt tctggtaaac gagtcaatga accttccaat ttttcagcgt
     5521 caaagcttac gaatgctggg cgtccaacag ttgcttctac agcttctttt actgttacga
     5581 tgttttgtga tttttcacga actgagatca cttgacccac ttctacgtgg tatgaaggga
     5641 tatcaacgcg tttgccatca actaaaatgt gaccatggtt aactaattga cgtgcttgac
     5701 gacgagtcgt tgcaagtcct aaacggtaaa caacattgtc taaacgttgt tctagtaaga
     5761 tcatgaagtt aacaccatgt ttaccttctt tgattttgct agcttttacg aacaagttac
     5821 ggaattgacg ttcgttcatt ccgtacatgt gacgaagttt ttgtttttca gttaattgca
     5881 tgccgtattc tgattgtttg ccacggctat taggtccatg ttgacctggt gcgtaagggc
     5941 gacgtgctaa ttcttttcct gtgcctgaca atgagatgcc taagcgacga gaaattttcc
     6001 atgatggtcc tgtataacga gacattaaaa tttcctccaa tgaatataag tttttggagt
     6061 aaaataatcc gttgaaaaat tcataatcat atagtttgtt cttcaatctt cacctttgca
     6121 gccgcggtta cacaatcgaa cccgagacgg ggcaacaaac tagggatgag ttattatttt
     6181 tctgctgcat tattttacac aaattacagt atatgataga tcatccacga atgtcaagat
     6241 aattagtaca taaaaacgct ttacaaacct aggctgtctt tataaaatga gagggtatgt
     6301 gcaaatggaa aaaagcgaag gaagtttaag gagaaaatca atgaatccgg tatcaccatt
     6361 atttgagaaa atcgatgctt caattgaaaa gaaggcgaat ctttttgaaa acagcttttc
     6421 acgttacgct gttcgagcgg ttctcgcctg tttgtttttg actttaggaa cggctgtggc
     6481 atttgcgatc gcgatgaagg gggaagatat cgcgcatggt ctaggaaaga ttttatacgc
     6541 atttatgttc agctggggtc tggtcatgat tctatacatg aacgccgaat taggaacatc
     6601 gaatatgctt tatatgaccg tgggtgtttt tcggcagaga cttgctttaa gtaaggcagc
     6661 caagattcta tttgcctgta tttttttcaa tatgattggc ggtatattat gtggatttct
     6721 aatttctatg actacgccat ttcaagattt aacgttggac aactttatgt tagaatcaat
     6781 agcagtaaaa ctagcaaaac cttcagcaac gattttggtg gaagggatgt ttgcgaatat
     6841 cgttgtcaat accgctgtac tgatcagcat gcggatgaaa gaggatgtcg gaaaagtgat
     6901 cacagtcgta ttcatcattt tcatttttgc ttttttagga tatgaacacg tgatagcgaa
     6961 ttttcctgcc tttacgctta cttactttgc ttctcacgga cagatggatg gaatgacagt
     7021 cagcaatgtg ttacataatt tgttttttgc tttggcagga aattatattg gtggcggttt
     7081 agtaatggga ctgggatatg cttggctgaa tcagtcaaaa tcatcctatg tggactaaaa
     7141 agtcgttcat taaaggggaa gtgccatgga agttttagtt tttccaaaaa atgaggaaaa
     7201 agcgttacaa atggaaaagt acatgaaaaa tcttttttcc tttgctggag tacctaagcc
     7261 ggaacgcgct cttttacaac aaccgttact ggatgagagc aaaaatttat ctatttctga
     7321 agttttagct tttgttcatt attattatga acaaatcgaa agagagtatc agtatgtagc
     7381 gatcgattta gtccagaaaa acatcaaacg gcttacattt gaagacttag tcgtattgtt
     7441 gccactagtt cagaaaaaag aatggtggga cagcatcgac tcttggagaa aagtatacag
     7501 cacatggtgt aaagcctacc cagagcagcg tgaagaagtc tttcaattgt ttgaaaaaaa
     7561 ggaagatttt tggctacgtc gaatagcaat cacgttgcaa ttaggttata aacagcaaac
     7621 agacacagga ctattgatcc gagcaataga cgaagatcgt caaacaaagg aattctttat
     7681 ccaaaaagca attggttggg cattacgcga ttatagtaag accgatgccg attgggtaaa
     7741 aagacagctg acaacagatt tgagtaagtt agctgttcga gaggcaagta agtatttata
     7801 agaaagcgag acgacaagag atgagacgca aattatttgc ttttgatatt gatggaacgt
     7861 tgttagattc aaacaaacaa gctttagata gcacaagaga agcattggaa aaattacgca
     7921 aagccggtca tctggtcacg attgctacag ggcggagccg atttcatgcg caagagatca
     7981 ttcgcgatct tgattttacg aactacattt tatgtaatgg agcggccggt tttttagacc
     8041 atgaacaagt atataagaat ttactagatc gcgaccagtt ggatgcgttc gttcaagaag
     8101 cgcatcatga gcagatcgat acagcttttg tcagcttaga caatatcaag cgttcttctt
     8161 ccaatgatgt aacggtgatg gaagaagcga tgcattcttt cggtgctgtc ttgcctgaat
     8221 tagatcagtt ttttgcagag gaacaagaaa tataccaagc gttagcattt ttcgatcaaa
     8281 catatgatgg gaagttctct tcatatgata aaattcgatt tgtccgctgg catgagaaca
     8341 gtgtagatgt cgtacctaaa aatggttcta aagcagcgac aattctgcac ttagcagaac
     8401 aagtaggcat ccctcatgaa gacatcatca gctttggcga tggacaaaac gaccgtgaaa
     8461 tgttgcgcat gtcaggaatt gggatagcta tggggaatgc tgtgccagaa gtacaagcag
     8521 aagctaagat ggtcactgat acaaacgatc aggatggaat ttggaaggca ttgaaagagt
     8581 taagcgtgat ttaaaagagg ttgtgaaaaa gctgttctgc atcaagtaat aagcccagcc
     8641 aaacaaaaat agctcctcct atttttcgtt tttctgggct tattaccgca gatgcaagct
     8701 ttcgaacacc gtttaaggaa gaggtcgtga cagaagtggt cagtttcaag aaataagaag
     8761 ggatttacga aaattgcttc tcaaattttt gtaaaattac ggcttatttc tgaagaagta
     8821 gatgaaacaa cgtttattcg ggaaatggga ctgtgacaag atgtttgtca tagtcccatt
     8881 tttttatttt atttttcaaa actaagaaat accaggaaag agttcctttt gtttgacctt
     8941 ttctttctta ttgaaaacaa ctataatata gagtgatgtt aaaagagaag aggaatttag
     9001 tgtgcgggta ttgtttattg gtgatgtagt aggttcaatg ggacgagaga tgattactga
     9061 atatcttcct agattgaaga agaagtaccg tccgcaagta acgattgtaa atggtgagaa
     9121 tgccgcttct ggacgtggaa tcacagaaaa aatctataaa aaatttttgc aagacggcgt
     9181 agatgtcgtg acgatgggga atcatacgtg ggacaaccgc ggaatctttg agtttgtaaa
     9241 tgaagctaaa aagatggttc gtccggcaaa ttttccggaa gggacgcctg gacaagggat
     9301 ggtctttgtc aaagtgaacc aagtcgaact ggcagtgatc aacatgcagg ctcgttcttt
     9361 tatggtggac ttggatgatc cttttcgtaa aatgaatgag ctggtagaag aagccagaaa
     9421 acgtacgccg atcatttttg tagattttca tggagaaaca acaagtgaaa aacaagcaat
     9481 gggctggttt ttagatggga aagtttcagc agtggtcggt acacatacac acgttcagac
     9541 aaatgatgcg cgaattttgc caagaggaac agcgtatctg acagacgttg ggatgacagg
     9601 tccctatgat ggtattttgg gtatgcgcag agaacctgta atcgaaaagt ttctgactgc
     9661 attaccaaaa cgttttgaag ttgtggaaca aggccgatcg attttaagcg gctgtatctt
     9721 ggaattggat gatacgacag gtcatgcaaa agaaatccag ctgattcaga tcaacgatga
     9781 tcgaccgttc atggagtaga aagagaggca gttttttgca gcaggagccg gaaattcaaa
     9841 aagaagtaag gaaactgaca aaacttttaa gagagaatga aacgatcatt cgctacaaag
     9901 aacttgaaga aaagatccag caaaaccagt atttagctga gttgagagaa aaaatcaaac
     9961 aagcgcaaaa agatgctgtt cattttgccc actatgacaa accagcagca gaaaaagaag
    10021 caatcaaaca agcggatcaa ttcatgcaag aatttgatca gcatccgctt gttgtagctt
    10081 atagaaaaca gctgttggaa gcagatgatc tgcttcatca tttaacaact atgatacaag
    10141 aagaaatcaa tggacaaata gaggaggaaa aacatgcctc aaaaaactaa aaatactcct
    10201 atgatggaac aatatctaag catcaaggcc caataccaag atgctttttt gttctatcgt
    10261 ttaggagact tttatgaact attttacgaa gatgcgatca aagcgtcaca gcttttggaa
    10321 ttaacgttga cgagcagaaa tcgaaatgca gaagaaccta ttcctatgtg cggtgtacct
    10381 caccatgcag cacaaggata tatcgatgcc ttgattgaaa aaggctataa agtagcgatt
    10441 tgcgagcagg tagaagatcc aaagacgact aaagggatgg tcaagcgcga agtgatccag
    10501 ctagtcactc ctggtacagt catggacagc aaaggattgt cggcaaaaga caacaatttt
    10561 ttaacagctg tagttagtca aggaaatgaa tttggctttg cttatgccga tttaagtacg
    10621 ggagaattga agacggctcg gttgcatgat gaagaagctg ttttaaatga agcctctgca
    10681 ttgcagacaa aagaactcgt attaggcagt gagatcactg atacccttcg tgaacagcta
    10741 agcgggcgtt tagggctagt cttttctcaa caaaatgaga tggaagaaaa cgcggaattt
    10801 agctttttga caagcgaact agtcgatccg ctggaaaaag aagcaaccgg caaactattg
    10861 acttatttat cggtgacaca aaagcggagt ttagctcata tccaaaaagc agtagaatac
    10921 caaccagatc attttttgaa aatggattat tattcaaaat tcaacctaga attaagccaa
    10981 tctattcgga ctgggaaaaa gcacggcact cttctatggt tgttagatga aacaaaaaca
    11041 gcaatgggtg gccgtttact aaaacaatgg ctagaccgtc cgcttatcca ggcaaaacaa
    11101 attaaagcaa gacaagaaat ggtcgcttct ttgctagaca gctattttga acgtatcgat
    11161 ttgcagtcag cattaacgaa agtctatgat ctggaacgcc tagcaggtcg agtagctttc
    11221 ggtaatgtca atgggcgaga cttgatccag ctgaaaactt ctttagaaca agtgccaatg
    11281 atcagagggt tgattgaagg aatcgatcaa ggtcaatggc aaagtctgct ttcagaaatg
    11341 cagccgatgg accatctcgt ccaattgatc gaccaagcta tccaagatga tccgccgtta
    11401 caaataacgg aaggaaacat catcaaagat ggattcaatg agcagctcga tatgtaccgt
    11461 tctgctatga gaaacggaaa gaaatggttg gcagaacttg aagcaaaaga gcgtcaagaa
    11521 acaggaatca agaacttaaa aatcggattt aaccgcgttt tcggttatta tatagaaatt
    11581 acaaaagcaa atcttggaaa tgcagaactg gagaagtatg aacgaaaaca aactttagca
    11641 aatgcagagc gtttcatcac accagaacta aaagaattgg agacacaaat cctcgaagca
    11701 gaagaaaaat ctgttgattt agaatatcag ttgtttttag ctgtgagaga agaagtcaaa
    11761 aaggctatcc agccgctaca agtacttgca aaagcaatca gtgcagtaga tgtgctacaa
    11821 agttttgcaa cgatcagcga acgctatcag tatgttcggc cagaacttgt cagtgacaag
    11881 catcagcttc tgatcaaaga cggacgacat cctgtagtag aaaaagtatt aggacatcag
    11941 gaatatatcc ctaacagcgt agaaatggca gaagacgaaa tgatcttgct gattacagga
    12001 ccgaatatgt ctggtaaaag tacgtatatg cgacagttgg cattaactgt tctgatggcg
    12061 caaatgggct gtttcgttcc ggcaaaacaa gcagttttac ctatttttga tcggattttt
    12121 acccgaattg gtgcaagtga cgacttaatt gctggacaaa gtacttttat ggtagagatg
    12181 atggaagcca atcaagccct gcgttatgct acgccaaaca gtttgatttt gtttgacgaa
    12241 ctagggcgag gaacagcaac ctatgacgga atggcgttgg cccaagcaat catcgaatat
    12301 atccatcgtc atgtacaagc aaaaacactc ttttctactc attatcatga actgacggta
    12361 cttgagaaag aacttccgca gcttaaaaat gtccatgttg gagccgttga aaaagacgga
    12421 gaagttgtct tcttgcataa aatgatggat ggacctgcgg ataaaagcta cggcatacat
    12481 gtggcaaaga tcgcaggatt gccttccaat ctactagaac gagcagcaga tatcctgcat
    12541 acgctagaaa atggcgataa cggacaccat actgttccag ctgaagtaga agagaaaact
    12601 aaaacagcca aacaggagca aataaaacca cctgcagaaa aagtaaatca agaccatata
    12661 caagaccgtg taaaagaaga aaaccaacag ctttctttat tcagtgaatt atccgaaaat
    12721 gaaacagaag tcattgaatc actgaagcaa ataaatttac tagaaatgac gccaatggat
    12781 gcactaaaca cattatatga attacaaaaa caactgtagg aagaaggcgg atatcgatgg
    12841 ccaaaatcca agaattatct gaacgtttag ctaatcagat cgctgcggga gaagtagtgg
    12901 agcgaccagc ttccgttgtg aaagaattag tggaaaatgc aattgacgcc ggcagtactc
    12961 agattgatat cttagttgaa gaagcgggac tgcggacgat ccaagtgatt gataacggag
    13021 aaggcatttt ggcagacgac gtagagaatg ccttcaagcg gcatgcgaca agtaagatcc
    13081 ataatcgcga cgatcttttt cgcatacgaa cgctgggctt tcgaggggaa gctttgccaa
    13141 gtattgcctc tgtttctgaa atgactctgg aaacggcgaa tcaggaagaa aaacaaggca
    13201 cctatctgtc gctgaaaggc ggagaagtta ttgagcatcg accagcacca ctgcgtcaag
    13261 gaacgaagat taccgtcagc aatctgtttt tcaatacgcc agcccgcttg aaatacgtga
    13321 aaacactgca cacagaatta gcgaacatcg gggacatcgt caatcgactg gcattgagtc
    13381 atccatcgat tgcttttcgt ttagtacatg atggaaacaa aatgctggca actgctggaa
    13441 atggcgatct gaaacaaaca attgcgggaa tctacggatt atctaccgca aaaaaaatgc
    13501 tgaaaatcga aggaaaagat ctagattttg agttatttgg ctatgtttca ttgcctgagg
    13561 tgactcgtgc cagtaggaat tacttatcga cgatcatcaa tggacgtttt atcaagaact
    13621 tttccttgaa taaagcaatc gttgcaggtt atgggtcaaa attaatggtc ggtcgtttcc
    13681 ctattgctgt attggaaatc aaaatggacc cgcttttagt agatgtaaat gttcatccga
    13741 cgaagcagga agtccggctg tcgaaggaaa aagaactaac agagctaatt agtaacgcca
    13801 ttcaaaaagc attgtctcaa gaaaatctga ttccaagtgc agcggataat ctacggttta
    13861 agaaaaaagt acctgatcag cctaaaacag aacaaatcga aatcgatttg tcctacgctt
    13921 ttgaagaaga aaaacctaaa aagccaagta gtttgaattt tgatcgacag acaggtacct
    13981 ttttcgtaga agaactaaag aacacatttg ttgacagaat tgttgataag tctgtggaaa
    14041 atgttgaaaa ctattctggt ttttctgaag aaaacaccac ttatccagaa aaaacagcga
    14101 aaacggtgga taagtttggt gaaaatgttg ataactttgt agaaaaaaca gtggaaaaat
    14161 ctgaaaagaa agaatttccc attgtggata acatggagaa aacaaatgaa gaacaagcag
    14221 ataaatccgt agaagaggat gaaaagattt acgaggaaga attgacactc catcctgaat
    14281 ttgatttcac tcaaggaaac gacaaaacat tagaacaagc catcaagaaa ttagaaacgg
    14341 aaaaaccagt acaacgtttt cctcagttgg aatattttgg acagatgcac ggaacgtatc
    14401 tttttgccca aagtagcgat gggttgtaca tcattgatca gcatgctgcc caagagcgca
    14461 ttaagtatga atatttccgg gaaaaaattg gggaagtatc tgatgatctg caagaattgc
    14521 ttgttccatt tgtgttagac tatccaaaca gtgatgcttt gaaattaaaa gagcaaaaac
    14581 acttgctaga agatgcaggg atttatttag aagaatttgg tcaaaacagc tttattgtac
    14641 gggcccatcc tacttggtat cccaatggag aagaagaatc gattattcgg gagatgatcg
    14701 atatgctgct gacaactgga agtgtgagtg taaaaaaatt ccgtgaagca acagcaatca
    14761 tgatgagttg caaacgatcg attaaagcca accattattt gaatgaagca caagcacgtg
    14821 tgctgctgaa ggatctggca cgatgcgaaa atcctttcaa ttgtccccat ggccgtccag
    14881 tattgattca ctttaccaat tcggatatgg aaaggatgtt caaacgaatc caagacccgc
    14941 attaagtcaa agagaagagg gaaaacatga agattgtatt agcatcccaa tcaccaagaa
    15001 gaaaagagtt attggctcat atcgtttcag aattcgagat tgaacctgct gatatcgatg
    15061 aaacgccatt tccagacgaa cagcccgtcg attatgttcg tagaatggct gaagaaaaag
    15121 cacgaactgt ctgggaacaa gatgaaaaag aagaccattt agtgattgcc agtgacacga
    15181 ctgttgttct caatcaagag atcatgggta aaccagaaga tctggctgag gctgaattca
    15241 tgctgaaaaa actaagcggg gaaacacata ctgtatatac agctgttgtt ttaaaaacaa
    15301 aggaacgaga agaacggata ctagcagaag cacatgtcac tttttatcct ttgacagacg
    15361 aagagatcaa acgctacttg gagacggggg attatgcgga taaggcaggg gcatacggca
    15421 tccaaaatgc tgcgagtgta ttcgtcaaag aaatttctgg agattattac agtatcgtag
    15481 gatttccgat tggtgctgtc aatcaggcac tgaaaacatt catttaaaca aaaaagcgga
    15541 ctatctgatt ttcgattgaa aatccatgat agcccgtttt ttttattgaa aagattactt
    15601 atctactctg actaagattt tacttcagct ttaccgactg cttcgcccgg gcgaacaagt
    15661 cctgattggt caagagaaag tcctgcaact ttttcattat tggtcaaagc aacaataatg
    15721 tcagttttct tgccagcttg ttctatttct ggcaaatcca tttcagcaat cagggtctct
    15781 ggtgtgacaa ggtatccttc tttcacgaat acattgaaag gaacaccctt tagttcaaca
    15841 gtatctaatc ccatgtgaac aagtacttcc agcccctcat tagaaagaat accaatggca
    15901 tgttttgttt caaagacact cgtcacttta ccgtttactg gtgcatagac tttgccgttt
    15961 gacggttcga cagcataacc gtcacccatc attttttgtg agaaaactgg gtcatttact
    16021 tcagttattt ccttgatggt ccctgcagcg actgcgaata atgtttcttt tgttgcaact
    16081 gccgtaccag ttgctgaaac aggttcgaaa gactgtggcg ttgctgttgc gccatttgct
    16141 gtttgaagtt gtacatcagc agcattttca ggaacagcag gatcaatctt attcaaaatt
    16201 ccctgacgtc taaagatgat cgtcaagcca aatggaatga tgacagcaat gatcattgcg
    16261 atgatgaaag gtacccatgt ttctgcttgg atagctagta ttcctggcaa accgcctact
    16321 ccgatcgcgt tagctcgaac acccatcaag ttagcaaaca tgccagctaa tccagagccg
    16381 accattgcag cgacgaaagg atagacgtat ttcaaattga ttccgaacat agcaggttca
    16441 gttacgccta agtaacaaga aatcattgct ggaatcgaga tttgttcttc ttttttattc
    16501 ccacgatgta agaagatgat ggctaagact gcagagcctt gggcgatatt tgataaagca
    16561 atcatcggcc ataaattcgt tgatccgaaa tctgcaatca gctgcatatc gatggcattg
    16621 gtcatatggt ggagaccagt aatcactaaa ggagcataca ggaatccgaa tacggcacta
    16681 aacaaccagc tgatagaaga cgtcaatcca gtatttacga tatttgagat ccagcttccg
    16741 actgtccagc cgataggacc taaaataacg tgtgcagcta aaacagttgg taacaatgaa
    16801 aacaatggaa caaaaatcat cgagatcgac tgagggatat atttgcggaa gaagatttct
    16861 agatacgcta acataaaccc tgccagcatg gctggaataa cttgcgcttg ataaccaatc
    16921 atctggactt gagcaaaacc aaaatcccaa aatggaatat ctgctgcggc tgtggaagct
    16981 acactataag catttaataa ttgcggagaa actaacgtaa ttcctaaaac gattcctaat
    17041 atttgtgtag tacccatctt ttttgcaata ctccaagtga tacctactgg aagaaaatgg
    17101 aaaattgctt caccgggtaa ccacaaaaag gcattgacac cattccaaaa cttcgagtgt
    17161 tcaacgattg ttccaccaag actttcaaac tggatacctt caagtacatt tctgaatcca
    17221 aggatcaatc caccgacaat gattgcagga atcagtggtg taaagatttc tgctaaaacg
    17281 gcaatagcac gttgaacggg atgaaggttt tgttttgcag ctgcttttcc ttgttctttg
    17341 gaaacccctt caactccaga tactgcaacg aagtcgttat aaaaagtaga aacatcgttt
    17401 cctatgatga cttggaactg tcctgcattc gtgaacatcc cttttacgct aggtatatct
    17461 tcgatcgctt tttcgtccgc ttttcctgga tcattcagga caaaacgcat acgagtcgca
    17521 caatgactaa ctgcagcaat attttctttt ccgccgatat catgtaacag cttctcggca
    17581 tctgcttgat attttgccat atcaataaac ccctttctct taacttgtct atgcaagttg
    17641 tttcttcatt tactatactt tttttcggag agaattgcaa gcgttttatt aaaaagtacg
    17701 agagaaaatg atatcgtttt aaaaagctta aaataagctt ttcttaaaaa taggaacatt
    17761 gaaatacaaa aagagctgta gtatagtgaa gaaatgatgg aagaacgagt gagggaaaaa
    17821 acatgaataa gttcaatgaa atttttttag atttggaaca gaaaatttta gcgaaagaat
    17881 atcctccgca ttcgctttta cccagtgaga accaattgat caaaatttat ggtgtttcac
    17941 gagaaacaat tagaaaagcg ctgaatcttt tgactacgga aggttatatt caaaaaaaac
    18001 aaggaaaagg ttcgatcgta ctggatcgga atcgcttcga ctttcctatt tctggattga
    18061 ctagctataa agagctacag gagacccaac gtattccaag tgaaacgatc atccatacgt
    18121 tagaagaaac agaagtgaca aaagcattga acgagatcac tggctgggag atcggtgcgc
    18181 ctgtttggca tttgatacgc gaaagaaaaa tcaatggcga agtagttata ttagacaccg
    18241 attatctatt aaaggaaatc gttcctattt taactccagc acaagcacaa ggatcgatct
    18301 atgaatattt tgaaaatgag ctttctttga cgattgctta cgcgcaaaag gagatcacag
    18361 tagaagaagt aacggaaatc atgaaaacag cgatggatct tcacgatgac acttatgcag
    18421 tagtagtcag aagcctcgtt catctggaag atacccgctg tttcgagtat tctgagtcgg
    18481 ttcaccgatt agataaattc cgtttcgttg agtttgcccg acgccgaaaa gtgtaaatag
    18541 ttcaaaagaa agcaaattgt tggcatctgt ccactttggc gctatgatag gatcacaaag
    18601 ggggcatttt taatggataa accaataaga ccagaaaaag aagaactgaa agaaaagtta
    18661 tcacccatgg cttatgcagt cacacaagaa aatgcaacag aacgaccatt tagcgggaaa
    18721 tatgatgatt tttacgaaaa ggggatctat gtagatatcg tcagcggtga accgttattc
    18781 agctctgcag aaaaatatga tgcaggttgt ggctggccat cattcagcaa accaataacg
    18841 aaaagacaag tgcgcgaaaa agccgatttt tctcatggca tgcatcgaat agaagttcga
    18901 agcaaagaag cagattctca tctcggacat gtgtttaccg atggaccagt agatcaaggt
    18961 ggtctacgtt actgcatcaa ttctgcctca ctgaaattca ttccatatga aaagatggat
    19021 gaattaggtt atggggtatt caaatcactt gtagaataat ggaaatacac aaagagcggt
    19081 acaatacggg gatttactcg atcgtccgct ctttttttat tcaagcgatt gctatttgaa
    19141 agaaacgctc cctagactcc ttttttcaca aggtgaaatg tgctacaata aagggaacgt
    19201 atgtgtgcaa aagaaagagg actagaatat gtatgaatat ctgacaggtg tggttacctt
    19261 tatcaacccc tattacatag tagtagaaac caatggtatc ggctaccaga tcgcactagg
    19321 aaatccttac cgctacagta gcaaactaaa tcaaaaaata aaaatttatg tccatcaggt
    19381 aatacgtgaa gatgcgcatc ttctgtatgg atttgattcg ctagaagaaa agcaactgtt
    19441 tttgcgatta gtaagtgttt caggaatcgg tccgaaaagt gcccttgcaa tcatggcaag
    19501 cgaagaccac tccggtttga ttcaagcagt agaatccagt gatgtcactt atttgacgaa
    19561 atttccagga gtagggaaaa agacagcaca acaaatgatc ttggatctaa aaggaaaatt
    19621 cggtgagctg agtatcgata caccttttag tctatttgat gaagcaaaca caaaagacgc
    19681 tacagctcta tctgaagcaa tggaagctct ctcggctctt ggttacagtg atcgagaaat
    19741 caaacgtgta gaaaaacaat taaaagaagt agataatcag acaacggatg agtatctacg
    19801 ccaagcactc aagctaatga tgaaaaaata aggaggagac caaatgacag atgaatactt
    19861 gttatcacca gaatctggcg aaaatgaact gagtttggaa aaatctcttc gaccacagct
    19921 gctttctcaa tatatcggac agagaaaagt caaacaagaa cttcagattt acatcgaagc
    19981 tgccagaaat cgggaagaac ctttagatca tgttctgttg tacgggcctc ctggattagg
    20041 aaaaacgacg atggccatgg tcattgctaa tgagatgacc gtaaatattc gtacgacgag
    20101 tggccctgct atcgaacgtc cgggtgactt agtagcaatc ttgaatgaac tggaagcagg
    20161 ggatgtcctg tttatcgatg agatccatcg attacctaga gtggtagaag agatgcttta
    20221 ttcagctatg gaagatttct atgtagatat catggtagga caagggccaa ccgcacatcc
    20281 ggttcatttc cctcttcctc cctttacttt gattggcgcg acgacacggg caggtatgct
    20341 ttctgcacct ttacgagatc gatttggcat catttctcat atggaatatt atgacgaaca
    20401 ggatctgcag gagatcgttt tacgttcttc ggatattttt caaacagaga tcattgaaga
    20461 aggggcattg gaaattgctc gccgatcacg aggaacgcct agaatcgcta atcgcttgct
    20521 caaacgggtt cgtgattttg cgcaagtcca aggagacggg aaaatcgatc gtcctatagc
    20581 ggatcaggca cttactttgc tacaggtcga tcaggctgga ttggattatg ttgaccagaa
    20641 attgttgcga acaatgatcg agttatatgg cggcggacca gtagggttaa gtacgctttc
    20701 agtaaacata ggagaagagc gtgagacggt agaagatatg tatgaaccgt atctgatcca
    20761 aaaaggattt ttaaagcgta cacctagagg gcgaattgct actgcttatg cctatgaaca
    20821 ttttggttac gactatcata tatgattttt gcttttagat tggaggaaaa tgaatgagtg
    20881 atacaacacg tacgaaacaa ttgatcaaaa acgtattgat tgatttgtgc caaacgcaat
    20941 cttttcgaaa aatcagcgtc caaaaaatcg caaacgaagc aaaaatcaat cgacaaacat
    21001 tttattatca ttttacagat aaatacgatt tgcttcgttg ggtctattgt gaggatgcat
    21061 tgcattattt agatccacaa tgtctttcac ttgataattg ggaagagcaa gcattgaaaa
    21121 tgctgaaagc aattgctgag aagaaagaat tttatgcaaa tactgtgctt tctgacccag
    21181 aaattttaca aaaagagttt tctcaactga tccaaaaatc atttatcaag atttttgaac
    21241 aaatggatga agaaagacaa ctttctgcaa gagacaaact attttatgct cgtttttttt
    21301 cttacggttg cagtggtgta ttagtcaatt ggatcacgaa tgaatatgaa gaaacaccga
    21361 tggaaatcgc tatgcagctt ttccgtttag ccaaggatac ggaattatat tcttatcgtc
    21421 tttatgcaaa agaagagttg gaagaacagt aatagaaaaa ttttttgttg gaaaagcaat
    21481 aatcgctaaa aggagatggg gaaatgacaa aaattttatt tgtttgtttg ggaaatattt
    21541 gccgttcacc gatggcagaa ggcttgctga gaaaacgaat agcattagaa ggaagggaag
    21601 cagaattttt tgtggattct gctgctacaa gcacgtatga agttggaaag acaccgcacc
    21661 ctggaacgaa aaaaatatta aaccaagaaa aagtagatat gacgaatatg gttgctcggc
    21721 aaatcacacc ccacgatttt gaaacttttg attggatcat tggcatggat caagaaaatg
    21781 tagaagaact gaaacgaaga gcaccacgct cagcgcaggg gaaaatccat ttgtttttaa
    21841 gtagcattcc tggaaaagaa aaagaaaatg ttcccgaccc atactatacc aataactttg
    21901 atgagacata tcacttgatc acagaaggcc tgaatcattg gtggaatatt tggattgatg
    21961 aaaataaaat aacaaacaat ttgtaaagtt aacgctttct ttttaaggcg atgttagagc
    22021 atttccttgt ttttttgtaa aatgttaggt aaaataaaat taattaagta acactttctt
    22081 agctaaagga ggagtgcatt cgatgaacga agagacagta tcgccaatga agaagcttac
    22141 gaagttagtt actcatactt cgtatcaact ttttgattct tttgtaaatg acactgaaga
    22201 acatgctaag aatgtacgat tgcaaggaaa gtttattctt gagctgcaaa aagctgctac
    22261 tgaacatagt ctagttatct tacaagtaag agcaaatcgt ttgagtagca agtatgaaac
    22321 gatctcaggc tgggtggcga caaaaacggt cgaaaaagac cgagtgatga tccgcctaca
    22381 aaacgaagag cagcagatcc ggatggttcc tgtagaacaa attgaaaaaa taacaatcct
    22441 ttcaccagca ggggaacagg aacggttatc aaaataattt ataccagata gaaaagcacg
    22501 tatgagcttg taccatcaat cattactaat caaaaataac cgaatgcttt aagctgatat
    22561 cagtaaaacg gaacgtttta ggatgagtat catagcatga cagcattcgg ttgattagtt
    22621 gaatcgattg gatggtacaa gtttttttga taaaaaaagg tcctgctagc cggggagcta
    22681 gcaggataag gagttaaaaa tgaaaaagtg ttgttagggt tgtttgttgg tatgcttata
    22741 taatagtcat tagttgtgaa tattttgtga cgaaagtttt cgaaagttgt taagttt
//
LOCUS       DADVXK010000036        22324 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.036, whole genome shotgun sequence.
ACCESSION   DADVXK010000036 DADVXK010000000
VERSION     DADVXK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.036"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            5..403
                     /locus_tag="KB909_001332"
     CDS             5..403
                     /locus_tag="KB909_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6837376.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1081
                     /locus_tag="KB909_001333"
                     /pseudo
     CDS             387..1081
                     /locus_tag="KB909_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(1675..2562)
                     /locus_tag="KB909_001334"
     CDS             complement(1675..2562)
                     /locus_tag="KB909_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6837377.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2747..3586
                     /locus_tag="KB909_001335"
     CDS             2747..3586
                     /locus_tag="KB909_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6837378.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3782..4756
                     /gene="sgrA"
                     /locus_tag="KB909_001336"
     CDS             3782..4756
                     /gene="sgrA"
                     /locus_tag="KB909_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBB6837379.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5054..5410
                     /locus_tag="KB909_001337"
     CDS             5054..5410
                     /locus_tag="KB909_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837380.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5413..6570
                     /locus_tag="KB909_001338"
     CDS             5413..6570
                     /locus_tag="KB909_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837381.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6596..7036)
                     /locus_tag="KB909_001339"
     CDS             complement(6596..7036)
                     /locus_tag="KB909_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6837382.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7196..7702
                     /locus_tag="KB909_001340"
     CDS             7196..7702
                     /locus_tag="KB909_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6837383.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7870..9783
                     /locus_tag="KB909_001341"
     CDS             7870..9783
                     /locus_tag="KB909_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6837384.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9788..10789
                     /locus_tag="KB909_001342"
     CDS             9788..10789
                     /locus_tag="KB909_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6837385.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10991..11197)
                     /locus_tag="KB909_001343"
     CDS             complement(10991..11197)
                     /locus_tag="KB909_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBB6837386.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11843..12691)
                     /locus_tag="KB909_001344"
     CDS             complement(11843..12691)
                     /locus_tag="KB909_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6837387.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12690..13757
                     /gene="gnd"
                     /locus_tag="KB909_001345"
     CDS             12690..13757
                     /gene="gnd"
                     /locus_tag="KB909_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBB6837388.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13759..14760
                     /locus_tag="KB909_001346"
     CDS             13759..14760
                     /locus_tag="KB909_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBB6837389.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14757..15041
                     /locus_tag="KB909_001347"
     CDS             14757..15041
                     /locus_tag="KB909_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBB6837390.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15074..15871
                     /locus_tag="KB909_001348"
     CDS             15074..15871
                     /locus_tag="KB909_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6837391.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15885..16718
                     /locus_tag="KB909_001349"
     CDS             15885..16718
                     /locus_tag="KB909_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837392.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16736..17593
                     /locus_tag="KB909_001350"
     CDS             16736..17593
                     /locus_tag="KB909_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6837393.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17615..18124
                     /locus_tag="KB909_001351"
     CDS             17615..18124
                     /locus_tag="KB909_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837394.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18161..18562
                     /locus_tag="KB909_001352"
     CDS             18161..18562
                     /locus_tag="KB909_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837395.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18674..19027
                     /locus_tag="KB909_001353"
     CDS             18674..19027
                     /locus_tag="KB909_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837396.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19061..19504
                     /locus_tag="KB909_001354"
     CDS             19061..19504
                     /locus_tag="KB909_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6837397.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19521..20606
                     /gene="uxuA"
                     /locus_tag="KB909_001355"
     CDS             19521..20606
                     /gene="uxuA"
                     /locus_tag="KB909_001355"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6837398.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20599..21312
                     /locus_tag="KB909_001356"
     CDS             20599..21312
                     /locus_tag="KB909_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6837399.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21519..21668)
                     /locus_tag="KB909_001357"
     CDS             complement(21519..21668)
                     /locus_tag="KB909_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837400.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22064..22264
                     /locus_tag="KB909_001358"
     CDS             22064..22264
                     /locus_tag="KB909_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6837401.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7689 a         3430 c         4623 g         6582 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcagcgata acgttaggta aagagctact
      961 agatcaagta ttagagatgc cctcgattga taaagcagtg aggggcttcc aagaagattg
     1021 ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa aaggtcgctg attacttctg
     1081 aatcaatttc tccataaaat aaacgatagc cttctcgaaa actcgaggag gctatctgac
     1141 gattcaatat tcattaattt aaagtttggg tgactattac taactattac ttatttctca
     1201 tttaaacgat gtattcccta acctctaata catccttgta actctgaagt tacgccagtt
     1261 ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt tcgtgtttct
     1321 ctagtataac agaataagaa gaacaagtcc agaagggata tttttagtct tttttaaaat
     1381 aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg gcaagtgaaa
     1441 aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga tagaaataaa
     1501 aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt tttggtacaa
     1561 ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa taagaaggaa
     1621 tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat ttgtttattt
     1681 gaatatattt tttacataag gatctttaat agttacattg tcttttttca tcactttacg
     1741 gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa ttttttctag
     1801 ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca tttttactag
     1861 ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag aaacttcccc
     1921 gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat tggttgaatc
     1981 aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag cttgaacaag
     2041 cttggagaaa ttttctcctt catttgcttc tttttttgct ttatctgctt cttctttagt
     2101 cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag cagtgtctag
     2161 atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca gcatctgttt
     2221 aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt ccttgtagtt
     2281 tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg aagaaatctc
     2341 ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata gtgtttgatt
     2401 atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc cacctttaaa
     2461 cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg cacatgctga
     2521 aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct tattaaaaac
     2581 agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct gtagatattc
     2641 ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt ttcacgagac
     2701 aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga tcaggattat
     2761 tcggttgatt ggatctgttt taatagtctt tgttggtttt gttttaggaa ttcttgtcaa
     2821 taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa ttgccggtac
     2881 ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg tcgaaggaaa
     2941 aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt tagcgggagg
     3001 tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt tgacgggggc
     3061 gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt ttattttatt
     3121 tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc atcagatgct
     3181 tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc ttttgcacgg
     3241 attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag gttgcttttt
     3301 cagcgcactt atctacagta caggaagttt atttacggct attggtgctc atattacttg
     3361 gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag aacaaggttt
     3421 tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact ttggggctga
     3481 agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt tactctatgc
     3541 atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga tgaagaaagc
     3601 aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa aagtaaacaa
     3661 attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc gtgttctcat
     3721 cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga gagtgataga
     3781 aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa ttgcagcaat
     3841 gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat ttactgtgaa
     3901 aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag tcaaaccaaa
     3961 caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg atggtaatgg
     4021 aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga ccgctggtat
     4081 tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga gtaaagataa
     4141 agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt tgaaaccaag
     4201 cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg aaagcagtac
     4261 agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaatta gcacagaaaa
     4321 cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag gaagcacgag
     4381 cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca tgagtagtga
     4441 gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata atgaacttga
     4501 tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca acctaaaaag
     4561 tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa aagcgaaaga
     4621 aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga acaagctaat
     4681 tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc gttctctctt
     4741 ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa cgatagattt
     4801 ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag ctttgccaga
     4861 tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac aaatggaaaa
     4921 taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga aaaatcagta
     4981 acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata atagataaaa
     5041 aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag tatatcaatt
     5101 tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata tcgctttaga
     5161 tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat cgttttgcga
     5221 aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa aagtcgagtt
     5281 ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa cgattggtta
     5341 tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc ttagtcaaaa
     5401 aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac tattttgaaa
     5461 aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga agaataccgt
     5521 atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca ttctgatata
     5581 ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca tgcgccatat
     5641 acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt gcaacgaatg
     5701 aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt gcatccattg
     5761 ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc aaacttctgg
     5821 tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt tggtgtaatg
     5881 aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga aagttggggc
     5941 tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg ttttacaact
     6001 tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc aagggttttt
     6061 gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga ttttcagcat
     6121 atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc tcgcagaatt
     6181 ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata ctgtatgtta
     6241 gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca atcaaagtat
     6301 ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga acgcccaata
     6361 aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta tcctatcgac
     6421 aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca acctacaaaa
     6481 aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa aaatagatcc
     6541 atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc caaaattaag
     6601 acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc aagagttcgt
     6661 tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct tcgctaaatc
     6721 cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa gaaggggatg
     6781 tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga acaagatttt
     6841 tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc aattttagta
     6901 agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg ataaacggta
     6961 tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca gaacctgtat
     7021 acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa taacatgaag
     7081 aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca cgtataatgg
     7141 aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca caagtatgtc
     7201 aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt ttgattcttc
     7261 gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca aaacatacga
     7321 aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag tgccacaaac
     7381 aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt ttgtgagaaa
     7441 aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg aattggactg
     7501 tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga ctgtgaagtt
     7561 tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa cttatgataa
     7621 tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg ataaacgatt
     7681 tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa tggatactgg
     7741 tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat ttttatggga
     7801 taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct cctagaaaca
     7861 taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt ggtcatctta
     7921 tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat ttcttccgaa
     7981 tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga aacgaaatcg
     8041 agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt tactagcaca
     8101 gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac agctacaaaa
     8161 atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg gacagaaaat
     8221 gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta cttcggtaaa
     8281 cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt aatagagtta
     8341 ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat caaacatctg
     8401 attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt gatgtcgatg
     8461 cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta tccaaataca
     8521 aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga tgtatatgca
     8581 tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt tcgagggaat
     8641 tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg gtataattta
     8701 ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac ctatggacaa
     8761 tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg gccatctcaa
     8821 aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt attagcgaaa
     8881 gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc aattgatgaa
     8941 caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc cataaaaaat
     9001 cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct tttgaaacaa
     9061 tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac gattggaatg
     9121 tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt acctgtgtct
     9181 aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt agtagaagga
     9241 gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca tgtaacggac
     9301 tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga aaacaataaa
     9361 agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga aaattatatg
     9421 acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc gactgaaggg
     9481 atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc agtagctcca
     9541 ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga acctcgagag
     9601 gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca aaaaaagaca
     9661 gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct tctcatttat
     9721 tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag aaagagaggg
     9781 taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca tcgtagttat
     9841 tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct tgcttgttag
     9901 aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg atttccagca
     9961 aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt acaaaaataa
    10021 taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc ttttctggat
    10081 gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt tggaatatct
    10141 atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac cggaagcaaa
    10201 acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa aagagataaa
    10261 agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg cacaaattag
    10321 tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc atcttgatcc
    10381 gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt tggatccttc
    10441 tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat gtggatgggc
    10501 ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag ccttggtcag
    10561 acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa atacgtttac
    10621 gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag tcacaaaagt
    10681 agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt tcagcaataa
    10741 acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa gtcttatgat
    10801 gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt tcaataaaca
    10861 agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga tggcaagggg
    10921 caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc ttttacgtaa
    10981 attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat ccgaagcctg
    11041 cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt tccactaata
    11101 ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa atcaatgcac
    11161 tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc ttttttataa
    11221 ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga tgtgaataaa
    11281 atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa tgattcagca
    11341 atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa atatgggaat
    11401 ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg atgtatccta
    11461 aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca aatgataacc
    11521 taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa aatttttttt
    11581 aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa ttttttacta
    11641 ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca atacaacctt
    11701 ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct gtaccaccct
    11761 tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt tttatggatt
    11821 tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt cgaactttag
    11881 cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat agagagtcca
    11941 aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct gtttcttcag
    12001 aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct tggctagtaa
    12061 taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt gtttcttttg
    12121 attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa gaagcttcca
    12181 tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc aaaaatttat
    12241 gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag acacgtttag
    12301 attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac ttttttgtgt
    12361 catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc tcagtatctg
    12421 ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg atcaacatgg
    12481 ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga aaaaaagtag
    12541 agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt actttgcttg
    12601 gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg ttgtacattg
    12661 ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat aataagatta
    12721 tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa aatcaaacaa
    12781 aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa
    12841 atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag
    12901 ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg
    12961 ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta
    13021 cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca
    13081 tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa ggcggaaact
    13141 cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact
    13201 tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg
    13261 gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa
    13321 gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg
    13381 gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg
    13441 agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg
    13501 gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc
    13561 ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg
    13621 ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag
    13681 atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag
    13741 ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc
    13801 ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt
    13861 actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc
    13921 attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg
    13981 ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa
    14041 caccagacaa tcgtatctat catacctgct ttaattgaac gaaatgctgt agcagaaaat
    14101 aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag
    14161 gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt
    14221 ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt
    14281 cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt
    14341 gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg
    14401 aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa
    14461 aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat
    14521 ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga
    14581 cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc
    14641 tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc
    14701 agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga
    14761 tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag
    14821 aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg
    14881 tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg
    14941 aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac
    15001 gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa
    15061 actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc
    15121 tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg
    15181 acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc
    15241 ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag atacactagc
    15301 aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt
    15361 gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa
    15421 agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat
    15481 tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc
    15541 agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca
    15601 tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa
    15661 aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat
    15721 gggattattt ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa
    15781 agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat
    15841 ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg
    15901 tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg
    15961 gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga
    16021 tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg
    16081 gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag
    16141 taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag
    16201 tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta
    16261 aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc
    16321 tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt
    16381 taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca
    16441 ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta
    16501 tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga
    16561 aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct
    16621 ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat
    16681 cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc
    16741 tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa
    16801 agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc
    16861 gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc
    16921 tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg
    16981 cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga
    17041 agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg
    17101 ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc
    17161 aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg
    17221 ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg
    17281 ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc
    17341 agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc
    17401 attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt
    17461 gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg
    17521 attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat
    17581 cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt
    17641 ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa
    17701 ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa
    17761 aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt
    17821 ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca
    17881 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
    17941 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
    18001 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
    18061 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
    18121 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
    18181 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
    18241 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
    18301 cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa
    18361 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
    18421 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
    18481 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
    18541 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
    18601 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
    18661 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
    18721 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
    18781 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
    18841 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
    18901 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
    18961 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
    19021 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
    19081 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
    19141 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
    19201 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
    19261 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
    19321 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
    19381 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
    19441 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
    19501 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
    19561 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
    19621 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
    19681 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
    19741 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
    19801 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
    19861 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
    19921 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
    19981 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
    20041 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
    20101 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
    20161 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
    20221 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
    20281 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
    20341 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
    20401 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
    20461 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
    20521 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
    20581 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
    20641 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
    20701 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
    20761 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
    20821 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
    20881 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
    20941 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
    21001 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
    21061 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
    21121 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
    21181 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
    21241 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
    21301 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
    21361 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
    21421 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
    21481 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
    21541 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
    21601 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
    21661 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
    21721 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
    21781 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
    21841 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
    21901 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
    21961 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
    22021 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
    22081 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
    22141 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
    22201 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
    22261 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
    22321 aaat
//
LOCUS       DADVXK010000037        21927 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.037, whole genome shotgun sequence.
ACCESSION   DADVXK010000037 DADVXK010000000
VERSION     DADVXK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.037"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            278..1063
                     /locus_tag="KB909_001359"
     CDS             278..1063
                     /locus_tag="KB909_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6837402.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1076..1927
                     /locus_tag="KB909_001360"
     CDS             1076..1927
                     /locus_tag="KB909_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBB6837403.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2051..2503)
                     /locus_tag="KB909_001361"
     CDS             complement(2051..2503)
                     /locus_tag="KB909_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837404.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2968..3336)
                     /locus_tag="KB909_001362"
     CDS             complement(2968..3336)
                     /locus_tag="KB909_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBB6837405.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3486..3968
                     /locus_tag="KB909_001363"
     CDS             3486..3968
                     /locus_tag="KB909_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBB6837406.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4005..5015
                     /locus_tag="KB909_001364"
     CDS             4005..5015
                     /locus_tag="KB909_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBB6837407.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5130..5843)
                     /locus_tag="KB909_001365"
     CDS             complement(5130..5843)
                     /locus_tag="KB909_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837408.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6033..6623)
                     /locus_tag="KB909_001366"
     CDS             complement(6033..6623)
                     /locus_tag="KB909_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBB6837409.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7107..7334
                     /locus_tag="KB909_001367"
     CDS             7107..7334
                     /locus_tag="KB909_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBB6837410.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7350..8516
                     /locus_tag="KB909_001368"
     CDS             7350..8516
                     /locus_tag="KB909_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBB6837411.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8750..9793
                     /gene="hrcA"
                     /locus_tag="KB909_001369"
     CDS             8750..9793
                     /gene="hrcA"
                     /locus_tag="KB909_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBB6837412.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9887..10450
                     /gene="grpE"
                     /locus_tag="KB909_001370"
     CDS             9887..10450
                     /gene="grpE"
                     /locus_tag="KB909_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBB6837413.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10501..12330
                     /gene="dnaK"
                     /locus_tag="KB909_001371"
     CDS             10501..12330
                     /gene="dnaK"
                     /locus_tag="KB909_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBB6837414.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12481..13647
                     /gene="dnaJ"
                     /locus_tag="KB909_001372"
     CDS             12481..13647
                     /gene="dnaJ"
                     /locus_tag="KB909_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBB6837415.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13729..14394)
                     /locus_tag="KB909_001373"
     CDS             complement(13729..14394)
                     /locus_tag="KB909_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837416.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            14370..14543
                     /locus_tag="KB909_001374"
     CDS             14370..14543
                     /locus_tag="KB909_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837417.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14588..15325)
                     /locus_tag="KB909_001375"
     CDS             complement(14588..15325)
                     /locus_tag="KB909_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6837418.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15327..16829)
                     /locus_tag="KB909_001376"
     CDS             complement(15327..16829)
                     /locus_tag="KB909_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBB6837419.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17088..19082
                     /gene="uvrB"
                     /locus_tag="KB909_001377"
     CDS             17088..19082
                     /gene="uvrB"
                     /locus_tag="KB909_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBB6837420.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19092..21908
                     /gene="uvrA"
                     /locus_tag="KB909_001378"
     CDS             19092..21908
                     /gene="uvrA"
                     /locus_tag="KB909_001378"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBB6837421.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
BASE COUNT         7184 a         3792 c         4660 g         6291 t
ORIGIN      
        1 aaggggctgt gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa
       61 gtagcttctt cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct
      121 ttctttatag aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat
      181 ttgctttaga ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg
      241 taataacagg tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa
      301 agtcgcagta gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg
      361 gaaagaaaaa atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc
      421 agtcaaagca atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc
      481 tgaagaagga atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt
      541 ttgggttaat aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga
      601 ttgggaaaga gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt
      661 aaattacttt acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga
      721 acagatccca tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt
      781 taccgaaacg gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc
      841 tggtgctatc cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact
      901 cttggaaagt atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc
      961 tgcatggttg gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg
     1021 tgggatgact ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg
     1081 tttattgatt gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa
     1141 gattggtggc agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg
     1201 cttactcgtt caattattcg cttctccagc tggtatttca gtgactacat ttttgattag
     1261 tttactttct ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt
     1321 gattggtgtt tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt
     1381 gattggtgtc ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc
     1441 agcaatcatt cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa
     1501 aaaaggcggt atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt
     1561 atacagtgca ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat
     1621 gatcggtgtc tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc
     1681 tgaagacaag agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc
     1741 ttatattttt tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa
     1801 cgtagttatc tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga
     1861 aaaaaaatta acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt
     1921 tatttgagga taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac
     1981 agtaagtact tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct
     2041 ttttaattgt ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc
     2101 attgactaaa gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt
     2161 ctttataaag atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt
     2221 actggactaa ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga
     2281 aacgcatcgt gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg
     2341 cttgatctcc gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa
     2401 cctttgttcc ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac
     2461 ctaattgttc ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt
     2521 gaatggttct actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt
     2581 taattaaggt cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa
     2641 ttcgttctct cctaaagtga tattatattt aaatatacct gaaaataatg ggcagtatta
     2701 tgaaagatca ctgatatttt ctcgtatttt ttccttattc aaaagttttg caggaaaatt
     2761 gctgaaaaaa taattttact aagtagaaaa ttcaaagcca ttcaatcagt gatttttttc
     2821 agcacaagaa agactcctta taaaaatagc agatactttg tcaattaagt gtttaaccag
     2881 ggatgataaa aaggatagga ttgaacaaaa cctgtataag gtgatgaata gtttcctcgc
     2941 cagtaaaagg tttattcgta taaagcttta tcgccaaaat ttatcatgac cttttttatc
     3001 ttcaatatta aatgaaatca attgttcaat caattcccag ttgattacac ttttccaagg
     3061 aactttgatg acgttatccg tatatacgta gcctgcttct tggatatttt tttcaagggc
     3121 acgaatcgct gctttttccg gtgcgataga aaaatgattt ttagcaaaac taaatgcaat
     3181 aataaaggta ccatggtcag taaacatagg ttggttccat tttacagttg tgtctagctg
     3241 gggatacgtt tctgttatct tagcaaaaag gtctttgatc ttttgttgat gttctttttc
     3301 tttgatttga ttgatgatcg gctgaaattt ttccattcta aaacgcctcc attaagtggt
     3361 ttgatttatt ttaccagaaa aacaatagtt atgtataaaa aacgaacaaa acacaagtaa
     3421 tgttgtaacc gctatattta tatgataaga tgtctcaaat aataaaatag aaaagagaca
     3481 taaaaatgat tgacttggca aagaaattct tacacgaaaa tatatatttt gagttgtatc
     3541 atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa caaggattta
     3601 caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac tacgtatatc
     3661 tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc ggtaaaaggc
     3721 tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag ggcgctgttt
     3781 ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc ttatcaaatg
     3841 aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa acggttgact
     3901 taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca aacgaaaaaa
     3961 acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata agttatccat
     4021 tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta tcagaggaac
     4081 accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc caagtagtta
     4141 ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga aaacgagcag
     4201 atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg acttggggag
     4261 gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa ccaaaatgga
     4321 tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa acagggatag
     4381 ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat gaaacgacag
     4441 caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag caatcttctg
     4501 aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc catctcactg
     4561 aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga cgattattag
     4621 gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat gtccaatctt
     4681 ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac tgtgagctat
     4741 cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg tttgatggca
     4801 gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat aaaatgaagg
     4861 atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat attgattgtg
     4921 gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta gcggtagaag
     4981 atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc cttggagtct
     5041 atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa aatgctgtca
     5101 gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac atcgattaac
     5161 tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt atcaatgatt
     5221 tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg catttgccaa
     5281 tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata cactaaaact
     5341 ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac tgcactccct
     5401 gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa ttcgaaatca
     5461 cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc gtactcaatt
     5521 tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga ggaggttgtg
     5581 tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga agaagtattg
     5641 ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc tgatttctga
     5701 gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt ggtcgcagat
     5761 ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga gaccaacaat
     5821 aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata ccagtatagc
     5881 ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag agtgtatctt
     5941 ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac ttgtcacact
     6001 attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc gtacttttta
     6061 tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat ttcttctgtt
     6121 tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt tccattcgca
     6181 gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt attctgataa
     6241 ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc ttgcaataat
     6301 ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac gtctgttttt
     6361 aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga attgccaccg
     6421 atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc gatttttgtt
     6481 tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt ttgccatttc
     6541 tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata ttcctctaat
     6601 agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa caaggacaac
     6661 agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca acaattctta
     6721 agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa taaaaatgac
     6781 aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg acaaaagaac
     6841 caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa gtaattatag
     6901 aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga gatatataac
     6961 taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg gattttttag
     7021 tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag caaagcgttg
     7081 tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt gcagattttg
     7141 acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta aaagcaccgt
     7201 gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat tctaaatatg
     7261 cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg
     7321 acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc gcagaaaaca
     7381 aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac tgtgatttta
     7441 ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa
     7501 tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac gtagggggcg
     7561 ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt gctagagaga
     7621 tcctgccttt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt gatttgaccc
     7681 gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga
     7741 catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa gatgtgtatc
     7801 aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg
     7861 cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct ttggctttgg
     7921 atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg ttcatgaact
     7981 gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga atgtttgaag
     8041 agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt aactttgggc
     8101 tctccggaca tgaatctcaa cataacctca tgtactggaa caatgcccac tattttgggt
     8161 ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa ggaccaatcc
     8221 aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa gaaaaattga
     8281 cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa acagggatta
     8341 ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc
     8401 taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt tatttgacac
     8461 caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa aaatagttta
     8521 aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac aataaaggac
     8581 tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca ctcttgtgtt
     8641 tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg ctatatttat
     8701 aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga tgttaacaaa
     8761 gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg gcgtgcccgt
     8821 tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga ttcgcaatga
     8881 tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt ctgggcggat
     8941 tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg ctcgcgtagc
     9001 agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg aaatcaatga
     9061 gattattaag caatctgctg agatattatc tgagctgaca agctatacga ctttttcatt
     9121 gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct tgaataatcg
     9181 acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag tgttcactct
     9241 tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa acgaccgtct
     9301 agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc cgatgattct
     9361 tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg ttcttggtca
     9421 tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt atgagccccg
     9481 tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag acggacttac
     9541 acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg aattaggcaa
     9601 tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg gtcatggaag
     9661 aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt tcggtctagt
     9721 cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt cgcttgactt
     9781 gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct ctttcttagt
     9841 aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga aagaaaatca
     9901 agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg atgtcgaagc
     9961 tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag cgaaattaaa
    10021 agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa tcgcaaatat
    10081 ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac aagatttagc
    10141 caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag aagtgtcaga
    10201 tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt tgcgtaacgc
    10261 actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg atcctaatct
    10321 tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata cgattgtaga
    10381 agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca tggtcattgt
    10441 tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga gacgttaatt
    10501 atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc agtattggaa
    10561 ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc ttctgttgta
    10621 tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc tgtgacaaac
    10681 ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa agtagatgta
    10741 gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata tatcaaagga
    10801 ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt gccagcttac
    10861 tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg tctagaagta
    10921 gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga taaaacagat
    10981 cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt atctatcctt
    11041 gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca tctaggtggg
    11101 gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa agaaaacagc
    11161 attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc tgaaaaagcg
    11221 aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat cacagcagga
    11281 gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga tgaattaaca
    11341 gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga tgcaggttta
    11401 tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat ccctgcagtt
    11461 gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa ccctgatgaa
    11521 gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt gaaagatgtt
    11581 gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg agtgttcact
    11641 aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt ctcaactgcg
    11701 gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc aatggctgct
    11761 gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc tcgtggtatt
    11821 ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt atctgcgaaa
    11881 gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg tctaacagac
    11941 gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga taaagctcgt
    12001 aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt ggacaaaaca
    12061 ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga aacagctcgc
    12121 gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac taaacgcgat
    12181 gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc ggcacaacaa
    12241 caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt tgatgctgat
    12301 tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag agaaggccaa
    12361 agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt ttgtttcaaa
    12421 caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg aggaaagcct
    12481 atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc atcagaagat
    12541 gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat caataaagaa
    12601 cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt aagtgacccg
    12661 caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa ttacggtgct
    12721 ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg cttcggtggt
    12781 tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga tccaaatgcg
    12841 cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga agcgattttt
    12901 ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg tggtgggaac
    12961 ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc aggtacgatt
    13021 aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg tgatgtttgt
    13081 catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc aggacatgag
    13141 aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg acaacaaatg
    13201 cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga tttgtatgtg
    13261 gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat ttactatgaa
    13321 ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc aactgtccat
    13381 ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt ccgtttacgt
    13441 ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt caaagtaaaa
    13501 ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc attcgctgaa
    13561 gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa gtttaaagat
    13621 gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt cattaataat
    13681 taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc atgtttgtac
    13741 caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg tataaccagt
    13801 gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa ataattcttc
    13861 tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct tcttgaacaa
    13921 atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg ttcgttgatc
    13981 tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc ggatctcgtt
    14041 cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga aagattgcgg
    14101 tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta actgatacat
    14161 tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc tggaaatccg
    14221 attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc cgtaataaga
    14281 gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca attgctgatt
    14341 gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct caattaagtg
    14401 agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt tcttatgcga
    14461 tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg ctgatacgat
    14521 taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg tgcatttttg
    14581 gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca ttttgcggat
    14641 tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca atgaacatga
    14701 cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc atcgtcatac
    14761 cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca ggatcgagtg
    14821 cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca cgagcaatag
    14881 ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt ttatcttcta
    14941 gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta gattctttct
    15001 tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg aataggttaa
    15061 agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg cttttatcca
    15121 tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa cgattcaagc
    15181 aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg acatctcctt
    15241 cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt ttgactaaat
    15301 gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac ttttgctaat
    15361 tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta aacatacgta
    15421 ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac tacaccgatt
    15481 gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa tgatgggatc
    15541 atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata agaaagacct
    15601 aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc tcgaacaatc
    15661 tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag gaagtcagga
    15721 atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag aaccatcatt
    15781 ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc gcgtattggt
    15841 gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa ggagatcaaa
    15901 gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt ttggataagt
    15961 ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga accatccgct
    16021 acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt caatccttca
    16081 ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc atattttccg
    16141 ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc ataaccgatt
    16201 accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc gtacaattga
    16261 tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc gcttaaaaat
    16321 tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc ttcataagac
    16381 ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa gtaagaatca
    16441 gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat cattccgtct
    16501 gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc cattcggatg
    16561 ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc ttcgtactcg
    16621 ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat tacgtatacg
    16681 tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc cgttgtagtg
    16741 ttgtcagctt gtgcaacatg accaaacgca agtgtcacaa gtcctgtcat taagaaaaca
    16801 aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca atattttatt
    16861 attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat gaaaaaaatg
    16921 cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa aaaagtggcg
    16981 aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt ccttttcttt
    17041 ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg attgagagag
    17101 atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat cagcctgaag
    17161 cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc ttattaggtg
    17221 cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg aataaaccaa
    17281 cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa ttcaaggaat
    17341 ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat cagcctgaag
    17401 cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat gatgagatcg
    17461 acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg atcgtcattg
    17521 catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa caagtagttt
    17581 cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta gtcagtatcc
    17641 aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc ggtgatgtcg
    17701 tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt tttggagatg
    17761 aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga gaaacggaac
    17821 acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg gagcatgccg
    17881 tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat gaaaacaaac
    17941 ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg atgttagaaa
    18001 tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt aaagaaggtg
    18061 aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg gcggacgaat
    18121 cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg agaaaacaga
    18181 tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca cttcggttag
    18241 aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca ggaccatatg
    18301 aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg ctgcttgacc
    18361 cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc gaaataaatg
    18421 aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa atggcagaag
    18481 acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat agtgatatca
    18541 aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt gatgtgttag
    18601 ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt gttgctatct
    18661 tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa acgattggac
    18721 gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta acagattcta
    18781 tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag tacaatgaag
    18841 aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt tctattacga
    18901 aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa atgacgaagg
    18961 aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg gcaaaagctt
    19021 tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa gcttcaaagt
    19081 aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc cataacttga
    19141 aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt ttgtccggtt
    19201 ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg agatacgtag
    19261 agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg gacgtagata
    19321 gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt aaaaatcctc
    19381 ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg tttgcacgtg
    19441 taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca gtagatcaaa
    19501 tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg gcaccgatcg
    19561 tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa gagggatacg
    19621 tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag ctggagaaaa
    19681 acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa gggattcgtt
    19741 ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat gctctggttg
    19801 acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct tattgcggat
    19861 ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt ggagcttgtc
    19921 cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg attccagata
    19981 gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc tctcagtatt
    20041 atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat acaccattcg
    20101 aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat cttttccatt
    20161 tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc gaaggggtat
    20221 tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt gagcaaatgc
    20281 gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg aatccccaag
    20341 ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg tctattcaaa
    20401 aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta attgccaaac
    20461 cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga ctagactatc
    20521 taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga atcagattgg
    20581 ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa ccatcgatcg
    20641 gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg cgtgatcttg
    20701 gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca gattatttga
    20761 ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca ggcactcctg
    20821 aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg aaaaaatcaa
    20881 tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc actggtgctt
    20941 cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt gtagcagtca
    21001 caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag aaatcgttag
    21061 cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt tccggctacg
    21121 aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg ccgagaagta
    21181 atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct caaacgaacg
    21241 aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa ggcggtcgtt
    21301 gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg cctgatgtct
    21361 atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta gaagtgcatt
    21421 acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct gtagaattct
    21481 tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt ggcttaggtt
    21541 atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa cggatgaaac
    21601 ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta gatgaaccaa
    21661 cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa agattagtag
    21721 atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa acagcagatt
    21781 atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt gcgactggaa
    21841 caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg aaaaaaataa
    21901 tggtataaag aggatagata gctgaga
//
LOCUS       DADVXK010000038        21813 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.038, whole genome shotgun sequence.
ACCESSION   DADVXK010000038 DADVXK010000000
VERSION     DADVXK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.038"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="KB909_001379"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="KB909_001379"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBB6837422.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="KB909_001380"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="KB909_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBB6837423.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="KB909_001381"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="KB909_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBB6837424.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="KB909_001382"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="KB909_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBB6837425.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="KB909_001383"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="KB909_001383"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBB6837426.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="KB909_001384"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="KB909_001384"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBB6837427.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="KB909_001385"
     CDS             complement(8557..9027)
                     /locus_tag="KB909_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBB6837428.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="KB909_001386"
     CDS             complement(9073..9498)
                     /locus_tag="KB909_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBB6837429.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="KB909_001387"
     CDS             complement(9565..9834)
                     /locus_tag="KB909_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBB6837430.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="KB909_001388"
     CDS             complement(9845..11440)
                     /locus_tag="KB909_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6837431.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="KB909_001389"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="KB909_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBB6837432.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /locus_tag="KB909_001390"
     CDS             complement(14993..15553)
                     /locus_tag="KB909_001390"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBB6837433.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="KB909_001391"
     CDS             15906..16880
                     /locus_tag="KB909_001391"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6837434.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="KB909_001392"
     CDS             17050..18450
                     /locus_tag="KB909_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBB6837435.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="KB909_001393"
     CDS             complement(18528..19250)
                     /locus_tag="KB909_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6837436.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="KB909_001394"
     CDS             complement(19329..19835)
                     /locus_tag="KB909_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6837437.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="KB909_001395"
     CDS             19958..21757
                     /locus_tag="KB909_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBB6837438.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         6053 a         4752 c         3911 g         7097 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ttgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttg
//
LOCUS       DADVXK010000039        21496 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.039, whole genome shotgun sequence.
ACCESSION   DADVXK010000039 DADVXK010000000
VERSION     DADVXK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.039"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            177..878
                     /locus_tag="KB909_001396"
     CDS             177..878
                     /locus_tag="KB909_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6837439.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1487..2503)
                     /gene="tsaD"
                     /locus_tag="KB909_001397"
     CDS             complement(1487..2503)
                     /gene="tsaD"
                     /locus_tag="KB909_001397"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBB6837440.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2500..2964)
                     /gene="rimI"
                     /locus_tag="KB909_001398"
     CDS             complement(2500..2964)
                     /gene="rimI"
                     /locus_tag="KB909_001398"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6837441.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2971..3513)
                     /gene="rimI"
                     /locus_tag="KB909_001399"
     CDS             complement(2971..3513)
                     /gene="rimI"
                     /locus_tag="KB909_001399"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6837442.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3497..4219)
                     /gene="tsaB"
                     /locus_tag="KB909_001400"
     CDS             complement(3497..4219)
                     /gene="tsaB"
                     /locus_tag="KB909_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBB6837443.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4410..5390)
                     /locus_tag="KB909_001401"
     CDS             complement(4410..5390)
                     /locus_tag="KB909_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6837444.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5414..6898)
                     /gene="galT"
                     /locus_tag="KB909_001402"
     CDS             complement(5414..6898)
                     /gene="galT"
                     /locus_tag="KB909_001402"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBB6837445.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6910..7899)
                     /gene="galE"
                     /locus_tag="KB909_001403"
     CDS             complement(6910..7899)
                     /gene="galE"
                     /locus_tag="KB909_001403"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBB6837446.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8147..8314
                     /locus_tag="KB909_001404"
     CDS             8147..8314
                     /locus_tag="KB909_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBB6837447.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8376..10187)
                     /locus_tag="KB909_001405"
     CDS             complement(8376..10187)
                     /locus_tag="KB909_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBB6837448.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10184..10549)
                     /locus_tag="KB909_001406"
     CDS             complement(10184..10549)
                     /locus_tag="KB909_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBB6837449.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10712..11107)
                     /locus_tag="KB909_001407"
     CDS             complement(10712..11107)
                     /locus_tag="KB909_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6837450.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11125..12087)
                     /locus_tag="KB909_001408"
     CDS             complement(11125..12087)
                     /locus_tag="KB909_001408"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBB6837451.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12087..12299)
                     /locus_tag="KB909_001409"
     CDS             complement(12087..12299)
                     /locus_tag="KB909_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBB6837452.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12320..13018)
                     /locus_tag="KB909_001410"
     CDS             complement(12320..13018)
                     /locus_tag="KB909_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBB6837453.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(13038..13580)
                     /locus_tag="KB909_001411"
     CDS             complement(13038..13580)
                     /locus_tag="KB909_001411"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBB6837454.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13712..14716)
                     /locus_tag="KB909_001412"
     CDS             complement(13712..14716)
                     /locus_tag="KB909_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6837455.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14713..15702)
                     /locus_tag="KB909_001413"
     CDS             complement(14713..15702)
                     /locus_tag="KB909_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6837456.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15699..16505)
                     /locus_tag="KB909_001414"
     CDS             complement(15699..16505)
                     /locus_tag="KB909_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837457.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16671..17627
                     /locus_tag="KB909_001415"
     CDS             16671..17627
                     /locus_tag="KB909_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6837458.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17704..18222)
                     /locus_tag="KB909_001416"
     CDS             complement(17704..18222)
                     /locus_tag="KB909_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6837459.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18310..18459)
                     /gene="rpmG"
                     /locus_tag="KB909_001417"
     CDS             complement(18310..18459)
                     /gene="rpmG"
                     /locus_tag="KB909_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6837460.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18687..19133
                     /locus_tag="KB909_001418"
     CDS             18687..19133
                     /locus_tag="KB909_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6837461.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19328..21223)
                     /gene="asnB"
                     /locus_tag="KB909_001419"
     CDS             complement(19328..21223)
                     /gene="asnB"
                     /locus_tag="KB909_001419"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBB6837462.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6473 a         4560 c         3701 g         6762 t
ORIGIN      
        1 cacaaatcat tcgcttcaaa acaaattatt caataccatt gtatattttt tacataataa
       61 caaattatat ttgtaaagta ttaaaacttg tttctaatgt tggtatgtta aaactttaca
      121 aattctttaa aaaaagtgac aataaatata gtgaacaata aggagaggac tttttaatgc
      181 gtgttaataa aatcgatttt cacttttcaa aactcagata tcaacctgat tttgaacatt
      241 tctcggatga agagttccaa cagatcaagg aacatactgt tcttcgttct tataaaaaag
      301 gacagatcct tttcgacgat ggtgatccca gacaacggtt gtatatcttg accaaaggac
      361 tcgttcgttt agaacgttat gatgaaagtg caacttatta ctactatgac tatgtgaata
      421 caaataacct ttttcctatg tcaggaatgt ttggagaaga gacctacact tatacagctc
      481 aagcgatgac tgatattgaa acattctacc ttcctgtttc ctactatgaa aaattagcac
      541 gaaaaaatcc cgaacagttg atctatatga tacaaaaaat ttctaaagta gttgaaatac
      601 atgaattgcg tatccaaatc ggattgacct ctagcgcctt tgaccgggta aaacaaaatt
      661 tattcatttt gaaagaagaa ttgggcgtac caacaaaaga tggtcatatc accattcctt
      721 atccgatcac cttaaaagaa ttagcagtga atagcggcac gacacgtgaa actgctggac
      781 aagtaatcaa acaactacgt gattccgggc tgttagatta tgacaaaaag cgttttactt
      841 tctgtaagac agctactact ccagctatga gagaataacg cgaacaaaaa taagcagtga
      901 ccctgataaa tatcagggtc actgcttatt ttcctcccta aaacttctga aagatccggc
      961 agttttagat cactggacaa gactcaaaga ttttctatgt gtgtttcagt tatgtaatat
     1021 tcactgtttg caaaaaatac tgttagatta actagatgaa gcgtcttgtc ctcatccgat
     1081 ctagattatt cgatattcct cgacaataaa cgattactca gtgagggcaa tcagaggaac
     1141 ggataatgat aaataagctg taaaaaatag caaaataaca ataatgatta aaagtatgta
     1201 aaaaataggg ctttgacaaa aacgtgtcac agccctattt cgattaaacg gtgtgtacct
     1261 gtcaactctt cggtcacaag tcataatgtt cataaacatg aggagctgtt ttttgaaatt
     1321 gttccttgtg aatcagagtt aaacgacagg cttacgaact cttgattaaa cggcgttcaa
     1381 aagcttgcat acgcggtaat aagaacagcc aggtcaaaaa catgagaagc cgtttttcct
     1441 gggctgttct tattacttga tgcagggcag ctttttcaca acctctttat tcagataaaa
     1501 ccaagcttgg atcagcattc aactgatagc tagcaaaatt tcttttttgc atttccacat
     1561 gtgctgctgc tccaatcatt gcagcattat ctccacaaag tcgaagaggg ggaatcacta
     1621 gttctacctc agggagttta gctgccaaag catcctgcaa tccttcacgc aacccttgat
     1681 tggccgctac acctccagct ataatcagtt gcttgactgg ataattttga caagctcgaa
     1741 gtgttttagt aatcaataca tcgatcacac ttgcttgaaa gctagctgct aaatcatttt
     1801 tgtctagatc ttctccacgc tgttgtgcat tatgcaccaa attgataaat gcacttttta
     1861 atccgctaaa actgaaatca taattatctt catggatcat cgctcgcgga aaatggtaat
     1921 tatcttttcc ctgatgagct agctgatcga tttcttttcc gcttgggtaa gaaagaccta
     1981 atactcttcc aactttgtca taagcttctc ctgctgcgtc atctcttgtc tccccaatga
     2041 tttcatatga tccatcttct tgcatataga ctaattctgt atgtcctccg ctaacaagaa
     2101 gtgccatcaa tggaaactgg aatggtttaa ccagacgggc tgcatagata tgccctgcca
     2161 tatggtttac aggaataagc ggcaattggt gtgcccaagc aaaagcctta gctgcagaaa
     2221 taccaatcag caacgagccg acaagtcctg gtccataagt gacagcgact gccgataaat
     2281 cttctgccga cacaccagct tctaccagtg catcttccaa gcataaggtg atttgttcta
     2341 cgtgatggcg gctagctact tcaggtacta cgccaccaaa acgtttatga ctgtttattt
     2401 gagaagcaac gatgttagat aagatctctg ttccatttct aacgaccgct acactcgttt
     2461 catcacaact tgattcaatc gccagaatca attcttcatt catttcatcg tctccgtttt
     2521 taactttctg ctcataatga tcgcatcttc cgtcggattg cgataatatg atttccgttt
     2581 acctaatata cgaaactttt ctgattcata aagttttctt gctgcttcat tagatagacg
     2641 tacttctaaa aaaacatgca gcgaatcttt tatttgttcc gtaatcagta attgtaacaa
     2701 atgccgtgca tgcccttttc cttgttctga aactgcaaca gcaatatttg tgatctcgac
     2761 ttcatctatt actttcgagt atccaataaa gccacagatc tggttatctt cagctaaaag
     2821 cagataatca gagtgaggct gttggatgtc tgccaaaaac tgcattttcg tccaaggtga
     2881 accatgtgga taagcatttt cgctaatcat ccatacgcat tctgccaagt acgcttcatc
     2941 aaaatctttt tttctgcaaa tcaactaatc tcactcattt tctaaaagtt ttatcatatc
     3001 caacgcatct tcttttgttt cagtgtaata tctttttttg atcgttgttg cttgaaaccc
     3061 caatttccga taaagtcttt gtgcatcttg attactcata cgcacttcta atgacatcgt
     3121 ctcacagcga ttcattatag caaagttctc gatttcgtca ataagcagcg aaccgattcg
     3181 tttacgctga tatgccggtc gaacggcaat attcgtgata tggcaatcta aaccgaacgc
     3241 tcttgaaccg ataaaaccaa tcattcttcc attatcaaag atacctagat atagatgagg
     3301 aagcggtgac ttcaattctg atataaaggc actttttgtc catggcaatt cgccattata
     3361 gacttctcgt tcgacatcca gcagctcttt gatatcttct gtagtcaatt ctcttagtac
     3421 gtaacgacga tcgatttgtt cgactgtttt ttctgtataa atcattttat cttgaaaaaa
     3481 gcttctggca tacgctctaa attttttcaa cataactttc gtctccaggt gtgtgcgtct
     3541 ccaaccattt ttcttctgct tctactcgtt ttaaatagcg aggaagaaaa gcttgtttct
     3601 ctgcaactgg ttcaactaaa gcacctaatt gagccacagt tacaccactt ggaatatccc
     3661 atgctggaac tgtattaatc atcgcactag gcaatatttc ctttatttca gagaagaatt
     3721 tgtgacaatc actcccgacg aaataaatag cttcattcag cttttgtagt tgtgtgaaca
     3781 aatcagaagc agaaatatgt acatcttcaa gtacagtttc taatctattt tctttccagc
     3841 ggtatgcccc agcgtataca ttttttcttc gagcatcaaa catgggcaca ataatattat
     3901 ccacaccgat gcaattagcc gcgatggttt tcagactaga tactcctact agctctttat
     3961 ctaatgtata agcaatcgtt tttgctgtcg ttacacctat acgaagccct gtataagaac
     4021 cgggaccatc agaaaccgcg attcggtcaa tgtcttttgg acttatttga agatctgcaa
     4081 acaattggtc gattgcaggc atcagtgtta cactgtggtt gcgtttgata tttgtttgta
     4141 tttgtccaag aatttgttcg tcttctacca caccgatcgc caaagtttgg tttgcagtat
     4201 ctattcctaa tgtaatcata tatttgatcc tttctgctat gacattctcg ccttccattg
     4261 tagcatactt ttttattctg aggatgaaaa taccaaaggc aaaactagta caataataca
     4321 tgattatctg ctggcgggca aattttgccc cttcctgaaa cacaaaaaag ctgcggtatc
     4381 actccatttt cccacagctt ttccatcttt tatttcgttg attctcgaat aatcaactct
     4441 gtttccacaa taatctttct tgaaaccggt gctttggaat tacttaattg aagaatcgtc
     4501 tccactgcta gctctcccat ccattcggta taaactttta cagtagaaag cgagggcgtt
     4561 acatatttcg ctacactgac atcattgaag cccatcacag aaatatcttc tggtaccact
     4621 aaaccttttt cttgaatcgc tttcagtgcg ccaatcgcta atgcatcatt agctgcaaaa
     4681 agcgcatcag gaacatgcgg attcgttttt aaatattgct tcactgcttg atatcctgac
     4741 tcgacagaaa aatctgcttc gataattgga ccttcgtcgt agcctttttc tgccaaaact
     4801 tgttgaaatg ccataattct gggatctttt agccgctgat ggtttttctt cgtatattct
     4861 gttccagcaa gcatagcgat atgttgcgct ttatgggaga caaagtgttc aatgactttt
     4921 tgaacacttg acttaaagtc gacaactaga gagtcgattc cttgagaagt gccgtcagaa
     4981 tctaccaaaa gcaaggcatt ttgggatcct ttcatttcta ataactgagc ttcgtcgaat
     5041 tttcctagtg cgatcgttcc atctgccgga agatcactaa tggaatccca cgtttctttc
     5101 aataaagtaa cgtttgcttc ttctgccttt ttttcgattc ctaggcgaat agataaataa
     5161 taaagatctt caagctcttc cgtatcgtcg taccactgga tcaggcgaag cgtttgctta
     5221 gtatttgctg catttttacg atgtttcgta taatttaagc gttctgctgc ttcaaaaatt
     5281 ttttgctttg tggctaagcc aacggaaaga tcaggatcat agttgagaac tcttgaaaca
     5341 gtagcaggag aaactcctgc caactgcgca atgtctttaa ttgttgccat ttgtctctcc
     5401 tcctttttta cgtttataaa atcgcagtaa atcgttcaaa cgctgcctgt cctttttcat
     5461 ctcgcttgaa tactccagcg tcttccagta cacgtgcaaa aacctgacct acagattttt
     5521 gtacgacatc ggtgaccgta tctttcgtca aatcaggatg ttcttttttt aattgttctg
     5581 cccacggacg atgatattca gccatctggt tttcttctcc taataagaaa tgctctactt
     5641 ctactagttc tggtttcaaa cgaggtggta aaacagcaag ccccattact tcgatcaacc
     5701 caatgttctc ctttttgata tgttggacat ctttatgtgg atgaaaaatc ccatcaggat
     5761 gttcttctga aacattgttg tctcgaagga caaggtccaa ctcaaagtaa ttgtcccttc
     5821 ttcgtgcaat tggcgtaatc gtatggtgtg gtgtaccatc tgctgaaaaa gctctgatag
     5881 atactgtttc atccgaatat gctttccatt tttccaatac tgagttagct gcttcaataa
     5941 gcaagttttt ctctgttgat tgcaaacgga tcacagacat cggccatttc acgactcctg
     6001 cgatgacttg cggataatct tctagtttga taagtttttc tatcggtgct tttgccatag
     6061 gaaattcatg acgtcctgcc tgataatgat catgagaaag aatcgatcct ccaacaattg
     6121 gtaagtcagc attcgaacca acaaagtaat gaggcaagac ttcagtaatc cgaagcagtc
     6181 tagcaaatgt ttcctttgtg attttcatcg ggcggtgttg ttctgataaa atgatcgaat
     6241 gttcattgta ataagcataa ggggaatatt ggaatcccca gctttcaccg tctagattca
     6301 ttcgaataat ccggtgattg gtgcgggctg gatagttcaa gcgacctcta tatccttcgt
     6361 tttccatgca aagcatgcag gtaggatagt ctacttttac cgcctcgcgt tctgctgcga
     6421 tttgttttgg atctttttct ggcttagata aattgattgt gatttccagt tcaccatact
     6481 ccgactctgc cggaaatttg atgttttttg cgatggctct tgttttgatg tagtcatttt
     6541 tcttacttaa attaaagaaa tactcagttg cttcctctgg gcttttcgaa tagtgctgtg
     6601 caaagaatgc attgacgact gaaggtggcg gtgtgagaaa atccattaat tgcgcttcaa
     6661 aaatctcttg ttctgctggc aattctgaaa gaacaccatt ttctcttgcc ttagcgacaa
     6721 gctgatccaa taagtctaca gattcttcct taactggtct tacttcaatg ctttctagag
     6781 catcttctcc taccatccct aaaagacgat tctgtaaata taagcggtcc atttccatcc
     6841 atccgccagc ttcgatcgca agtgtggcaa aatcacaaat cgtttgactg attgacatat
     6901 ctcattcccc tattcttcat aaccatttgg atggctgaca tgccaatccc atgctgtttt
     6961 gataatcgct ttgatatctg tgtattcagg tttccagccc agaatctctc tcgctttttc
     7021 acttgaagcg actaatcggc taggatctcc agctcttctt ggtgctattt ctgctggaat
     7081 ttcttttcct gtcacttctc tagctgcttc tagcatttcc ttgactgagt atcctttgct
     7141 gctgcctaaa ttgaagaagt tgctttcatt tccttctttc aagtattcca aagctaaaat
     7201 atgtgcagca atcaaatctt ctacttgaac ataatctctg atacatgttc catctggtgt
     7261 atcataatcg tctccataaa cagccaaggc ttttctttga ccaagagcta cttgtaaaat
     7321 gattgggaca agatgcgttt ctggtgtatg atcttctccg atagatgcat ctgcttttgc
     7381 tccggctaca ttgaagtagc gcaaagcgac atagcgcatg ccatatgctt ggtcacacca
     7441 cttcatcatt ttttccatca tcaatttact ttcaccatac ggatttttag gattagctgg
     7501 tgtatcttct gtgattggag actctttcgg ctctccataa gttgctgcag tagaagagaa
     7561 tacgatttta ttcacgttga actcgtgcat gacttcaagt aagatttgca taccgtatac
     7621 gttgttgttg aaatacatca atggtttttc gacagattct cctactaaag agcttgcagc
     7681 aaaatggatt actccttcaa tcggttcctt ttcaaatacg gaacgtagaa attctttatc
     7741 ccggatgtct ccttcataaa aatgagcatc tggatgtact gcttgtttgt gacctgtgag
     7801 caaattatct accacagcta cttgataccc cttttgaact agctggtcta cagcgtgcga
     7861 accgatataa ccggctccgc ctagtactaa aattgtcata aaaaacactc ctttgattag
     7921 taaaattgtg tttgttgatt ctatataatt taaaaaacga agtttacttt tatggtgaaa
     7981 acaaacaaag taaaatttcg taaattcata tggtaaattt ataataaaac atttagtaaa
     8041 cattttcaag ggttttttgc aaaggtttac aaacaaacgt aaaactagcc tttttttctc
     8101 ttttgttcca taatagatat aacaaataat aaatgaggtg gattcaatga aaaaatttgt
     8161 atctggaata ttagtaggaa gtctggcaac agccgctgcc gttgctggtt tggttgcttc
     8221 tgtgaaaaaa acagtgatcg atccaattga cgaaaaagaa gcaatgatcg aagaaaaccg
     8281 taaaaaagca atgcgtaaac gcgtttctcg ttaataatta tttaaaaata cgcatgaaga
     8341 ctttctaaaa aacagataag tcatcatgcg tatttttatt tgtcagtcaa tataagttgt
     8401 gctattttat ctgcctgtct cagattccat ggatctgtat aaggtctagc tactgctgca
     8461 gttagccaat ccacaccttc aacaggtatt ccatagcaat aaaagtcaga ctggatttcc
     8521 cctgaagcat caatcacgcg attcgtacct cgctcaacat ctatagcttc tgaatgataa
     8581 cttcctgtat tatctgaaaa tgaaaaaggg cgaacaagtt tgttttcctt caaatttttt
     8641 atgacaggat tacttgaacg agaaaagctt gtttgtggca atcgagcttc aatcaaatag
     8701 cgactgctga tttctttatc ttgtagagaa ataacatagc ggttgtgctt ttgctgaata
     8761 tcaaatggcg gttcgatcaa atgaaaaata cccgcatcta tcagtgctgc taattctttc
     8821 gtccgaatga ttggcggacc gatcgttaaa aagctattta gatgagtaaa ccatccccat
     8881 agtatttctt tgtattcctt agcagaaaaa acgtgccatt caatagcctg ccggattgga
     8941 tcacgccagt cttttaatgc atcaaatgtt gaagcaaatg ctcctgtgca attgcctttt
     9001 tccgcttctt ttatctgccc ttcaataaat attcggctag cttctgaaaa gggctcattc
     9061 tgataggcaa gaggagtttc taaatacgac caatcccatc tataagggat tagtgctgga
     9121 tgctttccga gacactcctc tgaagagagg gagagaaaat catgctcaaa atttttcttt
     9181 ggaatcggca agtgatattc ttcgatgatt ttcttgtaat aaaacaactc aacgtctttt
     9241 ttcagatagt caaaaaatgt ttcgccagtc aaaaatcccg actgatgcca ttgctccagg
     9301 ttttcttttg ttagtaaccg tggccatgcc attgctccgc cttgcttttg atttcttcct
     9361 cgagggtaat aagggagccc ccttcttgat ccactgtata caatcggttc cttgcctgat
     9421 ggatgataga ccagttttcc cttttcgttc tcgaagcgcc ctcctcttga tactgtaaac
     9481 aatccgacat aatcaaaaaa acttaagcct agacctctta aaaagacatt ttctttaggc
     9541 ggtatcttcg aaagatctac atctgcagga ttagaaggaa gctgatacag taaaacattt
     9601 ttctttgcgt agtctaccca cactctttct tcttctgtct catcattttc ccagtgaccg
     9661 cttgctaaaa caagctgatc gatagaatag ctttgctgat ctgtctgtaa aagataacca
     9721 tcttttcttt tgcttacttt ttttactaaa gaataaacaa actgaataga agctggaaat
     9781 tcttcttgca actttgagaa aaaccagcgt tgatagagtc cgtataaaca tcgagtagat
     9841 tgctgatctt tttccagacg attgatttct tctataatta gttgcttatt tttggttacc
     9901 gtctgttcga tataatctgt agcaggtcct ttactccatt gaaacaagtt gggtccctgt
     9961 gttaccaatc ctccactgga caatgtttca tctgtaaaaa gcgtcacttg ttgagaaaca
    10021 gaattcatta ataactccgg tggctgattc aaccgccaaa ctcgacctcc aggaccattg
    10081 ggatcgaaaa gaaaaagttc aagagaatgt ctgtcctgat tattatggag aatcctttct
    10141 gctacactta atcctctagg tccggcacca atgatcccta ttttcatttg catgcctcca
    10201 tttcgataaa ttttttcaat aaaacagcat ggttctgatg ttcatttttt gcaccataaa
    10261 caaaagtaat gactggatgt tctttcataa gttgactgag tttaaaaata gcttgcttct
    10321 tttcttcttc gaaaatcaat tcttgctggt atttctttgc aaatgaagca aatcgttctg
    10381 gtacatggtc aaaagttttg cgtgcttcat tactaggtgc aatttctttc aaccacagat
    10441 ctaactgcgc tttttctttt gaaattcctc gtggccagaa tctatccacg agtattctat
    10501 agccatcctc tttttcagca tcaaggtaaa cacgttttaa tttgatcata gttgtttcct
    10561 tctttctacc ttttcgctta gcttatatat gtagataata gcacaaaata aaaaaaatga
    10621 acggcacaac tatccattgc gccgttcatg tgatcttggt caaaatctaa tgattgattc
    10681 ggtttttaaa gctgtcatac aatcatctgt tttatacttt tttacttttg atttttccag
    10741 accatccgtc atatccaccc ttaagtaaat aaatctcttg ataacctgct ttacgtaatt
    10801 tatttgctgt acggatgctc aaacttttct tttgatcgta aatatagaca ggctggtctt
    10861 ttcgaataga tcctaatgaa tctttcaaaa cagtgtaagg gatgtttctt gcacctaaaa
    10921 tatgcccagc atcaaacaca tctttttcgc gaacatcgat tacttgtgct tttctcattc
    10981 cttctcgaaa ttcttcttct gtcaaagtcg ttgctgaacg tttggccatt actcgtagat
    11041 agacttccca aaggatgatt gcaagcacaa tcaatagcaa aatgatatta attacccata
    11101 aaaccatgta atgcctccgt ttttttaagc aaatttcaag gctaatgagg cagcaccaat
    11161 gacaccagct tcattaccaa gctctgctaa tttgattttt gttgattctc ttacttgcgg
    11221 gaaagtaaat tctttaaaat atttctctac acggctacgt aaaaattctc ctgctgccga
    11281 tactcctcca cctaacacga tacttgacgg atttaatgta ttccccaagt ttccgcaagc
    11341 taaacctaag tagaagcata cgcgatcaac aaccatcaat gcaaacggat cgtcttcttg
    11401 agccatttca aagatatctt tacttgttac ttcttctccg ttgtctagca ttgctttcag
    11461 ttttgaatcc cctgcgtatt cttctgccaa gaaacgacct aggcgtacca cacctgtagc
    11521 gctagataca gtttctaaac atccgcgttt accgcaagta cattcgaacc cttcaggatc
    11581 cacagtgata tgtccgattt ctcctccagc tccgctcacg ccgtgaatca aatttccgcc
    11641 agcaacgata cctccgccaa cacctgttcc tagagtaacg aatacaacgt ctggatcgtt
    11701 ttctccagca cctttccatc gttcacctaa agcagcaaca ttcgcgtcat tatcgatagc
    11761 gaatttgatt cctgttcctg cctcgatcag ttttttcaca aattgaactt ctgtccagtt
    11821 taagttatac gcaccaataa ccgttccagc ttcgctgtcc acgcttcctg gggtacccat
    11881 gccgattccg ataaagtctt cggctttcat attatataaa ttcaaacgat gattgattga
    11941 ttcaatgatt tcaggaacga tatgcttacc atcatccaaa atattggtat cgatgctcca
    12001 tttttgctga atctctcctt ctggtgttaa aattgcaaat tttgctgttg ttccacctaa
    12061 atcaatccca ataatcttct tgtccattac aaatttcctt tctttcggct ttcttcaatt
    12121 cggtgctctc tttttaatat gcgccacgct gtcatgtatg tatcatgatc aatcaaacgg
    12181 ctatcataca gattacgcaa ttcgatagtc attaattcaa tgtcatagat gcgtgcaccc
    12241 acatagataa agatgccaaa ttttttgaac agctgctgta catcatataa gctctccatc
    12301 tttaagcact tccttcatat tatacaagta aaccatattt ttttaaaccc agtaaaatac
    12361 atattacaaa aagaaataca aaaactagtg tagaaagaat cctttggtgt atcgaatagc
    12421 ttgtctgttg tttcggtaga cccaaaacat tccctaacac taatccgcca attagcccac
    12481 cgacatgtcc ccaaacatct acagaggtat ccagaagacc aaaaacaaat gtcaacacaa
    12541 taaataaaag aaaatgtctg actagctgct ggatcgctgg gttatgttta aaatgaaacc
    12601 ctaagataaa caacgcaccg aacaaaccga atatcgaagt acttgcacca ccagacagaa
    12661 cattcgcttc gttaaaagca aagcttgctg tatttcccat tatcccgctg aacatataaa
    12721 tcaagaaaaa acgccaatgg ccatagattg cctcgatttg ctgccccata aaatacagta
    12781 tcagtgagtt cattacgaaa tgcatcagtc caaaatggat gaagattggt gtcactaaac
    12841 gccaccattc attgaagtga acaagataag gaccatacat tccggcataa taagggatct
    12901 caagtcgcgg aaataattcc atcatgagga agaccgctgt ctgtatccct aaaaaagcat
    12961 aggtccataa cggtcgtctt aaccatgcac gcaattttat ttgctgttga taattcatga
    13021 aaacctccca tttcatttta gtcaataaac aattgttgga tcttctgatc aaagctctcc
    13081 ggttgccatt gttcattcaa ttgttcacga aaaacaaggc tacatgtttt tttatgaaaa
    13141 ttatttaaat accggtcgta ataaccaccg ccaaaaccga ttcgataacc ggctctattg
    13201 tagataatac ctggtacaat gaggagatcg atcatctccg gcaaatagag cttctctgat
    13261 tgtggctcaa gaacaccaaa actcgaacgt acaagaacgg actgttcatc catttcataa
    13321 aacgccatct gacgtttcgg caaagtttta ggtacaacta ttttcttttg ttctttttct
    13381 gctcgttgga taaccggctg tgtatccagt tcaaattcat tcgataaagt cgtccctatc
    13441 acttttgctg acttccagta ctcgctggcg aatagctgtt tatagattcg ctgttctttt
    13501 tcctttttct tgccactttt ggccagattt ttcagctttt cgattccttt ccggcgtaat
    13561 cttactttca attggtccaa aaactcaccc ttccttctct cataaaatgg tataggaaaa
    13621 aaagaaaaat agcaatcgaa ctttcaaata aatgcataaa tagaataaaa agaagaccta
    13681 gaaatgattg gccttccttt tttaatgaat ttcaactgtt cagcgcgtgt ttttgtctga
    13741 taaaaagtgc atacagaaaa tatggcgcac caaaaagggc aatcaaaatt cctgtaggta
    13801 cttccccact tggtagaatc actctagcaa ccatatctgc actaagcaga aaaatggaac
    13861 cgaacaaacc gctcagaaca aaggtccagt tattttcttt acgtacgact agcttcgcag
    13921 catgaggagc tagtagtcct acaaaagata aactacctgt caccgctaca ctaccgcttg
    13981 ccaaagcaac agctaacaac aaaaggattt tttgactttt agccacgtta aggcctaatc
    14041 cttgcgcgcg ttcttgacca aatgatagca atacaatcct ctgtgcataa agtcctccta
    14101 gcggaattaa gataaccgcc catggaagca atgcccaaac ataaggccag ctcgcacccc
    14161 agattgatcc cgctaaccat gcattcacaa atccataatt ttccttagat aattggatcg
    14221 tgcatagcaa tgttaatgca gaaaggccgg cattaacggc aataccggac aataagattc
    14281 gattcatacc caaaaagcca tttcgatcat aggccgcaag atagacacag caagcagcta
    14341 aaacaccacc tagaaaggct acaactagca atagaaacgg cagcgaatag tgcgaaaaga
    14401 aacctaaata aagcatcact aaaaatcctg ctccggcatt aatgcccaat atactagaat
    14461 ctgccaattc atttcttgtt actccttgca agatataacc agaaacgcca agacaagctc
    14521 ctgctaataa actgatcagt aatcgaggaa ctcgaaattc tctaacaatc agcgccaaag
    14581 aagatgattc tttccctatg aacgtggcaa aaagctgatc caggtaaata aaaggcgtac
    14641 caatcattaa actacctata gacaggatga caagtacaaa aagcaagaaa tagaacgtcc
    14701 aatatatttt tttcaccgtt gttccctcct tacttgtatc agtaaaaacg gaacgccaat
    14761 caatgcaatg actaatccaa aaggtgtttc aaaaggggga ttgatcatcc tcgctgtaaa
    14821 atccgccaac ataaccaatc caccgccaac taaaaaagag acaggtagaa cataacgata
    14881 gtccgttcca accattccgc gaacaactgg cggaaccaac agcccaataa atgaaacagg
    14941 tccgactaac gaaacggcaa tggctgctaa cactgcaact agacagaaaa caatcaaccg
    15001 cgttcgttta ggatgacttc caagagctaa tgcatgtgtt tcactcaaat gaatcaaaga
    15061 tattgctttt cctaatgaaa aagaaaccaa aacagcaagt atatataaag gaaacaatac
    15121 tgctaattgt ttccatgtga tattggcagc tccgcctaca aaccaaaaag caagatcctg
    15181 ctgcagatta aagaattggg taagtgcttg gctgatagca gtaaaaaaag aactaatagc
    15241 tacgccagct aaaatcagct gtaaaggatt catgcccatt ttcgaaaact gcaaaaaacc
    15301 aaatacgagc aaagttacag caaaagaacc tgccaatgac attagaaaca cagaaaaatc
    15361 agaagcttta ggccaaaaag caaaactaag ggccattgcc aacgaagcac ccgcgttgat
    15421 tcctagtaag cctgaatctg ctaaaggatt tcttgtcact ccttgcatca atgcaccgct
    15481 caatgcaaaa caactcccta caagaaatgc tcccgccaca cgaggcaaac gaatatttcg
    15541 tatgatttgg tgactttgtt ttgatctatc aaaatcaaac aacgcctgcc aaaaatctgc
    15601 tttttccaca gtcgctgcgc catttgaaag agcaacaaaa aaaataatca aaagaacaaa
    15661 acagaccaaa agcaggagtc tatttttctt catagtcctc ataattgatc ctcctgctct
    15721 tttggcaaca aatcataggt tagaaaaact ggtttatttg ttcttggaag cgtgacaatc
    15781 gttgcatcaa tctcaaatat ttttttcata cactcttttg tgatcacttc ttcaggtgta
    15841 ccttctgtga tcaacttacc gtttttcatt gctaataaat aatctgaaaa acgtgaagca
    15901 tgattaatgt catgaatcga catcaagatc gttgtttgtt tcatttgatt gatttcagtc
    15961 aataactgta ggatctctaa ttggtgtgcc ggatctaaaa atgttgtcgg ttcatccaag
    16021 atcaagatat ctgtttcctg agcaagcgcc atagcgatcc agacacgctg ggtttgtcca
    16081 ccagacagcg ttgcgatatc ccgcatacga aatccagcta gacctgtagc atccaacgcc
    16141 cactcaattg cttcatgatc ttgcgtgtcc atgccactga acagtttttg ataagggtat
    16201 cgtccgtaag atactacttc ttctactgtc atacctgtag ggtgttcact agtttgtgct
    16261 aataatgcaa ttttttttgc aagttctttt gaactgtatg tagagatatc agagttattg
    16321 acaatgatct ttcctgattt cacaggtagt atacgggtaa aacttttcaa taaagtagat
    16381 tttccacttc catttggccc aatcaaacta gtgattttcc cttcaggaat cgtaacagac
    16441 atgttttcaa tgattttttt gttttcgtag ccggctgcaa tgtcagctgc tcttaatctc
    16501 gtcatttcac ccatcctttc gctgaaaatc attctcaatt atgacgctgt ttcaacattt
    16561 cgtcaagcgc tactttcata tctatagcca aatgaagcgg ttgacagcgt tcgaaatatc
    16621 aggaataata accaatgaga aagattctca attatgttag gaggaaagaa atgaaattaa
    16681 aaacaaaagt attcacatta tctagcatat tgctgctggc tggagtactg agcgcttgct
    16741 ccccctcttc agataaagaa acagctacaa ctgccaattc gacgacttca tccaatagta
    16801 ctcatacagt cacagataca cttggacata aagtagagat tccaaacgcg cccaaacgga
    16861 tcatcggcag ttacttagaa gactatctga ttgcactagg ggaaaaacct atcgcccagt
    16921 ggactgttgg cagtggttcc attcaagatt atctgcaaga tgatttaaag gatgtcccaa
    16981 cgatttctta tgaccttcct tatgagaaag tgttaagctt tgagcctgat ttgctgttga
    17041 tttcttcttc cgctactgtc gaaggcggga aatacgaaca atatagcaaa atcgcgccaa
    17101 cttatgttgt aaaaaacgga acagatgtca catgggaaga acaactaaaa gatgtcggca
    17161 aagctttggc aaaagaaaaa gaggcagaaa aaatcatttc cgattatcaa aaatccatca
    17221 agaaaactcg agaagaacta gcagataaaa tcgagaacaa gacagctgca gtgttgtggg
    17281 tgaccaacaa ctcagccttt atggtcagca aaaatcggtc aagtggaaga atcgtatacg
    17341 acgatctgga atttggtgtt cctgatctag tggaagaggt ctccaaaaaa gccacttctg
    17401 actggtctgc tgtttcctct gaaaagctag ctgaattaga tgctgactac atcatccttg
    17461 tgaacagtga caaagatgct gccatgttca atgaaccaag ctggaagaat ctaaaagcag
    17521 tgacagacaa tcatgtactg caattcggac ctgaatctag ttggctatat aacggaccta
    17581 ttgccagtca ggaaatggtc aatgatatca aagaaaaact aaattgattt taactaaaaa
    17641 aagcatcttc acgattagtc gtgagatgct ttttttctta ttaacaaact agacgcatag
    17701 attttattct tcttttgaag caaccctatt ttttactctt tcccattttt gaaaacgatg
    17761 ggcatataga ttttcttgat ccgttatccc ctcatactcc tctataaggg cgaagtctga
    17821 aaaatcaata ttcccaatat acgtatcgcc ttcaaacgtg ctatcgatca atgttcgcca
    17881 gatccgacca gtgtaaggaa gaagttcttg aaaaatccga ctaccacccg aaacatagat
    17941 atcttctgag atcgtttgac tatacgacaa aagttcatcg atcgaatgca ttacttccgc
    18001 attttctttc gtgcgaaaat ttggttgcgt tgtcaacacg atgatatggc gataaggaag
    18061 tgaaagatcc cccattcctt cataggtctt tcttcccatc actaaaattc gatccattgt
    18121 atgttcgcga aagaaacgca tatcatttgg caatcgccat ggtaacaaac catttttgcc
    18181 gatcagacca tttttatctt gtgcccacat ggaaataaac atattatccg ctccttatga
    18241 ttttagatgt tttgagataa aaaaagtctc aattctttga ccagcaagga attgagaact
    18301 ttaaaaacat tattttgttt cacggtgcaa agtaactttg cgttcgcgtg ggcaatattt
    18361 ttgtttttcc aaacgatcag gattgttacg tttgtttttg cttgttagat agttacgttc
    18421 tttacaagaa gtacactcta aagtgatgtt tacgcgcatg tttttccctc ccatttttac
    18481 aagaatcctc taagatgact ctcagacttg attatcttac catgattttt tctagattgc
    18541 tagtgttttt cacgattttg ttaagtaaaa ctacttgacg ataaatacaa cggttttact
    18601 tctcaaacaa aatctttttc tttttgtata aataccctta cacttgttta tatagattat
    18661 gttttttaat aaagggggat actaatatgc catggaacat gaaggacttt cctgcatcaa
    18721 tgaaaaactt agataaattg acaagaaaaa aagcaatcga catcgcaaat gcattattag
    18781 atgaagggta ccctgataac cgtgcgatcc caattgccat tgatcaagca aaaaaatggt
    18841 atgaagatgc tagtgaatca gaaaaacgaa ctttcgaaaa agaaaaaaat ccaagcaaga
    18901 cggatgaaca cgatacgaat cctcgtgctg gaaaactgct tgattcagat gtgatcgtag
    18961 aatatgagga agaacaatgg atcgtgaaat ctaaaggggc aaaaaaggca agcaaccatt
    19021 ttgatacaaa aaaagaagca atcgaaaaag gaaagcaagt agcacaaaac aaagaatcaa
    19081 ctttgttcat ttataaaaaa gatgggacaa aagaaaaaga aatcgattat tgaacatatg
    19141 taaaggggtt gtgacgaaaa tcgtgtcaca acccccttat gttcgaaaca atggtgttcc
    19201 tctgccaact ccgaaccata agtcataata tctataaaac gggaagagct gttttttgaa
    19261 attgtttctt atcactcagt gttaaacggt aggagaaaac ctctttttta ttgatatttg
    19321 attttcatca aacagtcaca tagtcgattg cttctgcttg cggaatcgtt tcatctacaa
    19381 agtagacttt ataccatgtc aagaaactga agattgtcca gatttttctt tgctcttctt
    19441 tacgtccttc gtgatggtca tctagcaact tcatgatttt ttcttgatca aaaaattctt
    19501 ttgcaaaatc tgcttcgaat aatgctttga cttgttcgta gccgtgttct tctttcaacc
    19561 aagctttgat tggcacaggg aatcctaatt tcacacgatt cgaccattct tccggaagat
    19621 gtttgttcgc agcttgtctg aaaatatctt ttgtgttgtt ttgattcaat aaaaacttac
    19681 ttggtatttg ttgagccaat ttcatgactt cgatatccaa taaaggtact cggacttcca
    19741 aagaacttgc catagaaagt ttatctgcct ttaacaagat atcttttggc atccattgat
    19801 gaagatcgac atattgcatc ttattgactt catctttgat tccttctgtt ttctcgtaat
    19861 gaacagtcat gatttcatcc acagatggtg ctgtttgata ttttggtgtt aacacttctg
    19921 atgcttctga ttcttcgaac actcgagcat gaccgataaa atattctttt gcaggagcaa
    19981 gtgattcata taaatggatc cgtccatgga agtttttcat ttttccgatt ttacgtccta
    20041 aattatagcg tgttcctttt ggtaattttt tcaatccttg agcaatcaca cggatgaatt
    20101 ttgaattcgt atggaatcca tacgtttggt atcccgcaaa cagttcatcc gccccttctc
    20161 cagattggac tacccgcaca ctttgtgaag caagatttgc taaaaagtac aaaggtacgc
    20221 aagaaggatt tgaatcaggt tcatctaagt gatactggat caaagggaat gctttgaacg
    20281 acatgtctcc gtcgatcact gctgctgtat tatctaagtc caatagttcg gttagttttc
    20341 tggcttcaat cgcttcatta taggttttat catcaaaccc gattgagaaa gaatgatctg
    20401 gtttcaatac agaggttaca taactggaat caaccccgct ggataagaaa gaaccaactt
    20461 ctacatcact gaccgtatgt gcttcaatag aagcttgaac ggtttcgtcg attttttcga
    20521 tccattcttg tcgggaatgc gtttcttttg tttcaaaatc tgcatcccaa tattgctgaa
    20581 tgtctatttt tccatcttta tacgtataat aatggccttc aggcaaacga tagacatctt
    20641 tgaagaatgt ttcgccgttt aatggagaat attggaaagt catataaggt ttcaacgctt
    20701 ctttgttcaa ttctttgtta aaatcaggat gaggcagaaa acttttgatt tctgaaccaa
    20761 acataaatgt tccgttcatt tctgcataat aatatggttt gatcccaaag tggtctcttg
    20821 caccgaataa ctcattcttt tcattatccc aaatagcaaa agcaaacatt ccgcggatct
    20881 tttgcaataa ttctgttccc cattcttcgt aaccatgcaa aaggacttct gtatctgcat
    20941 gtgtttgaaa aacgtggcca gctgcaatca attcttctct caaaggctgg taattataga
    21001 tttcgccatt aaaaataatg atctttgtcc gatcttcatt gtaaataggc tgagtaccgc
    21061 cctctaagtc aataatactt aatcttctga atcctaaagc aacatgttta tcgatatatt
    21121 ctcctgaact attaggtcca cggtgaacga ttcgatccat cattgtatta ataattgttt
    21181 ttttgttgtc cttgtcgtta acaaaaccta caataccgca catttaactt tcacatccta
    21241 atataaaatt actgtttatt tcattcatat gcatcttatc atagaataaa tagcggacga
    21301 atattttctc tcttacaatt tcgtcacgtg aaaacaaaag atgaaagttt ctgtttttac
    21361 agaaaataaa gtcccaatat ctaatttacc atgttttctt ttttgaggct accttattct
    21421 cttcgtgtta aaaaaatatt agtggatgct atttccaaaa aaaccagcaa aaaaagacac
    21481 gacctaaaga tcgtgt
//
LOCUS       DADVXK010000040        20886 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.040, whole genome shotgun sequence.
ACCESSION   DADVXK010000040 DADVXK010000000
VERSION     DADVXK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.040"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            112..306
                     /locus_tag="KB909_001420"
     CDS             112..306
                     /locus_tag="KB909_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837463.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="KB909_001421"
     CDS             575..874
                     /locus_tag="KB909_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837464.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="KB909_001422"
     CDS             complement(971..1405)
                     /locus_tag="KB909_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837465.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="KB909_001423"
     CDS             complement(1637..2347)
                     /locus_tag="KB909_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6837466.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="KB909_001424"
     CDS             complement(2337..3197)
                     /locus_tag="KB909_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBB6837467.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="KB909_001425"
     CDS             complement(3202..3840)
                     /locus_tag="KB909_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBB6837468.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="KB909_001426"
     CDS             complement(3855..4154)
                     /locus_tag="KB909_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837469.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="KB909_001427"
     CDS             complement(4197..5681)
                     /locus_tag="KB909_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6837470.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="KB909_001428"
     CDS             complement(5701..6162)
                     /locus_tag="KB909_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6837471.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="KB909_001429"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="KB909_001429"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBB6837472.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="KB909_001430"
     CDS             7465..8235
                     /locus_tag="KB909_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6837473.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="KB909_001431"
     CDS             complement(8508..9335)
                     /locus_tag="KB909_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6837474.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9903..11138
                     /locus_tag="KB909_001432"
     CDS             9903..11138
                     /locus_tag="KB909_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBB6837475.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12137..12397)
                     /locus_tag="KB909_001433"
     CDS             complement(12137..12397)
                     /locus_tag="KB909_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6837476.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12424..13725)
                     /locus_tag="KB909_001434"
     CDS             complement(12424..13725)
                     /locus_tag="KB909_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837477.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14017..14475)
                     /locus_tag="KB909_001435"
     CDS             complement(14017..14475)
                     /locus_tag="KB909_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6837478.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14488..15819)
                     /locus_tag="KB909_001436"
     CDS             complement(14488..15819)
                     /locus_tag="KB909_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBB6837479.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15830..17272)
                     /locus_tag="KB909_001437"
     CDS             complement(15830..17272)
                     /locus_tag="KB909_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6837480.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17259..18023)
                     /locus_tag="KB909_001438"
     CDS             complement(17259..18023)
                     /locus_tag="KB909_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBB6837481.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18127..19002)
                     /locus_tag="KB909_001439"
     CDS             complement(18127..19002)
                     /locus_tag="KB909_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6837482.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19257..19341)
                     /locus_tag="KB909_001440"
     tRNA            complement(19257..19341)
                     /locus_tag="KB909_001440"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19305..19307),aa:Leu,seq:caa)
     gene            complement(19359..19430)
                     /locus_tag="KB909_001441"
     tRNA            complement(19359..19430)
                     /locus_tag="KB909_001441"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19396..19398),aa:Gln,seq:ttg)
     gene            complement(19440..19512)
                     /locus_tag="KB909_001442"
     tRNA            complement(19440..19512)
                     /locus_tag="KB909_001442"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19477..19479),aa:His,seq:gtg)
     gene            complement(19574..19658)
                     /locus_tag="KB909_001443"
     tRNA            complement(19574..19658)
                     /locus_tag="KB909_001443"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19622..19624),aa:Leu,seq:caa)
     gene            complement(19679..19749)
                     /locus_tag="KB909_001444"
     tRNA            complement(19679..19749)
                     /locus_tag="KB909_001444"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19715..19717),aa:Cys,seq:gca)
     gene            complement(19795..19866)
                     /locus_tag="KB909_001445"
     tRNA            complement(19795..19866)
                     /locus_tag="KB909_001445"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19832..19834),aa:Gln,seq:ttg)
     gene            complement(19878..19950)
                     /locus_tag="KB909_001446"
     tRNA            complement(19878..19950)
                     /locus_tag="KB909_001446"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19915..19917),aa:His,seq:gtg)
     gene            complement(19953..20026)
                     /locus_tag="KB909_001447"
     tRNA            complement(19953..20026)
                     /locus_tag="KB909_001447"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19992..19994),aa:Trp,seq:cca)
     gene            complement(20033..20113)
                     /locus_tag="KB909_001448"
     tRNA            complement(20033..20113)
                     /locus_tag="KB909_001448"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20077..20079),aa:Tyr,seq:gta)
     gene            complement(20115..20190)
                     /locus_tag="KB909_001449"
     tRNA            complement(20115..20190)
                     /locus_tag="KB909_001449"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20155..20157),aa:Phe,seq:gaa)
     gene            complement(20226..20298)
                     /locus_tag="KB909_001450"
     tRNA            complement(20226..20298)
                     /locus_tag="KB909_001450"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20263..20265),aa:Asp,seq:gtc)
     gene            complement(20308..20380)
                     /locus_tag="KB909_001451"
     tRNA            complement(20308..20380)
                     /locus_tag="KB909_001451"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20345..20347),aa:Val,seq:tac)
     gene            complement(20396..20467)
                     /locus_tag="KB909_001452"
     tRNA            complement(20396..20467)
                     /locus_tag="KB909_001452"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20432..20434),aa:Glu,seq:ttc)
     gene            complement(20482..20571)
                     /locus_tag="KB909_001453"
     tRNA            complement(20482..20571)
                     /locus_tag="KB909_001453"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20535..20537),aa:Ser,seq:gga)
     gene            complement(20611..20684)
                     /locus_tag="KB909_001454"
     tRNA            complement(20611..20684)
                     /locus_tag="KB909_001454"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20648..20650),aa:Asn,seq:gtt)
     gene            complement(20694..20809)
                     /gene="rrf"
                     /locus_tag="KB909_001455"
     rRNA            complement(20694..20809)
                     /gene="rrf"
                     /locus_tag="KB909_001455"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6580 a         4385 c         3325 g         6596 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9601 taatgacgac agcacaccta tcaattaata taattatttt atttttttat gttctcatgt
     9661 ttatttttaa tgacacaact tctcgtattt atctggcaca acatataaat cgatcaaaaa
     9721 attgttgcgt gtttttttga aaattggagt ttcaacttga ttacaaaatt taaatttaga
     9781 agttgtgaaa acagcgagag acagtttaat attcaaaata tacataggct actcgaacgc
     9841 tgtgtttttt agtatactag taagaaacga agggatagac tcattccaat aaggaggatt
     9901 tcatgaagac aattcttttt gctcctgcag tattcaattt agctgagaca acacgaatga
     9961 ttgaggttgc caaagctatg aaagaccgtt attactgtgt attctttggc ttttctaaaa
    10021 cttttgctcc tttgatcaca gaaagtggct ttgagtatca tttactagcg ccgatcctta
    10081 cgaaaaaaca agaagaacaa atcataaaat ttgaccagtt gcgtacactt aaaaaccctt
    10141 ttaccaaaga aatggttgcc tctcgtatca ctagtgaaca gagtctgatt gctaagtttg
    10201 agcctcgact gattgtgaca ggttcgaatg tgacaatttt tttatcggcc cgcaataaaa
    10261 agattccttt agtatatgtt aaaccctatg ctttgagtga accttttttt caatcagagc
    10321 atgcgctgat gccccacgag ttacgtttct tcggcccttt aagcaatccc ctttggcact
    10381 ggacaaaaaa gcgtatagta aatacccgat ggatccccaa tgccttcaaa cacgctgcac
    10441 aaaaagaaat gcttccttta ccaaaaacaa gtttacaaat gatggatgct gatctaaatc
    10501 tcatcacaac gcctaaacta tttttggaag aagaacagct gccggaaaat tatcgaatcg
    10561 ttggtccaat ttttgctaag ctcagtactt ccttgcctga agaagtgcta acttttatac
    10621 agcgaaagca acaagaaaga aaacgtatta tctatttcgc aatgggtagt tcaggcaatc
    10681 cgcgtatgtt acgcaaaatt ttgttcttct tacaaaaaca accggatcta gcggttattg
    10741 cacctattga ctatctgctt gatgacattc aatctgactc agaagatctt ttaataacag
    10801 aatatctgtc tagtcatctt ttgcatgaat tcattgattt ttcttttatc cacggcgggg
    10861 aagggaccgt ccaaactgcc tgtgaatccg gcaaaccgtt tatcggtgtg gggatgcaat
    10921 ttgagcaaag ctgtaatatt gactattgtg taaaatacgg aaacgcaatc gccctcacaa
    10981 aaccagtgac tgaaagaaaa ctgcagattg ctctgcgcga agtttcttca cccaagattc
    11041 gtcagcaggc acgcacgctg caagccgttt ttccaataaa tggtccacaa caagcaattc
    11101 aagaaatcga aaccttcctg agcaaccacc caatatagtt tcaagtagaa aaagcttttt
    11161 taatagagac tcatcagtaa tttcgctatt cgagacccag acagtgaaaa tacaaaaaaa
    11221 gtaaatagtg gattgaaaag ttagagttac ttaaattacg gtgtctaaaa aacacaaaat
    11281 catccttaaa ataaaagatc tgacgctatc caaatgagca taggtagcgt ctgccattta
    11341 ttcttagtca aattctttga cacctttctc tggttggatc atctcaacgt ttcttcaaaa
    11401 gaaagaccat aataattagg caaatacatt ttcttaaaat gtgtcatata gatctagaag
    11461 catcgctttg tagagatttg tgccgctagt cccctcaaca attactaaat caaatgtagg
    11521 atttaccact ttatctttga taatcaacct ccctcttctg ttgagacaat gatctcgcaa
    11581 tccgatgcat actcctatat aaactgccag caatccccac atattgagta gatcatgtca
    11641 gaatgttcta tgtcgtcagc aacgatacac taaaagtcac gttcaccatg actgattgct
    11701 attcccagca caattatttc tatacacgtt tcatgatttg aataaacact cacatcatac
    11761 atattaccat tcatacacca tactgcagcc cctactatat ggttgtaagc tcccaaatct
    11821 atatttgact tgatcacttt ggtagtagat ctactaattc taaatccatt gctgataaaa
    11881 tttccatttt ttcctccttc tttctgccaa aacagttaaa acaataataa tctttatgta
    11941 aaaaagggct gtgacaaaag ccttgtcaca gtcccatatt ccgaataaac ggtggtcaaa
    12001 agcttgcatc tgcggtaata agttcaacca aacgaaaaat aagccaacat ttcacaaaaa
    12061 tttaagaagc aattttcgta aatttcttct tatttcttga agctaaccac ttctgttaca
    12121 accactttta gaacatttaa agcttcgatg tgacaaacca tctatgctgc tcgatcataa
    12181 aattgatagc aaaaattcca caaagtacat atgtccccca tgaaaacaaa acattcatat
    12241 gcggtacaat gatctttgga agaatcacga tcaaaaatga tgccagtgcc caaatccatc
    12301 gattgatttg aatatgatat gtagctagca tattcaatat aaggtgacta gccgttaata
    12361 aaaagataaa aacaaaaaat aaaatcagcc aatacattgt ttcccacctt ctaaaaacca
    12421 aacttagaca gtctggactt cgttttctcc acgactttgt tcatctgaca gcatcttttt
    12481 atcataagct tttacaaatg gataatagat aataaatgct atcaatgtgt tgatcatgat
    12541 caagataaca acacgccagt catttcctgc tgaaagataa ccgccgattg gagctggtaa
    12601 tgtccatgtt ggcaaaacag taaatctatt gaccatttct aatttgactg caaaataact
    12661 gataatagtc aaaactaaag gaactaagtt gaacgggatg aacatgtaag gattcaacat
    12721 cataggagct ccaaaaatta tgggctcatt gatattgaag ataccaggaa taatagaaaa
    12781 acgaccaacc tctttcaaga attttgattt acagaagaat ataaacaaaa cagataccac
    12841 gatcgttgct cctgcaccac caattgttac cgtccattga taaaactgtt caggagcgat
    12901 atagggtaat tgggtggcag ctgtaccatc tgccaatgcc tttgcattct catccaacat
    12961 gatcagccac attggacgaa caacagcccc tacaatactc atgccatgga taccaaatga
    13021 ccacaacaaa tggatcaaaa acattggtag taaaacacca agcaaattat tccctaaaat
    13081 attggttaaa ggctcgaata acgataataa ggcagcgttt acatcaaagc ccgcgacgct
    13141 tcgaatcagc caagtaattg ttaaaatgac tgcacctgga atcaatgcct caaaactacg
    13201 ggcaacagca ggtggcactt gttctggcat tttgatagta atatttcgat ttttaaagaa
    13261 acgatatact tccactgcaa aaatcataga taagatcccc gcaaacatcc cagatgctcc
    13321 caaagaactc ataggtaaga cccagccaag aggtgcctct tcaggagtta aaacgtttac
    13381 aggaacttgt aacataaaga acgttcctaa agataatata ccacctgtca cactatctaa
    13441 tccatatgat ttagctagat ccgaacccat aacaaaagtt gcataaatag ccatcaatcc
    13501 catcgtcatc ctaaagggta aaacaatcgt tgccgaataa ggggcaataa attcattcca
    13561 tccaggaaac ggtaaattga taaagaccat aaaaaatgtc ccaatcaaaa tcaatgacaa
    13621 tgttgaaaca accccattac gaattgctaa taaatgacgc tgtgtaccaa tttttgccat
    13681 tggtgggaca agtttctctt cgacccattt catcagcttt tccactaaaa ccactccttt
    13741 tcaataaaat atgaaccatt cattgcatga caacgcaaag aatgttcata actaattata
    13801 taattaagaa attttatttc aatatattct cttaaataat caaatttatt tttaagaatc
    13861 ctgaaaataa gttttctaaa tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc
    13921 aaaatgatta aatctagtga ttgaaacata tcatttcaaa aaaattttgt aaattcaccc
    13981 ataaatatca ccctatttaa cttttttcat cgtacactaa aattcaaaac aactatcttt
    14041 aatctttact tcttggtttt gttttaataa atttccttca aaaatgcctg gagaaactac
    14101 aatgatcacc gtatcttttt gtgcttgctc caacttcttc aaatctataa tagctaacag
    14161 tgtcccttct tttacctcct ggttactttc aacccgtatc tgaaacggac ttccttcgag
    14221 ttcaactgta tctaaaccca tatggatcag tatttttctg ccagattcac tttcgatcgt
    14281 tatggcatgt cgggtaggaa atatattatc gattattcct ttaactggcg catggatata
    14341 tccatcatga ttcgttatag cgtatccaac tcctatcatt tttgaagaaa agacctcgtc
    14401 ttttactgct gttaatggaa taatttgacc actagctaca gcttttagaa tgtttcttgt
    14461 tttaaagaaa tgcacttttt atcacctcta ctttaatgct ggccaatatt ttttgtttac
    14521 tttgatcatt tcatctagta ttttttttgc gactctggca tttggtacgg tttgattcaa
    14581 tgtaaatgct tgtaaagctt tttgataaga accttcaaag taagcatcta ctagtaactt
    14641 ctctactgca acttgtgcct ccatcaatcc tttatgaaaa tcactgattg gttttcttag
    14701 tgtaattggc tccacaccag ttgcaccaac atatgccggt atttcaacaa ctgcatctga
    14761 ccgtagattc ggaatcgccc cttgattagg aacgattagc ataaagcgac gacgatcatc
    14821 attcaacaag gaaatagcta tatcgacgat atattgtcca tgctccccaa aattaaagtt
    14881 caatacttct tccacaatac cgcggcgtat tttatcagcc atttctttgg tatttttctc
    14941 tcgtccatcc atgaccatat tagcacgtgt atactctttg tcagtatgct caacgaccat
    15001 atcaggatat aagtaatact ctaagtaatt attcgggata ttacttggaa aatttttcgt
    15061 gatgactgac atcatttgaa aggttttttg ccaagtttta tctcctatat taaaatcggc
    15121 gacttgcatt tcttttgtta ttagtttttc aataatctct ggcataattt ctcgttgcaa
    15181 ttctttatca taaatcgatg tataccagcc aaagtggttt aaaccataat acgtaacgat
    15241 ccaattctta cgatcataac cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat
    15301 atcacaggca ttaatcattt ttacattcgg atatttacga cgaacagctt cagaaacgat
    15361 cgactctgga tttgtataat tcaaaatcca tgctttgggg gcatagtctt gtatatgatc
    15421 gacaatttcc aataaacctt tgattgagcg catcccataa gcaaatcctc cgagtccaca
    15481 cgtttcttgt cctactaatc catgtttaag tggaatcttt tcgtcctttt ctcgcatctc
    15541 caatcctcca acacgaattt gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg
    15601 atcatccgtt gcacgaatgc gaatatttga aaaacctttt cttttcagca taaatttaac
    15661 aatcaagtac atatccatat ttctttcttc atcaatatca tataaacgta tttcagataa
    15721 tggcaaccgt ttttcattgt tcaaaatggc ttgaacgatt cctggtgtat acgtactccc
    15781 gcctccagct atagtgataa tctgtttttt catcatcatc ttttcctttc tattcttcta
    15841 ataatttatt gaattctgcc ataacataag tcacttctaa gccgatgata atttgataat
    15901 ttttttcagt tggtttaatg atcccgctta tccctaattg cttgattcgc tgttcctcga
    15961 ccatggtggg atccactacc tctacccgta ggcgtgtatt acaactatag acatccagga
    16021 tattggcttt tcctccaaac gcttgtagca tttttgttgc catatattca taatttttac
    16081 ttgctaaccc taactctgtt tcttctaagg ttacttcatt gccaaactct gccttagctt
    16141 cacgtcctaa tgtctgaatg tttctcttat tgatcaaata ataaaaagta acgtaataca
    16201 aggcaaaaaa gaaaattccg attggaagaa tcaaaatagc attggtagcg attcgaaaat
    16261 tgatgagata atcaacaata catgctccga atgtaaaacc aattcgtata ttgaataagt
    16321 aacagacaat ccctgctaaa ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa
    16381 gaaacatgaa actaaattca acaggctcag tgatatttgc aataaatgaa gttcctgcac
    16441 cgcttcccat gattcctttg accatctctt tattttcttt ataagctgct ttatagatag
    16501 ctagacatat agctggtata ccaaacatca ttactacaaa aaaaactgat aaaaacagtc
    16561 cagcctgagg atctccgttg ataaagcgtg tcatctctcc tctgaaaact tccttgctag
    16621 gagatgtata gcttcctaaa tcgtaataaa tatacgtatt caacacatgg tgcagtccaa
    16681 aggggatcag caaacgattc aaaaacataa atatccccac acctaatgct cccatatcaa
    16741 cgagcagttt tgcaaaatta tcaatcccaa tttggatgag cggccagata aagcccaaaa
    16801 aaacagctgc gattgtttgt agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa
    16861 aataagaaaa aactactggt aatttttgtt ctttaaagcg attatacgtc catgccgcta
    16921 ctaaaccgga aataattcca ccaaaaatcc ccatattcac ttctgggtcc ataatttcta
    16981 agcctttttt caaggtagca atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct
    17041 tatttttgac aaaaccgatt gcaactccta tagcaaataa gatatccaag tttccaaaaa
    17101 cggcatttcc agctgcacca attactggga tgttcagcat atcgtcagct gataaacgca
    17161 tgatcaatcc cgctaatggc atcgctgcaa ctggaagtag catcgctctt ccaagcttct
    17221 gcacatttga tttaacattc atttttattc ctcctctatt aaatatcctc atatgttact
    17281 aactcaatca aaggatcatt tttcactttt tgagcaaatg ctgaatgaat taaaaattcg
    17341 acttggtggg tacgaggata cacaaaactt gaaccattta acaattcctg atccaaatac
    17401 gctgcgtgac acatgacttc gatcgtttta tcttctctca atatcatgag taaacttgcc
    17461 aaatattctt ccacactcgt attgatttgt cgtttttttt catcagtttc tcctacgaca
    17521 tcgaaacaag gctcaaaata atcgacatga cgaacttcat cttttcgttc aaagttgctc
    17581 cgaaccggca aatcatattt ttttgctaat gtaacaacta cctcctgatt ttcatccaaa
    17641 gtatgagtat gatgatgact gtctaaatga gttggtatga tccccgcatg ataaattttt
    17701 tgaatctgag cattccattc ctgatacagt tgatctttgt caatgttaaa tggatgctga
    17761 taataagata aggatctgaa ctctccgctt tcgataagag tatcgacagt tttgaggagt
    17821 ggtttgccac acgtcaatgt taaatggact cctacaccta gcctaggcat ttcctttctt
    17881 agtttcacag catgctcgaa acccggcata tttgccatca atgtagttga tgtcaaaatt
    17941 cctcgctgat aagcatccat aatcccataa ttcacaccat ggctatagcc aaaatcatcc
    18001 gaattaaaaa tcacttttcc catttcattc tccttctttt ttctactaaa ataggcgcaa
    18061 ccaaataatc atagtccatt tactatgtgt catttggttg cgcctataga tagttacgcc
    18121 cttattttaa tagattcttg ctagatgaat tgccaaatag atgatttcat tttcttgaat
    18181 ggcaagttga aattgctgtt cgatgatatc tttaatcttt agtgctgtac aatacgcttt
    18241 gctatgttta aatgtttcag taaaaaaacc aatattttct actggcgttt cttcctgata
    18301 aatcaagcgt ttaaccagga atttgatatg aaccattaag cgatgataag tcagtgattc
    18361 tttatcataa acgtttgaat aggatttttc tagatgggac aaaatcgtgg tcgtcatttc
    18421 tactattttt aagctcttta aactattagg ctctcctagc tcagcattaa tgatatgcat
    18481 agtgatgaat cctacttcat ttgaccctaa ctcggtttga tatcgatgat tgattcgctc
    18541 gaccacttct actgctatat catattcatt tggataaagg aatctcattt ctggcaacat
    18601 aattgctgtg acatctctat cttctctttt tcgttgaata gcaaaataaa tatgatctgt
    18661 caatgtaata tagatatttg aatctaatgg agaggagatc ctagctgtta tcagttcaat
    18721 cacttcttcc gcaaaatcca taaattcgat tggaatctgc gagactatct cactgaatcg
    18781 tttgatcttt tctttagaat ctaatacaaa taatttgtca gcatcctcaa catcaaatgg
    18841 cttactcact ttagcagaaa agccaatccc tttccccatc gcaatttttt ctattccatc
    18901 gtcatcgatc aatacagcat tatgattcag ctttttcatc acatacaccg ttaattcacc
    18961 tcctctatat gataaaacaa aacaacttgc agactccttc atacatattt ttgtctccaa
    19021 acaattttta aagacaaaaa acgacctaag aaagaaccct ttcttaggtc gtgcctaatt
    19081 gaatagtagc accctacata atttacaaaa atagtttaac acataataaa agcgttatca
    19141 atatcttttt tactcgtttt atgataatac ttgtatcgaa ttgatttgga ggtaattaca
    19201 taaaaacaaa aaaaatatag caactctcta taagaaagtt gctatattga taattatacc
    19261 ggcggccggg gtcgaaccgg cacgtcctca acggacactg gattttgagt ccagcgcgtc
    19321 tgccaattcc gccacgccgg caaatttaaa aataataact ggggtagctg gattcgaacc
    19381 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaagg
    19441 gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg ttaaccactt
    19501 cgccacattc gccatcataa aagatgttat ttaatttctc aataaaaaac taagatgaag
    19561 acatcttagt caataccggc ggccggggtc gaaccggcac gccctcaacg ggcactggat
    19621 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa gttgatttat tagtactaag
    19681 gcggtaaccg gatttgaacc ggtgatgaag gttttgcaga cctctgcctt accacttggc
    19741 tataccgcca ttatactatt atcaatctat aaaataaaga ataaattata gaaactgggg
    19801 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
    19861 accccaagaa taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat
    19921 ccggtgcgtt aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac
    19981 actaacggtt ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag
    20041 agtggattcg aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact
    20101 tcgctactcc tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat
    20161 ccgttgctct accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag
    20221 aacgacggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa
    20281 cccctacacc acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct
    20341 gcttgtaagg cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc
    20401 cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca
    20461 acgggccagg taaatttgct acggagagta agggattcga acccttgaga cagtttggca
    20521 ccatctacat gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa
    20581 gaagctcaat actctttctc aaaatgagaa ctccggcagt aggactcgaa cctacgacat
    20641 catgattaac agtcatgcgc tactaccaac tgagctatgc cggaataaca tcagcgtggc
    20701 gacgtcctac tctcacaagg ggcaacccct cactacaatc ggcgctaaga agcttaactt
    20761 ctgtgttcgg catggttaca ggtgtatcct tctcgctatc gccaccacac tgtggtgtta
    20821 tcttttattg agtaaatttt gttcactcaa aactggattt gaagtcacat aagttttttt
    20881 ccgagt
//
LOCUS       DADVXK010000041        20590 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.041, whole genome shotgun sequence.
ACCESSION   DADVXK010000041 DADVXK010000000
VERSION     DADVXK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.041"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="KB909_001456"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="KB909_001456"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBB6837483.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="KB909_001457"
     CDS             1011..2258
                     /locus_tag="KB909_001457"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBB6837484.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="KB909_001458"
     CDS             2334..2678
                     /locus_tag="KB909_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837485.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="KB909_001459"
     CDS             complement(2795..3121)
                     /locus_tag="KB909_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837486.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3736..4938)
                     /locus_tag="KB909_001460"
     CDS             complement(3736..4938)
                     /locus_tag="KB909_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6837487.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5055..5570
                     /locus_tag="KB909_001461"
     CDS             5055..5570
                     /locus_tag="KB909_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6837488.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5769..6215)
                     /locus_tag="KB909_001462"
     CDS             complement(5769..6215)
                     /locus_tag="KB909_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6837489.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="KB909_001463"
     CDS             complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="KB909_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6837490.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8094..8723)
                     /locus_tag="KB909_001464"
     CDS             complement(8094..8723)
                     /locus_tag="KB909_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6837491.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8707..9171)
                     /locus_tag="KB909_001465"
     CDS             complement(8707..9171)
                     /locus_tag="KB909_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6837492.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9658..10926)
                     /locus_tag="KB909_001466"
     CDS             complement(9658..10926)
                     /locus_tag="KB909_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6837493.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11157..11894)
                     /locus_tag="KB909_001467"
     CDS             complement(11157..11894)
                     /locus_tag="KB909_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6837494.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11961..12530)
                     /locus_tag="KB909_001468"
     CDS             complement(11961..12530)
                     /locus_tag="KB909_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6837495.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12658..13530
                     /locus_tag="KB909_001469"
     CDS             12658..13530
                     /locus_tag="KB909_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6837496.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13872..14744
                     /locus_tag="KB909_001470"
     CDS             13872..14744
                     /locus_tag="KB909_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6837497.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14741..16699
                     /locus_tag="KB909_001471"
     CDS             14741..16699
                     /locus_tag="KB909_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6837498.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17031..17882)
                     /locus_tag="KB909_001472"
     CDS             complement(17031..17882)
                     /locus_tag="KB909_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6837499.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18005..18472
                     /locus_tag="KB909_001473"
     CDS             18005..18472
                     /locus_tag="KB909_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6837500.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18735..19217)
                     /locus_tag="KB909_001474"
     CDS             complement(18735..19217)
                     /locus_tag="KB909_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6837501.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19317..20180)
                     /locus_tag="KB909_001475"
     CDS             complement(19317..20180)
                     /locus_tag="KB909_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6837502.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6200 a         4228 c         3724 g         6438 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgat cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca atcagctgac cctcggtatt agctcaaaaa acggtaaaat
     3421 atgagaagct atttttccgt tttgtttctc taatacttag gataaaacgc tgattttaca
     3481 acctctgtta aacggtgttc aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa
     3541 tatgaggaac tatttttccg tttgtttctc taatactcag gacaaaacgc tgattttaca
     3601 acctcctgat aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3661 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3721 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3781 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3841 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3901 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3961 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     4021 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     4081 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     4141 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     4201 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4261 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4321 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4381 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4441 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4501 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4561 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4621 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4681 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4741 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4801 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4861 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4921 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4981 tcaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     5041 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     5101 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     5161 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     5221 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5281 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5341 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5401 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5461 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5521 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5581 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5641 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5701 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5761 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5821 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5881 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5941 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     6001 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     6061 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     6121 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     6181 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6241 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6301 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6361 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6421 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6481 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6541 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6601 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6661 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6721 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6781 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6841 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6901 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6961 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     7021 cagtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     7081 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     7141 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     7201 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7261 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7321 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7381 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7441 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7501 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7561 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7621 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7681 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7741 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7801 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7861 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7921 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7981 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     8041 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     8101 aacatagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     8161 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     8221 aactgatctg cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8281 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8341 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8401 ggcatcttcc ctgattcgta agcttggttg tagatttctt cgccatattc gtaacattgc
     8461 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8521 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8581 ttcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8641 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8701 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8761 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8821 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct tgattttctt
     8881 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8941 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     9001 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     9061 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     9121 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     9181 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9241 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9301 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9361 tattgattct tatcaaacta tagaagatag ctcttctgca gtagataatt ttacaccgcc
     9421 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9481 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9541 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9601 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9661 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9721 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9781 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9841 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9901 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9961 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
    10021 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
    10081 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
    10141 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
    10201 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10261 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10321 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10381 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10441 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10501 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10561 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10621 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10681 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10741 aattgtattt tctgagacag tagctgactg caaagtactt tctgtatcgt tttcaattcc
    10801 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10861 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10921 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10981 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttaa taaatttgct
    11041 ttttctgcat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    11101 ggtcgtttga ataactattt aacaagtaat tctctctgga tattatccgt tatggattat
    11161 acttcctgtg tcgtcggacg gataatcatg ttgctgacag acatccggtc tggcgtttct
    11221 atcgcaaatg ctacagcaga agctatatct tcagatgtta atccccattc tttttgcgct
    11281 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11341 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11401 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11461 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11521 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11581 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11641 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11701 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11761 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11821 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11881 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11941 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    12001 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    12061 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    12121 tttttcttga tgtggattgg ctttactgac aagcctcttc gttcttttgg atcggttaga
    12181 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12241 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12301 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12361 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12421 gctgctaaag gctcttcgtt ttccgcttgg atctgatgga tcacttcaaa gagcggatcc
    12481 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12541 ccttttatcc ttactttata acggacggct tatgatgtct aatacttata aaacatactt
    12601 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12661 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12721 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12781 gaacttggtg tgacactttt cactcgaggc tcccgagaga tacagttgac ggattctggt
    12841 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12901 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12961 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    13021 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    13081 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    13141 caagatcgtt ggggactttt gatacatcgg aatcatcctt tagcaaagca aacagtcatc
    13201 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13261 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13321 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13381 gggatcatca atacttatgg gacggaaaaa gtattcatcc cactcgatcc gccattacaa
    13441 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13501 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13561 ttaacaacga ataagttaag caaaagatcc aatgattaaa taacataagt ttcttaattt
    13621 gttccttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13681 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13741 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13801 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13861 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13921 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13981 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    14041 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    14101 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    14161 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    14221 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14281 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14341 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14401 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14461 cattttcact gaattattca agactggtga atcatttacg actgcttcta caacgaaccc
    14521 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14581 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14641 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14701 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14761 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14821 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14881 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14941 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    15001 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    15061 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    15121 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    15181 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15241 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15301 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15361 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15421 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15481 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15541 aaacaaagca aaaacagctt ccttgatgtt agcagcagct tttgcttcat tctttactgg
    15601 tgtaacagaa ccacttgaat tctcatttat gttcgttgct tggccattat atgtcttgca
    15661 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15721 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15781 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15841 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15901 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15961 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    16021 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    16081 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    16141 cgttgcagat gagatggcaa aactacatgg tggtgctgca acacgacctg cacaaacaaa
    16201 caccgtggtt aaaacagaaa catttgccgg tggaacgatc gaacaagata tttacgctat
    16261 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16321 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16381 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16441 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16501 atatgtaaaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16561 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16621 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16681 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16741 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16801 caactccgcg gtaataagtc cagccaaacg taacatatga agagctattt tttatttgac
    16861 tcttcttatt acttgatgca gaacagcttt tttacaacct ctgataaacg gtgttcaaaa
    16921 accagtttat cggtatgaag tcaaatttat gcaaaaatgt ggaaagccat tttcacaaaa
    16981 tttttcttca tactcaaaac taatcggctt tttcacaacc tctttataca ttattcctga
    17041 tccaatattt cttttaatgc tgcttcaaga gaagttaatg gttttcccaa tactttttct
    17101 aaatcatcag aggaaatagc taactgatcc tttttaatat catgttggat cgctaaaaac
    17161 atgtcagctg cttcttgagg gaatccggct tcttttagat tttcgacaaa cgctgcatca
    17221 cttgcttcaa taatttctaa ctttttacct gtcgcacgct ctaatgcctt ggctaattct
    17281 tcatagtcag ttagattgcc ggataattct aagatttctg gagagtcact ttctactagt
    17341 acttttgctg cagcttctgc atattcacgt ttcaatgccc aacctgtttt tccatttcct
    17401 gcagcataaa cgaattgacc agtttttaaa gcctgcccaa tgataggtaa ttcattctct
    17461 acataccaat tattccgtaa aaatgtatgg gaaatacctg aatccttaat cattttttca
    17521 gtgaattggt gatctggcgc taatacactg atcgagtgat cggcatctgc aaaacttgta
    17581 taagcgatat aagatacccc agctgcttgt gctgccttca ctacattctt atgttcggct
    17641 tgacgatttc ctggaacgcc agagacaaaa agcaatcgat ctattccttt caacgcttct
    17701 ttcattgagt ctaaatcatc ataatcacca atacgtatat taaatccagc ttctttcagt
    17761 gcttctcctt tttcttcact acgtactagt acatagattt cattttgtgg aaccatcttt
    17821 tttaagaatt ccagcgcata accaccaaaa cctccagttg ctcctgttac taaataatgc
    17881 atatttgcca ctccctattc tttttatttg ttaagattta cagctgtaca tttataaatt
    17941 acacctttat cataaagagt gtggtaagat aagtcaagca aaaaaaatga aaggatgaca
    18001 actgatgaag tattctctgc aatttagtga tgcaatccat gtacttgcct atattgaaat
    18061 gtttcaagat acccgatcac tttctagtga gatgattgcc agtagtatcg aaacaaatgc
    18121 agcaaatgta cgtaaaatca tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac
    18181 cggaaaaccg cagccttccc ttgccaaaag tccagatcag atttctttac tagatgtcta
    18241 tcgcagcatc gaaggtaata cacagcttat ccaagtcgat ccaaaaacaa atccaaattg
    18301 cgtcgttggt gcgaatatcc aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa
    18361 ggcagaagaa gaaatggcta agatcacact tgatagtctg atacataaaa tagccgtttt
    18421 ggaaaaagaa aaaagaccag aaaacacagg cctcgtagag agatttttat aattctctct
    18481 actgtgcctg catttttctg atcggaatcg tctacataaa ttcttttatt ctccggggga
    18541 caaaagcctt gtcatgcccc tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat
    18601 gacgtcttga taaacggtgt tcaagtagct gaccctcggc attagttctg aaaaatgcaa
    18661 aatatggaaa gctatttccc atttttcctc tctaatgctc aggtcaaagc gctactttca
    18721 cgacctctat attatcatgg tttattgact accggtatcc agatttctcc catatatttc
    18781 ccgttggtaa ctcccatttc gactacagca tttggacccc caacataggc gtaatcttct
    18841 acttctctta aaacatgccc aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc
    18901 gattctgcta aagcgattac aacaagatac gttccttttg ggaatgggat gattcgggta
    18961 gtgtttggaa catcctgact cgtttgaaca ccgacatagt acatcatttt cccgttatag
    19021 ggttcgttga ctgtaaagaa ataatgattt tcagcagctt gtttcaatgc atctattgtt
    19081 ccattaccga taactttttg ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc
    19141 gtattgctac tcttcaattc cacaccaata cccgtcaccg taaaatctgg tttttcttcg
    19201 atcctatact ttgccatttc tcccaccctt tctattatat taagttcatc ttacataaaa
    19261 ttaaagggaa atgacacgat tacgctcttt tttctaggga tatttttatt ttttaactat
    19321 ttttttgctt tcactgcaat ccaaatctca ctgtaaacat tactgaaatc ctctccccat
    19381 tttgtaaaag agatctcggg agcttcgact aactcataat ctgaagaagg aagccattct
    19441 gcatagattt tcccccaagt atcttgtaaa gtttggggaa atggcccttt attaggaaaa
    19501 atggcccaag tgtgttcttc tatagcaagc atttctaaat cagcgtacgg attttctttt
    19561 gtcgtagcaa agccaatcat gtgcatcaaa ctgccctttt cttccaagcg ggctccatca
    19621 aatccataag aaacgttgat tacttgattt ggatataaat ctcctaactt atgcatctct
    19681 tccctttgag tctccgtgat cgtctgcgct aacttttgta tttcttgatt gactccttca
    19741 aatttgacag gaactttttt cgccacacct gccacataaa actgttcttt cttttcgata
    19801 cgaaattcca tcgattttcc tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat
    19861 ttttgtatgc cgtatctgct gatttctgaa ggcagatatc ctgaccaatc acgaaaagct
    19921 cttgaaaaac cttcgactgt ttcatatcca tatctaaacg ccgtttctgt cactcttgat
    19981 ccatctagga gatcgcgatt agccaaagcc aatctacggt ttttgatata gtccattagc
    20041 gacatccctg caataaacgt aaagatgcgt tttaattgat attcagagat tcctgtattt
    20101 tcggctatta ttttatagga aagtccttct gtcaaatgtt cttcgatgta atcgatcaat
    20161 tggttcagat ctttaagcat atttatcttc ctccttgctt gcctttttat catattatca
    20221 aagaaagtca attacttgat gaatcaggaa ccaatttagt cagatgtaga aaatgttgta
    20281 tggatctaaa gaaaattctc aagcagcgtt tcgtaacgga taattggtat tatctgccta
    20341 tctatgtttt acctttagaa aaataaattt tggggaagac acattctaag taaacaaagc
    20401 ggtaaaaata tcttttattc ccttagttaa tccgcttact acctactgta caaagcaaat
    20461 tgttgttcaa actgctgatc agaacgctgc ttggattttt ctttgcgata catcatacct
    20521 cttttatcaa ttggaacaat tatttatttc taacaaaatc acttcatttt tgtcagataa
    20581 ataaaaaaca
//
LOCUS       DADVXK010000042        20501 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.042, whole genome shotgun sequence.
ACCESSION   DADVXK010000042 DADVXK010000000
VERSION     DADVXK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.042"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(31..1170)
                     /locus_tag="KB909_001476"
     CDS             complement(31..1170)
                     /locus_tag="KB909_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBB6837503.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1569..2867)
                     /gene="eno"
                     /locus_tag="KB909_001477"
     CDS             complement(1569..2867)
                     /gene="eno"
                     /locus_tag="KB909_001477"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBB6837504.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2983..3738)
                     /locus_tag="KB909_001478"
     CDS             complement(2983..3738)
                     /locus_tag="KB909_001478"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBB6837505.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3842..5032)
                     /locus_tag="KB909_001479"
     CDS             complement(3842..5032)
                     /locus_tag="KB909_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBB6837506.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5142..6143)
                     /gene="gap"
                     /locus_tag="KB909_001480"
     CDS             complement(5142..6143)
                     /gene="gap"
                     /locus_tag="KB909_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6837507.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6184..7275)
                     /locus_tag="KB909_001481"
     CDS             complement(6184..7275)
                     /locus_tag="KB909_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBB6837508.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7424..8758)
                     /gene="rpoN"
                     /locus_tag="KB909_001482"
     CDS             complement(7424..8758)
                     /gene="rpoN"
                     /locus_tag="KB909_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBB6837509.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8818..8889
                     /locus_tag="KB909_001483"
     tRNA            8818..8889
                     /locus_tag="KB909_001483"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8851..8853,aa:Arg,seq:ccg)
     gene            complement(9081..9965)
                     /locus_tag="KB909_001484"
     CDS             complement(9081..9965)
                     /locus_tag="KB909_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6837510.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(10052..10951)
                     /locus_tag="KB909_001485"
     CDS             complement(10052..10951)
                     /locus_tag="KB909_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBB6837511.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(10968..11474)
                     /locus_tag="KB909_001486"
     CDS             complement(10968..11474)
                     /locus_tag="KB909_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBB6837512.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(11663..12283)
                     /locus_tag="KB909_001487"
     CDS             complement(11663..12283)
                     /locus_tag="KB909_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBB6837513.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(12359..12796)
                     /locus_tag="KB909_001488"
     CDS             complement(12359..12796)
                     /locus_tag="KB909_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBB6837514.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            12959..13789
                     /locus_tag="KB909_001489"
     CDS             12959..13789
                     /locus_tag="KB909_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBB6837515.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            13773..15140
                     /locus_tag="KB909_001490"
     CDS             13773..15140
                     /locus_tag="KB909_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6837516.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            15159..15968
                     /gene="yidA"
                     /locus_tag="KB909_001491"
     CDS             15159..15968
                     /gene="yidA"
                     /locus_tag="KB909_001491"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBB6837517.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNNEHGVAEAIKKYVL"
     gene            complement(16011..16454)
                     /locus_tag="KB909_001492"
     CDS             complement(16011..16454)
                     /locus_tag="KB909_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBB6837518.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            16588..16959
                     /locus_tag="KB909_001493"
     CDS             16588..16959
                     /locus_tag="KB909_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6837519.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            complement(17128..17910)
                     /locus_tag="KB909_001494"
     CDS             complement(17128..17910)
                     /locus_tag="KB909_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBB6837520.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(17907..18878)
                     /locus_tag="KB909_001495"
     CDS             complement(17907..18878)
                     /locus_tag="KB909_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBB6837521.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            18970..20364
                     /locus_tag="KB909_001496"
     CDS             18970..20364
                     /locus_tag="KB909_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6837522.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
BASE COUNT         5767 a         4229 c         3653 g         6852 t
ORIGIN      
        1 ggctctgttt tttcatttat taaaaaaatc ttacgctaag taggataaaa taattccttg
       61 atatttttcg atcatatcca aataattatc gatttcaaca tactcatcta cttgatgagg
      121 caaagtaacg acaccaggcc caaagacgac aaagtcgaag gaatggttag ctttcgtaaa
      181 ttcggctgca tccgttgttg ctgccgctcc aactaaaggt aatggctggc tgaattgttg
      241 ctgaatgcaa tgaatcaaag gagaatctgg atcagctttg acaggtattt tgttgtaatc
      301 gatcatcaat tccaaatgat agtctgtctc ttgattcaat tcattgacga ttgattgcag
      361 caatgcaatg attttatcat ttgggtattc tggaatcgat cgaatgttcc cttggagctg
      421 cgcatggctt gggatgctgt tgacttgatt cccgccactg atcaatgtaa cattatggat
      481 tgtttttcct aggacaggat tctcgattgt ttcagcgagg tgattcattt cagcatttgc
      541 tttcgtaatg aattcattta ggtgattgat tgcattataa ccttggtctg gcatagagct
      601 atgcgcttct tttccgtgcg aggtgactgt atagttgatt gatcccatgt gcgtatacat
      661 caaactgtaa ttggttggct ctccgatgat caaggcatct aagtcatcta catagcctgc
      721 tttcgtgagc tgttccccac ctagttcacc cacttcttct ccgacagtgg ctaataattt
      781 gactgttccg ttaaatggtt ttcctgactc tttcagttcg atcatggcaa tcaccattgc
      841 tgccaagcca ctcttcatat ctgtagcacc acgtccgtac aaacggttcc catggatttc
      901 tgctgcaaag ggtgcatagg tccaagacga ttcatcacca gccgccacga catccatatg
      961 cccagatagg cctaacactt ttcctgattg gcccttttgg taacgagcaa tcaaattatc
     1021 tctaccatct ctgtaagaaa caatctctcc tgttatgtca tgctttgcca aaagcttatt
     1081 caaataggct gctacttcac cttcgtttcc attcactgat ttaattcgga tgatctcttg
     1141 taaaatcgcg attttttctt cttttttcat ctaatcctct cccttgccat ttctttttat
     1201 tgtatttgag tgtgctcgaa ttttcaaata ggagcaacca aagtaaaaat gaagaaagag
     1261 agccacttta tgaaaaatat gctgctactt ccctcctatt ttatttatac gagaggactt
     1321 gctcatagat tcctattcta ctgttctatc cttaaaagct cttatatgat gctagttatt
     1381 gttagctttc ctttttcaag gatgatcttt tcttgtacca ttctttgtaa acatcatata
     1441 cagaagctag ttgcaaaaaa actctctacc tgctgatatt tcagcaagta gagagttcga
     1501 ttacttaact aagtgatcat actcgactat ctttcaatag tcgatcatgt atcttcatta
     1561 gaaaagaatt atttgttttt taagttgtag aaagatttca aacctttgta ttctgcaact
     1621 tcaccaagtt ggtcttcgat acgtagtaat tggttgtatt tagcaatacg gtcagtacgt
     1681 gatagagaac cagttttgat ttggccagcg tttgttgcaa cagcgatatc agagattgtt
     1741 gaatcttctg tttcaccaga acggtgagat acaactgctg tgtagccagc ttctttagcc
     1801 atttcgatag cttcgaaagt ttctgttaat gtaccgattt ggttcacttt gataaggatt
     1861 gagttagcaa ttcctttttc gataccttca gataattttt gagtgtttgt tacgaacaag
     1921 tcgtcaccaa ctaattgaac tttgtcgcct aatacgtcag ttaatttctt gaatccgtcc
     1981 cagtcgtttt cgtctaatcc gtcttcgatt gagatgattg gatatttaga aactaattct
     2041 tcgtagaatt tgatcatttc gtcagttgtt ttttcgcctt cgcctgaatc agctagtacg
     2101 taaacacctt tttctttgtc gtagaattct gaagaagcag catccatagc aagaacaacg
     2161 tctttaccag gtacatagcc agctttttcg attgcttcga tgattacttc aaaaccttct
     2221 tcgtttgaac caaggtttgg agcaaatcca ccttcgtcac caacagaagt tgctaatccg
     2281 cgagctttca agattgaagc taatgcgtgg aatacttcag cacccatacg tagagcttct
     2341 ttgaatgttg gagcgccaac aggcatgatc atgaattctt ggaagtcgat tgagttatca
     2401 gcatgtgatc cgccgttgat gatgttcatc attggtgttg gcaatacttt tgtgttgaat
     2461 ccgcctaggt agtggtataa aggtacttct aggtagtcag cagctgcacg tgcaacagcg
     2521 atagaaacac ctaaaatagc gttcgcacct aatttacctt tgttaggagt tccgtctaaa
     2581 gcgatcatag ctttgtcgat agccatttgg tcacgaacat cgtagccaat gattgcttca
     2641 gcaatgatgt tgtttacgtt gtcgacagct ttagttacac ctttaccgcc ataacgagct
     2701 ttgtctccgt cacgtaattc aactgcttcg tattcaccag ttgaagcacc tgaaggaacc
     2761 attccgcggc caaaagctcc gctttctgtg tatacttcta cttcgattgt tgggttacca
     2821 cgtgagtcta agatctcgcg agcgtaaaca tcagtaataa ttgacatgtt ttgtctctcc
     2881 tttgagtttg ttttttccta agggatttcc ctcatatacg attttagtta attttgctca
     2941 ttagtgcaaa catttcttgc atttttcgca aattttcaac aattatttta cagcgtctaa
     3001 caatgacaag aatgaatctg cttgcaagct tgcgccaccg actaaagcac cgtcaacatt
     3061 ttcttttgcc atgtattcag caatattttc tggttttaca gaaccgccgt attggatacg
     3121 aactgcttct gatacttctt ttccataaag tttttcaact gtttgacgta caactccaca
     3181 aatttcgtca gcgatttgtg cgtcagctga tttaccagta ccgattgccc agattggttc
     3241 ataagcaata accatgtttg acacctgttc agctgaaaga tcagctaaac cagctgtaat
     3301 ttgtccttcg atccattcag cagttttgcc tgcttcatag gtttctaaag attcgccaca
     3361 gcataggatt ggtgtcatac catttgcaaa gatagctttc gcttttttat tgatgtcttc
     3421 gtctgtttca tggaaatatt cacgacgttc tgaatgtccg atgatcacat aatgaacacc
     3481 tagatcagca agagctgctg gtgaagtttc accagtgaac gcacctgagt tttcccagta
     3541 gcagttttgt gctgagattt ttagttctgt accttcagct gatgtcatta attcttgtaa
     3601 gaataatgca ggagatccga tgactgaatc aactttgtca tttgaaggga ttttgttttt
     3661 tactgcttca gcaaattctt ttgcttctga tgcagttttg ttcattttcc agttacctgc
     3721 gataataggt ttacgcattg aggaacacac tccttaattt attgaaaaat ggctagggag
     3781 tcatgaaaac tcccttcacc ttttgttcga ttactcgtca gaattgagca aacttggtcg
     3841 tttatttatc gttgattgct gctagtcctg gtaattcttt accttcaagc aattccaagc
     3901 ttgcgccgcc acctgttgag atgtgtgtga atttgtcagc aaatcctaat tgttctgctg
     3961 ctgcggctga gtctccgcca ccgatgattg ttgttgcgcc ttctaagtta gcgattgctt
     4021 cacaaacacc gattgtacct ttagcaaagt tactcatttc aaatacaccc ataggtccgt
     4081 tccaaacaac tgtttttgca ccttgtaatg tatcagcaaa taattttact gatgctgggc
     4141 cgatgtctaa agccatcaaa ccatcaggaa tgtctccttc gattacttgt gtttcaacat
     4201 catttgaaaa ttctggtgca cagacattgt cgattggcaa gacaagtttg tcgcctgctt
     4261 tttcgattaa ttcttttgct agttccactt tatcagcttc tactagagag ttaccgatct
     4321 tgattccttt tgcttcgtag aatgtgtaag tcattccgcc accgatcaag attttatctg
     4381 ctttaggaat caagttttcg attacgccga ttttatcaga aacttttgcg ccaccaagga
     4441 ttgcaatcat tggtcgtttt ggttcttcta ctgcttcacc gatgaacttg atttcttttt
     4501 ccatcaagaa tccagcaact gttgggatac cagttgaagc gatacctacg ttagaagcat
     4561 gtgcacggtg agctgtaccg aaagcatcgt taacaaatac atcgcctaat gaagcccagt
     4621 atttacctag ttctgtatca tttttgcttt cttttttacc gtcaatatct tcaaatcgtg
     4681 tattttcgaa tacgacaacg tcgccgtcat tcatgttgcg gattgcttct tctaattgtt
     4741 ctccgcgagt ttcaggtacg aatgttactt ctttacctaa taattcgcct agacgttttg
     4801 caactggagc taaagatttt ccttctttat cttcttctgt ttttacacgt ccaaggtgag
     4861 agaaaaggat tgcttttccg ccttgttcta gaacgtagtt gattgttggc aatgctgctt
     4921 tgatacgagt gtcgtcagtg atcacgccgt ctttcaaagg aacgttgaag tcaacacgga
     4981 caagaacttt tttgtctttt aaatcgatat ctttcactgt tttcttagcc attttatttc
     5041 ctcctgaata aacttattat caaaaaaagc ggaagaagcg cgattgcttc cccgctttta
     5101 aatgtacatg tctataattt acacttgtac gtttgtctat cttataagtt agcgaagtat
     5161 tctaaagtac gtactaattg tgcagtgtat gacatttcgt tgtcgtacca agcaacagtt
     5221 ttaactaatt gtttgtcgcc aactgtcatt actttagttt gtgtagcatc aaataatgaa
     5281 ccgtaagtca taccaacgat atctgaagaa acgatttcgt ctgtgttgta tccgtaagat
     5341 tcgtttgaag cttctttcat tgctgcattg atttcgtcaa cagttacttc tttttcaaga
     5401 actgttacta attctgttaa tgaacctgtt ggtacaggaa cacgttgagc agctccgtct
     5461 aatttaccgt tcaattcagg aattactaaa ccgatagctt tagcagcacc tgttgagtta
     5521 ggaacgatgt ttgcagcagc agcgcgtgca cggcggaagt cacctttagg atgaggtccg
     5581 tctagagtca tttggtcacc tgtgtaagcg tggatagttg tcattaatcc ttcaacaaca
     5641 ccaaatttgt cgttcaatgt tttagccata ggagctaaac agttagtagt acatgaagca
     5701 cctgagataa ctgtttcttt accagttaat gtttcgtggt ttgtgttata aacgattgtt
     5761 ggaacatcgt ttccgccagg agcagagata acaacgcgtt tagcaccagc tgttaaatgt
     5821 ttttcagctg ctgatttaga agtgaagaaa ccagtacatt ctagaacgat atctacgcct
     5881 agttcgcccc atggtaattc ttctgggttg cggttagcta atactttaac ttcttttccg
     5941 tttacgttga atgaaccttc atgaacttca actgttccgt tgaaacgtcc ttgagttgtg
     6001 tcgtatttta acaagtgtgc caacatttta gcatctgtca agtcgttgat tgctactact
     6061 tcgattccat ctacatcttg gatacgacgg aatgctagac gtccaatacg tccaaaacca
     6121 ttaataccta ctttaactgt catttaagat ttcctcctta tgaaaatcaa aaaaatattt
     6181 attttaaagg gttacccctt ttaaaatctc atttgcagca gcttcatcag tgatgagcca
     6241 cgtttgtttt ggtgcatttt tcatataagc tcgaattgct ttagcttttg attttccgcc
     6301 cgcgattgcc atgatgatcg ggactttttc caaatcttgc aattctatgc cgattctagg
     6361 gaccttataa acgacttcac ctttttcatt gaaaaagtag ccaaaagatt ccgcaacagc
     6421 atttgcttgt ttcagcatga ctaattcttt ttcagtcatc ttacgacgtg ctgccatgtg
     6481 taatgcacgc ccaatactat gaataacaca attcgcttca ctaatcaagt ttaagacttc
     6541 ttggatagat ggctcattga gtaaagaatt gtaagttgcc agacttaatt gttccggaac
     6601 ataaagtgca cggtggttac cgtttgcttt agcagccatt cttgcactga cagaatttgc
     6661 ctgtacagtt atcgcttcac caatcccgcc tcttgcaggg acaaacaggt tatgccgttt
     6721 cttattttcc agattagaca attgttcggc taccacagcc atagtagttc ctcccatcac
     6781 agcgatgata ttctcgcctt ctggaagtag tcggtctagg gcttcgctca gcgcttcgcc
     6841 gaatgcatca gccactttgg tctgctcttc gctgtttcct gaaacaacga tacagcgttg
     6901 gttaccaaaa tattctgcca actgttgttc ggtttgatgc gtacctaaaa gctgatccat
     6961 gaagttttca aggctttgat aaacttcttc gcccttagtt gtcagcgtca taccgctttt
     7021 tgaggtgtcg atcaaattca gatttttcaa aagatctgtt tctgttcgca atactcgttc
     7081 tgtgatcccc atactttccg ataaacttcg acgtccaatc ggctgcatcc aatagatatt
     7141 tcgtaaaatt ttatagcgtt cttgcaacac ttcgataata tctggtgcaa cagattcaat
     7201 catttttatt tcatccagca tagcgatctc cttagttgga cactttacgt ccaatgtaga
     7261 cttaaaacga cccatatacg ataaaaaaag aaattaacta ttcgaatttc acatcaataa
     7321 agggaaatct caacctcacg actgtaagtc taacagtttt gctctcgttt ttcaactaaa
     7381 aagactagaa aaagtgaaat actttttcta gtcttttgac tgattagtta tcataacgtt
     7441 ttctttttga tgaactcggg attcctaata aatcacgata ttttgctact gttcgtcttg
     7501 agatcgctat ctcatctttt ttcagcaatt caaccaattt ctggtcagac aacggcttgt
     7561 ttttgtcttc ttgatcgact aattcctgca gctttttctt cgctgtatct gctgaaaggt
     7621 cttctgtctg ttctgtacta ttcgtaggaa ttcgtgtagt gaaaaatttt tttaattcaa
     7681 atacaccgaa gtctgtttcc aaatatttcc cgttgactgc acgactgacc gtggattcat
     7741 gcacatctat ctcagttgca acttccttta acgtaagagg cttgattgga cgttccttgt
     7801 cgataaagaa agctttttgc cgggaaacaa tgacttgagc aacccgcaaa attgtatccc
     7861 cacgttgtag gatcgttttc ttcaaccatt cgaattcctg tttccgttct tttaaataat
     7921 tttcagtttc tttatctgct tgttgtgaca tttgtttgaa gtaactctct tgaaagcgta
     7981 tatttggctg attttttcgg tttgagataa cttgtacatt tttatcgtcg tccactaata
     8041 cccggacatc aggaataatg tacaattcgc tgctacggtc gaaaatccgg ccagggcttg
     8101 gactcaacgt ttgtaaatag tcgaatatct gctgaacagc atgtagatca acagaaaaac
     8161 gttgtgcgat ttctttccat tttcgctcca ccagttcctc aaaacattct tccaacacga
     8221 tataagctaa ttccggcgca taatcatctc gttctgtttg aagcatgaga cattcttgca
     8281 aactacgtgc acctactcca gctggttcta attgctgaat cagagtcaac gcatcgagca
     8341 tttggatagg cgtagctcca atctcttttc cggcttcttc taaactaatc gtcaaaaatc
     8401 cgttcaaatc gatgtattct acaagataaa gaacgatttt cctcaaaaaa gtatctcggt
     8461 aattcaaatg gacttgttcg atcaatgaat caaataaaga cccttttgta tcaggaatct
     8521 gatttaggta atttgtctct tctccttcat aagaagatga agaagctttt atgtaatctg
     8581 gctgccattc cggctcaaca acttccacca atggattttc cattgcttga ttctcaacga
     8641 atgccaacag ctcctcactg ttatattgta aaacttggat ggactgttgc aactgttgcg
     8701 tcatggctag tttctgtgtc tgctgctgtt tttgtgaaaa attttgctca aatttcattt
     8761 ttttgtccaa tccccttgta attttttatc tgtttagtta caattatccc agtgcttgcg
     8821 tccttagtgt agtggatatc acgtaagatt ccggttcttg agacgggggt tcgattccct
     8881 caggacgcgt tctactgcta ttttagcata atttacgaat agttgcttct ttatttttaa
     8941 gtgaaaactg tccgccaaag aaaattggtg gacagttttt tgttgtacct gtatagatat
     9001 tgttaagcct ttgcaagtaa ggtagttatg tgttcaacta cttattaaaa tgtgttattt
     9061 attaaagata cttgtctcac ttactgaact ggccgatgat cgtttctgcc ataatagttc
     9121 tcgacagccg ttggatgccc taataaatcc ccaactgtcg tgatgcgata cccttgctct
     9181 ttcagataat cgatcacttg aggaacggca cgaatcgttt caggatagat atcatggaat
     9241 aaaataattg ccccatcgta tactgttgct tggatcttct gcaaaatcaa atcaggattt
     9301 cttgtcttcc aatcttctga atcaacagac cattcgatga tcggtcgctg gatgatcgtt
     9361 gctcctacat tcgtgacaga accatagggc ggacgaacaa aagtgggggt tttgccagtg
     9421 acttttttga tctcagtgtc tgctttcgtc acttcctccg tcatcgactg ggcagaaaga
     9481 gtggccagat tctgatgatc gtatgtgtga ttgccaatct cgtgccctgc ttcagctgtc
     9541 tgcttcacga tttcaggatg ctgcgccgta ttttctccta agacgaaaaa agtggcatgc
     9601 acgttttttt cttttaagat tcgcagaagc tgcggtgttg tggtcgctcc tggtccatca
     9661 tcaaagctga ttgcgacgct tttgacagcc ggatctcggc tcgtttttgt actgtcttgt
     9721 gttgattgtg atgactgact ttgtaccttt tccgctgatt cttgaatggc ttctttgacg
     9781 ttagctgttt cagttgattg gcttttaatg gttgattgtt ctgattgttt gaaagattgt
     9841 gacgaatgct ccgaagagtg tgtttgtcct tttacttcgg tgatcaagga ggccaccgaa
     9901 gtaatttcga aaaacaaaag cacggataaa gcaataatac tgataactaa ataatttctt
     9961 ttcactatat ctcttctttc tctttttctc ttcttattat ttacttgtac ttacttgaaa
    10021 attgaaactg ctagtcgcaa ctacttctcg tctaatgatc caaataatct tccgatgcca
    10081 aaatcgtttt tgtcacggac ttaggaatga caaattctgg tgtacccata taaccaggag
    10141 caatttcgta ttgagaaaaa gtcaaaacta attgatgctc tttgttcaaa taaaaacttc
    10201 gtgtaggcgt aacaagtgtt ggtttttcta tcgtcccttc ttgaatatct tgctcagtcc
    10261 aatagtactt agatggatct tccttgactt gttcggccat ctgccgtttg acttcttttg
    10321 tcaaaacaga tagataggtg tcatctttga ataaaagtgg aagtgagagc tggacactgt
    10381 ttttcttgtc gattgtgtcg tatctttttt caacatggct atctgctgct gtttgggtga
    10441 tctgcctttc aatcacgaga aaccggttat cgtctacgat tttctgataa tctcccaaaa
    10501 cttggtaatg atccgtttca aaatttccat attctttttc agctttttca aaatctgctt
    10561 gtccttcgcg aaagtatttt tgatttaatc catgaattgt tttattttct ttctcatttt
    10621 gtgtattgat cttcggtacc tgaatatcga ttttttcaga tcgatcagta aagcgttcgc
    10681 ctaagatcaa ttcaatgact gatcctaaga tgggtaaatc ttctgcaaag cttcgaactt
    10741 gactattaaa aagaaggcta cttgttgtaa tcattacgat agccaaagat actccgaacc
    10801 cttggagacg tctctttctc cgctttgctt ttataaatga ttgctcttcg ataataaaac
    10861 gctggcggat ctcctcttta agccctttgg gaattgcttg ttctttataa gttttcttta
    10921 gtttttttaa attttctttt tgggaataca tggcactctt ctctccttca ttctaggatt
    10981 tgacgtaaag cattcaatga gcggtacatt ttcgttttaa ctgtgttttc attcatatcc
    11041 aagatagtcg caatttcttt caaacgaaat ccttcaaaaa agtagaggat cagaatctct
    11101 ttttccggac tgtctatttt atctaaaatc atatggagct ctgcaacgga agtttctaaa
    11161 ggtaactgtt gggggatatc ttgaatttca aataagtcca caggcgtcct tttttgtctg
    11221 cgccaactat ctaatgccgt gcggatcaat atccgataaa accatgcact aaaatgctcg
    11281 atctcttttt ctttttcaaa atagttcagg gctttatgaa aactatcttg catcacatct
    11341 aaggcctctt ctttatcatg tacgtaattc atcgtgatac ggaacatttt ttgataatca
    11401 gtttcgatga gtccattcag caggtgacgg tatttttcga tctgccgttt tttcttatat
    11461 ccagtaaaaa tcattctcca ctcctttctg cctcacttaa tatgacgtac aaggtgcgct
    11521 aaaagtttca atttttttat tttttatgta tttacttggg atttttatat acaaaaaaga
    11581 aggtgtgaca aaaatcgtgt cacacctcct tattctgata ggctgatcgt ctctgtcaca
    11641 acctctcgta agaaaataat gtttattctt tttcagagtc agaaaattct tcctcttcat
    11701 aatcttcatc atcatcgtct tcgtctatga tacttaaatc ttcttcgata tttcctggca
    11761 agtcttcttc atcatctgtc gggtcatctg ctccgatttc ttgcaagtca gaattataag
    11821 cagcgatttc ttcatcttca tcatcatcgt catcaaacag atcatcgtca tcttcttctg
    11881 tcagatctgt atcttctggg tcatcgtcat tgtaatcgat cgcgtcttca tcatcattga
    11941 taaaggcgtt gactttcttg cgtttacggc gacgtggagt atcttcatcc tcttcgtcca
    12001 ttccatggtt tacttcttca tcgatcgaat cgatagcata ccatgaacgc aagccccaac
    12061 gattatcccc taatgagata aagctgccgt caatattcaa gtcagtataa aattgtgcga
    12121 gtgaatcacg aatttcactg tctgatttcc caagatagtt ttggatctgg ttagctaaat
    12181 cagaaaaatc catgacatcg ccacgttgtt ctaagatcgc gtgtgctact tcgatcattg
    12241 ataattcgct tttgtttgca ccttcaaata cactaatttc caatcaggac acgtcctttc
    12301 acagtctact ccttatcata caaaatcaga cacaaaaaat caaacttttc ttttatattt
    12361 acgctgtaaa atccaaggtc aaataatatt cgccgatttt ttccggtccc atgaacagat
    12421 cataatcgat tcgaaccttc cctgctgtgg gacggtcttt caaactaaca tgcagttctt
    12481 tcgtaaaagt agcaatctgg atcataccgt atggtgttcg ataggatgtt tctaaccgtt
    12541 ctttatagcc aaatttcaaa cgcatccgca tttctcctgc acggatcagc tgtacatgac
    12601 catctggaac taatttgatc gttacaggaa tctcatcgcc cgtctcctcc tgaatctctt
    12661 tataacgtat gtacagcgta tcgccaattg tcaccatttg ccctttcaaa tcaaaataaa
    12721 aatcttgcac ttccccttgc tgttttactt ttgtacgcaa tttgattgaa atcggtgttc
    12781 cttgtgataa ttccattatt cattctcctt tacttctcat agctacattg ttcctagttt
    12841 cttttgtttt gtcaaccaac ttgtccattt ttacagaaaa ccttttttcc aaaacaactc
    12901 tttgatttta gagtataata ttgtagaaaa tatgaattta tacaaaggag ccggttgaat
    12961 gaaccctgcg attcgactag atcagcacat ttatcaaaaa aacgactttt ccccttttgc
    13021 attaacagat atattaacgg aatattctaa agaacaccag caaatctttt tacatttctg
    13081 gcaatatgac tgcacagtca tcttaggtat gaaggatgtt cgaactcctt ttctaagtga
    13141 cgggatccaa acactgaaag atgcaggtta cgctccagtg atcagaaatt caggtggatt
    13201 agggatcgta tcagatgaag gaattttgaa tatttctttg attttccccc aaagtgacac
    13261 aaaaaaaata accatagatg acgcttacga gcaaatgctc ctattgacta aatacgcttt
    13321 tccaaaggca ccgatacaag cattcgaaat cacccattct tattgtcctg gaacttatga
    13381 tttaagcatc catggcaaaa aatttgccgg tatcgctcag cgtcggatca aaaatgggat
    13441 ttctgttatg atgtacttaa gtgtcaacgg taatcaggaa aaacgcgggc aagtcatgaa
    13501 gcgattttat caatctgctt taaaagaaga ctttggtaca aatggctatc ctgcagtgga
    13561 tcctgctaca atggcaacac ttgaagaact gcttgaccaa cccctttttg taaaagaagt
    13621 caaagaagca tttgcaaaag cttttgaaaa gctgtattct gcaagtgatt tacaggattc
    13681 taccgactgg ctaaaaaaag aaatccagct ggagcaatgg aacaaccaaa tccagagaat
    13741 ggaacaacgt aataacataa aggagctaca ttatgacaac cccttataaa tatcaaatgc
    13801 tgcctatgga aaaagttttt cgtgatccag tccataacta tatccatgtc cagcatcaag
    13861 taatcttaga tttgatcaat tcgaaagaag tccaacgtct acgacgcatt aaacaattag
    13921 gcacttcttc tttcactttt cacggagcag aacatagccg ttttactcat tcattaggcg
    13981 tttatgagat ttcaagacga atctgcgata tcttttctcg aaatttttca aaagaaaaaa
    14041 taggcaacgg aggctgggat gatcaggaac ggctggtgac tttatgtgcg gcactgttgc
    14101 atgatgtcgg tcatggtcct tactctcata catttgaaca tatcttccat acgaatcatg
    14161 aagccatcac tgtagagatc atcacttctc cagaaacaga agtgtatcag attcttaacc
    14221 gagtagaaga aggttttcct gaaaaggtag ctagtgtgat ccaaaaaact taccccaacc
    14281 cacaagttgt ccaaatgatt tctagtcaga tcgatgcaga tcgaatggac tatttgcttc
    14341 gggatgctta tttcactgga acagaatatg gaacatttga tcttacccga atattacgtg
    14401 tgattcgtcc ttatgaaggc gggatcgctt tttccatgag tggcatgcat gcagtggaag
    14461 attatatcgt tagccgatat caaatgtatg tgcaagtgta cttccatcct gtttcccgtg
    14521 gtatggaagt aattttggag catctgcttc atcgcgcaca cgagttgtat caagaagatg
    14581 ccagcagttt tgaactccat tctcaattac ttctgccatt tcttgacgga agctttactt
    14641 tagaagaata cctcaaactt gatgatgggg tcttgggcac ttactttact caatggtctg
    14701 aatctgctga tcctatttta aatgatttag ctaaacgttt tttgaatcgt aaaccactga
    14761 aatctgctac tttttctggc aaccgggatt caaaattagt ccaagaactc actttgttag
    14821 tagaaaaggt cggatataat cctgtttatt acactgctgt gaattctagc tacgatctac
    14881 cttatgattt ttatcgccca gaacaaggca gacatcgcac acaaatcgag attttgcgaa
    14941 atgacggaac tttgatagaa ttatcacagg ttagtcagct tgttgctgca ttagcgggac
    15001 aagaacaagg agatgagcga tttttctttc caaaagaaat ggttgatccg tccttgcgtg
    15061 atcattatga tttatttgac gaaacttatc aagaatttgc cagccatatc cgtaatggcg
    15121 cattgattga aataaattaa aatatattgg aggaaattat gtctatcaaa ctagtcgcta
    15181 tcgacatcga tggtacttta ttaaatgaga aaagagaagt aacaaaagaa gtaaaagaag
    15241 cgattgccgc tgctgttgca aaaggtgttt cgatcgtttt atgcactggc cgtcccttac
    15301 caggtgtcca ggaacagtta aacgagttga acctttttca agataatgat tacgttatta
    15361 cttataacgg ggcactcgta caacaaacga aatcaggtaa aatcatcgcc cgtcacggac
    15421 tgacacatga agatttccta gagatcgaag tgatggcacg ccgtgtcggc agtcatctcc
    15481 attcgatcga tgacaaagcg atctacacgc ctaatcgaga tatcagcgct tatacgatcc
    15541 acgaagcaag tttagtcaag atgccgctaa aatatcgaac acctgaagaa atgacaccag
    15601 acatgaacat cgtcaaaatg atgatgatcg acgaaccaga aattttagat gcagcaattg
    15661 cgcgtttacc gcaaactttc cgtgataaat acacaacggt caaaagtgcg ccctattact
    15721 tcgaagtact aaataaagaa gcaagtaaag gtgcggcagt tgcgaatctc gcacagcacc
    15781 ttggtattga tcaagatgaa atcatggcta tcggagataa cgagaacgac ttatccatga
    15841 ttgaatatgc tggtctagga gtagcaatgg gaaatgccgt ttctcttgtc aaagaagcag
    15901 caaatgtcat cacttcatca aacaacgagc acggtgtagc tgaagcaatc aaaaaatatg
    15961 tactgtaata aataaaaaaa ctgagagaaa gctgatctac tcgctttctt tcagttttta
    16021 tttttttcga tccatctctc gactgcccat cggtggctac cacgtttcaa tttcacaagc
    16081 gcttcttgag ggctcaccca ccaaatttta ttggtctttt cagttggttc tcctatacgc
    16141 ttccaagaat cagcaacaaa gaaatatcct ggattataat aataagttgc acgataattc
    16201 gagtaaaaat actcatcagc ttctcccaga taagaagaaa tttctgccac aattcccatt
    16261 tcttctatca gctcacggac aatcgcttct tctttcgtct cttctccttc aatttccccg
    16321 ccaggaagaa aaaaagcacc atttggagcc tcgattactg caatctgctg atctctttct
    16381 atgacaatat atgctgcata acgggtttga taatcagcaa attgcttttt ttcaccaaaa
    16441 attggtttat ccatgaatag tttccacctt aacagtttta ttttctatcc attttacatg
    16501 agaaatttct catgaacaag cacaaatcaa ctatttcctt acttcttttt gttatgattg
    16561 agtaaaagga aaaggagaga tgaatctatg aaaatggctc acacatgtgt tcgagtgaaa
    16621 gatcttgaag catcaatcga attttatcaa aaggcatttg gttttgaaga aagccgccgc
    16681 cgtgattttc cagaaaacaa atttacactt gtttatttga cacttcctgg ggatgactat
    16741 gaattagagt tgacttacaa ctatgatcat ggtgcgtatg atctaggaga cggctatggt
    16801 catatcgcta tagcagctga tgatctagaa aaattacacg agcaacataa agctgctggt
    16861 cttgagatta ctgacttaaa aggattacct ggcactgcgc cttcttacta ctttgtcatt
    16921 gaccctgatg gttataaaat cgaagtcatc cgaggatagt tagtatgggg cattttactc
    16981 ttgattgaat aaaaaacaaa caccaataat taaaatgaga cgcaaacttt tcattaaatt
    17041 gaaaaagttt gcgtcttttt ttaacaacca ttgtagctat aaggttgcca ctctccacca
    17101 atttattttt aattcatttg aaagaaatca aataaacgag gtacctttag aaaacaaaac
    17161 tgcttttcct cctattatca cacgatcttc ttttaattca cattctagat ccccgcccct
    17221 tgatgacatt tgataagctg acaattttgt tttattcatt ctttctgccc aataaggaat
    17281 aagattagaa tgtgctgatc cacatactgg atcttcattg attgttaatt ttggaaagaa
    17341 ggttctagaa acaaagtctt tttgcacact ttctgctgtc acgatgactc ctattcctaa
    17401 ttcaaaattt ttgatagctg taaaatctgg ctgcaattta gccaccgttt tttcatcttc
    17461 taatacgaaa aataaatcac gtgctaagta ggcttcttta atcttagccc caatcgcttc
    17521 ttcatattca gacaatatcg gcactttttt cggcataata ctaggaaaat ccatgtaata
    17581 ataatcttta attcttgtca caaatagatt accgctttga gtagaaaatt taatcgtttc
    17641 atcaggtatt ttgtaatagt taaataaaac aaatgctgtt gctaatgtcg cgtgaccaca
    17701 aagatcgatt tctcgatctg gcgtaaacca tctaagctca aattcttggt ttttcttcac
    17761 tgtaaatgct gtttcagata aattgttttc aatggcaatt ttttgcatcg taccttctgg
    17821 cagccattct tctagcacat aaaccgctgc tggatttcct ttgaacacct catctgcaaa
    17881 tgcatcaact acgtaataat ctaagttcat tttaaagccc ctttctctaa tttgttataa
    17941 atatattctg cacaacaaag atcttcaata gctagaccaa ctgcgtcgaa aatcgtcggc
    18001 ctcgattctc ctttataaaa tgtttttttc tcagaaacta attcgcctaa tgtaccaaca
    18061 atacaagatt cctctaaatc tccttctgcc atggctataa gcaggtcccc gctttctgtt
    18121 aaggcagctg agtaatcatc tacatagatt tgagaagttt ccatcaacga tgtacttatc
    18181 tctcttgtat caggagtaaa tgtgcccaca gcattgatat gtgcgtcttc ccttacccac
    18241 tctttttgaa gaaatgcctc tttactagag gtcaacgtac aaatgatttc cgctggacgt
    18301 actgcatctt ctactgatat tgcatttata aacgttattt taggatactg ttttttagct
    18361 ttagcgataa aagtatttcg tctttcttct aaaatatcgt aaacaaacac tgtagtgatg
    18421 ggacgaatgg tagaaatcgc agtcaaatgc gacaatgctt gttgaccagc tccaattaaa
    18481 gcaagtgttt ctgcatgcgg atttgctaag taatctgttg ccagcgcaga tacagcagct
    18541 gttcgaatcc aggtgactgc atttgcgttt atcaatgctt tgggtagtcc gttttgagca
    18601 tcaaacaaga aaatctctcc taaatgagaa ggtaaatgat actgatgatt atccggaaaa
    18661 gcggtaatga cttttgtgcc aaaatatctg ttctccccca aataagcagg catcatcgca
    18721 aacatatttt tgccttttcc gtcaggtaaa atttccacca atcgaggatt ttggctgatt
    18781 ttaccacttt cataatcaaa aaaacatttt ttcattactt gaatcgcttc ttcaaaacta
    18841 aaagaagcta ctacttcctc aaaattaata attttcatag acaattccct cctcacaaaa
    18901 gattaacttc taaaatcaat acaatcaatg gtaaaattgt atggtataca attttaagga
    18961 gtggagaaaa tgcctattaa ttcttatgac aattacccgt taacttggcg accagacaaa
    19021 caaaaattga agcgtcctta ttatcgatcg ttgattcaac aattagaaca agatatttta
    19081 aagaataaat tacagaaaaa cactcagtta ccctcccaaa gagagctagc tgattattta
    19141 gatttaaatt ttactaccgt tggcaaggct tataaatatg gaattgagaa aggtttgctg
    19201 tatacgaata ttggaagtgg cacatttatt tctcccaatg tctttgagtc catcaccatc
    19261 tctaccaatg aagtaaccga acatatcatt gattttggtc tggttagttc ttttgaagaa
    19321 tgtaataaat tcgttgtccc gtttattcaa tcaactagta ataacccaaa tcttgttggt
    19381 ttgcttaatt accaagatcc caaaggcaca aattttcaat tgactactgc agcaaattgg
    19441 ttaaaaactc aaggagtcat tccgtcctta gaatctctat ctattgtttc cggtgttcaa
    19501 aatggattgg ctatcacact ttctgcactt ttctctccag gtgatagaat agcaacagac
    19561 cgatatacat acgctaattt cattgaattg gctcagttat atcatttaga gatcgttcca
    19621 attgattttg acgagcaagg aatgcgacct gatatattga ttcaggaatg tagaaaaaag
    19681 aagattcatg gtgtctttct tatgccttct tgtaataatc ctatagggtt tcaaatctct
    19741 cacaaaagac gagagcaatt agccgaagtg attgaaaaag aaggtctatg ggttattgaa
    19801 gatgatatcc attcattttt aacaacttac tatcaacata cgatcattcc tcctttccaa
    19861 aatttattac ctaaccaaac aatctactta gctggaatga caaaatttat ttgttctgga
    19921 ttgcgagttg cttatcttgt agttccagta catgtccaaa gcaagataga acaagcaatt
    19981 tttaatataa atgtgaaaac ttctggatta gatgtggaag tcatcactca aatcctccat
    20041 tcaaatgaag caaataggat cttagaaact aaattaagtc ttacaaaaag agccaatcag
    20101 ctttttgatt ctcttttcaa agtagaaaaa ccaacgaatc gtgtccctta ctatcgaatt
    20161 cttccagttg atcctgagat tgaccctaag ataattgaga atgactttct tgctaacggt
    20221 atccgacttt atcattccag acgctttact acacgtacgc aaccagatgc attcgttcga
    20281 atttccctat cctctaataa ccttgaaatt ttagcttctg gactaagtat cgtaaaagaa
    20341 aaaataaaaa aatatgaatt ataacctatt gataaataaa ggaatcaaat cttattgatt
    20401 cctttcaata aaaaagaggc actacccgag gttcaacaac gggtagtgcc tcaaaaaata
    20461 aacgaacatt ttgcacttaa agtatccaag aagcaagaaa a
//
LOCUS       DADVXK010000043        20213 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.043, whole genome shotgun sequence.
ACCESSION   DADVXK010000043 DADVXK010000000
VERSION     DADVXK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.043"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            20..781
                     /locus_tag="KB909_001497"
     CDS             20..781
                     /locus_tag="KB909_001497"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6837523.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENYDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            1001..2320
                     /locus_tag="KB909_001498"
     CDS             1001..2320
                     /locus_tag="KB909_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6837524.1"
                     /translation="MVAYDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFG
                     KPKRSSINYAPAFSKMEPRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTR
                     KQPLIVYITTAGYVLDGPLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPR
                     LWIKANPNICLMNFVGMLDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKR
                     NNKTIDIETLKGKKCVGGFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDN
                     NQERIKAWEKVGDLTIIPGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELE
                     NAGFETNEIRQGFLSLGGPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWM
                     PSKQSKSRKIDGFAASLNSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            2336..3556
                     /locus_tag="KB909_001499"
     CDS             2336..3556
                     /locus_tag="KB909_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6837525.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            3591..4268
                     /locus_tag="KB909_001500"
     CDS             3591..4268
                     /locus_tag="KB909_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBB6837526.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            4265..5461
                     /locus_tag="KB909_001501"
     CDS             4265..5461
                     /locus_tag="KB909_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6837527.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            5476..5799
                     /locus_tag="KB909_001502"
     CDS             5476..5799
                     /locus_tag="KB909_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6837528.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            5803..6138
                     /locus_tag="KB909_001503"
     CDS             5803..6138
                     /locus_tag="KB909_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6837529.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            6135..6530
                     /locus_tag="KB909_001504"
     CDS             6135..6530
                     /locus_tag="KB909_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837530.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            6527..6898
                     /locus_tag="KB909_001505"
     CDS             6527..6898
                     /locus_tag="KB909_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837531.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            6914..7474
                     /locus_tag="KB909_001506"
     CDS             6914..7474
                     /locus_tag="KB909_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6837532.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            7601..7912
                     /locus_tag="KB909_001507"
     CDS             7601..7912
                     /locus_tag="KB909_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837533.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            7936..8127
                     /locus_tag="KB909_001508"
     CDS             7936..8127
                     /locus_tag="KB909_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837534.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            8127..11972
                     /locus_tag="KB909_001509"
     CDS             8127..11972
                     /locus_tag="KB909_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBB6837535.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            11973..12845
                     /locus_tag="KB909_001510"
     CDS             11973..12845
                     /locus_tag="KB909_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBB6837536.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            12842..13891
                     /locus_tag="KB909_001511"
     CDS             12842..13891
                     /locus_tag="KB909_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837537.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            13895..14719
                     /locus_tag="KB909_001512"
     CDS             13895..14719
                     /locus_tag="KB909_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837538.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            14737..16869
                     /locus_tag="KB909_001513"
     CDS             14737..16869
                     /locus_tag="KB909_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2479 domain-containing protein"
                     /protein_id="HBB6837539.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDKTNDRIDQTNQQIGDLGKLKKMYSNSIDFGDYD
                     YSGNPNLSAKLNASSFSLGTGATVADDNDEIVFTLDGTNQLSKYASKAQVPVAEGKQY
                     TISCEIMLEDGFTGDPSGIRLQHAYLPGGVVVLQTETVPKNELNTWQTLIGTRTVKYT
                     SDVPNEWYPLFRDIRTLKPTGKVRLRKIKIEEGSTATPYQPNLLDDPYWLGKAPLGEN
                     IANKSVTFPIKSSAYSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRY
                     GNLEPVEGLVDTWGLTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGNTRTP
                     NISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEI
                     NSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSA
                     KLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQL
                     SIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            16886..17035
                     /locus_tag="KB909_001514"
     CDS             16886..17035
                     /locus_tag="KB909_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837540.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            17032..17478
                     /locus_tag="KB909_001515"
     CDS             17032..17478
                     /locus_tag="KB909_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837541.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            17480..17617
                     /locus_tag="KB909_001516"
     CDS             17480..17617
                     /locus_tag="KB909_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6837542.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            17654..17947
                     /locus_tag="KB909_001517"
     CDS             17654..17947
                     /locus_tag="KB909_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837543.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            17970..18167
                     /locus_tag="KB909_001518"
     CDS             17970..18167
                     /locus_tag="KB909_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6837544.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            18178..19197
                     /locus_tag="KB909_001519"
     CDS             18178..19197
                     /locus_tag="KB909_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6837545.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            19454..20101
                     /locus_tag="KB909_001520"
     CDS             19454..20101
                     /locus_tag="KB909_001520"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6837546.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
BASE COUNT         7122 a         3374 c         4471 g         5246 t
ORIGIN      
        1 tataaaagag gtgagtagat tgaaaaaata cattatttac aaacacttaa ataaaataaa
       61 tggcaaaatt tatatcggtg tcacaaatga tattggcaga aggtggagga gcggtgggat
      121 tgaatataaa ccaccaaaga acgaaaccca acaccacaga agtttttgga atgcaataca
      181 aaaatacggg tgggaaaatt atgatcattt gattattgaa gaagacttaa cgatgaaaga
      241 agcttttgag aaagaaaagt tttatattga actttatgac tcaactaata agaaaaaagg
      301 ttataacatc gcaaaaggcg gaaatggcgg aataatatat aaagttcacc ccaaaggaat
      361 gctagggaaa aaacaatcta aagaattttc ttcaaatcac agtaaatggg caaagaacca
      421 taagaataat tgtatgacaa acggtgatgt tgtatggggt gttactcacg aacacccaaa
      481 aggcatgttg ggaaagcacc acagcaaaga atcaattatg aaaaagaaag catatagtgg
      541 tgaaaatgct gtaacctcaa aaccaattgt cgcaattgaa cgggatggaa ctaaaagaga
      601 atttcacagc gctaagcttt gcatggctta ctattcgatt agtacatgtg ttttttaccg
      661 acttttaaaa gatggcgccc cttatgtgat aaatcctaaa gcgaactaca gaaataaaga
      721 aaaaatatta gctatcgaag gaattatgtt caaacataaa gaagataccg aggtaagtta
      781 gtagattgcg aaaggttact aactaccgta acgcgtagga gttgaataaa tataatgctc
      841 ccaagagtgt ccgacagcag ataatttgct gaaaatgtac gctaaactgg gccagaactg
      901 actgaccgat gaaaatgagg gtgacctcca gagtgcgaga taaaaagctc gcagataata
      961 acaatcgaaa acatcactaa tttcaggcct ttccacatac atggtcgctt atgatgatga
     1021 acaaggcgcc aacgtttacg tattggcaaa tgctcgtgat caagcaagct tgttgtttga
     1081 taaggccgca gaaatggtca aacaatcgcc ggcgctcttt aagaaatttg gtaagcctaa
     1141 acgatcaagt attaattatg ctcccgcctt ttctaaaatg gaaccacgcg cctcagatag
     1201 ccggaaattg gatgggctaa acactcactt tggtattttt gacgagatcc acgagtttac
     1261 gaattacaat ctgatcaacg ttatcaagaa atcaagagga accagaaaac agcctctgat
     1321 agtttatatc acaactgctg gatatgtatt agatggtccg ttgatgtctt attttgagca
     1381 aggtgtggac tgtttggaac atttggaaga tgacatcgat gaacggactt tctattatct
     1441 ggcaaaactt gacagtgcgg aagaggctga tgacccaaga ttatggatca aagccaatcc
     1501 gaatatttgt ctaatgaatt ttgttggcat gctagatgac tatgttaagg ataaaaaaga
     1561 tccaaaagaa tatgctgact ggattaccaa gcaatttaac ttgttttccg atatcgatga
     1621 gctgtcattt gtcgatatgc ctaccattaa acgaaacaat aaaaccatcg atattgaaac
     1681 gctcaaaggt aagaagtgtg tcggtggttt tgacttgtcc gaaacggaag actttaccgc
     1741 agccgtttta gaatttccgc ttgaaacagg cgaggtattc attttgcaac acacatggat
     1801 cccacaagct agatttgatc gagataacaa tcaagagcgt atcaaagcgt gggagaaggt
     1861 gggagatcta acgattattc ctggtgatta cgtcaattat gaatacgtct taaattggtt
     1921 tgtagaaaat tcgaaaatct atgacattgt aaaaatcaat tatgacaagg ccaaggcgct
     1981 acgattaaat aaagaactag aaaatgcagg atttgaaacc aacgagattc ggcaagggtt
     2041 tctatcatta ggtgggccaa tgcaaaactt caaggaaatg ctattggacg gtaaggtgat
     2101 tttcaacaat tccaagcttt accgatggta tctatccaac gtcaagctgg tgatggatcg
     2161 caactcaaac tggatgccgt ctaagcagtc caagagtaga aaaatagatg gttttgcagc
     2221 aagtttgaac agccacgccg aagtgttgaa tatgttggtt aatcctgtcg gaaccgggaa
     2281 agtaacctat tactcgattt ccgatttaat gaatatgtaa gaaaggtgtg gaggaatgag
     2341 tattttagat cgtttgcgtt cttttggccg agcgaagccg aaagcgagca aacaagagta
     2401 ttttttgaat gacccgggat tgataccgta tttagtcgga aaagatgaaa tatcagaagg
     2461 gattttttcc gtaattagcc gtgtatcgaa cgtttttgcg tctctccctc tcaaaatgat
     2521 agatgcggag tttggccaac cggacgactg tcctgcatac aacttgttga gcgaaggccc
     2581 tcgatatttt acaaagtttg attttttccg ggacgtggaa gttttgagaa actaccaagg
     2641 gaatgcgtat gtgcagattt tccgaaatat caatggagaa gtagcagata tggcgttaat
     2701 aaaacctggt gcttgccatc cagtgattga tatggatagc ggggagcttt actaccaagt
     2761 aactgcgact gacaaaggca gttataagca agttatttat gtacattaca tggaaatgct
     2821 ccactttaaa caaccgaggt ttggtggctt ggaaggtaca gaccccacaa aagtattaac
     2881 gaataccctc ggatatgatc gagaagtccg aaaaatctct ttaagtcagc ttaaaggagg
     2941 taatgaaggg ctaaaagtta agtttgctag caatgtggat gaagaagcta aaaaagctac
     3001 agttaaaaac attgctgatt tttatcgaca aaacggtgga ctacttgtgg aagaaaacgg
     3061 tgtagaaatc gaacgtttac aacgagagct ggtagacagc aagcttttag atactgataa
     3121 agtatctcgc tccagaatcg cgatggtcta caacgtgccg gaacatttca ttgggagtaa
     3181 ccagtcgagt tactcttcac aggaacagct caatatggag tttttgacat acaatctagt
     3241 accgaccgtt aatcaatatg aagcggaact aaataagaaa acactatcga gaaccgaaaa
     3301 agcaaaaggt tatcgatata agtttaatgt cgcaagtttg ctaagagctg acactcaggc
     3361 aagggggcaa ttctatcaaa tcatgcgacg aggcggagca tactcagcga atgatgtccg
     3421 aagatttgag gacttgcaac cgataaataa aaccggtatg gatgattatc atatttccgg
     3481 agacctatat ccaatcgata tggatccaac attaagaaaa acaaactcgt ctaaaagcgt
     3541 agccgaaaac ggttaggctt ttttagtttg caccgaaggg aggtgaaagg atgaaaaaag
     3601 tgacgttaag cggcgatgtc gtggataacg ataccgcgtg gttatatgac tggtttggga
     3661 ttgattgtat ctcaccaggg aaaatttctg ccgctcttac agaagcagcg ggggatgaag
     3721 tagaacttga tatctcatct aacggtgggg atgtcctagc ggcaagcgaa atatataccg
     3781 ctatccgtgc ctatccggga aaggtatccg gaaatgttgt gagtattgca gcaagcgctg
     3841 caagtgtaat cgcttgtgct tgcgaaccgc ttagaatctc gccaacagca cacatcatga
     3901 ttcacaacgc atgggtgacc actagcggca acgccgagga attaaaagcc aatgcggaaa
     3961 tgttaagcag tgtggatgag tctatcgtta atgcttacga gatcaagaca ggactcgacc
     4021 ggaaaaagct tgctgattta atggcaaaag atacttggtt aaacgcacaa acagcagtgg
     4081 cggaaggttt tgcggatgaa attatgtttg cagaagcacc agtaacggta ctcaatgcct
     4141 ctcaaccggt tattccaaaa aacgcggtaa ctaagttgaa aaatctaata ctcaaagcgg
     4201 aaacaccgca agaagaaacg ctcttgcaga aaaaactaaa agccttaaat ggagggaaaa
     4261 acgaatgaat ttagaacaat taaaaaatgc gtgggtcgag gcgggaagta aagtctctga
     4321 tttaaacgcg caactcaatg cagcattggt tgacgatgaa aaaacagaag aagatgtagt
     4381 aagtttgcaa gcacaagtaa aagcagcacg ggctaaacgg gacggattga aagagcaagt
     4441 ggcaaatatg gaagccgaac aagtcttaaa cgtcaaaaaa gaaccattag ataaaaaaga
     4501 tgaaaacttg aaaaacaagt ttatcaaaga ctttaaagcg atggtcaatg gtgatcctgc
     4561 tattatggct actttgacat ctaatacgga tgaatctggt aatgctatcg gattgactat
     4621 tcctgtagat gtgcaaacga ctattcatac tttggttcgt cagtttgact ctttgcaaga
     4681 atacgtaaac gttgaaaaag tgaccactac tagcggttct cgggtttatg aaaaatggtc
     4741 tgatattaac ccactgaccg ctttggatac tgaagacggt gaaatcccag caaatgatga
     4801 tcctgcactt tacttgatca aatacttgat caaacgctac gcaggtattt ctacagtaac
     4861 taacagcttg ctaaaagata ctgccgaaaa cattttggca tggttgtcta actggatcgc
     4921 gaaaaaagta gttgttactc gcaatacaaa aatcttggca gctattgatg gaatcaaagc
     4981 agcgcaaaag aaagatgtta cagatgttga tgggattaaa gatatcataa acgtccaact
     5041 tgatccagct atcgaagcta catctatgtt tattacaaac caagatggct tcaatgtttt
     5101 agataaagtg aaacgtgctg atggatctta cttgttacaa aaagacgtag cttctgcaac
     5161 tggatatacc ttcttaggta aaccaatcaa gaaaattgct tctcgtttct tgccaaacaa
     5221 aggtacgcaa gctactccta aatatccact gtatattggt gatctgaaag aagctgttac
     5281 attgtatgat cgcgaaaaca tgagcttgct gacaacgaat attggcgggg gggcttttga
     5341 aacagacacc accaaagtac gggttatcga tcgatttgat gtgcagttag tcgatgatga
     5401 agcagttgtt ttagctacat ttacatctat cgcaaacgaa gtgccagtaa caaacggtta
     5461 aggagctgat ttcttatgat tcttgatcct aaaatggatt tagacgaaat caaaaacgca
     5521 ctaaagattg ataccgatga tgacgatgtg gaagtaagac gtgcggtgca agctgcaatt
     5581 gcatacatta gaggggctat cgggaatgat aagccctctt tttataagca agaaaatgac
     5641 acggttgatc tgattaattt agctattctg caattagcag atcattatta caacgctcga
     5701 tcagcaaccg tgagtgggaa cttgcgagag tacgatttag gttttacaag cctaatcttg
     5761 caactcaaag caagatattt gctttttgtg gaggagtagc gtatgcccct tattcaaaca
     5821 ggaaatttaa atcaacgcat caagtttgtc cgagatacga cggtcaagga cgaggacggg
     5881 caagttgtcc ggacttctac aaccattctt acttgctggg caagtgtgca gacacaacgc
     5941 ctgaacgata ttaagacgtc cattggtacg gctttggaag gaacactgac gttcattatc
     6001 cgctatcaac aaaaatcaga gctaaccaat gatatgaaag tgcgttggaa tggaaaaacg
     6061 tttgaaatca ttacgattac gaaaggcgag tttgcgaagg acttcacgac aatcattgca
     6121 aaagaggttt caaaatgagt gtagaagtcg atgcaaccga agtgtacaaa gcgcttaggg
     6181 aagtaaaagc aaacgttcaa cgagtggaaa gcccagcact tagaaaagct ggggagtacg
     6241 ctcaagaaaa gttacaacaa aacacacctt actgggatgg aacgaagtca aacggtaaac
     6301 gtggttcgta tatgcaagaa catgctaagg accatgtggt tacaagctcg gtaaaaaacg
     6361 gattgataga agtcggctat gataaagatg tttcttggcg gatgcacttt atcgagttcg
     6421 gaacaatcaa acaacgtcca aaaggtttcg tacaaaaaac acaaaagcaa atcgaaaaac
     6481 aagtaacaca aatcattgct gacgaagtaa aaaggaggct aggactttga aaacggcagt
     6541 atcacaagtc tattcaattc tgaatagcaa tgaaaaaaca aagaacattg atttttacac
     6601 caatagtgtt ccggaatcgg ctcaaacagt acctagcctt ccagttggca gaattacaga
     6661 gatattcggc aactatgaag atttcgcaag caacaatcct ttgaccattc aatttaacgt
     6721 acaggtagat gtatgggtat cgaccttaaa agaggttgat gccttttatt ttgcccttga
     6781 tgagattatg agggggaatg gttggcaatg cgcatacacg gaacaaacag atgatgagga
     6841 tttagaaggt gcaaagcgga ttatcaaacg atatgtagca aatatttcac taaattaaaa
     6901 ggagagaaaa tagatggcaa cagtaggatt tgagagcgtc atttttggcg taaaaacagg
     6961 tgcaggcggc actctaaaag aattagtagc agataagtcg aaaggcggag cgatcgaagc
     7021 taaaattact ggattaggcg caacttctaa cacaacatac gcttcaaacg taccattctt
     7081 cattgcaagt aaaggggttt cgtcgccaaa agttacgctt gacgtggcag acttaatgga
     7141 taacggcatt tacagcgaaa tcattggcgc taaaaccgtg gatggtgtaa atgtaattgg
     7201 ttcagaaact gaagcgcctt acgtgtcggt agtcatggtt acagcgaaca aagaaggaaa
     7261 acgcttattc atgggattgg caaaaggaaa attcagtcat ccagatatcg acatgaaaac
     7321 agctgaagac aaaggagttg aattgcaaac cgattctatc gaaggggaat tcatttctga
     7381 tgaacgtggc tatgtatact taacagccgt agaatcagaa gaaatgacct tacaaaaatt
     7441 caaggacttg gtaaataaca aagcggggga gtagttaacc ctgcatctac accaacgaca
     7501 gatacaggga caccaaaaga accagaacca aaaattgata cacaaggtta gccatttttt
     7561 ggctagcctt atttttttgt aaaaacaagg aggaaaacaa atgattgaat tgcaattgaa
     7621 acttgacgga aagaaaaaaa cattcaaaca acaagatatt tccgcacgtg caatgcgtga
     7681 gtgtatcaaa ttttacgaga aagcggaaaa agcagaccta actgatttag aagcaattga
     7741 ttcaatgatt gcaattacag cagatatttt ccaagatcca gcagttacat ttgatgctat
     7801 tttagacggt ttgactgcga gcgagttagt accggcatta gaaagtgttt ttgaacaaat
     7861 caatgaactg ggaaacaatg aaaaaaagca gacggcgagc aaaaagagat aagtttttct
     7921 gaagctagga aagcaatgga tcaaatctac aaagatttaa tcgaatcagg ttggacgatg
     7981 agagatgtgg acgaagccga ctatcattat ttgttacacc tttttggaga agtggagagt
     8041 ggcgaagaat atgtagatgg tgctgatttc atcaaacaat ttttatcggc tgaagacttg
     8101 gtaaaacttg aggaaggagg taaataatgg caggaaaagg acaaccggca ggaaatatca
     8161 agctagggat tagtttagat agcactaatt ttggtaacac gctggacgaa atcaatgcga
     8221 aagtcaaaca agctgagtcg aatatgcgtg ccaatctaaa ggcttatgat tcagcaggac
     8281 gttcatacga agcacttagt caaaagacga aagacttgtc tacggttatg gaagggcaaa
     8341 acgccaaagt aagagaatta acaaagcgcc gtgatgaagc gattagcaag tatggcgagg
     8401 aatcgaaaca agttgctaac cttaacacac agataaacaa tgctaccgca aaatataatg
     8461 cttacagtcg ccagttgaat gacacaaaaa aagaattggt gtattccaaa acagccgtca
     8521 atgatttatc taacgaaatc aaagaaaatg aacgacaaat gaacgccgaa gtaaaagcgt
     8581 tgaaagccgc tggtgatgaa tctggtgcgt ttgaagcaaa acaaaaaggg ctagccaaac
     8641 aaacggaatt atccgagaaa gctatcgaag aacagcgcaa agttgtgaaa ctgatggctg
     8701 atgagtttgg cgattcagca aatgaaaccg aagatgcaaa aagggcatta gaaaagttag
     8761 aacgacaaag ccaaatatct agcaggcaat tagaagcact caaaagctcc agcgatcaat
     8821 caggaaaaaa aatagaagat tttggcgaca agtccacaag gtcagctagg aaactggatg
     8881 ggctaaaaga caaattaggc tcgctaaaaa gcgcattttc gtttggtgca gttgctggat
     8941 tagcgcataa cgctattagc agtgtagtaa gtggcgtgca aggcttggtt ggcgaagcag
     9001 taaacgcatc ggattcattg atgaagtttt ccaaaaccat ggagtttgct aactttggga
     9061 agtcacagat agaaagctcg aaaaaagaaa tgaaagacta cgccgataag acggtttatg
     9121 gtttagaaga aattctgaac acaaccgcac aattggcatc taacgggatt cctaactata
     9181 cagaactaac caaggcggca ggtaacttga atgccgttgc aggcggttct agtgatacat
     9241 tcaaatccgt tgccatgatg ctaacgcaga cggcaggagc tgggaaacta acaactgaaa
     9301 actggaatca attagcagat gcgataccgg gcgcttcagg gctgttacaa gacgctatgt
     9361 tgaaaaacgg agcttataca ggaaacttcc gtgatgcaat ggcgcaaggt caaatcactt
     9421 ctgatgagtt taaccaagcg attgtacagt taggtatgaa tgacggagca gttaaagcag
     9481 ctacttccac agatacattg agtggttctt gggaacagat gaaatctact gtaataaatg
     9541 ggttacaaag tatcatagac aaagtaggcg ttgaaaatat cactggtttc atcaacagag
     9601 taacaaaagg gattgaaaat tctattccta aaattactca atttataggt tggttgagag
     9661 atattggaac gtggatcgtt gaaaatagag agccactaac atggattgtc ggaatcatag
     9721 gcggaattac attagcagta aaagcattga acgtagcaag tatgttgctg gcaattactg
     9781 gcggaacatt ggcagcccct tttgtggcga ttggtgtagc attaggcgca ctagcaggtg
     9841 ctttggtgat agcttataca aaatctgaaa catttagaaa tatagtcaat gcggctttta
     9901 cagctgtgaa aaacgtagtt atgagcgtta tcaataattt ggtggaatac tacaaaatgt
     9961 tgtggagcgt gttgcagtgg ctttgggaaa aaataaaaga atgggcttca tggattggca
    10021 ataaattcat tgaaatgaag aacagcgttg tgaatacggt tcagaaccta tggaatggtg
    10081 tgaaaaactt cttcagtaat ggcgttggag acacttggaa taaggtagtt ggctgggtaa
    10141 aaaacatttt caacaaagca actgaattga agaacaaagt ttctgatgca attggtaacc
    10201 tgtggaacgg tatcaaagac acattccgta gaggcattga tacggtattc aattggtttt
    10261 cagaactacc gacgaagatg aagaatgcca ttattggcgg taaaaatgcc attgttgatg
    10321 cgttcaaaag tattttcaac gcagcactta aagcgatagg taaaccagtt aacgcaatca
    10381 tccatggagc ttcatgggta ctagaaaaac tgggtgctga caaactcgaa gaatggaaag
    10441 tgccacaata cgcaaaagga acaccaaacg gaggtcatcc gggcgggcct atgatggtaa
    10501 atgacggtag aggtgctgaa gcggtaatca cacctaacgg acaagcattt atcccacgag
    10561 ggcgaaatgt agtgttgaat gcaccaaaag gcacacacgt tctaacagct gaagaaacag
    10621 cttatatgac tggaaacaaa gcaccaagat atagatacgc caaaggtaca ggctttttcg
    10681 gaaatctatg gaacaacgtc aaaggatttg ctggagatgt tggaaacaag ctgaaagatg
    10741 tagtcggcga tgtatgggat tttgtaacag acccgggagc gttggctagg aaagtgttaa
    10801 atggtcttgg cgtactggaa gggcttgtca aatatccttt agatgttggt aaaggtattc
    10861 taagcaaggc taccgaagca ttgacgaaca aaatcacaga actattcagc agtggcagtt
    10921 tagacacttc aatgggcatg caaggcgttt acaaatactt ggcggacgtt gcagttgcag
    10981 taatgaagaa gtttccaggc tttgtggcaa ctagtgggta tagaccaggt gacccctatt
    11041 cgcatggtaa acgtaatgcc attgatattg cactacctgg tgtcacagga ggctcgccac
    11101 gctacacaga agcagccaat tacgcatttg agaagtttgc aaacaaaatc ggctatgtta
    11161 tcacaaatgg caaggttcgt gaccgttcag gacaatcagg tacaggtatt cacaatgatt
    11221 ggagaccatg gcccgatgga gatcactatg atcatgtgca tttaaacggt gtgaaagacc
    11281 cacaaaacac tcaaatttca ggagatagcg tgggaggcag tggggtagaa agatggcgca
    11341 atgtagcaat tagagcgttg aaaatgaccg gtcaatacag tactgcaaac ttaaatgcat
    11401 tactaaatca aatgcgtaca gagtcaaatg gtaatcctaa tgcagttaac aattgggata
    11461 ttaacgccaa aaatggaaca ccatcaaaag ggttgctcca agtgattgac ccaacattca
    11521 gacagtatgc aatgccagga ttcaacagca atatttttga cccactatct aacatcttag
    11581 cttcaatcag atacgcacta tcaagatatg gctcactaac aaatgcctat cgtggagttg
    11641 gttacgcaaa cggtggaatt gtaaaccaac atcaaattgc ggaaatcgca gaaggaaaca
    11701 agccagaaat tattattcct ttagataagg ctaaacgatc aagagcgatg caattattgt
    11761 ctatcgcaat ggacaaacta ggagtttctc ctaaaactta tggaaatgcg acaactgttt
    11821 ccagtgatta cgaaatccta gaagccattg aaaaacaggc ggcaacaacg aatcagctgt
    11881 tatcgttatt gctggcattt ttcaaaggaa atagccgaac tgatagagat ttagctttag
    11941 atattcagaa gatcttggtt aggaggatgt agatgcgaac tgtattactg agaaatagaa
    12001 taaacgaaga aattgatttg tctacggagg attattttgc tactgggttg agtaatatgg
    12061 ggtttgaagt aaaaaaagaa catgtgggac agtgggggaa tttcagagaa agcagtgaga
    12121 acgttgaaat atctgaattt cagtcatctg taatcatttc tgtgcatggg tttcgagaaa
    12181 aagaactgta caattcactt gtgcagttcc tatcggaagg tccgtttgaa ctggaatttg
    12241 cttttgacgg cgaaacaatg gtaagaagat gcagtctaaa atctttaagt aagactgaaa
    12301 tcgatccgaa aacatcgtta ctaacagaca ctttagaact atatttcaca tcaaactggt
    12361 attccgtaaa acgcgaaaaa ttaattcagc gaccgaatgt agtgaaaaca cgtggtaagg
    12421 tttttccgta taaaagatct tatatctaca ctcaaaactt gtgggagaaa aaaggtgtat
    12481 tcaaattcaa taataattct gtatacctaa cgaatagcaa ggaacggatg tccccgctaa
    12541 aaattcgtgt gattgggaag tgttcaaatc cgtattggga agtaatccaa aactcacaaa
    12601 tcatcgcaac ggatggatac ttcatagata tgactgaaac acagactcta gaagtatcaa
    12661 gcctttttga agatacaacg gcgattttaa aagatattgc aggggtagaa tcttctgtct
    12721 accaacaaca ggattataca aaaactaatt ttgttcaggc cccgactgga gaattcagca
    12781 ttgtgtttca tgttgggggg gcagacgtag agattgagtt atacgaggag cgtgatctgt
    12841 tttgatttta gcagtcacgc tttttcatcg tgatttaatg ctttataacg aacatttatt
    12901 ctctaacagt tttgaatttg gtgcggacga gatcaacgaa gaggctagta gctttacgat
    12961 ggataagtac gttcctgtaa aaacaggcga ttttctacta gcaaaatata ttcctagtgg
    13021 aaaatttgca tattttggtg taattacgtc gcaggaagac gaaaaaatca gttgtaaaag
    13081 cttacttagt ttagctgata gtgagatacc gactgcacgt gtgtcaggag ataactacga
    13141 agagcatatc cggcggttga ttgaatacta tttgctgaat gatccaacga aacaactaaa
    13201 agatatttta gacgtcaaag cagaaagtgc gacctctcat tcgtatcaag ctaccgatac
    13261 gaataaacac aagttaagtg cgtatattct caatggtttc aaaaaataca acgtaaaatg
    13321 gtatttcaag ggaattcaaa acagaaaaat ctatacaggc atacgtgctg taaatgaatc
    13381 aatttacatt aaagacaatt cttctgaatt tagcgattgg gatgtgtttg ttcaggcgcc
    13441 gggcgctgga aacgagaaca agctattaat cgttgataaa gcaatgaaag atatagagaa
    13501 accgataata ctgtcaacat ggtatttgga cgaagaaaac aatttgacac aagatggatc
    13561 gaaagaaaat atcacgaaac caactgtcaa tttggttaat atctacgatc aaaccgcaga
    13621 agataaagca tcctacgaag atgtggcaaa atcagagttg aaaggcaata cgtattcgca
    13681 tgaaatcaaa gtgaacgttg taagaaatgc aaaaaatttg aatgtcgaaa cgattgaaac
    13741 agggatgttt gccacgattt cttataaagg aaagatatac aagtcggttt tgacagcttg
    13801 gcgaatatca agtgataagg agtttgtgga attgactttc ggaaacataa gaagtcgttt
    13861 tatggattat tttgaagata atgggggata aaaaatggtt agcaatgtgg atggatatca
    13921 atttgaaaac gtgaaagtaa gcgcagaaaa tgatgctaga ctttatcacg ttttatataa
    13981 tcggaaaaat caggttattg atggttacga tcagtctatg aatttatctt caagcggatt
    14041 aacagtaaaa gttgctgcag gagcagcgat tattcaaggt cgtatggtcg ttgttcgaca
    14101 agaagaaagt ataacagttc cagcaaactc aagtggttat atagcattaa cagtggattt
    14161 gacacaagaa gttatacctg gatctattct tccagaatcg gaagaatatg aatggactaa
    14221 taatcaagtc aagctagaat ttataacaaa agttataaaa ggtaatttaa acaatggtga
    14281 taaggtctat aatttaccac tatgctcagt tacttctact ggatcaactg tttcaatctc
    14341 aaagatatcg gatagttacg agctgactct ctctaaagga gaaattttgt ggagtgggac
    14401 tgcgttaatg catgatactc aaactgtcca accttcaaaa aaaatgtggc agacagtttc
    14461 aggtttttta ttagtatggc tcccatacga aaacgggcaa gcaattgggg atagatatgt
    14521 aactacgcct ttttataaag agcgtgtaac ttttactaat gttttaggag aaattgtttc
    14581 aggatttgat gactatcaca aaaagtggtt tagtaaacga ataaactata attcgaatac
    14641 taatatattt acaggtgcag caagcaatgc aagtggagat aacgcaaata tggtgcttag
    14701 gtatatagtt tctttttagt taggaggtat ggaagagtgg caaatttaga aattaaatta
    14761 tctgcaaata agagacagcc ttatctacgt caccgtgttg ttggtagagt tggtgatggg
    14821 gggctcacaa caatcaatgt acaacttctt gaggaagatg aaattacacc ttttgtaatt
    14881 aatctaaacg gtactttgaa atttgtgggc gaagtttcaa acggtaacta taccgaggga
    14941 gaaccagaaa taatcgattc gactaatggg ttaattagtt acacgttcac taagtcaaat
    15001 ttcagcacga gtcatcaatt caaacaagca tattttgaat atgtagatcc taacggcaaa
    15061 aaagtaactt ttcagaactt catcatagac gtgttagaac gagtagatat taattcggag
    15121 caagcgaaat actatatttc ttcattggaa aaattacaga gtgaaatgca aaccactttc
    15181 aatcagttca ttagtgataa acaggtccaa tacgatcaaa tctactcgaa atataacgaa
    15241 ttagtaagat tgataaatga atcagataag caagtaaatg atcgtattga taagacaaat
    15301 gatcgtattg atcaaaccaa tcagcaaatc ggcgatctcg gcaagctgaa aaagatgtac
    15361 agtaacagca tcgacttcgg ggactatgat tatagtggga atccgaacct tagcgctaaa
    15421 cttaatgctt caagtttttc tttaggtact ggcgcaacag tcgcggatga taatgatgag
    15481 attgtgttta ccttagatgg cacaaatcaa ctatcgaagt acgctagcaa agcgcaagtg
    15541 ccggtagcag aagggaaaca atatacgatt agttgtgaaa ttatgttaga agatgggttc
    15601 actggcgacc cttcaggaat acgtctgcaa cacgcatatt tgccaggcgg ggttgttgtt
    15661 ttacagacag agacagtacc taaaaatgaa ttgaatacgt ggcagacgct tatcggaacg
    15721 cgaacggtaa aatacacctc tgacgtacca aatgaatggt accctttgtt tagagacatc
    15781 cgaacactta aaccgaccgg taaagttaga ctaagaaaaa ttaagattga agaaggctca
    15841 acagccaccc catatcagcc aaacttactt gatgaccctt actggctagg taaagcgcct
    15901 ttgggtgaga atattgctaa taagtctgtt acgtttccaa tcaaatctag cgcctacagc
    15961 ctataccaag ctaacatgga agaagaattt gttttaggtc aaacctatac aattaccatg
    16021 aaggcaacca aaccacctat ccaaacgttc attgtttaca acgaggatag tggagattat
    16081 agatatggta acttagagcc agtagaaggg ttagttgata catggggtct gacttttaca
    16141 ccgcagaagg ttggagttaa ctaccccaaa cggttaacta ttatccagta tccccaatca
    16201 acaacaggtg catgtcaaat tgactggctc aagatcgaaa aaggcaatac tcgaaccccg
    16261 aatattagtg agtataaata tcgtggtact ggtatgcgtg attcaaacaa tccaaaagat
    16321 tatgtttggg atctagcacc agaatatgtc gaagataatt tggccacaga tattaaaatt
    16381 tctgaaatta ctggtaaagc aaacaattat accgatggga aagtatcgga gattaattcg
    16441 cagttgactg cttcaattaa tgaagtagac accacagcta aggatgctca aacaaaagcg
    16501 aatgctaatg cgactgctat agatgaatta gacaataaga tcgatgaacg cattaatgat
    16561 acagctacta ccacattaac agttacaaac gggaataccg gatcagcaaa gctttatcgt
    16621 gaaggaaaaa cagtttctat atattttgtg gctttaaacg gaaaaagcag tggtggaaat
    16681 gattcaacga tactaacaat tccagaaggc tatcggccac caattagttt tgagcaactg
    16741 gttggctcga tagaccgttc tactttgaac agtgctcagt tatctattgg tgcagatgga
    16801 gccattaaat ggcgaagaaa ctcaagttat ggatcggatt atacctttgc aattacttac
    16861 acgatttaga aaagcgtgaa tcgatatgaa ggcagcatat agaccaattg aaccttacgg
    16921 attcgagcaa atcattgtga atgatgaaga acatttaccg gaagaatgca cagaagtcga
    16981 accaccgatt ctaaattgga aaccgaaatt caattactgg gagggaaata aatgaaaaac
    17041 atttggaaat atggacgtac tggcggagag tacgcaggaa aagtattgga cgacatgctt
    17101 gtatccgttc cttacacaga tcagccaccg cttgaaggaa ttcgtgctga tggcgaaccg
    17161 ttaacaatcg ctgatcaaat gtttgatcct aaattgaatc aatggattat tttagcgaac
    17221 gcactagatc acaacgattt aaacaatctc aaagcaatgt atgagtcgtt agaaaatgag
    17281 aacggcgatt taaaacagat caatgccaaa ctcatgctaa gcgatgtagc aattaaacag
    17341 gaaaatactg cattgaaaga aaaagcggat agtttagcac aaatcaattc aaaaatgatg
    17401 cttgcttcgt tacaaaatag caaagacatt tcagaaatta aagagcaact aaatccagct
    17461 tcaaagggag gtgagtagta tgtttagttt tagcgatgtg aaaatgatgt atgattgggg
    17521 ctgttttact gacgatcaag ttcgactatt cgttccacta tgcattacag acgaagaagc
    17581 agataaaatc attagcaaag aagaaagcgc atcttaagtg atgcgttttt atttaaggta
    17641 aaggagttgt cacatgatca atttagggga atggggaaca atcgcaggat caattactgc
    17701 gattgtttct ttgattttat tagtaataag accagtcact gcatctttct cgaagattac
    17761 tgaaactctt tcaaaagtaa gtcacaattt agatttgctg actaaagatt tagaatcgag
    17821 caaatcagat cgattgatga ttcatgaaga actaaagaaa cacgatgaaa gattagatac
    17881 acatgcagaa aaattggtag aacacacaca acaaattaaa actttattta gagaaaggtc
    17941 tcggtaaaaa agaaaggagt taagaagaaa tgattttacc cgataagtat tatcaagtca
    18001 ttaaatggac agttttaaca gtattgccag ctttatctgt attagtagcc acattaggca
    18061 aagcatatgg atggaatgga acagatatgg cagttctgac tatcaatgca gcagcaacat
    18121 ttttaggtgt tatcactggt gtgtcggctt ataatttgaa aaaataggag gaaacaaatg
    18181 aaaaagaaaa ttactattac tgcgatgagc ctattaacgg ctcttttttt attgccgatt
    18241 aatgggtttg cctatacgat taacaatgaa tttaatttag gtgtaaacga aggtagttct
    18301 caagtagcaa ataatcagta cattttactg catgaaacgg ctaatgaaac agcaacagga
    18361 cgcaatgaag cgcagtatat gcaacgttca tggactagcg cttatactgc ttatattgtg
    18421 ggagacggcg gaattgttta tcaagtcggt caacctggtt atgtacagta cggtgctggt
    18481 tcgtatgcta atgcaaatag tcctgtgcag attgagttac aacacacaca tgataaagca
    18541 acgtttgaga aaaactacaa ggcatacgtt gaattagcta gagattcagc aatgaaatat
    18601 ggtattccac ttacactaga cacaccgtat aatcaaccag ggatcaaatc gcatttatgg
    18661 gtaacacaaa atatttgggg cgatcataca gatccttacg gttatctttc tgaaatgggc
    18721 gtaagtaaag aaaaattagc ctatgatttg gctcatggat ttaccgatga aaatccgaca
    18781 acttcagatg ataaaccagt cattgatcca actcgagcag gtgctgcaaa tcctaccctg
    18841 acagatggaa caaattacgc ccacattgat cagttcggag aaatcgaaaa cgcaaactta
    18901 catgtggctg gttggcacat cgctaactat aaatacgagt atatcttcat tatggattac
    18961 aatactggga aagaattagc tcgagtaaaa gctgatggaa tatatagacc agatgtaaat
    19021 caagcttata atactttagg aaatgttggc tatcatgtat cttttaacat gcgcaacttc
    19081 cctaataaga aagtctatgt aatgatgcgg gcaacgaatg atccagaagg gaacactaaa
    19141 ggcggagcac aagattttca tgataaacgc tggtatttaa atattccgca acgataaaaa
    19201 tagcccctcg tttttgaggg gaagtacata atgcaaattt gtccataact tattgattat
    19261 cttgtaaaaa tgcggtaatt taatagttag tgagaagagg tgcttaatta tagttaaaaa
    19321 agaggaaata gaagcagcat gtaaccaagc aaatgttagg tttattggag aagctttatc
    19381 tggatatcct aagtataaat acttacacaa ctggttacaa agtaaaagtt tttatcttaa
    19441 taaagaaaga tgcatgccta ataaaaatta tagggtttat aaaagaggaa ctattgtata
    19501 tgttgatttt ggggtgaacg tgggttatga gttatctggt aatcattttg ctattgtttt
    19561 aaataataaa gataattcga aaaatggtgt tgtatgtgta gtaccaatct cttcaaaaaa
    19621 gaaaagtaat tatgtatctg taggaaaaat attagaagtt gctagtatta aacaatttat
    19681 aagccaagct gataaattaa aagagaaact taggataatt attttacttt cattaaatag
    19741 aggcatcatt gatgaaagcg atttgaatag ttttattaaa gatattgaag ctaaaggtga
    19801 aaagctttca gtggaagaag tagaaaaacg agctgtaaaa cataatttgg tttgcgagac
    19861 aagggaacaa gtaattaaag aaataaaatc attatctgaa gatatggtaa aatatcagaa
    19921 ggtgtttaat tgctacaaga aatatacaca agaatcctat gtaatgccac ttaatatcca
    19981 aacgattagt aaaaatagaa ttagaagaat taacaagttt gatccttctg gaaatatgaa
    20041 ggcacctgga aatgtcctca atgaagtaga tgaaagttta aaaaaatatt ttacaaagta
    20101 aacgatattt ttgttgacat ttttctgttc gttagttacc atgtagttat agaaggacgt
    20161 aagcgcctat ttttaatgta cacatcggga cgtatgcgcc cacatagaaa cat
//
LOCUS       DADVXK010000044        19970 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.044, whole genome shotgun sequence.
ACCESSION   DADVXK010000044 DADVXK010000000
VERSION     DADVXK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.044"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            68..364
                     /locus_tag="KB909_001521"
     CDS             68..364
                     /locus_tag="KB909_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBB6837547.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(1008..1961)
                     /locus_tag="KB909_001522"
     CDS             complement(1008..1961)
                     /locus_tag="KB909_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6837548.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(1984..2739)
                     /locus_tag="KB909_001523"
     CDS             complement(1984..2739)
                     /locus_tag="KB909_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6837549.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(2736..3695)
                     /locus_tag="KB909_001524"
     CDS             complement(2736..3695)
                     /locus_tag="KB909_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6837550.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(3688..4638)
                     /locus_tag="KB909_001525"
     CDS             complement(3688..4638)
                     /locus_tag="KB909_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6837551.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            4788..5240
                     /locus_tag="KB909_001526"
     CDS             4788..5240
                     /locus_tag="KB909_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBB6837552.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(5329..7596)
                     /gene="gshAB"
                     /locus_tag="KB909_001527"
     CDS             complement(5329..7596)
                     /gene="gshAB"
                     /locus_tag="KB909_001527"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBB6837553.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(7783..8781)
                     /gene="ftsY"
                     /locus_tag="KB909_001528"
     CDS             complement(7783..8781)
                     /gene="ftsY"
                     /locus_tag="KB909_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBB6837554.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(8792..9601)
                     /locus_tag="KB909_001529"
     CDS             complement(8792..9601)
                     /locus_tag="KB909_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6837555.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(9610..13191)
                     /gene="smc"
                     /locus_tag="KB909_001530"
     CDS             complement(9610..13191)
                     /gene="smc"
                     /locus_tag="KB909_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBB6837556.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(13211..13897)
                     /locus_tag="KB909_001531"
     CDS             complement(13211..13897)
                     /locus_tag="KB909_001531"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBB6837557.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(14245..16026)
                     /locus_tag="KB909_001532"
     CDS             complement(14245..16026)
                     /locus_tag="KB909_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6837558.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(16052..16966)
                     /locus_tag="KB909_001533"
     CDS             complement(16052..16966)
                     /locus_tag="KB909_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837559.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(16993..17955)
                     /locus_tag="KB909_001534"
     CDS             complement(16993..17955)
                     /locus_tag="KB909_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837560.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(17955..18899)
                     /locus_tag="KB909_001535"
     CDS             complement(17955..18899)
                     /locus_tag="KB909_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837561.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(18900..19904)
                     /locus_tag="KB909_001536"
     CDS             complement(18900..19904)
                     /locus_tag="KB909_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837562.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
BASE COUNT         5556 a         4283 c         3551 g         6580 t
ORIGIN      
        1 acggattatt aacaactctt cggtagagta aacttatcaa ataaaagact tctttggagg
       61 aatcactatg aaggaatata taaaaaacat ctattttatc gaagaaacac aaaatatcga
      121 gggttcttat attgaagtaa aaacactctt tgtcaatgaa gataaaacca aagcattgga
      181 tatttataaa aaattagctt caaaaaaaac gaatagtttt ggattgatat taagcgagta
      241 taaaatcaaa gcagaagaga gttatttcta tcaattacta aaacggtgga gtaagcttcc
      301 cgccgatttt tatcgaaaaa tgcagatcat caactatcaa ccgcttgctg agacacatgc
      361 ctaaatagag gttgtgaaat cagtgctttg agctaatacc gaaggtcagc tgattgaaca
      421 ttgtttagaa gagattgtga caactgcgat ttgctttgag taataagaac gctggacaga
      481 aaatagcttc tcatattttc tagtctagtg ggcttattgc cgagaagcag cagatggaac
      541 atcgtttaga agagattgtg acaactgcga tttgttttga gtaataagaa cgctggacag
      601 aaaatagctt ctcatatttt ctagtctagt ggacttattg ccgagaagca gcagatggaa
      661 catcgtttaa agaagagatc ggtacaaaat aaaaatatct aaatttaagt tttatctaag
      721 tttcgctttg tacctttgat tcaaatcaaa ggaggcgatc ttgatgctga aaaaatggat
      781 cacactattt tttgccactc cccattctag aatcaacccg tatgatgtag ataatgaatt
      841 cacgttgaaa aaagatttct caaataaata aaaaccatcc gtaaaatcat caatacgatt
      901 ttacggatgg tttttgataa cttctttgag gataggctct tgctatttaa gaatgtaaga
      961 aacattattg ttacatagta tgagagttta atcctctgtt atttatgcta tttaaatgct
     1021 tgattcacat cttcgatcat cagtttcatt gattctaaac cgcccccgct taaataccag
     1081 acatctggtt caagggagat gatctgctga tttttaccag cattcgtttg tgctaccagt
     1141 tcattggcag aaatatcatc tttgctgtcg tctccaccaa tagcttttgt tctgtctact
     1201 acaaataaga tatccggatt tttttccagc acatattcat aagaaacact ttgaccgtga
     1261 gtggatgctt cgatttgatc atctgcttgt tcaaagccaa ataaatcatg gatgaaaccg
     1321 aatctagaac cagatccgta ggctgataat tgcccttcat tcacaagtgt gactagtgct
     1381 tttttgtcag tagcttctgc tttctttttc gtctgatcga ttgcactaga taattcctct
     1441 aattgagttt tagcttcttc ttgcttacca aagatctccc ctaaagcagt gacattttgc
     1501 tggaaagatt cccatggatt tttcgcatct aaagaaagga aaatggtcgg agcaatttga
     1561 cttagatctt tttgaaaatc tctttgtcgg ccagaaatga tgattagatc tggctgaagc
     1621 tgattaattt tttctaagtc tggttctttt attccacctg ctgattctac ttttttatag
     1681 gatgaaagat actcaggaag gctgcttgta gctgctccaa ctaccttatc tccaacacca
     1741 agagcatcca tcgtatctaa agaaccattg tcgaatacga cgactttttc tggattattt
     1801 ggcacctcga tttggtctcc attactatct gttatcgtca atgtagtttc agtttgtgtg
     1861 ctgctttttt ttgtgtctgc ctgactggtg ttgttgctat ttccacatgc tgctaaacca
     1921 aatgatgcta gaatcaagat acctactact aattttttca tctcttctct cctaatgtta
     1981 gttttagaaa taaagacaga atctgcggcc ttcaatctca caaatccgta tgtccatttc
     2041 gtataattca tccaatacat ctttttttat catttcttgg gtcgttcctt gcgtaaataa
     2101 ctgtccatct ttcattgcaa caatttcgtc tgcataactt gcagcaaagt tgatatcatg
     2161 aagaacaata acaattgttt tcccgatttc ttgtactaaa ttttttaaaa tctgcatgat
     2221 ttgaaccgca aaattcatat ctagattgtt caaaggttca tccagtaaaa tataatccgt
     2281 gtcttgcgct agcaccattg caatatacgc acgttggagt tgaccgcctg aaagagtgtc
     2341 aatcgattga tccgctattt cttctaaccc aaggtgttcc agtgattcct gaacgatttc
     2401 ctcgtctttt gtcgtcaatt ttcctttcgt ataaggaaat cgtccaaatt ctactaattc
     2461 tttcacggtg atttggacat ttatttcatt cgattgtcgt aggatcgata attttttggc
     2521 taattcattg gatttccaag cctttacttc gttatggtct aaatagattt cacctgtatc
     2581 ttttggtatc aaacgactga tcatcgacaa caccgttgac tttccagcac catttggacc
     2641 gataaaagca gtcaacttct tttcaggaat cgttaactgt acatctttaa ccactgattt
     2701 tccatggtac agtttattga ccttttgtaa atcaatcata ggatactctt cctttcgcga
     2761 atcaattttg tgacaaaata aattcctccg acaaattcaa cgacgacact cactgttgta
     2821 ttccagccga aaatctgctc tactgcgagc tgtcctcctg tcagaaacag catagctacc
     2881 agaaagcttc cgataaatag ctgaccatga cgataagtag aaaagacacg ataactgata
     2941 tttgcgacaa taaaccctaa aaaagtaact ggacccacaa gagccgttga tgtccctgtc
     3001 aaaagactga cacaacataa aatcaaaaat tcaaaacgat ctgtgtctat cccgaggttt
     3061 actgcttgtt catttccgag atggaaaacg tctagcacat gtcgatatcg aaataacagg
     3121 taccagcagc cgataatgat caaagaagca ggcaaaagat actgactctg gatattgcca
     3181 aagcttgcaa ataatctgcc ttgaagcaaa tcatattcat tcggatccat gatgacttgt
     3241 aaaaaggtac tgacactacc aaaaagcgta cctaaaatca tccctgacat cagtaataaa
     3301 aaaagattcg ctctcatttt tttcaaaaga aagaaaaata acaatagact cagcccgacc
     3361 atcagcccaa cgttcaataa gaaaaaaact gtacctgtct gctgaagcat cgtcactcct
     3421 ccgataaaga agaaaaggac cgtttggaca aggacatata acgactcaag tcccaatact
     3481 gaaggagtca aaaactggtt atgcgtaatt gtctgaaagc tgattgtggc actgctgaca
     3541 gctagcgaga caaggataaa tgcaaaaatt ttcttactcc tcaatgcaca tgcaaaatgc
     3601 cagtttccat atgtatggat cgtcaagtac attcctgtaa caaataaaac aagaacaagc
     3661 ataccaataa aaatagatgg ctttttttta agcatatcgt cgtcccctta tcagaagata
     3721 aaggaagata gccccaccga tgattccaac gatcacactg actggtattt cataaggaaa
     3781 aatcaacacg cgagcgacaa gatcgcaaaa tactaagaac aaactacctg ctaaagcagt
     3841 tacgccaatt gttttgtgca cttgatctcc atatattcta gagacaagat tcggaatgat
     3901 cactccgata aaaggaatgc ttcctaccat gatcaacatg actgcactag ccaatgatac
     3961 taagccaatg cctaaaaact gcatcttctg gtaatctatt cccagattta ctgcaaacga
     4021 ttcgcccaga ccaatgatcg taaatcggta agcaaatagc caaaccaaga gcaacaatgg
     4081 aacaacagca tacaataact cataatttcc tcgtatcaca gtcgcaaaat tcccttgaag
     4141 ccatgaagtc atattttgta ccaactggaa ttgataagca aaaaaagtag caactgaacc
     4201 aatgatattc cctaacatga ctccaatcaa cggaagcatc aattgatttt tctggaggaa
     4261 caatcgcgta agggataaaa aaagcaatgt tcctgcaaaa gcaaagcaaa atgctgtcaa
     4321 ggatcggaca atcaaggatg caccaggtag gaaaatcata gccactaaaa tacctaaacg
     4381 cgcactatcc atcgtgcccg cagtcgttgg tgaaacaaat ttattttggg tcaaatgttg
     4441 catgatcaac ccacaaatac tactggtcgc tcccacaagg atcaaacaaa tcgttcgtgg
     4501 caaacgagtc actagcaaga tttgtaagct ttgcccatct aactggagca gttctgacaa
     4561 ttgtacattc gatactccga tgaacaatga aatactactt aaaataacta ataatgctac
     4621 tagtcgtccg tagcgcatcc aatccacctt tctaattgag aatgattttc attcttattt
     4681 taagtgaatc gttgaacaaa agcaaccgct ttttcatatg ttttaggtat tattgggaat
     4741 atgctataat cgtaagaaag acaaagagaa gaaggagggt attttttatg gcacaagatg
     4801 atgtaaaaag ccatttggat aagggacttt atggtacacc tttagtgaac cctgaagaac
     4861 agcataaata tttagggaca ttcagggaac gctgctatct tagtatgact gttgctgaaa
     4921 tgatccaacc aaaaaacaaa gaaaactttt taaaagaact caaaaaacat ccagatgctt
     4981 ccatactctt gaatggggct ctaccccttt ctgtccaaaa ccaatatatc cagctagcaa
     5041 cgaaaaacaa tagccgtttc actgtagtca acgattacgt cactgcaaat cctgaggaat
     5101 tcggattgct cttaacagca aaagaagcag taaatgaacc tgtgattgat atcgaaaaaa
     5161 aatacccaga agaaaactct tcgccagctg aaaaagaaaa accaaaaaag aaaaaaagct
     5221 tctgggatcg tttattttaa aacgaaaaaa cacataaatt tttacatgca aaaaaagctt
     5281 ttgatcagat tgacatcaaa taggacaatc tgtcaaaagc tttttctttt aaaatacttc
     5341 aggatataac aatttcaata cattcatcgt caatcttctg ccttttcctg caaaaggata
     5401 aacatgcata tgcatggctg gattgaaatt tgcttcgatg atcccatatg cttttttatc
     5461 agttgtagga tcgatttctt tatctggtat aatcaaatcg ataccactaa tcttagctcc
     5521 tagtgcttct accgcagaaa cggcgatttt tttgtaagct tcagaaaatt catcagtcat
     5581 atcgatcgaa tcaccacctg tactgatatt tgagttctcc cttagataaa caatttgatt
     5641 ggcttgggga actgattcga tcgtcaaccc ttgttctttc aacatcaatt gttctaattc
     5701 acctaattgg atcaattcta aaggtgcacg atgattcgtt ccacgcaaag ggtcactatt
     5761 tttttcttca acaagttctt tcactgttcg gatactgtca ccaataacat tagcagggac
     5821 tcgcaacatg atggcttgga cttctccgtc gatcacaaag aaacgatatt ccgttcccgg
     5881 cataaattct tctactaaaa ccgaactgtc ttcacgaaaa gcaatggcta aacctgcttg
     5941 ataatcttcc agactagctc cttccttgaa aatcgtgata cctaacccgt aattggttga
     6001 tttaggtttg atcacaaatg cctgctcggc aaatctcgga taagctttta ccgcttcttc
     6061 catggatgaa aattctgcgc ctcctggtac ccggaaccca gcttctttta agactttttt
     6121 cgttactgtt ttgttttcca tgataagtgg gacgatatag ctgtccttac ttgtcatgtt
     6181 tgcatttttc acatattcta catggtcttg gaattgcaga cgcaaaaatt gatccgactc
     6241 atctaatact ttgacttgga cacctttttg gatggcatcg aacataaata tctgagtaga
     6301 aagttccatt tcgcgaaaac cggccaactg atagggacgt tcatggcttt ctttataata
     6361 ttgatgtccc aatgccacag caacttcttg ctgactcgat agctgtgctt cttgatagag
     6421 tttcgctgct aacgtttgtt caggatgatc catttgagtc aatgcttcct ctactaaata
     6481 aagagaatcc aaccaatcca attcaaccag catttgcttc attccttcaa gaatttctct
     6541 accttcttga tgaaattctg tttgatctga tggttgttct agtgctactt tgttatttcg
     6601 agtcgtacct tctgctaccc attggtcaca gtcttctttt tcttctgtcc ataacatgta
     6661 catcaggaat aattgtaaga accgaacttg ctctggattg atacccaatc ttgcataagg
     6721 attcaaatcg atattccgca attcaatata acgaacacct gttgttgcta aatctgcgac
     6781 tttctttccg cctcggaaac gaagcggtgt ataaaattct ttctcctccg aaagtttccc
     6841 ttcttcgatc attcgctcga tatctgctaa atactgtttc atagaagcat aggaaacttt
     6901 cacatttgga tgattcgtat agcccagcgc actgttgcga atactgcgaa caggttcttg
     6961 cggatgtgat tcatctaaaa agtagttctt ctcactcatt ggtgaagcac cgaataaata
     7021 agtgatcatc cagcgatagc gcataaagtt tctcgctgtt ttcaaataaa gttctgtttt
     7081 gaattcggaa aaatcttgaa attcttcctg atggctgaac aatgttctta gcaactcatc
     7141 gccaaattca aaattgaaat gaataccgct taccatctgt tttcgcttcc cgtatttttt
     7201 tgctaaataa cgtcgataca agacatcttc gaaatttttt aattttgcaa taatgatctc
     7261 ttcgtctttt tccggtaagg caggtggcat acttaatggc cagatcatct cttctttcgg
     7321 tatagaacga gcagtcacat cataaacagc agcgagatac tgaaataatt cgggaataga
     7381 atcggtaaca ggggtgatca tctctgtttg tgtttcgcta aaatctgttt ggatataggg
     7441 gtgataggat cgatcgccaa agattgctgg atgatcggtt tttgctagat ttcctgcaag
     7501 atcaacccgc tgtccttccc gttctatacc aaatcgagct tggtcgataa aagggcgcgc
     7561 attgacatgc aataataatt gcttaaaatt catcattaag tgacctccaa ttcatatgaa
     7621 tctaattata atcaaaaagt ctaagaaaaa gaacgaaatt gtttgagaac cgcttacaaa
     7681 taagtataaa aatgaaggca tcaaaaacac agctatgtta aaaacaatca ttcaaacaag
     7741 gagctgcaac ttttgtcaca gctcctgctt tttagacatg ggttattctt cttttagtaa
     7801 tcctttgaac aatccaacga caaaatcatt tggatcaaac ggctccaagt catcgattcc
     7861 ttcaccaaga ccgaccaatt tcactggtaa atgcaattca ttacggatag caagtacgat
     7921 accgcccttt gctgtaccat ctaattttgt caaaacaaga ccggtcacat ctgttgtttc
     7981 tttgaattgt tttgcttgaa ccatcgcgtt ttgaccagtg gttgcatcta atacaagaag
     8041 tgtttcttgg ggtgcttctg gtaattcccg ctggattact cgttttattt tttctaattc
     8101 gttcatcaag ttcactttat tttgcagtcg gcctgcagta tcaactagta aaacatctgc
     8161 ctgctctgtc tttgctcttt ccaaagcatc gaatacgaca gctgctggat cgcctcctgc
     8221 attgccacga acaacttcaa caccagcgcg ttcgccccag acaactaact ggtcgattgc
     8281 tccagcgcgg aaggtatctg ctgctgccat caatactttt ttaccttcgt ttttgaactg
     8341 atgggcaagt ttaccaatac ttgttgtttt ccctacacca ttaacaccga caaacaaaat
     8401 aactgttagt ccgtcttctt ggatatttag ttcatttact tcattgattc cttccgcttc
     8461 atagagatcc acaagtttct cgatgatcgc attttggact tctgccgatt ttttcgcatt
     8521 tctgagtttc acttcttgac gtaatgcttc ggtgattcgt atcgctgttt caaaacctac
     8581 atctgcaccg ataagtgttt cttctaattc ttcaaaaaag tcttcatcga ctgttcgaaa
     8641 attggcaaac aactcattca tccgttcacc aaatgtttta cgcgtctttt ctaaaccctt
     8701 gtcgtacttc tcctgtactt caacttcttc tgttttctct tcgccagtaa aagcacgctt
     8761 gattttatca aaaaatccca tttgactccc cctactctaa tacaaatttt tggatcactt
     8821 tggctacgcc attttcttca ttgctggctg tcacgaaatc tgctgcttct ttgacgaaag
     8881 gcacagcatt ctccatcgct acgcctagtc cagcatattg gatcatcggt aaatcatttt
     8941 cctcatcacc gatcgccatg atttcttctt gtttcaaacc aagatctttt gccaataaag
     9001 aaataccata agcttttgta acaccttttg gcataaattc caaaagcata cttcttgttt
     9061 tgatgatctc atacatttca tggaattctg ctggtatttc tttgatttta ggatctaatt
     9121 cttcttggtc ataagcgatt actgccttat taagcacaaa ttcatctgta atatcgctta
     9181 tatccgctgg ttggaattgc agcagcttat tcaacacatt gtacaaggat tgcttccttg
     9241 gggcactagg cagctgtaaa accacattgt cagacaaaac atctagtggc agatccaatt
     9301 gctgagccag tttgtataag cgttggatat ctgatacttc catcactttc ttttccatga
     9361 tttcaccagt atcatttttt tgtaccaaac cgccgttgaa agtgatgctg tagtcacctt
     9421 catctaccag tcctaattct tgcagataat gcgccatcgc agctaagggg cgtcctgtac
     9481 atagaacgat cttgacccct tgctgttttg cttgtgctaa tgcttgttta ttctcatctg
     9541 aaatcagctt ttgttcattt aataatgtac cgtccaaatc gattgctact aatttgatca
     9601 ttttcgttcc tacactttcg tttcgttgat tttcgcctct tcattgatat cttccatccg
     9661 tacagaaacg atttttgata caccggattc ctgcatcgtc actccgtaca gtacatctgc
     9721 tgcgaccatc gttcctttgc ggtgtgtgac tacgataaat tgtgtgtcat cttggaaatc
     9781 gctcaagtaa cgaccaaaac gtttcacgtt ggcttcatct aacgctgctt ctacctcatc
     9841 taagatacaa aacggaacag gacagacacg gataatggaa aagagcaacg cgatggctgt
     9901 aagtgctcgt tctcctccag aaagcaaact tagactttgc agttttttgc caggaggttg
     9961 tacttcaatc tcaatacctg ttttcagcaa atcagttggt tccgtcagta ctaattcagc
    10021 tttaccgccg ccaaacatat ttggaaagac aattttgaat tcttgacgga tagcttcaaa
    10081 tacttctttg aatcttgtcc gcacttcatc atccatctca tccatcgttt caaacaattg
    10141 gtttttcgct gctaacagat catctcgctg tgttgctaag aatgtatgtc tttcactgac
    10201 ttgttcgtat tgttcgattg aatttaagtt tactggtccc agtttttcaa tctgttcttt
    10261 taaggatgaa acctttgttc tactgtcttc gatatcggtt gtttcttgat agtcttggga
    10321 agctttctca aatgtcagct gatattctga ctgcagatag gtcaaatgat tatctaaaat
    10381 catttcagct cggtcttttt ggacttctaa tttggattgt tccgacagtc gtgctttttg
    10441 ctcacgatta cgctctgcca agactgcttc aagcttatcg atctcctttt gccttctatc
    10501 tcgctgctct ttggcttttg ccaactcggc ttttaatgtt tctcgctgag cagataattc
    10561 gttaatttgt ttttccaaac tttcttctgt gacttcatga tcagaaaagt ctgctgtcaa
    10621 tgtcgccaac tgcttttcta tcgcttcttg acgttcggtt gcctctgctt tttggactcg
    10681 ggcaccgcgg agctggatct gcagatgatt aaactgctct ttcaagacag caagatctgc
    10741 ttgttcttgt gctttttgac tttgtacttg tgctcttctg gcttccatct ggtcgctttc
    10801 ttgacttaac gatttgattt cttcgtcgat tttttgtcgt tgcgattcaa gatctgtttg
    10861 tttgtctttc aattcgttcg tttgcttttc gtaatcttcg ataaactgct gcagttcacg
    10921 tgtctcaaaa gttgagattt gcttttcttt ttcaaaacgt tcaagttcat ttatgatgtt
    10981 ttgtagctga tttgtcgctt cttgttcttc aaaacgtaat tgttcgcctc gtgtacgcaa
    11041 aacttcttgt tcttcggcta aacgagctgt ttcttgttgc agctcctgaa cttttttttc
    11101 ttgtgcttgg agttgtttat ctgcttcttc aaattcacta gtcaactgtt tcaattcttg
    11161 attttgtaca aacaaactgc cttggtttcc tcgtttattc gctccacctg tcatggatcc
    11221 tccggcattc atcacatcac cttctaagga aaccactcga tattgatagc ggatcgtttg
    11281 cgcgattgca ttggcactag ttaagtcttt ggctaaaagg atcgttccta gcaggttttg
    11341 aaccacagtt tggatttgat cgggataact gacttgttca ctggcaatcc ctataaaccc
    11401 ttctacagct gctgcttgtg tcaatatatg agccggtaat tgtcttggtt tgattgtcgt
    11461 cagtggaagg aatgttgctc ttcctcctct ttgctgtttc aaatacgtga tggcttgccg
    11521 agcatctttt tcattttcaa cgatgacatg ctgggctgcc ccacctaaag ctgcttcgat
    11581 agctaacgtg aaatctgcag gaacatcgat cagttcagcc actgctccga caatacccga
    11641 aagctgctgt ttatgctgca agaccaatcg aaccccttgg taaaaaccaa aatagttttc
    11701 ttggatttct tgaaggcttt tcttacgagc acgtagctgc tggacttgat tcattaattg
    11761 atacatttta ggctgttctt ttgctaatgc ttcttggaac tttttcccgt tttgttggat
    11821 catttctaac ttctcttttg tttcagttaa agatgatttt agctgcgcct gcttttgtgt
    11881 caattcttct ttttgtaaga tcaatcggtc tactgatgct tctacttccg attgcttggc
    11941 taacgtctgc ttgctttttg ctgtttcttg tatatattga cgttctagat acttcagttc
    12001 gtttcctaca gctgcttgtt cttgcatcaa atcaacatat tgatctctta attctgccaa
    12061 taattctttc gttgattttt ggtatttttc taattcttgc tgtgttttta tgagatttgc
    12121 ttcagctttt tggatctctg tttctttttc tgctgctgct ttcatcaagc tttcttgaag
    12181 cttttcaaaa tgtttaacct ttttttgtgc ttctgctaat gaagtttgat attcttgcga
    12241 gcttttttgt gtatgctttg tccgctcctg caaaacatct ttttgtcctt ctgtctgctt
    12301 cagtttttcc gaaagatcta ataatacttg ctgatttttt tcgatcagac gatcggcttg
    12361 cgcattttct ttacgctgct tcgccaaaat ggattcttgt tcttggatcg actcagatag
    12421 tttgcctaat tctagattga atttcgcaag ctgtgcttgt ttgttgtccc aatctttttt
    12481 tgctgtcttg atttcagcaa ccatcaaaga gacatcggtt tgagtcagtg tttcttttag
    12541 ccgtaaaaac tcctttgctg cctcactctg ggcggccaaa ggagttaact gttcttccaa
    12601 ttcgtggatg atgtcttgga cgcggctgag gttgtcttct gtttcaaaaa gcttctgttc
    12661 tgctttcttt ttccgctgct tgtatttcaa gacaccagct gcttcttcaa agatcccacg
    12721 acggtcttcc ggtttactac tgaaaatcgc ttctactttt ccttgagaaa tgattgagaa
    12781 cgattctttt cctaatccag aatctaagaa caattcttgg atatctttta atctgcagct
    12841 ttgtttattg atgaaaaact cgctttcccc agtccgtcga taacggcggg ttacactgat
    12901 ctcattgtac tccaatggca gataatgatc actattgtct aaaatcactg tgacttctgc
    12961 aatattcagc tgcttacggg tatcggaacc ggcaaagatg atatccggca tttttccgcc
    13021 tcgcagactt ttagcagatt gttctcctaa tacccagcgg atagcctctg taatattgct
    13081 ttttccgctg ccatttggtc caaccactgc tgtgacgcta ttttcaaaat caatgactgt
    13141 cttgtctgca aatgatttaa aaccggctat ttcaattcgt ttcaaataca aagctttccc
    13201 tcacttactt ttacagtgct gccaatgcat tttccgccgc agcttgttct gctaattttt
    13261 tcgatttccc ttgtccagtg ccaatcaatt gatcatctac ataaacttcg atccaaaata
    13321 ctcgttcatg agctggacct tcttcattga tcaatcggta ttcgattgat acatcacctg
    13381 atttttgcaa gacttcttgt agttttgttt tatgatccat ctcatgtgaa aaagcacctg
    13441 ctttgacttt aggaaaaatc actttttcga tgaatgcatg ggtcgtgtcg aatccctggt
    13501 caagatataa cgcgcctaaa aaagcttcga ataggtcgca aagcaatgct ggtcgcgtac
    13561 gtcctcctga attctcttct cccttgccca acaaaacata ttgatcaaag tgacattctt
    13621 tggcaaattt cgacaagctg tcttcgcgaa cgatcgcagc tcgtgttttt gtcaattttc
    13681 cttctggcaa atgaggatat aaacggaata aatactgaga aaccatcagt tctaaaacgg
    13741 catctcctaa aaattcaagt cgctcattat ccgataattg cagattgcga tgctcattca
    13801 cataggatga atgggtaaaa gcttgttcaa gcaaatttag atcgtgaaaa acgatgttat
    13861 agttttcttt tagttctttt gtcagctggt tgtccatttt ccacattcct tttatggata
    13921 ttttttcgat acttccttat tatactggtt ttttgtcaaa tttgaaatgg ttcggtcaaa
    13981 aggtaagtaa agctttaata atcctagtga ttgacgagaa gttgtgaaaa attcgtttag
    14041 tttcgagtat gaagaaaaaa ttttgtgaaa atggctttcc atatttttgc ataaatttga
    14101 cttaataccg agaaactgga ctttgaacac cgtttattgg agaagtcatg aaatcagcgc
    14161 cttgacctga atattagaga aataaacaga aaaatatcaa aaaaccgaaa aaggacatcg
    14221 ccctttttcg gtcattttta gtgattatga acgtgaatct gctgtaacag aaacatttgc
    14281 ccatgggttt ggtacatcat aagaccaatc ccagtctttg acacggtcgt tgactggcaa
    14341 tacttcatta cggaacaacg ttggaatcgc aaatgcttct tcaaatgcat attgttgcca
    14401 tttttgatat gcttcttttt ggtactcttc atcaaatgct ttgcttgaac tgatatcgtt
    14461 gatcaatttt gtattttctt ctgattcata acgagtgtag ttgaacgcag catttggtcc
    14521 ccatagtcca cttggatttg gatcagttcc tgtattccaa gcagcttggt aaacatcaat
    14581 ttcaggatca tcgttttcta atttatcata gaaagaattg aattcgatca gacgacctgt
    14641 tgtgtattgg acatccaaac caatttcttt ccattgttgg atatagtaat ctgccaatgg
    14701 ttgcgctgtt tccccaccgg acatcgaagc aaagttgatt gttagtttat ttccatcttt
    14761 gtcttctctt aaaccatcgt catccacatc tttgtagcca gcatcatcta atagtttttt
    14821 cgctttgtct agatcttgtg tgaatccttt catctcatca tcatggtatg actggaatac
    14881 tggaggaatc aatgaagtcg cattgcttct caaacctgca tagaaacgtt cacctactgc
    14941 attattatct aatgcatagc ccattgcttg acgtaatgat ttatcagcca tttttgaatc
    15001 tggattgtat tccacactct ttgtatctgc attccattta cctaacttga atcctagata
    15061 agtataagaa gtttgttcac ggcctaagtt tgtatagcca gcaatttctt tataggtatc
    15121 gtaagtatct gttggcattt ggaaaatcat atcatataat ttagagttca atgcttcagt
    15181 tgcacttgcc atcggtacag atttcatcgt gatctttttc aatttaggcg taccattcca
    15241 gtagtgctcg tttggcaagt attctactga ttctcctgca acgatattac tcatgtaata
    15301 agggccaaaa gtcactggat ttttacgtac ttgatcgctt gattccatat ctttgattgc
    15361 tacaccttct aacgtatgtt ttggtgctgc atatgaccag ataccaccac ccgattgaag
    15421 catgcttggg tttacttctt tatattcgat ttcaactgtt ttgtcgtcta tttttttgat
    15481 tccggagatt gtgtcggcac ttccatcatg atattcttcc atacctacga tgttacggaa
    15541 agtgtcgtca taacggatac cagtgtaatc tttattccca atgatttcgt aagggaaaat
    15601 cacatcgtcc gccgttacat cttcaccatc tgaccatttg acgttgtctt ttactttgat
    15661 tgtcgctttt ttcgtatctt catctagatc aagcgttgca gctccgtcgt ctgtgattct
    15721 gaaatcgtca tcgtttgcaa atagcggttc atgagaagga gccataaaag ctgcatcata
    15781 tgaatcttgg taaaactccc actggaacaa tcctttaaac tgactgtccg ttgcgaccgc
    15841 agcttctaat tcgccgtctt cgattgcatc atcattattt tttgttgcaa ttggaaaagt
    15901 taattcctct ttgttattgc cgttgcctcc agagttgttt ccagaggtat ctgtacctcc
    15961 gcccccgcat gctgcaagaa cgacagcaga catcagcgct gcaaatccaa aaatcgtttt
    16021 cttcattcct atttccccct tcgcttctat actagcctaa ccgttggcgc gcatctgcag
    16081 aacgcttgaa tgcttgtcca acataattga tactcaacat caaaactaaa ataaggattg
    16141 atgcgggtaa ccagatccat tgccgattca ctaagacttc tccgttactt gcataaccga
    16201 tcaatgtacc taaactaggt acatttgccg gcaagccgaa acctaagaaa gtcaaagttg
    16261 tctcgatacc gatgtttgcc gcaaagttca tcgtcaaatt agtaatgatt aatgaactta
    16321 gattcggcat gatttcgcgg aacatgattt taaaatcatt ggttcccatt gtttttgagg
    16381 cactgacata atctcttctt gcttcagata atgtcttgct tcggaataat cgggctttag
    16441 ctacccaata aaatgcactc atgatgaata taaaggacca gacattgtat ctggaaataa
    16501 tcgatacgaa gacgataatg atcagcatga tcggtagaat catgataaaa tcaacgatcc
    16561 gcatcaagat gttgtcaatg atccctccgt agtagccaga gatgatccct aatccaaccc
    16621 cgatgatcga agtaaggatc gtgatcgcaa atccgatcgt aacagagttt ctagcaccta
    16681 tgatcaattg tcctaataca tcacgtccgc cttcatctgc tcccagaatg aacttttgtc
    16741 cttgtgtcga aactgttcct ggtgcagcgt atttgtcgaa gatactaaca tacatcactt
    16801 tgtcttgatc ggtcagcatc gcaccgataa agatcactaa taataaaacc actagcaaac
    16861 ctaatgaaaa aatagcaatt ttatcttttt taaattctcg agcaatcatt cgtatcccca
    16921 taggaggaat actttcttga actgctgtat tgtttttttc actcatcgat ccattctcct
    16981 ttctgattgg ttttattgaa tccgaatacg cgggtcaacg atactcatga tgatatctga
    17041 aagtaatgtc cccactagcg tcgcgattcc taaaatcaat actaaggatg tgatcacggt
    17101 atagtcccgt tggccgatgg aatcaataaa tagttttccg actcccggat aaccaaaaat
    17161 cttttcgata actacagaac cagcaatcaa cgaagtgatt tcatacccca tttgagaagc
    17221 catcggcaac gctgcatttc ggaaaatatg tcgactgaat actttattcg tcggtacccc
    17281 tttggaacgg gctgttctga caaaatcgag cgatttcgaa tcgattactt cacttcgcag
    17341 atattggatt gtgacggcag tcgccaaaaa tgcttgggta attgatggta acagaatata
    17401 tttcaaacgg tctatccatt gagtgataaa tccaccttgc aaacctagtg tttgtgatcc
    17461 acttgttggg aaccagccta aacgataacc aaaaacaaat agcatgatca agccgaagat
    17521 aaataaagga acagcaaaac taaagaagtt gtagattacg acaatcttat ccaagattga
    17581 attttgatac cggccagcaa gcatccccag aggcacagca atcaaataag taaggacaac
    17641 tgtcaagatc gatagatata aagtgttgat gatccgttcg ccgatcaagt cagcaacaga
    17701 gcgtttgtat aagaaacttt gaccaaaatc gccttgcaaa gcatttccga tccaacggaa
    17761 gtactggaca taccatgggt cattcaagcc agctgcttgt cgcatctgtt cgatcactgc
    17821 cggatcctga tttggattga tcaaaccggt aaatggatcc cccggcatcg cttgggctaa
    17881 taagaagatc agaacactta aaataataac ttgcgggatc atcaataaaa cacgtcgcag
    17941 aatcgttttc cacattagct tgcacctcca tctttcaacg ccactttgtg tgtagttgtg
    18001 atcgtacgca aatcgtagac tcgaccagtc gcatcatagt attctttttg gttttggata
    18061 tactcttgtt ctactcttcg tcgattttct ttgtggcttt ccctattttc tacatcgatt
    18121 tgcggaatag ctgaaagcag acgtttcgta tagatatgtc gcgggtcatt ataaatgtct
    18181 tctcttgtac cgatttctac aaatcgacct ttgtacataa ttgcgatatt gtcgcacatg
    18241 tgttttacta cacctaaatc atgtgaaatg aataaatagc tgaggccgta ttcttgctgg
    18301 attcgtttca tgaaattcaa tacttgcgct tgaacagata gatccagagc agatacaggt
    18361 tcatcggcta cgatcagttt tggattggta gcaacagcac gggctactcc tagacgttga
    18421 cgttgtccgc ctgaaaattc atgaggatat ttatatagcg catcttccgg catcccaacg
    18481 atatctagca gtccttttac ctttttcttt tcttcttgat cgcttaaccg ttcaaaattt
    18541 cggatgggtt cagcaatgat atccaacact cgctttttag gattcaaact ggacattgaa
    18601 tcttggaaga tcatctgcac atccttgtta taacccattt ttttgcggtt gcttcgcttc
    18661 gttacatctt ttccttcata catgatttgt ccggctgtta ccttttctaa tcccacaacg
    18721 gcttttcccg tagtagattt tccagagcca gactctccca ctaaaccata tgtctttcct
    18781 ttttcgataa taaaatccac accatctaca gcatatacat gatccgttac tcgattgaag
    18841 aatccactgc gaatagggta atgaactttc aggtctttga ttgtgattaa ttctgtcatc
    18901 tacacctctc ctttttcgtc tctaaagtgg aaatgcttat agcaggagca acgtaccaag
    18961 tggttcggtg cgacttcatg aaggataggc tcttcttcat gatcgcttgc tggtatccat
    19021 ggaatacgtg gtgcaaaccg acaaccttta cgaggcatgt ttttcagaga aggaacgaca
    19081 ccttcgatca catggagttc tgcatcatga tttccttctt gtggtataga gttcagtaaa
    19141 gagcgtgtat aaggatgctt aggatgatca aacagttctt ttacacctgc tacttcaacg
    19201 aactgtccgc catacatcac tgccactcga tcagccattt ctgctacgac tcctaagtca
    19261 tgagtgatca agatgatccc tgtttttgtt tcttcctgaa ggtctttcag taaatcaaga
    19321 atctgtgctt ggatggttac atctagggct gtcgtcggtt catctgcaat gacgattgga
    19381 ggtttgcagg cgattgcgat tgcgatgatg acacgttgtc tcataccgcc tgatagttca
    19441 tggggatatt ggcgtccaac tctcgcagga ttaggaatcc ctacttgttc tagcaattct
    19501 agtgcacgag cttgacgctg ttctgcattc atctttgtgt gataggaaag tccttctttg
    19561 atctggtctt cgattctcat gagaggattt aatgcagaca acggatcttg gaaaatcatt
    19621 ccgatatcat ttccgcggat tttattatag agcgtttcgt tcaggtcgat taaattcaga
    19681 tcgttatata aaatctcacc tgtaattttt gtgttattag gatcaagtaa tcccataatc
    19741 gtagtagcca aggtactttt cccgcaccca gattccccaa cgattgctaa aatctcgttt
    19801 ttgtctaaag taaatgaaac gtcatctact gcatcgtaat agtcatcttt gagtcggaat
    19861 cctgtatgta ggttctgaac ttctaataat tggttatcgg acaatcgaat acccctctct
    19921 gcttcctaaa tggaagtttt tcttaataaa aaaggacatt acacagaata
//
LOCUS       DADVXK010000045        19633 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.045, whole genome shotgun sequence.
ACCESSION   DADVXK010000045 DADVXK010000000
VERSION     DADVXK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.045"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="KB909_001537"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="KB909_001537"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBB6837563.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="KB909_001538"
     CDS             complement(1172..1867)
                     /locus_tag="KB909_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBB6837564.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="KB909_001539"
     CDS             complement(1880..2596)
                     /locus_tag="KB909_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBB6837565.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="KB909_001540"
     CDS             2926..3534
                     /locus_tag="KB909_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBB6837566.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="KB909_001541"
     CDS             3859..4182
                     /locus_tag="KB909_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6837567.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="KB909_001542"
     CDS             4364..5734
                     /locus_tag="KB909_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBB6837568.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="KB909_001543"
     CDS             complement(5864..7165)
                     /locus_tag="KB909_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6837569.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="KB909_001544"
     CDS             complement(7519..9477)
                     /locus_tag="KB909_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBB6837570.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="KB909_001545"
     CDS             complement(9654..9920)
                     /locus_tag="KB909_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6837571.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="KB909_001546"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="KB909_001546"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBB6837572.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="KB909_001547"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="KB909_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBB6837573.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="KB909_001548"
     CDS             13264..13827
                     /locus_tag="KB909_001548"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6837574.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="KB909_001549"
     CDS             complement(14080..14601)
                     /locus_tag="KB909_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBB6837575.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="KB909_001550"
     CDS             complement(14604..15446)
                     /locus_tag="KB909_001550"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBB6837576.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="KB909_001551"
     CDS             complement(15439..16164)
                     /locus_tag="KB909_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBB6837577.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="KB909_001552"
     CDS             16340..16636
                     /locus_tag="KB909_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837578.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="KB909_001553"
     CDS             17204..18796
                     /locus_tag="KB909_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6837579.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="KB909_001554"
     CDS             18809..19549
                     /locus_tag="KB909_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6837580.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5619 a         4028 c         3725 g         6261 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagccattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaagtaaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgagatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaa
//
LOCUS       DADVXK010000046        19453 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.046, whole genome shotgun sequence.
ACCESSION   DADVXK010000046 DADVXK010000000
VERSION     DADVXK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.046"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(67..807)
                     /gene="truA"
                     /locus_tag="KB909_001555"
     CDS             complement(67..807)
                     /gene="truA"
                     /locus_tag="KB909_001555"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6837581.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(998..1633)
                     /locus_tag="KB909_001556"
     CDS             complement(998..1633)
                     /locus_tag="KB909_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBB6837582.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(1780..3021)
                     /gene="sstT"
                     /locus_tag="KB909_001557"
     CDS             complement(1780..3021)
                     /gene="sstT"
                     /locus_tag="KB909_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBB6837583.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            3219..4217
                     /locus_tag="KB909_001558"
     CDS             3219..4217
                     /locus_tag="KB909_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837584.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            4230..6248
                     /locus_tag="KB909_001559"
     CDS             4230..6248
                     /locus_tag="KB909_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBB6837585.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(6308..7024)
                     /locus_tag="KB909_001560"
     CDS             complement(6308..7024)
                     /locus_tag="KB909_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6837586.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(7251..7793)
                     /locus_tag="KB909_001561"
     CDS             complement(7251..7793)
                     /locus_tag="KB909_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6837587.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(7798..8025)
                     /locus_tag="KB909_001562"
     CDS             complement(7798..8025)
                     /locus_tag="KB909_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6837588.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(8104..9984)
                     /locus_tag="KB909_001563"
     CDS             complement(8104..9984)
                     /locus_tag="KB909_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6837589.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(10173..10787)
                     /locus_tag="KB909_001564"
     CDS             complement(10173..10787)
                     /locus_tag="KB909_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837590.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            10929..11489
                     /locus_tag="KB909_001565"
     CDS             10929..11489
                     /locus_tag="KB909_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6837591.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(11794..12108)
                     /locus_tag="KB909_001566"
                     /pseudo
     CDS             complement(11794..12108)
                     /locus_tag="KB909_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(12362..13997)
                     /locus_tag="KB909_001567"
                     /pseudo
     CDS             complement(12362..13997)
                     /locus_tag="KB909_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14436..15305)
                     /locus_tag="KB909_001568"
     CDS             complement(14436..15305)
                     /locus_tag="KB909_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6837592.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(15325..16446)
                     /locus_tag="KB909_001569"
     CDS             complement(15325..16446)
                     /locus_tag="KB909_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6837593.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(16448..16843)
                     /locus_tag="KB909_001570"
     CDS             complement(16448..16843)
                     /locus_tag="KB909_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6837594.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(16862..17668)
                     /locus_tag="KB909_001571"
     CDS             complement(16862..17668)
                     /locus_tag="KB909_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6837595.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(17661..18449)
                     /locus_tag="KB909_001572"
     CDS             complement(17661..18449)
                     /locus_tag="KB909_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837596.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(18463..18939)
                     /locus_tag="KB909_001573"
     CDS             complement(18463..18939)
                     /locus_tag="KB909_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837597.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(19011..>19453)
                     /locus_tag="KB909_001574"
     CDS             complement(19011..>19453)
                     /locus_tag="KB909_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6837598.1"
                     /translation="DMILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQL
                     TILNPTKLLERVSDAIYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYF
                     NETSEEFQKFQTHFKQSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
BASE COUNT         6139 a         3914 c         3028 g         6372 t
ORIGIN      
        1 tcatacatta tttaacatcg atatttatac tgtgaaacat gcgtttcatc cattatcaaa
       61 gtatttttat cgataataaa cttcatccaa aaacagacct tgtgcaggga cggtttctcc
      121 tgcatgttgc cgcactttgc tttcaaatat ttcatcgatt gtttctatcg gcatggcacc
      181 tgtgccgatt tctagtaatg tccccatgat aatccgcacc attttatata agaatccgtc
      241 tccgacaaaa gtaaaatgaa gcatttctcc ctttcgttcg atagataatt catcaatcgt
      301 acgcactgtg gatttttttg attttttcaa tgcagaaaaa ccaatgaaat catgtgtacc
      361 cactaatttt tcgcaagctg cattcagctt gtccatatcc aactcttgag ggaaataaaa
      421 gctgtggttt cgctcaaatg ctgaaggaat cacgttgttc caaacataat agctgtattt
      481 tttgcccacc gcattatatc ttgaatggaa gcgctcaggc atttcttcga ttcttttgat
      541 gacaatatcc cgcggaaggt aacgattcat aaagtcgatc atttctgcca gtccaatttc
      601 tgtgtttgtt ttaaaatttg ctacttgtcc tcgcgcatgg gtgccagcat ctgttcttcc
      661 tgatccaata atttctatct cttcatttgt catctgatgc aatacttttt cgatttttcc
      721 ttgaatggtt ttatcgtcat ctccaagtct ttgccatcct gaatatcttt ttccgtcata
      781 ttcgattgtc aacttgatgt ttctcatatt ttagtggctc ctctgtcttc catttggtct
      841 tctctctacc tttttaagat tgtagcacaa aatatagctc cttgcttctc taagacagaa
      901 gctatacaag aaaactgtgg aaatatatat ttcagaaaaa caaaaaacag ccaccggatg
      961 aagtatccgc tgactgttca atttgacggc tcaagtttta ctgtttgaga tgcaagatac
     1021 tcaaccaggc aatgggcaca taattaaaga aaaaactgat tctttggcaa aaacctattt
     1081 tattcagtaa tggccaagaa tttatagaag gaattcttgc cagtccataa atcgccgcaa
     1141 aaagcaaact gatcacagac agtccaaggt ataagtggct tacgtccatt tgcccatttt
     1201 ttcgatagat caagaaaaga agaactggaa acaataaaaa accactgtaa cctaaacctg
     1261 atccgatatt atggacccat gtcgagacat tccacgaaga ttcatgggta ttgatactga
     1321 acaaacctgt aaagatacaa tcacctatac catagaacgc gatggctgct gtaactaggg
     1381 tagctaacac acgagatgta ctaacaaatg cagcatacaa tgcaggcaat gacaggatga
     1441 aaaagatccc tgaaaccaca gaccaaataa gaaacgcttt tcttacagga ctggaaacct
     1501 ctccaaatac actgatcacg ctcttcattt gatctaattc aggataatac aatcctaata
     1561 cgtacggagt caaaaaatca ctcagcacgc ctaataataa aaagaaaaaa ccaaatttac
     1621 gtaaaaaatc catgatacgc ctccaataac aattacctat gcttttaatt gttattataa
     1681 acgactttat cttgatttaa cagaaacctc tatttacacg aacatctata taactcatta
     1741 aaaactcgaa tcattttaaa aatactaaat atctaacgtt caacgttcac ttaatccatc
     1801 taaacaatct ttcaatttga ttttttcccc acttctttta cgcgcgccta gctctcctat
     1861 tgcagtaaac aacagatcac ttgacgaatt taaggcagtt tccattgaat cctggataac
     1921 accgataata aatccaatac cgacgatttg catcgcgaca tcattagaga taccaaacaa
     1981 actacatgct aatggaatca ataacagtga accgcccgca acacctgaag ctccacaagc
     2041 agctaaagca gacaaaatac ataaaaggac tttcaaaaca aaaggtgctt caatccctaa
     2101 agaatgtaca gcagtcaacg tcatcaagga aatggtaatc gcggcaccgc ccatattgat
     2161 cgtagcacct aacgggatcg atatggaata agactctttt gtcaatttca atctttcagc
     2221 caacatcatg tttatcggga tatttgcggc agaacttcgg gtaaagaaag cgggaagtgc
     2281 gctttctttc aaacaaaaga aaatcaatgg atagggattt tctttaataa acaaaaacgt
     2341 gaggaatggg tacacaacta atgcgacaaa cagcatcgta ccgatcaaaa caagtaaaag
     2401 ctgcagatac tctgccaatc cagcgattcc agtcgtagca attgattgat aaaccaatcc
     2461 taaaatccct atcggagcaa atgcaataat cacttgtacg acttgtgaca acgctataga
     2521 tatctgatcc accaactctt ttgtcgattc tgaacgtgct cgaaaagcta gtcccaacaa
     2581 tacagcccag aataagacgc caaggtaatt cgcatcaata agagattgaa caggattttg
     2641 tgtgacattc gtcaacatag tagataaaac actttccaaa ctttgcggtg ctttttcaga
     2701 tactgtttct tgtaaagtaa taggaacagt aaaaattgaa cttacaataa ctgctacaag
     2761 tgcagaaagc aatgttccca ctaaatataa gatcaaaata ggcttcacga atgtcttatt
     2821 cccaatttta tgcttggcaa ttgacgccat cgtcaagaaa aaaaccagaa taggtgcgat
     2881 tgccttcaag caactgacaa acaacgttcc caatattgaa ataaatgtcc atgtggggaa
     2941 aaagatacca aacaatattc cgactaaaat accaacaaca atacgttgaa ctaacgacat
     3001 atccaaaaac ttctctaaca aatgaccacc ctttcacaat tttaacaatc attgtatcat
     3061 tttatgcaaa gaaactaaag gtataatttt ctaaaaattc taacaataca aacaaccatt
     3121 tcttgctaat tttgtacttt ttctgtctac acgttgtttt ttgagatatt ctaagttagg
     3181 atgttattaa tgggcaactt atcaggaaac gttttcttat gtttttgtcc aatttttttg
     3241 tgaggtgttt attcttgaaa aaaataaaga aggagagtta tggcttcctg acaatctttg
     3301 tcgcttgtat aatgatggtt ttacagcgta tattgatttc agcagtcact attcctacat
     3361 atgcaacaaa ccctggtcga ttctacatct atacattttt acaaacttcc gttgttattg
     3421 gtgcaaattt gatcccactt tacatgggtt accaatatca aaaaatcgcc cgtttaaaag
     3481 ttttacatta tttaagtcgt tttgccttta tattcctaat agccacacta gtttgcaata
     3541 tcttttttta cgtacaagct ggcagcttga atattcgtga ttattggctt atcctaacac
     3601 ctatcagtca gaattacttt acttatgctg tttcttgtac tttgcttttt tgtagtattc
     3661 cttatacagt tggattttta aataaattat cgaaaacaac aattaaatat ctactattat
     3721 ttttaacaat tggattagtt ggctgctcta ctctatttaa taaagacccg tttgcattac
     3781 agaatggaca gagtatttta tggatttttt atttattttt aatgggttat ggtttgaaag
     3841 aatggaactg gaaagaaaag gtccgctata agcttcctca agtatttatc agcttgattg
     3901 ttttattcgg tttgattatt ttgatgacac aaatttcact catcatcaga ggaaatacag
     3961 atacagcgct gaggttttct aaaccatatt ctctcttcgc aatgtattat actttctctt
     4021 cgtttttatt tttagaaatg ctatctgata aattaggtat aaaaggaaga ggaaattttc
     4081 ttgctgtatt tttgattgtc actcaagtta tatgtaattt ccctttagtt tcttatcgcg
     4141 tatctacatt tatgaaacgt gaatttccaa actcagggaa ggcatggctg ataaatatcg
     4201 ggcagttttt tatttgatat ttattagcag tgtccctcct agttatcttt ttattttata
     4261 tacaaaaaat ccgtttcatt catcgtttca tcgaatactt cgcttttgat tcgattgaac
     4321 aattaactca gcgttggaaa aaaagaattc attggctttt tgttcataaa agttattttt
     4381 tagttgcagc atttttttac tgctttacct tcgtgcagat tttcgtttta gaaccaaaag
     4441 aaggttggaa agaaactatc caggttgcct taaaaatatt tactcagcga caagcaccca
     4501 tgatcctgac aatcatcatt attatgggat ttttcttctt actattgttg atttccaatc
     4561 gtttttggta cgccttgact gctaccttga tcattaactt actgctcact atttcgacag
     4621 taatcaaaat ggaaatgcgg gaagagcctg tctttccttc agatttaaaa atgctgaccg
     4681 gattgtcaga actattatcg atggttagcc cagtcttatt aatcgtgggc ggattgatcc
     4741 ttctcctatt attgattact agtattattg tacaacgtag actacaaaaa cagtattcct
     4801 tgaagattca ttggaaacgt cgatttatca gtatcgctgt attattagga tgtttttcgg
     4861 gtgtcttttt cattaatcac aaaaattcgc cttctttctt gctgtttaat ttatttaaag
     4921 taaacaagac tttctttaac cagcaaggcg ccgtaaaaga taacggacca gtcattcaat
     4981 tcctaaacaa tatcgacatt aaaatcatgg aagaacctgc tggctattcg aaagaaaaaa
     5041 ttaatggaat aatgaaaaag tacaacacaa aggcagatga aatcaaccaa acaagaagtg
     5101 actggttaaa caatcagacg atcgttctca atttaagtga aagcttcagt gatcctgcac
     5161 gtgtccctaa tctgacagta cctacagacc ctattcctta catcaaaagc attataacag
     5221 aaggaacagg aggattgatg ttatccgtcg gttatggtgg cggaacagct aacatggaat
     5281 gggaaggact gacaggcttg agtatcagta acctgtctgc ttcgttagtt acaccttata
     5341 cccagctagt ggagcgtcag aaaataagtc caaatattac cgatctattc gatgaaaaaa
     5401 tagccatcca tccttttaca gctgctcttt atcgcagaaa acaagtgttt gataaatttg
     5461 gttttgacag gttctattat ttagacagtc cggataaatt aacttatacg gataaaatag
     5521 aacaaagccc acgcatatcg gatgattcag catacaaaga aaccttgaaa gctttacaaa
     5581 gcaatacgga aacgtcacaa ttcatccaat tatccactat gcaaaaccat atgccttatg
     5641 atgattacta tagtgaattg aactacactg ctgaaggaac tgctgtcatt cctaatagaa
     5701 gaaaagaatt acaaacttat atgcaaggcc ttcactatac cgatacagca gtaaaaaaat
     5761 tcatccaaga aatcgacaaa atcgataaac cgattacctt tgttttttat ggtgaccatt
     5821 tacccgcaat ctatagtggg aatgattcga aaaaatatgg attagaacag caccagacag
     5881 attatttcat ttataacaac aagtatagtc gtgaacaagc agctacgtta aataaagaag
     5941 ttgttgctcc taataacttt ggtgctatgg ctcttgagca tgcgaatatc aaagtaactc
     6001 cttactatgc gttgttgaca gaagtatcta atcatctacc tgcattaaca attgatccta
     6061 cagaaagctt gtctaatcgt tttaatggaa aacaggtctt tgttacagag gatagtcaaa
     6121 ttatccaaga aaaaaattta actgagaaac aaaaagaaat tctagaagat tatcgtctga
     6181 tacaatatga tcttgttgca ggtaaccagt acagtgcaac atgggcgaca caaaaaataa
     6241 aagactaaca aataaactga gcaaggggtt gtgataaaag acatgtcaca accccttgtt
     6301 tatctcatta atttgcttgt ccataaacga tttgattaaa gccatttttc aattcattat
     6361 tcgctgtctc gttgaagtaa agataattat cgggattccc ctgattttgt tgtgtcacca
     6421 atacttttgg ctgattttgc tgaaacccga atagatagac gtgctttttc agatatggtt
     6481 ctgtctctgc atcggaatag acggctgtga tttgatagtc tgcttgacct gtcccacttt
     6541 ctgaccattc tgcagaaaca ggcactccac caatagccat cttccactcc ccgttcaaaa
     6601 tagcttgagg gactttaaga ccatataagt ccacactcat ttgattcgta taacttttgt
     6661 attgttgtcc cattgtttgg ccccatttgg tcataaatgc ctctaattgt gcggatttgt
     6721 ctgcattcca cagtgtttgt tcaacttgtt cgctgctttc tgaagaggaa gatgaagcct
     6781 ctacagaaga acttgaagta gatgtttgag ttgtttcagt cgttttggaa gactctgacg
     6841 aagtagaggt atctgctgtt tctgtacttg ctgcagttga cttgctctct gtgctagttg
     6901 ttgtagtagt tgcaactgtt gctttcgctg tttcttttgt tgattctttt ttcgattcat
     6961 tcccgttggt acaaccagct aacaaaaaag ctagaccaat tgttactaaa atcctttttt
     7021 tcaattaaaa aactcctttc gattactccc acttctttat tctatcaaat aagcaatgtg
     7081 attttattga tttttcgtat tttctcatca atctttcaaa tcttctaaaa actgagaagc
     7141 acccgctgat gttgtctgta atacatcagc gggtgcttct tttattttaa tcttcgtgat
     7201 tttccaattt acctcacgct ttatatttgt atttgaagaa acatagactt ttagtcatca
     7261 tcgtcttcct catccaaatc ttgtcggaca gtttttcctt ggagtctttg tacttggtag
     7321 atgatttctt tattgaaact taaaagttca acaagcaatt gttgcaagcc atatttttct
     7381 tctttttcag ctaatttgat tgcccgtgtg ataaagacat tttggaaatc aaaatctttt
     7441 gcaaagtttt ccaacattgt tgaggctggt aaatatttgt tttgaccatg ttcgtaaatt
     7501 tttccataac gcatgacttc ttctaaagta gacggaacga tttcattttc aatcactaac
     7561 tcatgagaga ttttattgaa ccatctcgct tcttgatcag catattctga aaaaagggta
     7621 cttaattctt gcgaagatgt acccaaaaca tacaattgtg cttggatcaa tttcatttct
     7681 tctaatttaa aatttgctaa tacatgcccc accatggcgc cagcagttgg tttatgatgg
     7741 tcgatatctg cttgttttgt ttcttgaaca aatttttctt ccactatatt cattgattta
     7801 cgcctctttt acttttgctg attggacttc ataacctaat ttttccacaa ctgcagctaa
     7861 ttgttcaggg tggacttcat ctggatcaaa gtttgctttg attttgctcg cattaaacaa
     7921 aactttcgta ttgcttaccc caggctgttg agaaaccgca tgttcgattt tttgcataca
     7981 gcttggacaa gctagtgtat ctaattgcat aataattttt ttcatcgtag ttcttccttc
     8041 ctttttcttg atagtcttat tctagattac agcttccata aaaaaattga ttcttatcaa
     8101 gttttacgat ttttcttctt tgctttcgtg tccaaaatac aataaacgca tcgcgttaaa
     8161 gataacgatc aagatactag cttcgtgaac gaacatccca ctagccatgt aaataaaccc
     8221 ggcaaataag ccgttgagta aaaataagac gacaccaatg gcaatcacta cattttcacg
     8281 ggtatttaaa acagttttct tagccaagcg gtaggcatga accaacgatt caaaattaga
     8341 ttgcatcaag acaacgtcac tcgtttcgat agcaacatcc gttcctgatc ccatagcaat
     8401 cccgatatca gccgcagcca aagagggaga atcattgatt ccatctccaa taaaagcaac
     8461 gcgcaatcct tgttcttggt attttttcac aaattgaacc ttttcgtctg gtaataattc
     8521 agcatggact tcatcaatgc ctaacatatc agctacataa tcagcagtca tctgattatc
     8581 acctgtcagc atcactaact gttttgctcc tgcttgtttc aacttagcta attgttcagc
     8641 gacttctggt cgaatcacat ctgacacacc tatgatttga gtgatttttt tgtcgattgc
     8701 tacaataatg accgagctgc ctgtttgttg taattgatgt aaatcttgta cttgctttgg
     8761 tgtgagagaa agtttgtgag cggcaatcaa tttggtgttg cccgcacaaa ctgtatgacc
     8821 atcaatctca gctgtgattc cttgtccctt gattgtctga ttatctttga ctgctaattg
     8881 ttgaaaatca atgtctttct cctgagcata atggatcacg gcgcgcccca gaggatgatc
     8941 ggataacgtt tctaatcgag ccactaaagc taagctgtcc ccttcatcct ctgtatagtt
     9001 cttgatagtg gatacagcag tagttccttt ggtcaatgta ccagttttat caaagacaaa
     9061 agtatcgatt ttggaaaaag tatccattgc ttcaccgcct ttgactaaga tgccccgttt
     9121 cgctccatta ccgattcctg ctacattcga aacaggcgca ccaatgacta aagcgccagg
     9181 acaaccaaga accaaaacag tgattgctaa acgaaaatca cgactaatca gaccaacaac
     9241 caacgcaata agtaaaacgg ttggagtata atactgagaa aatcgatcaa tgaatttttc
     9301 cgcatgggat ttggtatctt gtgcttcttc tactaattcg ataattttgg caaaggtcgt
     9361 atcatctccg accttagttg cttcaatcgt cacgtagcca tctgctaaaa tcgttccaga
     9421 gaagacttca tctccactga ttttgacgac ttgtcgtgat tcaccagtca ctgcggcttc
     9481 atccgcatac cctttcccgt caatgactcg tccgtccaca ggaatagctc caccagtttt
     9541 tactaagacg atatcgcctt cttccacgtc atcgatttcc acttcttcag tcgttccatc
     9601 ttcttggaca acactagcag tagatggggc catctcggtc aaagccttga ttgactcccg
     9661 cgttttggtc aatgtttttt gttccagata gctaccaaac aaaaacaaga atgtaacgat
     9721 agctgactcc ttgtattctc cgatcataaa ggcaccaagc acagcaatag taacgagtaa
     9781 atcaattgag ataactttga ctttcactgc ctgatacgca tggatcataa taggtatgac
     9841 cgcaataata gaagctatgg ctagagcaat gttatagaac aagacaaaac cagtaaattt
     9901 tccgataaaa ccaaaaataa tcaacacagc tgataaggcg gtgatatgat ttcgatgctc
     9961 ttggatccac ttttgtaatt tcatctttct ccctcttttc ctttcattct tacgagacta
    10021 agtatagata cttatccatc ataaaaaatt gaccactatc aagtttagtc aaaaaggcgg
    10081 ttttcttttg gtagaataca ctacaaaaaa tagttagcaa gaagactcac taaaagtgat
    10141 cttgccaact attgtcgttt ctatcgaaat tttcattgaa tgattttcct gtacagcata
    10201 catcggagat ctatttcttt atctaagatt tttatcttgc taattttttc ctttagtctt
    10261 tcaaatccac gtcgttcata gaattgatac gtacagccac tatctgtaaa aaggaatatt
    10321 tcttttcctt tctctctttt ttcaaattct gttagcaact tggtaccgat gccttttgtt
    10381 ttcaaatcag gatttgcagc taaaaaaatg atctctccat ctggcgaatg cttctttaaa
    10441 tatgctgcaa gcatttgttc atttgctgtc tcgtaagctc ctttactttc tttagcaaat
    10501 atattttgta aaaaatcgaa tatcttaaca tatatttgct gtccaaaaga acgatgtttc
    10561 tttttttctc cttttatctc cgccagcaaa acacctgcca actcgtcctc tgcatacaaa
    10621 gcaagaattt gagttgctcg attcaactcc atatacaaaa aatatcttcc gtaaagattc
    10681 agcagaagtt cattttccat atatctctca aagttcattc cttcaacagc aaaatagata
    10741 gcttttttgt aatctttctt ttctaagggt ttaaaagtta gtttcatcat ttcgcctcct
    10801 caacttcaat gattgtgtta tacttacatt ataatagaca cagtgtctac tatctataat
    10861 caatcatcta taagtttgtc gattaagcga cagctttgct ttgatatgtc ggataaggag
    10921 ataggtaaat gaaaaagaca gatagacgcg tcaaaaaaac agaaaaagct ttggctgaaa
    10981 cactatccac attattagta aataaaaaga ttcaagcaat cactatacgc gaactaacag
    11041 aaacggcaga tgtacatcgt tcgacttttt atacacatta taaggatatc tatgatctat
    11101 atgatcaatt agaaagcaac ttttttcggg atctaaatga aattctctct tatgatccag
    11161 cccatagcta tgaggaacta tacactcgct tgattgacta tgtttacgca aatacttttt
    11221 tatatcgctt atttatcctc aaccatggtg atatttcgtt tcagaagaaa gttaaacaag
    11281 ttattgaaga aaactatctg aacatatggc tatatgaaga caagaaaacg attatcacag
    11341 aagaaatgag attctttact acgtaccacg tccaaggttg tctatccgtt ctcaatcggt
    11401 gggtagaaag caattacaag tactccaaaa aagaattatt agaactctta cagaaactga
    11461 atgatcacat agagaaaatc atgccttgaa taaaaacata ctaagcttag ttaagaagaa
    11521 ccgtaacctt ctcgtataac aactgaatct tatttagcca aattgtttac tgaagatttt
    11581 ttgagtaaaa tttctataat tcctacttat tgaaaagtag tttgtagtgc tgcttctccc
    11641 tctctaagtg atatatcttg ttgtaccaat caaattcacc tcatcattaa taaattactt
    11701 ttaggctaat ttattacaac ttataggttg aagctgtaac caatttatag tcatattata
    11761 tttttatcat ccagtttatt gaattcttct cgtttacctc aattcatttt caaggggaat
    11821 cagctcatca tctaacattt tacgccatgc tcgcttcatt tcttgtgggt atttaaatgg
    11881 tttcgcttct ggatgtttgg ctttatatcc ttcgtaatcc ttactgttga taattgcttt
    11941 catattagga attggatctt cacctggcat atattgcaga ttagaagcat gtaatttttt
    12001 ctcagaaaca aaccactcat tggaaaagac atgaatcaaa tcatcactta cttgtgtaaa
    12061 atagcgacgt ttaatgacaa agatatcttc attgctatct agtgtacctt catttctttg
    12121 tgcttaaatt caaagataat tttctcaata aagatttttg attccagtaa gattccttta
    12181 ctccttttac aacatagcgt tgtcctttgt tttgaaacat cttcttcccc tctttgccat
    12241 taaaaatagc ccaattctct ataaagaaga ttaagcttca ttattataat ataaagttta
    12301 aatttggttt attacttact ttttcttatt ctctagtaag ctaatattga aaaaaatgta
    12361 atcagatcat tatttttata tgttgtaact tcctgataag aaaactaatt aaaagaaaga
    12421 ggtaactaca taaactaatt aaaaaagcta acttcatagt tggaggataa atggaagaaa
    12481 cttcaatgat tgtttctcct tgtgttcctt caatcgacac tagtcctatt atcaatctct
    12541 cttttttgtc catttacttt tgcgactgtt ccccaataat caaatacagg aagcgttatt
    12601 ttttgtcctt tagattcatg tactgtatag actattttcg aatccatcac ttgataaggc
    12661 atagtatgcc attccttgcc aattcttact tcatgattct gcaaatgttc tttgtattgt
    12721 aatgcttccg tgggtgcata gtcataaagt cctccgggaa ggagtgtcgt gtaacgaata
    12781 agattttctt gattcattac caagtgatct ctctgagtga caactttatg ttcatagttt
    12841 gcttttgttg cagcagatac agccaacagt aataaaacaa ttgccgttat attaactact
    12901 tttctttgct tagctgatgt gctcttcatg aaaacgaacg ataaaatcaa cgagccaaac
    12961 agtacttgaa agcctaagat tcgccaagga aattgaatca tttgaatggg tgtattttgt
    13021 aataaagacc atggaaaaaa tttggtggat aagagccaag agactaccgc actaaggtaa
    13081 atcacttttt ctttgcgatt aaatccttta aaaaagaaga gtggacagat caaagaaata
    13141 ataccaatga ttcctaccgt aaaggttgtc aggtcattat tcatcgcacc aatcaaacta
    13201 tccgagacat ttaatgcttg gtgttgtaag gtcgttttat ctggctcatt aatcgattga
    13261 accatgattt gtcggaacat cggataccaa aagtatgctg ttaaaagaat cgtcattcct
    13321 actgcctttg acaactccac aatcaaccgg atgctttctt tttttcttgt ttcacttact
    13381 acaaagccgc ctaagactag taagccaacg gctattacac tcataaaagt ggaaagaaca
    13441 tgtgtataaa tgagtaagct catactgact gctaatggaa ttgcacatgg ctttttctca
    13501 taaatcagtg cgtaagcata atacataact atcggtataa ccgtaagtgc aatcgcttca
    13561 gcaatagcag aacgatgata aatatcaatc gtacggtacc cataaaatgt atataaacag
    13621 ctaaatataa aagccgcatc gattcttttt aaaaatttta gtccataatg aaacatcagc
    13681 atgatagtac aaacattcaa tagccaaaca tataagatat aactaacgat taaattatta
    13741 cttatccaat aaaaaatgac tgccggaaaa aaggtcaagt agggataaaa ataattcact
    13801 ccgctcccat aatgattaaa cgtcgtaaaa ttgattggac cagaaaaaat tgaagataac
    13861 cctttgactc tagcaaaatg gaaggcaata tcccccgatg tagaaatagt atgaacattt
    13921 ctaaaataat tgattgaata aagtccagca ataattgcta ggagaatgga caatattatt
    13981 tttttcttta cttgcattac ttaattatat actcctttca tggattgctt tatctagtat
    14041 aacttaaatt ttaaataaat cgttatttat ttttactctc acttaaaaaa gcactaaaat
    14101 tataagagag ggaggtaatg gtctgaacac caagaattgt tccaacatcg aattgcttaa
    14161 ctaatgagtt caaagcttaa ttatgtggct cttatattta ccgagcgtgg attgcgatct
    14221 ctttagcgaa acaaacatct ttcataaaaa aaacagccat atccgctttc ttggatatga
    14281 ctatttacta ctactttact atctttcatt cttcttgtct cacttatgat aaggcgctgg
    14341 gtatcatgag tgaatgatat tgctgaatac aaatagtccg accacattaa gttgatcgga
    14401 cttcataagc attttattga ctaatacttt tttgcttaag aattgattct aacatctttt
    14461 gctaaagtta agcatcctat agttcctgca ttatctgcta acttaggtgt gacaatgtat
    14521 tcttcgatat ttggcgtatc gacatagccg ttaattagtt ctaaaaaacg tctttgtact
    14581 ttctttttca gatgttcttg ttgcatgaca ccaccaccaa aaattataat atctggtgaa
    14641 agcatcaggg tcgtattaca ggcacattgt gcaatataat ccgcctcgat ttcccagaac
    14701 ggatcttcta tagaaagatc ttgtcccttg gttcccgtac gcatctcgat agcgggtcca
    14761 gatgccaacc cttcgagaca atcatgatga aaaggacaag taccagagaa agtatctcct
    14821 gaatgtctct taactaacgt atgccccatt tctggatggc taaacccttc aacaaaaatc
    14881 ccatcttgta tagctcctcc accaattcca gttccaacag tgtaataaac aacactggat
    14941 aaaccttttc catgacctga aacatactcc ccgtaacaag cagcattcac atcggttgtc
    15001 caggcaattg gaatttcgaa atgcttattc aacgttccaa caaaatcaaa atttttccag
    15061 gcagtttttg gagtagaggt gatatgtcca taggtctttg attcacgatg gatatcaatc
    15121 ggtccaaatg accctactcc aatgctttct aattgttctt tatagtgatt aaagaaatca
    15181 attaccaaac tcattgtttc attcggtgta gttgtaggaa aactcactct ttctaaaacc
    15241 tttaaatcat cattgccaat ggcacaaaca aatttagtcc cacctgcttc tattgagcca
    15301 tacatttctt actccaccgt ccttttatct aggaattcgt tcttccctgt ctaatagttt
    15361 ttcgaaaaac tcatgtggtt ccttttggta ccaataggca acagaagaaa tatcgtcttg
    15421 acgctcataa agcttgatgt catcatttcc tagggtttgg aaagtaacac gtaaattttc
    15481 tttgaaacta atggggtcgg gtaaatgcca gcggtacaac ccatgcatcg gtaaagcatc
    15541 atcgccaaaa ccatgaactg gatttggatt aggttttcca gcactaaaat aatcccgggt
    15601 gtgatctctt ttagattgaa aaggatagcc cataaatagc gtattaaaat tttgagcata
    15661 tgccctttct ccaaagttct ttttatggaa agcccaagcg ccgccaaaat aatcttctgc
    15721 tcctgtagat gttattgtag ggaaatcttc atctccatct atataaaact taaattctcc
    15781 ttccccccac cagtatcttt ccaatgcgca caaagcaaag taggttccta cataataccc
    15841 agtgcctttg attccatcaa taagggtgta atcttttcct tttgtcgtga tgggttcacg
    15901 gttccattta gcatgaaaat acatcgcatc atccggtact tcagtcaatg cataattaaa
    15961 tgtataaaaa atgtgcttaa taaactcagg atgttcattc gttaaagtaa tcttagcttt
    16021 ttttcgaaat ggcatctcaa aatagcaatt catccctgat gttggattca ctacgattgg
    16081 taaggaattc acttcgcatc ttgtcccaaa cccattacaa aaaaaatctc ctaatggact
    16141 ttctacagaa ggagtggatt catcatccca ataaatacgc aaaattaaat cacgtaagac
    16201 gaaactccca gcgattgttt tgtctgtcac tgtcatccaa aaatgacgta aaattccagg
    16261 gccttccatt tctgctaaag taattgtctc tccagcattt atcggaacag aaggtgaccc
    16321 ttttctccca attcctagat gactcgctgt cattgccgct ttcccttttt caccattttt
    16381 attttctggt gaaatagttc tactttcctc tcccttgtgg agccatatat tatttaaaca
    16441 attcatttta ttcgtcctct atcctttctt cacttttttg attattcata tagatgattt
    16501 gttgttgtgc ctccgcaata attgctccaa tatctaaatt atcatttcct aactgcaaag
    16561 cgattgacat tgccaaggga agattcattc ctgcaattac gtgcactctg tcagaaatat
    16621 aggtaaaaaa cttttgattt acacttcctc cagccatgtc agttaaaaca attatttcgt
    16681 ctgtagtatc cactaactct ttaatttgtt catctatatc atcaatttct tcgacatatg
    16741 cacataagct actaatttga ttatgcatac ctgttaaaaa ctctagtgtc tctttaaaac
    16801 cctcagctag tattgaatgg ctagcaatga tcaatcttct cataattcaa atccttttcc
    16861 tttacgctaa tattccaaat gcagccataa ccatcgcaaa aacaataacg agtagaatca
    16921 aaatggtcat actgattttt ttcttactga gtagataata tgctgcagca gtaataatta
    16981 ctggaattaa tgttggtaaa attttgtcca acattggttg gattttcata ctaacttcac
    17041 caaaagtgaa tttaagtggc gttgaaacac tgataactga agcaattaat gatccaacta
    17101 ctgttagccc caatactgaa gcagcttcag ttaaataatt aatcttttca ccgtattcag
    17161 taacaatctt cattccctgc ttataaccaa attcaaagcc tctcattcgg aaaaagaaga
    17221 ttaccatgat taaaatgaac cataaaaaga ttcctacagg attattttct aaagccatat
    17281 aagccgcaat tgatcccatg atggttggga tcatcgtcat caaaagagag tccccaatac
    17341 cagcaattgg acccatcgta ccaactttaa agtcattaat cgcatctttt gcttctaatc
    17401 cttgcttttc ctccattgca acacaagcac ctaaaataat ggctgccagc caaggctgtg
    17461 tattgtaata ctgaaagtga ttatttaaag cttcgatgta ttcatcatca tctttgtata
    17521 attttcttaa aataggtgac aatgcgtaag tcacagatgc accttgctgt gtttgataat
    17581 taaaggtaca aactgacatc aaccaacgat agttcgcttt cctaagatcc tttttcgtta
    17641 cttgatattt ttcgctcatt ttattcatcc tccccaataa acccaacatc agaagctccc
    17701 gcagaagcag tgatttgtgc atctttttca gctctatgat acacattaaa tgctaaagcg
    17761 aatcctatga tcgccgctcc aataataggt accttcaaaa aagcggctaa gaaaaatcca
    17821 acaagtaaat aactaatgta tcgacctgta ggcataaagc gtaacaacat cgcaatacca
    17881 acagcaggca acatttttcc ggctaatgtt agcccatcca taaaccaatt aggtaaaaca
    17941 tccaaaacgt aattaacagc agactgtcct aaagtaacgg caataaatac tggaattgct
    18001 gcagataaac caaagaaaat tggccccaac cacaaaacac tattcatttt cttaaattct
    18061 cgtttattcg catattcctg tgatttgcga acaacaaaac catttaagat tttgacaatt
    18121 acatctagtt gcacccctaa catacctaca ggtagtccta ttgctaatcc ggcttctact
    18181 ccaagctggc taccaaatgc cgttgcaata attgcgcacg ttccatagtc cggtacagat
    18241 gagccaccaa aaccggcaac tcctaatgac atcaattgaa ctgtaccgcc aactatcaaa
    18301 cctgttttta tatcacccat caaaattcct gtgaataatc cccaaaaaac tgcgtaattt
    18361 acaaagatca tcggaatccc ataataatca acatgtttaa taaatgctaa tatagtcagc
    18421 ataataattt gaaaaatagt aaaatgcatt atccttactc ctttatccta attttgattg
    18481 aatttcctgt gccttatccg ccggaacaaa ttgtgtaaca atttctacac cagaatccaa
    18541 caatttttta tacgtgctga tattttcatc tgatgcatag gctctagaag atagctgtaa
    18601 tgcattatct ttaacaacag taccgccaac aattagtcgg tcaattctaa taccgttatc
    18661 tactaaatga aggattgttt ccggctcttt cacgatgaca aatacttttt cctgatcgta
    18721 tttccccttt ttaaaattcg caatcgctgt ttcttcagtg ataattgata cagccattcc
    18781 agcaggtcta gctaaacgca tacttgattt ttggatgtcg ttatttgcga cagaatcatc
    18841 gatcaccatc actctgtttg ctttagacat tggtgcccat tgcgtgacaa taatcccatg
    18901 caataaacgg ttatcaactc tcgacataac aatactcata aatacttcct cctttatctt
    18961 tcattttctt acaagcaatt accatgccaa aacaaaaaga acttgataaa tcaagctctt
    19021 tttacataat cataaacgta tttaacctca tgaatcggga tgtcgacact ataataatgt
    19081 tcaacgacac tgaaagattg cttaaaatgt gtctgaaatt tttgaaattc ctcactcgtt
    19141 tcattgaaat aaatttcatc ttccaaagta ttttgtttta ctaatcgttc aattaagcaa
    19201 ctaatgtgaa catataatcc gaaacacgta ttattatcaa atgaaattcc tagatcattt
    19261 tgtaagatgt atatagcatc tgaaacccgt tctaataatt tagtcggatt taatatggtc
    19321 aattgctcca ttaaattcgt tagactaaaa ttcttcagaa tattattgtt caaaactttc
    19381 agttcattat cattaaagtg tctattcaat tgattggaga atttacttat attcattcct
    19441 aaaatcatat ctt
//
LOCUS       DADVXK010000047        19445 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.047, whole genome shotgun sequence.
ACCESSION   DADVXK010000047 DADVXK010000000
VERSION     DADVXK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.047"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..593
                     /locus_tag="KB909_001575"
     CDS             <1..593
                     /locus_tag="KB909_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6837599.1"
                     /translation="TSTLEEALKILETSGYRCVPILDSSGNIFRGNIYKMHIYRHKAN
                     GGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAVLDSENHFYGILTHSTLLN
                     MLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIASCITLDIEKDEYIRRTLI
                     TLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(649..1152)
                     /locus_tag="KB909_001576"
     CDS             complement(649..1152)
                     /locus_tag="KB909_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6837600.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(1165..1211)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1749..2714
                     /locus_tag="KB909_001577"
     CDS             1749..2714
                     /locus_tag="KB909_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6837601.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(2813..3985)
                     /locus_tag="KB909_001578"
     CDS             complement(2813..3985)
                     /locus_tag="KB909_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837602.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(3972..5117)
                     /locus_tag="KB909_001579"
     CDS             complement(3972..5117)
                     /locus_tag="KB909_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837603.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(5131..6063)
                     /locus_tag="KB909_001580"
     CDS             complement(5131..6063)
                     /locus_tag="KB909_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837604.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            6180..7259
                     /locus_tag="KB909_001581"
     CDS             6180..7259
                     /locus_tag="KB909_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6837605.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            7256..7874
                     /locus_tag="KB909_001582"
                     /pseudo
     CDS             7256..7874
                     /locus_tag="KB909_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(7984..8211)
                     /locus_tag="KB909_001583"
     CDS             complement(7984..8211)
                     /locus_tag="KB909_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6837606.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(8314..10902)
                     /locus_tag="KB909_001584"
     CDS             complement(8314..10902)
                     /locus_tag="KB909_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBB6837607.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(10922..11581)
                     /locus_tag="KB909_001585"
     CDS             complement(10922..11581)
                     /locus_tag="KB909_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6837608.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(11630..12133)
                     /gene="trmL"
                     /locus_tag="KB909_001586"
     CDS             complement(11630..12133)
                     /gene="trmL"
                     /locus_tag="KB909_001586"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBB6837609.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(12354..13220)
                     /locus_tag="KB909_001587"
     CDS             complement(12354..13220)
                     /locus_tag="KB909_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6837610.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            13329..13970
                     /locus_tag="KB909_001588"
     CDS             13329..13970
                     /locus_tag="KB909_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBB6837611.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(14032..15393)
                     /gene="mgtE"
                     /locus_tag="KB909_001589"
     CDS             complement(14032..15393)
                     /gene="mgtE"
                     /locus_tag="KB909_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBB6837612.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(15411..16310)
                     /locus_tag="KB909_001590"
     CDS             complement(15411..16310)
                     /locus_tag="KB909_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6837613.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(16312..17109)
                     /locus_tag="KB909_001591"
     CDS             complement(16312..17109)
                     /locus_tag="KB909_001591"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBB6837614.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(17087..17791)
                     /locus_tag="KB909_001592"
     CDS             complement(17087..17791)
                     /locus_tag="KB909_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBB6837615.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            17922..18497
                     /locus_tag="KB909_001593"
     CDS             17922..18497
                     /locus_tag="KB909_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBB6837616.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            18615..19292
                     /locus_tag="KB909_001594"
     CDS             18615..19292
                     /locus_tag="KB909_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6837617.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         5832 a         4120 c         3467 g         6026 t
ORIGIN      
        1 agactagtac attagaagaa gcattaaaaa ttttagaaac ttccggatac cgttgtgtgc
       61 cgatcttaga ttcttcaggt aatattttcc gtggaaacat ttacaaaatg catatctatc
      121 gtcataaagc aaatggcggt gatatgacgc ttcctgtcac tcatcttttg aaaaacgcta
      181 caaagttcat ttacctggat acttctttct tcaaagtatt ctttacgatc aaagagcttc
      241 cttatattgc tgtccttgac agtgaaaatc atttttatgg tattttgaca catagtacgt
      301 tgcttaatat gctctctcaa tcttggagcg tagaacaagg aagctatgta ctgacaattg
      361 cttccacagg aaagcaagga gatttggctg ctattgcaaa aatcatttca aaacacagca
      421 gcattgccag ctgtattact cttgatatcg aaaaagacga atacattcga cgtacattga
      481 tcacgctacc ggctaacact gaagcgaaag tatgtgaaac gatcgtcaac cacttagaga
      541 aaaagaatta taaagtggta gaaattgaaa atttgcaaaa ccaagaagca taatcaaaaa
      601 gcgaaaaaag aaaacagcta atctgctttc ttttttcgct ttttataatt agacacgctt
      661 ttcaaaatca agcgcgcgat ctaaataata catcaatggt gctgaaacag ccatgacgat
      721 aaactcactt aatgcaagcg tgccataggt tgtccaaaat gcttggccac ctgttggaac
      781 taacatataa gcaatcagtc ccatgctgat ggtaaagaag atcgtgttca atactaaacg
      841 catctttaca tttttcactt tgttttgcaa taaagctgtc aggcctaaag aaagcaatgt
      901 ttggccgcca ccaaaaacca catccatgat accaaaacca aagaaggcat tatagacgat
      961 gaccccgcct aaaactcccc aaagcaattt acggttaaag acaactaaat gattcaaact
     1021 ttctgaaata cgaaactgga tcggccctga ggatacaggc gcaactaaaa tagttaacgc
     1081 tagataaaga gccatgatga tgccatttac aacgattacg gataaccgtt gtctgctttt
     1141 cgttttttgc attttctctc ctcttttctc ctagtttttt taacgcggga tggttgatga
     1201 accgcggtta tgtgaaacaa acaataatta taacagactt ttcatttatt tcaatccgtc
     1261 ttatctgctt ttaaaaaagc aaaagcttaa acaatgtaaa cgtttgctaa aaatcgtggg
     1321 atatggtata aagtaagtgt aaggggtcat aagaattccc agtaaagcag acgaagtagg
     1381 atctgcaaga acagaattgt tgtgaaactt aaataaataa aaaaggatgt gggaatttga
     1441 gcaacctctt actagagaac ggtctagcaa gcagctgaag atctaagtgg acatgccgaa
     1501 ccttggaact tctccttacg taagtaatgg atcatgcgct tgctaggctt ttttgtgttt
     1561 ttcggtcttc ggaccttttt cattttccta gacttctgct ataataacca agaattaatt
     1621 ttgtaacaga tttttttgaa aaaacaagtt tctttcattc aaaaaataga aaaagcttgc
     1681 taattattgg ttaaccagca aacaggagta ttaaaatatc ttgttttatt gaatagcagg
     1741 aggaaatcat gaaattccat tatcatatat tgatcaatcc atcggcaggc agcggaaatg
     1801 gctataaagt agcagaaaga attttaccgg tattaaaaaa taagcatatt gactatacac
     1861 ttcattatag tgaatacaaa ggacacgatg ctgagattgc tgaaactttg gcaaaagaaa
     1921 cattgattcc ttggatagaa gaagaacaga aaacaatcga tactttcccc cttttgatca
     1981 tcgtaggagg tgacggcacc ttacatcagg tacttgatac tttctatcag atggaagtag
     2041 aattcccagt tgcttatatt ccagcaggtt ctggaaatga ttttgctcga ggggcaggcc
     2101 ttccaaaaaa tcccaaaaaa ggacttcagc tgattttagc agctcaatca ccagaaaaag
     2161 tccacataat ggcttatgaa gaaaaaataa gtgaaaaaaa aggaatagct gttaataatt
     2221 tcggtatagg attagatgca gctatcgtcc atgcgacaaa tcattcttcc acaaaaaagc
     2281 gattgaacaa atacaactta ggatcatttt cgtatttatt ctctattctc cgtgctttat
     2341 tcactcaaaa aggatttcca attctggtag atgcaggagg aaaacaatta agtttttcaa
     2401 acgcattttt atgtacagca acgaagcatc ctttttttgg cggaggaatc gcgattgttc
     2461 caactgctga tgcgtctaaa ccagtcattg attttgtcgt ggtcgaacga atcaatttct
     2521 ttaaaatctt gtggctcatt cttttactta tacagaaaaa acaattgaaa tcgaaatatt
     2581 tccatcacta cacaacaaac agattacgta tcgtttcaac aacaccgcaa catggtcaag
     2641 aagatggaga agaaatggaa aaacgacctt ttgatatcac aataaccaca actaaacagt
     2701 tgttttggtg ttaataaaag aggttttgtc agaagctaca tctggaacac cgtttattcg
     2761 gaaaaaagga ctgtgacacg acttttgtca cagtcctttt tttactatgc agttaattct
     2821 ttgcccaatt gggttgccat cgatagtttc tttctttacc caaaataaat tggatcattg
     2881 aaaacaccgc agcaaaagca actaagacac aaccattgaa ccaaaaagat tctgcaaatg
     2941 tttgattgta actgagtgtt tcactgatca agttattatt ttgaacaaac caatatgttg
     3001 gtgtgaatgc cgctattttg ctaaccattt ctggcaagta ttctgctggt acaaacaccc
     3061 caccgataaa gcaactgcct gtgataaaaa tatctttgat cccaccgctg gtttctgagt
     3121 tttttaccaa tgaagtgata caagccgaaa agctaatgat cggcaataaa aacaagaaag
     3181 tatttaaaat atgataccat accgttatat cccacgaggt gtggatcact aacagaacca
     3241 ttagaagtaa gaagccactg aacaacagca gcgagtaact aatcaaacta aaggttactt
     3301 tgcgattcaa gtttcgtttg gtaatgggcg cactctggtt tcgtttactg atctctttgc
     3361 gattaaacgc tagattgatg acgctgaaac cgctaaaaat ggatagaaac aacccataag
     3421 acaagaaatt aaaggttgtg cccgtcaaca gctttttcat ccgctgacta tatcccgcac
     3481 ttagctcaac ttctccagta accgagagtg ccatttgtgt ctgttccata gctgcatcga
     3541 ttgttttatc ttcttcttga aacagaatca gtgtttgcaa aaaggtgttc acttgctgtg
     3601 taacaactgt tttagaaaag gcatctgggc gactctgtat cttgatcgtc gccatctttc
     3661 ctacttcgac ttgttcggta aagtctgcag gcagatgtaa gataatgttt acacgattaa
     3721 aataaagagc atcatcgatt tctttttgtg aggttccatc caatgtaacg actgtttcct
     3781 tgtcattcaa atatttacga aggccatcga ctacaggcga ctcttcttca ctaatcaagg
     3841 cgattttcgc atcttgcaga gaggtatttt caacatcaat attttgcgca aaaaagaatg
     3901 tggcaacaac agtgataatt acacctatca gtaaattcga tttatttgct ttaagcaatg
     3961 tccaaatcgt tttataaagc gtcataacgc acccctcttt ccatccaagc atttcctaac
     4021 gcaaaaagga aaataaatcc gatcaaccat agaagattgg tataaaaact agccaaatca
     4081 gtgtagaaat aaagtttata caaactttcg ctgatcaagt tgacgagatt taattgacca
     4141 acaatcggaa tatgaagatc aatccaatac ttcacttgtt ccgaccccat cataccagca
     4201 aaaaagctca tcgcaatcgt cactgaaatc aagatgctat ccttttgcac cagattcatt
     4261 tttggtatca aattaccaac caatgtacct aacaaaatcg cacacaacga ccccagagcg
     4321 gtaacaatca tcaaccattg ccaacgttca ccaaagtcta cttgatagat aaaacgaaag
     4381 acagctaaca taatataaat ctctgtcaaa acaatcgtaa agcttgctgc caaattagcg
     4441 attgaaacta acgattgctt tctaggaatc aaggacaagc gaataccatt tgacgattga
     4501 tttgcttgct gatcctgtac attgcggacc ccccacatcg tcccgtagag aatcgccatt
     4561 ccaatcagag tgaagaaata aaaacttttg aaactcatat tacgacctgc atgaacttct
     4621 tgaaaagata cttcttgttc aaaaacagtc atgatgggcg cgagatcaac gttctccact
     4681 tctgccactt tactcgaaat tataccaata cgctgtaaaa attgatccat gacgtttttc
     4741 atcaacgtct gactcattcc tgcttgaccc acatggagcg aaacagatga accatcaatg
     4801 agataaaaac cagccaaatc atctgcattt agcttttcat tcgcttctac ttccgatagt
     4861 tcctgtactt caaataatgg tttatcattg acttcgactt gttctaagac tgtggtaaaa
     4921 ttttccgaaa gcgctgtttg atccgctttg attacaattc cagtattaat cgtttcaaga
     4981 ttgccacctt gatcaatctc gccaaaggcc gccataaaca tcaatcctaa aagaattgga
     5041 aaggccaatg tccaaaacaa catggattta tttcgcagca gtatttttgt gcgatattta
     5101 taaaaatgcc aaaacattat ttcccctcct ctagtctctc aaatccttgc cagtaatctc
     5161 taaaaagaca tcattcaagg acgcttcttt ggttgctatt tttccgtaac tgatcttttc
     5221 ttcttgtaag attgtaagaa tcggcaacaa tactgtattt agttcagtag ttgttacttg
     5281 gagctgacct tttttataag cgattccatc agaagctatt gttcgctgaa tcgctgacaa
     5341 cacattttct gggagtaatg ggatgtcgat cgtcaaacga tccgccgtcc gtaccatatc
     5401 ttttagagat tctttggttc ctttagcaat cacctgtcct tgatccatga tcacgatctg
     5461 gtcgcaaaga atttctactt cttccatgta atgtgttgta tagacaatgg ttgctccttg
     5521 tcgattcagc tccttgatac tttctaaaat tttattccga ctttgggggt ctacagctac
     5581 tgtcggctca tctaaaaaaa ttaaccgcgg cttgtgggca atcccacatg cgatgttcaa
     5641 ccgacgtttc aagccaccac taagttctcc tggacgaaac gaaacatatt tttctaatcc
     5701 cactaattga atcacctctt caatcaaggc tttccttttc tctttttcgg aaacatataa
     5761 accgcaaaaa taatcgatat tttcttgcac acttagttcg tcaaagaccg caacgtcttg
     5821 aggaacgacc ccaatcattg ccttgacagc ataattttca ggagtcattg ttgtcccgaa
     5881 caatttaatg gttcctttgt cataatttaa caaagaaagc atacagttga tggcagtcga
     5941 tttcccactg ccgtttggac ctaacagacc taagacttct ccttcttgta cttgcagatc
     6001 aaaatgattc aatgctacaa aatctccata gcgtttgact aatttatcaa tttcgataat
     6061 catcatgaaa aactccttcc aaatttcttg ttgatctgac tataataaag tgcaagaaaa
     6121 gaaactagtg acgattggct aaaccacaca tgacatttgt cacaatgaag gagtctgcta
     6181 tgcataaatc tcggctactc aacgaaacta gctttctact ggttatctca ttgcttttgc
     6241 tggtaagtca aggattcgtt gctatgcaag ttatctattt attgatcgcc gttttattca
     6301 ctggtgtcag ttatttactg cctacaaagc caaattggat tttccaagtt attctatttc
     6361 ttttatgtgc ctttttacct gatcttgtcc tgtttctgcc agcgacgatg cgagtgatcg
     6421 cccctgaaga aagccacctt gattacttgt ttttgttagg ttttttgttg atttcgacgg
     6481 ttggtaatca tccccccatc aaggtcgcct ttgtcgtaat tttgctgttt ttttcctttt
     6541 acttacgaaa aaaagatcaa cgaacgaccg atcttgagaa aaagtacatt gtctccaaag
     6601 atactcattg ggaaaaacaa caagagttat cggaacaaaa taaagcattg gccctgtcac
     6661 aagaaacaca attagccttg caaattgtgg aagaacggaa ccgaattgcc cgagacatcc
     6721 atgacaatgt cggtcatctg ctgtcaagtg cgattttaca aattggtgcg cttgaaatga
     6781 tcaatcaaga accaaaacta aaagaaccat tagaaaattt aagtgccacc gttcacactg
     6841 ggatggatcg gattcgtcaa agtgtccatg acctccatga gacatcgatc tcttttcaac
     6901 actccttaga gtttctgatc gctgattttc cttcttctgt tacgattgaa ggaaacttgt
     6961 ttgaaggatt gaatgaaacg cagcaaaact gcttcttaat ggtcatcaaa gaagccttaa
     7021 ccaacagtat caaacatagt catgccaaaa ccgttgtttt acattttcga acgttgccgg
     7081 ccttttatcg cttgcaaatc acgaatgatg gcaccagccc acaaaaaaat tctgctcccg
     7141 gtattggttt gaaaacgatg cgtcaacgtg ttcaagaaca aaagggacaa gtccatattt
     7201 tccaagaaaa ccagcaattt cagttaacga tcattttacc aagggaggga caccaatgat
     7261 aacagtagtc attattgatg atgatccatt tgtgacgaaa tcgttacaaa ccattttaga
     7321 aagcacgaaa gagatccgtg tgttaggcat tggtcattgt gccaaggatg cgcgaaaccc
     7381 atcgtcccga tgttttgctg acggacatcc gcatgcctaa acaaacgggc atcgatgctg
     7441 ccaaagaaat tttggctaaa tttcccaaag ccatcctttt gcttttgacg acattcaaag
     7501 atgaagaata catccgcgaa gcattttcca tcggtgtcaa agggtattta atcaaacaga
     7561 acttgcaagc gattattcct tctgtcaaat ccgcttataa tggacaggcc gtatttggta
     7621 atgaaatcat cgagactttc actcaaatga tgaagaataa accgacgatt gatagtcatg
     7681 cttatgcttc ttttagtgaa cgtgagcttg caatcatcaa agaagtagct gccgggaaaa
     7741 acaataaaga aattgcagat gccttgtact tgagtgacgg cactgttcgc aattacatca
     7801 gccaattact agaaaagcta gatttacggg atcgcacgca attggctatc tatttttatc
     7861 agcatttgca ataagtctta tctaacacaa aaaaacctga atgatgctcc ttcgcatcat
     7921 tcaggttttt ttcacatctt ctattcaatt gtcccgcaaa ccatttcctc acgattgaaa
     7981 gaatcaagga ttcgcagggc tgccaggatt cgttggattg ttcggcgtgt taggcggaaa
     8041 aataggcgcc ttgtctaacg ttttttctag ttttgattct tcacgatcgt ctcgttctac
     8101 atcaggactt tcattcaatt tgaattcttt ttccatctca tctaactttt taaagtcatt
     8161 gccagattct tttgctaatt tcgctaattt atcttcggtt tctttagcca taaagtaacg
     8221 cccccctttt gatttcagct tagcatatca cactgaaaaa acaaaagaaa acgctaacca
     8281 acgatcattt ttagctattt ctcatcttta aaatcaagca ttttttgccg gtataaaatc
     8341 gtagggagaa ctgttttcca taccaatcat cggatctact aactggttat cgatcacttc
     8401 tgctgtaaga acgaaatctt tagaaacagc aggttctacc tcttctttct tttcttctcc
     8461 aacaaatgaa gaaaacagat ctggttccac tgtttccatt acttggtttt tcgtttcatt
     8521 cgtcccactg tcatcttcta caggtagctt ttcttttaca acccgtggct cttttgtata
     8581 gttcccatct tcaaatggat catttccgac caaagaatct tcataagctg ctagtttggt
     8641 ccggagagtg atattcattt tatcattatc catgatcctt gatttcaacg tagtcatccg
     8701 gcttgctgat tcattcgcta cacaagtgac ataggcttgc tcttccccta acaaaatcaa
     8761 cagttcctta ctgcgagtca ctgccgtgta gagcaaatta cgctgaagca tccgctgata
     8821 ttgatggacc atgggcaaaa taaccatctt gaattcactg ccttgtgatt tatggattga
     8881 gcaacaataa gaaagagtga ttttattcca ttcgtttctt ttataagtga cctcatttgc
     8941 atcaaactgg ataactaatt catccacttt atcttcagaa tcttttgcca agatgatacc
     9001 cgtgatttct cccatatctc cattgaatac attcaattcg ggagtattga ctaattggag
     9061 gactttgtct cctatccgat aaacggtgtc gttccaatgt acttcctttt ttccaggttt
     9121 ccctggattg aatatctcct gcatcatttt atttaacgca tcgatccctg caggtccccg
     9181 atacattggt gctaatactt ggatatcttg tgcacggaat cccttatttt tcgctttttc
     9241 cacaatttta gagatcaagg gttcaatttg ataagcatca cttcggaaat aggaacgatc
     9301 tttttgattc tttgtgaaat cttttggcag acgtccttct ttgatctcat gggcaagagg
     9361 aataatacta gaaccatcac cttgccgata aatctgattg agttccattt tgggaatttg
     9421 ttcgatttcc aaaagatcat ggagtacttg accaggaccg acagagggaa gctgatcttt
     9481 gtctcctact aagataactt gcatattcgt cggaatcgct ttgaataatg tgttagccag
     9541 ccatgtatcg accatagaca tctcatcaac aatcaaaagt ccgccttcta attctttcgt
     9601 actgactgaa ggtgtttttt cccgtccatt cagccccaga agacgatgga tcgtactggc
     9661 aggcagacct gtcgtttcgt tcattcgttt agctgctcgg ccagttggtg ctgcaagtag
     9721 aataggaaaa atttcttggg tatattttga aggatccaat tccagtccgt tcaactctgc
     9781 aaaaagattg acgattccgt tgatcacagt agttttcccc gtacctggtc ctcctgttaa
     9841 aataaataga ggggaacgga ttgcttcagc gatagcttgt tcttgcgaag gtccatactg
     9901 tatgccgaat attttttcga tacgccgaat attcttctgc acttcttttt caggataatg
     9961 gatttctttt ttacgactga gaaggcgctg gatcgaatta ccgatccccc attcagaaaa
    10021 gtacaaactg ttttcgtaaa gattagtctc ttcttgttgt atctttcctt cttcaacaag
    10081 ttggataatt acagtagcaa cctgatcagg ctggatttca attgggcgac ttgtttctaa
    10141 aatacggatc gtttgctgaa gcaatgtctc cgccggtacg tatgtatctc ctgtttgaac
    10201 tgcatgctga aaaatctgat gcaagatagc tgctcgaatt cttctcggtg aatctgctgc
    10261 aataccgatt tgttcggcta gattatctgc acgtttgaac ccgattcctt ctatgtcttc
    10321 gactagctgg tacggatttt cttcgatgat atccaaagac tcgttcttat aggcctggta
    10381 gatactgaaa gctaactgac taccgaaccc gtaacgattc agtcccatga tcacttgatc
    10441 catcccgtgg tttagccgaa tcgtctcagc aagcatttct ctttttggct tcgtcaaacc
    10501 ggagatttgt tttaataccg aaggatcagc aatgattttt tcgatagcat cttctcccag
    10561 caattctaca attttttctg ctgttttctt cccgattcct gggaattttt cgctggaaag
    10621 atacgctacg atcccatttg cagttgttgg cttttcttgc tcatatcttt cgagtttaag
    10681 ctgccttccg tatttaggat gatccactaa ttctccataa aaacgataag tctcattttc
    10741 ttgaatatcg ccgaaacttc cggtgactac aatctctttt tcacggtaat cagctgtggt
    10801 ttcactgatg tgtaccaaaa gcactttgta aaaattacta ggattttgaa aaaaaatcgc
    10861 ggcaactgta ccaacgaaat aaggcatttc ttctggctgc atcggaagcc gcctccttct
    10921 tctatagtaa aggttctggt gctgtttcag ttcctaaaaa atctgtttgg ttccatactt
    10981 tcagttcata tggcaataat ctgcaaggct cttcagtctc taaaatcgtc aaactactat
    11041 tgaacaatcc acccatttca cgcaactcac ttagctcttt tcctgtcatc cattgaatgg
    11101 ctgcagttaa agaagctcca tgtcctacga ataaaagtgg gccatcttta tgtcgggcaa
    11161 ccgcatctgc tacaacagtt tcgatacgtg tgattgccga ttcaatcgtt tctccgtgaa
    11221 aaggagaagg atcatacaga tctaaatgat tacgcaaatt cggcagatta tccggatatt
    11281 tctggtacat ttcatcgatc gactgacctt ctaaagtacc cagccctagt tctcttagct
    11341 tatctgtata aaaaatctct accggacgag caagctcttt gttgatacct tctgctgtat
    11401 cacgtgctcg ctttgctgta ctggaataaa ttgctttaaa aggaacatat tttacctttt
    11461 tcccaaatgc tttgatttct tcgtaacttt gtggcaaaag cggagaatcg ccattgctcc
    11521 cttgaaaacg tctttcctga ttccattgtg tcttcccatg tcgggtaaaa tatagttcca
    11581 tacgcagcaa actcctgtct ttcttttatt ttactctata ataaactgtc taatccagct
    11641 tgtcattttc atagtgatgc gtcaattcta aattagggaa tccttgctgg cgaagtgctt
    11701 catacactat cattgcagct gtattcgata aattcaatga gcggacatgc tcatcattca
    11761 tagggatgcg taaacacttt tcttcgtttt cacgcataaa tgtttctggc aaaccggttg
    11821 tttcttttcc aaataaaaag aagtgctctt ctccatcagc aaaattttcg tcactatata
    11881 ctttatgggc aaattttgag atcaaatgta gtttacgatt acctaaaaat gttaaaaaag
    11941 cttctaaatt actgtggtaa gtaatattta catcattcca ataatccaac cctgcccgtt
    12001 ttagatgttt gtcatcagtt gaaaaaccta gtggctcgat taaatgaagc ggagtattcg
    12061 tggctgcaca cgtacgggca atatttccag tgtttgcagg gattaatggt tcaaataaaa
    12121 cgatatgatt catcaggatc attcctctca tatttatgtt cgtttctatt ttctgacaat
    12181 ttgatttttg cataaaaaaa aacgtatcaa ctcggtgtca gtcactgcga gtcgttacgt
    12241 tagtgaagct cttctcacta acttttatca gaacaggaac ctgataaaaa ccaatgaaaa
    12301 aacaacttgt tgctaatata acaccctcaa cttttttttg caacctctac tcattaaaaa
    12361 ctgctagaaa aacgttttct cttagttcct tttaataatt ctatgtcaat tgtaatcttc
    12421 ttcaaaggat tcttatataa gtctgctttg attcgctctt ctacctgcca ttctaaaggt
    12481 gacatggcca aaagatcttt ttgattttcc tctggtatct caaattcata ggttacacgc
    12541 tgacgttcag ttaatttcat tgcttcagca aacttggcta ctacacgttc attggaataa
    12601 ctctgttttt caggttgatt cggataaaaa gcctgacgta gttcctttaa ataattttct
    12661 tgtggcacca ccttcaacac ttctccatct tctgagagta cacgttggaa ttcttggtaa
    12721 tgagaaggcg aaaagatatt taaaaccgcg ttgaatgttt gatcagcaaa cggcaaattg
    12781 gtcaaatcag ctacacacca aaatgcttcg gcagattgtt ctgtagctgc gtagactcct
    12841 tcttttgaaa tatcaaatcc aacagcattt tgaatctttt tcaattttga aagttcattc
    12901 aagaagctac cttctccgca gccaacatct aatagcgaga cttcttcagg taaatgctgc
    12961 gcaatagtct caataacggg ctgatacatg ccagattgga tcattctacg ccttggaacg
    13021 aacattcctt gatcgtattc tgttttaacc gcatgggata aaaaataaag tgttcctttt
    13081 ttggaaaggt caaaacggtg attatttttg catatcaagc cattatcaga cttttttact
    13141 tcttcttggc aaaccggaca gcggaacagc tgatgatttt ctgccaaaaa ctggcgtcct
    13201 cggtcaattt tttttaacat agttccccct catttctgtt ttatcttacc gttagatgct
    13261 cactttggca actgctaaaa atatgataca atgcctagaa gaaagtgaaa gataaaggag
    13321 aagattagat gatcaaagaa ttttgcgctg aaaactacac atctattcct ctagcaattg
    13381 ctagaggagc cgatcggatc gaattgtgtg acaacttagc ggtcggtggc acaaccccga
    13441 gtactggtgt gatcgaagaa acgttaagtt atgctgggga aaaagatatc cccgtaatga
    13501 cgattattcg tcctagaggg ggcgacttcg tctataacga tatcgaattg aaaatcatgc
    13561 atactgattt gattgaagca aagaaattag ggacggatgg cgtagtattt ggttgtctta
    13621 ctccttcagg ctggctagac gaagaggcct tagaactatt gatcgaaaca gcagaagggt
    13681 tgcagatcac cttccatatg gcttttgaca gtattcctga agatcggcaa ttcgaagcaa
    13741 tcgattggct ggtagaacat ggtgttgacc gtatcttgac tcatggcggt cctgctgaca
    13801 aaactattgt agaaaatttc ccacggctta aagaattgat tgcctataca gatggccgct
    13861 taatcatttt gcctggtggt ggtgtcactg cagagaatgc agcacatgta gctaaagaat
    13921 tgaacgtaag cgaagtacac ggaaccaaaa tcgtggatct tcagttataa tcttataaac
    13981 aaaaaaacat ttgcaacagg cataatgctt attgcaaatg tttttgtttt tttacataaa
    14041 atagcccata aataaagaag caatattgaa ataaatcagt acactcgtca aatcgctcaa
    14101 agtcgtgata aagggaccgc ttgctactgc tggatcaaat cctagacgat ccattagcat
    14161 cgggattaaa ctacctgcaa gattcgccac tgtgattgca aatagcatag ccatccctat
    14221 gacaaacccc aagataaaat tatgtttcca aaaacctacg attagaaaaa tcgtgatccc
    14281 cgtaacagct cctgtgacaa cgccggtcaa gacttcagcc aaaacaagtc gaacaaatcc
    14341 atgatctttc tcatcagaaa tcgcaagtcg acgaacagcc acagctagcg actgggttcc
    14401 agcattaccg gcagttcctg taatcagcga aatgaagact gctaaaatac tcgcttcact
    14461 taccaagtct tcatagtgac tgattaaaga agcggtcgac atacctaaaa acaacagagt
    14521 gatcagccaa ggcaaacgtc gagacgctgc ctttactgga ttttcattaa tttcttccac
    14581 attgaccccg gcaagtcctg aataatcgct agcagcttca tcatcaataa cgtcgatgat
    14641 atcatcgact gtgacgattc ctaacaaatg atcatcataa tcggtaacag gaagagctaa
    14701 gaagtcataa tctctaaatg tttgtgccac atcttcttgg tcgtcgccta catgaactga
    14761 aagcactcgt tcgctcatca gatcagaaat cattgcgtcg tcatcattca cgattaggtc
    14821 gcgcagagaa ataaccccta ctagctgacc ttcttgatta acgacataga tgtaatagat
    14881 tgtttcagct acatctgctt cgttcttcag cacgtacatc gcagagcgaa cagtttgatt
    14941 ggctacgatc gaaacaaatt cagttgtcat gatcgcgcca gccgtttcat cctcgtaatg
    15001 gagaagttcc ttgatttcac tggcatcgtc tgccgacatc aaacttaaat atttagcaat
    15061 ttgcttttta tccagcgtat taagcaagtc aacagcatta tctgtataca tctcagaaag
    15121 catatcagct gcatagctag gacgcatttc atctaggtat tctttcatat gttcgttgtc
    15181 ttcttcaatc acatcgaaca tatccgctaa ttctttaggc gacagatagg aatagatcag
    15241 ctgcctgttc tcttctgtaa gagattggta gaattgcccc tgctcataga tatgcatctc
    15301 taaaaaactg tttctgaatg cctgaatatt attttccctt aaatcttgag tcaactgggc
    15361 aaatctttcc tctaattctt gattttcatc caaaccaatc tcacctcgcc ttattcttca
    15421 aaccgtctca caactgcctc catgtctgcg gctaaaggct gcttgaactc cagcaactct
    15481 tctgtaaatg gatggtaaaa acgcagatca taacaatgaa gggcttgtct ttttattccc
    15541 agatccattc gcccgccata catatcatca ccgagcaggg cacagccaat tgcggaaaaa
    15601 tgaactctta tttgatgtgt ccttcctgta tgcagctgga tatcaactaa cgcgatttct
    15661 gttagtcgct tctctatcca gtactcagtc tgtgccgaac gtccttcatc agagaccatt
    15721 cgcttcaata gcgaagaata atctcgggcg atcggcaaat cgatatgtcc atgtgccgat
    15781 aaatctgaaa gccttccact gactaaggcc tgatattttt tcacaaactt cttttcacga
    15841 agttgcatat ctaattttgc gtgcgcaaat ccatgctttg caaaaagcat caagccagat
    15901 gtatcccgat ctagtcgcgt caccacatgg attacttggt tttcgtaacc ttgtttttta
    15961 taataagcct ttacacgatt agccattgtc ccatttggat ggtattgggc aggaatagac
    16021 gaaacgcctg ctggtttatt tactaccaga acgtgttcat cttcatacac gatatcgatc
    16081 ggtgtttcat ccaaaagtac ggtttcatgt tctccttcag caggaatcac aatggttacc
    16141 ttatcatcct tagctagaga aaacaagaca ttttctactt gatcattaac tttgatttga
    16201 ccgccttgaa attttatttt cgctaacaga ccctttgaga tccctttttc ttttaaaaaa
    16261 tattttactt gctgagaatg atctttctca taatcccatg taaactgcat atcaatcctc
    16321 actaataaag gcatctttca cacgatgcca aaaatgcata tgtcgataag aagcaaaatg
    16381 gatccgttct tctgctattc gataataaat tgagcggata tttgcttttg cgacattcaa
    16441 ttgatcaacc gttacaagat aatcttctgt attttccaat tttatttcta gccattcatc
    16501 atgggcaatc acgatcggag aacccaaagt acgaaacact cgattattca gtgaagcaat
    16561 ctctgccaac tgaaaggcat tgatactagg atggatcaca gcaccgccga cacttttatt
    16621 atatgctgtc gaaccagtag gcgtagaaat cgtcaatcca tctcctctaa aactttcaaa
    16681 cagctcgttt ttgatgtata catcggctac catcgtacga ttggcccgtt taatcgttga
    16741 ttcattcagt gctaaaaaat gctggtccgg tgtttcatcc aaataactga tccgaacatc
    16801 cagcaaggga taactaacac tttgttcccg gttcgttcgt aagctgtcta ctagttcttc
    16861 cagctcgtaa tcccgccaat ccgtgtaaaa ccctaaatga cctgtatgca cgcccaagaa
    16921 acgcacatca ttcagacaat gactgtagtg atggaacgcc gacaataatg tgccgtctcc
    16981 gccgactgag atgaccaatt ctggctcatg atcatctcgt tgaatccctg cttgttctaa
    17041 aagtgcgttc aaacgttctg tcacttctat agtctttgct tctttattat gaacgatcgc
    17101 tactttcatc ccctgcctcc tctctttcgc tttctttctt caaaagcgtt cgatagtaga
    17161 catcatctga ttttcctctt ccatgggaga ataaccgctg tgcttcttgg atttcttcac
    17221 ggatactgga catctcttca tccaactgat aggcagcttc tgccgcacgc tgaagtcgtt
    17281 cactcatttc ttctggaaaa acgccttgat atttataatt cagcgaatgc tcaatcgttg
    17341 cccagaaatt catcgcaaga gtccgaatct ggatttccgc caaaattttc ttctcaccgc
    17401 tgatcagctg tacaggatac tcgatcacca gatgataaga acggtagcca cttgcttttt
    17461 tatttgtgat gtaatctcgt tcttggagaa ctttcatgtc ttttctttta cggatgatct
    17521 caacaacttg atggatatct tctacaaact gacacatgat ccttaacccg gcaatatcag
    17581 acatttcttc ttctaaacgt cccattggaa tatgccgtaa ttgtgatttt gttacaatac
    17641 tatcgactgg cttgactctc ccagtgacaa attcaatcgg gacatgtcga ttttgttcac
    17701 ggaactgttt gcggatcccc cgcagtttca ctttcaattc tgatacagtt tgttcatatg
    17761 gtgctaaaaa tgcttcccaa tctcgttcca tagctgatac ctctacttca ttaacattca
    17821 ttgtttattc taccatatat gcaaagtttt ttcgtactct tgatttatgc attgaccaaa
    17881 aaaagaaaat taggcaaaat agacaaaaag gagtcgatca aatgacacaa atgcttgaaa
    17941 tcgaatataa atctatgctg acaaagcaag agtacgagat attcatcgct cactatcaat
    18001 taacagataa agatttccgt gtacagacta atatttattt cgataccgtt gatgaacagc
    18061 tgaagaaaca aaattgtggc ctacggatcc gtttcgttgg tcatcaagct gaatatacat
    18121 taaaaacacc tgctgaaaaa gggcgtctcg aaacaacgga tacctttata acagaagaag
    18181 cagaagcatt tatcttcgaa aaacgtctgc ctcgttcagg cgcagttttt caaaaacttt
    18241 ctgatttgaa tatcgatcct gcttcattaa tccaaaccgg aaagcttaca acaaaacgag
    18301 ctgaattccc tattgaagaa ggacttttag ctattgatga aagctgggga gacaatctac
    18361 acgattttga actggaacta gaggtagggg atgcatctgt gggaaaaatt gcttttataa
    18421 attttttaaa acgtttttct ttaccttatc gtcctgctaa gaacaagatc caacgtatgc
    18481 ttgaagctaa aaattagaaa cctttcattt tcacaaggca cttgagttca tttttttact
    18541 tttttctgtt aagttatagg atgtgaaaga atctagtcac tagttgtata gaatctattt
    18601 tgggggagat tcatatgatc gaaatctatt tatttgttaa tcctttaggg gaatactgtt
    18661 tcgaaatgga acaacagtta ttacaattta tcgaagaaga gtacgggaca ccatcaaaag
    18721 aaaagatgca atttcgcttt cttcctttgg tcaatttgca gacaattggg gatgtcatgc
    18781 aacaaaaagg aatttctcag aacaatcttg aggaacgtaa tcacttattc tcaatgactt
    18841 attctgcagc attggactgc aaagcggcgc agtttcaagg aaagaaaaaa ggccgccgtt
    18901 ttttgatcaa attgcaagaa gcagtcggct gtaatgacat accatattct caagaacttg
    18961 ctgaatccat atttgaagaa atcggcggcg atttgaatat gtttaaagaa gatcgtcagt
    19021 ctgacttcgt taaagaagta ttcttttctg atcaaaaaat tgctcgggaa atgggcatca
    19081 caaaacaccc ttctgcagtc gtttacaatt atgcctgcga ccgtgatttt ggtgttttag
    19141 tagaagtaaa aggtacaagt agcctttgga gaatcacaga gctgtgtaaa acaacagata
    19201 actcatatca agtttttaat ggtgaacatt tacatacaaa tgattctcag ttccattcaa
    19261 gaactagcca tttacacttg ctttctaatt aaaaaaggct ctttgtcaaa tgatgttggt
    19321 aaagagaaat cttagaataa tttggacaga acagaaagaa gaaaacctct ttctgttctg
    19381 tttatttggt taaaaatgtt ttgccatgac gaatcataat tcgtagtttg aaattgtaaa
    19441 agttg
//
LOCUS       DADVXK010000048        19199 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.048, whole genome shotgun sequence.
ACCESSION   DADVXK010000048 DADVXK010000000
VERSION     DADVXK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.048"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(541..1566)
                     /locus_tag="KB909_001595"
     CDS             complement(541..1566)
                     /locus_tag="KB909_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6837618.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1841..3526
                     /locus_tag="KB909_001596"
     CDS             1841..3526
                     /locus_tag="KB909_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBB6837619.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3540..4823
                     /locus_tag="KB909_001597"
     CDS             3540..4823
                     /locus_tag="KB909_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6837620.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4893..5762
                     /locus_tag="KB909_001598"
     CDS             4893..5762
                     /locus_tag="KB909_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6837621.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5759..6595
                     /locus_tag="KB909_001599"
     CDS             5759..6595
                     /locus_tag="KB909_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837622.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6621..7688
                     /locus_tag="KB909_001600"
     CDS             6621..7688
                     /locus_tag="KB909_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBB6837623.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7685..8512
                     /locus_tag="KB909_001601"
     CDS             7685..8512
                     /locus_tag="KB909_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6837624.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8557..9582
                     /locus_tag="KB909_001602"
     CDS             8557..9582
                     /locus_tag="KB909_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6837625.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9579..11762
                     /locus_tag="KB909_001603"
     CDS             9579..11762
                     /locus_tag="KB909_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6837626.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11762..12892
                     /locus_tag="KB909_001604"
     CDS             11762..12892
                     /locus_tag="KB909_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6837627.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12889..13566
                     /gene="pgmB"
                     /locus_tag="KB909_001605"
     CDS             12889..13566
                     /gene="pgmB"
                     /locus_tag="KB909_001605"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6837628.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13650..14177
                     /gene="msrA"
                     /locus_tag="KB909_001606"
     CDS             13650..14177
                     /gene="msrA"
                     /locus_tag="KB909_001606"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6837629.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14378..15064)
                     /locus_tag="KB909_001607"
     CDS             complement(14378..15064)
                     /locus_tag="KB909_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBB6837630.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15144..16682
                     /locus_tag="KB909_001608"
     CDS             15144..16682
                     /locus_tag="KB909_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBB6837631.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16802..17269
                     /locus_tag="KB909_001609"
     CDS             16802..17269
                     /locus_tag="KB909_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBB6837632.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17788..18231
                     /gene="rplM"
                     /locus_tag="KB909_001610"
     CDS             17788..18231
                     /gene="rplM"
                     /locus_tag="KB909_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBB6837633.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18247..18639
                     /gene="rpsI"
                     /locus_tag="KB909_001611"
     CDS             18247..18639
                     /gene="rpsI"
                     /locus_tag="KB909_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6837634.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18727..>19199)
                     /locus_tag="KB909_001612"
     CDS             complement(18727..>19199)
                     /locus_tag="KB909_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6837635.1"
                     /translation="TVRLKHTLDKYQRKKFTKGRKDTVIQVPEVVMTLLSEWKSVQAD
                     QLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRINSIKRRHPDLVHLSPHKLRH
                     TYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIVDKAVFEAFQRGLNKCD"
BASE COUNT         6225 a         3482 c         4102 g         5390 t
ORIGIN      
        1 gtctaaaata atttgtctaa ctagaagaaa agtgggaaag gatcttaaca acatcggttc
       61 gtatccaatt aaggtatcgg aacgatcatc ttccaagaga agtcaatcaa caaaagtaaa
      121 gatagatcat tttttgaatg caaaataaat tgatgggaag atagagcggt tatttttaat
      181 attttgctag ctattattga ataattcctc gaataaaaca aaaccagtag acatgtctgt
      241 tattctattt atgttttaga gataagtatc cccaaataac atggattgaa ataagggtaa
      301 atgtgtttaa aaaaacgaac tataaaaact tatacacaac gtggttaaaa atagtttttt
      361 cttccctgtg gaaaaaatag tttaacacaa acattatagt tatccacagc tatctaaaac
      421 agatggaaaa taagaaaaat tcgctaaaat accgggaggg ggtaacgagg gatgagtgat
      481 tgaaaaaaga acagagtaac tgacttatcc tcagtgtttc tgttctttta taattctgtt
      541 ctacatttct tgttgttgga tcgaatctgt gagagtaatc tcggttgaaa gaatgattct
      601 tttttcttca gggtattggt ggtggattag ttggaataaa agttctgtgg ctttgattcc
      661 taactgattt gtcggaatgt ctatccgagt caactgtggc gaaaataggg aggacaataa
      721 gggatcactg aatcctgcga tcgaaagatc atcaggtatc tgctttccag attgttctgc
      781 cactttgtaa atactcaatg attttaatgc atcggtagaa aaaatcgcag ttggtctttc
      841 tcgtagcttc attaaatcat tcattgctgc catgctatct tctaagcgaa agccgccgtc
      901 tataatccat tcattacgga tatctaggtg gtgatcaaat aagcattgac ggtaaccatt
      961 gagacgatca ttggatacat aaacttctgt cggagcatgg agacagccga tatgacggtg
     1021 tccattcttg atcagtgttt ccaccaaatc gtaactatcc tggaaattat ccgtgtccac
     1081 tgagtagatg ttcgtgtagt cgtttccgac ttttccgatt accacaatag gaatattgta
     1141 ttgatccaat tcaaaaagaa gtgtttcatc catcgtagag cttaaaataa taattcctcg
     1201 gatcattttt tcttggatct ttttcgcgca tttttctagc tcttcttctg gtgtttttgc
     1261 cgtttgtaga atcaagtcga agttattttg ttcagaaacg gcagaaatgg attgaataac
     1321 atctgaaaaa aaaggattgc cataggtcgt atgagaagta cgatgagata atgctagaat
     1381 cgcgtcaaaa ccatttcctg acagtcctct tgcaattttg ctcggttcat aattcaattc
     1441 tttgattgct tgaagtacac ttgcttttgc tttatcagag atatttggct ggttatttaa
     1501 tactctggag acagttgatt ttgagacatt agcttttttc gcaatgtcat aaatagtagg
     1561 tttcaatttt atatgcacct cctttttggg agcgttttag aataattcca tagtacaata
     1621 gacattcttt tttgtctatg attttgaaaa tttaggaata gcttgcatga tcatgagaga
     1681 ccatattttt ttaagaagct attaattatt gatacataag ctttcttatt tgtatttttg
     1741 tgtatatcaa aattatttaa aaaaatgcta ttgacagtaa gcgttttcca taatatgatc
     1801 aaatcgttgg gaacgctccc aaaaaagaaa ggggaatccg atgtatacaa aacttttaca
     1861 agcgatttat cgcgactcag atttgtctga gaaaaccgcc tctatgattg aacaaaaagt
     1921 cagtgtttat cagcagaaga aaggccaggc aggcaaactg cattgggacg aagaagatat
     1981 tttcttgatt acttatgggg atcaattttt tgaagagcag caaccaactt tgcgtacatt
     2041 taagaaattt tatcaaaagt atttggcaga tacatttaga gttgtacatt tcttgccatt
     2101 tttcccatat acatctgatg atggtttctc cgttgtaaat tatcaggcaa tcaacgaccg
     2161 tttgggcaca tgggaagata tagaagaaat gagaagcgaa acacggttaa tgttcgactt
     2221 tgtctgcaat catatgtctg ccgaaagtac ttggtttcag gaatatttaa acttgaatga
     2281 tacgtacaaa gattttttta ttgatttgcc actggataca gatacaagca gcgtgactag
     2341 accaaggacc agcccgttac ttacaacgtt cattgacaaa aacgggaaag aaaaacacgt
     2401 atggacgact tttagcgaag atcaagtaga cttgaatttt aaaaatccag aagttttatt
     2461 gaaaatgatc gatattcttt tgttttactt agaaaaaggc gcttcattta ttcgcttgga
     2521 cgctgtggga tttttatgga aagaactagg aacttcttgt atacacctgc cagaaacgca
     2581 taaaatcatc caattattcc gtgcaatcgc tgatgaagca gctccaggaa cggtattgat
     2641 cactgagaca aatgtgccac acaaagataa tatcagttat tttgggaatg gcgagaatga
     2701 agcacagatg gtctatcagt tttcgctacc acctttgacc cttcaagcga ttcgttcggg
     2761 taatacaagt aagttgaaag aatggttaaa aaccatcgat ttcgcatcga aaaaaacaac
     2821 tttttttaat tttttagcct cccatgacgg tatcggattg aatccggtac gaggtattct
     2881 gccggaaaaa acgatccttg aattagtgga acagctgaag aaagagggta cccgagtaaa
     2941 ctacaagaaa aacccagatg gaacgaccag tccatatgag ataaacgcta cgtatctaga
     3001 tgcgttaagt tctccaacag atacgacgga atggagaagc aaacgctttt tagctgctca
     3061 ttcatttttg gtaacgttac caggcgtgcc ggcaatttat attcaaagtg tgctgggaag
     3121 tcgaaatgat tacaaaggcg tagaaaaaac aggagagaat cgaaaaatca atcggcaaaa
     3181 atttttgtta gcagatattg agaaagagtt gcagacagat ccattaagaa cagcagtata
     3241 tggtgaattg acccagatgc tatctattcg aaaaaaagaa aaagccttcc atccgaatag
     3301 tttgatttac ttactggact cagcagattc ttttatcagt tttattcgcg aagcgaagga
     3361 agagaaagtc ttagttatcc ataatttttc caatcaatca gcaggttatc ttttaccaaa
     3421 aggagattac ctagacctgt tttctggaca aattatccat tgcagtcaag aacgaaagtt
     3481 gatattccag ccgtatgaat atatgtggct gaaaataata aaataagagg tggaaaaaaa
     3541 tgaaaaaaat tattgttact acctgtctgc tagctactgg atttcttctt actgcttgtg
     3601 gtgaaagtca aagctctaac gaatcacaac agacaacgat tcaattcatg cactcttctg
     3661 tcgaacagga acgattaagt gtgatcaatg aactggttgc tgattttgaa aaagaaaatc
     3721 cagacatcaa aatcaagcaa gtgccggtag aagaatcagc gttcaataca aaaatcgtta
     3781 cgttagctcg ttccggtaaa ttaccagaag taatggaagt cagtcaggat tttgctaaag
     3841 tgatggataa agatgaactg attgatcaga cggcagtcca aaacgttatc gaggaagctg
     3901 gagaagataa ttattatgac ggagccaaaa accttgttcg ttcagaagat ggaaaaagct
     3961 atattgctgc accaattagc ggctgggttc aaggtatttg gtatgacaaa gaaaaattat
     4021 cagaagctgg tttttcagaa ccagaaaatt gggatgatat tttaaaaatt gctcaacatt
     4081 tcacagataa agagaataaa caatatggaa ttgctatgcc tactgctgaa ggaacaatga
     4141 gtgagcaagc gttctctcaa tttgctttgt caaatggagc aaatgttttg gatgatgaag
     4201 gcgaggtaac gatcgatacg gaaaagatga gagaagcatt gtcgttttat caaaacttat
     4261 cccaatacac gatgccaggc tctaatgatg tgacagaaat caaagatgct ttcatgaatg
     4321 gaacagcacc aatggcaatc tattcaactt acattttgcc ttctgtttat gaagcgggga
     4381 actcagaaaa tatcggtttt gctatcccaa cacaaaaaga tcaagctgtc tatggcacag
     4441 tatctggatt gacgatttct tctggtctag acgagaaaca aaaagaggct gctgaagcat
     4501 tcacagcttt cttatctcaa ccgaaaaaca tggaaaagtg ggtcttgatg tctcctggtg
     4561 gtgctcaacc agtgaataaa caagtagtcg aactggatgg ttacaaagaa aatgaagtca
     4621 tcaagtcttt tggcgagctg ccatctgaga ttgctagtgc ttttgatgaa gtacaagtct
     4681 ttggactagt cggggaaaag aatttcacga aaatgggaga tatcacaagc tcaggtgtga
     4741 tcggaaaagc agtgaaccaa gtaactgtcg gaaacgaaga tgtcgatcaa gctttagctg
     4801 acgcacaaaa aaatacgaaa taacaagaag ttctgccaat ggtgttcgaa aaaagtagat
     4861 agctattggc agattatcag ggggaggttt caatgaatcg tccaaggaaa cattctgact
     4921 taaaattagc catgggactt ttagcaccaa gcatgctttt attagctgtt ttagtgctga
     4981 ttccaatgct ttccaatatt cagatcagtt ttttcgatat gccgctgaat cctaactcag
     5041 acgccgtttt tatcggatta agcaattatc ttgaaatttt aagtgatagt gaattttatc
     5101 gttctttagg tttaacagtt gcttacacat tcttagttgt agcaggcagt acagctttag
     5161 gattagccgt agctattttg cttaaccgca agttcagatt taggaaaacg gtgcgttcac
     5221 tgattttatt aagttatgtt acgccatcta tttctttgat ttttgcttgg aaatatatgt
     5281 tcaataatag ttatggaatc gtcaatgatc tgttagtaga taggttgcag cttttcaacg
     5341 aagcaccgct gtggttcgac cagccagttg ctagcttctt tatggtcgtt ttgtttgcta
     5401 tctggagata ctatccgtat gcgtttattt catttttggc tattttgcaa acagtcgaca
     5461 aaacgcttta tgaagcagct gaaatggacg gtgcaaatgc ttggcagaag ttcaagatcg
     5521 tgacactgcc ggcaatcaaa ccagtactag caactgtgat tgttttacga tctatctgga
     5581 tgttctatat gtttacagat gtctatctac tgacgaataa agtcaatatc ttaggcgttt
     5641 atttgtatca gacagccttt gcgttcaatg atcttggaaa agcagcagct atatcgattc
     5701 tattgttcat cattattgca gcggtcgtct tgctctcacg aaagaaggtg gacttgaaat
     5761 gaaaaataaa aagagcagga aaatcttatt ttacgcgacg attttgttgc tattagctgt
     5821 caatttgttt ccatttttga tcatgctgat gacatcattc aaggattcac aagaagcaat
     5881 tgcaacgaca caaactattt ttccgaaaga atggactttt gaacattatc aggatatttt
     5941 caatgctgag atttttccat tcatcatgta tttcaaaaat agtttagtga tctccttgat
     6001 agcctccgta actgcagtag tgattgggat cagcggggca tacgctttgt caaaactacg
     6061 cttcaaagct cgctcgaaaa tcaatgctag cttttacacc gtttatatgt tttccggtat
     6121 tttgatcgtt gttccattat ttaaaatcat ttccggtcta ggtttgtatg ataccaatac
     6181 agcactgatt atcacgatgg tcgttcaaac acttcctact gcgatattca tgctaaaaag
     6241 ttattttgac acgattccga ctgatattga agaagcagca atgatcgatg gtcttagccg
     6301 gatccagatc attattcgga tcattatacc attggctatt tctggaatca tttctgtctt
     6361 cgtttattgc tttatggttt cgtggaatga ttatttattt gcttcgattt tcctgtcgac
     6421 ctccgaaaaa tttactttac caatcggttt gaacacatta ttcagtacac cagactacat
     6481 ttggggacga atgatggccg cttcattggt gaccgcttta ccagtcatca ttatgtatgc
     6541 gttatctgaa cgatttatta aaggtgattt agtcgaaggc ggcgtaaaag gataaaaaga
     6601 aaagaaagag gaaagaaaag atgaaaaaat tagttgcatt agaaccaaga atagccggat
     6661 tcaaagatta cgaagaccgt gagatcgaaa agaacgaagt acgtatccga gtaattttcg
     6721 ctactccaaa accaggaaca gaaattgtcg actttagagg attaagtcca tttatcgatg
     6781 aagaattttc agaagaatgg cgcctattct tgccaagaga agaaggaagc caacgcggtg
     6841 tggtatttgg cgaatttcaa ttaggaaata tgattgtcgg tacgatcgaa gaaacgggca
     6901 gtttggtgac agagtatcaa aaaggagagt tagtctgcac ttatggaccc attcgtgaaa
     6961 cgctgattac aaacggtgtt gataattata aactacgtaa acttgatcgg ttggatcaat
     7021 ggaaaaatgc agtatgttac gatcctgctc aattcgcttt aggtggtatc cgggaagcac
     7081 atgttcgagc aggtgatgct gtagcaatct tcggtttagg cgctatcggg caaattgcga
     7141 ttcaattagc taaaaaagca ggtgctacta ccatcgttgg gatcgatccc atagcgcagc
     7201 gtagagaatt agcagaaaaa tacggtgccg attacacgct agatcctatg aaagcagatg
     7261 tcggttttcg tctaaaggaa ttgacagata aacgtggagt agattcagtt attgaaacga
     7321 gtggcagtgc tgccgcatta caagcttctt taagagggat cggctatggc gggatcattt
     7381 cttatgttgc ctttgctaaa ccttttccag ctgggtttaa tcttggtcgc gaagcacatt
     7441 tcaataatgc aaaaatcgtc tttgctcgag catctagtga accaaaccca gattacccaa
     7501 gatggaaccg taaacgaatc gaggacacat gttgggaatt attgatgaac ggttacttgg
     7561 attgtgaaga aatcattgat ccagttgtgc catttgcaga aagcgcagaa gcttacatgc
     7621 gttatgtaga ccagcaccca gaagaaagta tcaaaatggg cgttcaagtc cgaggaggag
     7681 aacaatgaaa ttcggtacgc aagatcaagc atttttccca agagacattt tagaaaaatt
     7741 tagatttatc aaagactgtg gatttgaaga atacgaaatc gacggtaagt tgttaataga
     7801 aaatatcgac acagtcaaac aggcaatcaa agaaacaggg atcccagtag tgacagcttg
     7861 taacggctac gatgggtgga tcggtgactt tatcgaagaa cggcgtctta atggtgtacg
     7921 tcaaattgct gagattttgc gtgcactaag cgaggttgga ggcaaaggaa tcgttatccc
     7981 agcagcttgg ggaatgttca cttatcgatt accgccgatg gtttcacccc gaagcaaaga
     8041 aggagactat aaagcagtca gcgaatcact tcgttattta gataaagtag ccgaagaaac
     8101 aggtacggtt atttatttgg agcctttgaa ccgataccaa gaccatatga tcaatttgtt
     8161 agcggatgcg cgtcattaca ttgactctaa tcaattgaaa catgtgcaga tcatcgctga
     8221 tttttatcat atgaatattg aagaagatga tatttcaaaa gcattgacta cgcaaaaaga
     8281 gtatgtgggt catatccatt tagcagataa tcatcgctac caaccaggat ctggcgcaat
     8341 tgattttact cgccattttc aaacgctact tcaaaatgag tatgaaggtt atatggtata
     8401 tgaatgtcgt ttgcgaggag aaaatgaagt gaaaatttat caggaatcat tgcaatactt
     8461 gaaaaactgt ctggaaacag cgcgtcattt aaatgattta gagaaagaat agagaaagaa
     8521 taacaataag taaataagca aaggagggag aaataaatga agaaagtagc aatcataggc
     8581 gctggacaag tagcagaaaa agtacatgct gcttattatc aaaaaagatc agatgtctta
     8641 gaattggccg ctgtggttga tccagtcagc cagcgagcag aagacttttg ccgacgtaca
     8701 ggattttctc atgcgtatac atcagttaca caaatgctga atgagatttc tcccgatatc
     8761 gtgagtgtct gtacacccaa tcgctttcac ttcgaacatg tattggctgc cctcgaagct
     8821 aatgcttcag tgatgtgcga gaaaccacca gctatgacag ctgatcaagc aagaaagatg
     8881 gcagagacag ccgataaaaa cgggcagatt ttggcttatg gattccagca tcgtttttct
     8941 gacgaagcaa caatgatcaa gaatcatctt gatgttctcg gggatattta ttacgtagaa
     9001 gcgaatgcgc ttcgtcggtc tggtgttcca ggctggggaa cgtttatcga caaagaactt
     9061 caaggaggcg ggcctttgat cgattatggc attcacatgc ttgatacagc gatgtatatt
     9121 actggatttc ctaaagtaaa aagcgttcgg gcgtacagct tccaaaaaat tggtacgaaa
     9181 aaaaattcag ggaaattcgg gaaatgggat ccaagcaaat tcacagtaga agatgcaatt
     9241 tttggcacac tggaattaga aaacggcaag atcatccaac tgaatacttc gtttgctttg
     9301 aatatcagag aagacaaact gaatgtggct ttttgtggcg atcaggcagg tgctaatctg
     9361 tatccaggcg aactattcga agatgtagat ggaaagctgg tttccttaca aaagaccacg
     9421 ccagttaatg acccacatga actaagtatg gctcattttg tgaatcgggc gctcggtgac
     9481 cagactcaga tgattgcaga tggctggcaa ggatatgtca tccagaatct ggtggaaaat
     9541 ttatatcgtt cggcagaaac aggagaagtt attaccttat gaaagtagaa gaaaaacagt
     9601 ttgatttaga gtatatcaat aagtatgcga gtcagatgac cattggaaat ggattttttg
     9661 gtatcagagg aagccaggag gaagactatc ggaatcaagt aaggggaatg tttgcagctg
     9721 gtgtatataa ccgaccttta ggagcagaat cagccgagtt agtgaatctc ccagatgtca
     9781 tcagatggga aataaaaatc gacggtgaac atttttctct tgagacgatg aaagttcttg
     9841 catacgagcg ggcactagat ttagaaatgg gagagcttaa acgctatgcg ctcattgaaa
     9901 ctgctcaagg aaaaaaagtg gaagtcatta cttgtcgtgt tgctgatcaa aataatctcc
     9961 atcaggcagc cctgaaagtg gtcatcaagc cgttgaccga agactgccaa gtagatgtga
    10021 aaacgggtat cgatggacag caaaccaatt ttggtacaca gcagttggtt gaaaaagaac
    10081 tgcgagtatt tggtgacgat ttgatcagtg catcctacca gacaacagaa agtaaaattg
    10141 atattgggat tgcagctaaa ttcaataaag caggtgtatt ccaagcaaaa aatcgccgga
    10201 tcaccgcttc cttttcagaa aagatcagaa aaaatacgtc ctttacgctg gagaagatca
    10261 tcgtgctctc tacctctctt cagcaaacag acccgtttaa gaaaagtatt gcccaagccc
    10321 agaaaagcgt tagttataca gaaattttag agcagtcgat gtcttattgg acagattttt
    10381 ggcatcagca tcggataacg atccaaggcg attcttcttt cgatcagtta gcgatggact
    10441 tcgctgctta ccatttacag attatgactc cccgcaatga tccaagtgtt agtgtagggg
    10501 cgaagggact aactggcgaa ggttataaag ggcatgtttt ctgggatacg gaaattttta
    10561 tcctgccttt ctttttatat cagtttcctg aagtagcaaa gaatttgctg ctgtaccgtt
    10621 atgatcgatt agaaggcgca cggcaaaaag caagagatta tcactatcaa ggtgcacttt
    10681 tcccatggga aagcgcacac actggtcagg aagagacacc caaatttgct gcattgaata
    10741 tcaaaaccgg aacaagacaa gaagttgctt cagctgccgc agaacatcat atcagtgcag
    10801 accttgctta tgccgttcaa gagtatgtcc aagcaacaga ggatcaatcg tttttagaaa
    10861 caaagggaaa aacgctcatt catgaaacag cagctttttg gctgagcaga gctgtaaaag
    10921 tcgatgatca tttagagata cacagagtca ttggtccaga tgaatacaca gaatatatcg
    10981 acaataatgc atatacgaac tatctggcgc attataatgt ggccttagct gttaaatatc
    11041 aagctggcga tccgcttttt ttgaaagaat gtcaaaattt tttagataag ttatatttgc
    11101 cagtgcctaa caaagaacag ctgattccgc aagatgacac gtatctcagt aagccagtta
    11161 ttgatttgac cacttacaaa gaacgtcctg gcagccagtc tattttactt gattatgccc
    11221 gtagcgaagt aaatgaactc caagtcagca agcaagcaga tcttgtcatg ctgttatact
    11281 tattacctga gtatttttct caaccaatcg tttctaagaa tttgcattac tatgaaaaca
    11341 aaacaatcca cgactcatcg ttgagtaaag cgattcacgc catagaggct tgccgtatcc
    11401 aagaaatgga atgggcgtat catttattcc aagaagcgtg cctgattgat ttaggaccag
    11461 atccgcattc atcagatgac ggaattcatg ctgcttcatt aggagcacta tggctagcag
    11521 ttatatttgg tttttcaggt attacagtaa cgaatggaac tctttctatt tctccaagac
    11581 ttccttcagc atgggaaaaa atttcttttc cttttatttg gaaaaatcac aggttgctat
    11641 ttgttttgac aaaaaaacaa atagtaataa aaaaagagac gaaagaaaca ttacctattt
    11701 ttgtcaatgg agaccaatac cagctggaaa aagaactgat cttggaacgg aggggaaaat
    11761 aatgcgtatt ctgattgcgc cagattcttt caaagaaagt ctgacagcct tagaggcagc
    11821 acaagccatt caatcaggtt ttcaagaagt ttttgttcag gctgaatatg atctgctacc
    11881 tataggcgat ggaggagaag gaacggtttc atcattagca gacagtttaa ggttgaagcg
    11941 gcaaacagca gtcgttacta atgcatttgg caaaaacaaa gaaatccagt acgcttcaga
    12001 cggtcaaact gcgatttttg aaatggcaga aatcgtcgga ttgaaagatg tcccactaaa
    12061 ccaacaacag ccacttaggt tatccacgcg aggagtagga gaactgatac gacaattgtt
    12121 gcaacaaggt gttcgacaca tcatcatcgg cgttggcgga agtagtacca acgatggcgg
    12181 catcggcatg gcagaaggtc taggttatgc tttttacgat caagataatc aaaaagtaga
    12241 agcactggga gaaaatctag gtaaaattgc tacagttgat aaaacgaacg tgcctattga
    12301 gctgattaaa gccaaaatca ctgtcattac tgatgttact aatcttttat gcggaaaaga
    12361 aggcgcttct tttgttttcg gaccacaaaa aggcttgaaa gaaaatgaat tagcagtggc
    12421 tgaccaagcc atgcatgatt tttatatgag atttgcccct caagtaatcg aggcatcggg
    12481 cagtagtgct ggtggtggaa tgggtgcagg actgttagca tttgcttcag ggaaaatagt
    12541 ctctggcatc gactacgtat tggatttact ggagttcgat aaacgggtac agcaagcaga
    12601 cctcgtaatc gtaggcgaag gacgtctaga tggacaaagt ctaaaaggaa aagcgccagt
    12661 tgggattgct agaagagtac cagagggcgt tcctgtgata gctatttgcg gaagtgttgg
    12721 taaaggaagc gaaaaagcag cagatgttgg catttcggcc gtttttccga tccttcctgc
    12781 agctgtgcct ttacaagaag ctttacagca agccactgat aatcttcatc gcacagctaa
    12841 aaacatcgca tctttacttc aagtcgttca ttttcaagga ggtaatcgat gaaaatcaaa
    12901 gcagcactat tcgatttaga tggcgttctt gtagacacag ctcgttatca ttacgaagcg
    12961 tggctggttt tagctaacca gctgtccatt ccattcactg agaaagaaaa cgagcaactg
    13021 aaaggaatat ccagaaccga gtcactagag cgattgctgt catttggaaa aatggaacag
    13081 aaattctcag aaaaagagaa atcagccttt gctgagcaaa aaaacaatct atatcttcaa
    13141 gcgattcaaa aaatggatga aacatccgtt ttgcctggtg caatagctgt tcttgagtac
    13201 ttgaaaaaaa caaacatcaa gatcggattg ggatcagcaa gcaaaaatgc acgcctcatt
    13261 ttagaaaaaa cgaatttgac aagttatttt gatgtcctta ttgacggcac gcaagtatca
    13321 aaagcaaaac ctgatccaga agtttttctc aaaggagcac agcaattgaa tgtaccgcca
    13381 aatgcatgct tggtcattga agattcagaa gctggttgtc aagcagcttt ggctggtaac
    13441 atgcatgtat tgggaatagg tgaaaacata aatcttcctt ctgctgaata tgtgattcct
    13501 gatttaaccg tttttgatca agtacgttcg ttttggcatt tatcagaagc cgtatcacgt
    13561 atataatagt ttccgttttt tctgtcacaa gcaaaacgtt atcctccttt tggaaatcaa
    13621 ggtatgatga gaaaaaaggg ggattttata tgacaaaaaa agcagttttc gcaggcggat
    13681 gcttttggtg tatggtcaaa ccatttgaag agcagccagg gatcatttct gtgacatccg
    13741 gttatactgg cgggcatgta ccaaatccaa cttatgaaca agtaacaaca ggcacaacag
    13801 ggcatacaga agcagtagag atcgaatatg atccagaagt tatttcttat gatcagttgg
    13861 tggaaatcta ttggcagcaa accgatccga ctgacgcatt aggacagttc gctgatcgcg
    13921 gtgattctta tcgtccagtg atctactata atgatgaaga agaacgaaat attgcagagc
    13981 gttcaaaaca agcattgcaa gacagcgggc gattcgataa gccaatcgtg acaaaaatcg
    14041 aaccaagaag cgaattttat cctgcagaag attaccatca ggattattac aagaaaaaca
    14101 agctccatta caatctttat cgagaaggtt ctggacgtgc aggtttcctt cgtcgacatt
    14161 ggggcgtcaa gaaataagaa gccgaaaaag ctacttatgg aacaccgtat atcagaggtt
    14221 gtaaaaccag cattttgagc taatactgag ggtcagctga ttgaacacca tttagtggag
    14281 aggttgtgaa cctgtcgcct agctccaagt cacaaggatt tggtaagaga acactatata
    14341 tcagaggttg tgacaagtcg tttgtcacaa ccttttttca atacctaaga tgaaggacaa
    14401 tcagcaacgc actgctcaaa aaaggaatga aaggcagctt ttccaacttt tttttatgac
    14461 agataaagta aacagaaaaa acggatattc caaacagact agcaagaaac aagatctgaa
    14521 gcaactcttc tagagacaag ccaccactcc aagaaagcat caacagagta tcgccagctc
    14581 cgagatagga ttgaccatag cgaaggcaca caccgcctac gataaacgtt aacagcacac
    14641 tttgccattg gaagacgccg gcctgcaacc aaaaaatcca taaaattgcc caagaacaga
    14701 atagcgtgtg agaatggacc atgaagtaaa ataaatccat caacgaaaat agcaaagccg
    14761 aaagcatcca tatgaacgtc gaaaaatttc ttgcggaaga aaaagtaaag aaccaggcaa
    14821 aaagaccacc acataaggct tctgccaaca aatagtagaa gggcaaccga cacctgcaat
    14881 agcggcagcg aaatcgttgg acgatgatcg agagaatcgg aatcaattca taccaagaaa
    14941 gcgaacgaca gcatttgaca caatgagatc taggataaat aatagagtga cctaacggaa
    15001 tccgctgggc ggttaaacat aaaaatgatc cgatacagca accaatgata aaataaagta
    15061 acacgccatc tccccctttt caaaaccaag atacgcaagc ttaaactaaa tttttgtaca
    15121 tacataaaat ttgaggtgaa aaaatgaacg tttcaatcgg attagatatc ggaaccacac
    15181 aaaccaaagc agttgctttc acagatgaag cccaagaagc agcatccgct tattttcgct
    15241 accctttgat ccaagaaaca caagggatgg cagaacaaga tcaggaattg atctttcaag
    15301 gtgtctgcac cgttataaaa gaagtaatta aacagttgcc ttcagacaca atcattcaat
    15361 ttgtctcctt ctcctctgcg atgcatggcc tgatattgtt ggatgaagag aaaacaccgt
    15421 tatctcgaat gatcacttgg gcagataacc gagcagcgga cgaagcagaa aaactgaaat
    15481 ataccgtgct tggcaaagaa ttttatcggc agactgggac gccgattcat ccaatgacac
    15541 cattgaacaa aatcaagtgg ctgcaaaaca gccaacctga attattcaaa aaaactgctt
    15601 attttgtcgg tatcaaagac tatatctttt atagattgtt tggcgaactg atcagcgact
    15661 acggaacagc ttcaggaact ggatattttg atatccatga attccaatgg gcagaagaag
    15721 tgcttgacta cttgaacatt cgaatagagc aattgccgca agtctttcct tccacctatc
    15781 aagtaacagg tctaccatca aaaacagcag cagaactagg tttgccaaat gatatatcat
    15841 ttgttttggg aggggcagac gggccgcttt ctaatctagg gttaggtgct tttggtgata
    15901 cgatcgccgc tttgaccgta ggaacgagcg gagcacttcg ttttattact actcagcctc
    15961 agttccatcc agaaatggag acgttttgtt atgttctgga tcagaaacat tgggtagtgg
    16021 gaggagcgac tagcaatggt gctggcatct ttgattgggc agggcataca tttttacagg
    16081 aagtcgttca atctgctaaa gaaaaaggag aaaatccata tgatgcactg ctttcggcta
    16141 tcgcttttgt gccagcgggt gccaatggtc tgatttttca tccctattta cttggtgagc
    16201 gagcaccgct ttgggacgca gatgcgtttg gcagttttat cggtttacag cggcaacata
    16261 cagaaaaaga aatgatgaag gcgattctag aagggatctg tctcaacctt tatcggattt
    16321 taaaaggagt ttgccaggaa aatcagctca cagagatccg tgctacaggc gggtttgctc
    16381 aatctccgat ttttcgtcag atgatggctg atgtactggg ttacccgctt gttttcccta
    16441 ctgtcacaga agcatccgca ttaggagctg tgattttagg ctggagaagc atcggaaaga
    16501 tccaaagtat cagtgaagca caggaattga tagaattgaa agagcaagtt ggagtacaag
    16561 aaactgatca taaaaaatat cagaaaatct atccattatt tgtttcgaca caaaagcatt
    16621 tagcacagac ttatcagcaa tttgctcaac tgcgagaaga attagctgat tctgaaaaat
    16681 gattggcttt acggataaaa aagcgaactg aaaatcgttc tcaggtaaat gattttgttg
    16741 tacttttcat tgaaagtcta ctattatttt aagtgtaaga aaatgttagg aggcaagaaa
    16801 gatgaaattc caacaaacca aagaagtatt aaatcaatta gttgcagatc taagccaaat
    16861 gtctgttgtt gttcaccaaa cacattggta catgagagga ccaggtttcc ttacattgca
    16921 cccaatgatg gatgagttca tggatgattt gaacgctcag ttagatgaag tatccgaacg
    16981 cttgatcaca ttagacggtt caccttattc tacattgcgt gaatttgcag ataacacaaa
    17041 aatccctgat gaaattggcc gctgggatcg tactattcca gaacgtttgg aaacacttgt
    17101 tgcaggctat cgttatctag cagatcttta ccaaaaagga atcgaagttt ctggagaaga
    17161 aggcgacgat ccaacacaag atatctttat cgaattcaaa acagccacag aaaaacgtat
    17221 ctggatgatc caagctcatt tgggcaaagc gccagagatc gacgcgtaaa aactgttgtt
    17281 gaacttgacc gaaaaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa
    17341 acgtcaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
    17401 tgaacaccgt ttaccaagag gttgtaagcc tgccgttcag ctccgagtca caagaaacaa
    17461 ttttaaaaaa cagcttctta tgttttatgg atattgtgac ttgtgaccga ggagttggca
    17521 ggagaacacc gtttattcaa aataaggggt tgtgacaaga cttttgtcac agcctctttt
    17581 tgtttttcat tttgacagga aacgaccctt ttatataaaa gaaagaaaag aagtaaagtt
    17641 tcatataaat ttttcaatca agcagaaaaa cgttgacatt gactagatta gcgggtaata
    17701 tgttaaatgg tattgtttgc cccacaaaga gccccggaaa ctcgaagtgt atgtcaaaca
    17761 tcagaactta aattggagga aaataacgtg cgtacaacat atatggccaa accaggcgaa
    17821 gtagaacgta aatggtatgt agtagacgca actgatgttc cattgggacg tctttcaaca
    17881 gttgttgcat ctgtactacg tggtaaaaat aaaccaactt tcacacctca tttggatact
    17941 ggcgatttcg tcatcgtcat caatgcagac aaagtgaaat taacaggtaa aaaagcgact
    18001 gacaaaattt attaccgtca cagcaactac ccaggaggat tgaaatcaat cactgctggc
    18061 gaattgcgtg ctaaaaattc tcgtcgtttg atcgaaactt ctgtaaaagg tatgcttcct
    18121 aaaaacactt taggccgcaa acaatttaca aaattgaacg tatacggtgg agcagaacat
    18181 ccacatgcag cacaacaacc agaagtttta gacatcacaa acttaatcta ataggaggga
    18241 atttcattgg cacaagttca atatatcggc acaggccgtc gtaaaaacgc agttgctcgc
    18301 gtacgtctag taccaggaac tggcaaaatt actgtaaata aaaaagatgt tgaagaatac
    18361 attccacatg ctgacttgcg tgaagtaatc aatcaacctt tcgctgttac tgaaacaaaa
    18421 ggcgcatatg acgtatttgt taacgtaaac ggcggaggat acgctggaca atcaggagct
    18481 atccgtcatg gtatcgctcg tgcattgcta gaagttgatc ctgacttccg tttagctctt
    18541 aaacgtgctg gcttacttac tcgtgacgca cgtatggtcg aacgtaaaaa accaggtctt
    18601 aagaaagcac gtaaagcttc acaattctca aaacgttaat atcctttata tatcaacgtt
    18661 tctggcactt ttcaattatt tggaaagtgc ttcttttgtt tttaagaaca catttaagaa
    18721 cacatatcaa tcacacttat tcaatcctct ctgaaaagct tcaaaaacag ccttatcaac
    18781 tatatctggt gtgttcacat atatctttgt tgtagaaata tctgagtgtg ttaaagcatt
    18841 tgaaatttga ttcatatctg ctccaccttg tctagctata gttgcataag tatgacggag
    18901 tttgtgtgga gataaatgaa ctaagtcagg atgccttctt ttaattgaat tgattcgata
    18961 gtttaggtaa tcggcatgaa caggacaatt tacttctcca gatggtttag tataagtaaa
    19021 gagatactga tctaacgttt gcttaatttt taatttcaac aattgatcag cttgtaccga
    19081 tttccattca cttagcaatg tcattacaac ttctggtact tgaatgacgg tatcttttcg
    19141 accttttgta aacttttttc tttgatattt atctaaagta tgtttaagac ggaccgttt
//
LOCUS       DADVXK010000049        19085 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.049, whole genome shotgun sequence.
ACCESSION   DADVXK010000049 DADVXK010000000
VERSION     DADVXK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.049"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(387..1853)
                     /locus_tag="KB909_001613"
     CDS             complement(387..1853)
                     /locus_tag="KB909_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6837636.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="KB909_001614"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="KB909_001614"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6837637.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4753..5112)
                     /locus_tag="KB909_001615"
     CDS             complement(4753..5112)
                     /locus_tag="KB909_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBB6837638.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="KB909_001616"
     CDS             complement(5142..5483)
                     /locus_tag="KB909_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837639.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="KB909_001617"
     CDS             complement(5480..6154)
                     /locus_tag="KB909_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6837640.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="KB909_001618"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="KB909_001618"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBB6837641.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="KB909_001619"
     CDS             complement(8668..9858)
                     /locus_tag="KB909_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6837642.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="KB909_001620"
     CDS             complement(9879..10406)
                     /locus_tag="KB909_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBB6837643.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="KB909_001621"
     CDS             complement(10453..13242)
                     /locus_tag="KB909_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6837644.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="KB909_001622"
     CDS             complement(13389..13589)
                     /locus_tag="KB909_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6837645.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="KB909_001623"
     CDS             complement(14042..14362)
                     /locus_tag="KB909_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837646.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="KB909_001624"
     CDS             complement(14865..15983)
                     /locus_tag="KB909_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837647.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16454..17761
                     /locus_tag="KB909_001625"
     CDS             16454..17761
                     /locus_tag="KB909_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBB6837648.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="KB909_001626"
     CDS             17882..19081
                     /locus_tag="KB909_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6837649.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
BASE COUNT         5469 a         4026 c         3323 g         6267 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaa
//
LOCUS       DADVXK010000050        18877 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.050, whole genome shotgun sequence.
ACCESSION   DADVXK010000050 DADVXK010000000
VERSION     DADVXK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.050"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(79..1128)
                     /gene="recA"
                     /locus_tag="KB909_001627"
     CDS             complement(79..1128)
                     /gene="recA"
                     /locus_tag="KB909_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBB6837650.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(1237..2478)
                     /locus_tag="KB909_001628"
     CDS             complement(1237..2478)
                     /locus_tag="KB909_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBB6837651.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(2718..3296)
                     /gene="pgsA"
                     /locus_tag="KB909_001629"
     CDS             complement(2718..3296)
                     /gene="pgsA"
                     /locus_tag="KB909_001629"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBB6837652.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(3505..4428)
                     /locus_tag="KB909_001630"
     CDS             complement(3505..4428)
                     /locus_tag="KB909_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837653.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(5167..6453)
                     /locus_tag="KB909_001631"
     CDS             complement(5167..6453)
                     /locus_tag="KB909_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6837654.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(6446..7714)
                     /locus_tag="KB909_001632"
     CDS             complement(6446..7714)
                     /locus_tag="KB909_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6837655.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            7966..8427
                     /gene="mscL"
                     /locus_tag="KB909_001633"
     CDS             7966..8427
                     /gene="mscL"
                     /locus_tag="KB909_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBB6837656.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(8486..8932)
                     /locus_tag="KB909_001634"
     CDS             complement(8486..8932)
                     /locus_tag="KB909_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837657.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(9025..9270)
                     /locus_tag="KB909_001635"
     CDS             complement(9025..9270)
                     /locus_tag="KB909_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBB6837658.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(9385..9963)
                     /locus_tag="KB909_001636"
     CDS             complement(9385..9963)
                     /locus_tag="KB909_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6837659.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(10040..10570)
                     /locus_tag="KB909_001637"
     CDS             complement(10040..10570)
                     /locus_tag="KB909_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBB6837660.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(10574..11434)
                     /gene="rlmB"
                     /locus_tag="KB909_001638"
     CDS             complement(10574..11434)
                     /gene="rlmB"
                     /locus_tag="KB909_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBB6837661.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(11427..11822)
                     /locus_tag="KB909_001639"
     CDS             complement(11427..11822)
                     /locus_tag="KB909_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBB6837662.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(11819..13231)
                     /locus_tag="KB909_001640"
     CDS             complement(11819..13231)
                     /locus_tag="KB909_001640"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBB6837663.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(13228..13764)
                     /gene="cysE"
                     /locus_tag="KB909_001641"
     CDS             complement(13228..13764)
                     /gene="cysE"
                     /locus_tag="KB909_001641"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBB6837664.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(13850..14089)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14086..15546)
                     /locus_tag="KB909_001642"
     CDS             complement(14086..15546)
                     /locus_tag="KB909_001642"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBB6837665.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(15716..16873)
                     /locus_tag="KB909_001643"
     CDS             complement(15716..16873)
                     /locus_tag="KB909_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBB6837666.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(16907..18277)
                     /gene="radA"
                     /locus_tag="KB909_001644"
     CDS             complement(16907..18277)
                     /gene="radA"
                     /locus_tag="KB909_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBB6837667.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(18340..18867)
                     /locus_tag="KB909_001645"
     CDS             complement(18340..18867)
                     /locus_tag="KB909_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBB6837668.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         4986 a         4166 c         3389 g         6336 t
ORIGIN      
        1 ttctttattc aataaaaaaa cggcaggtca aggagagtac ctactcttca gaccagccgt
       61 ttttgtttat cataattttt attcttctac taaaggcaat tcttcttgtc ctttttcatc
      121 ttctgggaca gcgacttctt caccaatacc ataagctgct ctaactagag cagaaacttc
      181 tgccatcatt tcaggatgat tagccatata gattttagcg ttttcccgtc cttgaccaat
      241 ccgatcttct ttataagaat accaagcacc gcttttatca acaatgtctt tttctactgc
      301 catgtctaga agttctcctt cttgtgagat ccctaaacca tacatgacat ctacttcagc
      361 gattttgaaa ggaggtgcta ctttgttttt tacgactttg atctttgtac ggttaccaac
      421 aatatctgta ccttgtttca attgttctgc acgacgtact tccaaacgga tcgttgcgta
      481 gaatttcaat gcgcgtcctc caggagtgat ttctggattc ccaaacatca cgcctacttt
      541 ttcacggatt tggttgatga aaatagcgat tgtttttgtt ttgttgatcg aaccagagag
      601 tttacgcaat gcttgagaca tcaaacgtgc ttgtaacccg acatgtgagt cacccatttc
      661 gccgtcgatt tctgctcgtg gaactaaagc agcaactgaa tcgactacta cgatatctac
      721 agccccactt gatactaaag catcagcgat ctctagacct tgttctcctg tgtcaggctg
      781 tgaaagaagt agttcatcga tattcacacc taatttttgt gcatattgcg gatctaacgc
      841 atgctcagca tcaatgaaag cggccgttcc gccatttttt tgtacttctg caatagcgtg
      901 tagtgcaact gttgttttac ctgaactttc aggtccatat acttcgatga tacgtccacg
      961 ggggtaaccg ccgacaccta aagcgacatc taacgcaaga gagccacttg gaattgtaga
     1021 gatttgttgg tcgatttttt cgcccaattt cataatagag cctttaccat agctcttttc
     1081 aatttttttc agtgcagcat ctaaggctgc tttacgatca tctgccaata cgataatcct
     1141 ccttatattt acaaatcaga gcaacatttc attatcctta tcatatcttt tttagtgaaa
     1201 aaaagcaaga aaaaaccgaa caaatattcg catttatcat tttcttaaaa gctgttttct
     1261 caaaagatca aatccttgca taaccgcatt atatctgata gcagcacgat ctctggcaaa
     1321 gtgatatttt tccgaaacca cgccgtcttt agatgaaata gcgatccata ctgttcctgc
     1381 agattgacct tctaacgtgt ccggtccagc cactccggtg aaagctacac tgtaatctgt
     1441 tcttgctatc tcacgtgctt gaatggccat ctgctccaca cattctttgc tgactgttcc
     1501 atattctgct aatagctccg gatcaatctc cagaaaacca gcttttgttt ggagcgagta
     1561 ggtaacgaat ccgcctggaa atacttcaga tacaccagca atgtcgccta atgcggcttg
     1621 gaaggcgccg gctgtcaaac tttccgctgc tgttacagtc tgcttgtttt ctttcagtag
     1681 ttccactacg acttttgcta gcgaattatc atcgccgtat ccataaaaat attcccctac
     1741 tcgttcttgg attttttctt ctaatgctaa aagagcttga ttccctgcct gaacatcatt
     1801 tgttttcact gtcagtcgta atgtcacttc atttggtttg gcatatggtg cgatcgttgg
     1861 attgatctgt gtctcaatca gatcttttag ctcagtgacc agtcgcgatt caccaatccc
     1921 ataaaagcgc aaaactttag aaattagttt ttcttcagaa ggaaaacgtt cctctagtaa
     1981 aggacgtact tgttccacaa acattggttt caactcatta ggcggaccgg gaagaaggat
     2041 atacgcatgt gtatctgttt gataaaaagt ccctaaagca agccctgtac gatttggtag
     2101 aggaaccccg ccttcgataa tctgggactg ttgcagattg tttttggtca tttttcgatg
     2161 ggttgtttca aaatatgcca ataatttttt gtatccttcc gtattttgta tgagagactt
     2221 accgaggtga gccgcagttg cttcttttgt caggtcatct tctgtcggtc ctaatccgcc
     2281 acataagagt atgagttcac ttcttgtttc agctagagca atcaactctt ctaaacgctg
     2341 ctgattatct cctacaactg tttgataata aacttcgata cctagatcag ctagctgttc
     2401 tgacaagaaa gtggcattcg tattcacgac ttgtcctagt aaaagttctg ttccgacagc
     2461 tattatttct gctttcatta cttcccgctc ccttatatag tatacgctgt atttttatat
     2521 ttttttattt aaaaagaggg caaggagctg tgacaaaaat cttgtcacag ctccttgttc
     2581 caaataaaca gtgttctcct gccaaaacct cggtcataag tcacaatata cataaaacat
     2641 gaaaagctgt tttttgaaat tatcccttgt gactcagagt tagacggcag gctcacaacc
     2701 tctccactaa acgatactta cattgatcct ttgaacacac cgctgttttt gatgaagtaa
     2761 tccacacctg aatagatagt aaagatcaga caagcataaa gcatgatttg atctactgga
     2821 ataccgatca ggctgaatgg gatattattg ataaacagca agataatagc aaccatttgt
     2881 gtagccgtct tgacttttcc cggccaagct gcagccatga cttctccatg ttcgacaagt
     2941 agtaaacgca agcctgtgac ggctaattca cgacagacaa tgatcgctac tacccaacca
     3001 ggggcctttc cttggtcaac caacatgata aaagcagtca taactagcat tttatctgcc
     3061 aacgggtccg caaacttgcc aaaattagtg acaaggcctc gcgcacgggc aatttttcca
     3121 tctaaccagt ctgtgatact agctaaagca aaaataactg cacctactag ctgtgtgaca
     3181 gccagtgtgg tgtctcctac gttaaattgt ccccaatcta aaggtaaacc tacaaccaaa
     3241 atgaaaatcg ggatcataca aattctaagt acagttaatt tatttggtaa attcacacta
     3301 tcgactcctt tcttccctat tctacgtgac tatcagcgaa gtttccaccg atattattta
     3361 cttttccaaa tgaatttatt caaaggagta tttttattga aattgatctt tttgaattaa
     3421 cgaagaagga ccgcgacaca gatttgtcac gatccttctt ttttatacct acaagtaaac
     3481 agatgcgtaa actaatttat acgatcattc tgcgtattga agagtaaggt tcacattttt
     3541 tggactctga ttgttttccc ctggattaac tggtacggat tctccattcg ctttgatcgt
     3601 tgcattgctt gctgcaccaa tcgtgatggt cgcatttgtt gctgtttccg gtaacacggt
     3661 actctgtgtt tcatttgctg ccagtgtccc ttgataaaca taggcattgt ctactagcac
     3721 acctaaccat acacgattga cagcagtaaa ttcaagggtt acaggcttgg tagcgtctgt
     3781 gatatttact gcgatggcac tgccagaatc ttctcctgta gctattgcca ttttcttttc
     3841 ttcacttgat tttgttgttg attctactgt agaagactct ttggtctgcg tgctttgctc
     3901 tgaggaagag gactcctcga ctgatccttc tactttaagc gaagaagctg tgtctccgat
     3961 tattggatca gcttgacgat cttgccaagt catatagccc acgacaacga caatcgccaa
     4021 agcaaccaat cctaataaaa tgacaggaag acttgtccaa aagcgacttg gatgcgattc
     4081 ttcctgatgc attgcttttc tagaagtact tactgtttca ggctgcggac gttcagggac
     4141 cgatcctgtc aatttgcttt tcccatcaaa aacatcgact aaatggtctc catcttctcc
     4201 tacagcttca gcgtattgcc gaataaatgc ccgcacgtaa aatttaccag gcaattggtc
     4261 aaaatcatca ttgtcgattg cttccaaata acgtttttga atttttgtaa tctgctgtaa
     4321 ttcatctaaa gatatttttt tattcaggcg tgcttgccgt aatttttctc cgatggtttc
     4381 aaaagccact cgttcatctt ctccagtctg tttgattctc cgaagcatct gctgttgcaa
     4441 cgaaagacgt tatgtttggg tgctgtgaca aaagtcatgt cacagctcct tttttccgaa
     4501 taaacattgt tctcctgcca actcctcggt cacaagtcac aatatccaat aaatataaga
     4561 agctgttttt tgaacttgtt ccttgtgact cggagttaaa cggcaggctc acgacctctt
     4621 tcttaaacgg tgttcaatca gctgttcctc ggtattagct caaaaaccgg caaaatataa
     4681 ggagatattt ttccgtatgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
     4741 ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agtccaacca agttaaaaac
     4801 attaagaagc tgtttttact tggctgttct tattacttga tgcagggcag ctttttcaca
     4861 acctcttggt acacggtgtt ccagaagtag cttcttcggc aataagccga aatatcacaa
     4921 aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctgtc
     4981 acaacctctt tgattacttc gtttgatttt attttaatat aagttgatta aaagagagca
     5041 tgatttgttt tattttctca ctaatttttc caacacaact aagaatacca taaaagctga
     5101 ttttggagga ggttcctact acaagtctaa aacgaaattt aagacttttc ctcataaaat
     5161 actggtttat tttggtctca tgtaaaactc gctgaaggcc tcttcactta taaatgcttc
     5221 cccagctgcc agtacgtctt tcatttggat cgaatcgatg atttcaggaa gatcaaataa
     5281 agttcgatcg ccaaataaac tttgcgtaaa ttgattggca atatattcga tcgaatttaa
     5341 tgattggaaa tattgtccaa gcattttctt cttcagcaaa tcgagatttg tttctgacac
     5401 ttccggatca tcagcgaatc caagaatgat ttctttgact ttttctgctg ctttctctgg
     5461 ttcgtccgta tctccgctga agtccgcaaa gtgaaattca cgatccaagc tgaattcaaa
     5521 accaaagctg tcatcgataa ttccttgatt gtacatcgct agatagtttc gagaagtatt
     5581 gcctaaaatc atttggaaca acagattgat tgctgtttta tagcgtaaca gttctgttcc
     5641 ttcttgcggc aatgtgtcta atcctttaat accaagtaca aatttatctc gtgtaatggc
     5701 tgcttccaat gcactttgtt tgatgatttc ttttgtgttt tcagggaaat aacgtacaat
     5761 ttcttgcttt ggagggaaat tttttgcttc ttggttttcc cgaataagtt tcatcaattt
     5821 ctcaggctcc atcttaccaa ctacaaataa aaccatattg cttggctgat aaaacgtccg
     5881 atagcacgta tacaagtctt gagctgtgat tttgtcgata ctttcaaccg tgcccgcaat
     5941 atcgatatgc aatgggtgtg taggatacaa gttatttagt atgccaaaaa acatccgcca
     6001 gttagggtcg tcttcataca tttggatttc ctgaccgatg attccttttt ccttgtttac
     6061 agtttcttct gtgaagtaag gtgcttgtac aaaatcgatc agagtcgtca gattcttttc
     6121 tacctgatcc gtcgtagaaa acagatagct ggttttcgta aaacttgtga aagcattggc
     6181 ggaagctcct tgtttcccaa ataattgaaa gacatcacca tcttcttttt caaacaactt
     6241 atgttctaaa aaatgggcaa ttccatctgg aactttcacc ttttcttttt caccataggg
     6301 aataaattcg ttatcgatcg aaccataatt cgtactgaac aaaccatatg tcttgtgata
     6361 gtcattttta ggcaacaaat acacggtcaa accgtttggc agtacttcat gataaagtgt
     6421 ttcattgatt tgctcatatt ctgttttatt catttgcatt tcctcctgct aaaaagaaga
     6481 ttgcctgcaa ttcgatttgc tcagctactt gttgtatctc tttgatcgtt acgctctcca
     6541 tacgtttcaa ccattcttca tcagataatt ttgtttccgg cagccagctg tccaaaaaag
     6601 aagcttcgat tgccgcttgc ggagagtcta gagaaagcag atattggttt ctcagcattg
     6661 cttttgtctg agacagttcc aactctgtta tttcaccatt tcgcaaactt tctaattgct
     6721 cgtgaatcag atgaagtact tgatttcggt tcttttcatc gataccggtt tggacactca
     6781 tgaatcctcg gaacgtatcc acgctactag aggcataata agctagactt tctttctctc
     6841 tgacattcat gaaaagttta gagtgaggaa aaccgccaaa taaaccgtta aagaccatta
     6901 gcgcaaaacg ttctggttca tcgtaataca catttgtctg ataagctagg ttcagctttg
     6961 cttgaacgat tggctcacgt acttgtcgtt ccttcacgat attcacttga ggttgggtat
     7021 aaaacagatc tggataaact gtttcccgcg actcaaatgg taattgccca actgcttcag
     7081 ctgctttgtc cggatcaaca tcgccgacaa caaaaatgtc gatttgatca tttgccatca
     7141 tttcttgata gtaggacgct agcgaactag cagtgatctt gtccaaatct tcgactacgc
     7201 ccaaccctgg gatcttttgt tccgggctgt tttcaaaata aagttcttgc aaggcatagg
     7261 aagcaaaagt ttgtttatct tccttcaaac tttccaaata tagacgcaga ttgttctttt
     7321 ccaagtcaaa cgtcaactga tcaaactgat gatttttaat atttggataa aataaaacct
     7381 cttttaaaaa atctaccgct tgagaaaaaa ggtttggatc attgacatat tcaccattca
     7441 caaaactgat ccctgcgttt agccaatgta aatttccttt ttttctaact gataatccaa
     7501 agcttgcgcc ataaagctct gcaagttgcg cacttaactt tgtctgatcc gaataattca
     7561 aactatttgt ttccaacatg ctgctgagaa gtgaacgttt cgtgatgact tcttgttgca
     7621 gacgcgcagt aaaacggata aaaatccgga tcgttttgta ttgttttgtt ggtaagacat
     7681 gaagattcac gccttctgcc aattgataca ccatatttat atgctccttt tcacagttga
     7741 ttgcccgctt actcttttaa tgggtcaacc tgcctttttt acttattcct ctgcttgaaa
     7801 tttataagtt caggcaattc gccgtttttt ctaaatgatg ttacacttta tagtatagca
     7861 tagatgtttt ttatcaaaag aaacagacgg ctaaaagcgt atattgtttt tttatttttt
     7921 atttttcgat atactaaaga caaataaaag aagggagggt cattcatgat caaagaattc
     7981 aaagagttca tcatgcgtgg agatgtcttg gatcttgctg tcggcgttgt tattggtagt
     8041 gcgtttacaa gcatcgtaaa ccaagtggtg caaggcttga tcacaccact aataggttgg
     8101 tttgtcgcaa tgatcacagg tacttctgat ttagaaggag cactttcaat tcttgactgg
     8161 tcgccgacaa aaggcgtcac atttgcgttt ggtaacgtta ttagtgctat cattacattt
     8221 ctgatcactg gttttgtctt attcttagtt gtcaaagcgg caaaccgtgc gaagaattta
     8281 cgctccaaag aagagcaagt ggaagtggaa gaaactccta ctgcagaaga ttatcttagt
     8341 gacatacgcg atcttcttgc caaacaagtg gcagaagaca atacacatcc agtagagcaa
     8401 acaaatcttt ccgatacttc taaataataa agaatctaaa aaaaagaaag ccgattttca
     8461 gtgtcggctt tcttttttta gattcttaac ttgctacttg ttcctttttc atgtcgatat
     8521 gtggaatatc atcttccaaa tacacatctg agattgcctt gaatccaaac gactcataaa
     8581 aagcttgtag gtattcttgt gcgccgatca cgattggttt ttctggaaaa tttttctgga
     8641 tcatgttaat cgtttcttga acaatctttc ttcctaaacc atctttacgg ttgtcctgat
     8701 gaacaaggac acgtccaaaa tggatactct ccgcttcttc atatactcgc gtgtaggcaa
     8761 ggatcttccc atcagtatct tgaaaaaacg tatgccaagc ttctccatca atgtcatcaa
     8821 cttcttgata aggacactgt tgttccacaa caaaaactgc gattcgttct ttgacgatcg
     8881 cgtaaaactc tgctgttgac aattcttcaa atttctttac ctgatattcc actaagcaaa
     8941 cgccccctgc ttttttattc ttagcatacc gattcgcaca caaaaaagca aacgaacctt
     9001 acgaatctca ggctcgtttg ctttttaaac tgcttcagtt aaaaattcga tctcaactgt
     9061 ccgagtaagt acatctgaat agctgtaaga tactcgttca aaagaatttt cttcaggatc
     9121 caaatcaaca acgaatactg aaggataggt ttctgttaaa acgccgcggc gttctgtttg
     9181 acgctttctt cctgtctgag caaccaacat gattgggctg ccgatacgac cttctaaatc
     9241 tttcttgatt gaagctaaag ttgttggcat acagttcacc tctactatca actataccac
     9301 atatttttaa aattttcaag tttaccataa aaaaaaaaga aatgcaataa aaataaataa
     9361 gaagctcatt aagatttttc taaattattc ctcattataa aatttcaagt gtttttttat
     9421 tttgagtttt actctcccgt aagcgctcat tacttgcttg tgatccattg ctaaacattc
     9481 agccatgtct acaaaatcaa cgccttgcat ataataatga aaaattttag cttctatttt
     9541 tgaaaactgg atttcgcaat tttcgattgc ttcttttaat aaaagatgct gaattgctaa
     9601 aggttcttgc aatgtgatct ctgctaaaaa gtctggtcct tctgtctcta ttttttggtc
     9661 gattgagact tcatcttttt gatcacgacg cttcagcgcg ttctgcttcc tcaacagaga
     9721 atagatttga ttgcttataa cgcttttata ataacttcca aagctaacac ctttgctttt
     9781 ttcgtaagtt ctcaatgcct gatataaagc gatccttgct tcttgttccc aatcctcaga
     9841 aacataattt cttaaataat aggtgttttt caaacgtagt aaaagtggaa aatatttttg
     9901 atacagggca gcaaatgctt cttcgtcacc attacgtgca gcgcgcaata actcctcaga
     9961 cataaaataa ttcctccata aattcgttta tggaggaatc ttatcatcaa tgattcatcg
    10021 aactgattag aacgatatgt tatttatttt ttctcattaa atcgtccaat ttttgggaca
    10081 atttttttaa ctgctcttca ttccatggag aattacgtcg gaaatcaata aaatgcatat
    10141 ctttattttc ttgggctatt gttttttccg ttttttttat cgtcttatat aattcataag
    10201 cagaagttcg taatgctcct tgggaaaaga tcatccactg ttctgctaaa tcgcttgtcg
    10261 ccactgtcac ttgtgtcaaa cggtcattca gctgaccagc gattctctcg atataactgt
    10321 cagccgtttc gtcttctttc gtaaaaacaa catccaactg gtatttctta taattttgtt
    10381 ggatgcccgg aactagttgg gcatcgaaga caacgatgac ttccattcct tcatatttcg
    10441 cataatttga taaacgatgt aaaagagctt ctcttgcatc cgccattttg tcctgctttt
    10501 taagctggac aagttccggc cacgaaccaa tcatgttgta gccgtctaca atcaacagct
    10561 gttttttcat ggtctactcc ccctgacgtt gggaaaaagc ctgatacata agcaaaccag
    10621 cagcaacact ggcatttaag ctctggacgt gcccggtcat cgggatcgtc agcaattcat
    10681 ccatttcttt tttcaatcct ggactcattc ctttgccttc attaccaatg actaaagcaa
    10741 ttgatccttt ggcattccat ttttggaagt ttgtgccggt catatctgtg ccaaataccc
    10801 aaaatcctgt ttctttgagc tgttgcacag cttgtaccaa attcgtcacg cgtgcaacag
    10861 ggacatgttc gactgcccca gtggaagtct ttgttacgat aggtgtgatt ccaactgctc
    10921 ggtgttttgg tatgatcaca ccatcgacgc cacttgcgtc tgctgtccgt aaaatcgacc
    10981 caaaattgtg tggatcttcg atgctatcca aaatcaaaaa gaaggggtct tcttttttct
    11041 cttttgttcg ttcaatcagt tggtcaaggg ataaatattc ataaggtgta atcgcaagaa
    11101 cgactccttg atgcacgccg tgatcgctca aagtttctaa tttttgttta ggaacccatt
    11161 tgactggcac agcttgttca cgtgcgattt ctttcagttc ttctactttt tctcctcgtg
    11221 aatcttcttg aagaaagagt ttattccctc gcccttgttg tagcgcttct actgcggcat
    11281 ggtgcccaaa gacgaaatta tcttctaatg cttcttcatt ttgatcagaa actgactgat
    11341 ttcgtccagt ttgcttttta tttgaatatc tattttgttt tttgtcttca aatccacgtt
    11401 tcgattgatg tttgtttgtt ctttctttac ccattttttt caccaacttt ctgaatacac
    11461 cagcggatca attcttccat ccgctcggtt tgttttgtca aatgcagata gcccatgagc
    11521 gcttcgaacc ctgttgcgac ccgatacgtc gtaacatcag cattttttgc gctcgtatgg
    11581 cttttagcat ttcttcctct gcgataataa agttcttctt cttctgtcaa aagatgttct
    11641 tccagcattt gctgaatcaa aaaggcttgt gcattcgcag aaacataatt cgttgccgca
    11701 cgatgcagct tattgggttt tgtttctcct tgatcaatca ggtggtcacg aacatagatt
    11761 tcgtaaatcg catctccaac ataagccaag gctaaaccgt tcaattgtgt gtaatctctc
    11821 atgcttctct tctccatcgg gttccttgcg gtgtatcttc taataagatc cctttttctt
    11881 tcaacaaatc acgaatttcg tcgcttcgga caaaatcacg attgcttctt gcttgatttc
    11941 gttcttcgat caattgttca atctcttcat ctaataactc ttctgctgta aataaaatac
    12001 cgaagatcga aagccattgc gagaataaag cttctccttg tgccaagaca gcggcagaaa
    12061 ctttcggctg gtctagataa gtgttcagcc acttagcaag ctcatagacc actgtgatcc
    12121 catttgctgc attaaaatca tcgtccattt cttcgatgaa tcgctgttct aaattttcta
    12181 acaaagcgat tttatccgca tcatctgcca aattctctga ggcagtttct tggcggaatt
    12241 tcaaattgtc aaacgtattc ttcagtcgtt gtaaattggt ggctgcttct ttcatcgtcg
    12301 tttcactgta gcggatcgga cgacggtatt gtgtggtcgc catgaagaaa cgcaagactt
    12361 gtggatcaac gtttttgatc atttcatgta cagtgatgaa attccctaga gatttactca
    12421 ttttttcatc gtcttcgcca atcgttacat agccattgtg catccagtaa ttagcgaatt
    12481 ttttccctgt tttcgcttca ctttgtgcga tttcattttc atgatgagga aattctaaat
    12541 cttgcccgcc accatggata tcgatcgttt ctcctaaatg ttttgttgcc ataacggaac
    12601 attcaatatg ccaaccggga cgtcctttgc cccatggtga atcccaagaa atctcgccag
    12661 gttttgcttg tttccataaa gcgaaatcta atgggtcttc tttttgctgc tgttcttccc
    12721 ctgtacgctg acttgctccg acttccagtt catcgatgga ttggtcactt aatttcccat
    12781 aattttcaaa tttacgggta cggtaataca catcacctga agattcataa gcatagcctt
    12841 tttcaaccaa cacttgaata aatgctaaaa tatctggcat atgatccatg actcttggat
    12901 gcagtgtagc aggttcgaca ttcaacgctt tcgtatcttc ttcaaatgct cggatgaaac
    12961 gatcagcaac ttctggtgct gtaataccta attcgtttgc tgtacggatg attttatcgt
    13021 ctacatccgt gaaattcgat acgaaatcga ctttatagcc tcgatattca aaatagcgtc
    13081 gaattgtatc gaaagcaatg gtgctacgag catttccgat atggatataa ttatacacag
    13141 tcggtccgca gacatacata ccgacatgtc ccttttgtat agggatgaat tcttcttttt
    13201 ttctggtcaa tgtattgtag atttttatca ttctgatctc ctcacttttt ctcctttgat
    13261 tcgaacgact tttgctggta ctcctaccgc tgtagcgtcg tctggaacat ctttcaacac
    13321 aacggcacct gcaccgattt tggcgttttt tccgatcgtt accggtccta atatctgcgc
    13381 attcgcagag agcatggctc cttgtttaac agttgggtgt cttttacccg tttcttttcc
    13441 tgtgccgcct aatgttacgc catggaataa aatcacatcg tcctcgattt ctgcggtttc
    13501 gccaatgacg attcccattc catggtcgat gaacacgcca gttccaatcg ttgctcctgg
    13561 atggatctca acaccagtta ggaaacgcca gaattgagca ttgatcttcg ccaataaaaa
    13621 gagccggtgc tgatataaaa aatgagagaa acgatgccaa aacaaggcat gaaaaccagg
    13681 gtatgtcaaa acgatctcag ctgtcgaacg tgcagccgga tcgtttctct ttgctgcatc
    13741 aatcgctcgg gtaaaccaac tcatgacttt ccactccttt cgtaagaatt ttatgtagga
    13801 aatcatcttc ttataaagaa aagaagcgcc ttttaaataa gtttccttat caaaagacgc
    13861 tttccgcgtg gttccacttt tcttcataat caatgattat ctctgacagc taacgcctgt
    13921 tatacgttct tggctacttt gtttcctata aaacagtttt tcctgttttc tgtgtttcgc
    13981 caagaccact cccagaggca tttcggcaac cattcattga taccttgcac cacccggtat
    14041 ctctcttgta atgatcagct gcttactttt ttctgttcat cgtgtttagt tcagtacttg
    14101 atttaaatgt gctaatgatt tttcacgacc aagcaattcg atcgtttcag gcaattctgg
    14161 accatgcatt tgtcctgata cagctacacg gattggcatg aaaagatttt ttccttttac
    14221 gccagtttct ttttgaacag ctttgatggc agctttgaca gttggagcat ctactacttc
    14281 catttgttct agctgtgctt tgaatgcgtg gagaacagta ggaactgttt caccagcaag
    14341 tacttctttt gctgcttcat tcaatacagg atgttcattg aaaaatagcg tagacagatc
    14401 aacgatttct gcagcatagc tcatttgagg ttgatacagg ctaacgatct tcttcaccca
    14461 ttcgattgtc ttttcatctg ggttttctgc tacacgtcca tcagcgatta gataaggcag
    14521 acacatgtca gtaaatgcat ctagatccat tgctttgatg taatggttgt ttacccattg
    14581 cagttttttc gcatcgaaag ctgcgggtga tttacttagg cgttttggat cgaacatttt
    14641 gatcaattct tggtgttcga agatttcgtc ttcgcccaca ggtgaccagc ccaataatgc
    14701 aataaagttg aacattgcat ctggtagata gcctaattcg cgatattgtt cgataaattg
    14761 caagattgat tcgtcacgtt tgcttagttt tttacctgtt tcactgttga tgatcaatgt
    14821 catatgtccg aaggttggtg gtgtccagcc aaatgcttca tagatcatca gttgttttgg
    14881 tgtattggca atatggtcat ctccacgtaa aacgtgagtg attttcatca aatgatcatc
    14941 gaccgcaaca gcaaaattat aagttggcat accatcgcgt ttttggatga caaagtcgcc
    15001 accgatatta tcggattcga acgaaatagc gcctttcacc atatctgtaa atgcgtattc
    15061 tgtattgcga ggcacacgga aacgtacaac agattctaga ccttgtgctt ctttttctgc
    15121 ttgttcttca ggtgtcaagt tcgcacatgt tcctgcgtaa tgaggcattt ctcctcttgc
    15181 gcgttgtgct tcccgttctg cttctaattc ttcttctgtg caatagcatt tgtatgctcg
    15241 attgctagca agcagctgat caatcagcgg ttgatagatt tctttacgtt cagattgacg
    15301 gtaagggccg tattctccag gattttcagg agattcatcc caattcattc ccaaccaagc
    15361 aaggttttcc aactggcttt tttcgccatc ttcgatatta cgtttttggt cagtatcctc
    15421 aatacgaata ataaagtctc catcattgtg gcgggcaaac aaataattga ataatgcagt
    15481 tcttgcattt ccaatatgca ggtgcccagt tggacttggt gcatagcgta cgcgtacttt
    15541 cgtcattttc ttcctcttct ttcaaactag actttgacta acagcaaaaa ttccgtcagt
    15601 tacggcttct caaatatcat ttatttaaag ccactcagca caaattttac cttttctaag
    15661 gtaaatagta aagccaactg gttgaatttc cttaccagtt ggctgaattt cttttttatt
    15721 ttgattgttt agtctttttc tctgtctctt ttttattgtc gattcctcgt cctgcatgtg
    15781 caggtttagc aaagatcatg cgtccagcag ctgtttgaag ggcacttgtt acaacgactt
    15841 cgatacgttc attcatgtaa tgctgtccat cttctacgac aaccatcgtg ccgtcatcaa
    15901 ggtaggctac tccttgttgg cgttctgtcc cggcttttac tactagaaca ttcatcgttt
    15961 caccagggat gacgactggt tttacggcat ttgccaacgc attgatatta agaacaggta
    16021 cattttggaa ttcagagact ttattcaagt tatagtcatt ggttacaatg acaccatcta
    16081 aaagcttagc caatttgatc aatttgctgt ctacttcact gatatcttca aagtctccat
    16141 cgtacatttc gacagatata ccctcttctt tttgcaaggc atttaggata tctaatccgc
    16201 gacgaccacg cacacgtttc aaactatccc ctgagtccgc gatgtattgt agttcgtaaa
    16261 gaacaaaatt agggatcatc aaggttcctt ctaagaatcc agtctttgta atatcataaa
    16321 tccgaccgtc aatgatcacg cttgtatcca agattttata tttatggaaa ttttctcctg
    16381 attttcgttc taacagttga ctctcaactt gactagctgt ttcttgctcg atttttttgc
    16441 ttcgtgaacc aaaaactttc ttccattctt cgattcgtgt cgttcccatt ctcaatccca
    16501 gatagcctaa gatgatcatc agtaaaatcg gcaatacact attgacgaat ggaatttcca
    16561 tattgtaaag aggggtcgag atcacaacac ctaaagtcaa tccgatgatc gcaccgatcg
    16621 caccgaagag aagataagtc aagctgacct cacttagttt ttgttctact tgtttgataa
    16681 tagctgagat atgtttggcc aacagcaaag ataataaaaa gaaaataagt gcgcctaaca
    16741 ggctgttggt aaatgtatta ttcagccatc cgtttgactg ttgaccgatt gcctgccaag
    16801 ctgagggtaa aaatgaaata cccaagcttg cgccgacaat gatcatcagc aaagtaatga
    16861 cacgtttttg catcgttttt cctccgtttc gacaatcatt tattagttag cggaacacac
    16921 gcttcaacgt ttcagccaaa gttgctactc caactatctc gattcctttt ggcgcttccc
    16981 agttacctaa gttgttttta ggtaggtata cttttgtgaa gccgagtttt tggacttctt
    17041 tgactcgttg ttcaatatga ctgacacgtc tgatttctcc agtcagtcca atttcaccga
    17101 tgaaacattc cgttggctgt gttccttttt ctttatagct tgaagcaata ctgacagcga
    17161 tagctaaatc aatcgctggt tcatttaatt ttaccccacc tgcagctttt aagtaagcat
    17221 cttgattctg aagaagcaac ccagctcttt tttccagcac tgccatgatc agagataccc
    17281 gattgaaatc aagacctgtt gttgttcgtt tggcatttcc gaacatagta ggtgtgacta
    17341 atgcttggat ctctaccaaa attggacgtg tcccttccat tgccacaacg atagcagagc
    17401 cagttgcacc gtctaggcgt tcttctaaga aaatctgtga aggattagcg acttcttcca
    17461 atccatgctc atgcatttca aaaatcccaa tctcattcgt tgagccaaat cggtttttta
    17521 ctgctcgcaa aatccgaaaa ctatgatgtt gttcaccttc aaaatataac accgtatcca
    17581 ccatatgttc taacattctt gggccggcga tcgagccttc tttggtaaca tgaccgacga
    17641 taaaaatggc tatcccattt gttttagcgg ttttgagtag ttctgcagtg gtttctctta
    17701 cttggctgac acttcctgcc acacttgtga tgtctggctg cgtcatcgtt tggatggaat
    17761 caatgataac ataatcaggg gagatatgtt cgatggcacg actgatttcg ttcatatctg
    17821 tttcagcgta tagataaaat tctgtgttga tacttccgag gcgttccgcg cgtaatttta
    17881 tctgctctgc gctttcttcg ccggatacat ataagacttt tccgcctatg gctgctaatt
    17941 gctgagaaac ttgtaacagc aaagtggatt tcccgatacc tggatcgcca ccaatcaaga
    18001 ccatagaccc tggcaccaca cctccgccta acacacggtt cagttcttct aattttgttt
    18061 tgatccgagg ttctttttta gggacgacgt ctgcgatttt tgttggtttt gctttttctc
    18121 ctgtcaaact tgtccgagtt ctgcggtccg ttgtatcttg ttcgatttct tcgaccatcg
    18181 tattccattt tccgcaattt gggcagcgtc ccaagaactt aggcgacaca tacccgcaat
    18241 tttggcaaac aaattgtact tttgattttt ttgccattgt accgcctcct tttatcctaa
    18301 tcatgagaca ttaaatcaag cttaagtatc tttaacgttt tatttactgg aagaaccaaa
    18361 tccgccttga cgttgagcag tcgtttgatc ttgatctgct tttaaaaacg gcaaaaagat
    18421 cccttggccg atacgctcgc cttttttgat cactacatcc ttgaaaccaa agttggtgaa
    18481 ttggaacatg atatggcctt catttgcctc attattgtaa taatcactgt caatcacacc
    18541 tactccgttt gtcaacacta aaaaccgctt caacggattg cttgaacggt tagcaagctg
    18601 caaaaattca tcttctccca tgtaagcttt gattccagta ggcacgaggg ttggtttcaa
    18661 ttgtttttca ttttctgata catctttttt caatccatct gcgactgttt ccaacccctt
    18721 tttccagcct gctttccaga tacttggaat cacgacctct tctgctgctt caaaatcata
    18781 gccagcagca tgatgtgtag cgcgctgcgg tagattgata ttttgatctt tatatttaga
    18841 aataacttca aatcctcttt ttctcaccgg ttttcct
//
LOCUS       DADVXK010000051        18632 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.051, whole genome shotgun sequence.
ACCESSION   DADVXK010000051 DADVXK010000000
VERSION     DADVXK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.051"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(15..425)
                     /locus_tag="KB909_001646"
     CDS             complement(15..425)
                     /locus_tag="KB909_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6837669.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            700..912
                     /locus_tag="KB909_001647"
     CDS             700..912
                     /locus_tag="KB909_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6837670.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            915..1127
                     /locus_tag="KB909_001648"
     CDS             915..1127
                     /locus_tag="KB909_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837671.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1267..1422
                     /locus_tag="KB909_001649"
     CDS             1267..1422
                     /locus_tag="KB909_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837672.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(1419..1643)
                     /locus_tag="KB909_001650"
     CDS             complement(1419..1643)
                     /locus_tag="KB909_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6837673.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            1721..1909
                     /locus_tag="KB909_001651"
     CDS             1721..1909
                     /locus_tag="KB909_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837674.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2235..2570
                     /locus_tag="KB909_001652"
     CDS             2235..2570
                     /locus_tag="KB909_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837675.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            2803..3744
                     /locus_tag="KB909_001653"
     CDS             2803..3744
                     /locus_tag="KB909_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBB6837676.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            3746..4636
                     /locus_tag="KB909_001654"
     CDS             3746..4636
                     /locus_tag="KB909_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBB6837677.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            4679..5479
                     /locus_tag="KB909_001655"
     CDS             4679..5479
                     /locus_tag="KB909_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBB6837678.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            5494..6345
                     /locus_tag="KB909_001656"
     CDS             5494..6345
                     /locus_tag="KB909_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6837679.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            6546..7007
                     /locus_tag="KB909_001657"
     CDS             6546..7007
                     /locus_tag="KB909_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6837680.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7033..7485
                     /locus_tag="KB909_001658"
     CDS             7033..7485
                     /locus_tag="KB909_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837681.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            7591..7785
                     /locus_tag="KB909_001659"
     CDS             7591..7785
                     /locus_tag="KB909_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837682.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            7816..8202
                     /locus_tag="KB909_001660"
     CDS             7816..8202
                     /locus_tag="KB909_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837683.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8199..8402
                     /locus_tag="KB909_001661"
     CDS             8199..8402
                     /locus_tag="KB909_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6837684.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            8399..8695
                     /locus_tag="KB909_001662"
     CDS             8399..8695
                     /locus_tag="KB909_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837685.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            8771..9187
                     /locus_tag="KB909_001663"
     CDS             8771..9187
                     /locus_tag="KB909_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6837686.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            9448..9585
                     /locus_tag="KB909_001664"
     CDS             9448..9585
                     /locus_tag="KB909_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837687.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            9995..10225
                     /locus_tag="KB909_001665"
     CDS             9995..10225
                     /locus_tag="KB909_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837688.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            10384..11217
                     /locus_tag="KB909_001666"
     CDS             10384..11217
                     /locus_tag="KB909_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBB6837689.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11210..12625
                     /locus_tag="KB909_001667"
     CDS             11210..12625
                     /locus_tag="KB909_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBB6837690.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            12637..14166
                     /locus_tag="KB909_001668"
     CDS             12637..14166
                     /locus_tag="KB909_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6837691.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14084..15136
                     /locus_tag="KB909_001669"
     CDS             14084..15136
                     /locus_tag="KB909_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBB6837692.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15138..15455
                     /locus_tag="KB909_001670"
     CDS             15138..15455
                     /locus_tag="KB909_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837693.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            15582..16205
                     /locus_tag="KB909_001671"
     CDS             15582..16205
                     /locus_tag="KB909_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBB6837694.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16220..17110
                     /locus_tag="KB909_001672"
     CDS             16220..17110
                     /locus_tag="KB909_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBB6837695.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17133..17348
                     /locus_tag="KB909_001673"
     CDS             17133..17348
                     /locus_tag="KB909_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837696.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17360..17701
                     /locus_tag="KB909_001674"
     CDS             17360..17701
                     /locus_tag="KB909_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837697.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            17701..18072
                     /locus_tag="KB909_001675"
     CDS             17701..18072
                     /locus_tag="KB909_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837698.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18065..18460
                     /locus_tag="KB909_001676"
     CDS             18065..18460
                     /locus_tag="KB909_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBB6837699.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            18462..>18632
                     /locus_tag="KB909_001677"
     CDS             18462..>18632
                     /locus_tag="KB909_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837700.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSF"
BASE COUNT         6816 a         2758 c         3877 g         5181 t
ORIGIN      
        1 ataccaaagc ccacctattg acgatatttt ttaggagtga attttttctt tgctttaact
       61 ttggttaagg caagtgcaag ttgaatggca tcgtataatt tttccttatc ttcatcgtct
      121 aaaggttcac cataataatt tgtttcagca tctgaattca agccttcaag taatttttca
      181 gcttgtaaag caatatcttg tttatctttt tctgttaaat cataataatg gcgtttatca
      241 gtacgtccta aaagataatc agttgataca ttaaagtaat ctgcaacttt ttgtatttta
      301 tctccagatg gagtactttt attccatcta gacatgcttc catttccgaa atttaacttt
      361 ctttcaagtt ctgccaacgt cattgaacgt tcttttaata agatttttat acggtctaat
      421 agcataggat atgcattcct ttcaaaatac cgacaaaaaa agtatttttc tgcaaattat
      481 ctatttacaa atagagaatt tgcagttata ctagttttgt aagcaagata tttacggcat
      541 acaaagacta aaagcaataa actaatagtc tccccagaca tcagtaagct cgctttttgt
      601 gcgctgtatt ttgtatgctt acataatagc atatttgcag tttttgtcaa acttattaga
      661 caaaaatatt agaaaatatt cgataagggg gtatgaagca tgactttaaa acagcaagta
      721 ttaattgctt tagtaaagaa aggttggagt caaagagagt tagctcgacg aatgggtata
      781 tcaattactt atttacgaga tatcttcatc gaaaaaagaa aacctaagga acgtttaaaa
      841 caaatcgaag aacttttgga tatcaagtta gaagtagatt ctaatgatca gccatcagaa
      901 caggaggcgt aaaaatggta caacgtttga gcaaagcgga gtttaaagag aaatataagt
      961 attctgaaag tacttatcaa agaagaatga aggaatttaa aaaatcacgt tttagtgagg
     1021 ggtataacgc agttacttcc aaagaaataa caattgatgt cgatttatat gaacagttta
     1081 gaacatggcg ttctaaaaat cgatttagag ttagagctgt ttgttaatag ctaaaaaatc
     1141 taaattcacc acttctgaaa agaggagttg ctgctctcct ttcaagtttg ccaaagtcca
     1201 cgttttttca ttttggcaac tcctcttctt ggaggtggtg acggcgagag acgaaggagg
     1261 gatgacatga aggaagaatc aaaaataggg attttgaatg agaacaatta cacaagatta
     1321 attattgaaa cagaagaagg gaaaaaagta gcagaagtta cattgaccga tgcaactcct
     1381 gctgacggtt atcgtattcg attaactcct aaatatgatt aaccttttgg tgggtgtgga
     1441 tcgtttccgt gactatcacg gctttgaatt tttccatctc tgccatgaat aaatagctca
     1501 gatccttgat ttttagaaat ctctctagcg atttttactg cttctgattt tgtattagta
     1561 tgtgcagtcg ctttagaatt tccagcacct ttgacattcc aaccaccatt ggaattaggt
     1621 acaacatgtt gattttttcc catagttttc acctccattt ctatagaaat attttatcaa
     1681 atagaaatgg agaaattcaa taaacgaaag gagaagtgat atggcatata ccttgcaaca
     1741 agaacatcaa attctcggtt tgattaaaca acgcaggaaa caattacaag atgaccgtgc
     1801 agcgcttaga aaagccgatg agctatcaga taggcaagct gaactaattg cttctgaact
     1861 tgaggatttg agaatgctag aaataaaaaa tagggagatt agattatgaa gaagacagac
     1921 acacttttta taggattcat tttggggtta ttagtgattg tagcgcacca aagtattatc
     1981 gggggaagct tgttcgcagc attgatggtt ttaatcaatc tgcttgattc aaaagaaagg
     2041 agcaactatg gcacgagaag aagcgctaaa aatcggtaaa gtgattgctg ataatcggtg
     2101 gggaaatagc cgccctatta ttttaagcaa gcaacatatc gaaaagcaaa aagcatggca
     2161 acaaataaaa aagtgactct gccagccagc aaagagtcac atacaaattt ataaaactag
     2221 gagaattata tcacatgaat aagaaaattg aaaatcttat cgaagaattg aaacgtgaat
     2281 gccaaaagca aggtgtttct attatttgta cagcccaaaa agaaggggaa cttaaaagtc
     2341 tcgtttatgg tgagacaaca gaaattttac tttgtcttgc tatgcaagaa gaacatttag
     2401 atgaaaatct cccattgtca gcacatatta tgcgtagaat tgctgtggat gcttacgaac
     2461 aagcgaaaaa tgaagaagaa aatcaacctt caaatcatac ttttgttatt aataacaagg
     2521 aagatttagc tgatgtgatg actcgtattc tcaaggggga atttcaatga tgaatgaaaa
     2581 aacaattgat ctactcatta ttttattttt cacgttagtg attgtagcga aaagttatgt
     2641 aatctttggc ttgttattcg caattaccat gcttgtgctt tgcgtgttag caagcagaaa
     2701 agaggttaaa catgaacgag ttagcaaatc ttgacaacta tttaactgat cctgattatg
     2761 ctaaaccacc atatgaagca ccaattgatg aggaggatga agatgagtaa atctacctta
     2821 gaaatgagcc atcaagaatg gcttgaagac cgtaagaaag gcatcggagg ttcggatgtt
     2881 ggaacaattt taggattgaa taaatggaaa tctccttatc aactatggct agaaaaaaca
     2941 ggacaagtag tacttgaaga atcaggaagt gagcccgctt attggggtaa tgttttagaa
     3001 gaagtggttg ctaaagagtt tcaggaacgt acaggcaaaa aagtacgcag aagaaaccaa
     3061 gtatttgaac atccattaca tccattttta agagcaaata ttgatcggga agtagtggga
     3121 gaaaatgcca ttctggaatg caaaacagct aatcaatttc tcggtaaaga atgggaaggc
     3181 gaagaggtac cgcttagcta tctctgtcaa gttcaacatt acatgaacgt tctaaacaaa
     3241 gactattgtt acatcgctgt cttaatcggt ggtcaaaaat ttatctggaa gcggattgaa
     3301 cgagatcaag agctgatcga tacaatcact gaacaattag tagagttttg ggaaacaaac
     3361 gttcttggag gtatcgagcc aattattgat ggtagtcaag cgacagctga tttcttgaaa
     3421 gagaagtatg cagatgttga agacgttcaa acgacgttac caattcattt cgatgaacta
     3481 gttgaacaga aaaacgaact caaacggact aagaaagaaa ttgaatcagc tatccgtcaa
     3541 gtagacaacg agattatcag cgagctaggt aaacgtgaag ccagtatcgg tatcactcaa
     3601 aaaaacatca tcagttggaa atttgtccgt acgagacgta tgaactcgaa gaaactagca
     3661 gagaaatatc cagatgtcgc aaatgatgaa gagatttata acgttactga atcaagaagg
     3721 ctaaccgaaa gggagatcaa ataatatggc aacaaatgaa tcgttaaaaa atcaattggc
     3781 agcaaagcca cagaaacaag ttgcaccagg tcaattagga cttaaagctt tgatgaatac
     3841 accaacaatg agaaagaagt tcgaagaggt gcttcatgac aatgctaatg cttttatgtc
     3901 gaatgttatg actcttgtat ctaatgacag ttatcttgca gatagtgaac cgatgtctat
     3961 catgagtggt gcgttaactg ctgcaacatt aaatcttggg ctagataaga atttaggtta
     4021 tgcatattta gttccattca atagtaaaaa caagcaaaca ggaaaatggg aaaagaaagc
     4081 tcaattcatg cttggctata aaggatatat ccaattagcc caacgatcag gtaaatacaa
     4141 agcattaaat gtgatcgaag tttacgaagg agaactaaaa agctggaacc gactgacaga
     4201 agagtttgag tttgatccaa atggtagaac gtctgatgaa gtcattggat atgttggcta
     4261 tttcgagtta ctgaatggat tcaaaaaaac tgtctattgg accaaacaag aaatcgaagc
     4321 tcatcggatt gctaacaata aagatcgcga taagacaaag ttaagtggtg tgtgggcatc
     4381 tgattacaat gcaatggcac gaaaaactgt tttgagaaat cttctttcta aatggggaat
     4441 cttgtccatc gaaatgcaag aagccaccac atcggatgag agagtccaaa gggttcaaga
     4501 agacggcagc attattgctg aaacagaagt tgaagaagat attcctgaaa gaaaagaagc
     4561 agaggttata tctgaagaaa atgaagatgt acaaactgga ttatttgatg catctaatcc
     4621 gccgttaaac aaataatgag ggagctttct cccttgcttt tctagaggag aaatacgaat
     4681 gaacacagga tatgtcaaat tacatcgaaa agtgatgaat tcattcgttt ggaccaatcc
     4741 ttatatgtat aaattatgga acttgtgttt gatgaaagcg agtcatgaga atcgcaagat
     4801 actttttaat ggaaaagaga tacaagtgaa cagcggagaa ttcgtcacag ggcgcgatgc
     4861 tatcacatct gagatgaacg aaggcgtgaa acgtgaacat caagtgaaca gcggttctgt
     4921 atggagatgg ctaaaacaat ttgaaaaaaa cggaatgttg aacatcaaat caactacgaa
     4981 atacagcgtt atatcaataa aaaactggtc tttgtaccaa agcagtgaac aacaaatgaa
     5041 catcaaacgc acaacaagtg aacaacaagt gcacacaaac aagaatgaaa agaattataa
     5101 gaatgaaaag aataataaaa catcatcgtc gcaaccacgc aaaaagcgtg tttacgacac
     5161 cgactcagtt tactacattc tcgcggagga gttattcaaa cagatttgtc agaatcagga
     5221 aatcaaaaag ccgaatctgc aaagttgggc agataacatt cggaaaatga tcgagatcga
     5281 caagcggacc gaaaaccagg tacggggaat gattgaatgg agtcagcaca atgtgttttg
     5341 ggcatcgaat attttatctg ctaaaaaatt gcgagaaaaa tacgacacaa tggcagcgca
     5401 agccaatcgt gattataaaa caaaacaaac taaaacgctt gaatacgaga aatttagcac
     5461 agatgagttg cctatttgag aggaggcgta ggcatggaaa ctgttgggga aatcatggaa
     5521 aagctgatac agaaagtgct tgtccaacgt ggcgaatgtc ctgaatgcgg acagcctttg
     5581 tatggatggc gtacgaagaa ccctgatggc tcagaacgtt gtaagccaac ctgtatgcaa
     5641 tgtgggtata aagcattgcg agttcaggaa gacttacaaa cagaacgaat ttacaacgag
     5701 agcctgaaag caagagcaat caattttttc aaaggtggtt ctgttgtgcc taatcaagcg
     5761 ttgtttgatt gcacattgca gaattatcaa attgtcgatc aagaaacaag acaagcggtt
     5821 gaagtaacca aacgctttgt taattcagtc ttgttaggaa atccaagtca ccttgtttta
     5881 actggaaaac aaggaacagg taaaagtcac ctagcgatgg cagcggcttg ggaagtcttg
     5941 aagcgatcaa actacgataa aaaaatctta tttatcgggt tacaggaaat gctggatcaa
     6001 atcaaatttt cgtacaacaa tcctgaactc agaaaaacga ttgagggatc gttgattgca
     6061 gatatcaaaa cagcggattt agtcatcatt gatgatatcg gttcagaact aggaaaagat
     6121 gcatcagata gtcgagcgtt tggcataaac acgctaaatt cgttcttgga tgcacgacag
     6181 aacctagcaa cgattatcac aacgaacttg cttggtgaag aactgaaaaa agcttacggt
     6241 acgagaacaa tatcaagaat gtttgtcaac tctgatggat ttacgatggt attttctcaa
     6301 acagcagaca agcgcataaa accagtcaaa ggagcgatcg catgaatttg actaaacaag
     6361 aaaaaagaat ctgtcgtcag ataatgttgc aaattatagg tgatcgtgac atggacgaat
     6421 tatctcaaca agagagtcga atggttcgga agataagtaa gctaattatt tatcgggata
     6481 cagaaagatt tctcactgtt ttaggtaacg tctacgagaa tccagagtta ttggaggtag
     6541 agtaattgcc aaaaatatta gatgcatgtt gcggtagtag attgttctgg tttgataaga
     6601 acaattctga cgtaacattt atggattgtc gtcagcagta tgaagaatta tcaacaggtc
     6661 atgtgatcaa tgttgatcca gatgtggtcg cagactttcg cgatatgcct tttgaagatg
     6721 atgtgttcga tatggttgta tttgacccgc cacacttaag acatgtcggc gaaaactcat
     6781 ggcttgccaa aaaatatgga aaattagacg aactttggcc agaagacatc aggcaaggtt
     6841 ttgcagagtg tatgcgagtt ttacgacctt caggaacatt aatttttaag tggaacgagg
     6901 aacagatacc actttctgat gtgttagagg ctattggaga acagccattg tttggtaata
     6961 aacgaagcaa aacacattgg cttgtgttta tgaaaaaatt cagctaacgg aggaaacaaa
     7021 ggaggaaaag taatgaagat tgtattaaat aaatgttttg gtggctttgg gttgagccat
     7081 gaagcaaaaa tggaaatttt taaaagaaaa aatattgaag tattcccata catcaataac
     7141 tttagctatg actcagatga tgaatacacg agatacacag gccaaaagct aggttcgatg
     7201 gattttatct actatttcaa aaaagacccg aaaatcgaca aagttacagg aatttatagc
     7261 gaaattgacc gactgtacgg aattgctgat gattccagtt tttcaagtga ttcaaacaga
     7321 ggtgataagg acctcgttgc tgttgtcgaa aaactaggaa gtgaggccag tggaccatat
     7381 gcaagtctta aagtcgttga tatacccgat ggggctgagt gggaaataag tgattatgac
     7441 ggcgttgaaa ctgcacatta tggttttcaa acaggtagta tttagtccac taatgacaac
     7501 taaagaggag gcagaaggat gagtgaagat gaatactttg aacagtagtc tattaacgac
     7561 agagattttt aactggaaag gggtgtagtc atggacgcat cggaagtagt aaataaaatt
     7621 aatagtctca aagaggtttt cggagacgtc gaagtagtga taaacgcaca aggctatgac
     7681 aacggatttt ttaagcagat taccgacatt agcattcagc aaggaatgga agacgaagat
     7741 ggaaacttta tcgatgaagt agccatttta gtgacttgcg agtaagtaat tgacagctaa
     7801 agaggaggca gaaggatgaa aaaattgcac caactcatat ctgagaaaga aagcgaactc
     7861 caaaatttag aagatagttt gggattgggg tttccaattg ttgagcaagc taaaatgact
     7921 caaatcagtc atctacgact tgaattggaa gatttaagac aaatagaaaa atcaattcaa
     7981 ctcaacgaca accagaaaat cgtgttggag tggttgaaaa gcgagacaat tttaactaga
     8041 gaagcaccaa tattatctgt taatgctttt tctgataaaa atttactagg aaaattacct
     8101 gataaagtac gcaaagctta taaactattg gcttgtaaac aagaatatga agtcctatca
     8161 gcattcgctc aatggggatt agaacaggag gaagcggaat gaacaacaga catcgcagaa
     8221 taacaaaact aagaaaacag gaactgaatg tactaaagac aaagtttgaa aaagaatatg
     8281 gaatttcagc agaagaaaca tataaagtgg caagtcagtt tgttgctgat gcgagtaatg
     8341 ctattcgtaa gtttgggatt tcgatattaa atgatgatcg taaatgggag gaaatgagat
     8401 gaaaataaaa gacggatttt acgctagtag tcatggtatc ggcggtttaa tgctagacat
     8461 gccgataaag aaccctaaaa cacgtcagaa atcaaaattc aaaatcggtg acatggtccg
     8521 atgtaaagca gaagagttca tctatccgtt tcgtggatat gtagagcatg tctataatca
     8581 ttcagcaatc attcacattg aaaacacgat ggaatgcgat aagtggttag cgaaaagcaa
     8641 agataattta gcagtggctc gtttggtgga tatggaacta atcaatgaca aataaaaaag
     8701 ccggatcgct ccgactgatt caataaatcc aacacattta ttatatcaca taaaggagcg
     8761 gtttgacttg atgcaattgt tacgagaggt agatttcaaa cagacaagat gtaatgcgag
     8821 agatgtgctg aagaactttc ggcgtttgga gcggatggca ggtcgctctt tgatagatat
     8881 taagtcgccg attattacgg atatgccgaa ggcaccgaag cacggcaata aggcagaaga
     8941 cgcgatcatt cagatgatgg atatagaagc ggagagagac gcaatactag cggctttgat
     9001 ggctcttagt ctgattagcc gtcagatact ctactacagc ttctgtgacg taaacaagca
     9061 ctctaattat gaaatagggc aattgatacg aggatacgga gagaagaatg tagagaagtt
     9121 gaaatccatc gcattaatcg aatttgcaga agcatacaaa aaaggcgtgt tagttcagta
     9181 tcgttgattt tgtagggttt ttgtagggat agtgtagggt ttttgagcgg tttaacgtga
     9241 tattatggta gtgtcgaaag attagtgata ggtctgagac aaaataaaat gtaagggagg
     9301 aaatctccct catcgtttta acttaagctt cgatagacag caacggaaat attaagaata
     9361 aggatgtgaa tttcaactcc ttctaaattg ttcttattat ctatcatccg ttgttgtcta
     9421 ttaatttatg catcggagga aaaacgaatg gataaagaaa tcaaagtaac tgtcaaatta
     9481 gatttgactg aactaaaaga actgctcaac aaggctagtg accaagtcga acagttacaa
     9541 gaaactttag atgaaattgc taattttaaa atccaagttt cttagcagta tattttttag
     9601 cagctgcact cataaaatca taccaagtat cagaaaaata taacttaact aaataattaa
     9661 aaaaggtggg taaatagaaa tgacggcgtt aataatttca atttttgcgc tctgtcttaa
     9721 tgtctatatg attggattta aaaatggaca aaataaaaaa tagtagcagc cgagaataat
     9781 tttatagtgt cactgtggcg gaaatagaag acgcaaaggt ggaggtagga agcgtatggc
     9841 gcactatcgg gaccttgtac aaaactagaa aggactagta cgtgtgtggt gcgagcccta
     9901 gggaggaaca ggataaccgc ctgtgtgtag gttgctatta catattagat cactctttga
     9961 gtggtctttt tatttacata aaggaggcta cataatgaga aactactggt atatatcgct
    10021 aactaatgaa tatcctcgaa ccattgatga ttgttcagtg cgtgttgtgc gttctgtcca
    10081 aatcaaaaag aagtactcca ttgttgaaat gaccagagaa gctacgccaa aagagattga
    10141 taaatgcaaa cttctttatt gcggtcatgg tttctatgat gaaccaaaca ttcaaaataa
    10201 tattaacaag aatttgaggg attagaatgc aagaaatggc ttaaaaatct ccaatcagga
    10261 caaatcaagt tagacaaagt ttccgattta aagatattga ttgaagctga tttaatgcta
    10321 aaagatattg aaaattagaa aacaaaactc aacctaagaa gattgcgagg tggtgtgtat
    10381 tgaatggcaa gacaacgtga tccaagacgt gatgaagcca aaagaatttg gttagaatcc
    10441 aacggagaaa agcagttaaa ggaaattgca tctgaattaa atgtttcaga ttctcaggtt
    10501 agaaaatgga aatcgcaaga caaatggagc gctgaattga aaagtaacgt taccaatggc
    10561 aaaagtaacg ttactaatca aggtggcgct cctattggta atcaaaatgc taaaggtaac
    10621 aaaggaaaca gcagagcatc accgccaaag agaaataaga atgctcttaa aactggtgag
    10681 tatgaaacaa tattttttga cacgttaacc gataatgaga aggacatcta ttctagtttg
    10741 aatgatgatc cttcttttgc tttgtccgaa gaaatacgac ttcttaaaat aagacaactt
    10801 cgaatgatga aaagaatcca acaagctgaa gctggactaa atgatgaaga agtcgaacga
    10861 ttgcagcagc taagaaagat taaaactccg attgaaaaaa atggtaaaaa gctagaaatc
    10921 aagcgtgagg ttatgcaaga tgtgcagatt agcagaaaaa aacatcgcaa aattgatgat
    10981 attctttcaa ttgaagattc attgactcgg attagcaacc agttagctaa agccatcaag
    11041 caaatgaatg aactttatat gaatgaatac agaactgatt taattaaagc tcagactgat
    11101 aagatccaag ctgagacaaa tgaaattggc ggaaataatt caggtgaaga aatagaagaa
    11161 tggaaacagg cagttttaaa tgccgcaaac aaacgggcgg tgaaagaaaa tgaataatga
    11221 atttattcct tttgctgata ttggttctgc cattgattat tactatgata aaccagtagc
    11281 tttttgccaa gatattttgc atttgaatcc tgatgaatgg caagaaaatg ttttaaatga
    11341 tttagctgaa ttttcaaagg tttctgttcg ttctggtcaa ggagttggaa aaacagcatt
    11401 agaagcagga gcaatacttt ggttcttaac gtgtcgaccc tacgctaaag taatagcaac
    11461 agctccgaca atgaagcaac tttacgatgt actttgggca gaggtagcta aatggttaaa
    11521 tgatagcttg atcaaaaact tactgaagtg gacaaagacc aaaatttata tggttggtga
    11581 ttcagagcgt tggtttgcta cggctagaac agcgactaaa ccagaaaata tgcaaggttt
    11641 tcacgaggac catatgttga ttgtggtaga tgaagcttct ggtgtgtctg atccaattat
    11701 ggaagctatt cttggtacgc tatcaggttt tgataataag ctgttgatgt gtggaaaccc
    11761 taataatatt gaaggtgtct tttacgattc ccacaattca gaccgtgata aatacagagt
    11821 tcataaagta tcaagctatg atagtaaacg tacaaacaaa gacaatatag aaatgattct
    11881 taaaaaatat ggaaaagaaa gtgatgttgc tcgtgtccgt atttttggag aatttcccaa
    11941 aggtgcgttg gattcattta tcagtcttga aacggttgaa ttggctacag aaaaacaaat
    12001 tagtgattct ttagtcaata aaacaacggt tgctcatatt ggtgttgacg tagctcgata
    12061 tggtgatgat tctacgattc tctttcctag aattgctacc agggcattgg agtatgagaa
    12121 gtattcaaaa cgtagcacta tggaaacaac aggatatgtc atcaacatgg ccaagaatct
    12181 aatgagtcaa tatccgagta ttgataaagt gatgattaaa gtcgatgaca ctggtgtcgg
    12241 aggtggtgta accgaccgcc tagaagaact tatagaagac aagcattatc cttttgaggt
    12301 gtttggagtg aataacggtt caacatcaga agacgatttt tacgataatt taggtactca
    12361 actatgggga aacatcaagg aaatgttaga agaaaatatg acagcaaatc ttaacggaga
    12421 acagcctgtt attgaattgc cttctgatag ttcgttaatc aaagaattaa gtactcgcaa
    12481 attcaaaatg acaagtagaa gtcgtatacg tttagaaagt aaagatgata tgaaaaagcg
    12541 aaatattggt agtcccgata ttgctgacgc actggcttta gcgttttatg agccaccaag
    12601 tcactatcaa tttattcaat tttaggaggt gagtttttga ttagtacagt attatcttta
    12661 gagagatata agaagctacg tgttaaatat gcaacacaaa ttgaagatgg aatgtttgat
    12721 ccgaatggtt ttatagaata tatgaaacca ttttttgctg atcgcgaaag aaaatatcta
    12781 gcttatacta gcgaaaagaa tgaaatagac aatagaccaa agcctaacac tgatattgta
    12841 aaagttaata ataaacttca tgctggtatg tattcaattg tcgtagacca agcagtcaat
    12901 cattttactg gtatacctat caaatgggat tacgatgtat cggaacaaaa aagaacactc
    12961 attcaaagat taaaagataa attcttaaaa aatgatatag aacttccaac agttccagaa
    13021 gcttttaaca aattaacaag caatcttgat tccatgagat tcgcaatgct tgattctgaa
    13081 actgcaactt ttcaaggagc ttgtggagta gctttccgat tgttagagcc tgtggaagaa
    13141 gatgatggtt ggaagttaag agcaagtaat attgaacctt ggagagcaga aagatatgga
    13201 aatgccggaa tctatatcaa agaaaagtat gactcttacc agaaaaaatt ttttcaagaa
    13261 atgaaagtta tgacaagaaa taaaattctg acatatgctt gctatggtga tttgaatttt
    13321 gttacaagcg gaacgttcaa aaaaattgat gagaccgata accctttggg gacgattacc
    13381 ttggcagaat ttaaaaataa tacgaatcgt tattgtgatt ttgaagtagc tgaggaaatt
    13441 ggagatgcaa ttgatcgtgc tttgtctgat caacaaaacg aaatcgaaca atttaagctt
    13501 gcgtacatgc ttgttactgg cacaacaatg agcaaaggca ctgctaaaga aatgatgaat
    13561 cagctaggga ttatcaactt aaaagaccct actgcaaaag ctgaatatgt cacaaaaaaa
    13621 ttagcaaaag atttcaatga atatcatatg gatctattga aaaaacagtt ttacaccatt
    13681 tgtaaagcaa tcgattttaa cgatgaggtg tttaaatcaa acagttctgg agaagctcgc
    13741 aagtggcaaa tcattagcct agaagcgaaa acaaatacta aagagcaata ttttagagaa
    13801 ggattgaaag aatgcgcaga aacaattgct gcttttctta agtttcatga caaagtagaa
    13861 attgagcctg aaaaaattat ttttactttc tctagatctt tgccaactga tttaagttat
    13921 ttagctgaag ctttacctaa acttgcacca tacgtatcca aacgaactat tcagagccaa
    13981 attccatttg taacagatgt tgattatgaa aatgaaatga tggaattgga aagtggaagt
    14041 gcttatccag atagtgaata caattttggc ggaggtggca atagtgacga tagaaacgaa
    14101 gtattggacc aaacgtcgag aactggagga tcaagcaagg ctcaaacaag aaaatcagac
    14161 acttaaaaaa ttaactagtg tatttcctga agcactgaaa gagatacaag caaaactatt
    14221 atcacaagct gacttacaca atatcactta tccagaaatg atggagtttt acagtacaag
    14281 taatcagaaa aaatatcgtg aatatgtgga aaaaaattat aagtcattaa aaatgtatga
    14341 tgcaaaatac aaagagttta tcgatgaatt ttttccacca tttgactatg caaaagtcaa
    14401 tcgcttatta caaatacgat cagatgtatt taaaattctt gcagaatatg cgatggatgc
    14461 agatgtgaat caatattttt ctgatcgctt agaggaaatt cttcaaagaa catattcttc
    14521 taatgctaat gtttttgttc aacttttaaa cgttgatata ccaaattatt taccagaaaa
    14581 tgaaattaaa cattatttga actatccatg gtcaggaaag acattttcaa gaagactttg
    14641 gggaaatatt tcatcgcttg aacagaaact ctctaatgct attgtaaaaa gtgttgctag
    14701 tggagaaggc gttatacacg cattaaacac catgagatta gactcagaaa tttgtgacat
    14761 gtttaagtta gaagaatcaa agtataacaa agcgatagaa aatctcgttc gaacggagta
    14821 tgcaaaattt gcacaagatg gtattgaaaa atcatattta gaaacaggta ttgaggaata
    14881 caacgtattg actgcaaaag atgagagagt ttgccggatt tgtggaggaa aggcaagtaa
    14941 gaatccctat aaactgaaag atgctgtcat aggtgaaaat cgagcacctt tccatagtcg
    15001 ttgtagatgt acggatgttc ctaatttacc aaaattagga aaggatattg atgaagaata
    15061 tgaccgttta tttggcgatt tattagatga gtttgcacat gattcttttg gaattaattt
    15121 gaaacggagg aagtagaatg aaagattttt ttgaagcagt actaacaatt aatgtaaatg
    15181 ctgatattgc agaagcctac aaaacagcta ttgagtctga gaaccatcct aatggcttga
    15241 gagaccattg gaatggcaat tatgcctacg tggttattgg cgatcaaact gttaattatc
    15301 aagataatac tccagttgat aagaataccg ttaatttaac gattcaatta ttatctcatt
    15361 cattaccaaa tttaaaagaa acagttgatt ggtatgaaaa gatgggatgt attgttgtta
    15421 gaactgacta caaagaagga aagtctagta attaggcttt tttattttgt ccgaaatgac
    15481 gttaaactag cgcaatactg ggcttggttg aatggtgggg cgcaactatt aaaactcaaa
    15541 gcaatgcggg gcgtgaaaac gaatcgtggg gcgaaaggag aatgagcatg aaacacaaat
    15601 cattaatgcc aatgaatttg caatactttg ccgaaggtga cgatcaaaag ttttcttttg
    15661 atgacttcaa atcttttgtg gaatccaatg aagaagctca aaaatttatt cagtcacaat
    15721 ctcaaagtgt tgccgacaaa caattggaag cttggaaaca aaataactta gataaaatta
    15781 aacaggatac catcaaggaa tatgaggaat ctaagaaaaa caagtcacct gagcaaattc
    15841 aactggaaaa actacaagct gaatttgaag cagaaaaagc gttgcgtgtg acaagtgata
    15901 ataaagcatt tgttgcagaa caaattgctg gattagaact agatggagag ttaaaagagt
    15961 ctatttctca atttatgcta aataatcttg ttagttcgga tacagatttc actaagaatg
    16021 ctgttgaagg ttttacaagt gttttgaatg caattaatga gaaacatgca gatgcattaa
    16081 aagaactaca aatgaagtct gcatttggtg gaactcaaca atcgaataac caggttcagc
    16141 agaacaatga aacattaaca aatccagaag aacaattagg acaaattctt caacaattta
    16201 actaggagag tgaaaaatta tgaaaaaaac atctttaaat aatttagagt atttggatat
    16261 ttcaccagcg attaatgcta tgcaagtacc aaatacacct tttttaagct atttacttgg
    16321 tgctggaaaa acagagccag caaactcgac agaaattaaa tggcgtgaat atgatatcaa
    16381 caacgatgat tcttctgaaa aacttgaggg cggagaatat ccagatgctg aatcaggtcg
    16441 aacttggttt aacaactata ctgaaatttt tagaaaatca acctctgtat ctggtacatt
    16501 agatgctatt aatgtgaatg gagtcggaaa tgaattaact aatcaagtag cactacgtgg
    16561 tatggaaatg aaaattgatt tgaaccgaaa attgattact ggtgtaaaag ctgatgaaaa
    16621 tggttctaaa ggtcgtcgaa tgaatgggat tttgaacttg atcaattcag caaataaggc
    16681 agaaacagcc actgcgggtg cagtaacaag aaaagatatc gatactttat ttaaattgat
    16741 gtatgaaaaa ggttatatgg gagaaaaact atgcttgatt tctccagata tgcaggagtt
    16801 aatgactgat gagttagatg gaaaatcaac aaaaattgtt cagttcgggg aaagagtaac
    16861 ttttggattg caaattggaa atatcgtgtc taattacggt acaggtattg ctctactaga
    16921 accatcattg ccaaaaggaa caattgccgc aatcgatact aattatgtga aactacgtcc
    16981 attacgtgaa tggagagcag aagaacttgc aaaaacaacg gattctagac gtatcggtct
    17041 tgtaggtgaa tactctcttg aatacaatgc ttcaaactct ggggcaattt taaatttaaa
    17101 gtctgaataa aagggagtta gtactccctt ttttgatagg aggaattaca gtggtaaaaa
    17161 aagatgaaac taaaaaagat gaagtcgtga aatatagagt aggtaaaact aaaaattttg
    17221 ttgggtttgt tcatcctaaa actcgtagat ttatcacagc agattcaaat aacgaattta
    17281 tcatttctat agatgataaa gaagcaattg caattttgga agatgcaatt gatgttaatg
    17341 aaatttagga agtgatctga tggatgaatc gctaaaaacg gaaatcattg agtctacaaa
    17401 agaagatttt ccagatttga gtgaagaacg cataactaat ttattagaaa taattttgct
    17461 agaaattgaa tcatacaaca cttgtaaaaa tgatatttca tgggaaaagt taaaaagcgt
    17521 gattagtgaa gtgttgtata aaataataaa aaatgaatca gaaaaaacag tatcttcagt
    17581 tagacgtggc gatacaacga ttagttatgc ttcaacaaca aatgatgtta gtgagttact
    17641 tctaggctat ggtgatttga tacgaagagt tattggttgt ggaggattgg agttttttta
    17701 atgaatgaag cagatatttt agaaactact tatgaagata gttgtattat tgaaagactg
    17761 acggacattg aagattctaa tacaaatatt actattcaag attacaaaaa agtatatgat
    17821 aatcctattt cttgcgctct ttcacaaggt caaatcgatg gactagcagt catagaagat
    17881 ggagagatgg taaatgtttc aactgacaca tataaattat ttgttcatcc taagattaaa
    17941 ctaaaaaaag gagatcgaat aacaataact caaaaggcca gtggcttaat tttttctcta
    18001 tttgctacta agccttttta ctatcctagt cattgtgaag tgaatttgat aggaagtgag
    18061 aaaaatgggt aatctcaaat atgaatcaaa tgcagaaaag atcattgaga attttaaaaa
    18121 tatgactgta attgctcaaa aagaaggaat atccttcgtt aacgattcaa tgaataaagt
    18181 cgttagttta gctaaaccat taactcctgt aaaatcaggt aatttaaggc gaggatatcg
    18241 tgtagtaaaa gctagaaaac tatcaagcgg tcgaattgtt ggagcagtta taaacaatga
    18301 acattatttt aaatatgtag aagaaggtca taggactaaa aatggtggct ttgtcaaagg
    18361 gaaattcatg ttaactcgtg caacgaatct tgcaaatatg tcttatattc ctcgaagatt
    18421 taaacaaatg gcaataaaaa tcgttaagaa aggaaagtaa catgaaagat gaaatcattg
    18481 ctgcaatcag tagcaaatta aaagaaatct atcctgatgg gacaatatat cttgattcag
    18541 ttatgcagtc aactaaagat ttttatttcg ttttatcagt aatggaatct ggaactgaaa
    18601 atgtaggaat tgatattcaa aatgtttctt tc
//
LOCUS       DADVXK010000052        18049 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.052, whole genome shotgun sequence.
ACCESSION   DADVXK010000052 DADVXK010000000
VERSION     DADVXK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.052"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(57..1793)
                     /locus_tag="KB909_001678"
     CDS             complement(57..1793)
                     /locus_tag="KB909_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBB6837701.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(1790..2494)
                     /locus_tag="KB909_001679"
     CDS             complement(1790..2494)
                     /locus_tag="KB909_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6837702.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            2625..3128
                     /locus_tag="KB909_001680"
     CDS             2625..3128
                     /locus_tag="KB909_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBB6837703.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            3088..3426
                     /locus_tag="KB909_001681"
     CDS             3088..3426
                     /locus_tag="KB909_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBB6837704.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            3447..4865
                     /gene="ffh"
                     /locus_tag="KB909_001682"
     CDS             3447..4865
                     /gene="ffh"
                     /locus_tag="KB909_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBB6837705.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            4977..5555
                     /locus_tag="KB909_001683"
     CDS             4977..5555
                     /locus_tag="KB909_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBB6837706.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            5559..6080
                     /locus_tag="KB909_001684"
     CDS             5559..6080
                     /locus_tag="KB909_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6837707.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(6159..6713)
                     /locus_tag="KB909_001685"
     CDS             complement(6159..6713)
                     /locus_tag="KB909_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6837708.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            6966..7241
                     /gene="rpsP"
                     /locus_tag="KB909_001686"
     CDS             6966..7241
                     /gene="rpsP"
                     /locus_tag="KB909_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBB6837709.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            7253..7504
                     /locus_tag="KB909_001687"
     CDS             7253..7504
                     /locus_tag="KB909_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBB6837710.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            7629..8420
                     /locus_tag="KB909_001688"
     CDS             7629..8420
                     /locus_tag="KB909_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837711.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            8590..9111
                     /gene="rimM"
                     /locus_tag="KB909_001689"
     CDS             8590..9111
                     /gene="rimM"
                     /locus_tag="KB909_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBB6837712.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            9101..9862
                     /gene="trmD"
                     /locus_tag="KB909_001690"
     CDS             9101..9862
                     /gene="trmD"
                     /locus_tag="KB909_001690"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBB6837713.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            9998..10345
                     /gene="rplS"
                     /locus_tag="KB909_001691"
     CDS             9998..10345
                     /gene="rplS"
                     /locus_tag="KB909_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBB6837714.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            10718..11380
                     /locus_tag="KB909_001692"
     CDS             10718..11380
                     /locus_tag="KB909_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837715.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            11459..14686
                     /gene="fss3"
                     /locus_tag="KB909_001693"
     CDS             11459..14686
                     /gene="fss3"
                     /locus_tag="KB909_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6837716.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            14800..15114
                     /locus_tag="KB909_001694"
     CDS             14800..15114
                     /locus_tag="KB909_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6837717.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            15127..15501
                     /locus_tag="KB909_001695"
     CDS             15127..15501
                     /locus_tag="KB909_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6837718.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            15511..15855
                     /locus_tag="KB909_001696"
     CDS             15511..15855
                     /locus_tag="KB909_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBB6837719.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            15926..17278
                     /locus_tag="KB909_001697"
     CDS             15926..17278
                     /locus_tag="KB909_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6837720.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            17338..>18049
                     /locus_tag="KB909_001698"
     CDS             17338..>18049
                     /locus_tag="KB909_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6837721.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGML"
BASE COUNT         6029 a         3231 c         3842 g         4947 t
ORIGIN      
        1 tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc tcttttttac
       61 attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc
      121 gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc ggtcccgcct
      181 gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg ttcctgatcc
      241 tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc tgttgcctga
      301 tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc aattagattt
      361 ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt tccaatcaat
      421 cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat ttgctggaaa
      481 taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt tgacagctgg
      541 atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa
      601 gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt aaaaccaatc
      661 agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc cttttgtagc
      721 ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg tccggtacct
      781 tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc tgtaagggtg
      841 atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg aatgagtttt
      901 ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac gtttaaatgt
      961 agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat caggaatacg
     1021 ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt acacgcccga
     1081 tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc ttcccattga
     1141 tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt ttttagtacg
     1201 ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat cattcctgca
     1261 agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact ctcagttctc
     1321 ggtaaaaaac cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg gccacttttt
     1381 ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt gcgcaaagcg
     1441 ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt tcgctgttca
     1501 ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat taaagtaatc
     1561 cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc tgcttggagg
     1621 ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc
     1681 tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa
     1741 ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt catcgtttgg
     1801 gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg tgttttggat
     1861 ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg
     1921 cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca cggtcttttc
     1981 gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc agatggtcgt
     2041 ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat agatattcag
     2101 gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt gctttcatac
     2161 gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca cctatttcta
     2221 ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc ggtgtttcat
     2281 ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga agcatcacat
     2341 ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg cctccatctg
     2401 tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc gttacaatag
     2461 aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa taggtttcat
     2521 tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag aaataaatgg
     2581 tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg
     2641 catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta ccagaattga
     2701 tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc ggcggattac
     2761 caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg tggaaagatc
     2821 aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa aatggcgcga
     2881 tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg aaggaaaaaa
     2941 gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata aaaaaaaatg
     3001 gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc tctgatgaag
     3061 aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg
     3121 ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat ggaattatat
     3181 tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag ccgacaagca
     3241 gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa aaaactccat
     3301 cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc atatattaca
     3361 gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca agcaatcgaa
     3421 gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa cgtctccagc
     3481 aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta aaagaaatga
     3541 tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta gtcaaagatt
     3601 ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt ttatcacctg
     3661 cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt tctgaaacag
     3721 cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt cttcaagggg
     3781 caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat gaaaatgctc
     3841 gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat
     3901 taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc ccggtagaga
     3961 tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata
     4021 cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa atcaaagaat
     4081 tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa gatgccgtca
     4141 acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc actaaacttg
     4201 atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc gcaccaatca
     4261 aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca gatcgtatgg
     4321 ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg cagcaagact
     4381 acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca ttcgatttca
     4441 atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa gatctaatca
     4501 aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag
     4561 atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga gcaaatcctg
     4621 atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg
     4681 aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag caaatgtcca
     4741 aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac
     4801 taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga
     4861 aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg gagcttttct
     4921 atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg gcacagatga
     4981 gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact gtctggggtg
     5041 ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt aatcaagccg
     5101 gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat
     5161 tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta atggaaaaca
     5221 aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct
     5281 tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt tctaatggaa
     5341 aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt cctctttcag
     5401 atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc acaacaatct
     5461 atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt ttccgcaaag
     5521 aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc atattttatg
     5581 gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa tggctttttg
     5641 acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc gatacgacca
     5701 tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa gcaatttatc
     5761 cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca gatgctgagg
     5821 tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa ggaaaagata
     5881 tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa atgattgatg
     5941 aatggtatat ccagattacc cctgtattat taggggacgg gattccttta ttccaaaaag
     6001 gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa tttatcgaat
     6061 tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat gcagaaatgt
     6121 cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa tttgttagaa
     6181 aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc aacgatatta
     6241 ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt
     6301 ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa gccgccgatc
     6361 ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact gtgtccataa
     6421 ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg gttgtattca
     6481 ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg agtccattca
     6541 gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc atcgattttt
     6601 acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc tacttttttg
     6661 ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt catacgattt
     6721 ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga gcaaataaaa
     6781 acacttactg acaaaagcta catagaagat agattactta tttttaacaa aaaagaagtc
     6841 taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt
     6901 tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg aggtggaaat
     6961 aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt ccgttttacc
     7021 gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa actgtaggta
     7081 cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta gttcttgact
     7141 ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca aaagaaggcg
     7201 ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg atatgaaaga
     7261 tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg atcaagtcaa
     7321 gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg ctcctgaaga
     7381 tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca caatcgttta
     7441 cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa
     7501 gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt tttattaatt
     7561 gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga ggagggagtg
     7621 aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta agcgcttgta
     7681 gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct gaaactgtta
     7741 ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca atggctacct
     7801 caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca aatgttccca
     7861 tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca catacaaagc
     7921 aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat gctgacgaat
     7981 tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct tctagtcaag
     8041 aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa gtggacttag
     8101 gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt gaatggcaag
     8161 aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat cccttactat
     8221 tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct gaacaatttg
     8281 gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta agctggcaag
     8341 aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg aagatggcag
     8401 tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt aactccaagt
     8461 cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct taatacctta
     8521 aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa aaagaaatgg
     8581 ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa
     8641 ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa aaaaggaacg
     8701 gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa aagtcatcgc
     8761 aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa tgatgtggaa
     8821 aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct agctgaaaat
     8881 gaattctatt accatgagat catcggtctg catgtattag aagatggaac tgagttaggt
     8941 aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca acgtccgaaa
     9001 aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga tttagaagct
     9061 ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg atgtattgac
     9121 tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta aggctgtaga
     9181 taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata acaaacatca
     9241 gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag tccagcccat
     9301 ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct
     9361 tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt cacaagaaga
     9421 acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc gcacattagt
     9481 gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag gtgcgatggt
     9541 catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga cttcagctca
     9601 aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc cggcagaata
     9661 taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga ttgaagaatg
     9721 gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt tggaaacact
     9781 tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag aacaagaaaa
     9841 aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg ttgataatat
     9901 gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg ctgtgagaaa
     9961 agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa tcgaagaatt
    10021 aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt
    10081 tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag gtgttgttat
    10141 caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt ctaacggagt
    10201 gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg aagtagttcg
    10261 ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg gaaaagctgc
    10321 tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct gaaatttgtg
    10381 aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt aagccatttt
    10441 tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag attgtccgac
    10501 attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga cgacaaatat
    10561 aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca agtttctcaa
    10621 agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa gttgatgtga
    10681 taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg atggacgtat
    10741 catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat tcatcgaaaa
    10801 acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc caaattctgc
    10861 accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat tgattagtat
    10921 aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag aattattgga
    10981 aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt acgaacaaaa
    11041 atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag gagatatacg
    11101 tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac tgctgttaga
    11161 actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga caaagtttcg
    11221 aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa gaacgaacaa
    11281 aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca aaatttataa
    11341 gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta aatcagacgt
    11401 tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga tttattttat
    11461 gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat tatgccaaac
    11521 aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc atccacaaac
    11581 ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat ttagcgatgg
    11641 tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg tgaagcaaga
    11701 tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg gttatgagaa
    11761 aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat ggaaggaagc
    11821 tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag aagttaatgg
    11881 ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg cagccattga
    11941 gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc ataactccac
    12001 agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct tgaatttatc
    12061 ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga acggcaatca
    12121 actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc taaagaagtc
    12181 agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt tgatggcggg
    12241 ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg agggttcttt
    12301 gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg ttttccattt
    12361 agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag gcattgcgac
    12421 attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag tgccagctcc
    12481 ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga ctatttctgt
    12541 gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg gggtggaaac
    12601 aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg ccattcgcaa
    12661 agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag gtcatgcgga
    12721 aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga ccgaaaccaa
    12781 agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga actatgtcaa
    12841 tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa tcactggtga
    12901 aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta aagctgagtt
    12961 taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca aatggagtga
    13021 ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg tgactttgac
    13081 tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt attactggca
    13141 agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg tttccatcaa
    13201 aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg caaaagaaca
    13261 agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg ggactgccga
    13321 aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca gtgagattac
    13381 aggtgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg atggctatgg
    13441 caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg ctccagaagg
    13501 atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata aagcggatta
    13561 cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac caattaaaac
    13621 ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct tgaatcgttt
    13681 gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga cttggaaaga
    13741 cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat tgagctataa
    13801 cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg tggaagcgac
    13861 aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg aaacaaccgc
    13921 aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat taaccgcaga
    13981 acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca agaaacccta
    14041 tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag cccaaactgt
    14101 caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag aagatggttc
    14161 gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga ttacccatga
    14221 tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac ttccggataa
    14281 tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg acaaagaatt
    14341 cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag gtacaagttt
    14401 taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac acaatgagga
    14461 tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac caagtgcacc
    14521 agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc ctacagtaaa
    14581 gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg ggtttacctt
    14641 gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg atgtgatgaa
    14701 acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg gtcgcgctat
    14761 ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa atttgttgtg
    14821 ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga agttttaact
    14881 gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta ttccagtaag
    14941 caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa ggattttgat
    15001 caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta tgagattgag
    15061 aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc ataggaggaa
    15121 aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt tgggaaatta
    15181 cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac ggttagtaac
    15241 gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat gatccaagtt
    15301 agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt agagttggtc
    15361 aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac tgtcaattgg
    15421 ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa ttctacaaac
    15481 caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca tattttagat
    15541 tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa agcattaacc
    15601 tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg taacgatgtc
    15661 gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt tatggttatc
    15721 gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat tggtgtggaa
    15781 atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca actccctata
    15841 gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat gaagcttttt
    15901 tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg caggagatca
    15961 gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag
    16021 cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac tttctactat
    16081 agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg ttctttcagg
    16141 aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt tgtggcatcg
    16201 acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac aaactcagag
    16261 tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca gttacttccc
    16321 caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa tttcactggg
    16381 aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc tatattgtga
    16441 actagtagaa aaggaactca aagactccta tgtggagtac actttactgt atgatataat
    16501 tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc gattgatgaa
    16561 aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg gcacaggtgg
    16621 tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg atgccgagct
    16681 ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa tgcctcatgt
    16741 ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc gcatgatgac
    16801 tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt atgcgtttct
    16861 tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg aaatgttaac
    16921 gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt taggtcgtca
    16981 atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt taggagacgg
    17041 gattcgcgat caatttaatt tccgggtggc tttgggtcgt atgagtgaac tgggatattc
    17101 catgatgttt ggcgaggttg ataaaaaatt ctttatgaag cgtatcaaag gtcgaggcta
    17161 tgtagatacg ggagggagtg tgattagtga gttttatacg ccacttgtac caaaaggata
    17221 tgatttctta agggaaatta gcgacattgg tggattaaac gttaatacgg aaggataaaa
    17281 taatagtatg tagcctagga gtgtcaagaa tcctgggctt tttttacgag gtgatttatg
    17341 acatttttag atttattcgc tgggattggt ggcttttgct taggtatgga acaagcgggt
    17401 caccagtgta tcggcttttg tgaaattgat gattttgctc gccagagtta taaggcaatc
    17461 catgatacaa gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga cgagtttatt
    17521 caatctctcg gaccagtgga tatcctttgc ggtggatttc cgtgccaagc tttttcaatt
    17581 gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga aatcgctcgg
    17641 ttcgccgcta ttctccaacc taagttttta ttccttgaga acgtccgggg attactcaat
    17701 cacgaaggag gggctacgtt cgagacgatc ctccgaacgc tggatggatt ggggtatgat
    17761 gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaaaccgtga gcggatcttc
    17821 cttatcggac attctcgaga cgcatgtacc gaacaagtat ttcctatcat tggatcgtct
    17881 ccaacatctg atcaaaacat cagaaactta ttaaatatca acccttccaa tcgaggaatg
    17941 gggggacaag tctatgggtc agatgacgta gcgcctacct tgaccggtga tgaaggaatc
    18001 aaaatcgcat tgccggtaga tgatggaatt tctgtagcgg gtatgttac
//
LOCUS       DADVXK010000053        17903 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.053, whole genome shotgun sequence.
ACCESSION   DADVXK010000053 DADVXK010000000
VERSION     DADVXK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.053"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(9..1487)
                     /locus_tag="KB909_001699"
     CDS             complement(9..1487)
                     /locus_tag="KB909_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837722.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1785..2720)
                     /gene="murB"
                     /locus_tag="KB909_001700"
     CDS             complement(1785..2720)
                     /gene="murB"
                     /locus_tag="KB909_001700"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBB6837723.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2793..3713)
                     /locus_tag="KB909_001701"
     CDS             complement(2793..3713)
                     /locus_tag="KB909_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6837724.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3826..4578
                     /gene="xth"
                     /locus_tag="KB909_001702"
     CDS             3826..4578
                     /gene="xth"
                     /locus_tag="KB909_001702"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBB6837725.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5442..5975
                     /locus_tag="KB909_001703"
     CDS             5442..5975
                     /locus_tag="KB909_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBB6837726.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6465..6989)
                     /locus_tag="KB909_001704"
     CDS             complement(6465..6989)
                     /locus_tag="KB909_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837727.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(6982..7455)
                     /gene="tsaE"
                     /locus_tag="KB909_001705"
     CDS             complement(6982..7455)
                     /gene="tsaE"
                     /locus_tag="KB909_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBB6837728.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7578..8558)
                     /gene="pta"
                     /locus_tag="KB909_001706"
     CDS             complement(7578..8558)
                     /gene="pta"
                     /locus_tag="KB909_001706"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBB6837729.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8711..9391)
                     /locus_tag="KB909_001707"
     CDS             complement(8711..9391)
                     /locus_tag="KB909_001707"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6837730.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9517..10386
                     /locus_tag="KB909_001708"
     CDS             9517..10386
                     /locus_tag="KB909_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6837731.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10412..10927
                     /locus_tag="KB909_001709"
     CDS             10412..10927
                     /locus_tag="KB909_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837732.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(10974..11567)
                     /locus_tag="KB909_001710"
     CDS             complement(10974..11567)
                     /locus_tag="KB909_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837733.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11592..11771)
                     /locus_tag="KB909_001711"
     CDS             complement(11592..11771)
                     /locus_tag="KB909_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837734.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11848..12357)
                     /locus_tag="KB909_001712"
     CDS             complement(11848..12357)
                     /locus_tag="KB909_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837735.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12453..12833)
                     /locus_tag="KB909_001713"
     CDS             complement(12453..12833)
                     /locus_tag="KB909_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6837736.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13163..13912
                     /locus_tag="KB909_001714"
     CDS             13163..13912
                     /locus_tag="KB909_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBB6837737.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14096..15373)
                     /locus_tag="KB909_001715"
     CDS             complement(14096..15373)
                     /locus_tag="KB909_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837738.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15452..16096)
                     /gene="pcp"
                     /locus_tag="KB909_001716"
     CDS             complement(15452..16096)
                     /gene="pcp"
                     /locus_tag="KB909_001716"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBB6837739.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16295..17239)
                     /locus_tag="KB909_001717"
     CDS             complement(16295..17239)
                     /locus_tag="KB909_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBB6837740.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17241..>17903)
                     /locus_tag="KB909_001718"
     CDS             complement(17241..>17903)
                     /locus_tag="KB909_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBB6837741.1"
                     /translation="GVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQGMLELLGTS
                     FVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGIFRMIFAAF
                     NVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCWFFGQVLFI
                     GGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKLAKKYYPGK
                     GQ"
BASE COUNT         5193 a         3666 c         3106 g         5938 t
ORIGIN      
        1 cataaatact agctgatttt ttcagttaaa tgtctatttt tttctctgat gatggtattt
       61 ccaaaatatt cccagtcatc tggagtcggt ggatttttcc aaattatctg ttctttatta
      121 aatttttcaa gtaaacaatc agataaataa atattcgtac gagaagtgat tcgactctca
      181 atcacaatat tgtaattttt aaatcctttc acttgagaaa taatgtaatc ggtataagca
      241 gatccttgcg aaaaatcaat acagacatga atcggtgctt caaaatatga taccggacaa
      301 ataccgacca ataaaaagag ataatcataa aataagcgaa tcatgaaacg ttcatctttt
      361 cccaagaaat agcgtttatt ctcttgtatg accttttgga ttgctgtact gaatattgga
      421 tacgtctcga agaaaaactg tagctgcttt ttagacgtaa agctagtcat ctcaaagtcg
      481 aatatccaat tttttcgatt gacatgcatc atacccatac gaagttcttt tcgtatatat
      541 agtctttctt cttcagagat ttcaatcgaa aatggtaatt gatcaatcaa ttccactgac
      601 attttttgac taatcatgtg gatatcatga aaatgagctt ccgcaagtcc aaatgcgcca
      661 tctaattcaa attcttcttc cgtgatcaaa aacaacatga tataagaaat ctcatcaatg
      721 atctgctctt tagggatatg aagaaaagaa atatgtgata aatccttgat gatcttcatt
      781 ccttctgagc tcttaaagta ttcatctgaa aagaaacgtt ttccgattgg ttgattccca
      841 taggccctca acaaactaat agtggttagc aaattgaatt tgattcgttt tgttgcagac
      901 agttttaaat tgaacagata ttcaaaatat tgcacgatac tctttgcttc attcatgacg
      961 ctttctctaa atggcataga aaaaccatta aagaccccga aatatacccc aaataatacg
     1021 ttccgtatgt ttatttcttc cccaactaat atgtttttct ttaactttat ttgatgctgt
     1081 tcaagaaaag agactaattc tcttcttttt acataggctc ttgatatgct taaaaaatga
     1141 ttctctgcaa atttttcgat cgttactttt gaatccacga tctccgttaa cagtcgagca
     1201 atttttgatc gttgaaagta gattcttctt aaatttttga tatccgtcaa attcagacgt
     1261 tcgacatgga tctctgcttc ttctgaaatt tggatctctg gctttgtttt gaattcagta
     1321 aattctttat ttaattctat gatataattt cttgttttaa atttagacaa acctaatgtt
     1381 tcatataact taggcagcac tacataattc tttttctcaa attctaaata tctagctagc
     1441 agcagttttt ctctatcttc ctcttctata aggtaatcca acttcatatc ctacacctca
     1501 aaaaatgcct cataccaatt acttgatatg cagatgaaag ttcatctttt cacctatact
     1561 gattttatga tggattatgc ttgttttttc atcagttatt ctcatttttt atcttttttt
     1621 tgagaatatt gcaaaaaatg gaaaaattta tgaggaaata ttctatattt tttgttttat
     1681 tgtgttaaaa tgtacaagat ttgcgccatt tgcgtaaaca accacaaaaa agagcaggac
     1741 ggccaccgtc ctgctctttt acttatttta agttccatta cttattaatt ggctaaactt
     1801 ctgcttgttt ctgatattgc ttgtttttct ccaatgatcc gcacttctgt ttctaaagac
     1861 acatcaaatt tttctttgat tacttcttgg atgtgcgcaa tcaattcaat ataatctgtc
     1921 gctgtcgcat gatcgatatt gacgatgaat ccagcatgtt tttcagagac ttgtgcaccg
     1981 ccccatttca ggccttgcaa tcctgcttgt tggatcagct gacctgtata gtgtcctact
     2041 gggcgcttaa agacacttcc gcatgaaggg tattctaatg gctgttttga ttgacgcaat
     2101 tcggtcaact catccattct tgctttgatt gcttcataat cccctgtttg caaactgaat
     2161 cgagcttcca atacgatagc acgtaattct tggactttac tgtgacgata agaaaatacc
     2221 atttcgtctt ttgtcaaagt tttcaatgtt ccatcttcaa gcaaaagatc cacttcagca
     2281 aaaacatctt tgatctctcc gccatacgca cctgcattca tataaaccgc tccaccgaca
     2341 cttcccggga tgccgcaagc aaattcaaat ccagtcaatg attctgccaa agctgcataa
     2401 gtcgtatcaa tcagtgaggc acctgcttcc gcaatgacca tcgttccttt gacatgaatc
     2461 tgtttcattt cagtcagcat gatgactaca ccgcgaatcc cgccatcttg aacgatcaga
     2521 ttgcttgcat ttcctaatac catccaaggt atatcatgga ttcggcaata atcgatgatt
     2581 tgctttactt cttcttgttt tttcgggaat gcaaggacat cagctggtcc acctgttttc
     2641 gtaaacgtat agttcatcaa tggttcatca aacaatatag taatcgtggc taagctttca
     2701 actatttctt ctttattcac tgaggatttt cctttctttt ctcaaacgtc ctcattattc
     2761 tatcacgctt aatacaatct tgccagtctt gttcaaagtt gatgacggta gtgatcttta
     2821 agcacttcct cacataattc atgacttctt acaacttctt tttgtttaag caattctgtt
     2881 tccgatttac ctaaacggat ctgagaaaag aaggcctcta ccattggctc aaacccgcgt
     2941 ttgactagcg tgtttgtcca gtcgccaaat tctttcactt tttttccatc agcatcttga
     3001 atgacaagct gggtcagatc gtttacttca taagtaccat ttttacttgt tacttgatat
     3061 ttttctatat tagcgccact tgctaaatcc atcgttaaaa tagccgtttg attttgtgtt
     3121 tctaattgta aaatggcata ttccaaaaat tcctttgttt ctcttatctg gtattttgtt
     3181 ctcaaaatgg gttcatctaa taaatacaca gctgtatcaa taagatgtaa aaacaaatca
     3241 taaaggacga actctgtcgt ttcttttgcc gctattcgat ttttttgcag gtggatcaac
     3301 cgcttatctg ggatacgttt caattcttct accataggag caaagcgccg gttgaaaccg
     3361 atcatcaaaa ttatttggtt cttatcagct aattcttgca attcacgaac ttcatttaga
     3421 tggacactca gtggtttgtc aatataaaca tggataccat tttctagaca ttttttggct
     3481 aattcataat gtacttttgt tgctgcgtgg atcatacatg cttcgatttt ttcttctaaa
     3541 agctcatcga tcgtttcata tagatgttgg aacccgtact ctttttgaat tctttctttt
     3601 gtttctttat ttcttgttgc aaaataaaaa tcaagtgttc cttgtttttt cgcataagtt
     3661 ggtaaatatg ctttttctgc gatattccct acaccgatta caccaatctt catctacttt
     3721 cctcctggat catttagtta ctttcatctt acaccatttt tttctaaaat gaggtacaat
     3781 agtatcgcaa aggtaaggaa attaattcga aggagtgtgc ttttattgaa atttatctct
     3841 tggaacgtaa acgggcttcg tgccatcgta aataaaaatt ttttagaagt ttttcatgag
     3901 ttagacgccg attttttctg tctgcaggaa acgaaactcc aagcaggaca aattgattta
     3961 gatcttccag gttattatca atattggaat tacgcggaac gaaaaggcta ttccggcaca
     4021 gcgatttttg ctaaaaaacc agcattgaat gccacttacg gaatgggtat cgatatccat
     4081 gatacagaag gccgtctgat tactttggaa tattccgatt tctttcttgt aacctgttac
     4141 acgccaaatt ctcaaagcga attaaaacgt ttagattacc gattagaatg ggaagaagcc
     4201 ttttataatt atttggaaaa tctaaaaaaa caaaaaccag tcatcgtgtg tggggatcta
     4261 aatgtcgctc atcaaaagat tgatttgaaa aactggaaaa cgaatcaaaa aaatgctgga
     4321 ttcactccag aagaaagagc ggctctttct cgactgttgg ataacgggtt tatcgataca
     4381 ttccgttatt tttatccaac ccaggaaggt gtctactctt ggtggaacta ccgattcaat
     4441 tcaaggaaaa acaatgctgg ttggcggatc gattactttt tgacgagcaa agatttagag
     4501 ccaggactag ctgatgcaaa gatccatacg gacattatgg gcagtgatca ttgtccagta
     4561 gaattagatt tgaaataaag aggttgtgaa aaagtcgttt agtttcgagt attaagaaaa
     4621 attttgtgaa aatggctttc cacattttgc ataaatttgg cataataccg agaaactggc
     4681 ttttgaacac tgtttatcga gagattgtga aaaagctgtc ctgcatcaag taataagaac
     4741 agccaaacaa aaatagttcc tcatattttt cgtttggttg ggcttattac cgcagataca
     4801 agcttttgaa caccgtttat taagaggttg tgaaaaagct gcactgcatc aagtaataag
     4861 aacagccaaa caaaaatagt tcctcatatt tttcgtttgg ttgggcttat taccgcagat
     4921 gcaagctttt gaacaccgtt tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat
     4981 aagaacagcc aaacaaaaat agttcctcat atttttcgtt tggttggact tattaccgca
     5041 gatgcaagct tttgaacacc gtttattgag aagttgtgaa atcagcgtcc tgacctgagt
     5101 attagagaaa caaatggcaa aatagttcct catattttgc tattttttga gctaataccg
     5161 agggtcagct gattgaacac cgtttagtgg agaagttgtg aaaaagtcgc ctactttcga
     5221 gtcgtaagaa atttttttga aaatggttcc tcacaacttt gcataaattt gacttaatac
     5281 cgagaagtca tgatccccat ctaactccaa atcacaagga atgagttcaa aaactagctt
     5341 ttctcaacaa atattacata aaaaattcta tgttttttgt taaatttatt tgcttttttc
     5401 aaaagtatgt tacagtaatt tcccaaggag gttttacaga aatgaatttt gttgccatgg
     5461 attttgaaac tgccaatcat cagccttata gtgcttgttc tcttgcgcta gtcatggtaa
     5521 aaaatagcca gatcgttgat gaattctata cattgataca gcctgagact ccttttttct
     5581 ggcgaaatgt ccaaattcac ggaatccatc aagaagacgt acgcaatgcg ccgaaattcc
     5641 cagaagtctg gcaaactatc caaccatatt ttcaaaaaaa tcgtttagtc gttgcacata
     5701 atgctgcttt tgatacaaag gtcttagcgg gatgcttaga ttattatcat cttgaacagc
     5761 ctaattatct ttctttatgt acagtgaaaa gtagccgtcg cctgtttcct gaatttccaa
     5821 atcatcgatt gaacactgtg tgcgaaaatt tgaacatcca attagatcat caccatgatg
     5881 cattggaaga tagtcgtgca tgtgcggaaa tcctgcttta tcaagaaaaa aaattcggga
     5941 cagatccatt gaaaaaactt gtgactataa agtaaaagaa tacttatgaa acacacaaag
     6001 aggtcgtgag cctgccgttt cactccgagt cacaaggagc aatttcaaaa aatagcttct
     6061 catgtttatt aaatattgtg actggtgacc gaggagctgg caggagaaca ccgtttattg
     6121 gagaggttgt gaaaaagctg ttctgcatca agtaataaga acagccaaac aaaaatagct
     6181 tctcatattt ttcatttggt tggacttatt accgcagatg caagcttttg gacaccgttt
     6241 accaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa cggcaaaata
     6301 gttcctcata ttttgccgtt ttttgagcta ataccgaagg tcagctgatt gaacaccgtt
     6361 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
     6421 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
     6481 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
     6541 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
     6601 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
     6661 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
     6721 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
     6781 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
     6841 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
     6901 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
     6961 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
     7021 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
     7081 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
     7141 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
     7201 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
     7261 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
     7321 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     7381 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     7441 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     7501 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     7561 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     7621 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     7681 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     7741 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     7801 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     7861 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     7921 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     7981 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     8041 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     8101 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     8161 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     8221 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     8281 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     8341 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     8401 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     8461 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     8521 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     8581 atatgtatta tcatacacta ttccagaaaa aaataacagt ttattttatc tgtatcagtc
     8641 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     8701 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     8761 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     8821 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     8881 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     8941 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     9001 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     9061 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     9121 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     9181 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     9241 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     9301 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     9361 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     9421 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     9481 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     9541 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     9601 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     9661 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     9721 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     9781 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     9841 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     9901 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     9961 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
    10021 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
    10081 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
    10141 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
    10201 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
    10261 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
    10321 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
    10381 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
    10441 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
    10501 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
    10561 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
    10621 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
    10681 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
    10741 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
    10801 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
    10861 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
    10921 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
    10981 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
    11041 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
    11101 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
    11161 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
    11221 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
    11281 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
    11341 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
    11401 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
    11461 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
    11521 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
    11581 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
    11641 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
    11701 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
    11761 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
    11821 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
    11881 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
    11941 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
    12001 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
    12061 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
    12121 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
    12181 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
    12241 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
    12301 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
    12361 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
    12421 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
    12481 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
    12541 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
    12601 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
    12661 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
    12721 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
    12781 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
    12841 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
    12901 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
    12961 taggtccccc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
    13021 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
    13081 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
    13141 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
    13201 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
    13261 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
    13321 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
    13381 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
    13441 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
    13501 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
    13561 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
    13621 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
    13681 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
    13741 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
    13801 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
    13861 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
    13921 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
    13981 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
    14041 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
    14101 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
    14161 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
    14221 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
    14281 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
    14341 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
    14401 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
    14461 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
    14521 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
    14581 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
    14641 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
    14701 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
    14761 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
    14821 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
    14881 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
    14941 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
    15001 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
    15061 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
    15121 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
    15181 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
    15241 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
    15301 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
    15361 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
    15421 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
    15481 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
    15541 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
    15601 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
    15661 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
    15721 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
    15781 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
    15841 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
    15901 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
    15961 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
    16021 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
    16081 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
    16141 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
    16201 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
    16261 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
    16321 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    16381 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    16441 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    16501 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    16561 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    16621 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    16681 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    16741 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    16801 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    16861 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    16921 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    16981 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    17041 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    17101 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    17161 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    17221 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    17281 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    17341 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    17401 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    17461 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    17521 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    17581 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    17641 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    17701 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    17761 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    17821 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    17881 ccgagaataa caatcaagac gcc
//
LOCUS       DADVXK010000054        17590 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.054, whole genome shotgun sequence.
ACCESSION   DADVXK010000054 DADVXK010000000
VERSION     DADVXK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.054"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="KB909_001719"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="KB909_001719"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBB6837742.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="KB909_001720"
     CDS             complement(2260..2511)
                     /locus_tag="KB909_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBB6837743.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="KB909_001721"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="KB909_001721"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBB6837744.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="KB909_001722"
     CDS             3461..3679
                     /locus_tag="KB909_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837745.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="KB909_001723"
     CDS             complement(3968..4480)
                     /locus_tag="KB909_001723"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6837746.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="KB909_001724"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="KB909_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBB6837747.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="KB909_001725"
     CDS             complement(6933..7376)
                     /locus_tag="KB909_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBB6837748.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="KB909_001726"
     CDS             complement(7377..8165)
                     /locus_tag="KB909_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6837749.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="KB909_001727"
     CDS             complement(8162..9103)
                     /locus_tag="KB909_001727"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBB6837750.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="KB909_001728"
     CDS             complement(9280..9867)
                     /locus_tag="KB909_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBB6837751.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="KB909_001729"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="KB909_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBB6837752.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="KB909_001730"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="KB909_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6837753.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="KB909_001731"
     CDS             complement(12784..13719)
                     /locus_tag="KB909_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6837754.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13905..14864
                     /locus_tag="KB909_001732"
     CDS             13905..14864
                     /locus_tag="KB909_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBB6837755.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14950..16044)
                     /locus_tag="KB909_001733"
     CDS             complement(14950..16044)
                     /locus_tag="KB909_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6837756.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16233..16994
                     /locus_tag="KB909_001734"
     CDS             16233..16994
                     /locus_tag="KB909_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6837757.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17109..17549)
                     /gene="fabZ"
                     /locus_tag="KB909_001735"
     CDS             complement(17109..17549)
                     /gene="fabZ"
                     /locus_tag="KB909_001735"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6837758.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT         5053 a         3831 c         3085 g         5621 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc ataaatgacc tacaaacatc
    13921 ttaccataga cgaactgaca atgatagaat catattatct tcaacataat aagccggttg
    13981 aaatcgctaa ccgaatggga cgtgctatac aaactattta taatgtagtc aataagttca
    14041 agcaaggcaa gactgctctt gattattggc accagtataa agaaaataag aaaaaatgtg
    14101 gtagaaaagt cattcaatta cctgctcatg aagtagatta cattaaagag aaagtcactc
    14161 ttggttggac gcctgacgtc attatcgggc gaaaagaaag gtctgtttca tgcggtatga
    14221 gaacacttta tcgtttattt tctaaaggaa tatttgatat tgacacacta ccgatgaaag
    14281 gtaaaagaaa acccaatggc catcaggaaa aacggggaaa acaacagtat cagcgctcaa
    14341 tccatgatcg acctgataat tatcctgatt tcaattctga gtttggtcac cttgaaggtg
    14401 atacgatcgt tggcattcat cataaaagtg ccgtcattac tttagttgaa agattatcta
    14461 aagtcattat cacgattaaa cccaacggcc gtaaggcatt agatattgaa actgccctta
    14521 atcaatggtt ttctcgcttc cctaaaaact tctttaaatc tattacgttt gactgtggaa
    14581 aagaattttc taactggaaa gccattagta accaacatga tattgatata tattttgcgg
    14641 accctggaac accttctcaa cgcccattaa acgagaattc taacgggatt ctgcgtcgta
    14701 atggactgcc gaaatcaatg gattttagaa aagtgaatca gacatttatt tccagtgtca
    14761 gcaatcaacg taatcatatt ccaagaaaat cattgaatta cagaacacca atcgaaatat
    14821 ttttgagcta tgtacaagaa gcattttatt ctagcttaat ttgacaaatc ataacctata
    14881 aaaaaacaaa ataaaaaagc agaaataact ggctatttct agcggattat ttctgcaata
    14941 actaattatc tattttttat tttcaattaa tttaaagctt gaccatggtt tcaaaaagtc
    15001 aaggaggaat aattcgtcat cggagattct tcctacaaca ttgacacgtc cgtcgttttt
    15061 catatccttc aaggcgattt gtgtttctcc tttgtattga ccgtaccctt cattgtcaat
    15121 cagtacatcc ccatgatgca tatctcgcgt attatgaggc gggaaatctt tatctttgta
    15181 gtatacacga gtcatcgttg aacgaaggat atattctgag cgatcccctc gataactatg
    15241 aaggttatca aacaagcaga ttcgttcgtt ttctgtaata ccttcttccg tatctacttt
    15301 caatgttgga taatccgcgt taaatgcttc tgccatttct ttcaattctt cttcacttgc
    15361 gtacgcattt ccaatagaaa tatcatcaat caatcctgta aggattaaat gcttcacttg
    15421 tgtcgcaatt tcaagatctc ggtggtcttc cagcgtgcac aagccatctt gcgtaggcca
    15481 agggccaaac tcagcagatt gcgaattgac gaatgccatc gtattcaaat tatattttct
    15541 gaatttttct gaacaaaaaa caaagtgttc gtatcctaaa ccagagtatc gatgaggata
    15601 aaaattatga gaacctaata aattatccgt gtttggcgaa taactcatga tgttgtcaac
    15661 gtaattcgtg cccgaactca tattgatctc gattttgata ccaaaaggat tgcgcgtcat
    15721 ttttgcttct tctgctcctg tgaatccgat atctaagcgg accccgtagg cacccatctt
    15781 atggaaaaaa gataagtcat cgtaagaaat ctccaactgt tcaaataacg ctggattgat
    15841 atcaaccatt acttccatgc ctaggctatt cgcgtaatca actacttctt taaattctga
    15901 aagaactttt tctttatcat cattgatctg cagcaaactg gtaaaaaccc gtttataccc
    15961 atacttatga gctaaatcca agtacgcttt gtccttttca aatgttgacc gttctggata
    16021 aatcgagatt cctaattttc ccatattacc atttcctcct gcatcttttc gtttttgtat
    16081 ccacttacat tatagcaaac acaaagtaaa tggtctacac cttttctttt tcttttaaaa
    16141 taaatgataa attccaataa tttaagtagg tattttccct ctattttgtt atcattaaag
    16201 ataacaaaat agtaaattgg aaaggaacag ttatgaagaa aaataaagtt attttaagta
    16261 ttagtttagc agcagcattg ctgtttgctg ctggttgttc tgcaaacaac acgacttctt
    16321 ctagttcgtc tacagaaagt tcaaaaagta catctactgc ggaaagcacg actgccagta
    16381 gcgtcgattt gaacgcattg gaattaccac aattgacgaa agatgtcgcc gaaaatgaag
    16441 atctggtcga aatggtgacg aataaaggca caatcaaaat caaattattt cccgaacacg
    16501 caccaaaagc ggttgaaaac tttatgacac atgcaaaaga cggttactac aacggactga
    16561 ctttccatcg cgtcatcaaa gatttcatga tccaaggtgg cgatcctaaa ggcgatggca
    16621 ctggagggga aagcatttgg ggagaaggat ttgaaacaga gatcaacaac cacctttata
    16681 atataagagg tgcgttatct atggctcgct cacaagatcc taacagtaac ggcagccagt
    16741 tctttatcgt tcaaaataca gatgatatgc atgatggtct tttaaaagac gactatcctc
    16801 aagcaatcat cgacgcttat aaaaacggcg gttatccttc actagatggc cattatactg
    16861 tcttcggcca agtgattgaa ggaatggatg tcgtggatgc tattgcaaat atcgaaacag
    16921 atagttcaga caaaccaaaa gaagaagtaa aaatcgataa aatcaatata ctgcaagaag
    16981 caaaacaaaa ataaaaaaat aacgtctgaa tcctgcatag atgacaacgt atgctaggat
    17041 tcaggcgtct tctttttaca taaaaagcaa gtaagcttcc ttttgttttg ctatatcagg
    17101 ttttatagtc aagcattttg gttgacgatg aacgtgaact cgcactcaca gactttttta
    17161 tcatctacat atgctgcaga taacgctgta ccgactgatc ccttcatttt ggtgatttca
    17221 aaatgacatt tcagcacatc tcctggaaca actttttgac ggaatttggc cttattgatc
    17281 ccaccgatat aagctctttt tcctagaaac tcttctgatt ttaggataag tatcgaacct
    17341 gcttgtgcca gtgtttctag aatcaacgca cccggcatca ctggattgtc aggaaagtga
    17401 ccttggaaaa aatcttcatt gattgttaca ttttttgtcg caacgatctt ttttcctggt
    17461 tctaaagtat ctacataatc aatataacaa ataggataac gattaggaat caattccatt
    17521 acttcagtag cagataatac gtaagacata attaaactcc ttctttcagg caattgccat
    17581 tttcattact
//
LOCUS       DADVXK010000055        17234 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.055, whole genome shotgun sequence.
ACCESSION   DADVXK010000055 DADVXK010000000
VERSION     DADVXK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.055"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            24..461
                     /locus_tag="KB909_001736"
     CDS             24..461
                     /locus_tag="KB909_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837759.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            556..1440
                     /locus_tag="KB909_001737"
     CDS             556..1440
                     /locus_tag="KB909_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6837760.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1664..4831
                     /locus_tag="KB909_001738"
     CDS             1664..4831
                     /locus_tag="KB909_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837761.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4851..5396
                     /locus_tag="KB909_001739"
     CDS             4851..5396
                     /locus_tag="KB909_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBB6837762.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            5424..5879
                     /locus_tag="KB909_001740"
     CDS             5424..5879
                     /locus_tag="KB909_001740"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBB6837763.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            5876..6634
                     /locus_tag="KB909_001741"
     CDS             5876..6634
                     /locus_tag="KB909_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6837764.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(6720..7460)
                     /locus_tag="KB909_001742"
     CDS             complement(6720..7460)
                     /locus_tag="KB909_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6837765.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            7521..8774
                     /locus_tag="KB909_001743"
     CDS             7521..8774
                     /locus_tag="KB909_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6837766.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            9096..9323
                     /locus_tag="KB909_001744"
     CDS             9096..9323
                     /locus_tag="KB909_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6837767.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            9446..9772
                     /locus_tag="KB909_001745"
     CDS             9446..9772
                     /locus_tag="KB909_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6837768.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            9840..10553
                     /locus_tag="KB909_001746"
     CDS             9840..10553
                     /locus_tag="KB909_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6837769.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            10863..11713
                     /locus_tag="KB909_001747"
                     /pseudo
     CDS             10863..11713
                     /locus_tag="KB909_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            11834..13699
                     /locus_tag="KB909_001748"
     CDS             11834..13699
                     /locus_tag="KB909_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6837770.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            13747..15156
                     /locus_tag="KB909_001749"
     CDS             13747..15156
                     /locus_tag="KB909_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBB6837771.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            15264..15965
                     /locus_tag="KB909_001750"
     CDS             15264..15965
                     /locus_tag="KB909_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6837772.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            16124..16603
                     /locus_tag="KB909_001751"
                     /pseudo
     CDS             16124..16603
                     /locus_tag="KB909_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
BASE COUNT         5751 a         2896 c         3714 g         4873 t
ORIGIN      
        1 aaaatgcacg tagaagtaga taaatggagt ggttttgcaa atttctttta tttctagaag
       61 ttattcacgt atacggattt gtttttctca caaataaaaa ggcaggaagt acaatggatc
      121 atttgtatat aaaatatatt catcaatttt ccgttttggt gttaggcaca ctaattatag
      181 cggggattgt cgcatttatt attcaaggcc gtgacatatt aacagtacat caagagtttt
      241 tcagttatgc atttggtatt cctctgatcg ctataaggtc tgataacaaa aagtggaaga
      301 aacgctatta cattctcttg ctatttttgt gtttttatct gccacctaag atttttactt
      361 tattaggtat acaatgccta tcattttctt ttatttccta tatcattgtt ttaattttcc
      421 tcagtttcat agtatggatg ttttatcttg tcaaaaaata aatgaatgtt tcatgaacag
      481 tacttcatca cagcctaatt tttttcttta tgctatcgtt atattaaaga aatcaatcag
      541 aagggaaaga aagtgatgaa aaaagtttta ttagtggtaa accccagttc aggcggtgaa
      601 caagcaaagg aatttgagca attagcgata gcaaaattgg aatcggtgtt tgatgaagtg
      661 gtcgtcttgc atacaaaaaa agcaggggat gcaaaaaact ttactcgcga agcggctacg
      721 gaagggtatc atagtgtgtt tgtcatgggc ggagatggaa cagtcaacga aggaatcagt
      781 ggaatcgctg aacaagaaca tcggccaaat ttcggatttt tcccattggg tacggtgaat
      841 gacttggctc gagcattagg gataccgcta gaacctgagg aagcgatcaa tcatttttcg
      901 attgaatcag tcaagccatt ggatattgga aaaataaatg acgactattt tatgaatgtc
      961 gtcgcaattg gctctatccc tgaatcaatc aatgatgtag atgcggagaa gaagacgaaa
     1021 tttggaaaac tagcttattt catgtcagga atcaaacagt tagcttccac acaatcctac
     1081 tcgtttcacg tagaagttga tggaaagaag gaagaaattg agagcagtac cttgctgata
     1141 ggactaacta actcagtcgg cggttttgaa acattacttc caaatgcaaa agtggatgat
     1201 ggtaagctcc atttggttta tttaaaagat tcttctttga tcgatacgct taaaacattg
     1261 ccagacctat taaaaggagt agatgaatct acgaaaaatc tagcctacct tacttgtgag
     1321 caattagttg tgtcattagc tgatgaggaa gaattgacga cgaatgttga tggagatgaa
     1381 ggggataaat tacctgtgac aatcaaagta ttgccctcac atttacaggt ttattgttaa
     1441 aatggaggtt gtgaccgagg agttggcggg agaacaccgc ttgttcggga taagggactg
     1501 tgacaagact tttgtcacag cctttttttt gtacaaaaaa gaaatttaca cctaatagaa
     1561 aaatttttcc ataaaaatac atattttaaa tatgaaagta caattggaaa tagattaaaa
     1621 cgataaaata aaattgtcaa aacgtcagag aggatggtgg agaatgaatc aatgtgtaaa
     1681 aaagctgatt gcgtcgattt tgtttgtctt ccctctcttg atggtgacat ccgtttttgc
     1741 cgatgtagag aaaacaaacg aatcaacgca atcagagaat caaagttttg acaagactac
     1801 tttttcagaa gaatcgatta cttctgaaac tacagaatct caaagtgagg cttctactaa
     1861 taaaaggcaa gaagaaaata agacaagtga gacctcagaa gtagctgaac aaacgtctga
     1921 tagcagtgaa gcggcactgg caagagctgt ttcagcggat gggtacagcg aagctgccac
     1981 aacagaagaa ctggcgcagc ttctcgcaga cgaatcagta actaagatcc gactgattca
     2041 gcctttgact ttagacaggg aattagagat caaacgagat atcgttattg attttggtgg
     2101 attcgctcac aatttcggca cacaccatat ttatatcaat gagatacctc agtcgatcga
     2161 gttccagaat tttaaaggaa cagctgcaca tccaggtgga ttgacaccaa atatcgatgg
     2221 aaatgccatt atcattgctt atatgaccga tttttgggga agcagatatc attttacggg
     2281 agaaataaaa tttaccggga cacttgattt gtatgatggg tccaaattag gactgattta
     2341 cgctcctcgt gcaactgtca cattagatgg tgtttccggt gtgttggatg tccaaccagt
     2401 gaaggaagga ctgaatgccg ctccgggtaa agcctatttt tgtagaagct atcaattgaa
     2461 tgtgatcaat ggtagtcaac tttatggacc gtatctaggg aaattctacg gttttctaga
     2521 ttcaggagat gagactggta gtggaaaaac agcgccagga atccatatct taagcggttc
     2581 aaaggtctct cttgattatg atcgggcaga tggcgttagc gatgaaggag aggcagtcga
     2641 tacgctacct ggtaatgtca tgtttgaagt cagtggttcg ggaagcgaat tttcggtaaa
     2701 tacaaagatc aatattacca atgacaacaa tcgcggaatc atccaaatga gaggttcagg
     2761 atcgaaagtc actgtatcga atggtgggaa aatcaccatc aatacagcaa ctacgggcgg
     2821 atttcgcttg caaggagatt ctagtcaaat ccatgtatca agtggtggac aaatctcggt
     2881 caaaatggct ggagatgacg atcaacccgg gaacaatggg atgcgttttg taggaaaagg
     2941 cctttctttg atcgtagaag gagccggatc agttatcgac atcgataagc agagtgggcg
     3001 ttccagcgca gttcgttttg agaatggtac gcaaaagctg acagtaacca atggaggctc
     3061 attgagggta agaaatacag gtgatggcaa atcttacgtg aacagactca atcaaggaaa
     3121 tcaagcgatc caattttatg acgcttctgg ttttctagaa agtccaggtt cagctgattt
     3181 tacagtcact ggagaaaaat caaatatcga tatacgcgca gattccggag caactgtaga
     3241 tacaactgga gatattgatt taaattttac ggcaggtgaa aaaacttatt tagtcatggt
     3301 cgggaaaaca ggggaagata agaccggcat catcagtggg gatgtgttga atgtggactt
     3361 agaatctcct acctattttg atttccaaaa caaacggatt ggaagcgaga ccaatggcat
     3421 aggcggctgg gtattccaag gaaatggaga ttcttcttta aagatcgccc attcagaaat
     3481 cgctttatgg cgaaaaacag gcgcaacatt cgataacttt gaaaaagacc cggattattt
     3541 ttctgatatg acagacttat cgatcaatgg gaccgactta ggcaatttcg tatcaagccc
     3601 tagtgcaggt ttaacaaatg aatttgctca gacaggtgcc ggaatgaaaa attataatcg
     3661 aatcagtgcc aataatcagc tcccgatgat tgaatcctta agagtgccaa cgaatgcaga
     3721 taaaaaaatc tatgggcatg tcgttgttcc cgaaggtgtc gaggcaaagc caagagatgc
     3781 ttggacaggc gaagtagaag tgactttacg tattacttac gcagatacga cgaaatcatc
     3841 tgtagaaatt actgctctca cgcaaggaca aacagatgaa aatgaagggg caggatataa
     3901 cccatgggga gaaggcgaac aaggcggctt gttcgaagtt caagtaccca atgatgagag
     3961 attaaaaacg gaggatcaag tgcaagttgt tgctgctaaa aaagtaagag gtggccaaga
     4021 agtgacagaa ctggactctg ccaaaacgac agtcgatgtg attcctcctg aacctgctaa
     4081 tttaagtacc acattgatca atgcagcttc tcgcacgatc acaggtacag gtgaagcagg
     4141 agccttggtt tcattgaaaa aaaatcaagc tgttttgtca gaaacaacta ttgatgatac
     4201 aggggaattt gttctttcta tcccagaaaa tcaacttttt gcaggagatg tattagaaat
     4261 tgtattaaac gaccaagcag gagaagctac tgctaagggt gtgcagaaca agccaagtac
     4321 caacgatgaa attgggaatc acaatccaag tgatacgcca gttgtttatc atgatgcccc
     4381 gccttttgca cctgctacga agatcgtagt agaaggtggt ctctcatttc ttgccccttc
     4441 caaactcgat tttggtcaga tcaaagcaac tggtttgaca caagaagcat ttggccaaat
     4501 ggatatacag gaaaaattat ggatttatga tcagcgagaa acgaaaaatc cgtggatctt
     4561 aacgataaaa ttatctcagc ctttcacaaa tgatgcagga ttttctatgc aggatgtcct
     4621 atatttcaag aaaggagagg agtatcaatt agtgaatgaa gaagaactgg aaattgtcag
     4681 aggacaaaat tcaacgaatg tgcaagcaga ttattcagaa tatttaaata acggtcgggc
     4741 gtttaaactt gtcttaacca aagaaaatca gatagctggt aattactcag cagagataac
     4801 atggacatta gcagatgcgc cgacagaata aagatcaagg aggatgattg atgaatcgaa
     4861 tatggaataa aagtcatcga aacaactgct ctttacttat gatccttctc cttggattca
     4921 tcctttggca gacacctgtc catgcctccg aattcaattt tgcggtagat tttgaattac
     4981 cggctaatca gattgataag aacaaaacat atataaatgt aaggatggag cctgggaaaa
     5041 cacaggaaat cccctacacg gtctttaacc gaacagataa atcagtaaca gttgagacat
     5101 tgatccactc cgctacgacg aattcaaacg gtgtgatcga atatggagaa tcaaaaagta
     5161 aatttgatga aacattaagt tatgatatga aaaacttagc aaaaacagtg ggagaaataa
     5221 ctgttcctcc tcaaagtgcg gtcactgaga cactttcact gaaagcgcca gaaaaagagc
     5281 tggctggtgt ggtcgcagga gggatcacgt ttcaagaaaa aaaagagaac gtttctaaca
     5341 aaagtacagt tggtgtcgtc aatcagtttt ctcaagtgaa agcaatcttg atttgaaata
     5401 gcgaaaaaga gtcttcccca gatttgaaat taaaaaaagc ttatgcggat caaagcgatg
     5461 gaagaaatgt gattaaggcg aatcttcaaa atccaaatgc ttcttatatg ttcggcttga
     5521 ctacatcggt tgaaatctac aaaaaagaaa caaaagagcc ttacctttca ataaaaaaag
     5581 aaaaaataga tgtagcaccc aatacaaatt ttgatttact tgtcccatta gaaggaaaaa
     5641 aattagctcc gggacattat caagcggttg tgaagggtgc ttggaaagaa aaacgctgga
     5701 atctccatac cgattttgaa ataactgatg atgcagcgga ccaattgaat gaaaaggata
     5761 ttgatttaaa aaatcagcca gaaacatttg actggcgatg gctgatactt gttggagtca
     5821 ttcttattgg cttatttgct ggattattta ttttaaaaga aagaaggaaa aagaaatgaa
     5881 aaaaacaatt gcattaagta ccgttctagc tggaagtcta ttattatgta cacaaagtgt
     5941 ttttgctgag aataagagct cagccactac agaaggaacg atttctgtga ccaaaccaga
     6001 tgctgcaaat cctgaagacg ttgttccagt tcctcctgtt gatccaaatg atcctgatac
     6061 tccttttaca cctgacgaac caaatcaggg aacatccgga ttactgacga ttgaccaagc
     6121 tccagatctt gattttggaa caatcaagtt aggtacagca aaaacagtat atgctgcatt
     6181 acaaagcgga acggacagta ctggagcaca aacacaagta cagaatttcg tacaagtaac
     6241 ggataaaagc ggaaattatg ccggttggaa attatcagtc aaacgaacag aatttattgg
     6301 tacaacatct gatacgaata aactaactgg ttcaaaggtg aaattcaaaa acgccgtgat
     6361 tcgaaatagc gcaactaata gcagtggaat gccatctacc gtttctggaa ctggcgctga
     6421 aggaatcgaa atcccagcag atcaggcagt agatctagta actgcaggag caaatgaagg
     6481 gattggcaca tggatttatt cattaggaga gaatgtggaa caagggagac aatcagtgga
     6541 attatttgtt cctgtatcca attatgctgt agacaactac gtttcaacat tcacatggtc
     6601 gttaacagat gctcctacag aagaggaagc gtaaaatcat atcaacgatt tcagggagtg
     6661 gagccgattc aaggcccact ccctgaaatc tgctatgctt acgtctcagc tcttattcat
     6721 caactcgaag cagttttttg gaagtcatgg aaacgttcct ttgtcttttc aaagatcttt
     6781 cgaccaacga gtaaggagtc accgttgaaa aattctaaca cataatgagc agaatcaatt
     6841 ttctgcaatt gcgataagtt gatacagtaa gattttaaaa gtaaaaagta agcatacttt
     6901 tctaactctg tcttcaattg ttttaaagaa gtattcacta atttatcttc tgtagttgtt
     6961 ttgaccataa cttggttttt caaacctttg atactttcaa tatataaaat ttcccgagga
     7021 tacaggacga gacttccacc tttttgatca ataaagattt tatcgacatt tacgatctgc
     7081 tgttctttcc aattgatctg ttctagcact tgacgaattt gttcagataa attcctgtct
     7141 tttctgatat atccaatcgg aaggattttc cgattgatga tctctactgc aaaattcgta
     7201 taagcggtga aaaaaacaat attactatgt gcattttttt tacgtatttg ttcggcgaca
     7261 tcaatacctg tgagtgattg cttcaagtcg atatcgataa agaaaacatc gtgattatca
     7321 atagtgccca actggatcaa ctgattgatt tgagagatag aagtgagctg cacgatattc
     7381 tcgatatgat gattgaccaa ttctctgatg atccattcgc tgtgaaactg gttatcttct
     7441 atgataaaat actttttcat atgcaggctc ctattaaaaa aatatgtgta cattttgaaa
     7501 caaaacaatg gaggaataag atggtcgcaa cagtgacact ttatttgacc tttactttga
     7561 ttttagattt aggtatctat ttattctttt cgaaacaact gctagtaaaa aacagctttg
     7621 gttgtatagc tttgatggtg gtgacacttt tacttcctat ccctaaagtg agctttcctt
     7681 acctagttgg cttattattg atgtttcttt tttattttac tacgaaaaac ctgtttatca
     7741 gctgtttgat cagtaatctt ttttttgcta tcactggact cagctttttt ctggtttttg
     7801 atctgatgga ttatttagga aagagacatc ttggaacagc aagttttttt gcactactta
     7861 tcgcatttat tttctatcta ttagtaaaaa gtatagacaa acagacgaga tttctcaact
     7921 tgctttttac ttatccaact gaacactatt ttggaggtat ttgtatttta ttaagctggg
     7981 gcgtgattta cttggtattg ggaagtgttc acttccgctc atctaattat ctgcttctat
     8041 ctcttttgtc gatagtcatc agtttttttt ctttgttttt ttccattatg ttgatcagtt
     8101 tccaagtaaa agaaagacaa catcaggaat cgcttcaact gtatcaaata aatgaagaat
     8161 attaccatca tctagaggaa ttcaaacatg attataaaag tctactgttt tcattaaaaa
     8221 ttactcttca ggaaaataaa aaagaaacgt tggaattttt agaaatatta gaagatcatt
     8281 ctgcagctat ttttgaaaaa ccgcaaatac aacagctaac aaatattgta tccccagctg
     8341 tcaggggtgt ctttttaaaa tttctagaaa aagcagaatc ggagaaaatc ccgatccaag
     8401 tagttattcc tgtcgaagtg aaaacaatcc cgattgatct ggttgttttt attcgctgtt
     8461 tatctatttt tatttctaac gcattcgatc atcgtgtagc cgatcagagt ccgattacga
     8521 tcaatctgct ggaagaaaaa gagggatcac gttttagtat agcgaacaag gcaaatccaa
     8581 cgaatttgac gctatcggag atggtcaaaa gaggaaaaac ctctaaaaaa aatggcgggt
     8641 taggtctata cagtgcgaaa aaaatgttgg atgtttacga aaatgcagaa ctaaaaatcg
     8701 aattttcaaa acagaatcac tatttttttg tagaaatgta tctggcatct agaaagagca
     8761 aatcagccta ctgacttact gtcaaaggat aagtttgagg aaagtctaca cggagataga
     8821 gacaacaaca cagcatattc aaaagaaaca gaagcgtgat gaccgttgtc acccttctgt
     8881 ttcttttgct atgtagttaa acaaagtagt tgacacttcc gctacttagt attagtacga
     8941 aagtatactt catgatacta agtagataag aagtgaaaag cggaacccac gatcgtcaaa
     9001 atgctaactg ctttgcttac accagataaa gggaagagca atatcgctta ttttaggcgt
     9061 ggagaagcaa gcaaatccct acgatcacaa aaaaaatgct gacccagcag ttaagagagt
     9121 tagaacaaga tgaaagtatc catcgaaaag cctataacca agtcccgcct aaagtagagt
     9181 actcgctcac cgaagaagga aaatcattaa gagagattct agtagcgttg tctgtttggg
     9241 aagaagaacg tatcgaaaaa caaaaagcct caagggaaga agacacgcta ctgcatacac
     9301 atggtggcta cctaaattat tgattttcta tgacatttat tttaaataaa agaaaacagg
     9361 agttttttta aaagcatcat ctatttttta tgtaaaaaaa tggtatgatt aatcaagtaa
     9421 gaagtgattg gaagaaggca agcaaatgaa tagtatggaa aaagtcaacc agtttagaga
     9481 tgaacgtaat tggcgacaat ttcataacga aaaagatttg gctatctcta tttctttgga
     9541 agcatctgaa ttgttagaac tttttcaatg gaaaacgccg gaagaagtaa aagaaacaca
     9601 attagaacga atcaaagaag aactggcaga tgtattgatc tattcataca tgatggcaga
     9661 caaccttcac ctggatctag atgagatcat tgaagaaaaa ttgatcaaaa ataatttgaa
     9721 atatcctgta gaaaaaagcg caggtgtacg aaaaaaatac acagagttgt agaaatgtgt
     9781 cattcggctg ttggaaagag caaaagaaaa acagtaaaat gagtctggag ggagagaaaa
     9841 tgaaaaaaaa aggaaaagca aaaagatggc tagtcaatat cctcttgttc ctcttgttat
     9901 tagtaggact agctttgatt ttcaatgaac agatcaagga ttattttgtc agagagacag
     9961 gagataaata tgctatagcg aatgtaacaa aagaagatct gaaaaagaat aacgataaag
    10021 atgtcagttt tgactttgat gcggtagaac caatgacgac agaaggggtc atgaggtcgc
    10081 aaatgagagg aacagatcta ccagtgattg ctagtatcgc agtcccttca gtttcaatca
    10141 atttaccggt tttcaaaggc ttggataata cgtcactact ttacggagca ggaacattat
    10201 ctccagatca agaaatggga aaaggaaatt atgccttagc aagccatcgt gcaacgaacc
    10261 ctgaattgct gtttacaccg ctagaaaatt tagagatggg tgccaagatc tatttgacag
    10321 atttagaaaa tgtgtataca tacaaaacat tttttaaaga aaaagttgct cctacagata
    10381 cccaattact gaatgaagtc gagggaaaag aaattgtcac actaattact tgtggcgaca
    10441 tggacgccgt cacgcgacta gttgtacaag gagaactgga aagtgttaca tcgataaaag
    10501 atgcgacaga tgatatgaga tctgctttca atctagagac aaaaacattt taggatactg
    10561 ggacataagt cgttacagat taaaaacagc caaaggatat gaatcgataa ggaaaaacca
    10621 atttgctgaa aaaaagagaa acgcaaagag gtgcatctct gatttggttg ttttctagat
    10681 agacttgtgt tccagttttt ttatttttta tatgaaaagg cttgcataaa taaaaattcg
    10741 atggtatgat gattttgaat aagaaatgga ttgttactgt acggcaggca aaaccagaat
    10801 tcagctaaga aacagtaggc gaattctagg tttttttatt tttcttgaga gggcgaagca
    10861 aaatgaaaat tgataaaatt ttgaataaca atgtcgtcat ttcgaaaaat ggattcgggg
    10921 aagaagtcgt ttgtatggga aaaggactag cttttcaaaa aaagattggg gacgagattt
    10981 cgccagaagc ggtccaaaaa gaatttgttt aagagattct tttgctaaaa accaattcca
    11041 gcagctgatg gctgatattc cggcagagga gatcgaatgg gtcaaacaag tagtcgaact
    11101 ggctgaagat aaactaaaag ttgaattttc gcctaatatt tatctgacat tgaccgatca
    11161 tcttcattat gcgatcacac gagcaaaaga aaatatccaa ctgcctaatc cattattatt
    11221 tgaaacaaaa aaattttatc cgaaagaata tcaagcagcg aaagaggctc ttttgttcgt
    11281 gaaacaaaag acgggtgtgg aactttctga ggatgaagcc ggttttattg cctttcattt
    11341 tgtgaatagc caacaaggaa acgaagacat gcaagtgacg atgaccgcta ccacaatggt
    11401 aagagatata ctgagtatca tcagtaaatt cttcggcatc gtgttcgatg aagaatcttt
    11461 gaattatcag cgtatcatta ctcatctgca gttttttgcc cagcgttatc tcaaagggga
    11521 aggatctgac gagcaagatg aatttctcta cgcattagtt caaggaaagt atccaaaagc
    11581 gtttcattgt gtcgaacgga tcaatgagta tcttcgacaa acgcaaaaac aggaaatggg
    11641 gatcgcagag cagatttatt taacgattca tattcaaaga gtagtaagtg agaaaaaaag
    11701 catccaatca taaggattgt tactgtatgg caggcaaaac ctggattgaa aaaataggtt
    11761 cacgaatgtt tgtgactgtt tttttcaatc tgggttttta ttttttaaat aaaaaagaaa
    11821 gaaggaaaaa acaatggata atcaagcagt tggtcgtcgt gtatgggaag cggtaggagg
    11881 acaaaagaat gtcaaaagtt tagtacattg tgctacgcgg ttgcgattca gattaaaaga
    11941 tgaatcttta gcagatacgc aaaagttaaa agaagacccg gacgtgatcc aagtcgtaca
    12001 aagtggcggt cagtatcaag tagtgattgg cagtaatgta gcagatgttt atcaatcgat
    12061 cgtggatgag gaaggtcttg cagtttcgga ggatggaaaa gaagagtcca aaaatatttt
    12121 gaatcgtctg atcgatatta tctctagtat atttacacct tttctagggg cgatggcagc
    12181 cgccggggta ttgaaaggat tcttatcatt ggcaacggtg atgggctggc tgacagctga
    12241 tagcggtact tatcaaatat tgtttgctgc agcagatggt gtctttacct tcttacctgt
    12301 catgcttgct tttacagcag ctaaaaagtt caaagccaac cagtttttag cagtagcaat
    12361 tgctatggca cttgtgtatc cagctatcac agcagttgct ggtgcgggag aagctatcag
    12421 tttctttggg atcccagtga ttctttcacc atctggttat acttcttctg tcataccaat
    12481 cattctagcc gtatgggttc aaagtaaatt agagccattc gtaaaaaaag tgattccgca
    12541 atttctgcaa atgattttag ttccgcttgt cgttttagta gtgatggttc cattaacatt
    12601 tcttgcttta ggaccaatcg ggacggttgc cggtaatgct ttaggcggtc tcttcaactc
    12661 gatttatgga tttagtccaa tcgtagcagg tctaatcatg ggaagtttat ggcaagtatt
    12721 cgtgatgttc ggcatgcatt ggggattcgt accgatcatg tttttgaata tcgaacaata
    12781 tgggtttgat gtattgatgc caatgcttct tccagccatc ttggcacaag gtggggctgc
    12841 tttagctgta gcattgcgaa caaaagatac gaaacttcga gcattaggga tttcttctac
    12901 agtgacttcg ttatttggaa tcactgaacc aactgtgtat ggtgtgacat tacctttgaa
    12961 gaaaccattc attgccgctt gtatttctgg aggtattggt ggagctatta tcggattttc
    13021 cggagtaaaa gctttctcca gcagtttggt cagcttattg acgattccga ctttcattaa
    13081 tacggtggat ggtgtagagt caaatgtgac agtagcagta atagctacag gaattgcttt
    13141 tgttcttgca ttcgtaggta cattgatttt aggatttgac gaacaaacac aagacaatca
    13201 attagaaaac aaacatgcga atgcaggaga accgattact tcagcacggc ataccttaaa
    13261 aagtccttta acgggtaaag tactgccatt gagtgaagta ccagaccaag ttttttcttc
    13321 tggcgtgatg ggaaaaggta tcgctattga tccagaagta ggagaactag ttgcacctgc
    13381 agacggagag atcacgacta tttttccaac tggacatgct gtagggatca caacgactga
    13441 cggagcggag attttgattc atatcgggat ggatacagta gaattaaatg ggaatggctt
    13501 tgagatctta gtcaaacaag gggatctcgt caaagcagga gatttattga ttcgttttga
    13561 catcgaagca attagagcag ctggctatag cgtaatcact ccagttgtca ttacgaatac
    13621 tgatgcattt gccgatatac ttgaattaga ccaaaaagag attattgcaa acgaagatgt
    13681 tctggcaatt gtaaaataag gaggaaatca ggatgcaatc acgtttttca gaaaaatttt
    13741 tatggggtgg agcaactgct gccaaatcaa ttagaagggg cttatgatcg agacggaaaa
    13801 ggactatccg ttgcagatgc tatgcctgga ggtaagcagc gctttgcgat tatcggcagt
    13861 gaagaatttg actggacgat tgatcaagaa aaatatattt acccgaatca tcgaggaatc
    13921 gatcattacg atcgtttcaa agaagatctt gccttgtttg cggaaatggg attcaaatgt
    13981 tatcgttttt cgattgcctg gacacgaatt tttccaaatg gagacgaagg tactcctaac
    14041 gaagcgggat tagaatttta tgatcagctg attgatgagt gcttaaaata tgatattgaa
    14101 cctgtgatca cgatttctca ttacgaaatg cctcttcatt tggcaaaaga atacggtggc
    14161 tggaaaaatc gaaaactgat cgacttctat gaacgatttg ctcagacagt attagagaga
    14221 tacagcagta aagtcaaata ttggatgact ttcaatgaaa tcaattcggc ctttcacttt
    14281 ccagctttaa gtcaaggatt agtaaaaagc aatggagcag gagagtacca aaatattttc
    14341 caagcatggc ataatcaatt cgttgcaagt agcaaagccg taaaaatcgg ccacgaattg
    14401 cgttcggata tccaaatcgg ctgcatgatt atctatgcaa caacttacag catcgatgcc
    14461 aatccagtca atcaggcagc aacaatgatc caaaaccaag aattcaattt tttctgcacg
    14521 gatgtccaag tacgtggaga ataccctgca tacacagcgc gtacccataa aaaatatgga
    14581 gtcgatccgg aaaaattaga gcaaacggaa aaagacttcc agttgctaaa agaatatcca
    14641 gtggactaca tcggatttag ttattatatg tctacggcaa tcaatgagac tgatccacaa
    14701 gcagcaactt cagaagggaa cttgctggga ggagtaaaaa atccgtttct tgaggcaagt
    14761 gaatggggct ggcagatcga tccagaaggg ctgagaatcg cattgaatga attatacaat
    14821 cgttaccaga aaccattatt cattgttgaa aacggtcttg gagccattga tcatatggaa
    14881 gaggatggca cgattattga tgattatcgg atcgattatt tacgtcgtca tatcgaagcg
    14941 atggctaatg cagtagcaga cggtgtagat ttgatgggct atacgccttg gggatgtatc
    15001 gatcttgtca gtgcatcaac aggagaaatg agtaaacgtt acggctttat ctatgtggat
    15061 ctagacgatg aaggaaatgg gacactgaat cgatcaaaga aaaaatcttt tgattggtat
    15121 aaagaagtaa ttgcctcaaa tggcgtaaac ttgtaattaa agcagctgaa tgaaaaagaa
    15181 cacacttctc acatgtgatt tgtgttcttt ttttattttt tatgtgctat tcttttagta
    15241 atagtaaagc aaagggtgac gttatgaaaa ggacacgtgt actatacttg gaagtcgcag
    15301 ataaaattaa agaagatatt ttctcaggaa aatatccagt cggttcgatg ttgccgacag
    15361 aaagtgaatt agaagaactg tttcaagtca gcaaaatcac tgtccgaaag gcaatcgaac
    15421 tgctggcatc agatgaatat gtcgcaaaga aaagtggtcg tgggacgacg gttctaagca
    15481 atcgtcctta caatcgatta tccaaagcgg caagctttac gcaaatcttg gagaactccc
    15541 gatatgaagt ccggaaagaa acgctggatt tgcaattggt ccatataaag aaggaagatc
    15601 ctttgttttc ctttttcggt gagcaagctg tttgttttaa gcgcttatat tatttgaaca
    15661 atcagcctta tatttatttt gttcattatc ttccacaaga aatgatgcaa ttcagcagag
    15721 aagaatttgg caaagaatct ttgtatcgtt tgctgacgaa aaaaggatat actattgact
    15781 cattttctga tgatttctcg gcagtatttt taacagaaga agaacaagga attctgaaaa
    15841 cagacgcaca gatcggcatc aaacggatac ggaaatcgtc tacgcaaatt ggggaaatga
    15901 ttgaatattc ggaggcggtc taccatacgg agctgcatcc ttaccatatt gattatgaaa
    15961 cataaataaa aaaagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa
    16021 acaaaaatag cttctcatat ttttcgtttg gttaggctta ttaccgcaga tacacggctg
    16081 tttctggatt accatttatt ctggataagg gggtgtggca cgattttcag aaggaatcta
    16141 tgaaccaatc actgtattga ttttagcttc gatggtaacc ccattcggct tgacgatcgc
    16201 ttatttctta gggaaaatca ttcgtaaaaa tatactcaat cgtcaagaaa tcgatacatt
    16261 gaagaccgct tttcctatgg ggatctgtca gatcacagag ggatgtttcc ctatcgtatt
    16321 gaacgacttg gcacgcaatg tcatagcaac gggagtcggt gggacagtag gtggcggatt
    16381 aagcatgttt tggggcgcag atagccgtat tccggcatcg ggaatgtttg cagtcgctac
    16441 gatgaccaga ccatgggcat tcattggtgc attgttagct ggttcttttg tcacaggaat
    16501 aaccatttta ttattgaaaa aaccagtaga tccgaatgca gaaatcatcc aagaagaaaa
    16561 agaggaagaa gacatatctt gggatgattt gacaattagt taggagaggc agaatggatt
    16621 acaagaaaaa agtacaatag atgtaccttg agacaggaat ggtatgaaag aatcagagtt
    16681 agaaagaatc gaatatacag attttggttt aggagcgatc gaaactgtcc agagcatcgg
    16741 caccctcctt gaaatgacga tgaaggaaaa atgagaacct ttcgttgtcg aaagggtctg
    16801 gtatacctta tgtcgaagga aaggaaacaa aaaaactttc ctgtactatt ccaaaaagga
    16861 aagaaagtta ttatacagta aaaaaagaaa ttattcttca tgctagagat cagtacacgt
    16921 tcgagcccaa tatcaaacac tagttccagg caggcgcaac aggtgcggtt atcactgaat
    16981 tttcttccag cagtgacgat tcaagtgata tttttacaaa tccagctatt tatcgttaac
    17041 aaaaagattt ttaggagaag ctgatgaaca aaaatgatca aattttgatc gtttagttcg
    17101 tcggcttttt tatttagaga aacatcattt atcagtgaaa cataacacga gaacaaaatg
    17161 attttttcgt taataaaaga aacaagtatt tgttgtttaa aataatacac gttattggca
    17221 tataggacga aatc
//
LOCUS       DADVXK010000056        16796 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.057, whole genome shotgun sequence.
ACCESSION   DADVXK010000056 DADVXK010000000
VERSION     DADVXK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.057"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            231..374
                     /locus_tag="KB909_001752"
     CDS             231..374
                     /locus_tag="KB909_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBB6837773.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            952..2535
                     /locus_tag="KB909_001753"
     CDS             952..2535
                     /locus_tag="KB909_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6837774.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(2972..4156)
                     /locus_tag="KB909_001754"
     CDS             complement(2972..4156)
                     /locus_tag="KB909_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBB6837775.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(4181..5188)
                     /locus_tag="KB909_001755"
     CDS             complement(4181..5188)
                     /locus_tag="KB909_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6837776.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(5360..5719)
                     /locus_tag="KB909_001756"
     CDS             complement(5360..5719)
                     /locus_tag="KB909_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837777.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(5691..6062)
                     /locus_tag="KB909_001757"
     CDS             complement(5691..6062)
                     /locus_tag="KB909_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBB6837778.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(6079..6381)
                     /locus_tag="KB909_001758"
     CDS             complement(6079..6381)
                     /locus_tag="KB909_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837779.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(6398..6868)
                     /locus_tag="KB909_001759"
     CDS             complement(6398..6868)
                     /locus_tag="KB909_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBB6837780.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(6843..7121)
                     /locus_tag="KB909_001760"
     CDS             complement(6843..7121)
                     /locus_tag="KB909_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBB6837781.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(7118..8167)
                     /locus_tag="KB909_001761"
     CDS             complement(7118..8167)
                     /locus_tag="KB909_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBB6837782.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(8124..9053)
                     /gene="tadA"
                     /locus_tag="KB909_001762"
     CDS             complement(8124..9053)
                     /gene="tadA"
                     /locus_tag="KB909_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6837783.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            9185..10939
                     /gene="ade"
                     /locus_tag="KB909_001763"
     CDS             9185..10939
                     /gene="ade"
                     /locus_tag="KB909_001763"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBB6837784.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(11037..11699)
                     /gene="trmB"
                     /locus_tag="KB909_001764"
     CDS             complement(11037..11699)
                     /gene="trmB"
                     /locus_tag="KB909_001764"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBB6837785.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(11769..12551)
                     /locus_tag="KB909_001765"
     CDS             complement(11769..12551)
                     /locus_tag="KB909_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBB6837786.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(12755..13966)
                     /locus_tag="KB909_001766"
     CDS             complement(12755..13966)
                     /locus_tag="KB909_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837787.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(13959..14696)
                     /locus_tag="KB909_001767"
     CDS             complement(13959..14696)
                     /locus_tag="KB909_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837788.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            14834..15268
                     /locus_tag="KB909_001768"
     CDS             14834..15268
                     /locus_tag="KB909_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBB6837789.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            15261..15605
                     /locus_tag="KB909_001769"
     CDS             15261..15605
                     /locus_tag="KB909_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6837790.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            15785..16795
                     /locus_tag="KB909_001770"
     CDS             15785..16795
                     /locus_tag="KB909_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6837791.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
BASE COUNT         5363 a         3434 c         2953 g         5046 t
ORIGIN      
        1 aaaccatatc cctagaaaat cactaaatta ccaaacacca ttagaagttt ttttgagtta
       61 cgtaaatgga aagttttgtc tcgcttaatt tgacaaataa tatgtttaaa ataaagggaa
      121 aacagtcaat gagttcaagt aaaataaaaa aaagtgaaca ccagggcgat tagtcgccct
      181 ggtgtggttt aaaacgacct aagcatgcca aagcttattg gttcgtcaat gtggaagttt
      241 ccgatgaatc tgatacgaaa aaatatgaag tatcgatggc ggataccgat tttatcgcca
      301 aactaaaatt ttatttcggg ttcgggtacc gcgagaaggc aagtgctaca ttcggtaaat
      361 cattcaagaa ttgatgaaag gctaccgctt gccattgcaa ccacaacgat actcctgaac
      421 gcgatgttgg tgagatttcc aaagagaaga gctgtttaat gcaacggtat taagcaaatg
      481 gcaaaaggaa gtcatgtaga caaagttttt tatcaaacac catatgattt cgcctgaacg
      541 ctggtttagc tcagaataca atgatgtggt ccacgagaca ttaccctcag tcagataaaa
      601 aaagctctct gacagaatta cacatcgata aatattaagt aaatgtcagc gctagttgaa
      661 ctttctgaca ctttcaggta cactggaaaa gacaactaca cgaaggaggg aaaatactat
      721 gatgcgcatg actaaaataa caagtaatga aaattaccaa cgataccata tcgcatttag
      781 ccatgcaatt ggttttacag ttgctgttga cgggacaagt ttgtccaaaa cagttgaatt
      841 cacgtaaaat caatggccat ctcaaggtat ttttctcatg ataatctgag tttaaataac
      901 acaggccatg gataaccatg gcctttttga gtggtctcaa ggagagagat catgatcata
      961 caagcaattt ctattaaaaa aacaatcggc gggaatccat tatttgagga tttatcctgt
     1021 caaattgaag ctggtgaaaa aattgtctta gtcggtatca acggaactgg caaatcaacc
     1081 tttttacaaa tcttgaccgg cagagaaggt gtcgacagcg gtgttatcag tcgcaaaaaa
     1141 ggcttaaaga tcgggacggt cgaacaagaa cttacagttt ccgaagcgac cgtcaaccac
     1201 tacttgctcc attctgccgc tgagatacag gacctcaaac agcaaatgag tcgctacgaa
     1261 gcattgatga cagaaccaga tacaaactta gagaagtgtc tggcccgtta cggtgagctg
     1321 cagcatcgct ttgaagaact aggcggttac gtattagaag accggattgc agcgatcttg
     1381 caaggcttag ggattccaca ccgtcaggaa gcacggttaa cagaacttag cggaggcgaa
     1441 cgagttaaag tcgctttagc caaaatttta gcagccgatg ccgatttact tttactcgat
     1501 gaaccgacca atcatttaga tcttaacagt attcgctggt tggaaaacta tttacagaat
     1561 acaaaaaaat cggttctggt cgtttctcat gatcggcaat ttctcgatca agtcaccaca
     1621 aaaacatggg aactggaaga aggtgcattg attgagtatc ccggaaacta cagccgtttt
     1681 cgagtcttga aagaagctcg cttggctgag ctgacaaaaa attacgaact gcagcaaaaa
     1741 gaagtccagc ggttgaaagt catgattcgt cgttttcgtc agtgggcaca tgaaggagac
     1801 aatgagtcct tcttcaaaaa agccaaagaa ctggaacgcc gcctggcgaa actgacactc
     1861 gtcaaaccgc cacctccccc gaaaaatcgg ctgcaaagct tgtctaatgg tggaaaatct
     1921 ggcaaagaag ttttcatcat tcaaaacttg caccagcagt acgctgatca agtactattc
     1981 aaagacagca gttttgcagt ctatcgtgga gatcatttag ccatcatcgg cgacaatggt
     2041 gcaggaaaat caaccttact caaattatta ctcggtgagg aaaagcctta cggtggcacc
     2101 atcaaattag gtagtagctt gcaaatcggt tatttgccgc agcagctgca gtttgccgat
     2161 cccgatagcc gtttgctggc ttacgccatc acattgactg gaaacgaaga agtcgctcga
     2221 cggcaattag ccaaaagtgg cttttatcaa agcgatgtgg gtaaacggat caaagattta
     2281 tccggtggtg aaaaaatccg tttggcgttg ctgaaactct ttttagaaaa aatcaacgtc
     2341 ctgattttgg atgaaccaac caatcacctc gacagctatg ctcgagaaga aattgaagaa
     2401 atgctgcaag actatcaagg aacgctccta gcagtcagcc atgaccgcta ctttttgcag
     2461 caacacttcc aagaagcact cgttattgat caggagcaga tcagccgcca gccgctcggc
     2521 caactgattg actaggacgt tttttcgcaa caaaaaactt gattttcata cctgtgcttt
     2581 cacgattcag gcaaagtaca ggtggaaaat caagttttta ttattcgatc aatgaatgtt
     2641 tcggatcggt tttctagcta aacataaagc gaagaataaa gtcgacagcc cacgaggctg
     2701 atctaaaaat gttttttctt tttacatatg taatgtccct tataaagatg aatgaaaata
     2761 aaatattggg attttcctga aaatcaataa ataaaatgcc agtcttttcc cttttgacca
     2821 cttttccaag caaaattccc taagaagatc ctgtaaaaaa gaagggaaat tgaagttaaa
     2881 ttaccatttt gcggtcttct ccgcaaaaaa aacacatgca agaattccct cttgcatgcg
     2941 tttcatcttt tatcctaacg aatgctttgg cttagccgcg cagacgctcc acatcacggg
     3001 caatcattag ttcctcatct gttgggatca ctaatactct tacttttgat tcttttgtag
     3061 agatatctac ttcttcacca cgcaattcat tcaacgctgg atcgatttca caaccaaacc
     3121 aagacatacc tttgatgatt tcactacgta catgtccgtc attctcgccg ataccagcag
     3181 taaagacaat tgcatcaaca ccattcatcg ttgtcacata accgccgatg tattttcgga
     3241 tgcggtccac gaaaatgtca taagctaaac gaatatgttc tttttcatag ttcttttcaa
     3301 gatcacgcat atcactagac aatcctgtta ggcctagcag accagatttc ttgttcaaaa
     3361 cattgatcat ttcatcaata tcaatctcta atttttccat taaatatggg agaacagctg
     3421 gatcgatatc acctgaacgt gtacccattg tcaccccagc taatggtgtg aatcccatag
     3481 aagtatccat ggatttacct ccatcgactg ctgtgatcga tacaccattt cctaagtggc
     3541 aagtgatgat ttttagttct tcgatcggtt tgttcaataa ttttgccgca cgttccgaca
     3601 cataacgatg acttgtgcca tggaagccat attttcttac tttgaaatct tcataataag
     3661 acaccggtaa gctatataaa taattttgct ttggcattgt tgagtggaaa gatgtatcga
     3721 atacagccac actcaaaatg tcaggtaaaa tctttttaaa cgctttgatc cccattaagt
     3781 ttgcaggatt atgcaaagga gcaaattctg ctaattcagc aatgcggtcc attactttct
     3841 catcgatcac tactgaatcc ccataagttt ctcctccgtg aacaacacgg tgccctactc
     3901 cggtgatttc atcataagag cttaaaattt gcagttcaat caactgatct aacagcattt
     3961 ttactgctac ttcgtggttt tcgatatcca tgatttgttc gaatttttga ttatcgccgt
     4021 acttgatggt aaaaatagaa tcttgtaaac cgatacgttc gacgatccct ttcgcaacta
     4081 cggtttcttc tggcatttga tataattgcc atttcaaact tgaactccca gcattgattg
     4141 caattgtttt agacatatga ctctccttct cgttgaatga ttacagagca gatgatttcc
     4201 agtttttaaa ctcgttgaaa aattccgtca ccttctctgg ttcttttaat gaagcaagtt
     4261 tcacaagcaa gacttctttt acttgttgtg cttgtggtcc ttttttctgt aagatcaaaa
     4321 tacttttttg cgattgttta ttacggaaca attcatctgg caattgaatc attccttgaa
     4381 gataaccttc ttctttaaac cattttttga tttcttcact ttgatccgtt tctaaaaatc
     4441 cactcggcat caaaaacaaa ccaaaaccat ccggcttcac atatttcatt gattgctcta
     4501 gcaataaatg atgtgcataa ctatggcctt cttcggtact tgttaaaaac tcttttgctt
     4561 tttcgtcatt cggataataa ccgattggca aatcgctgat tgcaaaatcg acaggatcta
     4621 ttaataattc ctgcaacccg tcttgatgaa agtattgaac atttgcttgt gtcaaatcac
     4681 ttgtagaagc tgcgacagcc aacaatgtat catcaatatc cacaccaatt ccttctgttt
     4741 ggtaccccgc attcgatagg tttaaaagaa ctgttaataa caagttgccc attcctgccg
     4801 caatatccag aatcttaacc ggtgcttttt tatttgtgta tagttgttca ataagaaaaa
     4861 caaataaaaa accgatacta tcaggagtga gttgatggtt cgcctgcaaa tgttctgtct
     4921 ggctgccctt caataaaagt aattgagaca gtctgcgcca ttcttctggc tcgaaagaaa
     4981 gtttcttcaa ctcttcataa agagctgtga tccgttgcgt tgtctctttt gtcggcactc
     5041 catccaccac acgtacttga taatcatcta ttaaattttc tgcattttcg acataggctt
     5101 ctaaaaagga agttcccaat gcattctgta aaagctgaat agcttccagg ttttgattaa
     5161 acccttgttc cattttttct ggtaacatgg tgcacctcat ttctagatat attataacaa
     5221 ttttttcacc tgtttaattc tatcgaacaa ttgacaaaat ttcaatcgtt ttcactgttt
     5281 tttatttgtg aaacggcaaa cattttttta ttaaaaacag tgttataaca gaaaagaggg
     5341 cgttttcacg aacattccat cattctgtac tagtatctgt atcatttttt acttcttctg
     5401 tgaaccgaaa gataaacggt gagacttcca cctctaagaa tagggactgt tgtacccact
     5461 gatatgttac agatccagtt gtgtagtaaa aaactccttc cgaactttcg gcaagcgtag
     5521 actgttccga taaagccatc tgcttcatta tttttgctat ataataattt ttgattcgta
     5581 tattaagatc cattgacaaa cggtagcttt ctaatgctgc catcaataaa aacgtacata
     5641 aaagaaataa aagcaagaca gaaaataaaa tagagccctt ataacatttt ctactgatcg
     5701 ttttttgtcc atatggcata tccatcttct ccattttcaa agtgtacata aaaagaaatt
     5761 gtgtgttctt tttccaataa ttgaagctca gtgatacttg ttaacatagg ttgatgtccg
     5821 ccggaagttc ttcttttacg tatcattgcc tgatatcttt cgatgatata ctgtttatcc
     5881 tcgatcgtgt agtgcagttg ctgatttttc acagagacat tgtgactgct cttgagttct
     5941 tcttctaatt gtgctaaaaa tattagccac tctttttgat ctttacgctg caaaaattca
     6001 cttacttgga tggtttgctg aatcaaaaga ttgaatgtga gcaatagact gctcaatatc
     6061 atcagtccaa ttagacattc aatcagcgta aatgctggaa ttacttgttt tttcaatact
     6121 gatcgcttct ttctccatat tgacaaacac tttttcgatt actccattat tatcgacaat
     6181 ttggatatcg tatgggatca tttcttccct tcgctctggt cttttgtgat acatccgctg
     6241 cgtcttgata tcttcataaa tcattcgaat aaatagcagt tcctccccac ttttcttttc
     6301 tgcctgaagc aaaaacagct ggccaaagct cactaagtag acacagacag aagcgatcat
     6361 aagcgctgta agggactcca acaaaacaaa tcctgtttta ttcaattctt tttgtatagc
     6421 gaccactccc tatctggaat tgatacgtaa tcgtccgctc tttttcttcc caataaaatt
     6481 gataagcttt tagtgaactt tcattcccgg ttctagcagc aaaagtaata gaagcatggc
     6541 gtttcaaggt aatctcatca ggaatatcta atacttccca atttatttta tctggattcg
     6601 gaacatgaaa aatgatttga ttctcttcac tattccaata aaagcctgtt tggatctgat
     6661 tcacaatagc gattttttgc gtagaataga ttcgtttttc aaattggccg aaaaattgat
     6721 agactgccaa ttcattcttc catgcagaaa atgcgagaac tggaaaagaa aggatcgttg
     6781 taagtaataa aatcagtaag agtgattcaa acaacgtata tcctgatgct aaaaccttac
     6841 cttcaaggcc gctgatagat ttctgcatgt tctcgtttga tatagccttc attcaacaat
     6901 tcctccacag taggaactct tccattattt tgaagcgcat agagctcttt ttgtgtgtct
     6961 accaactgga tgatcgcttc acgactttct tggtctacat gattcctata acgcgacaaa
     7021 ttagggacga acaacaacac taatacactg atgatcagta agacgattag catttcgatc
     7081 aatgtaaaac cgctataata agatattttt ctctttttca tggcaaaacc tcctctatgc
     7141 ttccgtaaac aggtaataaa acagcggcat aaactaataa aatcaaagcc gctacgccca
     7201 aaaaaatgat tggctgaata aaatgcatcc agtgatgaag acgtttgaaa agctgttttc
     7261 ttgtccattc gctgtaaaaa atcagttctt tacctaaact tccctttgcc tctccctgta
     7321 aaacaatttt actgaattct tctgatagaa aacgataatt ctggaactgc tcagccaatg
     7381 acatacctgc ctccaatcct tgaatcaact tagaggcaag atgctgaatc agactttctt
     7441 gtttcgtttc ctttaagcag actatgattt gccttaattc gaaaccttca tgaaaaagct
     7501 ttccaatctc tagtgacaaa taagccgatt gatacaagga atatatcggt ccaatcaata
     7561 attgtctgct tatccattca ctctgatcaa caggagacaa cttcatcaga cgatacctta
     7621 ctagtaaagc caatagagta accgctagga tgaatagtag aacataccaa tgaaagactt
     7681 gtatcagctg aataccccaa tgctcttgca tgaccattcc tgaaccaata agctgaggca
     7741 aaacgaacaa ccgcatacta aacaagatac ctagcaaaaa ggtgagcaat agcatcggat
     7801 atgcaagcag ctttttcaaa tcattgcgaa atccttcaac aagccgaaac tgtttggcaa
     7861 tttccaacaa agttgtcggc agattcccat gacgttcagc taactcgatc tgtaccagtt
     7921 gctctgctcc atatcctatt tgcgaaagta cctcactaaa cgcttgccct tcctttagct
     7981 gatgttggat atttgccaaa ataacaggtg gaaacgaacg gatcgtgagt aataaataaa
     8041 gggattcttg cagactaaaa ccagataaaa gcagttctcc catggtttgt gcaaactggt
     8101 tttgctggct tcttgttaat cctttagaat agttctgact gccaaatatt ttcctgagct
     8161 tcttcataac tttcctccca tgattttttt actgattctt cctccataaa ttgataactc
     8221 cataaaacag aaggatggtg attggcatct tccaaaagtt cttgataaat gacaccagct
     8281 aaacattcag atagctcttc ttttttcttt gtcagttcat ggattctgac caatgtacct
     8341 tcaagattgc gtgcatgtac ggttgcaaaa acccggtgcc ctgttagtgc tgctcttacc
     8401 gcagcatgtg cagttgattc atctcttatc tcgccaatga ttagcaagtc tggacgatgc
     8461 cgtaatgcga gtctcaaaag tgtatcataa gtctgtgcta ttttcggatt gatctgtagc
     8521 tgcagaaaaa acggttcttc tatctctaca ggatcttcga tagtaatcac ttgcaatttt
     8581 tcttccaaag ccaaccgata cattagagaa gtcttgcctg atccgactgg tccgctgaaa
     8641 aggtataatc cacgtctgac ggttttctgt aaaatagttg caaaatctcg agaactaaag
     8701 caacgatggg gtgtttcaaa agtaccgtat aatagccgaa tcactaaact ctctcgttga
     8761 aggtaatctc ctacagaaga caaccgcaga cgaacttcct gtttttctaa agaataagta
     8821 aatgcaccta actgagcttt tcttttttct ccgatatcca tctgtcccaa atacttaaat
     8881 cttgagatca gttgctgtcc atctgccgaa gagactttct tccagaatgt tcgttttttt
     8941 ccatagcgaa aatagatgta aaatacttct gaagctggca atatatatac gtcttgggca
     9001 tgtttggcaa aactttcact tatcatttga tccgataatc gttttatttc cattattctc
     9061 ccctccacaa aaaacatacg tctttttgat ctttttgttt caaataaaat gaatttacaa
     9121 aaaaatattg gcaaaaaccg aatttatgtt atacttataa aaatttatct tgggaggcac
     9181 tccattggaa acaacattaa ggaaatatat cgaagtagca agtaaaaaaa agcctgctga
     9241 cctagtgatc aagcatgcta agatcgtcaa cgtctttacg aaagaaatca tggaaaaaga
     9301 tgtagcaatc tgcgaaggaa tgatcgtagg aatcggtgaa tacgaaggaa aaagcgtaca
     9361 taatgctaat gggcaatatc tagtgccagg attcatcgat ggccatgtgc atatcgaaag
     9421 ctcactttta tcaccaagcg aattttcaaa agtatccttg cttcatggag ttactactgt
     9481 agtgacagat ccccatgaaa taggaaacat tgctgggagt acaggtcttg agtttatgat
     9541 agaagatgca agacaaacac tcatgaatat cttttttatg ctaccttctt gtgtacctgt
     9601 aacccctttt gagaccaatg gtgcaaattt aaatgcaaaa aaattagccc cttttttaca
     9661 aaaacccgaa gttttaggct tagctgaagt catgaactat caagcagtag caaataatga
     9721 aacagacatc ctagaaaaga tccaattgat gcaccagcat aagaaaaaaa ttgacgggca
     9781 tgcagctggt atcggcatgg aagagttaaa tgtttatcct gcagcaggta ttcggacgga
     9841 tcatgaagct acaactgcaa aagaagctaa agaacgtttg gatcttggta tgtatttaat
     9901 ggttcgagaa gggaccgttg caaaagatct ggcatcgcta ctaccggcga tcacacctga
     9961 aaattcaaga agatgcttct ttgtcaccga tgataaactg atcaatgatt tagtaaaaga
    10021 aggatcaatc gatcatatcg tccgtcaagc tattgcactt ggaatcgatc cattacaagc
    10081 cattcagatg gcaacattga atgcagcaga atgttttgat ttgaaaacac taggtgcgat
    10141 tgcccctggg tatcaagctg atttcttctt aacagacgat cttaccaagc tgccaattca
    10201 tgaagttttc tataagggaa cattagttgt tcaatctggg caactccaag accatttatt
    10261 tgctgatcat tcaaattcat atacgtgttg tctgccaaaa ctaaacgctc aaccattaaa
    10321 tccacattcg ttagagctgc ttctttcttc ttcacaagcc catgtgatcg aaattatccc
    10381 gaatagtcta gtgactaaag atttggtaga aaaagtggac cgacaaggcg aacgattcat
    10441 tccttcaatc gaaaaagacc aattaaagat tgcggtgatc gagcgtcacc atcaaacggg
    10501 aaacattgga ttaggcatag tgaaaggatt tcagctgaaa caaggagcga tagcgacaac
    10561 gattgcccat gactcgcata atctagttgt cgttgggaca aacgacgagg atatgctgta
    10621 tgctgctaat cttttgattc aaaaaggtgg cgggatgacc gttgtcaaca atcagcagga
    10681 aatagcttgt gtttctcttc ctataggcgg aatcatgaca caggaacctt tttcgatcgt
    10741 ctatgaacag ttgaatgaat taataactaa agcacatcaa ctaggagcag ctaaaacctt
    10801 tgatcctttt ttgacacttt ctttcttaac attatctgtc atacccgaat tgaagatcac
    10861 cgacaaagga ttattttcat tttctcgctt ccaattgatt ccaccttgtg gaaaaaccga
    10921 tgaaataaat acattttaaa tcaaataaat cccagaaaat acattacatc tgtaatgttc
    10981 attttctggg atttatttat ggatattaat gtttttatga aagcagaaag ttagtttcac
    11041 agacttttct ttttggtctt atcttgaaat tgagcttcta ctcgataaat acgttgacct
    11101 tttgaagaaa atttttcttc atactccgtc ataatattgc cttcaaattg actttgatgt
    11161 aaatctaacc atacctgttt gaggatcatg ccatattgag aaaaacttgc cagagaatac
    11221 tcaaacaatc cttgattatc tgttttgaaa tggatttctc catttggacg aagaatctgt
    11281 tcatctacag caagaaaagt cttatatgtc aatcgccgtt tttcatgacg tttttttggc
    11341 catggatcgg aaaaattcag atagatttga tctacttcgc tgtcagcgaa atactctgtc
    11401 aacgctgatc catccacatg tagaagtttc aggttaggaa gcggttgttc gatcaacttg
    11461 tctagtgcaa tcgaaacaac actgacctgc atttctactc caatataatt gatttcagga
    11521 tgggcttttg ccattccagt gatgaactgg cctttcccca taccaatctc aatgtggatt
    11581 ggatgatcgt tttcaaacaa ttcattccat tttcccttcc acaatgttgg atcactaatt
    11641 acaaaattcg ggtgagccgc taacatttcc gctgctcccg gacgatttcg gacacgcatt
    11701 atttatctcc attcctttcc tctaattaaa aaggtctggc caaatctccg cagagtttgg
    11761 gccaaacctc agccactgaa aattcgtttt aattgtaaaa tttcttcgtt catccgtcga
    11821 tgatcttcac gtttgcaata tctggtgatt tcttggagca aattcatggc cgcataccaa
    11881 tgaaattttt caagcatttc gtcagtcggg cgtatgccat aactgatcag ccactgattc
    11941 cagctagaca gtggcacata atttcctaaa atcgttgcaa tatccaccgc agggtctgca
    12001 aacatgattg aatcccaatc gactagatat aaataatttt tacatactaa ccaattacga
    12061 tggtttacat ctccgtgtac tactgataag ttttccttat ctattgacgg gatctgctca
    12121 cgaagaaaac gatggacaat ttgcagaaat tgatttttct ggagttcttc cggtaattct
    12181 ttttcatatt tttgcagcat cttctccggc gtcatgacac gaccaccgat acgggtcagc
    12241 atggttttaa gagaatttga atgatgtaaa tggtacaaaa catcaatcac gtcgtttctt
    12301 tgaccaatct cattaggagt cagcaagcga ccttccagcc actcttgtgc tgtcaaagta
    12361 tcgccattcc ccgttcgttt tgtccaaaca agttttggtg taattccttc ccttgaaaga
    12421 gcagccaaca tcggagtcgt gtttcgttta ataaagactt tgtcctcatc acgcatgcct
    12481 atgtatgttt ttcctgtgtc gcctttgatg ggacgtaacc gccactcttg gtctaactga
    12541 aactccatca tgcattctcc cgtcctctta ctctttgttt tgcagtactt attattctag
    12601 tcgcctgaac actacacgtc aagcacatat acgttctttt tcatttaatt gccattcaaa
    12661 aaaccagctt ttctcaaaaa aaatagaacg aacagcattc ttactgtcaa cgctctattt
    12721 ttcattctca tttttaccct acacagcttt gttttcagtc tgacatcttc ttcaaacgag
    12781 ttggtacata tagtttaaca aagagcatag taacaatcaa ataagccgct agcggaaccc
    12841 atcgctgctg cccatctaat acgactgcag caatcaaacc aaaaataacc gacgcgataa
    12901 ttaataccca tgtgagtaga tactgaatcg cctgcttctt ctgattctta tggattggat
    12961 aaagctgaac gagaaccata tagcggaact ggttcgctaa aggtaacagt tggaaaccga
    13021 tcaaatataa aaataagaaa ccgataatca gactaaaata aaagtcgact actccggcaa
    13081 tcaataaccc acctataatt actaatcgga aataaagacc actaaaatca gaacctcttg
    13141 ccaatcttct tgcaaacaag taaagataag tgttttttga ttctctttta atatgagtca
    13201 atataggatc caaatagcgt cttcttttga tctttgccgt aatttcagga acatctgtga
    13261 ataaattgat aaattgatag atctgatgca acctatgttc ttctacatgc accattttct
    13321 cccaatccaa tcctttttct tgttgcttcc acaaaaacca gtaatataga cttgcctgta
    13381 ctaatgcacc tgctattcct gcccatatta gccaataaaa tgatagaaac aaaaagatca
    13441 gagaagaaaa aaaccagcct aatttccaat aacgaataac ttgttgatct agtcgaaaca
    13501 attctgctct cttgatttgc agatgactga atttcaaact ccataatatg atcagataga
    13561 cgaaaaacat cgaaaaggat tgctccgtac taaccaccac taatggcatg gccaatccgc
    13621 atgccaatat caaaaagatc aacggaaaaa tgcaagaata gcgaaaagct cgttccaaat
    13681 aggtttgcat ttctttttct ttaggaagta aaaaaacaat atctgctgcc tctgcaaaag
    13741 tagccatctt acccacgaat aaacagagca tccaaaatac agagattatg agccctccaa
    13801 ttgcaaacgg tggctgcagg gttttcaacc aattagaata atataatccc acaccgccaa
    13861 tcaagaaaag acaaactaaa acaaaatgat cgttcaatac ataacgcata tatttcatca
    13921 ttttcttttg atgtcttgct aaacgttttt gaaaaaaact actcatgtgc ctgctccttt
    13981 gttaaagcaa tatagatttc gtccaaagaa gaatccggca gctgaaattc ttttctcaac
    14041 atctcaagag aaccgtctgc tcgtatctct ccgttatgta agaccacaaa acgatcacaa
    14101 tatttttctg cagtagctaa aatatgcgta gacatcaaaa taccggctcc ttcttttttc
    14161 atttctacca tcaattcaag caatgcattg atagctagtg gatccaagcc taaaaatggt
    14221 tcgtcgatga tatataaaga aggctcgatc aaaaaggcgc ataagatcat cactttctgt
    14281 ttcattccct ttgaaaaatt agctgggaac cagtcaagac gattagataa ccgaaaagtc
    14341 tccaacaact tttctgctct tttcattgct atatccatag gtatatcgta ggccatcgca
    14401 gtgacttcga tatgttctct caatgtcaat tcttcatata aagaaggagt ctctggaata
    14461 tacccaattt gtttgcgata ttcttccgta tttttcttta aggatagatg attgatttct
    14521 atcgttcctt ttgaagcttc cagcagaccg ataatgtgct tgatggtcgt acttttccct
    14581 gctccgttca gtccaatcaa ccctactatc tctccaggct gtacatcgaa actgatatct
    14641 tttaacacag ggagatgtcc gtacccccct gtgacatgat cgataattaa actcattctt
    14701 tttcctccgc catttatttt tatttattat accacgaaga aaatgacggt attttgtttt
    14761 tttccttaca atagctttaa cttatggtaa agttaagctg aagtatttat tctttataga
    14821 aaggatgttt tatatggaaa actgtatttt ttgcaaaatc atcaatcaag aaatcccaag
    14881 ctataaaata tatgaagacg acaaggtcta tgctttttta gacatctctc aagcaacgaa
    14941 aggacacaca ttagttgtgc ctaaacgtca tgtagcagat atttttgaat atgatcccga
    15001 acttgcagga gaggtttttt cgcgtgtgcc taagattgct caagcattgg aaaaagcttt
    15061 tccagaaatg aaaggtctta atatcttgaa taacaaccgt gaactagcct atcaatctgt
    15121 ttttcattca catatccatt tagtccctcg ctacagcaaa gaggatgatt tttctattca
    15181 ctttgtcaat catcaagata gttatggatc ggaagaacta aaagctattc aagaaacaat
    15241 cgtaaagcag gtgtcctgcg atgattaaaa actttttcaa aggactgtta tttggagctg
    15301 ctgctggcac tgtcggaggt ctgttattgg cgcccaggag cgggaatgaa acaagaaaga
    15361 aactgatcga agaattggaa gaagcaacaa ctctgacaaa tgatttaaat aacagcctga
    15421 atcattttaa aagcgcattg atcgaaacaa aagaaacagc tgaatctgtg attcctgctt
    15481 tccaagaagc aatcaaaaaa gatatcgaag attttaaatt ccaagccgaa ccacgtatca
    15541 cacaaatcaa tgaacaagta gaaaaactaa aagctgatct gccagagtat cctgaacaaa
    15601 tataataatg attattttct caacagattt aactatataa gtgagaaaag tttgcgtatt
    15661 tcctaggaat gtgatgaaat tttgaatttt gtttgaaact accacgacaa cgtttttaaa
    15721 ggaaatggga tatggtatag ttaatatata aaaataataa ctaattacag gagtgcaaat
    15781 tttaatgaaa aaaaaatcaa ttattttggc agctactagt gcgttggctg ttttaactct
    15841 agcagcttgt tcaggcgata ctaataaaga tatcgcaacg atgaaaggcg gaacgatcac
    15901 tgtatctgat ttctatgatg aagcaaaact tgaatcatcg aaccaatcct tagtacaacg
    15961 gatgatcatt tataaagtat tcaataacaa atatggcgat aaagtaaccg ataagcaagt
    16021 ggatgcagaa tacgacaaac aagcgaaatc attaggtgat acttttgaat cacaattaga
    16081 agctgctgga tatacgaaag atacttataa agaatatatt cgtaacaatt tagcttttga
    16141 agctggcttg aaagctcacg tagatattac agatgacgat ttgaaaactg cttggaaatc
    16201 tttccatcca gaagtagaag cacaaatcat caaattatca agtgaagatg aagcaaaaga
    16261 tgtgaaaaaa tcagcggatg atggagatga tttctctaaa ttagccaaag acaaatcaac
    16321 tgatacagag acaaaagaag atggcggtaa agttaaattc gactcaacga caacaactat
    16381 tcctgcagaa gtaaaagaag cagctttcaa attgaaagac ggtgagatct ccgatgttat
    16441 tactacaaca aatcctactt cttatgcgac agaatactac gttgtcaaaa tggtgaaaaa
    16501 ccaaaataaa ggcaatgaca tggataaata caaagatcaa ctaaaagata tcgctactga
    16561 aactaaacta agtgacaatg cattcacaac taaagtaatc ggtgaagaat taaaagatgc
    16621 aaatgtaaaa atcaaagatg atgcctttga aaatgtgttg agtgcattca caacaacttc
    16681 atcaagtacg aaagactcaa gtgaaactac agcttcaaca aagagttctg acacaaaatc
    16741 aactgattca acaaaagaat cttcaactga agaaacaact gattcatcaa aataaa
//
LOCUS       DADVXK010000057        16714 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.058, whole genome shotgun sequence.
ACCESSION   DADVXK010000057 DADVXK010000000
VERSION     DADVXK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.058"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(251..1462)
                     /locus_tag="KB909_001771"
     CDS             complement(251..1462)
                     /locus_tag="KB909_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6837792.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
     gene            complement(1581..2216)
                     /locus_tag="KB909_001772"
     CDS             complement(1581..2216)
                     /locus_tag="KB909_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBB6837793.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2352..3005)
                     /locus_tag="KB909_001773"
     CDS             complement(2352..3005)
                     /locus_tag="KB909_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837794.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            complement(3108..3314)
                     /locus_tag="KB909_001774"
     CDS             complement(3108..3314)
                     /locus_tag="KB909_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBB6837795.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            complement(3390..4136)
                     /locus_tag="KB909_001775"
     CDS             complement(3390..4136)
                     /locus_tag="KB909_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837796.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            4296..4520
                     /locus_tag="KB909_001776"
     CDS             4296..4520
                     /locus_tag="KB909_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBB6837797.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            4544..5305
                     /locus_tag="KB909_001777"
     CDS             4544..5305
                     /locus_tag="KB909_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBB6837798.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            5317..5574
                     /locus_tag="KB909_001778"
     CDS             5317..5574
                     /locus_tag="KB909_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837799.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            5666..5917
                     /locus_tag="KB909_001779"
     CDS             5666..5917
                     /locus_tag="KB909_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837800.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            5893..6066
                     /locus_tag="KB909_001780"
     CDS             5893..6066
                     /locus_tag="KB909_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837801.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPTEGAD"
     gene            complement(6180..6587)
                     /locus_tag="KB909_001781"
     CDS             complement(6180..6587)
                     /locus_tag="KB909_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837802.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            6748..6972
                     /locus_tag="KB909_001782"
     CDS             6748..6972
                     /locus_tag="KB909_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837803.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            6982..7176
                     /locus_tag="KB909_001783"
     CDS             6982..7176
                     /locus_tag="KB909_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837804.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            7179..8201
                     /locus_tag="KB909_001784"
     CDS             7179..8201
                     /locus_tag="KB909_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBB6837805.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            8164..8979
                     /locus_tag="KB909_001785"
     CDS             8164..8979
                     /locus_tag="KB909_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBB6837806.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            8997..9779
                     /locus_tag="KB909_001786"
     CDS             8997..9779
                     /locus_tag="KB909_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837807.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            9779..10627
                     /locus_tag="KB909_001787"
     CDS             9779..10627
                     /locus_tag="KB909_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6837808.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            10624..10866
                     /locus_tag="KB909_001788"
     CDS             10624..10866
                     /locus_tag="KB909_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837809.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            11009..11377
                     /locus_tag="KB909_001789"
     CDS             11009..11377
                     /locus_tag="KB909_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBB6837810.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            11392..11553
                     /locus_tag="KB909_001790"
     CDS             11392..11553
                     /locus_tag="KB909_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6837811.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            11550..11876
                     /locus_tag="KB909_001791"
     CDS             11550..11876
                     /locus_tag="KB909_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837812.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            11873..12688
                     /locus_tag="KB909_001792"
     CDS             11873..12688
                     /locus_tag="KB909_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBB6837813.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            12827..13138
                     /locus_tag="KB909_001793"
     CDS             12827..13138
                     /locus_tag="KB909_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6837814.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            13162..13380
                     /locus_tag="KB909_001794"
     CDS             13162..13380
                     /locus_tag="KB909_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837815.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13377..13793
                     /locus_tag="KB909_001795"
     CDS             13377..13793
                     /locus_tag="KB909_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBB6837816.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            13790..14128
                     /locus_tag="KB909_001796"
     CDS             13790..14128
                     /locus_tag="KB909_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837817.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            14125..14355
                     /locus_tag="KB909_001797"
     CDS             14125..14355
                     /locus_tag="KB909_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837818.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            14362..14565
                     /locus_tag="KB909_001798"
     CDS             14362..14565
                     /locus_tag="KB909_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6837819.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            14562..14858
                     /locus_tag="KB909_001799"
     CDS             14562..14858
                     /locus_tag="KB909_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837820.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            14935..15348
                     /locus_tag="KB909_001800"
     CDS             14935..15348
                     /locus_tag="KB909_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6837821.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15361..15747
                     /locus_tag="KB909_001801"
     CDS             15361..15747
                     /locus_tag="KB909_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837822.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            16298..16525
                     /locus_tag="KB909_001802"
     CDS             16298..16525
                     /locus_tag="KB909_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837823.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
BASE COUNT         5664 a         2726 c         3485 g         4839 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtt
      121 cgttatttaa tggtatttta aatgaagata agcgaattta cagcattttt aaatgcttat
      181 ataccgcaaa ttatcccaag tttttgtata tcctacccga gtttataccc gaaaatataa
      241 ttttttagtg ttattttata tcttttttta ataggttttc aaacgctgta gttgctgtat
      301 ctttttcttt gcgtaagaca tggccataaa cattcattgt agtattaaaa tctcggtgtc
      361 ccaatcgttt ttgaagctct tttggagtca tattaggatc gctaagcaaa taggtagctg
      421 atgtatgtct aatgtcgtga aaacgaatgt gacgcaaatt gtgacgtttg gtgaatcgtt
      481 tgaacttctt atacagataa cttccacgtg gcaaagttcc atcttgtttt gtatcaaata
      541 taaaatagtg ttttaatttc tttatattta atttccaacg aatcttttta ttctctttga
      601 ttaattcatc taacatatca aatagataag caggaccggt tactattttt tcatcatcat
      661 catttttcaa acctggcagc aaccgaatat ctgattttcc atccacttct gaaatccgct
      721 gatgaaatct tatttcttgt ttgtcaaagt caatatcttt ttcttctaaa gctgcaattt
      781 ctccttgtct tgctcctgta ataaatgcta gaacaattaa agttttaatt tctatgcttt
      841 cctcaaatgc tgcttttagc attgcatgaa tttcttcttc cgaataaggt tcttcgatat
      901 tcttttttac gcctttttct tttggtattt ttacattttc cacaggattt tctttaattg
      961 ctccgtactc atttttagcc atcaaaaata agttgttaac ggcgtataac atacgaagct
     1021 ttgtatttct tgataaaggt ttatcagagt ttctcccagg atcttttgta ttgattcttt
     1081 gagcattaac aacaattttc tttatcatgt atggtttgat atcgattaga gggataaaat
     1141 caaatttatc aagaaatcta ttctcgatca ttcgcttata gttatgataa gactttggct
     1201 ctaaattttt ttcggcctct gaaagccata tttttctata aaattcacca aaagttatat
     1261 tgaacaaatc caacgaatca tcggtcattc cttcgaattg ctctaaccag atgttcaatt
     1321 ctttatatgc cgctctttta ctacttgctt ttatagtttt gctttttctt tttgccgagc
     1381 catcaggttt gtatcctaat acagctctta gtctatatgt ttcgttgtct acttgttcta
     1441 agtatcctgt tacttctgac ataattgaat cagctctctt tctctgatac aataggtact
     1501 ataaagaagc ctatcgtata ggtttgtttc tttcttagaa cacgctcgct ttggtcggtg
     1561 gggcgtgttt tttatactaa ttagttgtga agagcaattg aaactgtctc tgttccaaag
     1621 taacctgttt gtgcttgcaa tacattattt tttgcatttg cttgggcttc agagatatca
     1681 aaaactattt taccagtttg ttgcatatca ggatttaagc tttccataaa gaaagagtta
     1741 gtgatattac cattttcatc ttgatttgcc gacatagatg cagccgaatc agcttcgaaa
     1801 gtttttccat ctgcttttaa tttgaagaat gagctatcaa cagtcacagc cttatcacct
     1861 gcatttttta cagataagtc aactactaag aaagtgtctt ttgcgttagt aggaagtaca
     1921 gatgggccaa cttgttttac tacttcaacg gagtttactt tgtattccat tttccctaca
     1981 gcaacgtcat caccgatttt ataagtcttt tcttcttttg ttgtagtttc ttttgtagtt
     2041 tctttattag tacttgttga tgttgcagta gctgaatctt tgttttcacc gccacttaga
     2101 gcaccaccaa taccaaaaaa caaaagtact attaataccc aaaaccatac ccgtttataa
     2161 aacggttttt taaccttata cattttccca tcttgaccca taactttttt tgccatttaa
     2221 atattcctca tttcttgtta taatatattt gtgatctcag aaatgaggta tgagtccgtg
     2281 ttgcagcacg ggctttttta tttataactt ttttagagat tataggcaaa atagtagggc
     2341 ataaaaatat attattgaat tccgtattta aaaaatccta attgaacttc accggaagtc
     2401 ttttgctgtg ttgtacgcaa tgcttcttct tcagacattc cattctgtac tttccatgca
     2461 acaggcgaca tcccgtattt gttaacaaaa tcagtaagtg ataaagtgtc agcgtcttgc
     2521 tgagcgcttg tttgttggtc ttctggattt tgttgagatg ctgcttgttg ttctttctga
     2581 tcttgactga taatattgcc agcatcatct gtagtcaatc cattttcata aagggccacg
     2641 ccgaaagctt cccactcttt gttggaccaa tttgcacgat cagctggagt tgactgtaaa
     2701 gtgcgttgtt tcatctgttc atatgtttct tcttgaggtg cggtttggat tgtactctga
     2761 ctggagctta taactgttgg gctaggttcc gccgtaactt ggttggagct tgtaactgtt
     2821 gaactagaat ctgttttaga tgtagatttg ctagtagatg aactggtttc agttgtttct
     2881 tttgttttac ttatttttgt ttcttggtta gaagtggcat ctgttgattc agctttttta
     2941 ttatttgaac aagctgaaag tagcagagca gtacttaaca acaacataac gctaactttt
     3001 ttcattttat actcctcttt tctttgatac aataagttgt aaagaagcct actataggtt
     3061 taacatccca cgtccacaaa ctttggtcgg tgggcgtgtt tttttgttta tagactttcg
     3121 aaaactaaag tagcttggat tctatcgcca ccaccgaaac ctttactacc accgtttgta
     3181 gtggaaatag tgtgtaatcg ataaccttta gaacactgtc tatttatagt gttttcaagt
     3241 tctgataggt tttgcgaccc ttttcctata aacttttctt ttaatacaac ttgcaataca
     3301 acgtaacttg gcatattctt ttccttcttt ctactatgat aataaatact aacccctagc
     3361 cggagcgcca actacgactg gggtattttt tagaatacga ctttcccgat tattctaatc
     3421 tgttccggtg agacgactct atcttcatat aattcgttta tagagcgtag aataatcgtt
     3481 tgactctcat aatccttata tacttcttta cacgtcacac cgtcaccatc tatttcaacg
     3541 atagcaatct caccgtcttc cacgtctggc tgttccttaa caaatacaaa ttgtccattc
     3601 ctgataactg gttccattga atcgcctata ataggaacag caaaatcagc attgtttgga
     3661 actctttcaa attcttcttc ctctacaact gtatcgccat aaactaattc agtcgggttg
     3721 gcggcagaag ctgaattttt gattgtcgga agtttttcct ttttaggaaa gtgcaccacg
     3781 tttcctcgat tttgctcttc gagttgctgt tcagcaaagt tgtagacttt tgtttgtctt
     3841 ggtttttcta attgattgta gattgtttca atggatggaa tgttattttt cttatcttct
     3901 ttaggaacat cgtaaccaag caaccatgcc tcactcacat ttaaagtttt agccaacaaa
     3961 taaagcttgt gttggtcggg cgatgactta ccattgacat attgcgatag atgacttttt
     4021 gacattttta ttccagtttc tttttgcaaa ggtaaagaca tattcaaaat atcaacttgc
     4081 tttaaatttc tttcagacat taactgatta agtcgttgct gagtcgtttg cttcatctta
     4141 tacctccttt ctgatactta ttatatacct tattgaacat aagttcaata aaaaagttaa
     4201 attaatttga acttttatgt tgacaatgtt ttatgcagga gttatacttt ggttacaaag
     4261 ttcaaaacat ttgaactaga aaggagcgaa ctaatatgag ttttgattat tctaagttgt
     4321 cgggaagaat tgttgagaaa tatggaacgc aatacaattt ttcaatcgct ttaggtttgt
     4381 cggaaagaag tttgtcatta aagttgaata accgagtacc atggaaaagc accgaacttc
     4441 aaaaagccat tgaattgcta gatattccaa aagaagaaat tggcgaatat ttttttaatt
     4501 tagaagttca aaatgtctga acttaagaaa ggaattcgaa aaaatgaaca cacaaaaatt
     4561 tgaaaacaat ctatttgaat tagaagttaa gacggaaaat ggtgaatcgt tatttaatgc
     4621 tgaaacagta gcaagaagtt tgggtttcgt ggaaacaaaa aacggtaaag aatatgttcg
     4681 gtggagaact gtcaatggat atttaaaaaa atacctttcg caagaagttg cgaaaaacga
     4741 ctttatcagt gagccaatgg tttacaaatt agcctttaaa gcaaacaacg tacttgctga
     4801 aaaattccaa gactggttag caacggaagt cctacctcaa atccgaaaac acggcatgta
     4861 cgcaacagat gaactactta acaatccaga cttgctgatt gaagtagcaa ccaaactcaa
     4921 agaagaacgc acgttacgat tgatagctga acaacgagta aatgaattac aaccgaaggc
     4981 agactattac gaccgaatct tgaacaacaa aggattagtt acagttagta cgattgctaa
     5041 gaactacggt atgagcgctg tatcgtttaa taaattgcta catgaattag gtatccagtt
     5101 caatcaaagt ggcacatggc tgctatacag taagttccaa gacaaaggat acacgcatat
     5161 tgagccattt gattatgaag ataaaaacgg caatcggcaa gtaaaaacaa ggatgaaatg
     5221 gacgcaaaaa ggacacatct tcttatatga aacattgaag aagaataatt acttaccgat
     5281 gattgaacgt gaacaaacag cataggaggt aacactatga acgaggaaat gagccaaaca
     5341 atcaaggtac aaaaaatgat agatgatcta acacatgcaa ttgatagcca agccgataaa
     5401 atcatcaagg aattgcaagg acaaaaagtt tgggatgcaa aaatgctttt caagactatc
     5461 aaatttgaaa tgaatccaac aaaaagaaag ctcgccgatg tgttggaaga aaagttggct
     5521 tccgctatca acgagcaaga attactattt gaaaccgata cttttaacag ctgatgtttt
     5581 atagatgaca gtttcatccg aatctatatc attatagatt cgattattgc aatgtacgaa
     5641 ttataaatac aggaggaaat aaccaatgga gcaactagct ttagttaacc tctcagacct
     5701 taaagcttct ttggcagaat ctgagattgc aaatgaagtg tgggatacaa agcaagctgc
     5761 ggaatattta aaaaccacaa cacgcacgct gactaaagat gccgaatctg gaaagattcc
     5821 agcagcgaaa gttggcagag agtggaggtt tagtagtatc gctttgtatc agtatctaaa
     5881 aggaggaaaa acatgggtaa attcaacaga gcactagtgt tcagcgcacc cctaatcgtc
     5941 tatgctttag gactttgggg aagcagacaa gcattaatcg gcacgatcgt ttacatggtt
     6001 tggattttta tggggcttga tgaagctgag tacagagcga aaaagcccac cgagggggct
     6061 gactaaagtg tggttctgtt tattaggtgt ttatctcgtg gccgttttag taaataacta
     6121 catgagaaaa cgtggcgaat actggtatac atcctatgcg gttctagtat gtctaatgct
     6181 tacaattttt ctaatgattt attcaaaata ggtaatactt tgtcaatcaa ataagtttca
     6241 agagattttt gttctgcatc agtgttgccg taaccaaaac ggcttaagaa aattttcata
     6301 acctctatat cttcattttg aatatatggc aggactgcat aacctgatgc ttttacagca
     6361 gatatatttt tatcagtgtt actaccaata caaataccca cattgttgag aaatgttgag
     6421 aaagttgttt gtattgtttg ggtttttgaa tcgtgttttt gtaattcaat ttctttatcc
     6481 ttcatcgatt caacatgctt attatttata accgctgtaa tcgaagggga tataagagct
     6541 actaaagcta ggataatcga aattgtgatc gtgttatcga aactcatttt ttcaccatcc
     6601 agtttttaaa ccattatatc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     6661 aaaaataaaa aaagacacga acgccagcaa gcatgatcgt gtccaaaaga aaaatctttt
     6721 aaaccattat aacacaggag gaaataaatg atctcagtta aagggttagg cgatgaaata
     6781 ttcgaagcaa tgatgagcaa agcacaacag gacatcaaag aaaaaatcat ttctgctgca
     6841 gcgcaaggac aaactagctg cactgttcga tcgagaggaa cgacaccaag ttttcttttg
     6901 gcgctagaag atgaaggcat tttgaatatc aaacgaagag atggcagcgt cagattgttt
     6961 tggcaatttt aggaggccgt gatgaaagat tttgattctt taggcgccag acagcaacca
     7021 ccaaatgaag ctagtcctgt tggagttgat tggcaagaaa atccgttata tccaggtgat
     7081 acttgctatc taacagaaga aggctatgta ccagtagacg caattctaga gtacgtccag
     7141 caacattatc caaagattga attaggagga atttaggaat ggcaaatgat ttaacacaaa
     7201 caacacaacg ttcattagat gagcaggtaa tcagtaatct tggacggtta caagaacaag
     7261 gtttagaaat gccaccagga tatagtccac aaaatgcgtt aaaaagtgct tttttcgaac
     7321 tcactaacaa tacaggagga aacttgttgc agatggctgc aaacaatcaa gaaatgaaaa
     7381 cctccatttc taatgcactt ttagacatgg ttattcaagg gttatctcca gcaaaaaaac
     7441 aatgctattt cattaaatac ggaaacaagg ttcagctaat gcgttcatat tttggaacaa
     7501 tggcggtcct tgatcgtgta actggagggg cagatattac gcctgtagtc gttcgacaag
     7561 gtgatgagtt tgaagttgca atggatggac caaacatggt tgtcaaaaag catgaaacaa
     7621 aattcgagaa tttagacaat gaaatcattg cagcctatgt agtcatcaag ttaacaaatg
     7681 gtaaagagac cacaacagtc atgacgaaaa agcaaatcga tcaaagttgg gctaagtcaa
     7741 aaatgaaaga ttctggaccg caaaaggaat ttccagaaga aatggctaaa cggacagtaa
     7801 tcaatcgggc agctaaaaca ttgatcaaca caagcaacga caacgattta ttagttcaag
     7861 ctgcaaaaga tacgttagaa aatgaatttg acaatgatcg gaaagatata acgccacaaa
     7921 cagaaaaagt ggctactctc gaacaaaaat tcttttcaaa caaaaagatt actgaaccaa
     7981 tacaaaaaga accagatccg attgtgattc cagatgatat ccaaaatgaa gtaactcgag
     8041 ttgctgatgt acctgcccat ccagaaatag agcaagcaca tttgatcgaa aatgaggata
     8101 tcaatccaat tcaagaagaa ttgatagata ttccagactt tggacgcgag gaaggtgtag
     8161 aagatgtctc agaatttgaa gacgacgagt accctttctg atgagaatta ttactccaat
     8221 gaagctgact ggcagtacat gtcaacatca caatataagt cctttttaaa atgtgaagcc
     8281 gcagccttag caaagttgaa aggcgattgg gcaccgacgt cggatcccaa agccttactc
     8341 gtaggaaact acgtacattc ttattttgaa tcaaaagaag tacatgaagc gttcaaagaa
     8401 gaaaataaat ccaaaatgtt ttctagtagg aagccgtatg gattgttgaa agatttccaa
     8461 attgctgaac aaatgattga acgacttaag caagaagaag cattcatgaa catttatcaa
     8521 ggtgagaaag aaacgatcgt gactggggaa ctatttggaa cgacatggaa aggcaagatt
     8581 gattgcttga atgttgagga tgagtatttt gttgatatca aaacaaccaa agacatgcat
     8641 gagcggaaat ggaacgaaaa ctacggatca agagaaacgt tcattgtcaa ttttggttac
     8701 gtacttcaaa tggcaatcta tcaagagctt cttttacagc aatacggaaa gatgttcatg
     8761 ccaatcatcg ctgcggtatc gaagcaaacg cctagtgagg cgaagttgat aacgattgat
     8821 caagataaga tgagctacga gctaatcatg ctaaaagaaa atattgaaag aattgtcaaa
     8881 gtgaaaaatg gcgaagaaag gccgatacct tgcggtacgt gcgagtattg tcgaggtaac
     8941 ctttcaatta ctggattcac tagcatggac gatctttaaa aggaggtgct ttgcgaatga
     9001 atctaggata catcaagtta taccgtaaag tgactagttc attcgtttgg accaattccg
     9061 atatgttcaa gctatggata ttgtgtttaa tgaaggctag tcatgaagat agaaaatttt
     9121 tatttaacgg tcaagaagta cgtttgacaa gcggacaatt cgtcacagga gcccatgcaa
     9181 tagcaaaaga gtacaacgaa ggagtcccga gtgacaaagc aattgcatgg cgaacgctat
     9241 ggagatggct taagaaattt gaaaatgaag aattattgac aatccaatcg aacgctagat
     9301 atagcgttat aacaataata aattggtctg actatcaatc gagtgacaag ccagtgacaa
     9361 gcgacggaca atcgagtgac aagccagtga caacaaacaa gaatgataag aatgataaga
     9421 atgataagaa taataatcct cgcaactctc gaaaaacacg agagtatgca gatgacgatc
     9481 caaataaaaa attggccatt cttttattaa aactcattcg aaagaatcgt agtctcaaag
     9541 aacccgattt gaacaaatgg gccaatacga ttcgtttgac gattgaagct gacaaacgaa
     9601 ctggaaaaga agttcaagac atgattgttt gggctactaa ccatgatttt tggtccacag
     9661 tcatttcatc gccaactagc ttaagaaaaa atttcgatac aatggtgggt caaaaaaata
     9721 aaagaaagca acaaaatatt tctaatgatg agttaccaga aacaggtgag gattggtaat
     9781 gaataaaaaa ctaagtgcaa tggctgcacc ttacggcgga ttaaaaacag cagatcataa
     9841 ttgcccgaaa tgtggtgatc cattgtatat ctggaaaaca aaaaataaag atggtactga
     9901 tcgatgcggt cctacatgta tcaataagat ttgtggttat cgagaaatgg taactaaaaa
     9961 tcaaaaagaa gctatccaaa aagcgaatga agcaatgaaa aaggacgcta tcaatcgaat
    10021 gcttaacagt tcaatgatta cagatgatgc catatggacc ttcgattttg atggatacaa
    10081 agtagttgat caggaaacag cacaaataaa agcgatggct caagaatggg ctaaaaaaat
    10141 tgtaaatggt agcacgattc atgcagtgat aaccggtaga acaggagccg gcaaaaccca
    10201 tctaggcgct gcagtgatta aagaagtcat gagggcatct aattataaaa ttgcttgttc
    10261 atttatcagt tatcgagaac ttttagaaca gttgaaattt gcaatgaatg atccagaagc
    10321 aagaaaagcc gtaacaggtt cgctgatggc tgagataaag aaatcagatt tcgtggtaat
    10381 cgacgatttg ggtgcagaac taggaagaat ggaagaaaac aaccaggcaa cgccttatga
    10441 tgttgatgtt ctcacatcgc tcacagaagc tcgtctaaac aaagctacga tattcacaac
    10501 caatttatca tcgaagcaat taaaacacgc gtacggtgag cgagtgttct ctcgtgtaat
    10561 gaatggaacg aaagggaaca tagctgtatt caaaacaacg acagacaaaa ggaggaatcc
    10621 agtttgacct ttgtagtgaa aaaaatgtgc tacttagata gccgagggcg aggagaagct
    10681 agtgtcgagt ttgctaaaca ccacacgact aaagaagagg ctgaccttgt tgcaagtgtt
    10741 tgtggcggcg aagtagtcga agttattaaa cccaaaagac gattttcaaa acctaagaca
    10801 aagccagtga aaaaagagtg ttgttgtccg aaaagtaacc aagcatggat gagaggtgca
    10861 aaatgacttg tttaaaatgc aacgatgaaa cagttatttg gtataagaca ttgcttggat
    10921 ggtcaacttg tgaaccttgt ccaatatgca atgaaaatgg acgacgttcg aaagaacgac
    10981 tcgaaagact aaagaaggag tatagcaaat ggcaacaaga agcaaatacg gaaacaaaaa
    11041 gcacgaagta gacggcatca cttttgattc tatcacggaa gcagagtatt acgatctagc
    11101 cttgtggcaa gcacaggcga atggttggaa agtgaagctc caggaaaggt ttgagctgat
    11161 gccgaagttt gaactagagg gcaagaagta tcgcaagatc gagtatattc ccgacttcac
    11221 attttacaaa agcggcaagc tggtcaaagt cgtagatgtt aaggggatgc agacaaaaga
    11281 ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga tattagccaa
    11341 aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat catgacaaca
    11401 gaagaagtga ttcaaatgcg aattcgaagc cttcggcgtg agattgacga tctggaacga
    11461 acaaaggcag tgatggtcaa tgaaacggct agaaaggcaa tcgatttgca catagagaat
    11521 ttaagaaggg aaatccgtag attggaggaa tgagcgtgga taaggaagcg gcttggcgaa
    11581 aattaatgtt gctgattcaa gatgagaact ggcaagaaga tgaagcagtg gttgctgaag
    11641 ttcagcgtct aggaaagatt gctaacggac gtatacgaaa aaagccagac aaaagaaaac
    11701 agcgcaaagg gaaaatcgtc gttgttttac acgaaggcaa aattttgatg caaggaacag
    11761 ctagtgagct gtctgcagaa actggatata cgcgtgggac tattcgaacg tacgcttggc
    11821 gaaatcacac cgatcgaaaa gggcacgaat ataagtattt ggaggaagaa aaatgaacga
    11881 aaacaaatta atcaaattgg gtgtagcagg agcagtaatc gtaggtattg gagttatcgg
    11941 aggatttaag ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct attcaatgaa
    12001 cggcggtatc aaagatgaag cactgacgca aggtgtgaaa tttgtaggga ttgacaaagt
    12061 gatccaatat ccaattcgct tgcaaactat ccaatcaaaa aatatttcag tatctacaag
    12121 cgacggcaaa aagacaacga ttgatatcaa atatgactac aaagttgatt caactaaagc
    12181 agcaaaaatg tacaaggaat ttgggaatat cacttcggaa gatatcgaaa gtggatggtt
    12241 aaaatctaag cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc tgcttgatgt
    12301 cctttcagga gattcctcta aagttgaagc tgaggtatta acgaactttg ctaaatcagt
    12361 tgaatctaaa gggtttgaag tcgaagacgt aacacttggt gttccagatg tcgataaaga
    12421 aacacaaaaa tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa aagcgaagct
    12481 agacgcagaa actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa caaaagctgc
    12541 agaagcagag gcagaatcta atcgcaaagt cgccgaatca gtaacagaca atttgattcg
    12601 ttatgaagaa gctcaagctc gcaaaaagca tggatgggta acagtaaatg gagcagatac
    12661 tgtagttacg gatgaagcag gcaaataata tgggattctt tatggctaaa attctcttgt
    12721 tcttaggttt agtaggagca gcatatctcg tgtatgcgct cctttcccaa actgatgaca
    12781 aagaagatga caacaacgat gaaatgaaat tttaggagga gaaataatgg acgaactaat
    12841 cacaaaagta gagcagtggg ctaaagacaa gggactggat caagcagatc caaaagcaca
    12901 gtttttgaaa gtagctgagg aattcgggga aatagcttcg gcgatggcaa gaagtaatga
    12961 tgaactattt aaagatagcg taggagacgt tatcgtcacg ctgattatcc tttccatgca
    13021 aaaagggaca aacgtacaag agtgtttaga aatggcatac aacgaaatca aaggacgcac
    13081 agggaaaatg gtagatggtg tattcgtgaa gtcgagtgat ttggagggca gcaaatgata
    13141 aaaaagctca ttcaattcag catggattta tatgatatcg aatcaggagc aacactatct
    13201 gtggaatcgg accatctaat cataaatttt ggtggaaagc gccagattat tttgtgggta
    13261 gttgatgatg tactgtttcc agaaattgtt catgatttcg aagaatcaaa agcggttgag
    13321 tttgaaatag tgaaaaaagt aatggaattg attgaaaaat acgaggagga cagcgaatga
    13381 taccgaagtt tagagcgtgg gataaacgaa agaacgtaat gagagatgta gccgtcttgc
    13441 attttactaa aaacggcaaa acaaacttta ttgaatattg gataaatcct accgaattga
    13501 aatcatatca cgtgcgaaac atcgacctca tgcaatccac aggaatgaaa gataagaatg
    13561 gtgtggatat atttgaaggg gatatagtat tagtcagcgt gcgaaatggc ttcgattact
    13621 tagataataa agtttgtatt gtcaaaaatt caatagatta ttccggatta gtttgtgcca
    13681 ctgttgatga agacttagag tatcaaattt ttaacacaga gctgtttgaa gaatacacgt
    13741 atgaagtcat cggaaatata tacgagaata gcgagttatt ggaggtagag tgattatctt
    13801 agctactgac tacatcgatt ctttaaaaga tgaaaatggg aatgtcccag cattgctaaa
    13861 ttgtggaatt aaaagcaaga atagaatcat tttgttacgg atatcggctg atttagcaaa
    13921 atatctttat ctgagcaaga cagcagtata ttacactgcg gctacacgtt atcagtacaa
    13981 gggaaaaaca atcagtcagg attattatga tcgtttaatc agtcctgata tgtatgggaa
    14041 ttcagaatca gcaattaagc tgtttggcgc aatagagata tatgccgatg attttccaaa
    14101 tttatggttg aaggaggaag cggaatgaaa tacgaaatac cactaagtga agcagacgtc
    14161 cagtcaatta ttaacggtcg ggaggttaat aaaaaacttc ctgatggtac tgaattagtc
    14221 atcagacaaa gttatttgaa agatatggca gctccagtat taattgatcg ttttaacgtg
    14281 actgattctg tggtagagaa ccacttgaaa gaatttcgat caagtataaa cgacactttc
    14341 agattaggga gttgattgac aatgaacacc agacaccgca gagtagcaaa actaagaaaa
    14401 caggaactga atgtactaaa gacaaagttt gaaaaagaat atggaatttc agcagaagaa
    14461 acatataaag tggcaagtca gtgtgttgct gatgcaagtg atgctattcg taagtttgga
    14521 atttcgatat taagtgatga tcgtaaatgg gaggaaaaag aatgaaacta aaagacggat
    14581 tttacgctag cagtcacggt atcggcggtt taatgctaga tatgccgaca aagaatccta
    14641 aaacacgtaa gaaaccaaaa gtcaaagtcg gtgacatggt ccgctgtgaa gcagaggagt
    14701 tcatttatcc atttcgtgga tatgtagaac acgtctataa tcactcagcg atcattcgca
    14761 ttgaaaacac gatggaatgt gataaatgga cagctaaaag caaagagaat ttagcagtag
    14821 tgagattggt ggatatggaa ctaatcaatg acaaataaaa aagccggatc gctccgacta
    14881 acataataaa acagacaagt ttattatatc acataaaagg agcagtttga attgatgcaa
    14941 ttgttacgag aggtagattt caaacagaca agatgtaatg cgagagatgt gctgaagaac
    15001 tttcggcgtt tggagcggat ggcaggtcgc tctttgatag atattaagtc gccgattatt
    15061 acggatatgc cgaaggcacc gaagcacggc aataaggcag aggatgcatt gattcagatg
    15121 atggatatag aagcggagag agacgcgatt ttagcggctt tgatggctct tagtctgatt
    15181 agtcgtcaga tactctacta cagtttttgt gtgccagaca gcttctcaaa ctacagaatt
    15241 agccgtgaag tgggttattc agaaagaagt atacaacgga tgaaatcgga agctctaata
    15301 gagtttgcag aagcatataa acacggaaga ataattgctt ataaataggg ggaccatata
    15361 atgtggaaag attatgtatc gttgaaagag ttgaaaaaag atcttgtttt caaaagaatt
    15421 gtagaatggt cagagagtga attaatttta gaagatggaa ccaaaatgga agttgtatgt
    15481 agcgaatcag attgctgcgc atgggccgaa ggtgaattca aaaatgtaaa gcttgatgca
    15541 gtgattacag atataaagat ttttgataaa ggtaaccgtc tctataatgg tgacggacat
    15601 acctcttatg ctgaagtcgt tgtttatcat aatcgtaatg agatcgctaa agcagaatgc
    15661 acagcgaatg atgggaatgg cggctactat tatagtgttt gtgctttaaa ggtcaaagac
    15721 aaactttgta tagtgactga cgcataaaaa aatggcggtt ttttggcgga atgatggcgg
    15781 tttttagcca tttatcagtg atattatggt agtgtcgaaa gattagtgat aggtctgaga
    15841 caaaataata ataaaaggaa catcgtttta ttattgtttc acaattaagc ttcgatagac
    15901 agcaacggaa atattaagaa taaggatgtg aattttaact ccttctaaat tgttcttatt
    15961 atctatcatc cgttgctgtt tattgttaca tacagatcgc ttaggcggtc tttttatttt
    16021 ggccgaaaac ctacattttc gatggccgat tattggagga ggaatagcat gttcaaacta
    16081 tctgaaatca ttaagaagtc cgacgttgag aaattagaga tgttaaaaaa gaagttgaag
    16141 aaatagcagt ctcttcgtga ggctgtttta ttttgctcac aaaaatagac cactatcggg
    16201 taatagtggt caggaattaa atgaaaaaga tgttagggtt gttagctaag tataacatca
    16261 taacgcttac aaaacaatgc aagaaggata aattattatg agaacttact ggtatgtgtc
    16321 attaaacaat aaatatccga agccaatgaa aggacagcat aggcgtgtag tcatgtctgt
    16381 tcaaatgaag gcgaagtatt cgattgtaga aatgctaaga gaagctacac caaaagagat
    16441 tgatcagtat aagttggttc ttattggcat tggttggttt aaggatgaac atattcaaac
    16501 aaacatgaag aggtggttga gatgaagtta tattatgttg aaaaagcaaa ttgttgggtg
    16561 gttgaaggct gtctgtcaaa gtacgctaca gatattatat ctactcaatt ttcagagttg
    16621 ggattgaagg ttatcttttg tggtgagttt gtcagtgtga aagaagcggt attgccaatg
    16681 acagcaaaga gcagacgctc gcgtggttca agtt
//
LOCUS       DADVXK010000058        16656 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.059, whole genome shotgun sequence.
ACCESSION   DADVXK010000058 DADVXK010000000
VERSION     DADVXK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.059"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..546
                     /locus_tag="KB909_001803"
     CDS             <1..546
                     /locus_tag="KB909_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBB6837824.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSLVQFRKTTVTVV"
     gene            735..1403
                     /locus_tag="KB909_001804"
     CDS             735..1403
                     /locus_tag="KB909_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBB6837825.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1603..1833)
                     /locus_tag="KB909_001805"
     CDS             complement(1603..1833)
                     /locus_tag="KB909_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837826.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1960..3342)
                     /locus_tag="KB909_001806"
     CDS             complement(1960..3342)
                     /locus_tag="KB909_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6837827.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(3498..4685)
                     /locus_tag="KB909_001807"
     CDS             complement(3498..4685)
                     /locus_tag="KB909_001807"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBB6837828.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4692..5723)
                     /locus_tag="KB909_001808"
     CDS             complement(4692..5723)
                     /locus_tag="KB909_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6837829.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5769..7193)
                     /locus_tag="KB909_001809"
     CDS             complement(5769..7193)
                     /locus_tag="KB909_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6837830.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            7368..8273
                     /locus_tag="KB909_001810"
     CDS             7368..8273
                     /locus_tag="KB909_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6837831.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            8364..9041
                     /locus_tag="KB909_001811"
     CDS             8364..9041
                     /locus_tag="KB909_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6837832.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            9038..9208
                     /locus_tag="KB909_001812"
     CDS             9038..9208
                     /locus_tag="KB909_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837833.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            9322..10218
                     /locus_tag="KB909_001813"
     CDS             9322..10218
                     /locus_tag="KB909_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6837834.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(10273..11643)
                     /locus_tag="KB909_001814"
     CDS             complement(10273..11643)
                     /locus_tag="KB909_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6837835.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11881..12627
                     /locus_tag="KB909_001815"
     CDS             11881..12627
                     /locus_tag="KB909_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6837836.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12624..13463
                     /locus_tag="KB909_001816"
     CDS             12624..13463
                     /locus_tag="KB909_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6837837.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            13464..14414
                     /locus_tag="KB909_001817"
     CDS             13464..14414
                     /locus_tag="KB909_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6837838.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14555..15307
                     /locus_tag="KB909_001818"
     CDS             14555..15307
                     /locus_tag="KB909_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837839.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            15326..16477
                     /gene="queG"
                     /locus_tag="KB909_001819"
     CDS             15326..16477
                     /gene="queG"
                     /locus_tag="KB909_001819"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBB6837840.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5417 a         3098 c         3338 g         4803 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa
      301 ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca
      361 cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac
      421 tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg
      481 ataaaacaga aattaaactg gcaaagtctc gtccaatttc gtaaaacaac cgtaacggtt
      541 gtgtaaaaat atcattttag agcataaaaa aaaggagtgg atttctccac tccaaaaaag
      601 tctaactttt gggggtcact acagtgtcac agtccttttt ttagtaaaag gatacatttc
      661 ttccttgtat attccatgcg tgttcgtgag aaagcatata taatttaatt aacagatagt
      721 tagggggaga aaaaatgatt ttttcaatta caatgaaact ggtgttcggg ttgatcggtt
      781 tattattagt ggtacgtttg cttgggaaga aatccatgtc agaaatcaca ccgtttgatt
      841 tagtctatac gcttgtttta ggtgggatct tagaagaatc aacctatgat gacaatgtcc
      901 atgtagggca tgtcctattt gccattgcgc tttgggcagt aatgatttat ggtatcgaac
      961 gtatcgtcca aaaaaatgaa aaggtcaatc gttgggtcaa aggcgagcca tctgttctaa
     1021 tcaaagacgg cgtcatcaac atgacagagt tgacaaataa ccatatcgag atggagcagt
     1081 tgcgagcaat cttaagacag caagaatgct tttttcttga aaatgccaaa catgttatcc
     1141 tagagaatgc cggtcaaatg agtgtattga aaaaatcaga tgaagacaaa gctttatcga
     1201 tcctgcttgt agatgaaggg caaattcagc ataaagtgct tcagtccaat caattgactg
     1261 aagcatggct tatggagaac ttgaagaaag aaggctatgc agatgtaaaa cagctgattt
     1321 atgttgaatg gtcagaagaa aaagggctct acatactaaa taaagaagac gtcatgcatg
     1381 aatcttaccg aatagatgga tagatagaca gaggttgtga aatcagcgcc ttggcttgtt
     1441 actcaaaact aagcgacttt ttcacaacct ctgatatcta atatacgttg ttccagaagt
     1501 tgcttcttcg aaaaataagc caaaattcca caaaaattta agaagcaatt ttcgaaaaat
     1561 cctttcttat tttttgaagt tgatcacttc tgtcacaacc tctcatgtca caaaccattt
     1621 ttttgtttcc tttaactcaa tataccgtac gtcttcccac aatatcggct gatggtcaat
     1681 cataaagtaa tcttcatagg cttcaccaat gaagtgccct tcgacctcat ccaagagtct
     1741 tccaaattca tcttttaaat tgagctgaat gattactgct ttacgagata aaaaggcttc
     1801 tgtcagtata ctatcgattt cttgcaatgt catttgttgt ttaggaagag gctgtttgcg
     1861 tgcttcttct tcattttttt gataccgttg actagttctt ccatcgcaaa agcagtcccc
     1921 cattttaatc caaatggccg atctcgatac tcgttatagt caatgaattt ttttgctgtc
     1981 cgtctcatct tttccacctt ctaatccact cataccacct gcatgcccgc caacgagaga
     2041 actacgtgcg atggcgcgtc ctccttgcaa gagactatgc gcatggatga ttgattgaaa
     2101 gccgtatttt tttctaatcg tatcgacaac aaaatcaact ttcgcttcat ttatctgctt
     2161 ttcaggatct tcaaaaaggt taagctgtaa acctgtcgcg tatacgaggt cggaacagtt
     2221 cacgcctaca cgccgaatat cctggtagtg gtaatgctgg tggaaaatgg tcaataaagc
     2281 atctgcaaga tctctgctag catttgtcgc ttcgattttc atttgctggt gaaacccggt
     2341 cttgccattt ggatcaagat agcctaaaga gtatcctacc cataagctga ctacttgtgt
     2401 ttttgctgca gatcgtctca agcgagtgcc gacttggtcg gccatttctt tgataacgat
     2461 ctcgatttct tctcgtcttg tataatctct atctaggatt tgactatttc cgatactttt
     2521 tgattttggt gtatattctt gtcccaaaaa acttcgatcg atgccccaag catgggcata
     2581 aagctgagta ccgatgaccc ctagcttgct tttcaagtga taataatccg cgtgagctaa
     2641 atcataaaca gaatgtatac ccatttgttt cagacgtttt gctgttcgtt tgccgattcc
     2701 ccaaaagtca gtgatatctg agattttcca taacttttct ggtacatctt cataacgcca
     2761 ttcagcaaac atttgctttc cgtcttttga gccattgtct aaggctagtt tagcaagtag
     2821 cgggttatcg ccaattccta tagtcgtgta gattccggtc tgctcaaaca catctttatg
     2881 gatcagttta gccatgtcgt acgcatttgt tttaccaaag agtgccatgc tatttgttac
     2941 atcaaggaag ctttcatcga cggaatagac atgatggttc gcttcgtctg catatttttt
     3001 atagatagaa ttgatttctc tgttcttttc catataatag gccatccttg gggcaacaat
     3061 atataaatca cttggatagg ggaagggaag atctctggca cggctgatat tggtgatgcc
     3121 gtaagctttt tttgctgcag gactggaagc caagattaat ccgctacccc gtgtttctgt
     3181 cgaatcggac ggataggaca tgactactaa tttagttgta aggggatcaa gatccttttc
     3241 aacgcactct acggaggcgt aaaaagattt gcagtcaata cataaaatat ctcttgaagg
     3301 ttctttttca taaacaaata ccggattttg attcgcccac ataacaatca cctcttcaac
     3361 acaattagaa cacacgttct ctttccgtgt caataaaaaa cagcaatttt caaatacgag
     3421 caaaaggctc acatttggaa attgctgaga ggttattttt atctatttgt ttttagctga
     3481 gatcgttgat ttttttatca aacatgaaca gcttctggat cgatctttgt tgtcccattt
     3541 ccaatgtgtg caacataaaa ttccggagca tagccgacaa ctttcatgta ttcatcatag
     3601 acattgtttt tgaaggcagg tatattttct tctttgacaa gagcaatcgc acagccacca
     3661 aatccagctc ctgtcattcg tgcacctaag acaccttctt gtttttgagc agcatctact
     3721 agtgtatcta attcgatccc agttacttca taatcatagc gaagagagtg gtgagaatca
     3781 tttaacagtt gaccaaatgc ttctaagttc ccagcttcta attcagcttt tgccttcaaa
     3841 gtccgctgat tttcagaaac ggcatggcga gctctgcgta tcaatgtatc atcgccgatt
     3901 tggtcaatag ttgattcaaa ttcttcttca tctaagtctc ctaaagaaga gataggcaaa
     3961 gttttttgca aacgtgccaa ggcttcttcg cattcgctac ggcgttcatt gtattttgaa
     4021 tctgccaatt cccgccgctt attcgtattc atgatgacga ttgcataacc atctagtttc
     4081 actggaacca tttcgtattt cagcgtattt gtatctaata agattgcatg atctagctca
     4141 ccgaagccga tggcaaactg atccatgata cctgaattga caccgatgaa ttcattttct
     4201 acttttttac ctgtttggac tagttccaag cgatctgttt ttaaatcaaa cagatcttct
     4261 aatacaacac ctactaataa ttctaatgaa gcgctactgg aaagtcctgc accattaggg
     4321 attgttcctt ccactaataa ctcaaaccca tgatcgattg agtgtccagc ttcttttaat
     4381 ttaaggacca ttccttttac gtaatttgcc cagtttgctt ttttatcata ttctagctca
     4441 tctaaagtaa aactaatgac accgatatcg tcaaagtttg tggaataaac taatatttta
     4501 ttatcgtctc gaggtgctgc tacaccttgc gttccataag tgatggaagc ggggaagaca
     4561 tggcctccat tgtaatctgt gtgttcacca atcaaattga tgcgtcctgg tgagaagtat
     4621 tgtgtagttt ttttaggtcc gaatgtttcg gcaaattttg tgtttaagct tcttttgatt
     4681 tccatgatga gttattcctt tcttgttttg attttgaatt ctgttactgt ttcaaatact
     4741 gatccggctt ttaaatgaat cgaaccaaat gctgagaagc gctctgcacc tggagctgtt
     4801 tgagtctcaa atgtgatgcc accgtgatgt gccagttttc ggttgcgcat ttctggtgtt
     4861 tctgtgccga aatttgcagt gaaaataacc acactagaag catctgtagc aatatctact
     4921 tggattcttt tatcggggct agtcaagcga gcggcttctt tacccaagcc ggtttctttt
     4981 aagaaaaatg gatgatcgat tccgtcaaca agattttttt gatccaaatc actagcaaaa
     5041 acggacgcta attttttagg tatttgaaaa tcgaaagcac ttcctgcagc attttctttt
     5101 acccctatag gaatactatc tgttcgcaaa ggagcataag cttcgctatt gagccaaagc
     5161 tcatgttgat cgattgactg agaagcatct cccgtcaagt tgaagtaaac atgatttgtc
     5221 ggattgaata aagtatcttg gtcactggtg ccgcgagagg tcactcgcca gatattatct
     5281 tttgtcaaag tatagcggat ttccacatcc attgtacctg gaaaaccatg ttctccgtcg
     5341 ggacttgtag tagtaaaaat gacagaagct tcattttcgc cattcaaaat gacataagac
     5401 cattttttta attcaaatcc aggagcacca ccatgcagat tatgtccagt ttttggatct
     5461 gtggctaatt ggtaagtttt tccattgaga gaaaagcggc cattttcgat tctccctgcg
     5521 gtgcgaccga tagaagcacc gatatacgga tctttttcga tatattcttc agcggtgtca
     5581 aatcccaaaa ctaattctcg atcatttgat tttaaactga cgattctagc acctaaatca
     5641 gagatagaaa gtgctagctt gtttttgttc tccaaggtta tcaagtgata accttggcca
     5701 aaatcttttt ctgtaatctt cattttcaag atcctttctt aatgggaagg aactactgca
     5761 tcgtgaagtt aatcttccat tgtatcagct ggagccaatt tgttttccaa tttctcaacg
     5821 atttgtgcat gttttttctc tgtcaatgta atcttccaag caaaaataat agcggagaaa
     5881 atcatcaaag cagcaggagc atagaatgca taagctttga aagtcgttac gccatgagca
     5941 gtgatatcag cagcagtagc attaccagtc atcccagaag cgatagcgac aaaccctacg
     6001 atcccgttag acaaagcacc agcgatttta tctagtaaag ggcgaattga tagagtaaca
     6061 gcttcgttac ggataccatt tttccattga ccatattcaa cagagtctgt gatcgtcatc
     6121 aaagcggata agaaaatcaa ttgttgaggg aagtagaaca atactagccc gatgataacg
     6181 attggcaaac ttgaacctgc gatcgtaaag aaaaagtaag aagaaatcat cattgcgatc
     6241 cctccaaggt aaacgtagcg acgagagatg acgcgtgtaa gcattgggaa tagtggaaca
     6301 gctactaaac caagtaaggc agcaactaga ccaacgatcc aaaattcagt tggttggcca
     6361 agtacatatt tgaagaagta gaataatacg gcagttgttg ctgcattggc aatcgcataa
     6421 gcgatataag caagggcaag ccacatcaac tgatcatttt gagcaactgc tttgaacaca
     6481 tctttgatcc cagctttttc attttgctga cggatcgcag tatcgacttc ttttgtgccc
     6541 aaggcagtga taatcgcagt accgcctgaa ataacagcag caatcacacc gaaccagaac
     6601 cagcctgaag cgccttcaat atgtttatga gtaacaagat aggtaaagaa agtaacgata
     6661 gggacaacga ctagagtagt accatttgca cctagagaag agccgaaacg agcaaacgta
     6721 gcaaattttt cacgttcctt tgtttccgta ctcaaagctg gaatcattga ccaaaaagcg
     6781 atatccttaa atgaataaaa actatccaat aagatgaaaa cgattgcaaa taatatgata
     6841 aataaagtcg tattatgagt agctaagcca aagaaattgg taaagattgc taccaagagt
     6901 acggaactaa caacgccgcc gataactaac catggtttga atttaccgta ttttgtacga
     6961 gtattatcga tgatgccacc aatcaaagga tcaaaaataa tttcaactaa gcggatacct
     7021 acaactaagc ttgtaactgt agcaatcatt tttgcattcg ttgccttatc tgttcctgcg
     7081 aacatctggc ttgtcacgaa taccataaaa taagtgctta atgtaacata gaatgtgtcg
     7141 tgtccaaaag cgcctaaagc gtaggacaca cgttggatca ttttgctttt cataatctgt
     7201 attcctctcc tgttcaatat ataatactaa gtaaaccggt tacaacgaat aacaaagatc
     7261 ttttaatgac ttaaacttaa caagaaatcg cttccttttt aatatatttc tgtgactttt
     7321 atttaacttt ttgttgcatt atactaaagg agtaaggagg gatagacgtg gagcaatcga
     7381 tttttttaaa aaaggaacat caacaagtag aaaaagaatt gtattttgat ttttgtggtt
     7441 tctctaaaac gatgccgttt cattcttttg gtcctgctat tcgcaatgat tacatcctgc
     7501 atgtcgtgat ggaaggcaaa ggatcttatc atgtgaaaaa tcaacaattc caattgaaaa
     7561 aaggtgatct gttcttgatt cgtccaggag actcgacgtt ttacttatca gatggagaag
     7621 atccgtggat gtattgctgg ctttcatttg gtgggagtgc tgcagaagaa atcattcggc
     7681 agtcgctttt cagagaagac caatacacga tggtctcttc tgacatacaa aaatatatcg
     7741 acattatttt agaatgcatg aaagatacgg aagaaacctt ggaaaatgaa ttacagttaa
     7801 cagcattaac ctaccgtttt ttatcagtcc ttttaaaaga tggcggaaag gtcagcggtg
     7861 gtgtacaaaa ggttcattcc tctttagctg ttgaaacagt caaatacatc gaggcacatt
     7921 atgctgaaaa attgtctgtt gaggaaatcg cccagcattt agcggtcaat cggagccatt
     7981 tgtcgcgagt attcaaaaat catatgggta ccagtatcaa ggaatatttg atcggggtac
     8041 ggatcaatcg aggggcgttt cttctttctc tgacggatga atccgtggaa agtattgcct
     8101 atcaagtagg gttcaatagt ctagtcgtat ttagccgaat gttcaaaaag agtaccggag
     8161 aaacggctac gaactatcgt aaacgtatga aaaacgaaaa ttttaagaat attgctttgg
     8221 ataccttgaa aaaacagttg gaaaaacaaa ccgcagtttc ttggacaacc tgattagtct
     8281 ggttaaaatg acaagcatcg gcaaaagaaa cttgtggcgg ttatgctaca ctgtaaagcg
     8341 aagactaaaa aggaggaaaa gggatgcgta cacttatcat cattagccat ccaacgatcg
     8401 aagaatcttt aaatcagcaa tttttcaaag aagcttctgc tggtttacca gctacttggc
     8461 atcatttgga atcaagttat ccagacggaa aaatagatat agagactgaa ctacagctct
     8521 tggcccagca tgatcggatc attttccagt ttccgtttta ctggtatagt tctcctgctc
     8581 atttaaaaat ttggcaagat aatgtcttgg aacgagcagc acatgtatta aaagggaaag
     8641 aactaggaat cgtattgaca acaggtgtgg cggaaaaaga ataccaagct ggaggaaaag
     8701 aagaatatac gatttccgaa tttttgaggc cgtatcagcg aatcgcaaat aaattccata
     8761 tgacctatct tccgccattc gttttagcac aatttatgta tttatcccag gaaaaacgtt
     8821 gggagaagct aattgcttat cagcagtatc tctcattgga aggcaaacca tcgctgactc
     8881 agcggattga ctggtttatt caaagagtac aggaaaatca gaaaatgcag gaagaagaat
     8941 ctgaaaaaca agcatatatc gtagaagcac tgactgaggc aaaagagcag atcgaagact
     9001 tgacctttac actgcaagaa atgaaaggaa cttcattatg acaaatgatt ggctgatcca
     9061 acaattagat gaattaagcg aaaaatcaga atatcaagac cgtgcgctct tatatgaaat
     9121 aaagaaactg atggctgaga tagacgaacg aacaatgcag ctgcaaggag aaatcgacgg
     9181 acaatcttgg aatcatctca actggtgaaa ttttcttata aataacaaag ataaaaatgt
     9241 gcacagcgac aattatttgc tacaataaga atatgaagcg tttgataacg ctattataca
     9301 taaaaattgg tggtgaaaaa aatgtatgat gaaaatgagt ggggagaaaa tgttcggatg
     9361 acccgaagaa gacagcaaaa acaggcagct cgtaagcgga tgatcatgat tggggcagca
     9421 gttgccgtgt ttttgatcat agcaggagga gttgcgggtc tatattttca tggaaaaaat
     9481 tcgtcagaag cgaaaagtac gaccataacg gaaacaacga caaagaaaac agagacgaaa
     9541 caaacaagtg agtcatcaac taaaacaaaa gagacacaaa cttctgaaga aaaaacagca
     9601 aatggtttgc cagagcaact tcaagcaatc gtaaatgatt attcgaaaaa gatcgaagaa
     9661 aagacgcctg cattgattga agaataccag acagaaattc agggaaatca agagggaata
     9721 gctggtttat cagcagttgc taaccaaaaa gcacgtgagc ttcaagcaat ctccgacgaa
     9781 gggatcagaa aattacgtgc agcgtatcag gcagcagaaa ataaagacgg tgtagactta
     9841 gatactttga tcaatcaatt atcggctaat tatacgaatc atgtcgctaa gatttccgat
     9901 atttatttgc agactagcgc ctctcttcaa gcagagtcaa caagcacaca agacacaaca
     9961 tcttctgatt ctgagacagc agagtcggta gaagcttctg aaatgcaagc tcgaacaaca
    10021 caagacacaa cagattcctc tgaaactaat accaacagcg cgacttcaca ggctgcgaca
    10081 accgtagttt tggaaggaga aggtccaaat caaatagccg aacgaactgg cgtaccagta
    10141 gaaacgatct tgtcgctgaa tgggatgagc atggagaatt atttcctgac tcccggtgag
    10201 acgctaaaat tgaattgata aaagcaataa aaaagaacga agcttccact aaggtgaagc
    10261 ttcgttcttt ttttattttc cggttctttt ttcgcgtaca aagtaatgga tcgtcatgta
    10321 aagcaagaaa acgagtccaa taatcaatga gattctcgtt tcaggattga taaacatgaa
    10381 aatcaatacg atagctaaaa aagcaagtgt cacataattc gtataaggag atagtggcat
    10441 tttaaaagga tgatcatgca ttttatctgc gtgcttcttt ttgaagcgaa tctcgctgat
    10501 caaaatcact acccaaggaa ccataccagg caaaatactt gagctgtata cgaaaacgaa
    10561 aatattttct gactggttga tgaacattgg tagaagataa tttaagatca gaccaattaa
    10621 gattccacct gagattgcta cgacaggata aaaaggcgca ccgtgacgag atagtttcag
    10681 aaatttttta gacatctttc catttatggc aagtgtatag accatacgac ttgcgctgaa
    10741 aatccctgaa ttgcaacctg ataatgccgc tgtaatcacg acaaaattaa tcagtcctgc
    10801 agcaaatgta atgccgactt tagaaaaagt ttgtacaaaa ggtgaaccaa tctcactcaa
    10861 ttgattccac ggatagatac tcacaatgat aaaaatagca ccaatataaa aaatcaagat
    10921 tcgaccgata gtggactgga cagcttcaat gatcgtcttt ttaggattct ctgcttcacc
    10981 agcagtcatt ccgatcagtt cgattccttg ataggaagca acaacgatcg ataatgcaaa
    11041 gaaaaatcct ttgacgcctc cagtgaagaa tccaccattt ttccaaagat ttgaaatccc
    11101 tactgcctga ccatgattac caaatccaaa taagattacc ccaagacctg caatgatcat
    11161 caaaatgatc gttatgactt tgatgatcga aaaccaaaat tctaattcgc caaacgcctt
    11221 gacagaaata agatttgcca gcataagaaa caagacgaca atgattccgg gaataattgc
    11281 cggcaaatca ggccaccaat aattcatata agatcctaca gcaatcactt cacttattcc
    11341 tacgacaata tattgaaaaa tattactcca agcggtcaag tagccagcca caggatggat
    11401 gtactcgctc gcgtaatttg caaaagaacc agtcgaagga tcaacgtaaa gcatttcgcc
    11461 taaagcacgc ataatcaaat acaaaaagaa tcctgcaatc gcataggctc ccatcactga
    11521 gggccctgtc caacgtatgg ttgaggaggc acccataaac agaccgacac cgatcgttcc
    11581 acctagtgcg atcatttgga tatgacgggc actaagactt cgagttaact tttcttcttc
    11641 catacaaaaa ctcctttcgt tgttgagtca acaagaaaaa ataatcaaac gtttcaacac
    11701 atgtttttca ttattaggtt agccttattg aactcttgat gtgattctac agaaaatttt
    11761 cataaaatgc gaggaaaatt cgaaaaaaac tttttcatca ttctacttga aaatgctttc
    11821 cattttagtt aaactatatt taaataaaaa gttaggtaaa cctaaaaagg agtgtaagat
    11881 ttggaacgta cggccattgt aattcaagac ctttcagccg cttatcaagg gaaaactgtt
    11941 ttgaaaacta tcaacttgac gataaatcca caaaaaatta ccggtattat cggaccaaac
    12001 ggtgcaggaa aatcaacatt tatgaaatct ttgctagagt tgataccagc tactactggt
    12061 aaagtcacct tttctggaca gtcggtaaac tcagtccgta aaaaaatagc ctacgtggaa
    12121 cagcgaagtg aattggatct ttcctttcca attgatgtat taggcgttgt acttttagga
    12181 acatatccat ctttacgaat tggacaaaga cctgggaaaa aagaaaaaga acgtgcaaga
    12241 caagctttga aaaaagtagg gatggaagaa tatgccaaaa gacagatcag cgaactatcg
    12301 ggtggacagc ttcagagagt ttttattgca agagctctag cccaaggagc agaatggatc
    12361 tttttagatg aaccattcgt agggattgat gcgttaagtg aacgaaagat ctttgacatc
    12421 ttgcaggaat tgaagaattc aggaaaaacg attttgatcg tccatcatga tcttcataaa
    12481 gtagaagaat atttcgatga ggttattctt ttaaataaac agctgatcgc ttccggtcca
    12541 gtacaagaag tctttacatc gaagaacctt caattggcct atggtgagat catcagacat
    12601 ttagtaaaag gaggagagaa aaaatgatcc aatcctttat tgatggatta atgaattatc
    12661 aattcctgca atacgctttg gtcacttcca tgcttgtagg acttgcttct ggagtcatcg
    12721 gttcttttat tattttacga gggatgtctt tgatgggaga cgctatctct cacgcagttc
    12781 ttccaggtgt agccatttct tatatgtttg gttttagtta catctttgga gccactgctt
    12841 ttgggatgct aacagcagca gtgattggtt tcgtgactca gcggagccga ttgaaaaatg
    12901 atacagcgat tggaattgtc tttagctcct tttttgcatt agggattatc ttgatttcat
    12961 atgcccagag tgcgacagat ttgtatcata ttttatttgg gaatgtctta gctgttaggg
    13021 aaagcgattt gttgctgaca gcactcgtta gtggaatcgt cttgatattt gtctttttct
    13081 tttataaaga attgaagatc acatcattcg atccgacaat ggcaaaagct tatgggctga
    13141 acacatcgct gatccattat cttttgatgt tctttttgac attagtggct gtagtcagtt
    13201 tacagacagt aggaacaatc ttggtgattg ccatgttgat cacaccagcc gccacggctt
    13261 acttgctaac gaaccattta ctgaaaatga tcattacagc tgcaggaatc ggtatgctaa
    13321 gtgcagttgt cggtgtgttt ttcagttata gttacaattg gccatcagga gctacgatcg
    13381 tgttagcatg taccgcattt tttatccttg cttttttatt ttctccaaca aaaggaattt
    13441 tatttcagaa aggaagcaga tagatgaaaa caaaaaaatc actcttttta atcttggcag
    13501 ttagtttctt ggtattagcc ggttgcggaa agcaggcttc tgaccaagcg gatgaaggaa
    13561 gtaaagaaaa gttgtcagtc gtggctacca attcgatctt ggcggacatg gcaaaagagg
    13621 tcggaacaga tcaaatagat atccacagta tcgtaccagt cggaacagat ccgcatgaat
    13681 atgaagtact accagaagac atcaaaaagg caagcgatgc agatgttatt ttatacaacg
    13741 gtttgaatct tgaaacaggt aacagctggt tcgataactt gatggaaacg gctaaaaaag
    13801 aagaaggaaa agattatttt gcagttagca aaaatgtaga acctctttat ttaactagcg
    13861 gtgaagaaca tacaaaagca gatccccatg cttggctaga cctatctaac ggaataaaat
    13921 atgtggagga aatcgcacgt atattctctg aaaaagatgc agaaaatgcg acactctata
    13981 aaaaaaatgc agaagcatat gtggaaaaac taaaagaatt agatacacaa gcgaaggaaa
    14041 gttttgcttc tatcgaagag aacaaaaaat tattagtaac aagtgaaggg gcattcaagt
    14101 atttttcacg agcatatgat ttgccagcag cttatatatg ggagatcaat acagaaagtc
    14161 aaggtacgcc tgatcaaatg aaagcgatca ttgatcagat aagagcaaaa gaagtaccgg
    14221 ttttattcgt ggaaaccagt gtagactcaa gaagcatgga acgggtagca aaagaaacgg
    14281 gtttgaaaat ctatgataaa ctgttcactg attccatagc aaaagaagga gaacaaggag
    14341 attcttacta tcagatgatg aaatggaata ttgaaacgat ccatgaaggt ttgtcacaaa
    14401 caaaagaaag ctgaaaagtg caaggtctag cttgaggagc agaccttgca ttttttataa
    14461 gagatatgaa aaaaaattat gctgtttttc gtcgtacaga tacctttttt gaagaaattc
    14521 cgttatagtt agagtaagga aggaaggtgt ggctatgaat tttacacgta aagataaata
    14581 tacgattaaa gaagaagtct ttcgattgat cagccagcag gaaaataccg acaaggatca
    14641 agaccttcaa tttcttgaag cagaattagc taaattattc atagcaaatc aaaatgagac
    14701 aacagaacca gatgaagagc tgtacatagg caaatggttg tttgatgaat ttcagccttt
    14761 agatgaaaat accggtatcg gttattttgt gttcctttct ccagtcggct tcacacctgg
    14821 cgtattagtt aaacaaaacg acgaaataac cgtcaaagca tggcctgcat tattttcagt
    14881 catcaaagca gaaggagtaa tcaaaaagat ccagtcggcc tattataaaa gtcaatttat
    14941 tgccaacagc aaattaatga atatgtttta taatcgtcta gtagaaattg ctaggcctgg
    15001 gaaaatcccg caaacattca cgtacacaca gcaaaaaaat ctctatgaag aagtattgta
    15061 ttcccgcgat ctgtctgagt tttcgccatg ggaagaggta aggctccatg aactgttaag
    15121 tacaaaacca gtttcattga atttttttaa tgcattagat aacaaaagaa aattaatttc
    15181 aacaaattat tgggaagtat ttgctgcaag aaaaaaatgg atggaagaaa agaagattgc
    15241 cgatcagcag atccagtttg tccagctgaa aaaagaaaaa ctatattatg ggttatacag
    15301 ccgttaacag caagcgagga agaccatgac attaaaagaa gaaatcatac aagaaagcaa
    15361 acgattagga attgacaaaa tcgggttcac cacggcggaa ccttttgatt cattaaaaga
    15421 atcgttggaa gaacaaaaag cagctggcca tacttctggc tttgaacatc caaatatcga
    15481 tgagcgtctt tatccagaaa tgacatttga tcagccgaaa tcgatcattt ccattgcact
    15541 tgcgtatcct actaggatcc atgaagaagt gcctagggat gaaaaacgcg ggcagtttgc
    15601 tcgtgcttct tgggggatcg attaccatga tatactcaga gaccgtttga accgattgat
    15661 cgaattcatc caaacaagag cagaaaaatg gcaaaaagaa gaggaatggc gtctagctcc
    15721 gcaagtagat actggagaac tgatcgatgt cgctgtagca cagcgagctg gtttaggatt
    15781 tattggacga aacggattgt tgatcactga agagttcggt tcatttgtct atcttggtga
    15841 gatcgttact aatattgtat ttgagcctga taaaccagga gaatttggtt gcggtgactg
    15901 tatgcgctgc gtgactgctt gtccgacaaa agcattgctt ggtgacggaa gaatgaatgc
    15961 ccagcgatgt ttgtcttatc aaactcagac aaaagggatg atgccggaag aatatcgtaa
    16021 aaaaatgcga aatgtcattt atggatgtga tatctgccag ttagtctgcc cttacaatca
    16081 aggaaaagat tttcattttc atgaagagat ggaaccaaaa gtagacgaaa tatatccaaa
    16141 attaaagcca atgctttcga tgtctaataa agacttcaaa cagcaatttg ggcatttagc
    16201 tggttcatgg cgtgggaaga aacctttgca gagaaacgca ttgattgctt tagctaatct
    16261 aggtgatcga acggcattgc ctgagatttc agaatgttta acagatgtcc gccctgtcat
    16321 cagaggaaca gcagcttggg ctattggacg tctaggaaca aaagaaccgg aaaaatggct
    16381 tgatgtatta gatgaaatat tagctaaaga aacagaagaa gtcgttataa acgaattgga
    16441 acatgcccag aaattattgc ggagaaagtt aaaataaaaa aatagttaac attattcaaa
    16501 gtttttgtcc agtaattgtt gtaacaatta ctggtttttt tgtatttttt acattttttt
    16561 aagagaattt gataaaaatc aaaaattttt ttgctttttt ttatggatta ttgcagtgaa
    16621 tgttacagaa tctgcgtttt tcattcaaaa ataaaa
//
LOCUS       DADVXK010000059        16510 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.060, whole genome shotgun sequence.
ACCESSION   DADVXK010000059 DADVXK010000000
VERSION     DADVXK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.060"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..170)
                     /locus_tag="KB909_001820"
     CDS             complement(<1..170)
                     /locus_tag="KB909_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBB6837841.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGF"
     gene            complement(564..2291)
                     /locus_tag="KB909_001821"
     CDS             complement(564..2291)
                     /locus_tag="KB909_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBB6837842.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2284..3477)
                     /locus_tag="KB909_001822"
     CDS             complement(2284..3477)
                     /locus_tag="KB909_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6837843.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3664..4308)
                     /locus_tag="KB909_001823"
     CDS             complement(3664..4308)
                     /locus_tag="KB909_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6837844.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4402..4536)
                     /locus_tag="KB909_001824"
     CDS             complement(4402..4536)
                     /locus_tag="KB909_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBB6837845.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4538..6670)
                     /gene="feoB"
                     /locus_tag="KB909_001825"
     CDS             complement(4538..6670)
                     /gene="feoB"
                     /locus_tag="KB909_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBB6837846.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6667..7140)
                     /locus_tag="KB909_001826"
     CDS             complement(6667..7140)
                     /locus_tag="KB909_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBB6837847.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7541..7765
                     /gene="nrdH"
                     /locus_tag="KB909_001827"
     CDS             7541..7765
                     /gene="nrdH"
                     /locus_tag="KB909_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBB6837848.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7924..10083
                     /gene="nrdE"
                     /locus_tag="KB909_001828"
     CDS             7924..10083
                     /gene="nrdE"
                     /locus_tag="KB909_001828"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBB6837849.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10133..11098
                     /gene="nrdF"
                     /locus_tag="KB909_001829"
     CDS             10133..11098
                     /gene="nrdF"
                     /locus_tag="KB909_001829"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBB6837850.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11187..12326)
                     /locus_tag="KB909_001830"
     CDS             complement(11187..12326)
                     /locus_tag="KB909_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6837851.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12635..13348)
                     /locus_tag="KB909_001831"
     CDS             complement(12635..13348)
                     /locus_tag="KB909_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBB6837852.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13602..14303)
                     /gene="nagB"
                     /locus_tag="KB909_001832"
     CDS             complement(13602..14303)
                     /gene="nagB"
                     /locus_tag="KB909_001832"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBB6837853.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14537..16069
                     /locus_tag="KB909_001833"
     CDS             14537..16069
                     /locus_tag="KB909_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6837854.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16260..16439)
                     /locus_tag="KB909_001834"
                     /pseudo
     CDS             complement(16260..16439)
                     /locus_tag="KB909_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         5122 a         3411 c         2869 g         5108 t
ORIGIN      
        1 aaaaaaccac ctatagacat tcctgcaata caagtagttg ccttggccca atcgaccgta
       61 catttatttt tagtgcaata cactccattt ccataatatt ttccactatg agtggtaccc
      121 ccatagataa gttgtgtctc tttaatagac aaaattttta aatgtttcat aatctaatca
      181 cccctaaatt aatgttttta gactattatt ctaacattca ttaaatttca aaaaacaatt
      241 ccttcttgaa acgtagcaaa ataattcctg aataagaatt taatcacttt taagtatata
      301 aactatgtat attctttaat attttttgag aatgcacttc gtacataata aactttaatc
      361 acattagtct ttcataccta cgatcgatct ctttgactcg cacccataaa ttcataatag
      421 tttgtcggcg tctttgaacg tttcgaagat gagctacgca ttctcttttt ttatagacaa
      481 aaaagataga gacgaacatg gagcttccaa atttggatat ttgatccaat tttggaagct
      541 ccatttattt cgtgtctgtc tttttatttt ttccagcttt cgactaattc ttggttctct
      601 ttgatccagt cttttgctgc ttgctgtgga tcttttccat tgttgatttc caacataact
      661 ttttccatat ctttttctga ccaatggaaa ttgtctaata ctttgtaagc ttctggctgg
      721 tcttctttca atccttttcg aaccatcgta tggatctgct cttcgcttcc cattccgttt
      781 tcaggatctt ctaagtattt cagatcatat ttggcaaaca tccaatgagg tgtccatcct
      841 gtaactacaa ttggttcgtg ttttttgatc gcttgaccta gtgcaacggt cattgctcct
      901 gaagaagatg tctctacttt ccagtctttc aagttgtcat atttttggat cgtgttttca
      961 gcagccgtaa ctacaccagc tcctggctcg attcctatga ttttcttacc tgcctgatcg
     1021 gttaactcat cgatcgaatt tacatccatg taggctggca ctgctaaacc aacttttgct
     1081 cctgtcaaat tggcacctag gtcttcgact tgatctttat attgtgcata ttgtgaacca
     1141 tgagttttag gtagccaagc tgaaaccatg gcatctgact cgccatttga aacagatttc
     1201 cacatgattg aattatctaa tggcgtcatc gttacatcat agcccatttg tttcaatact
     1261 tcaccgacta catttgttga agcaacttct gtatcccatt caacataaga taagttgata
     1321 cgttttgttt ctttggcaga tgaaaaactc cctataccaa tcgcacctaa gatcactact
     1381 actacagcac caatgatcag tccttgacgt tttttacttt tctgtgttgt tgctcctgca
     1441 gcttttttat tgtttggctg gttcaaatgc tgtgtaaaac ggtcaatgat gattgctaag
     1501 ataactaatg caaccccgtt gacaaatcca ttcccgactt gtgctctttg caatgctgat
     1561 aatacgccgc gtcctaagcc gggtgcaccg atcatagagg caataacgac cattgaaagt
     1621 gacagcattg ttgtttgatt gatccctgcc atgatcgtac ttttagctaa aggcaattct
     1681 agtttgaata gtttttgacg acttgtgctc ccgaatgaat cagaagcttc tactaattct
     1741 ttaggaactt gtcgaatccc taaattcgta aaacgaacgg ttggtggcag agcaaagatg
     1801 actgaggcaa atacccctgg aaccatcccg ataccgaaaa atgcaactgc tggaatcaaa
     1861 taaacgaatc ctggcattgt ctgcataaag tcaaggatcg gtttgataat actttgggct
     1921 ttactgcttt ttgccatcaa gatccctaat ggtaccccaa tgatgatcga gatcacacta
     1981 gataaaagaa caagtgtgac agtattcatc aaatcattcc atagaccttg gttataaata
     2041 aaccatagac cgattaatgt gaacaacgta agtcctggac gtttcttaga aataaagaaa
     2101 gctgctaccg tcaataacaa gataaacaaa ggagctggaa tcactaacag taaatttgta
     2161 atccccgaca tcactgcctg tccaatcgtt tgtaaaaatg aaaataggcc agaaaaagtt
     2221 gtcgtaaacc attctgtgat attttctacc cagtttgcca ctggtaattg atagttcaat
     2281 agattattca tgttcactca cctcgcttgt ttctgctaat gcttcaatca cactacctcg
     2341 gatgacgaca ccttttaatt ttccatcctc tacaactgca agtggagtcg gtgagtcata
     2401 aataatattg aaaatatcac ttaccaccat gtctttccca atcaccgtca cattttcatc
     2461 taggaagtcg atcaatggac gtttttgctt cctagcttct aacgcttgat ctgcagtgat
     2521 gatccctttc aggtgtctct ttctgtcaac agccatcagc atgctgactt cttcattacg
     2581 catccttgtc aatgcaacgt ttggtccatc agattcgata ttcgtcgtca atgcaggtac
     2641 catgatgttt tgagccgtaa gcactttgga acgatcgact tcttccacaa attcacgtac
     2701 ataatcattt gctggattgg tcaatatttc ttcacctgtt ccgatctgca tgatttcgcc
     2761 gtctttcatc aaggcgattc tgtccccaat ccgtaaagct tcattcaaat catgggtaat
     2821 gaaaataatc gttttttgaa cattggcttg caggtccagt aattcgtctt gcatttctcg
     2881 ccggatcagc ggatcaagag ccgagaacgc ttcgtccatc agcaagatct caggatcatt
     2941 tgctaaagct ctggctaggc caacccgttg ttgcatccca ccagataact gactaggata
     3001 ttggtcttta aatgaaagca aactagaatt ttctaatgct ttttctgctt tttcttgtcg
     3061 ttcttcttta ggtacaccac ggacttctaa cccgtattct gtattttcca agatcgttcg
     3121 atgtggaaac agaccgaagt tttggaaaac catattgatt ttatgacgac ggacttctcg
     3181 caattcttct ttgcttaact tcgatacatc ttctccatca atatagatac tgcccgaagt
     3241 tggctcaatc agacgattca atagacggat caatgtggat ttcccactcc cggaaagccc
     3301 catgatcacg aagatttctc cttcttttac gtcaaaattc acgtcataca caccaaccgt
     3361 tgcaccggtt ttctttaaaa tctccgtttt cggctggtga tcattcatca tatctaaagc
     3421 ggcttgtgtc tttttaccaa atatctttgt taaatgtttt acttctactt ttaccaaaca
     3481 aattctcctt ttttatgtaa attcattttt ctttctgaaa aaagtgacca cactatgtta
     3541 acatcatgta gtcactttgt caaaaatgaa agaaatttgc ttgtccaaac tgaaaaaaac
     3601 ttggctaaat ctttgtaaat aaaaggttta gccaagttaa tattttttta atatttcaca
     3661 caatcattct gcaagctgat gctccgggta aaaaaagttt gtcatacgct gtagtgtata
     3721 ttcatttcca ataaaatgaa cgatgtcccc tgccgtaaat ttagcatagg ggccaggtga
     3781 aacaagcagt tcttcattat gagaaattgc gataactgtg gcgccagtcg cctgccagat
     3841 attcaactcg ctaattgaac ggtccagatg cattgctttt tctgataaag ataattcaaa
     3901 cggaagtaaa ggattcatct tatgtattcg cttcgtttga ttgaccagct gatccaataa
     3961 ttgagaaaaa tgattcagct catcttgttg cttctccaca cttgccatga tttctgcttt
     4021 tgtatcttgg atggattgta catcttgata ttgcaatagg aaatcttttg ctttttcctt
     4081 cgaagcaaca aatgccccac ttccatgccg tacttccatg attccaagat ctaccagcac
     4141 attgatagcc ttgcgggtag tctcaggaga agcattgtac gtactggcaa gtgttgagcg
     4201 ggcatggatc ttctcaccca ctttatatcg gttttcaacg atacgttcgg ctaaatcaac
     4261 agcaatctgc tggtagcgcg ggcggacgat ttttttcttt ccagacattt tctttcctct
     4321 ttcttttttt actttccctc atcttactat gctctagcaa aataagcaaa aaaggggaga
     4381 atagcctctt gcaacgactg atcatcgctt gatctgttcc ttttttactg ggcaagctgt
     4441 ttgacagtca tcacaattct taccggattt taaacgagta tagacaattg cgcctgcact
     4501 tccaaagatt aacacactta ataagaatgt cgccatccta ttcctctcct tctaatgaca
     4561 atatagtata aaactggttc ttggattttg gctgacggaa caaaacataa acgagtccta
     4621 tcatcagtaa aatagcaaga tacgtcccta acgctacctg tccaccctcc aataagtgtc
     4681 ccaactgata aatcacaaaa ctaactaaat aagctaaacc gcattgatag cctatggcga
     4741 tccaagtcca tttcttggca ttcatttccc gatggatagc cccaattgcc gcaaaacaag
     4801 gcgcacaaag taaattgaag gctaacaatg aataagctgc tgcgggagta tatgtgtgtt
     4861 gtagcacttg ccagatttct ctgccatttt cggatacttc cgcatgacca aacaaaatac
     4921 caaatgtgcc aataatattt tctttagcga ccaatcctgt aatcgctgcg actgttcctt
     4981 gccagtttcc ccaaccaagc ggctgaaaaa caactgccag gattcgcccg aaaaaggcta
     5041 agatactttg gtcttcagaa acaggttgag cataaaaatt ataagaagag ctgaaccaga
     5101 tcacgatact agaaacaaag ataatcgttc ctgctttttt aacaaaagac ttgctgcggt
     5161 cataggtttg tcttaggacc gctgaccatt gaggaaaatg atatgcgggc aattccatga
     5221 taaaaggagc tgtatctcca gcaaacaaac gtgttttttt caagctgatt ccagagaaaa
     5281 taattgcagt cataccaaga aaataggcag aaggagctac ccaagattga tgaggaaaaa
     5341 aggcccctgc tactaaggca ataatcggca actttgcaga acaaggcatg aaggttgtga
     5401 ccatgatcgt caaacgacga tcttgctcgt tttcaatcgt gcgactggcc atgacgcctg
     5461 gcactccaca tcctgtagca atcagcatag gaatgaagga ttttcctgaa agaccgaatt
     5521 tcctgaaaag tcgatccatg acaaaagcga tcctcgccat atatccgcag tcttccagaa
     5581 agctcaagca taaaaacaat ataatcaatt gcggtagaaa tcctaacact gctcccacgc
     5641 ctgcgatgat gccgttcaag atcagctcct gcatccatcc cgctacttgc cattcagcta
     5701 acaatctgcc aacatgttct ggtaaccatg taccaaacaa tgtgtcattg atccaatctg
     5761 tccccattgt tcctactgtt tgaatagcca gataatagat cagccacatc acaaatgcga
     5821 agatcggcaa ggctaaccaa cgattcgttg caatctgatc gattttgtca ctcatcgata
     5881 attggaaaga atcatttgac acaacacaga gtgtacatag ttgggtaata aattcataac
     5941 gttcattgac cagaatcgtc tcactatcgt cgtccaatag tttctctgtt aactggatca
     6001 gttgctcgat ctctttttgc tgagaaactg ctatctcgta atcctctctt accttctgat
     6061 ctcgttcaaa atatttcatt gcataccagc gtttcttgcc gctttgttct cctagtacat
     6121 cttcaatttc atgtaaagct gcttctaaac gtggatcata tgtacaggga acaggaatag
     6181 aaggccgctt ttttgcagac tcctgaatct tttcgattag tttttcgatt ccttgctttt
     6241 tcaatacgct gattggtaaa actggtacac caagaccata ggaaagcttt tctagattga
     6301 ttttttttcc ttcttttttg atgacatcca tcatattcag accaatgatc ataggaatgt
     6361 ctaaatccaa taactgcgta gttaaataaa gatttcgttc taaattggta gcatcaataa
     6421 tgttgatgat cagttcaggc tgttcctgaa ccaaataatc tcttgcaatc acttcttctg
     6481 gtgtataagg agacaaagaa tagatgccgg gtaggtcctg aatatgaatg ttcggatttt
     6541 ttttcaacga tccttctttt ttttctactg ttacgcccgg ccaattccct acatattgat
     6601 tcgaaccagt caagagattg aacaagctag ttttcccgct gtttggattt ccgactaacg
     6661 cgatattcat tctttttcct ccctttgtat caagattagt tcggcctctg actttcgtaa
     6721 cgtcagttca taccctcgca ctgtcagttc gattggatct cccagagggg ctagttttcg
     6781 gataactatt tttacatttc gcgtcaatcc catatccatt aaccgtcgct tcactgcgcc
     6841 ttgtccgtgg attgctacga cgatcccagt ctctcctgct tttaattgat caagagaagt
     6901 ccagctttca gaggaagcag tctttttatt gacaaagatt tgacctagta tttcccgact
     6961 tactgccact cgatgacttt ttaccagtaa aatggcattg ttgcctgata aattgacgac
     7021 gacgatttta cttccggcaa cgatcccgat attttgcaaa tggcgttttg ttttttcttc
     7081 tgtttcgatt cgttcgactt gataaacgaa attctgcttt gcctgcgcta aggtctgcat
     7141 attgattcct ctcttgtgaa ataaatcatg tattaaaatc attcattata tgttctaatt
     7201 ttcttacgtg ttacgcaaat aaatgagaat cattctcaca tagaatactc tcggtaattg
     7261 agaatgtcaa ttatacttgt gatattatga gcgaatcttt agtattgata gataaaaatg
     7321 agaaaaaaat atttcttcat agttttccac aattttttct ctattaaatt tgctattttc
     7381 ccacacgata cttgttttca gctctttttt caaaaacaca aaacttagta ttccacagtt
     7441 tccacaacac aatatgtagt gtttgttgtt tgactttttt actaagagtt ttatactatc
     7501 tattatagat aataagaatg tgttagagga ggcactcacc atgaacgtaa aaatcttttc
     7561 taaaaataat tgtatgcaat gtaagatggt caaacggttt ttaacagaaa atcaaattgc
     7621 ttttgaagaa gtcaatatcg atgaacagcc tgaagcagta gactggttga aagcacaagg
     7681 attccaaagt gttcctgtca ttacttctga tgcagaaaca gttatcggat tccgtcctga
     7741 tcagttgcgt aaacttgcca gctaacatga ctaaaagaat caaaacgtga tacatggatt
     7801 tgaagggctt gagacagcac cagtttttgt cgcaaacttc caaatccttt tttaaagctt
     7861 aaaaacaatg caatgatttg caatcaagca tcatcaaata cgaaatgaag gttgggcgta
     7921 cgtatgagtc ttaaaaattt acaagatgtc agttatttca agctgaataa tgaaatcaat
     7981 cggccagtca atggtcaaat ccctttgaat aaggataaag aagctttagt tgcctttttt
     8041 gaggaaaatg tcaaaccaaa tacgatgact tttccatcta ttatggaaaa aatcaattac
     8101 ttgatcgatc aagaatatat agaagcagaa ttcattcaat tgtattcacc atcatttatt
     8161 gaaaagctat atcaattttt ggacgagcaa catttttctt tcaaatcttt tatggctgct
     8221 tacaaatttt attctcaata tgcgttgaaa accaacgacg gttccgctta tctggaaact
     8281 tatgaagatc gagtagcctt caatgcgctt tactttgcga acggggatga agaattagca
     8341 cttgctcttg cagacgaaat gatccatcaa cgatatcagc cagctacacc ttctttcttg
     8401 aatgctggac gtaaacgtcg gggcgaattg gtgtcttgtt tcttgactca agtcactgac
     8461 gatatgaact ctatcgggcg ctcaatcaac tctgctttgc aattgtcccg tattggtggc
     8521 ggcgtaggga ttactttatc aaatcttcgt gaagccggcg ctcctatcaa aggatatgag
     8581 ggtgctgcaa gtggtgtcgt tccagtcatg aaattattcg aagatagttt cagctattct
     8641 aatcaattag gtcagcgtca aggagctggc gtggtttatt tgaacgtttt ccatccagac
     8701 attattgctt tcctttcagc aaaaaaagaa aatgcagatg aaaagattcg cgtaaaaact
     8761 ctttctcttg gcgtgatcgt acctgataaa ttttatgaat tgacacgtaa aaacgaagat
     8821 atgtatttat ttagtccata tagtgtcgaa aaagaatatg gtgtcccatt ctcttatgta
     8881 aatattacag ctgagtatga tcatctagtt gcaaatccaa acattcgcaa acaaaaaatc
     8941 aaagcgcgtg atcttgaaaa tgaaatctca aaattacaac aagaatctgg ctatccttac
     9001 gtaatcaata ttgatacagc gaaccgcgag aatccaatcg atggcaagat catcatgagt
     9061 aatttatgtt cagagatttt acaagttcaa acgccttctg tgattaacgg caaacaggaa
     9121 tatgaagtat taggaacaga tatctcatgt aacttaggct cgacaaatat cgtgaatttg
     9181 atgcaaagcc ctaactttgg tcaatctgtg cgtacgatga ctcgtgcatt gacatttatt
     9241 acagatgcat ctgatatcga tgtcgtacca ccgatccaaa acggaaataa gctgaatcat
     9301 acgattggat taggtgccat gggcttacac acttatcttg caaaagaaca aatggaatat
     9361 ggctcagagg attcattaga ctttacaaat atttacttca tgctgttgaa ttattggaca
     9421 cttgttgaaa gcaacaatat cgctcgtgaa agaaaacaag ttttccataa ttttgaaaaa
     9481 tcagcttatg ctgacggcac ttatttcgaa aaatacgtaa ctggagaatt ccagccaaaa
     9541 tcagaaaaag tcaaagcatt gtttgaaggc atttttatcc caactgctga agattggaat
     9601 gctttgaaac aagcagtaat gaaagatgga ctgtatcatc aaaatcgctt ggcagtagca
     9661 ccaaatggct caatttcata tatcaacgat acgagtgcaa gtattcatcc tatcactcgc
     9721 atgatcgaag aacgccaaga gaagaaaatc ggtaaaattt attacccagc gccttatcta
     9781 tccaatgaga cgattccgta ttacacttct gcttatgata tggacatgcg taaagtaatc
     9841 gatgtttatg caacggcaca acaacacgtc gatcaaggca tgagtttgac tttattcatg
     9901 cgttctgaaa tcccagaagg catttatgaa tggaagacaa caacgaagca aacgacacgt
     9961 gatttgaata ttttaagaca ttacgctttc cacaaaggaa tcaaatccat ttattacgta
    10021 cgtaccttta ctgatgatgc agaagaaatc ggaagcaatc aatgtgaaag ctgcgtgatc
    10081 taatatcata gatagattcg cttattcata ttttaattaa aggagcattc tcatgtcaga
    10141 aacatattat gaagcaataa actggaatga aattgaagat atcattgata aatccacttg
    10201 ggagaagctg acagagcaat tttggctaga tacacgtatc ccactttcaa atgacctaga
    10261 tgattggcgt acattgtctc aattggaaaa agatacagta ggacatgtat ttggcggttt
    10321 gacactgcta gatactgtcc aatctgaaag tggcatggat cagttgcgta aagatgtccg
    10381 cactccccat gaagaagccg ttttgaacaa tattcaattc atggaatccg ttcatgccaa
    10441 aagttattct tctattttta gtacactgaa tacgaaaaaa gaaatcgaag aaatttttga
    10501 ctggacaaat acgaatcctt atctgcaaaa aaaagctgag cgtatcaatg aaatctacaa
    10561 acacggtaca ccgctagaaa agaaaattgc cagcgtcttt ttagaaacat tcttgttcta
    10621 ttcaggtttt tatactcctc tttattattt aggaaacaac aaattggcta acgtagcaga
    10681 gatcatcaaa ctaatcatcc gagatgaatc tgtacatgga acctacatcg gttacaaatt
    10741 ccaattagga ttcaacgagt tacctgaagc agaacaagaa acgttaaaag actggatgta
    10801 caatcttctt tatgagcttt acgaaaacga agaacgttat acagaagaat tatacgatcc
    10861 aatcggctgg acagaagaag tcaagacatt cctacgctat aatgccaaca aagcattgat
    10921 gaacctaggg atggatccac tctttccaga tactgccaat gatgtcaacc caatcgtaat
    10981 gaacgggatt tcaacaggca caagcaacca tgacttcttc tcacaagtcg gaaacggcta
    11041 tttgttaggt catgtagaag cgatgaaaga cgacgattat ttgattggat tggaataagg
    11101 atttatttta attcaaaaat ttttcgaaaa ataaaaagag tttagcgtac agatatttta
    11161 aatgtacact gaactctttt ttatgcttat tcacttgttt cttccagcac ttttggactg
    11221 tctaactttt ccgaaacatg ttccattctt ctcaataaat agattttccg gatatttaat
    11281 attatcgtct taatcactgc atagacaggt atgcaaatca gcatgcctaa tattcctgcg
    11341 acacttcctg ctccaatcaa taccaagatg atcgtcaaag gatggatatt cattgatttc
    11401 ccaaataaca acggcttgat caaatttcca tctaattgtt ggatcactaa aatcgacaac
    11461 gccatataca aagcttgaaa tggagagata aacaaaccga caatgattgc tggtaccgct
    11521 ccaataaaag ggccgacata cgggataata ttcgtgattc cgcaaatgac cgcaagcaac
    11581 aagctataag gctgatcgaa tattctcatt gccaaaaagc tcattacacc aataatcaaa
    11641 gcatctaaga tcgtactgct gatataggca gataatgttt cgtttaattc ttttaccgtt
    11701 tggcgtaact ctttacgaat cgctttcgga aagaagtgag acaacgcatc aataaatttg
    11761 tgcccatcct tgaacataaa tagcaaaata aatggaacgg taaataacaa aataaaaaat
    11821 tgcatcataa atgaaatgat ttttgagaca cttgcagata aactgactaa tatgatattg
    11881 aacaaattac taagagataa atttgctgat gctaattgtt cttccaaatt gaaattttta
    11941 aactcttccc gctgcgccaa ttcatttaac catttgcttg tttcatctgc atacattggc
    12001 aagctctggg tcaattgaat tgtctgttcc attaactgag gcactacatt catgacagtt
    12061 aaaacaacta aaatgattac gaccaaaaac gtcaataaaa aaccgaacac tctcgggatc
    12121 cgatgctttt cgagaaaaac aacgattgga tcgaacatat aatagataaa accagcaaca
    12181 agcaatggta aaaaaattgc cgaaagcatt ttcaatattg gactaaaaat attcggcatt
    12241 tgtaaaataa agtacacgcc gatgatcgtg agtactagct ccactgtcca gaaaaataat
    12301 tttgattgtt taaaacgtga ttgcatacat ctcctccaag gtcctttgat acttctattc
    12361 tatcatttaa caaagagtta cgcgctgaga ttttcatttg cttaaaaaaa acaaaaaaaa
    12421 taaacatatt ttaatgagta gacgagtact taaacaaaaa cacggtttgg agtagtgaca
    12481 aaaattatac tgcagtccct ttttccaaat aaacggtgtt caaaagcttg catcttcgta
    12541 ataagcccag ccaaacgaaa aatataagga actattttta tttggctggg cttattactt
    12601 gatgtaggac atctatttta caacctcaga tcatttattg cgcaatactg actaaatgca
    12661 actttgtgat atttttgtgt acggacaact cctcgatcac atcggcataa gtgagccctt
    12721 ttggaagatc aatcgtatag atatttttgt acactcggta gtcatcaacg aattttacgt
    12781 caaaattcac atcttcgatt acgatatttt tctcttcaaa ataatcggta agaaaatctt
    12841 tggtttcttt tctatggata aattggattt ctaacttttt agtcgtaggt acatggatca
    12901 cgcgtttcac tactgtgagt gcaatagcaa tcccgataaa actgatgatc gcaatggaat
    12961 agtaacccat gccgatggcg atccctaatc cagcaattgc ccataaagaa gcggcagtcg
    13021 taagtcccgt caccgattgt ttcgtgacga tgatcgttcc cgcgcctaag aaaccgacac
    13081 cactcaccac ttgagcaatc agccttgctt catctgaacg aatcgttcca gcaagctgtg
    13141 gatactctaa agcatctctt aatgcaccac tagcgatctc aacttggatc aatgcaatga
    13201 tacatgctcc catacaaact aaaatatgcg tacgcatacc tgctggacga tttttatatt
    13261 gtcgttcaaa accgattgct ccgccaaata gcatagcgat ccctaaacgt aaaataatct
    13321 ctggaattgt caataccata tcattcatct aaacaccctc cagtccaata tatcatgtct
    13381 gaaaggagca gacaaaaaaa gtgcaatttt tacctcttac gaaaaaagga ctgtgacaaa
    13441 atttttgtca tagtcctttt tatgaataaa cggtgttcaa tcagctgacc ctcggtatta
    13501 ctcaacaaac ggcaaaatat ggggagctat ttttcctttg tcttctctaa tactcaggtc
    13561 aaaacgctga tttcacaacc tctttagcct actattgaaa attacaactt acttgctgct
    13621 tcttcatcga tgatcacaac aacattgtcg tgattttgca atacacttgc tggcaaatga
    13681 ttcgttacag gtccttcaat catccctttg attgcatcag ctttgctttc gccaaatgcc
    13741 atcaagacga tttctttact tttcataatt gaaccgattc ccattgaaac agcttttgtt
    13801 ggtacatctt ctgctttatc gaagaatcgt ttgtttgcat tgattgttga ttctgttaag
    13861 tcaactactg aagtcgttcc gtcaaatgaa gcaccaggtt cattgaaacc gatatgtcca
    13921 ttttgcccga ttcctaagat ttggatatcg attggatgtg catcgatgat ttgatcatac
    13981 tttttgcatg ctgcttccag atcttctgct tttccatctg gtacaaacgt ttctttgaat
    14041 ggttttttat caaataattg gacatccatg aaatgacggt agctttgttc atctgaaccg
    14101 cctagtccaa cgtactcatc taagtttaca gaagtcattt cactgaaatc caaatcgctt
    14161 gaagtcattt ctttatataa agtaactggt gtgcttcctg ttgccaatcc taatactttt
    14221 gcacctttgt tcataccttc tttgatgatt tcaaatgctt tttttccgcc ttcttcagcg
    14281 ttttttacac gaatgatttc catagtgatt gctcctttat attttggtat agcccaatta
    14341 tagcattctt tttttctttt tacaataatt agtatagacc aaattgcatt tttttcattt
    14401 tcttgacaat aaataggaat ccgtgttagg tttcataaga tggttcaatc aaacaatcca
    14461 tgttgcatga aaaccaagca agtgattcac tgtggacgct ttatgtctgc agttttttta
    14521 tgaaaaagga gttattatga gtatactgac attaaacaac attacccagc aatttggcga
    14581 caaaatcctc tatgaaggtg tcgatctgca attaaatgct ggcgaacatc ttgggctgat
    14641 tggacaaaac ggagccggta aaagtacatt gattaaaatc atcactggtg agatcttacc
    14701 agatgacgga cagatccatt ggcaaaaaaa tattcacaaa ggttacctcg atcaatatgt
    14761 ggaagtcgat gaaacattaa caatcgaaga atttctaaaa actgcgtacg caaaagaata
    14821 cgaaaaggaa gaaaaaattg cttttcttta ccaaacatat agcgagacct tcgatgattc
    14881 cttgctggaa aaagctggga aactccaaac ggaattagac caaggagtgt tttatcaaat
    14941 cgacacctta gttgctgaga tgagcagcgg gttggggatc gatgtcttag gtttagattc
    15001 actgttgaaa aatctaagtg gtggacaacg ttcaaaggtg attttagcaa aactactttt
    15061 agaaaaccca gatgttctga tcttagatga accaaccaat cacttagatg atcagcatat
    15121 ccaatggctg acgcagtttc ttcaggattt tgacggtgcg tatatcgtga tttcccatga
    15181 ccaagaattt cttgatcaga tcaccaccca tatcgcagac atcgagtttg gaaagattac
    15241 taagtatact ggccatctaa aacaagcatt gaaacaaaag gaacaaaatc gcgaaagcta
    15301 tttgcgccaa tatcatgctc aacaaaaaca aatcgaaaag accgaagctt atattcgaaa
    15361 atacaaagcc ggttcccgat caacgatggc aaaaagccga caaaaacaat tagataaaat
    15421 cgaacggctg acgcctccag cttcagcaag taaagctgtc tttgattttc cattctcgcc
    15481 tattgtcacg acattagcag tggaaacaac tgatttagtc atcggatatg atcgaccgct
    15541 acttgcaccc atcaatttga ccatccgctt tggtgaaaat attgccattc gaggcttcaa
    15601 cgggattgga aaatctactt tattaaaaac actgatcggt gagattgaaa aaataagtgg
    15661 cgatttccac ttcccagata acacaaaaat caattacttt tcacaagatc tgtactggga
    15721 aaatccatta gaaacaccac tacaatattt aagcagtcaa tttccaaaag cgactatcaa
    15781 agaattacgt cgccaactag ctaaagcagg gttagttaat caattagcaa gtgaacctct
    15841 cactacatta agtggtgggg aacaaactaa ggtgaaactt gcacagttga caatgaacca
    15901 aggtaattta ctgattctcg atgaaccgac gaaccatatc gatcaagaaa cgaaagaaag
    15961 cttacaagac gggatacaga aatttccagg aacagtaatc atcgtctctc atgaacaaga
    16021 attttatcaa gatcttgtgc aacgagtcat tgagattgaa ccaaaataaa cgtttgattg
    16081 aatagttgaa aaaaaggagc tgtgacaaaa gttttgtcac aactccttct tctgaataaa
    16141 tggtggccaa ttagctgacc ttcggtatta gctcaaaaaa cggcaaaata tgaggagcta
    16201 tttttatttg gctattctta ttacttgatg cagaacagct tttcacaacc tcttttcgtc
    16261 tattttttat tttcgagatt tctctttcct ttaaaaacaa ctgtttgaaa gaagaacgca
    16321 catccttgaa aaacaagccc gctaaccgtt acacctaacc agccatactg ctgccacatt
    16381 gtcgtcccta gcaatgaacc agccgcacct ccaataaagt acataaacat aaatacagac
    16441 ccgtggtgct agttaatttt aatatcctaa agaatatctc aaagttcctt caaaacgtcg
    16501 ttgtgctcga
//
LOCUS       DADVXK010000060        16491 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.061, whole genome shotgun sequence.
ACCESSION   DADVXK010000060 DADVXK010000000
VERSION     DADVXK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.061"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(53..1558)
                     /locus_tag="KB909_001835"
     CDS             complement(53..1558)
                     /locus_tag="KB909_001835"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBB6837855.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(1650..2240)
                     /locus_tag="KB909_001836"
     CDS             complement(1650..2240)
                     /locus_tag="KB909_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6837856.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            2419..4065
                     /locus_tag="KB909_001837"
     CDS             2419..4065
                     /locus_tag="KB909_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6837857.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            4114..4833
                     /locus_tag="KB909_001838"
     CDS             4114..4833
                     /locus_tag="KB909_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6837858.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            5312..6259
                     /locus_tag="KB909_001839"
     CDS             5312..6259
                     /locus_tag="KB909_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6837859.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            6271..7191
                     /locus_tag="KB909_001840"
     CDS             6271..7191
                     /locus_tag="KB909_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837860.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            7232..8689
                     /locus_tag="KB909_001841"
     CDS             7232..8689
                     /locus_tag="KB909_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6837861.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            9034..9648
                     /locus_tag="KB909_001842"
     CDS             9034..9648
                     /locus_tag="KB909_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6837862.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            9641..11365
                     /locus_tag="KB909_001843"
     CDS             9641..11365
                     /locus_tag="KB909_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6837863.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            11362..12813
                     /locus_tag="KB909_001844"
     CDS             11362..12813
                     /locus_tag="KB909_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6837864.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(13286..15439)
                     /locus_tag="KB909_001845"
     CDS             complement(13286..15439)
                     /locus_tag="KB909_001845"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBB6837865.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(15441..16487)
                     /locus_tag="KB909_001846"
     CDS             complement(15441..16487)
                     /locus_tag="KB909_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6837866.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
BASE COUNT         5250 a         2939 c         3288 g         5014 t
ORIGIN      
        1 tcacagtccc tttttttctt agaaatggga aaccactagt atataaatac cattattctt
       61 caatcaaccg cttcacgatt gcataatccc cttcataagg ttcatctaca ccattgattt
      121 tttgataggg atccacgcct tttcccgcaa taacgactga atcttgcgga gcgctttctg
      181 ctaaagcgcg tcgaatcgct tcaggacgat ccatttcata atgaacgatc aaatctggat
      241 tagtaattgc ttcattgatt tcttccgcga tttttttcgg atcttcaaat gctgggtcat
      301 ctgccgtcaa aaaggcgatg tcagctgttt ctgatagcac ttttccaaaa tcatgtcgac
      361 gggagattgc tttgtttcct gggctgccta atacaacaat tacacggcca tctggatgtt
      421 catttttggc aaattccagc aatgttttca agcttagata attatgtgca tagtccacat
      481 agacatgcgc tccattggat tggatcaatt gatccattcg gcctggtaca cgagcttctt
      541 ttaatccgtc ttgtgcatct tgactggagg cacctgttag tgctgcggca atgatcgcac
      601 tggctgcatt ttcttggttg aatcctccag ccagcaaaat atcataagca gtatcgcaga
      661 tagctaagcg atcttcatga gaagataaag taaaaccgtg agtaccttta tctgaacgga
      721 tcacttgata attgctttct tccgaacgac cataagtgat cgttggaatc tggaatagat
      781 cggctgtttc cctaagtaaa tcaaaatagt cactttcatg atttaaaaca actgtttttg
      841 aattcaagat caattgtcgc ttgcaataga aatagtcatc aaatgtcgga tgttcgatcg
      901 gactgatatg gtcaggcgag atattcaaga agattccgac atctaaagtc aagccgtata
      961 cgcgttgtgt tttgtaagct tgtgaagaaa cttccatcac tagatgagtc ataccatttt
     1021 caactgcttc tgacatcata cgatataaat ctaatgactc aggcgttgtc aaatgggatt
     1081 tgaaatatgt tttgccatct aacgttgtat tcatagtaga aagcaatgct gtttttttat
     1141 ttgttgtgtg atccaagatt gcttttgtaa agtacgcagc agttgtttta ccttttgttc
     1201 cagtgaatcc gatcactttc aatttatttt gcggatagtc gtaaaaagcc atagcaagaa
     1261 gcgccattgc tttacggata tccgttacga tgattcctac tgctgaattt tcgtatggtt
     1321 gttctgatac ataatattga ataccctgtt cgattgctga atccaaatat tcttctttga
     1381 aattcattcc tttacagaaa aacaaagtag aagcatcagc ttttcttgaa tcataactta
     1441 actgaagaaa ttcagctttt tctggtacat caagatgcca gcctcttgtt gaaacaaatt
     1501 cttttaatag attttctttt aatagtaaat gacggatgtc ttctaaagag aagctcattg
     1561 attgatccct cgctttattc aatttcttgg tttattatag cacactcttt ttaatatatc
     1621 gtttgtttcc gctatgacaa aatccagctt tattcaaatt ttcttgacac aggggacaag
     1681 cggatgagta ttttcataaa caatgaactg actgtaatag ataggagaac gaatagtgtc
     1741 tccaacaatc caaaaacata ataattcaaa aagacgataa gactattggt aagtaaaagt
     1801 ccttgcggca ttggaagccg aaaaaatttg tggaaaataa tcggcggtat cgttataccg
     1861 ccatttgagg ccccgactgt gtacaatgtg taaaccccaa gactgaacaa aagacttcct
     1921 gaaatcagtg aaaagaaatg tgaggagatc atttccactt ttggaacaat ctctaaaaca
     1981 acaggaaaaa gcagacttcc cgctacagtc ttaaaaaata ctgattttcc taataggaca
     2041 gcggctagaa gcagcatcat aagattgatg ctccaaacag taactgagcg ttggatagaa
     2101 aaggccgttt caactaaatg tccgatggcg cccactccgg cggaagctat atcgtgaggg
     2161 agcaagaacc aattcaatcc aactgtgata aagaaaagac ctaaaaatat aacgggtagt
     2221 ttttttattt cttgtgtcat tgatatctcc tataaatgtt agccataaaa ggctgtatat
     2281 ttctttactt taccaaaaaa acgaaaccga attcaaaaaa acaattgttc ttataaaagt
     2341 tatataaaat cgattgccag tttctgtttt accaattaaa atgatagtaa tgttttgtag
     2401 aaagttggaa tctgaccgat ggataatcaa agaaaaccag cattagatca attaacaccg
     2461 caagaaaaaa tggcacgagg ctctgcttgg atgaccgcca gtaatatcat ttcaagattg
     2521 ctaggcgctg tctatatcat tccctggtat gcttggatgg gcgaaaatgc taaggctgcc
     2581 aatggattat tcaatatggg atacaatata tatgcattgt ttctactgat ctctacagca
     2641 ggaatacctg ctgcgattgc aaaacaaact gcacgctata attcattgaa tgaatatggc
     2701 acttcacgac gattatttat ccgtgcatta cagatgatgg gcgggctagg cctgttgttt
     2761 gctttgttca tgtacatcgc ctctccttgg ctagctcatg cttctggtgg cggagaagaa
     2821 ctgattccaa cgatgcgttc tttgagtatc gctgtattgg tttttccttg tatgagtgtg
     2881 atacgagggt attttcaagg caatcaagaa atgatgcctt atgcgctgtc gcagattgta
     2941 gaacaggtgg cacgtatttt ttatatgcta ttggctacat tcatcatcat gaaagtcatg
     3001 gatggtgact atgtgacggc ggtcacgcaa tcaactttcg cggcatttat cggtatgcta
     3061 gcaagtattc ttgtcctttt gtattttttg aagaaacatc aagcgtatac atcggcgttt
     3121 attcactaca gcgaaaacaa aataaatatt gcaacgaagg aattgttgtt agataccgtt
     3181 aaagaagcga ttccgtttat tattgtgggt tcaggggtaa cgatcttcaa attagtcgat
     3241 cagttcactt ttatgaagat catgtctgca tccaccgagt attccaatgc acagttactg
     3301 gatctttttt cgatttttag tgccaatcca gataagttga cgatggtagt tattgcattg
     3361 gcaacatcga tcgcgtctac tgggttaccg ttgattacag aagctgttac gttgaaagat
     3421 cgagtaggtc tggcaaaatt gacaagcgga aatttacagt tgttttcatt ttttatgttt
     3481 ccggcgacat ttggtgttat gttacttgcc tatccgctaa atacattatt ttatacaccg
     3541 gattctctag gaagtaatgt actgatccaa gcaagttttg taggactctt cctaggacta
     3601 tatatgctag tttccaacat gctgcaagga atgtttgaaa acaaggcggc aattaattat
     3661 ttggttattg ggtttctagt gaaactcctt cttcaatacc cagccattcg tttatttgaa
     3721 gtatacggcc ctttattggc gacaatgatc ggatttgctg tgtcttgtac cttgatctta
     3781 aagagaatcc atgaagtagc ccgctttaaa ccaagttttg tctggcgcag gacattgctg
     3841 atctttattc ttaccttgat tatgcttttg gcttcgtgga tcacaaagat gatttttggt
     3901 gcttttttaa acgaagatag caaattccag tctctattgt tgattcttgt agtagcaggt
     3961 ataggggctt tagtgtatgg ttatttagct ttgaaaatcc gcttggcaga aagactacta
     4021 ggaccaggaa tagcgcgttt acgacataaa ttaaaaataa aataagtgaa tcagaagagc
     4081 tagattgatg ctcttttgaa atgggggaaa cgcatgcgtt tagataagtt tttagcagat
     4141 atgggacttg gcagccgcaa agaagtcaaa ggattgatca aaaaaggaac gatcgaagtc
     4201 aatggacaag tggtgaaaag cgataaagcg caagtaaatg aattcgaaga tgcggttact
     4261 tatttaggag aaatcattac gtatcaaaaa gatttttact acattttgca taaacctgca
     4321 ggagtcattt ctgctactca ggataatcat gatcaaaccg taatcgattt attggaagac
     4381 caggattatc gggaagatct ttttccagtc ggccgattag ataaagacac agagggcctc
     4441 ttgattttaa cgaatgacgg ggtgtttgcc catcagttac tatcacctaa aaaacatgtg
     4501 gagaaagaat atctagctga ggttagcggt ataatgacag aagaagatat ccgtttattt
     4561 gcagaaggac tgattattga tggcgatgag cagacattgc cggcaaaact ccaaattgat
     4621 caagtagatc aagagacaga aacttcaatt atccgtctga ttttgcatga aggaaagttt
     4681 caccaagtta agcgaatggt caaagcagta ggaaaagaag tcttatattt aaaaagaatc
     4741 cgtatgggaa aattttggct gcctaaagat ttgaataaag ggcaatatcg acccatgacc
     4801 aaagaagagc tagaacaagt gagagaaaaa taattgaatg gatagctaaa agaataagca
     4861 gagtagttgt agcgccatct gaaaagcaga cttgtccgtc tgactttcgg atggcttttt
     4921 tgtgaaattt cggcttattt ccgtagaagc tacttctgga acaccgtttg ttcggaataa
     4981 gggactgtga caagactttt gttacagtcc ccattgttcc ttgtgactca gagttagata
     5041 gtaaggacac gatctcccta atactcaggc caaaacgctg aattcacaac ctctgataaa
     5101 cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta
     5161 ttttcccgtt tttttctcta atactcaggc caaaacgctg atttcacaac ctctcctata
     5221 ctttgtttca ttttccctat actttgttta tttattctca ttattgaaag cgctataatt
     5281 acgttgcgaa tgaatcgaaa ggggttttta gatgaaaaaa cgaaaggggt tcaatcattt
     5341 ttttatgaat ctatggcgtt ataaagcact tgtcctgatg gctgtaccgg gtatgctttg
     5401 gatgattttt ttcttttaca tacctgtaat ggcgaatgtc gtagcattca aaaattttca
     5461 tatttcagca gatgggttct tggctagctt gagggaaagt ccttgggtgg gttgggaaaa
     5521 tttcaaattt ttattttctt cggatcaagc atttctcatc actaaaaata caattttata
     5581 taatgtagca tttatccttt tgaatctgct gatctcagtc gtatttgcaa tcattatgag
     5641 cgagttgaga aataaacgac tcgttaaagt ttatcaaacg atgtccttac taccttattt
     5701 tctatcttgg gtcattatca gttactttgt ttacgctttt ttaagtcctg acaaaggaat
     5761 attcaatcag tggatcactg gacatggagg agaagctgtc aattggtata atgaaccgaa
     5821 atattggccg tttatcttgg tgttcattgg tacatggaaa gggattggtt ataacagcat
     5881 tatttacttt gcatctgtta tgggaatcga tccgacttat tatgaagctg ctatggttga
     5941 tggagctagc aaatggcagc agatcaaaca tgtgacgata ccacaactta ttccactaat
     6001 gacgatttta acgattttag ccgtaggaaa cattttccga gctgattttg gcctgtttta
     6061 taacattcct aggaattccg gtgcattata tgatgtgact caagttttgg atacgtatat
     6121 ctacaatggc ctgacatcca caggagattt tggtatgacg gctgctgcag gactttacca
     6181 atcagttgtc ggctttgtct tgttgatgat cacaaatacg atcgcccgac gttttgatag
     6241 cgattctgca ttattctaag gaggaaaaaa atgaaaaaaa agaaagtgga gagagtccaa
     6301 gtccgctctt tcaataagac ggctaatttt ttctctaata taatgattgc actctttgct
     6361 atttcctgta ttttgccatt tatatttgtt atcgccatct cttttaccga tgagtccata
     6421 ttgtcgactc acgggtacag tttttggcca gaaaagttca gtatatttgg ttatacgtac
     6481 ttgttcgacc agatgcagga taaaattttc caagcgcttt tcgtcactgt acttgttact
     6541 gttttaggta cactgatcaa tagcacggct acttctttat atgcttatgc gatttcacgg
     6601 tcaaactttc cattccgtcg tttttttacc gttttttgtt tgattacgat gttgttctca
     6661 ccagggatgg tggccaatta tcttgttatg acaaatcttc ttcagttaaa agatacgatt
     6721 tgggcattga tcttgccaat ggctgtcagt cccttcaata ttattgtgat gcgcacattc
     6781 tttaaacgtt cggtctctga ttcgattatt gaatcggcac ggatcgatgg agctagcgaa
     6841 ctgcgaatat ttgttcagat cgttttaccg ttagctgttc caggtattgc gacaatcagt
     6901 ttatttgccg cattgggtta ctggaatgac tggttcaatg ctttactata catccaagat
     6961 gataagctag ttccactaca gtatcttttg atgaaaatcc aaagtaatat tcaatatctg
     7021 acacaaaatt caggagcagg aagccaattg acaggcggat tagcctcagt tccaggagaa
     7081 tctgccagaa tggcgatcgt agtcatctcg acgttgccta ttgcgatcag ctatccattt
     7141 ttccagaagc attttgtcaa aggtctaaca atcggcggag taaaagaata aagaaacaaa
     7201 aatataaatc ataaaattag gaggaagaaa aatgaagtta tggaagaaac tagcctttac
     7261 aggtgtttca gcgttgttgt tgggaacatt agcagcatgc ggaggttctg gttctaaaga
     7321 ccaggcagaa gctagcaatt cggacacttt gcagatgtat caaatcggag ataaaccaga
     7381 taatttcgat caattgatgg aagtagcaaa caaacgaatc gaaaaagaga tcggtgtaaa
     7441 agtcaatatc aattacattg gctggggcga ttacgaaaag aaaatgaacg tcatcatttc
     7501 ttccggggaa aattatgata tcgcctttgc gaacaactat gtttccaatg cccaaaaagg
     7561 agcctttgct gatttgactg aattagcgcc taagtacgct gaaaaagctt ataatgattt
     7621 agatgaagca tatattaaag gaaatctggt caatggaaaa ttatatgctt tcccagtcaa
     7681 tggaaatgtc tttgctcaac aagtacttac ttttaacaaa gctttactag ataaatacga
     7741 tctttcaatt gatggaatcc aatcttacgc tgatgcagaa aaagtcttga aggaattcca
     7801 tgaaaaagaa ccaaacacgg cagcttttgc cattggacaa ggcttcaaag tccaagggaa
     7861 ctttgattat cctttaggga atacgttacc atttgctatt gatctggatg gagatgattc
     7921 gaaaatcatc aaccaatacg ataatgaaac gtatatcgga ctgttacgta caatgcatag
     7981 ctggtacaaa caaggactca ttccaagtga cgctgcaacg agcaataagg attatccact
     8041 agaaggaaat acttggctaa tgcgtggaga aacacaagga ccgtatgatt atggcgatac
     8101 aattttgaca aatgcagcaa aacaagaact tgtctcaaaa gcaattactg ttccactaaa
     8161 atctacagct caagcacaaa tggcaaattt tgtcgtatca aatacttcaa aaaataaaga
     8221 aaaatcagta gaacttctag ggctgcttaa cagtgatcca gaattattga atgggcttgt
     8281 ttgggggatc gagggagaag catgggaaaa agtcgatggt tcagatgata aaatcaaatt
     8341 gctagatggt tatcagccaa atacacatat gtctgcttgg aatacaggaa acaacaagat
     8401 tctatataca caagagtcta ttacggatga catgattgcc aaacgtgatc aatcgattgc
     8461 tgatgcagaa acttcaccga ttttaggatt cagcttcaac actgacagtg tcaaaacaga
     8521 attaagtaat atttctaatg tcatgaatca atatttagat ggattgaata cagggactgt
     8581 tgatccagat gaaacattac cgaaattgaa agacgctttg gacaaggctg gctatgataa
     8641 ggtattgaaa gaaatgcaaa aacaatatga tgagttccga caagaataat aatgaataaa
     8701 gacaaagggg ttgtgacaaa agacgtgtca caacctcttg ttccgaataa acggtgttca
     8761 aaagccagtt tctcggtatt aagctaaata tatgtaaaaa tgtggaaagc catattcaca
     8821 aaatttttct tactactcga aactaagcgg ctatttcaca aactcttggt aaacggtgtt
     8881 caatcagcta accctcggta ttcgctcaca aaacgacaaa atatgaggaa ctatttttcc
     8941 gtttgtttct ctaataatca ggtcaaggtg ctgattgccc aacctttttt tgtataatga
     9001 gaaagtataa acttaatgtt tggaggagaa gatatgttag ggaaggtttt ggaagagtta
     9061 tttatccgga tctgggtcat tataaaacta accttgtatt tctggatata tacatttgcc
     9121 ggcgggatca tctttggatt aggtgcggca tggaaaacag tcaatgaact attttatttg
     9181 tacggattcg agtataaaga aatcacaata aaaagaggct ggaatatata taaaagaaat
     9241 tttttaagag gcaatctgct atttagttta tttttatctg gtactgcttt attgagttac
     9301 aatttatatt tatctgttca aatcaaaggg ctcatttttt tagctattga ttttatttta
     9361 ctttttgcct tgctctgcct atttgctact tatcaataca gtatgatttt agatagtgaa
     9421 tatacgatct ctgttcctaa tctgctaaag ctaagtttta tttcggtttt ttccagcttt
     9481 tcgtcttttc taaaaataat tattggtagc ggtataattt taggcgtgac ttggcaattc
     9541 aaaggattga tcctgtttgg tgtcattggt cttttgacgg tttggaatgg tacgatgaca
     9601 acacattggc gtgaagaatt agataaacag ttggaaagtt atgaataagt ttcggattct
     9661 attttcaaaa ggaaccttac taaatcgtct gttgcggaaa tacgcggtta tcatgatcgg
     9721 tgtaacgatg actgctaccg ttatttttag tatccatact tgggaacaaa atcaaaaaca
     9781 ggcagaaaac atgacaagtg atgccgttca aagcacaagc agaatgctga atgataaaac
     9841 aaccttgagt aggatcatca aaaaccagct tgtagggaat tccgaaaaga tcgaaaatgt
     9901 gacgacctac ttaacaaaac ccatagatca gtatctgatg tatgtatacg aacagcaaaa
     9961 cagtaccgat gaattagttt ctttcccaaa tcaaatcaaa gatctctacg caaattatga
    10021 agaactaagt gcgatatata tcgtgttgaa tcaactaccg gagtattatg aatcttctag
    10081 agaaaacaaa ggtggggaaa taaaaaaggg gacaccaaaa ttactagacg ccttttatat
    10141 caagttgcct atcacacaag gaggagctga gtcaggaagt atttttattg gttttcaaaa
    10201 gaaagaacta gatatgattt tagaaaatct aacgtcattc aatggactct ctttatacat
    10261 gatttctgga acgacaaatc gactatacac attccatgat aataaaatag ctaaagaaac
    10321 gtttgaaaga caagaaatga tcatcacaga gagtctgaag aaaaattcac aattgccgat
    10381 tgacgatctg gaaaaaaaca attttgttca acaccaagaa ctgtctgatg attatcgtat
    10441 attagctgta ctagataaaa aaagtgtaaa aatcgaaacg ggaaaaaatc ttgccccgct
    10501 gatcattggt atcattattt tagacaatat actgcttatc tttctttata aaacattcaa
    10561 acgatattca cagcaagtat ctatcgtcat gcaggccatg gatcaaacag cagcagggaa
    10621 tttagagacg cggatcgaca taacaaacac ggaatatgaa ctgaaggaac tttcaatcgg
    10681 tatcaacgaa atgttggata gcatcaatca gtttgtagaa gacatctaca aattagaaat
    10741 caaacagcaa gacgcacata tgcgggcgct tcaagcacag atcaatccac actttttata
    10801 taatacatta gaatatatcc gaatgtatgc aatcagcgaa ggaagtgaag aattagcaga
    10861 tgttgtgtat gcgttttccg ctttgcttcg aaacaatacg aatcaagaga aaacgatcac
    10921 tttaaaagaa gaactggact tttgcgaaaa atatgtctat ttgtatcaaa tgcgttatcc
    10981 taatcgagta gcctatcatt ttatgatcga tcctgatttg gaaaagatcg aagtacctaa
    11041 atttgtgatc cagccattag ttgaaaatta ttttaaacac ggtattgatt ttactcgatt
    11101 cgataatgcg ctaagtgtca aagtcttgca ggaaggcaaa cgggtaagga tcatcatcaa
    11161 agataatgga aaagggatga ctgaaaaacg gctaaaacag attgaagaaa aactgtctca
    11221 tcctaaagtg gaacttcacg gttctatcgg tctgcaaaac gtgaatgaac gtttacgtgc
    11281 cagcttcggc agcagttatt atatgtcgct tgagaataat gagacaggtg gactgaccgt
    11341 ttctattaca ttcaaggagg gatgagcgtg tatcaagtgt tattggtaga tgatgaatac
    11401 atgattttga atgggttaaa aaagataatt gattggcaaa gtttaggctt tcaaatagta
    11461 gcaacagcag agaatgccaa agaaggacta gctgtacttg aacagcgaca gattgattta
    11521 gtagtaacgg atgtgacaat gccagaaata aatggactgg aatttattga agcggctcaa
    11581 aaagaacgtc ataattttga atttatgatt ttatcaggat accaagaatt cgattatttg
    11641 aaaggaggta tgcaattagg cgccgtgaat tatttgatga aacccgtgaa taagttcgaa
    11701 ttggttgaaa gcctcaagaa aatcaaaaca cggttagatc agcaaaatga acaaaaaaat
    11761 caacaagaaa tctatcaaga actgttattc agtcaatggt tgaatgaaga attggatgaa
    11821 ataagtgaag aagaaataat aggacaaata agtgagaagc agcataggat agtattgatt
    11881 caactggcaa gaactcatga tactcttatc aatagatggt tgcaagaacg gcaacaaatc
    11941 ttttactatc aacgaaatta cggagaccgt gtattgatca cgttgttgtt ggaggcagat
    12001 gaagttgatg gcttctgttg ttttgttcaa gaaaactttc ctgatcagga atggctgatc
    12061 agtatcgggg aagagacaga ttctttggac aaaatccctg aaacattcca acaagcgaaa
    12121 gacaatctac agttgcatca attttatgga gataaagacg agcatgtttt ttacgcagta
    12181 caagcagaaa caaaagatca aaccatcgat ttttcaagtt tcagacgcgt gctgcaaaat
    12241 aaacaattgg aagtcgctca aaaaatgatc actgattttt ttgaacagtt tcagttagca
    12301 gccatgatgc cggaagatat acgatattcc agttttttac tgtttatgga gattcaacgg
    12361 gaattgattg atctggaaga tgaggaatat ttacaaggaa tcgaaaaaat ccatcaggca
    12421 aaaacggtgc aagaacttca gcagctactt ctgtcattca tcaaaaagca tcagagacag
    12481 aaaaagtaca gtgacaatgt ggaaaaagta atcgtaatcc tgcaccagca ttatcaagaa
    12541 ccacttacac tcaaagaagt gtcagaaaac ctgcatttaa atgtcatgta tctaggacag
    12601 ctgttcaaaa aagaaacgaa aaaaagtttt tcagcttatt tgaaccattt acgtatggaa
    12661 aaagcgaaac aactgctttt gcacagtaat caaaacatca atgagatagc aagtgagatt
    12721 ggctacaaca acaccacgta tttctctaaa ttattcaaga aaatcgtcgg cagatcccct
    12781 aaagagtacc gagaaaacag tggagaatca taaaaaaaaa agccaatgta atgaaataac
    12841 ttataaaaaa ttgtctagaa atctaatttt gggctgttct tattacttga ggcaaggcag
    12901 ctttttcatg acctctcgat aaacggagtt caaaagccag tttctcggta ttaagccaaa
    12961 tttatgcaaa aatgtggaaa gccattttca caaaattttt cttaatactc gaaactaaac
    13021 agctttttca cgacctctcc actaaatggt gttcaatcag ctgaccctcg gtattagctc
    13081 aaaaaatggc aaaatatgag gaactatttt gccatttgtc tctctaatac tcaggtcaga
    13141 acgctgattt cacaacctct caataaacgg tgttcaaaag cttgcatctg cggtaataag
    13201 accaaccaaa cgaaaaatat gaggatctat ttttgcttgg ctgttcttat tacttgatgc
    13261 aggacagctt tttcacaacc tcttgttaat tatagtttga taaggaaaaa ggcaaatctt
    13321 ttgcttgata tttcttaggg tgagggatga tccctaattg gtaagagatc gtgccgcctt
    13381 tcagcaaatc ttgatgggta aaatataatt tcgtatattc tctgtccatc cgtttgattt
    13441 tatggataaa ttgttgctgc ggccgattag gcgttgcttc aatcgtcaat tcctttccat
    13501 ttgacaaaag caaaacagcc ttgtcaatta atggcatacc gataacatat tcaccggttc
    13561 caggcgtgac aggataaaat cccagactat tgaagatata ccaagcggcc atacttccat
    13621 tgtcctcatc tccagggtaa cccattggag aatcgtcgaa ggtctgagtc atcaactgtt
    13681 taagcagtgg ctgtgccatt tcaggttgtc ctatataact gaacaagtaa ggatagtgaa
    13741 aacttggctg gtttgaaata gctaattgtc caaattctat cgcggccatc tcactcattt
    13801 cgtggatctc aaaaccatat cctcctgggt caaacgttgg gggctgattg cacagctcaa
    13861 tgagtttttc tttatatctc tcactgccac catattttcc gatcagtcct gaaaaatcgt
    13921 gataaacagc aaagctgctt tgccaagcac ttccttctgc ataatcttgt ccccaacgat
    13981 tagctgaaaa tggttctctg aacttgccat ctttatcttt tgaacgcata aatcctgact
    14041 catagtcaaa gatattttga tagttcaatg attgctgctg atatttcttc gtcatttcct
    14101 cttcttctag taccttggca acttggctaa tacaaaaatc gctataagca tagtctaatg
    14161 tgtgattgac tgattcgtgg tagtgattag gaacatagcc atatgtcaag taatcttctg
    14221 ttccttggcg tccataattt ggatgtttgc tttgaaccgt agcacctttt tccattgccg
    14281 ttagaaattc aggcatcaag tctcgtcgga tatcttttac agcagcatct gcaatgaccg
    14341 catcgatcaa tgtcccaggc ataagtccac gttcatcagg agacagccat tttggcaaat
    14401 agccactttc tctatagctg ttcaaaaaac cttccagcat ttcttcgtat ttttctacag
    14461 caatcaaaga ataaagagga taaaccgttt tatacgtatc ccaaaaccca ttatttgtat
    14521 agagaacacc aggttttata gatcgactag tcgtatcata gtggattttt tgcccactag
    14581 gatcaatttc ataaaatgtt tgtggaaata aaaacacccg atataaatta tgataaaacg
    14641 tccgcaattg ttgttgatca tggtgtgtga gctgtatacg atcaaaatag gactgccatt
    14701 gttcttgact gtgagcaagg taagtctctt tgctttggtt ttgttctagt tccaggttat
    14761 aagctgcttg ttccgagctg ataaaagatg tcccaaatcg gatagtttgt ttttttgtct
    14821 gttcaaaata caacgggatc gagtcgctat ttttgttgga aacagctaac tcatcaattg
    14881 ttaaaggata ttcaaatctc aatataaaat aaaaagaaaa atcaggatct tctgaaccag
    14941 caaaatgtgt gatttttcct tccactgtgt aaggatctat aacaaagagc tgatggcgtc
    15001 ccggaaagga taaaagtaaa ccgctgtcat ttttgctgta atcaatagat aagattccgc
    15061 catacatgct aggtatcaat gtagaacaga tgccataacg taattgacag atcgacagat
    15121 gagtcgggca aaatatactt tcttctgggc ggtaagaact ttgagcatgg aaaagggtgt
    15181 tctcctgtag ttttccattg atcggcgtaa acagcatatg actgaaatca cccatccaag
    15241 gacttggttg atgggtaaga cggtagcctt gaaaaacgcg gtcatcagga tgaaaccacc
    15301 agctgccgtt ttgatccgta gtttgcggtg caaaataatt catcccaaaa ggaacgccag
    15361 tataaggctg gcagttccca ttagagaaat ttggctgatt cgctgttgca tgtctagtat
    15421 ctatttgacc gatattcatt ttatttctcc tttgttgatt gtcttttgat gaatgaaact
    15481 ggaaatttac tatcggatgg tcgatctttt gtctctaacc aagtgaccaa agcatctccc
    15541 gcaagcttac ctaactgttc aaaatcttgt gcgatggttg tcagtggcgg gtcaacaaga
    15601 gctgctgctt ggatatcatc aaatccgata attgaaaaat cttcagggat atgataacca
    15661 tgctgtctca agagattcat ggtctggata gcgacaacat cgttttcaca aacaaaagca
    15721 gttacttcat acttagtgat ataagaaagc aattcatcta atgtcgcgct tttgtcatcc
    15781 agtgaagtgt ggaaagtcaa accagctttg tccaatgctt caaggtaacc aaggtaacgc
    15841 tgtcgaacgg attgtggatg agtctgcgta ccaaacaaat aagcgatttt tgaatgtccc
    15901 tgttcgatca aataagaggc agcaagcgca ccgccttgga aattatcgga aagaacggta
    15961 ggaaaaggta actcatagat ttttttatct aatatgacga cagggaattc tttcaatgaa
    16021 agctcaaaaa gtaagtcaag atgttgttct gtatcaagag cataataaat caatccgtca
    16081 aattcattga ttagctcttt tgctgtttta ttttgtagaa agtcaagcgt cgtcatcatg
    16141 acatcaatct gtttatcttg catcacaggg ttcaatccct tgctaaaatc accaacagac
    16201 aaatcagcga catatggaag aagaaacaga atccgtcgtg tttttgtagg agaagcaaga
    16261 atctgttccg gagaagcgga tttaacgaaa ctgcctttcc cgcgaacgcg ataaataagt
    16321 cctaattgct ctaattcagt caatgcacgt ttggaagtga ttctgcttac tttataggta
    16381 cgtgaaagtt ctttttcagt tggtagttgg ctgtctacag gtaattcacc agttaaaata
    16441 gccgtttgca aatcattaaa tattgtctgg tacaatggtt gagtcatata a
//
LOCUS       DADVXK010000061        16392 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.062, whole genome shotgun sequence.
ACCESSION   DADVXK010000061 DADVXK010000000
VERSION     DADVXK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.062"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(51..1598)
                     /locus_tag="KB909_001847"
     CDS             complement(51..1598)
                     /locus_tag="KB909_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBB6837867.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="KB909_001848"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="KB909_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBB6837868.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="KB909_001849"
     CDS             complement(2043..2237)
                     /locus_tag="KB909_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837869.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(2463..3665)
                     /locus_tag="KB909_001850"
     CDS             complement(2463..3665)
                     /locus_tag="KB909_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6837870.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(3668..3862)
                     /locus_tag="KB909_001851"
     CDS             complement(3668..3862)
                     /locus_tag="KB909_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6837871.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(3909..4757)
                     /locus_tag="KB909_001852"
     CDS             complement(3909..4757)
                     /locus_tag="KB909_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBB6837872.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(4962..5312)
                     /locus_tag="KB909_001853"
     CDS             complement(4962..5312)
                     /locus_tag="KB909_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837873.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            5907..6353
                     /locus_tag="KB909_001854"
     CDS             5907..6353
                     /locus_tag="KB909_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6837874.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            6977..7969
                     /locus_tag="KB909_001855"
     CDS             6977..7969
                     /locus_tag="KB909_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6837875.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            7985..8869
                     /locus_tag="KB909_001856"
     CDS             7985..8869
                     /locus_tag="KB909_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837876.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            8918..10525
                     /locus_tag="KB909_001857"
     CDS             8918..10525
                     /locus_tag="KB909_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6837877.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            10526..12010
                     /locus_tag="KB909_001858"
     CDS             10526..12010
                     /locus_tag="KB909_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBB6837878.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            12187..13179
                     /locus_tag="KB909_001859"
     CDS             12187..13179
                     /locus_tag="KB909_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6837879.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            13231..14100
                     /locus_tag="KB909_001860"
     CDS             13231..14100
                     /locus_tag="KB909_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6837880.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(14520..16085)
                     /gene="guaA"
                     /locus_tag="KB909_001861"
     CDS             complement(14520..16085)
                     /gene="guaA"
                     /locus_tag="KB909_001861"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6837881.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(16140..>16392)
                     /locus_tag="KB909_001862"
     CDS             complement(16140..>16392)
                     /locus_tag="KB909_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6837882.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         4956 a         2866 c         3325 g         5245 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttgaaaaacg ttgatttatc
     2341 ggcattcccc atccatatta tatttacgtc ttattcccac tcaatatgag tagcctcgta
     2401 aagaagctat tatatcagtg ctttttcagc ctattcctca ttttggtagg gaaatggtag
     2461 ggttagattt ttactgcttg atttccatta aagtttgcaa ctttagattt tgttgcacag
     2521 gtaaatttaa tgtttcctgt catttgttct gcaattcctt catcattacg gctccataga
     2581 tgagcgtagt gctttaaagt gatttcaggg ctagaatggc ctaaccgttg cgacacgacc
     2641 agaatgtctg cgttaaactc attgattagg tagctaacat gagaatgacg taatcctttt
     2701 ccttgtatta ggggtacctt agctagtttg gcataacgct gaataattcg ttgaacagtt
     2761 gaacgataga gtgggaggtc agtgtagcta agaataaatt gttctacacc atgatttttt
     2821 tgaataactt tccacttttt tagcacttca attgtatcat cgtccagaga aatgatccgc
     2881 aagccgcttt cagtttttgt gtaaggtttc cgaataaaat ctttttgatt tgtcatttcc
     2941 aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca cgtcattcca attaagtgct
     3001 aatccttcgc ttacacgaac accagtcatg taatatagcc agatcattaa aaaacacata
     3061 tgttcgtaga aatcatcttt ataaattttt gccaaaactt cttcaaattc ttcttttgtc
     3121 cagtaaggaa cgattgattt tccttttgga attgcttttg ttcttttgga aatattctca
     3181 ttcagaaatt gcagggtgac cgcatagtct aatgatttac gaaacatacc gtacataagt
     3241 gaactgtatg cttgtgagta tccgctatcg ttcaataacc aaattcgata attttcacaa
     3301 tctcgcacat tgatttcacg aagcttctta tcaccgaaaa attcagtaat ctgaatcaat
     3361 ccacactcac gagaactcca agtacttttt tgtacgctag ctttgtagtg tggaacgtaa
     3421 gactgctcca taaattcttt gtaagttaaa tcataattcg caaatccatt tacaaccatg
     3481 tattcatttt ttatacgcat gacttctttg tgtgcttcac gagctgatga gaatcgtttt
     3541 cctagagaat cttttgttcc tttcttctgg atcctctttc cagtcacttg atctgttcct
     3601 aactcaacta gataagaaaa gcgaccattt ttatcttgat acacacaagg gtattttgtt
     3661 ttcatagtta ttcctcctgt gaaagaggaa cacctataat ttcttcaatt acttgtcggg
     3721 gtactacccc aactctttta ttattataat atggatatcc ctgatttacc attcttgttt
     3781 ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa tcctagagcc tctaaatctt
     3841 ttcgacaaat tgtatttttc attgtataaa ctcactttca aagaaaacac tatcattggg
     3901 taatagtgtt atttctttat ttttgtataa tgaacggtac tttcttgaaa atccatcact
     3961 tgttcaggac ttcccaactc atttaaagct aaagcattgt aaaaaaatgg acgtctaact
     4021 atatattcgc ttgtatatag tatatcttga ttcgtggaat catagggttt ctttaccatc
     4081 tttttggtga cagttggtag tttgagattc cgggacttga aaaaagcttt tttcttatgc
     4141 tctttcaatt ccagctcttt atcgaaatat ttgctgatat agcgcccgcg attttcgata
     4201 ctgtctacat cgatcttgtt gatcttaacg aaaccctgac cccaaatcgt agttaaccgg
     4261 ttaaatgaga taaaggggaa atcaaacaag ataatatggt agtggattgc accgcgttgc
     4321 tgcttttccc acgtggcgag atactttaaa tttgcttttt tagttttata gaggtcataa
     4381 ttcagtcgtt tgataaattt tttaaattca ttatttgcat actcaatgtc ttgaatgttt
     4441 tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa aattcgtgtc tacaaggcgg
     4501 gcaatctcaa atcgcatact ttgataatgt ttctgtttgc gttttaaact gtcatattgt
     4561 ccttgagcgg ataattcatc atagtttttt cttttttcaa gagtaatatc attttcataa
     4621 atccaagcta atttttgttt tcgttccaga tttacttcgt tttcgatcgt tttacgtttg
     4681 ggagtaatga ttgcttcata atcataaatt tcaatatacg tgggagtttc aatgattttc
     4741 tgattataag cttgcaaaaa tcatcactcc ttgttgcgta ttcgattgtc aaagaaccag
     4801 tcattttctc ctgatgttga tctataaatc aagttaaggg ggaaggcctg cgtagcagcc
     4861 cttctagcct atggggtgtt gggcggtctt aacggacaga aacggctctg tgggcgctgc
     4921 cccgccgttt cgtcctaacc acccaacact ccatagtata gttagttttg tgtagtggta
     4981 ccttgttttc tgggaatcaa agttgccgta tcagcggttg ccgataaccc ataactgaca
     5041 aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat tggtaaatgt aattatggct
     5101 aaaccttgtt gggtaagttc ttccggcgtg atcacaggat gttcagattt gactttgaca
     5161 ctgatttttt cgtagcgaag ttttggtagg atacattcgt agctccaacc tagaatttcg
     5221 ccctcctttt gccagcgagt gacattgacg acttggtatt ctttttcgag tgtttctttt
     5281 ggtaaactga gatcggtaat ttttattggc atcacaattc tcctttttta tacgaaagtt
     5341 tatacgattt gattaaaaaa tatagatggc catctacgac ttgtattata tacgagaact
     5401 tatacgtagt caagagattt tctaaaaaaa tatatacgat tttttatacg agtgttataa
     5461 tgaaaaaaat gataaggagg aatttgaata tgtttggttt agtacaacct aataaagtga
     5521 aggtgggcca acgaatcaaa gaaataaaag acggaatgtc tctctctttt acagaattag
     5581 ggaatcgatt aggtttaaaa aagccgacga tcagttccta cgttcaaggc tatgcgttgg
     5641 ctcctaagag tgtgatcaac caattatcta gtatcagcgg aaaacctgtc ggctggtttt
     5701 attttgggca tgtggaagaa tatatccgag agtatttgtt tctcattggt cagaaaaaaa
     5761 tagtggacga ttatcctgaa atcattgaga aaataaagca agaattttat acgggcgagt
     5821 tcaaaaatcc tgcttgggag aatgagctag gctatccttt ggaggaattt atccaagaat
     5881 gttttgtaga atattcgagt gaaatcatga aggactatgt cgtacagatt acgaaagagg
     5941 tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca
     6001 cgattctttc atctgggatc attgactata tcgagatgag tggtgagatc aagtatggag
     6061 agaaagatcg cattgcgaaa atggtgaaag aatcaataaa aacctttgat gtgaaacaag
     6121 acctgacatt taatgattcc tatttgattg gaaagttgat caatattctt ggtacagatg
     6181 aagatacgga gctgtttctt tcttctttat caatgatatt tactgataag catttttcca
     6241 ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca
     6301 aactctatcg ggagaaaaca ccagatgaat tttatgattg gtttgagaag taaaataaga
     6361 aaagtggctt agattacaag ttggtgaaaa aatttttttc agcataacat cagtaatcta
     6421 taaaggggtt gttgattata ctgtagaagt taagtactca agagattttt tgtacgtaaa
     6481 caaagcaaaa aagggtgcag tttcactaga aaatgtactc ttttttgtga tttttcttag
     6541 ttatagagtt tttttgaaac tttaaaaatg agaaaacata ttgattttaa agagtgtaga
     6601 catagcttct tttgctaaat agattaaact tactggtgag tggtcttgaa catactttta
     6661 aatcacattt tactgagttt tattggattt tataattcat tggaaacctc gtacttaatc
     6721 tgtttttatc tatcgactag aatctgtata tattccagct atcaatgagg ccgcagaaaa
     6781 gggtgcttaa aaataatctg ttgtttaaaa tattattatc agaatactta gatacaaaat
     6841 tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg atatggtaat ctataaacga
     6901 aaatagtggt aacgtttcca aaatgcatct tcgttaaatt tttatttttt taaacgaaaa
     6961 tggaaacgtt tctaaaatgt attgggagga gattgaattg gaaaagacat tgggaccagg
     7021 tggtgagata agggcggtac aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa
     7081 gaaacagttg cggcgtgata agtggatgta cttgttgctc ttaccaggta tcatcatgac
     7141 gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt gcatttaaag actataatcc
     7201 tatgctagga attttggaaa gtccttgggt aggactagat cactttaggg aatttatcag
     7261 ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa attagtattt atggtttatt
     7321 gttaggtttt tttccaccaa ttattttagc actgagcttg aatcaaatta tcaataaaaa
     7381 aataaaacag aaaatccagt tgattctata tgcgccgaat tttatctcag tagttattat
     7441 tgtggggatg ctgtttttgt tcctatccgc aaatggacct attaatgggt tagtagaaaa
     7501 ggttacgggg caaccaatta tgttcatgtc taatccagct tatttcagaa cgatttatat
     7561 tttatcggga atttggcaag gaatcggctg gtcatccatt ctttacaccg caacgctggc
     7621 gggagtcagt accgatttat atgaggcagc aaatatcgat ggggcaaata ttttacaaaa
     7681 gatttggcat atcgatttgc ctgcattgag gcctgtgatg gtgatcagct tcatcttggc
     7741 cgccggcggt attatgaatg taggatatga aaaagcctac ttgatgcaaa cttcaatgaa
     7801 catccctgcc tcagaaatca tttccactta tgtatacaaa gtcggcttgc aatcaggtga
     7861 ttatgcctac tctgctgctg ttggtctgtt caatatgatt attaatgtcg ttttattact
     7921 gattgtcaac aatataacca agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa
     7981 aattatgaat agtgctttat caaaaatcga ccgtcaaatc ttatggttga atcgagtgat
     8041 tgtaactttt ttagtcgtca tcaccattgt tccgctgatt tatgtactgg tagcttcttt
     8101 tatggaccca gctactttga tcaataaagg tataagcttc aatccgaaag attggacaat
     8161 acagggatat caacgggtat ttgcagatga ttccatttta cgcggttttg taaattcgtt
     8221 gttttactct tttagcttca gcttattgac tgtatttatt acgatgatca ctgcgtatcc
     8281 tttgtctcga cctaacttgg cggggaaaaa gattattatg actttttttg tcattacaat
     8341 gttcgtgggt ggtggcttga tacctaccta tttattggta aagaacttgg gcatgttaga
     8401 tagtgtatgg gcgattatcg taccaggtgc tataaatgtg tggaatatta tcttagcccg
     8461 tacctatttt agtgctttgc caaaagaact ttctgaagct gctactatcg atggcgccaa
     8521 tgacttgcaa atactgttca aagtcatgct tccattagcg aaaccaatta tgttcgtatt
     8581 gtttttatat gcctttgttg ggcaatggaa ctcatacttt gatgccatga tttacatcaa
     8641 agatcccgac ttacagccgt tgcaactcgt attaagaaat attttgatcc aaaaccaacc
     8701 ttcacaagac atggtgggag ccaatactgc catggcagaa atgaaacaaa ttgctgagtt
     8761 gatcaaatac gcaacgatcg tcatttctag tctgccatta atcataatgt atcctttctt
     8821 ccaaaaatat tttgataaag gtgttttagt tggttctgtt aaagggtaag tattgttcac
     8881 tatttgtatg aataaaaatt ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc
     8941 aatcgttttt acttccgtac taattttggg ggcttgtgga ggctcaaaag aaaagagtaa
     9001 atcaagccct gattatgaac tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt
     9061 aaaaatgatg tctcaaagtg cccctttggc tcccaatgat cctaatgaca aattgatttt
     9121 ccaacgatta gaagaagaga ccaatctcca tattgattgg acaaactaca gtagtgattt
     9181 tgccgaaaaa agaaatttgg atatcgctag tggtgattta ccagatgcca tcttcaacgc
     9241 cgctgcaggt gactatgatt tattaaactg ggcggaaagt ggcgttattg taccgattga
     9301 agatttgatc gaagattata tgccaaatct gaagaaaatt tttgatgaaa accccgaata
     9361 ccgacaaatg tctactgcac ctgatggtca catttactct atgccttgga ttgaagaatt
     9421 aggcgaagga aaagagtcga ttcatacagt aaatgggatg gcttggatca acaaggagtg
     9481 gttggataat ttgggtcttg aaatgccgca aaccactgat cagttgatga ctgtgttgga
     9541 ggctttcaag acgcaagatc caaatggtaa tggtgaagca gatgaaattc cttttagctt
     9601 tattaacaat ggaggaaacg aagacttaaa atttttaatg ggggcattcg gtctaggtga
     9661 taatgatgac cacttagtcg ttgataacga tggtcaggta caatttactg ctaacaaaga
     9721 agggtataaa gaagccatca aatatttcaa tgaaatgaat aataaaggtc ttattgataa
     9781 agaggctttc gaacaagatt ggaatacgta tgttgccaaa gggaaagaac ataagtatgg
     9841 cgtgtacttt acttgggata aagcaaatat cacgggtgca gatgatagtt atgacgtctt
     9901 gccagtctta gcgggaccag atggaacgaa acatgttact cgtacgaatg gcatgggttt
     9961 ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac ttggaactta cagctaggtg
    10021 gatagataaa atgtatgaac cgttacagtc tgtccaaaat aactggggaa cctacggtga
    10081 tgaagcacag gcgaatattt ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga
    10141 ggggacagca ccgggggaac taagacaaaa aaccgaagct ggaggaccat tagcagttct
    10201 tgattcttat tacggcacag tcactactat gccagatgat gcgaagtggc gtttagattt
    10261 gatgcatgac acgtatttgc catatattac agaagacaat atctatccac gtgtcttttt
    10321 agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg gatatgtggg attacatcta
    10381 tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat gaagaatggg aagaatacct
    10441 tgctgaattg gaacgtgtag gtttggaaga atggattcaa ataaaacaaa ctggctatga
    10501 taattttttg aagggagcac aataagtgtt agtagaagaa acggcgattt tggataaagc
    10561 aaatcgattt attgaaatga tgcgaggaaa agttaaccct cagtatcgac aaaactatca
    10621 tttttccgca cccatcgggt ggataaatga ccccaatggg tttatatatt acaaagggca
    10681 ttaccatctc ttctatcaat actatcctta cgatagtcga tgggggccca tgcattgggg
    10741 gcatgcgcgc agtagtgatt tggtccattg ggaagatcta ccagtagcgt tagccccaga
    10801 tcaaccttat gacagcggcg ggtgtttctc aggaagtgca attgaaagag acggaaaact
    10861 atatttattt tatacaggct gtcaagaaat tgatggtatt agccatcagc atcaatgttt
    10921 ggcggtctct gaagatggta ttcattttag caaatacagt ggtaatcctg tggtagcaga
    10981 aaaacagcta ggtgaaaatg ggctaataca agaatttcgt gatcctaaag taattgttca
    11041 caacgatggt tactatatgg tagtagctac taaatctaca cagtctactg gtagaatagt
    11101 gatgtttcaa tcgtcagatt tgtatacttg gcacttttac tctgtgctgc tagaagggac
    11161 ttcagagcaa ggaataatgt gggaatgtcc tgatttattc catttagacg gacgagatgt
    11221 cttaatcatg tctccgatac aaatcaagaa gaacggactg gaatatcata atatcagttc
    11281 taccatggct tgtattggtg aggtaaactg ggaaacaggt cagatgatag ttgataattt
    11341 ccatgaaatg gattttggaa tggattttta tgcaccacaa acaacaagag atcctaatgg
    11401 tggacgggtg atgattgctt ggatgcagat gtgggatcgt acattgccta cacatgagtt
    11461 aggccatctt tgggcaggct ctatgagttt gccccgagag ttaagagtga aaaaaaatcg
    11521 attggtacaa aaacccatct caactgtata tagtcattta gtttatcaac aaggcagtga
    11581 aaatattgca gtgactgaca catcagtcgt atttcgaaac gcgctgtctg attcttcata
    11641 tttacatcta gtcgcagatt tggagaaagc tgaagttttt acaattgaat tactgcggtc
    11701 taagacggat tgtctcaaac tagcctatga cactgctaca caggtttttg aattggatcg
    11761 tcagaaacta ggaagagagc ttacaggggc ggaagaagac cctctgaatg tacgaaaagt
    11821 tgaagtacct ttgattgata atcagctcgt tcttgagatt tttagagata cctcatcaat
    11881 tgaagtcttt attaatgggt tagaagttat gacggctact ttctatgagc tggaaaaagc
    11941 tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt caagcttttg aaacagcgag
    12001 tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt atttaatagg ttttgaagga
    12061 taatgttttt agaaaagaac agatagctag atttcccatg gatttgctat tagtattttg
    12121 aaaaaattag taatttatga caaaattcat tatactaaac ttgtgcagaa atgtgaggga
    12181 tcaactatga aagcaacaat gaaagatgtc gcaaaattag caggtgttgg agtaggaact
    12241 gtttcccggg tattgaataa cggttctgtt aaagcttcta ctagagaaaa agttgaagca
    12301 gcaatgacag agttaaacta tcaaccagat ttttatgccc gggggttaaa gatgaagcat
    12361 acgaacacgg ttgctttgat tctacccacg gtatggcatc cattttttgg cgaatttgcc
    12421 taccatgtag aaacagcatt agaaagacaa aactacaagc tttatttgtg taactccagt
    12481 ggtaatagtg aaaaagaaca agaatatatc cagatggtca gccaaaataa agtagacggc
    12541 atcattggaa ttacttattc agatatcgat gaatacattt cgagtaatct gccttttgtt
    12601 agtattgacc gttatttcac tgaagaggtg atttatgtga ccgctgacaa tgcggccggt
    12661 ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc agaatgtagc atatatcggt
    12721 gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc
    12781 cgtcaactgg ggatttccta taaagcgtta gatatgttag aacctttaga ccatctctca
    12841 gaacgtgtaa caaatttttt gttagagaat cccgatatcg atgggatttt tacgatcaac
    12901 gatccaatgg cattagctgt cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag
    12961 gatgtccaag ttatcggatt tgatggtcaa aagatgacag aaggagatcc ttatctagtc
    13021 tcaacgattg cccaacctac aaagcaaatg gcggaagtgg cagtggcaaa attaattgct
    13081 gtcattaatg gagagacagt agaaaaacgt accgtattgc cgattgaatt tggcgaaggt
    13141 gacacaacga aacctttagt gagaaacgat tttgcttagt gcaaatacgt ttcttttttt
    13201 gaaaatgagt gaatgaaagg tgtagataaa atgttatatg gtggaataga agccggtgga
    13261 acaaagtttg tctgtgggat tggtaatgaa caattacaag tgatagaacg gaaaagtttt
    13321 cctaccacaa caccagaaga aacgatggag caagtgtttg atttctttga taagtacaaa
    13381 ggaaatatcg catcaattgg tgtaggagca tttgggccta ttgatattca aatcgaatca
    13441 agaacttacg gatatatcac caacacaccg aagttagctt ggcaaaatta tcattttgta
    13501 ggagctttgg aaaacgcctt gtcggttccc atctattgga ctaccgatgt aaatgctgct
    13561 tgttatggag aatatatggc agggtatgga aaaggtaaaa atagtgttct gtattacacc
    13621 gttggtacag gtgttggtgg tggtgctgta gtggatggga aaatagtcgc aggttttagt
    13681 catcctgaaa tgggacatat gctcttacaa cgtcataatg aagatcaatt tgaaggaatc
    13741 tgtccttttc atcatgattg tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc
    13801 tttggaagaa aagcccagac tatctcattt gatcatcctt attggacgat tgaggcagat
    13861 tatcttgctc agtgtgtgta taacacaacg ttactatatg caccggaagt aataatttta
    13921 ggcgggggtg taatgaaaca gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa
    13981 aaaatgggtt cctacgtgga tacgcctact ctcgaagaat atctactaac tccaaggctt
    14041 gctgacaatg cgggcttgat tggctgccta gctttagcaa taaagaaact caatcattag
    14101 aatagtattt attagaacta ttcataacat accggaagtt taaaagggta ttctgaaact
    14161 taaatagtct caattcattc ttctttcttg agaatctgag tagagacttt tattctgttt
    14221 caaattaata taattacgaa atgatattga gtacaagaaa gttcttttta ccagatcttt
    14281 taaatcgaaa aatctgatat atatatttat agtactaaaa atctgattag ataaaaagct
    14341 aattcaatag gaaaataaag gtagtgaata aaagcaaagc ccttgttagt agttaatcta
    14401 acaagggctt tggtagggaa aatggtagga aaccatctta ttttttacga aaatcaggaa
    14461 ctttagtaat tgaataatgt tgatttatag gtattcctca tccatattat gttggctctt
    14521 tattcccact ccactgttgc aggtggtttg ctggtaatat catacacgat acggttaacg
    14581 tgtgcgactt catttacgat acggacactg attttttgca agacttccca agggatacgg
    14641 gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac ggatacctac agtgtagtca
    14701 tacgtacggc catctcccat aaccccaaca gagcgaatgc ctggtaggac ggtgaagtat
    14761 tgccagatgt cgcgatctaa accggcattg gcgatttctt cgcgcaagat agcgtctgat
    14821 tcacggacga tttctaattt ttcttctgtc aattcaccaa ggacacgaat acctaagcct
    14881 ggtccaggga atggttggcg ccaaacgatg ctgtcaggca tgcctaattg ggtacctaat
    14941 tcacgtactt cgtctttgaa caatgtgttc aatggctcga tcagcttgaa ttgcatgtct
    15001 tcaggtaatc cacctacatt gtgatgtgat ttgatggttt gggcagtttc agttcctgat
    15061 tcgatcacat cggtataaag ggttccttgt gcaaggaaag aaacgccttc ttcaccggca
    15121 agtttggttg cttcatcatc gaagacatat acaaattcat ttccaatgat tttacgtttt
    15181 tcttctggat cagacacgcc agcaagtttt gataagaaac gttctttggc atcgactttt
    15241 ataatgttca agccaaattt tccgccaaga ctttccataa cttgttctgc ttcaccttta
    15301 cgcaacaata cgtgatcaac gaagatacat gttaattgat cgccgatcgc tttttgtaaa
    15361 agaacaccaa caacagagga atctactccg cctgaaaggc ctaataaaac ttttttgtca
    15421 ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga agttatccat tgtccagtca
    15481 ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca agtcatttcc atattcggaa
    15541 tggcgaactt ctgcatggaa ttggattccg tacattttgc gttctgcatt ttggatcgat
    15601 gcgatggggc aatctttgct ggtagcaacg acatcgaaat cagtcggtgc ttgggtaact
    15661 aggtcaccat gactcatcca aacggtttgt ttttcaggag tgttttggaa aagggccgct
    15721 tctgcagaag tgatttccaa ttctgctttt ccgtattcac ggtttttggc tggtttaact
    15781 tttccgccta atttataagt aatcaactgc ataccgtaac agattcctaa aactgggatc
    15841 cccaaatcaa aaatcttttc atcaatacca aaggccttct catcataaac actgtttggt
    15901 ccgccagaaa ggatgattcc tttagggttc attgccttta cttcttctgc ggtaatgcgg
    15961 tggctcatca actctgagaa aacaccgaac tcacgaatac ggcgagtgat cagttggtta
    16021 tactgactac cgtaatcaag tacgataatt tttggctctt cgtcaaatcg tgttggtgaa
    16081 gacaaatttg aataaaactt agtccgatat gcggcgcgtt ctgtgcgccg catatttttt
    16141 tagttttcaa agatcagacc ttgttgtaaa tagatccgtg cccgaaagtt ataaaagttg
    16201 cgataaccaa acgcaattcg tttaatcagc ttgatcttgt tattcagccc ctcagtgacg
    16261 ccgtttgagt gggacacctt aaaggcattt gaaatacccg attggtagcg atggaagatc
    16321 gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa ttgttttaag ggtttcttga
    16381 aagccttccg ta
//
LOCUS       DADVXK010000062        16149 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.063, whole genome shotgun sequence.
ACCESSION   DADVXK010000062 DADVXK010000000
VERSION     DADVXK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.063"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1244
                     /locus_tag="KB909_001863"
     CDS             <1..1244
                     /locus_tag="KB909_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6837883.1"
                     /translation="TDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSPSYCEHCRSVRI
                     IRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQA
                     ILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVLCMDEFKSMKSV
                     SGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLVMDMNASYCQLL
                     KTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLK
                     DSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGF
                     QETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFG
                     YRNFYNFRARIYLQQGLIFEN"
     gene            complement(1627..2355)
                     /locus_tag="KB909_001864"
     CDS             complement(1627..2355)
                     /locus_tag="KB909_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBB6837884.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(2333..3907)
                     /locus_tag="KB909_001865"
     CDS             complement(2333..3907)
                     /locus_tag="KB909_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6837885.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            4136..5074
                     /locus_tag="KB909_001866"
     CDS             4136..5074
                     /locus_tag="KB909_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6837886.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            5086..5997
                     /locus_tag="KB909_001867"
     CDS             5086..5997
                     /locus_tag="KB909_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837887.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            6021..7493
                     /locus_tag="KB909_001868"
     CDS             6021..7493
                     /locus_tag="KB909_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6837888.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            7544..8155
                     /locus_tag="KB909_001869"
     CDS             7544..8155
                     /locus_tag="KB909_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6837889.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            8185..10098
                     /locus_tag="KB909_001870"
     CDS             8185..10098
                     /locus_tag="KB909_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBB6837890.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            10226..13207
                     /locus_tag="KB909_001871"
     CDS             10226..13207
                     /locus_tag="KB909_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBB6837891.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            13204..14865
                     /locus_tag="KB909_001872"
     CDS             13204..14865
                     /locus_tag="KB909_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBB6837892.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            14905..15837
                     /locus_tag="KB909_001873"
     CDS             14905..15837
                     /locus_tag="KB909_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6837893.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         5237 a         2611 c         3234 g         5067 t
ORIGIN      
        1 taacagataa acatttattt tttgatgaag aatggctgat tgaaaaagaa tataaaggcg
       61 ttcaagcgca gtttattaaa ggaaaattgg atgactctcc ttcctattgt gaacactgtc
      121 gatcggttcg tattatccgc aacggttcct atacgacacg cactcagata ttgaaagtca
      181 aagaaaagtt aactatttta gaattaaaac gtacccgttt tctctgccat gattgtggaa
      241 ggaccttttc tgcgaaaacg gacttagttg atgaacatca tcaactaaca aaggaactga
      301 agcaggcaat tctcatggaa ctgtacgaaa atcaatcacg taaactaatc gctaagaagt
      361 acttcgtctc ggatgggacg gtgacacgga tcttgcgtga agcaacgaag cattaccagt
      421 cacgtatgaa cttccttccg acggtgttgt gtatggatga gttcaaatca atgaagtctg
      481 tttctggttc catgagtttt atttgtgttg atgggacaac ccatcagcta tttacgatcc
      541 ttgaagatcg cagactttac aaactaactc aatacttcct gcactttcct agaaaagccc
      601 gtttaaaggt caagtaccta gtgatggaca tgaatgccag ctattgtcag ttgcttaaaa
      661 cagtctttcc aaatgcggag atcgtaactg accgctttca tattgtccaa cacatcaatc
      721 gcagcttcaa tcaattacgt gtccagatca tgaatcgttt tcgaacctca cactctgaaa
      781 atcagaagaa gtaccgtcgg ctcaagcgat attggaaact cttactcaaa gattccacga
      841 catgggagcc actcaaacgg cattatcatc gactgtttaa acgaccaatt agtcaaacag
      901 aaatcgttga tgagctgtta agctacaacg aagaattgcg aactgcgtat catttttgtc
      961 aattattacg ctattatttc gttaaacgag gtacggaagg ctttcaagaa acccttaaaa
     1021 caatttcatc tacgttacct cagtcgttta aaaagaaatt cacgatcttc cattgctacc
     1081 aatcgggtat ttcaaatgcc tttaaggtgt cccactcaaa cggcgtcact gaggggctga
     1141 ataacaagat caagctgatt aaacgaattg cgtttggtta tcgcaacttt tataactttc
     1201 gggcacggat ctatttacaa caaggtctga tctttgaaaa ctaaaaaaat atgcggcgca
     1261 cagaacgcgc cgcatatcgg actaagtttt attcaaattt gtcttcacca acacgatttg
     1321 acgaagagcc tatttaaata actacatcca tttattctat cttctaaaat agcctttttc
     1381 atttcagtta aatagttcag cgccattttt gcactcgact tgcatagtag ttttttccat
     1441 attcctcaac ctcagcgggg gttgaagaca taaggaaaat cctatgcgtt atgctcaact
     1501 ggatctgatt aaatattcta atgtattttt ctctaccatc attaaatggt taatagccaa
     1561 aaatcaccac ttttcaatgg ctccttgttg tataagtata actagaagat gaacacgtct
     1621 gagaaattat agaagctttt tacggtaatt actggggctg tgtccagtag tttttttgaa
     1681 gagaacagaa aaatagctca cgtgatctat tcctactttt tgactaattt catcaataga
     1741 taagaatgtg tctttcagta gagcacttgc tcttttgatt cgaaagtcta gcaagtaatc
     1801 atgaaaggaa taacctgttt cttttttgaa ggcccgtcct aaataagcgg gatggtaatg
     1861 gaattgtgta gctacatctt tgagcgtaag cttttcacta taattgtttt gaacgtaatc
     1921 aatcacttgt tgaattgact cattaaaaga atcatcagtt agagagtttt gattagctgc
     1981 tgatttacgc attttttctt cttgtactaa cttaactaaa taaggaaaat caatgggttt
     2041 cgttatgtaa cttttaatag ataaatcaat cccctttttt gcatactgaa aattttggtg
     2101 ggcactaatg acaatactag taaagtagcg attggatgtt tgttgcaaag attcgattaa
     2161 ttcgagtcca gaaattttcc ccatcgtaat atctgtgata agtaaatcaa agcgctggtt
     2221 ttgcaggttt ttaaatgctt cgtctccgtc tgtgtagcag tgatcgataa tgatgtcggg
     2281 gactttcttc aaaagataat gccttatgcc ttctacaatt gtacaatcat cgtcaacaat
     2341 tgcaattctc aacatgcata ttcccccctt tttgtatttt gatagtaatc gttgttccga
     2401 cgtgtagttg gctttctata acaaaacgtg tatctccagg atagagatgc tttatacgtc
     2461 gaaaagaatt tgagatgccg atattctcac tataaggaat atcatcatta agtttttgtt
     2521 gaatatgctc cagcttgtct tggtccattc ctttcccatt ttcaacgatt tttaacacat
     2581 aatggttggt tgtttcagtt gcatagacag tcaaacgatt ttcctttttt gatgaatcga
     2641 agccgtgttt aatataattt tcaacaaatg gctgtaaaga aagttttggt aacattaatt
     2701 gatcaatatg atcaatcagc tgatagtcaa agttatgtcg ataacgacgt tgatgtagtt
     2761 gcaaggagag gtcgatatta attaattcct ctttcaaatc aattatgtcg ggctgatatg
     2821 tattattgcg atacaacttg ctcaataaat atatactgtc gctgatttct tcgtcatcat
     2881 tcaatatggc agtcattcga ataaattcca aattattaaa tagaaaatga ggctcgattt
     2941 gatattgaag tgctgcatac tttgcttctt gcttcaacca attattttca taaagtgttt
     3001 tttgatatgt agcattatct aaataaaact gattgatatg catagcgatt tctttcaaat
     3061 caccgacttt gttttcgata ttgattgact tgtagtctcc tgtagatgaa tgatttaagg
     3121 aagtaatgat ttcctgatac tgctggatat agttacgaaa acttctattt aataattgat
     3181 gaatagcaag aataaacaaa ctcattaata agaaaatcat gattgccaga cctaataagg
     3241 tttgtgacga ataatttgga ttttcatata cttgtaatgt gtggttaccg atagctatct
     3301 gttgcgtttt tttccattta gaaggcgaga tgtcttcaga taaattgacg gaatcaatac
     3361 cattagacaa agaataattg taatgtgttg gaaagagact cttttttagc gcgttgatcg
     3421 aaacgtctag aatcaatgta gcatcgggca tgtcctcact aatgaaactt aatgaacgaa
     3481 taaaagaaat tttttcgttt tttgtaggtg cgtaggcact taagtatttt tcgtaatcta
     3541 atgagataga tatattttta acttcatcat cttgcacaag tttttttaag ttatctacta
     3601 aataggtagg ggagcgatcc tttgacaaaa tatcttccat gtattcagca ggtgatgaga
     3661 ggtagtagtc attaaggttt tcttggaaat cataattttg atagatctct gtcacgatac
     3721 cggagagaat acgattatat gtttccatat agtgggtgat ttgctgaatg ttttgcaggt
     3781 tttgattttt ttctttttca atcacattga tataggaaaa gaacaatgtg aaacaggcaa
     3841 gtaaagtaat aaaaaaaatc aatatgtatg taaaacgcat aataactttt gataaatcgt
     3901 ttttcattca aagtcctcat tttgataatc tctaatttta tgaatcatta tagcacatat
     3961 tacaagtgat gtaaacgctt tgcaaacagg gctacttatg attgtgaata cagtttccgt
     4021 ttaaaaacta ttctattgta gaggtttaat aaactaaaaa taatgtataa aaaattaatg
     4081 taagcgatta accaagtggg tataatcaag gaaacgctga gagaggagag acaaaatgaa
     4141 gctaaagaaa gggttattag gaaatctaaa aaaaaaccga gcattgttta ttatgctttt
     4201 accaggtgcg ttatggttat ttatattttg ctatatacca atgtttggag ttgtaatcgc
     4261 ttttaaagat ttcagaattt catcaagggg attctttaca agtttgttca acagtccttg
     4321 ggttggctgg gaaaatttca aatatctctt tgcttcgcaa gatgcttgga tcattactcg
     4381 caatacggtt gtttataacg ttgtaggtat tttgctaagt actttttgta cagtgtcatt
     4441 agcaatcatt ctgagccaaa tggcgaacaa acggttattg aaaaagatgc agacatttat
     4501 gatttttcct aattttttat catgggtagt catcagttac tttgtttacg catttttgag
     4561 tacggataaa ggattaatta atattttact aagcaatttt ggtgtggaac ccataaattg
     4621 gtatagtgaa ccgaagtact ggccttttat tattgttttt acgagtttat ggaaaggcgt
     4681 aggctatgga tccatcattt attacgcgtc aattatgggg atcgatacta gttattatga
     4741 agctgcttta gttgatggtg ccagtaaatg gcaacagata aggaatgtag tcttgccaca
     4801 tttaagatcg attattgtca ttatgttgat tttgtctgtt ggtagtattt ttcgagctga
     4861 ttttggattg ttttatcaat tgccaagaaa ttcgggggct ctttatgatg tgacgaatgt
     4921 attagatact tatgtctacc gtggattaat gaatagcgga gatatcggaa tgtctacggc
     4981 agcgggatta tatcagtcat cagttggctt tgtcttgatt ttgattacta ataagatagt
     5041 caacaagtta gatcctagtt cagcactatt ttaggaggaa tcaaaatgat atcaaaatta
     5101 aaacggcaga tgtacttttc gctgccagtc gaacggtttt tcacaatatt actaatctta
     5161 tttactctta gctgtatttt tccctttatt ttcgtaatcg tcatttcatt aacagatgaa
     5221 aaagcattac aactcaacgg ttacgaatta ttgccggctc aatggagcac tgatgcatat
     5281 caatacttaa tacaagatgg cggacagtta cttcggtcat taggcgttac aattatgatt
     5341 acagtgattg gaacgttgat tactgttttt atgacgggaa cctatgctta tgttttatca
     5401 agagcctctt tcccttaccg gaagttcttt actttttatc ttttttttac catgttattt
     5461 gcgggaggga tggttccttc ttacttagtg atgacgaaga tgcttggctt aaaaaataca
     5521 atttgggctt tgattctacc tcttgctttt agcccataca atgtcattat tttaaggaca
     5581 ttctttaaga agtcgattcc agaatcgatt atcgaatccg ctaaaatgga tggctgtagt
     5641 gagtttcgag tttttttcca aatcgttttg cctttagcga tcccaggggt tgcaacaata
     5701 ggtttatttt caagcttagg ttattggaat gactggttca acgcattgct gtatattgac
     5761 accaacaaat tgattccatt gcaatatttg ttaatgaaga ttcaaaattc aatggaattc
     5821 ttagcaaata ataatgacat tacattagcg cagcaacaag caattcaaaa tagccttcct
     5881 caagaatcaa cacgaatggc aatggtcgta gtagctactt taccgattgc aattgtttat
     5941 ccgttcttcc aaaaatactt tgttcaagga ttgacgatcg gtggagtgaa agaataaaaa
     6001 agaataggag atgttaaaag atgaaaaaga acatgcagaa atatttgatt ggtggtgctt
     6061 ctgtactaac ccttggccta ttaggtgctt gtggtagcag taatggcgaa gcaaataatg
     6121 aaacaggaac cacaaaagtt acttggtatc aggttggaga agaacccaaa gattttgatg
     6181 aggtcatgac aaaagtcaac gaaaaattaa aggaagaaat caatgtagag ttggatatgc
     6241 ggctgattcc ggacggggat tatcagcaaa agcttggtgt gatgatcaat tcaggagaag
     6301 aatatgatat ttgtttcgtc aatggcacag attatgtgaa ttatgggaac aaaggtgctt
     6361 tcattagtct caacgatcat ttggataaag agttgaaaga ttatgcagct gaattgaatg
     6421 aaggatttat tgaaggtggg gcaattaatg gcgaaactta tggattgcca gtcaataacg
     6481 atattgccac aacggaatat tggaccttta ataaagattt ggtagatcaa taccaattgg
     6541 atgtagagaa tgttgaaggt gtagaaacat tggctccagt attagaaaag tttgcagaaa
     6601 aaaatactga tacgaatatt acgccaatcg gtatgacccg taccagtgtc tgtattcctt
     6661 atgacaatat tatcggtggt ggtgtaccgc tagcggttgc atttgaaggc gatacacaaa
     6721 cagttgttaa tacttatgag actccagaaa tgatgactta tttgaaggct atgcatgagt
     6781 tttataaaaa aggatatatt ttgaaagatg cagccactgt tacgacagat ccatttcgaa
     6841 ttgatagtaa aaactggttt ttaggtcgta actcaagtgg ttatcaacca ttagcacaaa
     6901 aaaaattaga agctctagcg ggacatggat taattttaaa accagctgga aaagctttta
     6961 aaacgactgg atttgcaaga gtggcaatgc atgcggtatc tgcttcaagt aaacatccgg
     7021 aagcagcctt gaaattgttg aattatgtga ataccaatca agaagtagcg gatttaatgg
     7081 tttatggaat tgaaggaaaa cactatgatc gcaatgaaga tggttcgatt actttaacaa
     7141 actctgatga ttattatcaa ggcgcttggg cattggtaaa tacttatcta gtttcaaaaa
     7201 cttcaccgat tacagaagaa agtaaaaaac tagaagaaga aagtaaaaag tttcaaaatg
     7261 aagcaccgat gtctcctatt ttaggtttct cttttgacgc ttctgatttt cgaacagaaa
     7321 ttgcaagtgt acaaaatatc gtgtcacaat atgaagtact tttaagctcg ggaacagttg
     7381 accctgaaca atatgtacca gagttgttag aaaaactaga aaaagctgga ttggataaaa
     7441 ttcaggcatc tgctcaagaa caatacgatg aatggcgaaa atctaacaaa taatttttta
     7501 ctaaatgaaa agaatagact aagcagttag tggggggatt caaatgaacg aaaacaaatg
     7561 gaccaaagga tttaattggg tttttcaatt gttgttacta aactttactt attttatact
     7621 aatttgttta ggatttggaa ttttaggttt tttccctgct acgatagctt tgattgctgg
     7681 cgttgtgaat cgaaaaaaat atggcttgca agagtctgtg aagttcatga gtaaaatcta
     7741 taagaaaaat tttgttagat ataatctata ttgctggtca gcaactttgt tgttggccgg
     7801 caatattact acgatctggc tttgttggca gcaaagcgca ccattgtttt atttattaag
     7861 tacattatta tcggtaatta cactgttcct agtctttgca atgttgaatt gggtcgtgat
     7921 caaaagtctt gggttgtgga tgatgggaga ccgactgatt gactatttgc ttttcacagc
     7981 aacgatgttg ccaacggtag tcatgcaagg cttggtgctt ggaatttatt tccgaatatt
     8041 gatgattttg cctgtgattt ttctgtttgg cggaacagct gtaacggtaa tattgattag
     8101 taaattaact gaaagagcgt tagcaaagtt gccttgtcag atacaatcgc actaattttt
     8161 tcacaaaaag gagtatttct ttctatgaag ttaactgata aacaagtagc taatatagcc
     8221 tttatccagc aacttgagat tccattgaca caaaaagatg aagaacaaat agacttgatt
     8281 tttactgaca caaaggctaa tgtgcgacaa atcaagatta ctaaaaatga gcagcaacga
     8341 atttgcttgt cttattcaca tgaagacttg ctgtatcgag gattgtttat ctgccttcca
     8401 cgttttttag ctcaaggagg agagatgcca tacattgaag aaacctcgat cattgagacc
     8461 agttattcat tagatgcttc tcgtaatggc gtgatgaata aagagactct aaaaaaattc
     8521 atttcttact tagcgttgat ggggtacaac acattgtata tttacacaga agatacctat
     8581 gaagtagaag accttccata ttttggttac cttcgcggag cgtatacaaa agaagaagtg
     8641 aatgaaattg ttgaatttgc ttctggtttt ggcatagaag tagttccatc gatccagacc
     8701 cttgctcact tgacccaatt tttgaagtgg tatgctcaac aagaactgat ggatgatcaa
     8761 aatactctac tgatcggtga agaaaaggtt tatgcggcaa tcgaaaagat gattattgcc
     8821 tgcaaagaaa tgtatcagac agagcgtatt catttgggaa tggatgaagc ctatcaagca
     8881 ggtctgggac gatatttaag cctgtatggg tattgtgatc ggacaacttt aatgattcaa
     8941 catatggacc gtgtgttatc aattgttgat aaatataaga tgaaaccaat gatttggagt
     9001 gatttcattt ataagctatt agatgaaacc ggtaaagata ggtattacaa tcctgatttt
     9061 aaactcaaag cattagcagc taaaggatta ccagcaggat taacctatgt tcattgggac
     9121 tatggttcag atgaagtttc ctcctatgag aaagtaattg ataaccattt gaaattttgt
     9181 gacattgatc attacgtttt agctagtggt gcccatatct gggggagact agccccgaat
     9241 catgggaaaa cagaagcaat tgtttctgca gctgtaaaag cttctaaaaa taaaggtgta
     9301 cgttctgtga tgttaactac ttggggagat gaagggcagg aaacagagca ttggcattcc
     9361 ttaattgggg cattaaaatt agcagattat gtctattctg aagaagagtg gaatgatttt
     9421 gaggaaatct acgatcgttt attaggaaca ggtagttatc aattaatgtc cgaattacga
     9481 tatttcgatg aagtggatac cattacaaat aacaacttac aaatggcttc cgtgagtaaa
     9541 ctgctacttt ggcaagatcc gttagttggt atatatgact ttcatgtagc cgctcataac
     9601 aaaattgcca ctagaacaat tggtacttat tatcatgagt tagctcagaa attagatatg
     9661 aataaaaatt ggaatccaaa acaaccaatt ttaacaacta ttcgtcaacg atatatactt
     9721 ttagctgaaa ttttagcaca aaaggcagaa ctaggcatct atttacaaca ctgctgtctg
     9781 gtagaagacc ttgcaggatt aatggaatta gcgaatcggt gtgaagcact agccaatcga
     9841 gtaaatgaat tggcatctat tcatgaaata atttggtatc aaacatacaa aacctatggt
     9901 tgggaagtat tagaacaacg atatgctgca ttagctcatc gtctgaaaac cgttgcgcgt
     9961 cgtattaaaa atcatcttca ggggcaagat gccctagagg agcttttgga agaacgatta
    10021 ccgttttgtc aatatcaagt gccgcttgaa atttctggct ttaattatcg gcaaagctcg
    10081 gtgtcaggct acaattaacg aaggaatctt cccgttgaac ggaccacttg ctcatctaat
    10141 gggaaagtgg ttcgttttct attcataagt agcttaccac taactctttt attaagaaga
    10201 gaaaaaaagt aggaagtgag aaaatatgtt atcggactat tatcaaaatc tgtcagttat
    10261 aagtgtcaat acagaaccat tacgtaatta ttatattcct tatgcaagta aagaagaagc
    10321 aaaacaagag ttagaaaggg aaaaaacgag ccagtttatc gatctcaatg gtacatggga
    10381 ttttcagtat tatccttctg tccaacagtt accggaaaat ttttttcaag aggcctttac
    10441 tgaaagctat gatagaattt ctgttcctgg agtttggcaa acagagggat ttgacttacc
    10501 tcagtatatc aatgtatctt atccaattcc ttttgatccg ccttatgtac ctaatgatac
    10561 cccttgtggt gtatatcggc gtcagtttca aattgagcaa acagatgcac gcttttactt
    10621 aaatctagaa ggagcagata gtaattgttt tgtttggata aatagaaact ttgtaggcta
    10681 tgaccaagtg agtcatagta catctgaatt tgatgtgacc aagtatttac aggttggggt
    10741 taatgaaatt caaattctag tgatgaagtg gtgtgatggt acctactttg aagatcagga
    10801 taagtggcga atgagcggtc tatttcgtcc agtgtatctt cttcaacgac caactatgca
    10861 tctgacaagt tatcaactac ggacgttgac tgatcctaaa aaaggaagcg gaacattaat
    10921 ggtttctttt caacgattta ctcctattga agtatcgtta cctatttctt acgaattatt
    10981 ccatcctgat ggacgtctca tagcgaaagg ggagtgttac tcggaacaac aaataaattt
    11041 ggatgttgaa gattgccttt tttggacagc agaaacgcct aaattatata cattactttt
    11101 aacatgtaat ggtgaatatt ttaaagaaaa agttggcttt cgagcactga cgatcaagaa
    11161 tcgtaagtta ttgctgaacg gaacacctat taaattatat ggagtcaact atcatgacgt
    11221 gaatcagcaa ggcacgccag tgatgacccg agagcagtta cgtgcagatt tgttattaat
    11281 gaaaaaatta aatgtgaata ctgtacgaac ggcacattac cctaaatcac cagattttta
    11341 tgaattggcg gatgagattg gtctgtatgt aatcaatgaa gcagatttgg agtgtcatgg
    11401 tgtggttaat ctatatgata ctgaagcgaa ttatcaacta attgctaatg atccgacatt
    11461 cgaaaagccg attatggacc gagtgatccg ttctattctt ccttatcaaa atcgaagctc
    11521 tatcattatg tggtctatgg ggaatgaatc tggttatgga gtaaattttg aaaaagctca
    11581 agctttagca cggaaattgg atgattcacg gttgattcat aatgaacgct cgattgaacc
    11641 agttattgac caagtgaatg attttagtaa cttggatgtt attagtcaaa tgtatccccc
    11701 actggaagat gttcatcgtc attgtcaaag aagtgatact gaaaaacctt tttttatgtg
    11761 tgaatatagc cacgctatgg gcaacggtcc tggagatctt aaaacgtact tcgatttgat
    11821 tcaacagtat gattcctttc ttggcggttg tgtctgggag tggactgatc atgcaatcaa
    11881 tagaggaact ttagaaacgc catcttattt atacggtggt gattttggtg aaaaatatca
    11941 cgacggcaat ttttgcgtag atggtttatt gaccccagat cggcaattaa cagtaggtgc
    12001 attggagtac cgtaatattc attcgcctat tcaactgatt gctgtagatg aggagctgca
    12061 agaagtaacc ttgagcaata taactgcttt tacagccggt tcagcattta acctttctct
    12121 tgaatggtat atagatggaa aaaaaacagt ttatgaagta atgaatcctt tcatacttga
    12181 gcctggcaaa agttgttcat tgcccatcac agtacctaca acgattcatg gtgctcatac
    12241 ggttgctgtt tcgctatctg tttataaaaa tgatgagctt tatggacagc aacagctctt
    12301 tcttaaaaaa gaaaaaatga gattgccaag aactgctcat cataatgatg caccacaaat
    12361 ttcagtaaaa ggcacagagc tgataatcaa aggagaatcc tttatttata tatatcaatt
    12421 agcaaaagct gcgttcactt ctgtaaagat caatcaaaag gaacttttgg aacgtcctac
    12481 tcaattttca atttggcgtg caccaacgga taatgatcgt aacttagtaa acaaatggaa
    12541 agcagctgga tatgctgaaa tgtctttaga aatcagaaaa aaagactgga aattcgtaga
    12601 tgatcatctc ctgatcgaaa cgtcttatcg aggagttatt ccaggattac agccaatttt
    12661 tacaatgcac atacagttga aaataaatgg tgcaggcgta atcaaccaaa aagtatcagt
    12721 ggagaaaaat ccgatttttc cagatttccc tcgctttggg atggactggc cgttgaatga
    12781 tactttttcg aaggtttctt attgtggcta tgggccgtat gaaagttatc ctgataagca
    12841 ctatgctgcg atgtttggta tttatgagat ggagattgag gaatttgatc agccatatat
    12901 caaaccacaa gaatatggta accgctggca atgtgattgg gtatcaatca aaaatcatca
    12961 aggatctacc atgacggttt atggaaactc taatttttct gctctgcctt atagtcaagc
    13021 tcaattaacc gaaaagtcac accattatga attaataaaa gaaaatagaa cttggttcaa
    13081 tttaagttat aaacaaaatg gtatcggctc acacagttgc ggtccttatt tagaagatcg
    13141 tttccgtttt atggaagata cttttgactg gaatatagtg attactttca aaggagaaaa
    13201 tagatgaaag aaacaaagat caatcaagtc aaaaaaaaat tatctcgtta tcaagaagtt
    13261 gtttatcgaa accattgctt aaaatggtca aaaaataagc tgaatgttcg ttttaatgga
    13321 ttattttatc gtttcgaaca gttagaagaa gtctggaaac cggtaacgaa tttccaatca
    13381 tgtcctgtac agctcataaa tgatccaaaa gaaacatacg atttatgtat aacacacctt
    13441 tataaccagc atttgaaaaa tgacggattt tatttaaagg ttactaatga caatcaactt
    13501 acgattgaat cagcaaacct tcgagggttt caatatgcta tggaagcctt attagagagt
    13561 tttttttcgg taggagatca attattatta ccggaattga ttctgaaaca tgaaccatca
    13621 gtgaaaattc gaggaatcat tgaagggttt tatggtatcc cctggacaca tgaaatgcgc
    13681 ctctctcttt tttcatatat gaaagataac caattgaata cttttatgta tgcccctaaa
    13741 gatgatgaat tattacgtaa aaaatggcgt gaactctacg atgcgcaaga attagacaaa
    13801 tttaaggagc ttttatctgc tgctgaggct agcaatatcg atttttggta cttaattagt
    13861 cctggaaatg atattgatat tacgtgtgaa gaagacattc aagttcttct gaaaaagtta
    13921 gaacaactga ttgagcttgg cgtatttcaa tttggtctat taatggatga tattgactat
    13981 caattaaaag gtgctgctaa acgccgtttt cgagagccag cattcgctca tgcctattta
    14041 gtgaatcgag tagaggaata tcttagcact cggttgtcca atcatgaatt agtcatttgt
    14101 cctacagaat atgataatcg tcatggttct cgctatttag caacgttaag tcaagaaata
    14161 ccagaacaat taccgttctt ttggactggc ccaagcacgt tagcggcgtc aatttctaca
    14221 gaagagctgc aggaaatggc ttctgtctat caacggccga tgctgatttg ggataatatt
    14281 ccggtaaatg attatttaga ggataaagaa ctattgttca tgagtccata tgagaatcga
    14341 acaccgaatc tttctaagga gagataccag gttacaggag tagtttcgaa tccaatggct
    14401 caattagaag cttcaaagtt tacgatcaat agtatggcta attacttatg gaactgtgag
    14461 cgttttgatc ctttggaaac ttggacgtca gtcgttgaaa aagtagttgg aagtaaacta
    14521 caaccagctt atcttacctt aaccaatgct tttccaaatc attacacaag cagtctgctt
    14581 tcagatgaag aattactgct agccaaagac ccagaatggg tcacaaaaga aatggctgct
    14641 ttagtccaag cagtaaaatg gatccagcaa gaacaacata catctagatt gagaacagaa
    14701 ttggagcctt ggttacaagc aatcacagaa agttggactt tctggcaaga atggcaatta
    14761 aaaaaagatc caaaagaagc agaagaatgg ttggctaaga aaaaaacaca ccgcatagga
    14821 cgtgatttag taactgccca tttagagcaa attatcaaaa gttagatatc ttaaaaaata
    14881 aaaagcaaga aaaaggagaa caaaatggtc aagagattaa ttagtgcaaa ctacagtgat
    14941 gtcaagaaaa tgacgtcaaa agagttgaag caatccatca aagcgagtga aggacgggtg
    15001 attgtttgtg aaacggttgc taatactctt ccacaatctg gagaaattac gaatgcagaa
    15061 gttgcgtcag catttggtgc agatttgatt cttttaaatg gtttcgattg ttatcgtcct
    15121 gcagtttttg gactaccaaa tgtgacgatt gagaaggttt ttgatctaca gcaaacgatt
    15181 gaaaacccga ttcctaaatt aaaagaacta gtcggtcgtc ctgtgggaat taatttagaa
    15241 cccattgccc ctaaaacaaa tatgatgagt gagaaagtag aaatcagcca aggaagagca
    15301 agctctgttg aaacgataca aaaagcagaa gaactaggag tcgattttat ttgctttacc
    15361 ggtaatccag gcactggagt aaccaattta gaaattacta aatccgtaaa aatggcaaaa
    15421 aagtattttt cgggattgat tattgctggg aaaatgcata gcgccggctc agaagagcca
    15481 gttgtgaata aagaggcgat tatttcttat gcggaagcag gcgcagatat tttactagtt
    15541 ccttcagtag ggtctatccc aggcttttta gagcaagacc taattgaagc ggttcggttg
    15601 gcaaaaaaat atgatttgtt aacgatgtct gcaatcggta ctagtcagga aagtgcccga
    15661 ccagaaacat tgcggcaatt agccattatg aataaaagtt gtggtgttga tttacaacat
    15721 attggagatg ctggatacgg gggattggca ccagcagaaa atattttcga aacctcggtt
    15781 gcaattagag gaatgcgaca taccatcaac tgcgttagcc gctcgatcaa tcgctaacaa
    15841 aattaaataa aaaatggtta aattgattat ttaagtggga acatacttga gatatcagct
    15901 aacttctgtc actttaaaaa agggactgtg acagaagtga aaatagacaa aaaatatccg
    15961 aacaagagac taggatagca gaaaaactat cgttttgcaa cgaggaccaa ctggaccgta
    16021 ggagcaattc tcttattgtt cggatatttc gcttgttcaa ggacttatgt ctgtagtgcc
    16081 cttttttggt aggaaaaatg gtagggaacc atatcatttt taatgaaaat caagcatttc
    16141 aaaagttga
//
LOCUS       DADVXK010000063        15893 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.064, whole genome shotgun sequence.
ACCESSION   DADVXK010000063 DADVXK010000000
VERSION     DADVXK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.064"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            183..1610
                     /locus_tag="KB909_001874"
     CDS             183..1610
                     /locus_tag="KB909_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6837894.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1702..2067)
                     /locus_tag="KB909_001875"
     CDS             complement(1702..2067)
                     /locus_tag="KB909_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBB6837895.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2064..2429)
                     /locus_tag="KB909_001876"
     CDS             complement(2064..2429)
                     /locus_tag="KB909_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBB6837896.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2621..2869)
                     /locus_tag="KB909_001877"
     CDS             complement(2621..2869)
                     /locus_tag="KB909_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837897.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2868..2996
                     /locus_tag="KB909_001878"
     CDS             2868..2996
                     /locus_tag="KB909_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBB6837898.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            3053..4747
                     /locus_tag="KB909_001879"
     CDS             3053..4747
                     /locus_tag="KB909_001879"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBB6837899.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4751..4870
                     /locus_tag="KB909_001880"
                     /pseudo
     CDS             4751..4870
                     /locus_tag="KB909_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4847..5020
                     /locus_tag="KB909_001881"
     CDS             4847..5020
                     /locus_tag="KB909_001881"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837900.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5398..6531
                     /locus_tag="KB909_001882"
     CDS             5398..6531
                     /locus_tag="KB909_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBB6837901.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6562..6882
                     /locus_tag="KB909_001883"
     CDS             6562..6882
                     /locus_tag="KB909_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBB6837902.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6911..7375)
                     /locus_tag="KB909_001884"
     CDS             complement(6911..7375)
                     /locus_tag="KB909_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837903.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7507..8760)
                     /locus_tag="KB909_001885"
     CDS             complement(7507..8760)
                     /locus_tag="KB909_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837904.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8789..9106)
                     /locus_tag="KB909_001886"
     CDS             complement(8789..9106)
                     /locus_tag="KB909_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6837905.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9132..9452)
                     /locus_tag="KB909_001887"
     CDS             complement(9132..9452)
                     /locus_tag="KB909_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837906.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9916..11331)
                     /locus_tag="KB909_001888"
     CDS             complement(9916..11331)
                     /locus_tag="KB909_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6837907.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11348..12664)
                     /locus_tag="KB909_001889"
     CDS             complement(11348..12664)
                     /locus_tag="KB909_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837908.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12814..13512)
                     /locus_tag="KB909_001890"
     CDS             complement(12814..13512)
                     /locus_tag="KB909_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBB6837909.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13801..14757)
                     /locus_tag="KB909_001891"
     CDS             complement(13801..14757)
                     /locus_tag="KB909_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6837910.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14870..15703)
                     /gene="msrA"
                     /locus_tag="KB909_001892"
     CDS             complement(14870..15703)
                     /gene="msrA"
                     /locus_tag="KB909_001892"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6837911.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
BASE COUNT         4953 a         3207 c         2706 g         5027 t
ORIGIN      
        1 attgttaaaa attcgcaatt tattttttaa tagaattatc tgttttccaa attttataac
       61 ataaaaaacc ttttttaacg gcatttatat gctttttcag aaattaactg atgatttcaa
      121 aaagaaaaca tgtcataata tttcccatat tgtgcaaaaa aatacaaggc ggaggctcta
      181 ctatgattga agaatatatt gagaaaaata ttttaagaca gctgttttta tgtgggcaat
      241 tctatgtaaa taaagaagtc aatctagaaa agctctccaa tctcctgcat gtttgcaaaa
      301 ccactttact caatgatatc aataacataa aaaaagaatt tgaagaacag atcgcttata
      361 cacatcggga aaaggaccgt tacactttat atttttcaga acatatacct cgatgcaaga
      421 tcatgcagca attgtctcaa aattcgttgt ttttaaaaac ttgtctgctt tatttggaag
      481 aagatgaacc tgattatctt caattaactg aatgtgaatt catctctgtc agcaaagctt
      541 attcattaaa aaaacaagta ttagcttatt ttaatgactg cgggatcgaa atcgaccgct
      601 actcccctcg attcactgaa atggaaagac gtctgctgct tcttaatgtg tcgtatcgtt
      661 taggcggttt taattcttgg gagctacctg aatcgttttt tgaacgtgcc gatcgtttca
      721 ttgaatccgt aacggaaaat agtggcagat tttatgataa agaaaataaa gaaatcttat
      781 cgattggttt tgctatcagt ttcctacgcc agcaagtgtg tgctgtgaca atagattcaa
      841 aatttatcga agaaatcaaa aaacgtccta tttacaatta tgtcgaatca gcatgggaaa
      901 acactgattt ccaaacctat tataaaaaag aagaattcgc ctttattttg acactattca
      961 atctttgtaa ttatggtttc cattcttatc agttgattgc ggaagacttt caacagctac
     1021 accaagtgtt tattgacaat actcccgaaa taaaagaact agttgctacc tttgaatctc
     1081 acttcaatca agaattattc ggaaaccaac cgttcgaacg tgcgctgatt catctgatgc
     1141 gttcggcttg ggataactat caattattca tgccagaaaa attttatctt ttaaatgagg
     1201 aacagacaaa tttatataaa gaagtccaga caattttttc cagctggtcc agccagttac
     1261 cttatgatct acggttgaat cctaattgca tgcgggcttt tgtgatcgaa ttgagcggaa
     1321 ttctccgtct gacaaaagaa catctgacta tctatatcgt cacaaattcg gatgttcatt
     1381 atctgattta tcgggaagcc ttggaagctg taactacttt cgattttcaa gttgcaccaa
     1441 caatttattc aagtatatct gatataaaga agtatgcgca gcagtcctca aaccgggtat
     1501 tatgtgaacg tacattatat acaccagatg cggtccaata tgaaaatatt attcctattt
     1561 cgatcaatac gatcgatcga gctatcattt cagctgtgca aaacaaataa ggggctgtga
     1621 caaaaatcat gtcacagcct cttatttgtt gaagatgccc atttctgtaa caatctcttg
     1681 atacacgtca ggctcacaac ctcacttatt ttggacatct acgggtccga tctctttatt
     1741 taaaaaataa gaaatgatgg ttcggataac taccaacgcc gctagttgga aaatatcctg
     1801 caaggtaggt ttgataatcg attcgatgat cccagctgaa acaagaattt ccaaacttag
     1861 aagtatatag cctcccaaca tctttttaat agcattgttc tcgctgactc ggtcgctttg
     1921 cacttttgta tggacaaata aatatttcaa aaaatccttg attgatagac aaacacccca
     1981 aaccaataaa cagatagcaa agatatcaag tcccagtaca agtttttcga aatatggaag
     2041 aagaaactgc atcaactctg tcgtcatcct acctctcctc ttctttgttt ttctttgtct
     2101 tctatttcct gattcaagaa ataagaaatg actgttcgaa tgataataat aagtgcaagc
     2161 ttcaaaatat ctgtccaagt cggcttgata actgactcga tgatatcagc aacgactagt
     2221 acttccaagc ttaacaaaat ataacttgct agcagttttc ttgtatctgc attacgagta
     2281 ttacgttctg catagttttt cttgacatga gaccaatcaa aaagtttgaa tagaacaaga
     2341 acgatcccga caattaagat accgatagaa caaatattta aaatagcaat gatccattct
     2401 agaaattcaa ttaaatttga gcgaaacata tacgctacct actttctttt aatttgttcc
     2461 tattctttta ttgtaaaaga aagttacctt gttcgtctat ttaaaagttg ttctaatgat
     2521 aacggttcgc ttaaattttt ctttttcact ctcccatttt tctccctcca tccataaatc
     2581 gtggaagtat ccaaaacaac gtagcaagtt aaaataaggc ttagtccgtc atcagctttt
     2641 caaagaagca ctgtctcggt gctttttttg tacccaaatt tctaaaaata gaaccataca
     2701 cctcctcaaa tcttttcttc ttacctaccc tatttttatt tacaggaaaa tcagacactt
     2761 cttctttttt gtcaaaattt cctttttctt ctcgtcctat catttggcat tctaataaaa
     2821 acgaactatc cttggatata gaaagagaaa acaaggaggc gtttttcatg agtaaaaaat
     2881 taatcaaagt cggcatcggt ttaggtttgc ttgcccttgg cgctgcatat ctaggaaaaa
     2941 agacaggact attcgaagat gacagtcatt tatatgatga attcgaatca atctagcatc
     3001 ctatttagtt gaatcactac ggacatactt ggaagacatt ggaggaatca caatgagaaa
     3061 aagtaaagca ataatgattg gtgccggtat tgccaatatg gcagcggctg tttatttgat
     3121 tcaagaaggc aaatggaaag gggatcagat caccttttat tcattggatg atcacggttc
     3181 aaatgatggt gcaccgaccg acactgtagt ggatgaatat tggaataaaa accatccatt
     3241 agaaaaccaa aaaggctata ttgctcgagg cggtcgcatg cttaattacc gtacctatgt
     3301 agatttgatg gatctgttaa gtcgaatacc ttctgttact gagccaggga tgactgctga
     3361 agaagatacg agagattttg atgcaaaaca ccgaaccttt gacaaagcac gtttgatgga
     3421 aggtggcaaa ggaatcattg atggcggaaa actgggattc aataataaag accgtattct
     3481 tctgactaaa ctgattgcta tgcctgattc agaagaagaa aaactagaca atatcactat
     3541 cgaagaatat ttcaaagatg atccacactt ttttgaaaca aacttctggt ttatgtggga
     3601 aacaacattt gctttcagaa cacgtagttc tgctcaagaa ttgcgtcgct atatgcatca
     3661 aatgatttat gaattcactc aaatcgaaca tctagtgggc gtcaatcgaa cacgttacaa
     3721 tcaatacgaa agtattatgc ttcctttgat cgagtacttg aaagaacaag gatgcaaaat
     3781 cattttgaac cgccgtgtca ctgactggga attcaaagaa acaccgatgc aagatgaaat
     3841 cactgtgact ggtttgaaaa ttaccaatac actgactcaa gaagaagaat acgttgtggt
     3901 cgatgaagat acagcagtta ttttcactaa tgggtccatt acagattcag ctactttagg
     3961 agattacgaa acaccagctg tagaaaatat ggattatggt gcagcttcta gtctctggaa
     4021 aaaagccagt gaacgtttct acaacttggg aaatcctgac aaattctttg ctgatcgaga
     4081 tgcaagcgaa tgggtcagct ttaccctgac gacgaaaaac catttgttgt tgaatgaaat
     4141 cacccgtatc acgactcaag aaccaggaaa tgccttgaat tcatttattt caaccacacc
     4201 gatcacgccg ttaggccaaa aagatgtcaa tatgtctatt gtcgtgcatc atcaaccgca
     4261 ttttacgtct cagaaaccaa atgaaacagt tatttggggt tatttccttt atccaagacg
     4321 acgtggcgaa tttgtggata aacagtatat taaaatgaat ggaaaagaaa tgctagaaga
     4381 actgattgga caactttcaa aagtagatcc tggaccagtg aatattcgtg aaaaagaaac
     4441 agaaattttc gacagcgtaa taaataatat ccctgtctat atgccttatg cttccgcgtt
     4501 gttcaataat cgtgccaaaa gcgatcgacc aaaagtcatt cctaaacatt cgaccaatct
     4561 ggcctttaca ggagaatttg tcgagcagcc ttatcagatg atctttactg aacaaagtgc
     4621 tgtacgttct ggagaaatcg ctgctttcca ttttgcgggt attcctatgt cccgtcttgt
     4681 caaaacaccg cgttacgaca aagatattcc tactctagct cgtgccgcaa aaaaaatgtt
     4741 tgaataatca agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa caaccaggct
     4801 aaaacagctt cttatgtttt tgatttggtt ggacttatta ccgcagatgc aagcttttga
     4861 acaccgttta ccaagaggtt atgaaaaagc tgccctgcat caagtaataa gagcagccaa
     4921 gctaaaacag cttcttatgt ttttgacttg gttagactta ttaccgcaga tgcaagcttt
     4981 tgaacaccgt ttaccaagag gttatgaaaa aggcgtttag tttcgagtat gaagaaaaat
     5041 tttgtgaaaa tggttcctca cgtttttgca taaatttgac ttaataccga gaaactgatc
     5101 ccttctgtca taacctcttt ttatttatgt ctgtttcttt ttgaaaacaa ctattttttc
     5161 aacgtttact ctcttgccaa tccaacatca tctaacggat acaactattt caatgattac
     5221 cattacacta aaaaatcgga aacacacctc tccgaacaca aatacataag actatagaat
     5281 gtttcattta agaaaaaaag cgtttcatta tcaaaaaggt aagatctcct ttaaaatgaa
     5341 attatctgta gtactaataa tgcagacaat tttatgaatc tgaaaggagc atctccaatg
     5401 aaagcagtca cttggcaagg aaaacagaaa atggaaatca gaaacgtaga tgatccaaaa
     5461 atattagaac caacagatgc aatcatccgt atcacagcaa cagccatttg cggctccgat
     5521 ctgcatcttt accatcatgg tgaagcagtt ttggaaaaag ggtatgttgt aggacacgaa
     5581 ccaatgggaa tcgttgaaga agtgggatct caagttcaaa cattgaaaaa agggcaacgt
     5641 gtggttatcc cttttaatat tagttgtggt cattgtcatt tctgcctgaa tcacatggaa
     5701 agccaatgtg atgaatcaaa tccagatcag ttatatggcg ggcttttcgg atttggcaag
     5761 ttgaacggta atcattgggg tggtcaagcg gaatatctaa gagttcctta tgcagactct
     5821 acttcatttg ttgtaccaga taatgatctt cctgatgaaa aagttttatt tctatcagat
     5881 attttgccca cagcttattg gagcgttgaa aacgcaggag taaaaaaagg cgatacagtt
     5941 gtgattctag gttctggtcc agtcggtcta ttcgctcaaa aattcgctgt tatggctgga
     6001 gcagagcgcg taatcgcagt agatccagta cagcaccgtc tagataaagc ggctaattac
     6061 aatggggttg aaacttattt cttagaagac acggcacaag ctggaacaga attgtatgaa
     6121 ctggctaaag gtggcgcaga tgtcattatc gattgtgtag gaatggacgg attagagcct
     6181 gtcaaagaaa aagcgaaaaa tttagtaagc ttacaaagcg gcacaatctc tccattacag
     6241 atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt ttatatgact
     6301 ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt caagcatgga
     6361 caggcaccaa ttatccatct aatgccaaaa atttacgcaa tgattgcaga aggactattc
     6421 gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca agcatatgag
     6481 atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg aattcagtaa
     6541 aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga gatcgaaata
     6601 ggaaaagaag aagatatcga aatacgagga cgtcgcttcc gcttctattt ccaaaatcgt
     6661 tacacattga tctcactggc tgtcgattta ttaaccggga ttttctatat ttttggaagc
     6721 cttgcttcct taactaaaat ccccgatcga tatggcacct atttttattt ggctggtgct
     6781 attttcttga cgattcgtcc tattctcaga atcgtaagga acatttttat ttacgacgaa
     6841 aaaaaagcaa tgaagagaac aagcaaaaaa aaagaggcat gagaattttt caaatctcat
     6901 gcctcttttt tcaccctatc gtatcacttt gatacagacg agcggtcgtc ccactttctt
     6961 ccttgaccat tgtcaaaaat gtccactcgt atcgttcata aaacgtggta tgatctgtaa
     7021 ttaagtaaag tttttcgtac ccaagttgat gcatttcttt tctgatttcc gctaatatcc
     7081 gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa agatttggtg
     7141 tcagatcagg gcggttatgg aagtcgtttt caatgacgcc cgctcctccg acgatggttt
     7201 ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg attccagtac
     7261 gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac caattcgcgc
     7321 tttgttttac taattctggg tgttctctta atttgatcca gttatatgta accaatgttt
     7381 aaacctccga ctaaaataaa acgtttacaa aaattataca agtctttatg aaaattagca
     7441 atgacaacaa tagtgatgta aaaaaaaaaa cggaaaacaa tcacttgttc tccgtttttt
     7501 gattaatcaa gcatctaaag cttcttttct tctttcttgg atcgtagcta ccttgacgaa
     7561 cggtagatag atcaaaatag aaagaaccaa attgacagcg gctagtacac cacctgcaat
     7621 actttttgtt gccaatacac cgccaataat tggtggagtt acccatggag gcataacggt
     7681 agctgctggc actaaacctg tagaagtcgc aaagtaagca acactaacta agaccattgg
     7741 tgtcaaaata aatggaatga acatgatcgg gttcaacacg ataggtaacc caaacatcgt
     7801 tggttcatta atattgaaga cacctggcgc aatcgacaag tttgttacaa ccatatatgg
     7861 tttgttttta cgtcctacta aataaatagc taacagtaaa cctaaagttg cacctgttcc
     7921 tcctaagttg acaaagctgt caaagaaagg tttgttcacg ataaacggtg cgctatgtcc
     7981 agctgcgatt gcattaacgt ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg
     8041 atcgaccata ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga taaatgcaag
     8101 cagtaaggca gatggataag agtttgcaag tcccataaat ggttcttgga ccactgtata
     8161 gaaagaacct acgatatcat caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa
     8221 cgcagagata gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg
     8281 cacaccatca ggcattttga tgatcaattt ttcatttccg cttaaacgta caaagatttc
     8341 tgttgaaata atcccaacaa taatagcaat aaacaaaccg tttgagctca tacctaatgc
     8401 tccgcctaaa gcgaagaaag agcctaaaga aatcacacct gcggaaacac cgtcttttcg
     8461 gtagccgtta gctaaatgat aagcaagcaa gaaagcaatc aagacagaaa gaatggcaaa
     8521 tgtaccgttc caagcagcag ccccgaatcc tttccatgat tcaccaccaa aaattgagtt
     8581 catcaattct tggaacccgg gaatcggtaa gttattgatc attactgcta atgctcctaa
     8641 gatcattaac ggcatactca ccataaatga gtcccgaatc gcaactaaat gccgttgtgc
     8701 accaattttt gatgctacag gtataaaatg tttctccata aatgcaacaa atttatccat
     8761 aaatcttccc tcttttcttt actgtagatt acgcgttcaa tcgacgatac agatcaatga
     8821 tctcttttgc taaatctgta aaagctatag atgtcatcag atgatcttga ctgtggaccg
     8881 tcaaaagcgt gacttcaacg tgatttcctt gtgcttcttg tgtcagcatc tctgtttgag
     8941 agtgatgtgc ttggactaaa gattcctctg catctttgat tttttcatct gctaaagtga
     9001 aatcaccttt tttcgcagca gcaatcgctt ccattgcatc gctttttgca tttccgccaa
     9061 acatgatcag acccatgatg gcttctagat ttttttgatc ttccatttat tgtatcctcc
     9121 gataattttt attatttgtt tattagtttt tctgcttggt cgagtacttt ttcaccattc
     9181 atcatgccat agtcagccat attgattaca tctaaaggaa tgcctttagg tgctagcttt
     9241 tcagcaaatt gattttgcat aaagcgtact tgcggtccta aaagtaaaac gtctacattt
     9301 ttagattcta gttgattatc cgcatctgaa gcagatacag caaagatgtc tgcttccatt
     9361 ccttttgctt ctgctgcctt ttgcattttt gtgactagga gacttgtact cattccagct
     9421 gaacatacaa gcatgattgt tttcttttcc attttaaaca cgttcctttc tatacttaca
     9481 cttgtatata agcaagtagc gtgccaactt taaaagcgct ttaaaaagtt gatatcatca
     9541 catttaaggt ctataccaag ttgcatacac actaaaaaag aaagcgcaca ctaaacacac
     9601 aaattaattt ttattacctt ttttctttta acgtgcacaa aaaaagttgt gacacaaaac
     9661 ttgtcacaac ttttttcaaa taaacggtat tcaaaagctt gcatctgcgg taataagtcc
     9721 aaccaagtta aaaacataag atgttgtttt tactttgcta ttcttattac ttgatgcagg
     9781 acagcttttt cacaacctct caataaacgg tgttcaatca gctgaccctg ggtattagct
     9841 caaaacgctg gattcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct
     9901 acaaaaaact tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat
     9961 caaagtctga taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc
    10021 gattcgaact aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa
    10081 tgcccataac atatagcctt cgcaatttgc gccttcttct gttgctttga tcaagtaatg
    10141 caaatgctgt ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat
    10201 atactgttct tcatattctc ttcccatacc gttttctgtt atcagccaag ggatattatg
    10261 ataattttct tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc
    10321 cctggaatta ttcattttct tcccaggtaa atcaaagact tcataatatc gttcaggatg
    10381 gaaaggtgtc tcttcattcc attgataacg aggggcgcga acgcgtttag gataatattg
    10441 attgattcca aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg
    10501 atcgaaataa atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtatccttt
    10561 taccatcgga tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg
    10621 gtcttctgga gaattggatc gagcatagac catttcagga tttaaaatac agccaatcct
    10681 tccaccataa tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg
    10741 ataattccac atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa
    10801 atagcaacgc gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc
    10861 accgtaacga tcaaaggcaa tttgagcata cttagcataa aaatcaacta cttttcttga
    10921 agaccagcca tcatattttt ccaaaagaaa agctgggact tcataatgtt ccaaacaaat
    10981 catcggttct acgtctgctt cgatcaaaga gtcgatcatt tcacttatat gctgagcata
    11041 ttcttcatct actatacagt tctcataatc agtaaaaaaa cgagcccaat tgatagaagt
    11101 ccgataatgt gtcagatgga tggatttcat cagatccaca tcctgctggt attgttccat
    11161 aaaattagtt gctacggctg ggccataccc attatgccaa acaaaatgtt catttttata
    11221 ccagctatct ataaacgaat cctgtccttc tttttttcct ttccaacctt ccgtttgcca
    11281 agcagaagat gcagcaccaa gaataaaatt ttttggaata gtaattttca tgatttcctc
    11341 ctgtttttta gatcccatca ttttccacac gatttgctac ttttacaaat ggcagataga
    11401 tcaaaataga aacaataata caaacaagtt gcgtaataac tgcaccgata tttcctgctg
    11461 ttgccagata agcattgacg atcggcggca ttggccaagg gaccattaca actgctttcg
    11521 ccgcaaatcc taaagcggtt gcaaaataac caatcgttcc agtgataaga ggcgttaaga
    11581 taaacggaat agctaaaatt ggattcagca tgatcggcat accaaaaata actggttcat
    11641 tgatgttgaa gatcccagga gcaagggata acttggtgat ttgtttcata tcttcccgtt
    11701 ttccaactaa caatactgca atcagtaaac cgatcgtgac tccagacccg cccatactca
    11761 tatacatatc ccaaaatggc atagtaataa tgttcggtac ttcttttcca gcttcaaaag
    11821 cttccgtatt tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt
    11881 gatttccatg gataccaatc acccaaaaga cttgcgcaat aaacatcaat agcaaaatac
    11941 ccggtaaccc ttgtacgaca ccttctaatg ggcgttgtac gacattgtaa atgatatcat
    12001 aaaggtacat tcctgtaagt tctttgatga taaatcccgc agccgcgata cccgatacag
    12061 tcagaatcgt cgggaataaa gcagaaaaac tagcagaaac attcgttggc acggtatcag
    12121 gcattctcag ctgtagtttc ttctgtttcc tcaaccagca ataaagttca atagaaagga
    12181 tggagaccaa cattcccaaa aataaccctt tcgtatctgt atattgttta gccaatacgt
    12241 tttctactat aacagtctga ttttcattca ctaattcata aacagttgga ttaacagata
    12301 aataagacat cactgcgatg ataccaggga atacaccatc cactttattc agcttggcta
    12361 attcgatccc tatcagaaaa acagcataga tggtcaagaa acttagtgtg acatagctga
    12421 tggcagatgc gataggcttt aattcttcta aaaaacgcaa gaaacttatc tgtgctaagc
    12481 cattttccga gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc gtaataatta
    12541 ccggaatcaa tgcagcaaat gcgtttttta tcaccatgat ataccttaaa ttattgattc
    12601 tcgttgccac gttccctaaa acattggcta atttatccat aaaactcatt ccagatcccc
    12661 tcattcctgc ttcttctcct tgacgtcatc tctttttgtc tattagtcag cgcttacatt
    12721 tcgatgaaca gaaactattt actcctcttt tttaccaaat ataaaacaaa aattcatctg
    12781 atgtatttat cataaaatac atcagatgaa ctgtcaatta gtttcttttt ctcctattat
    12841 tttctgtaat tctctccgat ttattgccat atggacagtc attgcatcaa acgcagcaag
    12901 tgcattccgc ctttcgatgg cctgaacgat ctctgtatga atatcgatcg tctcgatttt
    12961 cagatgctgg atatcataat ttttattaaa caaagcaatt gattcattaa tgattgggat
    13021 aatatgcagc aaggctacgt ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc
    13081 taattgaaca tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt gcgttaattt
    13141 tttcatttgg acgatttgat tcttcgttgc atattccgct gccaaacctg ccatcttagg
    13201 ctccaataaa tatctcagtt caaataagtc tcgtatcatc cgatcctgat cttcaatcaa
    13261 agaaaaaccg agtgggtcat tggcaatccc tcgcttatca ctgacaaatg tccccgctcc
    13321 ttgccgaact tcaaggatat tcctggaagc tagagcccgc acagcttctc gcaccgtgct
    13381 tcgccccacc tctaaataat cggacaattc atattcattc ggcagtttat ctcctacttg
    13441 caactgcatt tcctttaaat atctaaggat cttgtcagta gttacttcta ctagggtttt
    13501 attttcttcc aaaccacata cctccttttc atctgatgta ttttttcgta attattataa
    13561 cacgtttgaa tcatctgatg attttttgta tacaaaattg attaatccgt tcatagacat
    13621 acaaacgaag aagatattta ccataaaaaa gactaggata aaattcactc ctagccttcg
    13681 atcattttta ttttgaacga caaaaaatat gatgttcaat aacagacgat cttcattcga
    13741 ttcttgatgt catcttttgt tttttttaat atatggataa aaagtttgat tacatcgttt
    13801 ctattctaga atttggtcga ttctcaattc ttcttctggt gagaaatcta aattatccat
    13861 cattcgaaca ctttcttgta actgacttaa ccgacttgct ccgaccagta cacttgtaac
    13921 agatttttgt cgcaaattcc atgcaagggc catttgcgct aatgattgtc ctcgtgatac
    13981 ggcgattgtt tgcagtgctt tgattttttc cagagttgat ccaacttgtt cttctgaaag
    14041 gaatggtatt tccttacgat gtgctctaga atcttcagga ataccatgta gataacgatt
    14101 tgtcagcaac ccttgagcaa gcggactgaa cgtgattgcc cctagccctt cttcttctaa
    14161 tactggagat agatcgtctt ctagtagtgc acgagaaaac atattgtagc gcatctgatg
    14221 aataatgaac ggtgcttcct ttctttttaa aatttcagtc attttttttg tatcttctcc
    14281 attatagttg gatataccaa tatataatgc ttttccttgt cttacaagtt gcatcaaagc
    14341 ttctgctgtt tcttccaaag gtgtatcagg gtctgggcga tgatgataga agatgtcaac
    14401 ataatctagc cccattcttt ggagactttg gtcacaactt gaaatgatgg atttacgaga
    14461 gccccattcc ccatatggcc cttcccacat atgataacct gctttgctag aaataatcag
    14521 ttcatcacgg taggcttgaa aatcttctct aaaaatacgc ccaaagtttt tctctgcagc
    14581 tccagcaggg cctccataat tattcgcaag gtcgaaatgg gtaattccca tgtcgaatgc
    14641 gcctcttaaa atctctcttt gattatggat aggatcataa tcaccaaaat tttgccataa
    14701 tccgagagat aaaatcggta atttcaaacc tgaatgaccg gatttacgat attccatttt
    14761 ttcataacgt gcactatctg caatatacaa tttttctcct cctcatcaaa tctttttaaa
    14821 acgctttctt ttttctattt ttagtttact acattttaaa gaaaaggagt taatcaaaat
    14881 gattttttcg tatatttttt tgccatttgt tttttactcg ttgatagatc agaaattgat
    14941 tacgtgcttg ctggattttt ttataacgtt tcggttgttt tttgtaaaat tgctgatgat
    15001 agttttctgc tggccaaaac gtaccggctg gttcgatttt tgtgacgatt ggttggtgga
    15061 aagttcctga actgtctagt ttctgttttg attgttccgc taattctttt tgtcgttcga
    15121 cttgataaaa aatcactgga cgatattgct tccctctatc ttgaaattgt ccaaatgtat
    15181 ctgtgggatc agtaatttgc caatagattg tcagcaactc gctataactt atttctcttg
    15241 tgtcataaat gatctccaca gcttccacat gacctgtgta accaccactt acttgatcat
    15301 aatttggttt ttcaacatgt ccgcccgtgt atcctgacaa aacagatagg atcccttttt
    15361 tcgattcaaa cggctcgacc atacaccaga aacatccccc tgcaaatact gcacgttctt
    15421 gatagtcagc atcttgcatg gcatgcttgg aaaagtcata tttttgctcc ttatcaaatc
    15481 cttccgtaat caataaataa aagtccatta catcaggcgt cagattcatt cggatagcta
    15541 atggacgtag tgttgcttct agttttgata actgttcttt aacggatata ttttctctta
    15601 tgtcattctt tgtctgaatc aatacttttc gttcccaatc tcgtgtattc ggattcaaaa
    15661 tcagattata aagtgtttga atgaatattt gttcctcatc catagattct cctcctttcc
    15721 gaagaagaca agctagtgac tttagctgta atttatcata aagtgaggaa ataagcgatt
    15781 acttcatccc cctacagatt tttcgtataa aaaagagaga atccttatcg acagattctc
    15841 ctttttaatc aatttatttt ataaatgaaa agttaattta ccttttatgg aaa
//
LOCUS       DADVXK010000064        15725 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.065, whole genome shotgun sequence.
ACCESSION   DADVXK010000064 DADVXK010000000
VERSION     DADVXK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.065"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1..330)
                     /locus_tag="KB909_001893"
     CDS             complement(1..330)
                     /locus_tag="KB909_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBB6837912.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            507..1235
                     /gene="sfsA"
                     /locus_tag="KB909_001894"
     CDS             507..1235
                     /gene="sfsA"
                     /locus_tag="KB909_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBB6837913.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            1251..2264
                     /locus_tag="KB909_001895"
     CDS             1251..2264
                     /locus_tag="KB909_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6837914.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            2264..3541
                     /locus_tag="KB909_001896"
     CDS             2264..3541
                     /locus_tag="KB909_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6837915.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            3604..6306
                     /locus_tag="KB909_001897"
     CDS             3604..6306
                     /locus_tag="KB909_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6837916.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            6458..6775
                     /locus_tag="KB909_001898"
     CDS             6458..6775
                     /locus_tag="KB909_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837917.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            6805..7125
                     /locus_tag="KB909_001899"
     CDS             6805..7125
                     /locus_tag="KB909_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6837918.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            7233..8693
                     /locus_tag="KB909_001900"
     CDS             7233..8693
                     /locus_tag="KB909_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837919.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            8761..8982
                     /locus_tag="KB909_001901"
     CDS             8761..8982
                     /locus_tag="KB909_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837920.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            9013..9195
                     /locus_tag="KB909_001902"
     CDS             9013..9195
                     /locus_tag="KB909_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBB6837921.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            9195..9608
                     /locus_tag="KB909_001903"
     CDS             9195..9608
                     /locus_tag="KB909_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBB6837922.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            9731..10912
                     /locus_tag="KB909_001904"
     CDS             9731..10912
                     /locus_tag="KB909_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837923.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(10983..11147)
                     /locus_tag="KB909_001905"
     CDS             complement(10983..11147)
                     /locus_tag="KB909_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837924.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            11301..11374
                     /locus_tag="KB909_001906"
     tRNA            11301..11374
                     /locus_tag="KB909_001906"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11335..11337,aa:Arg,seq:cct)
     gene            complement(11443..12582)
                     /locus_tag="KB909_001907"
     CDS             complement(11443..12582)
                     /locus_tag="KB909_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6837925.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(12881..13516)
                     /locus_tag="KB909_001908"
     CDS             complement(12881..13516)
                     /locus_tag="KB909_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837926.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(13629..14264)
                     /locus_tag="KB909_001909"
     CDS             complement(13629..14264)
                     /locus_tag="KB909_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBB6837927.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(14298..14759)
                     /locus_tag="KB909_001910"
     CDS             complement(14298..14759)
                     /locus_tag="KB909_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBB6837928.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(14889..15320)
                     /locus_tag="KB909_001911"
     CDS             complement(14889..15320)
                     /locus_tag="KB909_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6837929.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(15338..15658)
                     /locus_tag="KB909_001912"
     CDS             complement(15338..15658)
                     /locus_tag="KB909_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6837930.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
BASE COUNT         5022 a         2655 c         3034 g         5014 t
ORIGIN      
        1 ctatttttca gataacaact tatatgaagt gtctgcagat tcgtcataaa gagtttgttc
       61 gggataagaa aagataagat aaaaaccata ctgatcacgt acgactaaac gatattcatc
      121 tatttctacc acagatgtgc caagagactg accgttgatc aaaaacgtgt aatcagatgt
      181 aatctgtaat tgttgttttt gctggctatc actaaagaac catgtacctt gatactttga
      241 gagtccttct gacttttccg cttgtttttt ctttttcaag taaataaaac ttgagagaac
      301 ggtaatgagt gaaccaagaa aatagatcat tttttttatc accaaatcac tcctttatga
      361 gaaaataatc gcatagacat attctttctt ctttatttca ttgtaccgaa taaaagctaa
      421 aatttctcta agactttcga ctggtttttt tactgttttt ctacaaatta tgataggata
      481 catagtagga agaaaggtga cataatttga agtatcagca agtggaaata gcttttttta
      541 ttgaccgccc gaatcggttt atagcacatt gtatgaaaaa agacggagaa ataattattg
      601 cgcatgtcaa aaatacaggt agaggaaaag aggtcctgat accaggcgct gaagtggcta
      661 ttgtatttgc tcctggacct aaacggaaaa ccgcctatga tctgattgct gtaaaaaaga
      721 agggtgactg gtttaatatc gatagtcaat tgcctaatcg gctggcaatt gatggtattt
      781 tagacggcac gatcctttta ccaggattaa ctggtccatt tacggtatac aagcgtgaag
      841 taacttatct tcactccaaa tttgatattt atttagagac ggtggtcgga caaaaagcat
      901 ttgttgaagt caaaggtatg acacttgaaa ataaagcgat tggtgctttt cctgatgcgc
      961 ccacactcag aggattgaaa catataggag aattaacgta tgccgcacaa gatggttatg
     1021 ccgcttatgt cttgtttatt gctcagttcg aacatcttca tctggcaacg atccatgaag
     1081 aaatgcaacc agcactagct gatatggttc gacatgcgca gcaaagcgga gttcaaatcc
     1141 tcgcctataa ttgtcaagta tcggcagatg aggtaactgt caagcaggcc attccatttg
     1201 atgtagatat cccttttgaa gatcctatac aatagaaaga aggtaaaata atgatcaact
     1261 taggtattat cggaacaaat tggattactc atcaatttgt ccaagcagct ttaagcacaa
     1321 aaaaatatga attgacagcg gtatattcta gacatttgga aaaagcacag gaatttggtt
     1381 ctcattatga aggggatatc gaattcgcaa cagatttgaa gacttttttc aatattactc
     1441 atatggacac catttatatt gcttctccga atagtcttca ctttagtcaa gctaagcaag
     1501 caattttggc aggaaaaaat gtgatagttg aaaagccagc tttttcgacg ccaaaagaaa
     1561 tggatgaaat catccatttg gcaaatgaac acaatgtgta tttttttgaa gcagcaagaa
     1621 atatccatga atcaggtttt aaaaagattg ccgattactt accattaaaa gacgagataa
     1681 tcggtgcaaa tttcagctat atgaaatatt cttcgcgcta tgaccaagta ttagatggag
     1741 aagaaccgaa tatcttctcg actcatttct caggtggtgc attgatggat ttaggtgttt
     1801 accttgtata tgcagctgtt gcttggtttg gaatgccaaa agaagtccat tatttcccaa
     1861 gaaagatttc tactggtgta gatggtcttg gatgggggat cttacgttat gagaattttg
     1921 atgtatcgat ccagccaggt aaaatcggtg attcttattt accgtcagag atttattttg
     1981 actcaggaac gctagtgatg aatggagtca atgcaattga acaagcacaa tttcatgatc
     2041 gcgcgcataa agaaatcatt gatttggcgg taacagctgc agaaaatcca atggcagatg
     2101 aagcagagga ttttgccaat gtcatggctc atccgaaaga tccagcttgg ggattgttgt
     2161 atgaagagtg gatcgagcta gctagaaatg tgaaccaagt gatttatgat ttaagaaaaa
     2221 atggcggcat caaattcgat gcagataatg aggaagattt ttaatgaacg aatttgtaca
     2281 agtatttccc gaaaattggc agaaaaaata tgaggataaa gggtttatct caccttctct
     2341 tattcaacga gcagtttttc agccactaag taataaacaa agtatagtag cggtttctcc
     2401 tacaggttca ggtaaaacac tggcttatct ttggcctcta ctactaaacg tggaaccagg
     2461 tgaagcaagt gcgttggtca tttttgcttc ttctcaagaa ctagctattc aagtagcaga
     2521 tgttgcacgt gaatggggaa aagacaaaga gttgaaagtc caatctttgg tgggcggagc
     2581 caacgtcaaa cgtcagattg agggtttgaa ggaaaaacca gaaatcttga ttggtacacc
     2641 aggaagaata ttggaattga tgaaagcaaa aaaaataaaa gcacatcaag tgaaaacaat
     2701 ggtatttgat gaagcagacc agctatttga cgctgggaac agccaaatca ttgatcaaat
     2761 tcttcatcaa gctccaacag agtatcagct agcttttttt tcagcgacag cagatcgttc
     2821 ccttgaaagc attgaaaaaa tcactgggaa aacgtttgag acaattgacg tgacagcaga
     2881 ggacgattct cgaaaaggac tgagacatta ctttttacgt gtaccgatac gaaagaaaga
     2941 tgactacttg agacgtctca cgcatataga agattttcat ggtctgattt tctttaatca
     3001 actgactgaa ttaggcgtaa tggaagaaaa attgctgtat agaggtgtac cggtaggaag
     3061 tctggcctct gatcagaaca agctactccg aaaagcagcg ctagaacaat tcaaaaagaa
     3121 aatggtcaga gcacttttga ccacagatgt ggcggctaga ggtttagata ttacaggtct
     3181 tccttatgta gtgaatgcag aagttccgtt aagtgaagaa gcttatttgc atcgttcggg
     3241 aagaactggt cgaatgggta atgaaggaat agtaattaca ctcgtacaag ataataatct
     3301 aagagattta aaacggcttt tacgtccatc aaatataaca cttgaagaga tttttttata
     3361 cggaggtaag ctgcaaactg agcagccaac caaagaagat gcagctcctg cagtaaataa
     3421 aaagtatgcg aaaacttttt ctggaaagga gcagaaccca gaatataaca aagaaaaaat
     3481 aagaaaaaaa gttaaaaata aatcaaaaaa agagagaaat aaaggagcaa ggcgcaaata
     3541 agcgcctttt tatgctatga ttatgaaaac gggaacaaaa ttggttgcca gaggaggggt
     3601 tatgtgaaag aacgtcaaga agagatcttg cagctattga cagaaaacca acaaggattg
     3661 acagcaagtg atgtagctga gcgcttaact atcgatcgaa gcaatgcaag ccgatattta
     3721 agtgaactat acaaggccca tcatattgta aaaaccgctg gccgaccagt cgtttactct
     3781 ttgccaacgg aaaagtcaaa atctgatgaa gtgcatgtcg actcttctac gcaagtgact
     3841 tttgaaacac tcgttggaga aaatgattct ttaaaagtca gcatacagca ggcaaaagct
     3901 gcgattcttt atccaccgcg ggggttgcat acgattattt ttggagaaac tggtacaggg
     3961 aagtcgatgt ttgctgaatg tatgtatcat tttgcaatcg attcagagat gctttctgca
     4021 gatgcgccat ttgtttcttt caattgtgcg gattatgctc aaaatccgca actgctcttt
     4081 ggacacatct ttgggatcaa aaaaggggct tacacaggag cagctcaaga tagtcccggt
     4141 ctaatagcca aagcagacgg cggtatattg tttttagatg agatccaccg tttaccgccg
     4201 gaagggcagg aaatgctgtt tactttcatt gataaaggta tttaccgtcc gcttggagaa
     4261 agtgcacaag tacatgaagc atctgttcag atcattgggg cgacgactga atcttcagaa
     4321 agtttcttat ctacgttcaa tcgacggatt cctatggcaa tcaccttgcc gaatcttgct
     4381 tcacgttcac tggatgagcg ttatgaaatc atctctcttt ttatcaaaca agaagcgaat
     4441 cgtttgaatc aacgtatcga tatcgaaaaa gaagcgattc ttgccttcat gctttatgat
     4501 gcggaaggaa atatcggtca agtgaaacga gacttgaaac tagtctgtgc aaaatctttt
     4561 ttacattacc gtactcatca tgagaaaaag ctaatcattc gaaaagaaga actttccctt
     4621 caagtacaaa aaggattact gaaaatcaag gaaataccgg aacgtctcga ccgattcatg
     4681 gacagcaaaa gtcagtattt gacatttgaa ccaggatttg ctgatgttgt ctggtcacaa
     4741 gatccagaac gaaacatgca ggtctataac gatattgagg aaaaagtcac ttctctttcc
     4801 gaaaccggtg tggagaacat tgatctagag accctcattt caaaagatgt ggatgcttat
     4861 ttccagacat atgtcaaaga attgactaaa agttcgattc ccaaagatct tttgccagat
     4921 gaaatctggc ggttaaccaa tcaattgtat gatgtggctg aaaaacggtt agaccgtatt
     4981 tataatgaaa aagctcgttt tgcttttgct ttgcatctgc aaagtacatt ggatcgtgtg
     5041 agagaaggtc atatgatcgt ccacccagat ttgaataacg tacggaaaaa ttttaagagg
     5101 gaattccagg tagcaatcga tctttcaacg atcattgaag aagaagaaca agttgagatt
     5161 ccttttgatg aaatcggctt tattagtatg tttctttcta tcaatctagg agaaagtgag
     5221 cctgttaaag aaaacaaagt agatgttctc atattgatgc acggcagaca gactgcttca
     5281 agcatgttgg agatggcaca agaactatta ggaacaaaag tagggaaagc ttttaatatg
     5341 ccactggtta tggaagttca aacaatgtat gaagaagtgt tacaatatgt caaaaactat
     5401 caagagcatt tgacgaatgg cctactcttg ttaacagata tgggatcatt aaacaccttc
     5461 agtgatttga tttatgaaga gactggcatt cggacgaaag ctatcacgat gacaagtacc
     5521 atgattgtga tagaagcgat acggatggca agtgttggaa gaagcttaga agatatttat
     5581 caaaatatcc agctttcctt tgaatcgatc gtacgtgatc agttcaaagc ggaaaagtct
     5641 gaaactttac agcgtaaaaa agccgtaatc gtgacatgct ttactggtga aggagtagct
     5701 gccaaattat atcagcgtat tatgccagtg attaatcaaa ataaggtaga actgatccag
     5761 atgcagtttt tagaacgtga atcattcaaa aaacacatcg atgccttatt ggaagaatat
     5821 gagatcaaag caattgcggg aacagttgat gttgattatc aaaatatccc atttttttca
     5881 gcctatgacg tttttgatga tgaaaaacta aatattttaa agcgtatagc tgatgatgag
     5941 atcccgacag ctaaaattgt cgattcactt gctggatcat taagcgatgt cttttctatt
     6001 gatgaactga tccgttcatt gcaaaagaca gttcagcaga tccagaccga tttgtcgatt
     6061 atcgtggaac ctggagtaga tactggaatc gttatccatt tagccttcat gttagacgga
     6121 ttgatcaaac aagaaagcca tcggcaattt gagaaactgt ctattttctc aaaaatttat
     6181 cgtttggaaa tggatatcgt tcgggcaaac ttgatggcac tagaacgaaa atatcaggta
     6241 aaaattccag aagatgatat cgcatttctt acacaaatgt ttcttgaaaa taaaataaaa
     6301 aaatgaacac actaatcata ctgtttacac actaaacatc tgtgtgcgca ctataaaaaa
     6361 gagctaaaaa gcatgaaaac gctatttcag ctcttttttt tattggcatg cttcttgcgt
     6421 tatataaaag tgtaaaaaaa taaaaggagt gttaaaaatg gcaaaaaaaa caatcatgtt
     6481 agtttgttca gcagggatga gtacgagttt attggtcaca aaaatgcaaa aagcagcaga
     6541 agaaaaaggg atggaagccg atatttttgc ggtctctgcc tcagatgcag ataataattt
     6601 agaatctaag aatgtcgatg tattattatt aggtcctcaa gtacgtttca tgaaagctca
     6661 atttgaacaa aaacttgcgc ctaaaggtat tccattagat gtcatcaata tgcaagacta
     6721 tggcatgatg aacggagaaa aagttcttgc acaagcagaa aatctaatga aataaatcaa
     6781 gtatgcagtt gggggtataa caacgtggaa gatcaacaaa atctagaagc catcatgggg
     6841 ttaatcatgt ttggcggtaa tgcaaagagc gatgcaatgg aagcgattgc ggctgctaaa
     6901 atcggtgatt ttgagttagc ggataggaaa atcgctgatg cagaagaatc acttatacaa
     6961 gcgcatcatg cacaaacaga catgttgaca caagaagcac aaggaaatca tatgcaagtg
     7021 acattattga ctgttcacag tcaagatcac ttaatgacat ctattgcgtt tactgattta
     7081 gcaaaagaaa tcatcgaact ttatcgtcgc gtatacagcg aataaataca acttcttttt
     7141 tgaacggaag aagaaaaatt tttgaacgga ttttttattt tgttataagg agaactctct
     7201 ttatataaaa aacttatagg aggaagtaaa aaatgaacgg actatcaagt tggatggaga
     7261 aatacatcct gccggttgcc gcaaaaatcg gagcgcaaaa acatttagtt gctttgcgtg
     7321 atgcttttat cggcatactg cccgcaacaa tggcgggatc agtcgctgta atgatcaatg
     7381 caattattcg tgatttaccg caacagttta acagtaccta tgctgacagt ttagcagcag
     7441 acaaaggaat ctttgccgta ttgaatgtca tcatcggaat caatggtttt gtctggaacg
     7501 gtacactagc aatcgccgga ttgatctttg ccttttcttg ggggtataat cttgcccgag
     7561 cttatggagt aaatgatcta gctgggggga tcgttggttt agctaccttg attcaaggta
     7621 tttcctttgg tccagcatta tcagcagcat tagatgtgaa tgttccttca aatgtcgcag
     7681 atgcaatcaa tagttctgag attggtgcaa cgattgcaga tggcacactg tcagttggat
     7741 tatggggttg gctaaaacta gatcatttga atggaaacgc ttattttaca gttatgatca
     7801 tgggagctat ttcagtcatt attttttgta aattgatgct tgccaacatt acgatcaaaa
     7861 tgcctgattc agtaccacca gcagtatcta aagcatttgc agccatttta ccagcgacga
     7921 tcgctttata cgtcattgct attatcaatt atatcgtagg tcgtgtagct gatgggcaac
     7981 tgatcattga tttggtgcaa aaatatattg cagaaccatt cctaggatta tctcaagggt
     8041 tgggagcagt attgatcgtc acagtatttg ttcaagtatt ctggttcttt ggtattcatg
     8101 gatcaaatgt attggcacca gtgctagagg gaatctgggg acaagcacaa ctaatcaata
     8161 ttgatatttt ccaaaaaggt tataacggaa aaactggtac accagccgtg ttagatgcaa
     8221 tcgaagatgg aaaagcttat atgtgggtcc gcggatcgtt cgatgctttt gcatggtttg
     8281 gcggatcagg cggaacgatc gtcttactga tagctatctt gattttctct aaacgtgcag
     8341 attatctaac agtagctaaa ttatccattg ggcctggtat cttcaatatc aacgaaccag
     8401 tgatgtttgg tctgccaatc gtattgaatg caatcatgtt tatcccattc ttgattgctc
     8461 cagtagtagc aacagcaatt ggatggacag ctacttatct tggcctagtc gctccggtat
     8521 cgcagcaagt cacatgggta gtaccgccgt tcttattgtc attcttagca acaggagcgg
     8581 attggcgggc accgatcgta acattagtat gtatggtcgt gactttcttg atttgggcac
     8641 catttgtcat ctctgcaaac aaaatggacc ctgccgcagg cgaacaacaa taagatgaac
     8701 gtgaggagcg ggacgcttta agtttcgttc ctcataatga attttcgagg aggaactgaa
     8761 atgattacaa ttgccagtgc aatgcaacaa gatgaaatca aagaattgtt agaaggatac
     8821 aatgaagaag gaatgacttt tacatttaaa gaaaaacaag gaatcaagct gttctttgaa
     8881 acaagtgcag aagatccgga agttgcggct aaaaaagcaa aggaactaat caaagcacag
     8941 ccttggggaa cagtccttta ttttcaatca acagctgttt agaaaatggt ttaaaaagat
     9001 aggatggttg agatgataaa aaacggttta tttttatgta gtattggttc tttgatcgtg
     9061 ttgtatagtt tgaatccaca ttcgcaaagg tatgatttgt atagtatggt cacaggtctt
     9121 tttctaacag gattaggaat ctatttcttc atgaagggga aaaaaagaga agaagcaaag
     9181 gagaaaaata actaatggaa atcacgaaaa aattaaatat tccagcatcg tttttttacg
     9241 ataaagttat ggactctgtc cttttcgatg tacgtaaagc gaccggcaaa tcagtaacta
     9301 gaaaacagct gaaaaatttg gagtacgtca aacaattctc gcaaaataac cgggctcgca
     9361 taaaaatcga agaagtcatt gaaaaccagt cttataagtt tcgtacatcg acaacgaaga
     9421 atgaattcgt cgttcattat caaatcaaac cattggacga ttcgacctgt gaggttcatt
     9481 acacagaaaa aatggagtct tatggcatgc ttcaaaagtt gaatgatatg cttttaggaa
     9541 caatcttgat gtattttaaa cggagacgtt tcaaaaaaat gctagatatg atcgaagcaa
     9601 cgtattaaat caatgaaaca tggtactatt tagttattga aaaatgaagt aagctagaag
     9661 gaatttttca taggaagata gatctttcct gcgaatcctc actagctttt ttgtaggaag
     9721 gggcagcaaa atgacaaaca aagtaagaga gctaggtgta tcttcgattg aggaaatgtt
     9781 tgatttagcc acttatgcat ttaatggggc agatacacct gaaaggcgag aacgttttcg
     9841 tacacttgcg gagaattctt ggaattacgg attttttgat gaggaggatc ggctaacaag
     9901 tcaagtcatg gcgacccctt ttccagtgaa tttttacgga caagagtacc taatggccgg
     9961 cattggctat gttgcttctt atccagaagc aaggggacaa ggcgggatca atcagatcat
    10021 ggaaaagatc cttgaagatt gccgtgatcg taaagtaagc ttatcttatc tggcgccatt
    10081 ctcctatccc ttctatcggc gctatggcta tgaacaatca tttgataaaa tcagttatca
    10141 actaaacagt cgtgatgtgc cgtttatcaa aaaaaaatct ggaaaaataa agcgtatgga
    10201 ttttgaagat gcaaaagctg caatcagaag aatttatgaa cagatgccgg aaaaccaacg
    10261 agctggtctg aagcgcgaag actggtggta tacgtataaa ttcaagcaaa aaggcaatta
    10321 ccagtttgct ttgcattttg atgataatga ggaagcaacg ggatatatcg tttatcagct
    10381 tgcaacgtct tcctttatta ttgcggagtg gggatttttg gatcatgatg ctttttgcag
    10441 ccttgttcgc ttcgtaagtt ctcacaatgg tgcttttgaa acatttgaat attcatgcgg
    10501 ctacggcggt aatgatcaaa attatctatt agaaaatcca tttgcttctg taatgatcac
    10561 accttatatg atggcgagga tcgtagatat ttctttgttt ttggaaaatt atccatttaa
    10621 aaagagacaa gctgcatttg ccctacaaat agaagaagat cattatgcga aatggaatga
    10681 aggaatcgtg gaagtaacaa tcgaaaatgg aaaaaatcat ctctcaaaag tagaacaaac
    10741 aaaactccca atcgttcgag gaagtatcca acatatcacg cagctattat tagggtatcg
    10801 taaagtggaa gagttggtat tccaagaaag aatacaggtg acaaaagaat atgaagaaac
    10861 gttaagctca atcttgccac agcaacagcc aattcttaat gactattttt gataaaaaac
    10921 gggtgatgac aatatttttg tcaccaccct tttgtttttc atttggcatt tgaaggaaaa
    10981 tgttaaagta aatcctcttt tttcgtaaat ttgaattttt tgttttcttt tgttttaggg
    11041 ttttcttttt tgtggtcttg gattgcttct ttcgtaatct tttcccgatt ttttttagat
    11101 gaatctaagc gttctgcgta tactttttct tttggcttat cattcattgg aaaggacctc
    11161 cctacattat ttcattctac ctctagttta tcatctgtta aggactagtg gaaacgtttt
    11221 gcctaactta taagctgatt tttttagcag ataagcttgc aagtaaaaaa caaacaagct
    11281 acaattgatt tattgaaatt gttcctgtag ctcagtagga tagagcaatc gcctcctaag
    11341 cgataggtcg ctggttcaat tccagtcagg aacgtataaa taacccctgt atcctttgcg
    11401 gtacaggggt ttgttttgta tttgtgccaa aaatgtgcca aactagttat catttttata
    11461 taaactatcg aacacagtat tgattttttc tttatcctga tcttcaagct ctcgaacaat
    11521 atgaagataa gtagacattg tagtttctaa actgctatgt cctaaacgtt tcgatacgct
    11581 aagtatattt actccttgat aaagtaaaat agatgcatgt gtatgcctta gtccatgcaa
    11641 agtaaattgc ttttcaatcc ctaattcttt taattttttg cgcaaatatt tgctgacggc
    11701 gtttgatgaa actaatccat tttttaagtt gaaaaaaaca aaattatgag ggtttttgat
    11761 ttcaaaattc tcgaataatt ctttttgatt gattttaaac ttttttaaga gatcaatcgt
    11821 atgtttatca atggaaattt tcctatttga agtttcgttt tttgtttttc cccattcatt
    11881 taatttataa ttccatgttt tattaatagt gatgatttga tcttcgaaat cgatatcttc
    11941 ccatgttaat cctagaagtt cagcaaatcg cattccagtg gcaccagcaa ctaacacgag
    12001 cataggagaa gagtactgcg cagaaaggtt ttcttctacg agtttcatta aagatttaaa
    12061 ttgatcataa tctaaatatt tatcttcttt tggcttcaat gaatcttttc ctttgattac
    12121 tgcttttcta gttggatcaa acggaattaa tccttcttct acggcatctt tcaacgacgc
    12181 tctaatatgg ttattaaact taataacggt agattttaca tggtctttag catacttatt
    12241 taaaaagcgt tgatatccca ctctatctaa atcagaaatc aataccgctg gcatatattt
    12301 ctttatgttc attaacgtat cttcgtattt tctataagtg ataggagata ctgttccttc
    12361 tttataaagt tgcatccaat cctcaaagta atctgataat aatagatttt tgcgatcccc
    12421 tttaaggcct ttgttcaagt tatattctaa ttcgttggcg gcatcttttg cttctccttt
    12481 tgtcttaaat cctgattttc ttatcttcgt gtattttccg tcatcttttt tgtatgaaat
    12541 ttcgtattgc caactatttc cacgtttgac taatcttgcc ataattgaat cagctctctt
    12601 tctctgatac aataggaact ataaagaagc ccattgtttg ggttttatta ttttttgcac
    12661 atcctttttg cttgccggcg caaggatgtg ctatttgtcg ttttaatggt ataattggat
    12721 gtgtattaga tcatccaatc agaggtgttt attatgatta aagtgatttt taaaagaata
    12781 actgaacttc cagagtttag attatttgtt gattattggt atgtctggtt ttttattgtt
    12841 gcattgctga taggtctaga tgtcatatta gaaagaaaac ttaagtaaga gttgagttaa
    12901 taaattgaat tcctaaatga gatattttgt agcccatatt ttgtttgccg acatcaccta
    12961 atactatgga gctaatcgtt ttttctaaca gaccaaaatc agataatcta tttaagctac
    13021 catctattag ctcttgtgaa tagccagaca tgctgatatt tccagtgaaa ttttcgtttc
    13081 cacgactcat taagcatgct aacaattgaa tctcaatcga tgttaattga ttcagtacaa
    13141 gaagataata ctcctcgtta tcccatgaag cgttgttaat tcgaagtaaa caattcttat
    13201 aaagattttt atacatatct attttatttt gtgcctttga tttttctacc tcgtcattta
    13261 tcccttcgaa tattccaatg agttggtcct tgttctctaa gttgaaaaca tcttctggaa
    13321 tttgatcgcg aatgttttct aatgattcgt ttaaattttt gtagaatttc tcgatgcgtt
    13381 tgaaacgctt ctcgttttta gacccaaaat aaagtgactg cacaacgcca ccaatataag
    13441 gaattgctcc aataccgcct tcaactatta attcaagata ttcttttttg gttagttttt
    13501 cattgctatt atccatagtt acctcctatt ttgtcatttc ctttacaagc attgtgactc
    13561 ctgatggcac tcttttgtat aggttttatt attgtgcaca atctaactct tagtggggcg
    13621 tggttcattt attttttact tactttacta ttaatcatat cccattgagc ataggatttt
    13681 tctatgttcg atcctcttga actaatttct cctgtaaaag ttactttatc gccctttgta
    13741 aaggtatcag cattgtttaa gtccttcgca aaaattacat atgaaacttt aggtgttgca
    13801 gaaatatcat tccaactttt atcatcgtac tctttgtctg ctataatggc tattctagta
    13861 gtcattgatt cgataacagt tccttcaaaa gtatatgttt taccactaat atatttagta
    13921 aaagctgtat tttgctcagt agctggagta atagaataat aactatctaa gaaagcaccc
    13981 cagtcatgat tatttgtctc taaaaattct tcaaattgag ttaggctttt attgctgctg
    14041 ttagatgtag tagtttgagt atcagatgat gagctttcct gtttgttatt gtcatttgcc
    14101 tcgtttgatg aggaaagcga gaaacctacg gtagtaaaaa taatcccgat aataaggaga
    14161 atcataggtg ttttcttatt tgtttttttg ataaatctta caattaacat gattaaacct
    14221 ataataaata aaacaatacc agtaaaacca aatataccgt ccattaatag atcctctttc
    14281 tcttttgata ttgaatatta taaaccaagc aattcttttt tcttaaaatc gaattcttct
    14341 tgattaataa tcccttcatc taacaactct ttatactttt taatttcatc tgcacttgaa
    14401 atttgtgttt ctttggaatt attatctaat atagattgtt gcttctctat atattttttt
    14461 aaattttcca tttcattcca atattttttt gtaaacataa cggtgttttc atctttcgtg
    14521 gccgctaata tacctccgcg actttcgttt ccgcctagca aggtaaattg tatataacca
    14581 ttactcatac ctggtttttt taattgtacg gctgatatat ttttaaaggg gatagttttt
    14641 tctcctttaa taccttgatt aactaaattt ataaatcctt ttctaataat tgaaatagaa
    14701 tcatcagtta ctttaatcaa ggtttttcct ggagatttta ttaaaatctc tttttccatt
    14761 ttttcttcct catttctgtg atatgatttt ttttgtagaa gctcatatat gaggaaagag
    14821 cccgtgttgc agcacgggct tttttaatgt tttgctgaaa tcggtttttt taataattct
    14881 tgatgtattc atacatattg ccttgcgtaa gaatattttt tcttaaaata gcattggcag
    14941 acagcataac aagtgtatct gagcttattc tgaatagaat aatactccat aaatttttcg
    15001 agattaaact gagattcatc agtcagttcg ttctcaatat agatatttaa taaaattaga
    15061 atagctattt tatctgcttc tgtttcaaat tttgagtgaa aagttgtaga agtatcgtac
    15121 aaaactgaaa attcaaaatg agaggcgctg aaatgtgcaa gttcatgaga taaatgaaag
    15181 gcttctgcag tttcaccgta tagattttca ttcaaaaaaa tgattctggg ttttggatag
    15241 tagaaaccag gctctttcat ctccatataa actactttca aattgtattc gctcaacatt
    15301 tctttcaatt tcaaatacat acaaaccatc actccaacta ttcattttcc tctaaagctt
    15361 tagcaattgc aatcgcttta cgcattgtct ccttagatat ttcttttcca tcaaaagaaa
    15421 aaacagtatc gtcttctgat aaatccacat gtttaggggt ttctctttct tctctaccta
    15481 gaaggtagtc tacagagaca tcgaaatagt cagcaatccg acttaattca tctgaattag
    15541 gagtattatt tttccacttt gctagataac cgttagaata tccaaaatta atttctaact
    15601 gccgtataga tatctttttc ctcttcgcca agtcttttat tatttcatag gtattcatcg
    15661 ataaaacaac ctttctaaat gtttacaaaa aaagtttaga aaaatacgca gaaataattt
    15721 gacta
//
LOCUS       DADVXK010000065        15572 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.066, whole genome shotgun sequence.
ACCESSION   DADVXK010000065 DADVXK010000000
VERSION     DADVXK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.066"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(123..500)
                     /locus_tag="KB909_001913"
     CDS             complement(123..500)
                     /locus_tag="KB909_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837931.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(800..1681)
                     /gene="galU"
                     /locus_tag="KB909_001914"
     CDS             complement(800..1681)
                     /gene="galU"
                     /locus_tag="KB909_001914"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6837932.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(1724..2743)
                     /locus_tag="KB909_001915"
     CDS             complement(1724..2743)
                     /locus_tag="KB909_001915"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6837933.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(3376..4380)
                     /locus_tag="KB909_001916"
     CDS             complement(3376..4380)
                     /locus_tag="KB909_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6837934.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(4393..5442)
                     /locus_tag="KB909_001917"
     CDS             complement(4393..5442)
                     /locus_tag="KB909_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6837935.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(5459..6280)
                     /locus_tag="KB909_001918"
     CDS             complement(5459..6280)
                     /locus_tag="KB909_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6837936.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(6267..7046)
                     /locus_tag="KB909_001919"
     CDS             complement(6267..7046)
                     /locus_tag="KB909_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6837937.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(7063..7533)
                     /locus_tag="KB909_001920"
     CDS             complement(7063..7533)
                     /locus_tag="KB909_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6837938.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(7545..7964)
                     /locus_tag="KB909_001921"
     CDS             complement(7545..7964)
                     /locus_tag="KB909_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBB6837939.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(8045..10822)
                     /locus_tag="KB909_001922"
     CDS             complement(8045..10822)
                     /locus_tag="KB909_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6837940.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            11013..11237
                     /locus_tag="KB909_001923"
     CDS             11013..11237
                     /locus_tag="KB909_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837941.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            12016..13731
                     /locus_tag="KB909_001924"
     CDS             12016..13731
                     /locus_tag="KB909_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837942.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            13734..15497
                     /locus_tag="KB909_001925"
     CDS             13734..15497
                     /locus_tag="KB909_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837943.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
BASE COUNT         4547 a         3215 c         2656 g         5154 t
ORIGIN      
        1 cattccttta aaaaagattc ttttatataa gtgaaaaaag cttttttcca ccaattaaat
       61 aaatctctca tctcaatagt ttatccatta ttttatcttt ttttgcgtat acctactaaa
      121 tattaccgtc ttcttctcgt tcttctactt tgttcgagag aatctgtact agaaaaagta
      181 gttgtatgtc taccttttct gcctatccga gactttcttt tcatatatgg gatataaatg
      241 attagataca gtacagcaaa aaataaagca aatacgcaag cttcccaact acctaacgcc
      301 aattcaacca tcaaggtagc aaccccaacg gatgctgcat accagataaa aatcagaaac
      361 gtttcttttt ttctgaccat gcgaaacatg ataaatagac taataagcaa tagtggcaac
      421 acaaatatcc aattgcttcc ttccatcagc cacttgagta tatcaagcag cgactgtgca
      481 acagcgacta attttcccat agtgaacaca cacctttttt tataattaaa aaattcgcct
      541 ttttattcta ctatgaatct tctggcttgg ctttcatttc tcttatgtaa tcattttctt
      601 ttatacaact taaaaaaaaa ttaaaccatt agcataatat tttctgaatc tattcacgaa
      661 agtctttttc tatctttcgt tttccacgac tcaactgatc tagagtcaaa aaactaaaac
      721 gacagttgcg caaatgacgc acaagctgcc gctttaataa caaatagcct ttcattctca
      781 gcaggccact tatttccagt taactttctg ttcttagctt tttactcaac tggataatat
      841 atgcacttaa tgaagtccca atttccgaat gttgaagtcc atattcaata tttgtcttca
      901 tatatcctaa cttatcgcct acgtcgtatc tttttccttt aaactctctc gcatagaccg
      961 cctctgtctg gttaagagtc tgaagtgcat ccgttagctg tatctcgttt cctgctcctg
     1021 gttcttgagt ttctaatatc tcaaatattt taggagtcag tagataacgt ccgataatgg
     1081 ctaaattact tggtgctttt cccatttcag gtttttctac aaaccctttt actctgcaac
     1141 gacccttttc gctatctgtt ttaggatcaa taattccgta tttagatgtt tcattttctg
     1201 gtacacgcat gacggcaaca gcggaagctt gtgtttcttc ataatccatc atcaattgtt
     1261 gagtcaatgg gatatcatct ttcatcaaat catcccccag catgacgaca aacggttcat
     1321 ttcctataaa tgcttttgct tgaagcacgg catcccccag tcctcttgga tgagattgac
     1381 ggatgaagtg aagattgact tgagtcgttt cttcaactaa agcgagtaat tctgtttttt
     1441 ccttttcccg caaattgttt tccaattcga tatttgcatc aaagtgatct tcaatgggtc
     1501 ttttttcttt tcccgttacg atcaagatgt cttcgattcc cgaatccaat gcttcttcca
     1561 caataaactg gatcgttggt ttatccacga ttggaagcat ttcttttgcc atggcttttg
     1621 ttgccggcaa aaaacgtgtt cctagcccag cggcaggaat gactgctttt ttgaccttca
     1681 cttgctgttc ctcctaaacg acgattaact attgatcatc tatttaacga agagaaaatt
     1741 cattctccat ttttccgtca cgtaacatga tttcttttgc tgcttttttg atatcttctc
     1801 cattatacaa aacattatag attgtttgag taattggcat ctcaacacct agctgttgag
     1861 ctagctctac tgctgctttt gtcgttgcca caccctcaac gaccattccc atgttttcta
     1921 gaacttcttc cagcttatgt ccctgtccta acaagttacc ggcacgccaa ttgcgagaat
     1981 gaacacttgt acaagtaacg atcaagtccc ccacaccact caaaccgata aatgtcagag
     2041 gattggcacc catcgcgaca ccaagacggc tgatttctgc caatcctcga gtcatgattg
     2101 ctgcttttgc atcatctccg aatcctaatc catggatagc gccggcacca attgcaatga
     2161 tatttttcag tgctgcacca gtttctacgc caatcacatc attatttgta taaatcctga
     2221 aataatcatt catgaacagt ttttgtacat aggctgctgc tttttgatca atacttgcag
     2281 ctgtaattgt tgtgatatca tgtactgcca cttcctcagc atggctagga ccagataata
     2341 caacaattgc ctgtcttttt tcttctggaa tttcttcagc caaaacttct gagattcgtt
     2401 tatgcgtatc ttgttctagt cctttacttg catgtataat gattggctta gtattcattt
     2461 taccaataag ttcctgtgcg actgaacgaa tcgcttttgt tggaacaaca aataaaatag
     2521 catctgcgtt atccactgct tctgccaatt ctttatatcc gataatcgat tctgggatcg
     2581 tcaaatcagg taaaaaatgc tgatttgtat gatacttatt gatttcatca atctgttcag
     2641 gtacatttcc ccaaatacgg acatcatgcc cgttttctgc caatgtttgt gctaaagcag
     2701 tgccccaaga tccaggacca agaactgcga ttttttgttt catggatatt cctccaaata
     2761 aataattgat aatttccatt atagtataca tttcttaaag ttgggactaa tttccattgt
     2821 ttttaagtgt ttgtttactt cttttatcgt ttttacttga aataatcaat gatatgttac
     2881 aatagtctac attttatttt tacactcgtt atgctttgct tgttcctaag aggaagcagt
     2941 tttgacaatg ttactaccag cattactatt aggaggttag gaaacttctc ctagtgagta
     3001 ttgatttaaa atacataaga gacagattga acatttctaa atctgtcagg tcctgcaacg
     3061 gacagattgt ctctgttgac ggttgacata ggaacttttg ttttagtcaa cattctggat
     3121 acaaaacgct atgtaaactg gcgcaactcg ttgtacttgg acttttacta cggatccatg
     3181 caacaactaa atagtactat tgcataacaa aaaatggttg gcacccacat gtcccattaa
     3241 acagattata agttgaactg tagataatgc aaaaaatgtg ttttataacg taattgatgc
     3301 caatatttta aaaaaataaa gggagcagtt atcgctgctc tctttatttt ttatattctt
     3361 tttatccagt ctatcctaat aatcaaactg acgatagtag cggcgtatct ctaatggatg
     3421 gcagttcaac tgctccacat gagcatcgat gcgttgtgtc actacatgca tcaataagaa
     3481 agacaaaaca cgtccgcgat atttttcact gataccttct actggatagt cttttgtgtc
     3541 tatcaatgta taattgctgc aaatttttgg caaaagttta gccacacgtt cagataacac
     3601 tctctgttca tcttcgccta aaaataatgt gactggggtt gtttcttcta cgatctctaa
     3661 cgtcccgtga agaaactcgg cagcatggat agatttcgat ggaagccagc tttgttcttc
     3721 ccagtaacac atggcatatg aataaacagc tccccattga ttccctgctc caataaaata
     3781 atgcatacta tcacgtcgat gtttttctgc aaatgataag ccaaatgcat ctgctttttt
     3841 ctctgcttcc actaaccctg ttggtaaata acgttcgagc tgttcatagt attctgaata
     3901 agcttcgaat tctccattca aatacatcaa tcgatctgct gccataaaaa atttgatttg
     3961 ttctgttcca ggagctggat aagtgaccac aaaatcgcat agctgagaca acttactgtt
     4021 cgctttatcg ataaatccaa tcagtgtcgc tcctactttc ttgatttgtt ctactgcttt
     4081 cactacttct tgagttgtac cggtaacaga ggacaaaata acgatagaat cttttgttaa
     4141 tcttttgttt ccagtagtgt aatattctgc agcatgctgt acaaagacag gcaagttgct
     4201 tttcccattc atataagtga cagcttgcat cgaggaagca tacgttccac cgattcctag
     4261 ataatagaca gcgtcaaatt tttccgcata aagtttatcg atgatttctt ctacttgcgg
     4321 acgtaaagct agtgcgcctt ttattgcttt gatttgttct tcttcattga atttcagcat
     4381 gatttccacc tcttataatt tacttttcaa gactgtatca aagtcttcaa aaatcttttt
     4441 gttcaagtca atacctttag ctactgcggt tttataagcg aatagttgaa acggaacgac
     4501 aagcgctaat acagacagat attcatcaca ttctattgct aatccaagtg ttttctcgtt
     4561 tcttgctttt tttgtggtaa tggtgagagt ctctccaacg taccgactca tatatctttg
     4621 caacttttgc gaacgttcct tatttacact ttccccttca ataaagaata gcaaatgcga
     4681 agcatctgcc tccaggtatg ggccgtgcat ataagcttct aactcaaatc cttgtgacgg
     4741 aacgcggatt gtttcagtca atttcgtctc tgcttcttta gctgttcccc agtttggacc
     4801 atatccaatg gtgacgaaac gctgtgctaa acgaaataaa ctttgatatc catcaaaaaa
     4861 ttcttccgtt ttttgaataa tcgctggtaa atggttgatt attttgcgca actgttgcat
     4921 gtagtcttgt tctatttttt tgctgatttt atttttactt attccaattc ctatccctaa
     4981 gagtagtaac tgtaaaacag tcgcagaata gccttttgta acgaagccta ctgattctac
     5041 cccggcacct aaatcaataa tttgtgcagc ttctaaagca agtggacttt gcacgtcatt
     5101 tgtgatagca acaacaggta acccttgttt ttgtatcatt tttactgctt caacagtaga
     5161 agcacttttc ccgctttgtg acacagcaat cacagtatcg attgaaggag aaagttttcc
     5221 ataattgaaa aaataaaaag gttcttgaat atcgacagta agatcaccat aagattccaa
     5281 tgctggcttc gctgctaaac aagcgttata agatgaaccc gttgctaaga tcagtaaatt
     5341 cactgttttt ttcatatgtt ctcttgtcga aaaatcattc tttttcaaga tcgtacttag
     5401 tacttccttt tcttcataga tataatcttg catcgtaaac attttctctg ctcctttttt
     5461 aaaaaatccc tatccacgaa ccaaaaattc caaagaaagc tagtccgatc aagatcgtta
     5521 atggtttcac ttctttcttc aatagataaa acactatgcc aaatgctcca agacataaga
     5581 tatttggaac gatatcatca aaaatacttt gaacagtcac agcattttct cctgaaccga
     5641 tttttaaagg aatattgatg gtgatcatcg tggcagtcat tgctccaacg accatcagtc
     5701 caataataga cgcgcctaat gtcaaacttt ccatcatacc gtttgcctgg atctttttca
     5761 aaaaacccgt tcctaagcga tatccccaac ctgttgctag atagcgaaac agaatgtgcg
     5821 gaatattgaa aatcaaaatg aacaagatag ggcctaaaat atttccttgc atggctaaag
     5881 aggtacccac acctgtggca atcaatcgca aagttcccca aaagaaagaa tctcctaacc
     5941 ctgcaagagg tcccatcaaa gatgttttga tactatcgat cgcagtcaca tcaaattcag
     6001 gatcatcctt attttcttcc tccattgcag ccgtgattcc taaaatcagt gtaacgatat
     6061 gtggggtcgt gttaaaaaac tctagatgcc gtttcaaagc tgctgccatt tcttctttcg
     6121 actgatataa ctttttcaaa atcggaatca ttgcataaac ataagccata ttcatctgac
     6181 gttcataatt ccaagaaaac tccatttgaa aagaacgcca aaatacgtga tttagctctt
     6241 ttttcgttat tttgctgttt ttgatctcag aattcttcat cttcttctac ctcccctgca
     6301 gttgtttgaa gtggtagttg acggacattc ataatattga ctaccacaac tgctaaaatc
     6361 gcaccaaaaa tagctactcc ggtcacagga atctctaagt aagaagctat agcaaaacct
     6421 aagaaaaaat atggtgcaac ttgtttgttg atcagcaaac gagcaagcat cgcaaaacca
     6481 agagctggaa tcaaccctgt agctactgac aacccctttt gaacgaagtc aggaatcata
     6541 tttaatagat ttccgatcgt attgcttccc accatataag aaaccattac cacaacacca
     6601 agcatcaagg aaagaccgat accggcaagc aagtgcatat gctcgactcc tttataattt
     6661 ccttcttctg cataattgtc tgctttatgg ttcataattg gaatcaaaag ccctaagtaa
     6721 atatttttca atatcaatgt caacgtagca atcggcaaac ctagtaaaag cgcggtttct
     6781 gtaccggctc cagctgtaat agcaaaagcc gtccctaaaa tcccaccggt cacaacatca
     6841 ggtggaatcg aagcacctac tgagaacgat ccgataaatg ctaactctaa agttgcgccc
     6901 ataatgatcc cagtttttac atcacctaac acgattcctg taaacagccc cgtcacaatc
     6961 ggacgagaaa gcaacgatgt ccctagtgca tattctgatt gtgcgacaaa tgcaacaatt
     7021 cctaataaga ctgcttgtac aatcattgag gttcttcctt tcttacaaaa cttctcttac
     7081 atccactttt ttatctgctg gtacttgacg gatttctact tctatttgtt tgtcaattaa
     7141 tcgtttcaag cgttcctcct cttctggtaa aatatttacc gcttttccga tgctgcgagt
     7201 accaggtttt gccttgatcc ctcctaagtt gatggttttg atttctggat acgcttctgc
     7261 cagcttatat gcatcctcga tcgattccac tacgatgaat aacttatatt tatctgtcac
     7321 cccgcttttc aacgcggcaa tcgagtcatc aattgatttg atcactagtt tgactccttg
     7381 tggcttggct aatttgatcg ttgtctttcg tatctcattc gtaggtacat catcattagc
     7441 aatcaaaata cagtctgcgc ctattgtttg tgtccatgaa aaagctactt gtccgtgtaa
     7501 taaccgatgg tcgactcttg tcaatacaat catttttctt cctcctaaaa ttcgtcttct
     7561 tctattttct gattgagccg ctcgttacaa aactggatca ttttttttga atcagttagc
     7621 acctgctgga tcaaaacagt tgtctctact tcagcgtcca accgagatac tagctcaatc
     7681 aatagtggca aattcaatcc ggcaacgaga tagacatgat cccgattgat atattgtaag
     7741 aattcgttgt tgacacttcc gccaaaaaga tccgtcagaa caatgatttc tttatctttg
     7801 tacctcataa aaagctgcct tactgtttcc gctaaatcaa aattctcatc agtatagcaa
     7861 tcgaatacag taatagaatg atttttccca tagatcagct ctaatgaatc taatatccct
     7921 gaagcaaatt ttccatggga agctaagata atttctctat ccactttttc atctcctctt
     7981 ttcacttaca catactaaaa aagcaagttg catgccaaaa ttagtggcaa caacttgctt
     8041 atgttcaaaa ttcttcttct atcgagagaa actctgtatc ttcactcaaa atatcataga
     8101 tataggcaat ctcagaattg gggatcatga cactataatg ctcttcaatg acactaaacg
     8161 cagatttaat agcagataac ccttcttttt gacactgctt ccatttctct aatccttgat
     8221 aggtttcgat tggcatttgt cggatcaatc gttcaatgag acagctcaca tggacataca
     8281 acgctaattt tttgggattg ctgatgcttc gattcaactg cacctctaat tctctcataa
     8341 aatgatcgat ttctcccatc accttctctg tatctagaat agtcacggaa tccagtactt
     8401 tttccaatga aaaattacga atgatgcgct gattgaatat ttccttctct gaagcattca
     8461 tagtagtgtc caaccattca gctagtacag acatcttttc ccccgagatg aggtcttcta
     8521 atgaaagata gtcgatattg gtgatatcag gatctgtggt gccaatcatt cctacgactt
     8581 cgtatatgga aaataatggg tcactgtttt tcttatcttt taattgctga tattcatatg
     8641 ggatgatttt caactgacaa gccgtaggta agcttttttc tagcagttca cttaagtgga
     8701 ccgccgtacc gattccagtg aagcaagtag taatgagtgc tttgggtttg ttttcctctg
     8761 gatagagcag tcgccattct ggctggatct gtcgaacagt ctcttctgct atctcttcta
     8821 atgatacatt tttttgcagg cattccccta ctgtgattgc taaaggtgtc gtcacattat
     8881 tcaaaatcaa aagcggtacg gataactgtt ttttaaaaaa ctgatggatt tctttcagag
     8941 atcccatgtc tactaatatg atcaatccat ttgaaacatc gctgttttcg caataatcaa
     9001 ggatttctga agcaatctgc tgtggtgtga catctagtgg catatcaaat gattcaaata
     9061 gatcctcttg taataaacga tttactacat ttgccatact gctagcagtt gcataaccgt
     9121 gagcagcaat catcgctttt ggcagtcgtt tttcttttga ccatttcgct ttttttagat
     9181 agatcgtcag taaaatccga tccatacttg tgtcttcaat atctaatttg atcttactta
     9241 attccagaat tcgttggaca tagtgataac tagatggata agactgagaa acttgttgtt
     9301 ctaattcttt gattagttgg ataatatcat gttcttccgg taaccatttg atagtgcttc
     9361 gctgatagag atagtaactc aaggcataga cactgtttcc atcgaatttg atttgatagg
     9421 cagtttccat ttgtcgaaag gtctctcgga tagattgtgt ccaataaacc agcagctcgt
     9481 gtttttcttg tctactggtc tcaaacagca aaaaatcaaa taattgaatc acttcttgct
     9541 ttaattttcc ttcgcaagaa tatagcagac agttattttt cttgaaatca attaggattt
     9601 gctcaaaact tttaacgatt cgctgctgtt cgggctgttg cttctccatt aattgctcta
     9661 aggtctggtc ttgcgtaata tagattcctt gctgtgctgt atttttagta ataggctgcg
     9721 caagtagttc tttttgcaaa tgatggatcg tgacatggat ttcaggctgt tcacgctgtt
     9781 cagcatatgc ttttgctgct gaaactttga cgatattttt cagctctcct atgtttccgg
     9841 ataatttctg acttgttaaa agtgacaaag ctggtccact gactgacaaa gggctcccca
     9901 tttttctttg ttcttcgaga aaaaaagagt aaatcagttc tagccgttca ttacgactac
     9961 gctgattaag tgcaggtagt tcgattcgga taggtattct tcgaatgaaa gttgttaaga
    10021 aatgactagt aatctcttca gtcgtagcaa aaaagagacg tgttttgatc cggcgtgaca
    10081 aattaggttc tcccatacga taaatcacac cttgatcaag ataggtgaac agtttttcct
    10141 gaccttctgg tgttaagcga tgtacctcgt ctaaaaacaa gatcccacca tctgctgctt
    10201 caaaagcccc ttttttattt tcttctgcac cagtgtacgc tcccttaaca tgtccaaaca
    10261 aattgctagt caaaagttca ggattatctg catattgtgc acaattaaaa gtgatgaatg
    10321 gtgcagaatc ttctagcaga tcatgaagca gacaatactg atagaccaaa ttaactaaat
    10381 aacttttacc tgtgccactt tcgcctgtaa tcaaaagtgg taatccgcca tctggatagt
    10441 aaagagctgt tttgatttgt tcgatacttt ctttcaaact ggcgtcgtat ccgatcataa
    10501 aagagaataa gtcttttggt tgcgcgaaaa aaggctgttc ctctttgaga tcatcgatag
    10561 aaaaataaaa attcgtgcgt aacttaaaaa attgtttttc aaaagcttct ttgtggaaat
    10621 aaatcactgg tcgagaattg attttgacta gtagttgctc atcatttaac tggttcaaat
    10681 aatgactgac tgtgtttctt tttaccccaa aatgatcagc taacctttgt gctgtaaaga
    10741 cctcgttcat atgttctaaa tcgaaaaagg ctgtctggtt ctctaagtaa cataaaattt
    10801 ccttcttcaa caacttattc acccctcctc catcatagaa aacggattca ttttgtcaat
    10861 aaaatcttta ataaagaatt gaaaaatata tcttattata gacagcagcc tacttatccc
    10921 ttataatttt tattctaaaa aacgtacagt tccttccagt ttttatactg gaatttcaac
    10981 atatgaaaga ataaggaggc tatgactatt caatgaaatc ggataaatat aaaaacagga
    11041 aacatacttc ctggaaaact tttcgagaaa tcatcggatc ttatctcgct gtagttgtat
    11101 ttttgccttt gctttatatg gctatgacag aacaaactcg ttttattggc gtagatacgc
    11161 aatatatagc cgaaacagga tttttattca tctttatctt gatttttgcg ttctataaat
    11221 ccttccatac aaaataagat tcacagattt caactttcct gtctgttttt agctattaca
    11281 aatccttata tgtggtataa caacaattta ttggcataat gaggaaaaac gagttatgat
    11341 gctttcagag agtaaagagg tactgttgtc accatccttt ttattgatta cgtacaccac
    11401 tcttagtttt ttcccattga ttacgaaaac aaggtagaaa cattgatgtt cctaccttgt
    11461 tttctttttt tattttcaga tcaaaatctc aagtggcttt tgacttgatg tcgggaggtt
    11521 gtcttcgttc catcaaacct gatagaatct gcgccaaacc atagttttct ccactattat
    11581 ttattcctct aagatagtac ccacaataaa cgaataaata tttttctcat tttcatactc
    11641 cttctttgaa aatcaattag atttctctca acccactttt ttacaaaaat tacgtagcaa
    11701 aaaagattgc aagaacaaat taaaaaagaa gtaaatagag tttcatctat aaacatttac
    11761 ttgatatatt ttttatgcag aattcattta tagaaaaatt aagtaaaata gacgttccta
    11821 tgaatgaaga gactggcatg ttttctcatt ttcttttttt taaaaaaaat agtctattca
    11881 atttctaaag cttcttcata ataaaacttt catttatgaa aaggcttgtt ctcttttcat
    11941 tctaaatttc ctaagctaca atgtggtagt acttgttttt tcaattgtgg acaaataaat
    12001 aataggagga atcatatgat tcagttatta cgttatgcaa aagactatcg taagcaaatc
    12061 attttgggcc cgttcttcaa atttcttgaa gctgtcttcg aacttgtcct gcctttaatg
    12121 atggcttcct tgatcgataa tggactaaaa atgaatgacc gaggaaaaat cattgaaatg
    12181 ggcttatgga tggtcgctat gtctgtgatt ggtctgattt gtgctatcat ttgccaatac
    12241 tatgcttcag tagcttcaca aggatttggt acagagttac gtaatcagct aatcaaaaaa
    12301 atcaatactt tctctcacaa cgagttgaat cattttggaa cagatacctt gatcacccga
    12361 atgacaaacg acatcaatca gcttcagcta gctttagcaa tggtcattcg tttattgatc
    12421 agagcaccgt ttttaagtat cgggtcagtg gtcatggctt ttgtgatcga ctgggaagta
    12481 ggtctgtttt tcttagcatt attgcctatt ttctcaatca ttttattttt tatcatcaaa
    12541 aaaaccgttc ctctctacca aaaagtgcaa gaaaaactag atcagctcaa tgaacacgtt
    12601 agtcagaatc ttagcggtgt tcgtgtcatc cgcgcatttg cgcagacaaa aaaagaaaca
    12661 gagaagttcg ataaaagcac aaatgatcta gcgaacaatt atttacgtgt ttccaatatc
    12721 tctgccctat tatcacctgc tacaaccttg atcatgaatg tcgggatcat ctgtttgctg
    12781 acagttggcg ggatcaaagt aaatattggt agcttgcaac aaggacaagt tcttgctttg
    12841 atcaattata tgaatcaaat gcttttggca ctgatcgttg tttcaaacct cgtcgtgatc
    12901 ttcacacgtg ccgaagcttc aggaaatcgg gtgaaagagg tgctagacac agaaaattcg
    12961 attcttgaag ctgaggtcag tactactccc gatttttctt ctgaagcaat tatcgctttt
    13021 gaccatgttg acttccgtta tactcctgat tctggtcttt ctctccaaaa tattacattt
    13081 cagctgaagc gaaatacagt ccttggaatc attggtccaa ccggaagcgg gaaaacgact
    13141 ttgacacaat tgattccgcg tttctatgat gtcagttccg gtacagttat aatggacgga
    13201 atggatgttc gttcttggca gctggatcat ctccgtcagc aaattgctct tgttccccaa
    13261 acttctgtac tatttaccgg gactattcgt gaaaaccttc aatggggtaa gaaagacgcc
    13321 acagaaaaag aatgttggga agctctgaaa atcgctcagg cagaagaatt tgtccgtcag
    13381 cttccaaatg gtttagatac aaaagtcatg gaaaatggga aaaatttctc tggcggacaa
    13441 aaacagcgac tgacgattgc aagagctttg attgccaagc cagcattact gattttagat
    13501 gactctttaa gtgcgttgga ttatcaaaca gacttggatt tgcgtaaggc gctacagact
    13561 tatcttggca gtacagtgat tattatctcc caacgtgtcc gctctattca agaagcacat
    13621 catatcttag tgatggatca aggtaagatt gctgctcagg gtacccatga agaattactt
    13681 gctcaatcag cagaatatca ggaaatcgtc gcatcacagg aggaagaata gttatgaaag
    13741 taaaaaaatt atccttgcag acgctccgcc gattcattcc ttaccttact gcctatgcaa
    13801 aagacatttg gctagctgtg atactaggaa tcatcaatgg gattgcaaca gttgtgatga
    13861 cgttacaaat tggtcaaagt atcgatcaaa tgattggaga aggacaggtc cgcttcaatc
    13921 gactgttcca tttacttatt ctattcggtg gtatcgtttt aatcaacgta gtcagtcaat
    13981 ggctcatcca agtgttaagc aatcggttag cttacttatc cgttgcaaaa ttaagaaaag
    14041 atgcatttgc tcatctgaat cgattgccac ttcgttatta tgatcaaaac tcccacggaa
    14101 atatcgtcag tcgatttaca aatgatatgg acaatatttc cattgcaatt tctgcggcct
    14161 tcaatcaatt attttctgga gtggcaatca tcattctttc gtttattttt atgatgcgtc
    14221 taagtccact tctgacattg gtcgttcttt gttctacacc aattattttc cttgtgagtt
    14281 ggatcgttgc tcgtgcttca caaacaaatt tcgatagaca gcaaaggatt attggggata
    14341 tctcgggctt tgtgaccgaa cgaatcggta accagaaaat cgtgaaagct tttcagcaag
    14401 aagaagctag tcaacagcaa tttgaactgc taaatgctga tctatatgaa aaaggacaac
    14461 gggcacaatt ttcttcttcc ttgacaaacc cgtcttctcg ttttgtagat caccttgctt
    14521 atttatcgat tggtttagtt ggcggcctat tggcattgaa gagtggttcg tcaatcactg
    14581 ttggtgtgat ttccagcttt acgatctact caagtcagtt ttctaaacca tttatcgaac
    14641 tttctggaat cacgacacaa ctgcaaaccg ctttttctgg tctagaacga gcatttgatt
    14701 tgatcgatca gccagaagaa aagcctgatt tgccagatgc ctatgccttg gaacccaaaa
    14761 atatcaaagg aaaagtctct tttgatcatg tttctttttc ttatgacccc aagcagcgtt
    14821 tgatcgaaga tttcaatttt actgcttatc caggtcaaac cattgctata gtaggaaaaa
    14881 caggggccgg aaaatccaca cttgttaatt tgctgatgcg tttttatgac acaacaaaag
    14941 gaacaattac agtcgatgac catgacatcc gctctatcca acgtgataca ttacgtaaaa
    15001 gttttggaat ggtgttacaa gatacttggc tatttgacag tacattgcga gaaaatcttc
    15061 gttttgggaa tccggaagca agtgacgcag aaatcaatga tgccctaaaa gcctcttata
    15121 tgtatgaatt tgtagaacgt ttgccggaaa aattagatac taagattggc ggtcaagggt
    15181 taaagatatc agatggacaa cgccaactgt tgacgattgc tcgaacgatg atcagtaatc
    15241 cccctatgtt gatcttagat gaagctacca gctcagtcga tacattgaca gagaaaaaaa
    15301 tccaacaagc cttcttagca atgatggaag gaaaaaccag ttttgtgatt gcccatcgcc
    15361 tgtccacaat caaaaatgcg gaccagatat tagtgatgga tcagggagct attgtcgaaa
    15421 tgggcaccca tgatgagctg cttcaaaaag atggttatta ccgacggctc tatcaagcac
    15481 aattcacagc acaataaaaa caagcagtct tctgggatgg gaagactgct tgttttttat
    15541 ttagcgtgga tcgctaaact tcttaaaatt tt
//
LOCUS       DADVXK010000066        15409 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.067, whole genome shotgun sequence.
ACCESSION   DADVXK010000066 DADVXK010000000
VERSION     DADVXK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.067"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            693..788
                     /locus_tag="KB909_001926"
     CDS             693..788
                     /locus_tag="KB909_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6837944.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1090..1335)
                     /locus_tag="KB909_001927"
     CDS             complement(1090..1335)
                     /locus_tag="KB909_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837945.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1680..1964
                     /locus_tag="KB909_001928"
     CDS             1680..1964
                     /locus_tag="KB909_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837946.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1967..2383
                     /locus_tag="KB909_001929"
     CDS             1967..2383
                     /locus_tag="KB909_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837947.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            2754..3434
                     /locus_tag="KB909_001930"
     CDS             2754..3434
                     /locus_tag="KB909_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBB6837948.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPD"
     gene            complement(4049..5089)
                     /locus_tag="KB909_001931"
     CDS             complement(4049..5089)
                     /locus_tag="KB909_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6837949.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(5438..5764)
                     /locus_tag="KB909_001932"
     CDS             complement(5438..5764)
                     /locus_tag="KB909_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837950.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(5751..6554)
                     /locus_tag="KB909_001933"
     CDS             complement(5751..6554)
                     /locus_tag="KB909_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6837951.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(6907..7197)
                     /locus_tag="KB909_001934"
     CDS             complement(6907..7197)
                     /locus_tag="KB909_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6837952.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(7333..7512)
                     /locus_tag="KB909_001935"
     CDS             complement(7333..7512)
                     /locus_tag="KB909_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837953.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(7509..7859)
                     /locus_tag="KB909_001936"
     CDS             complement(7509..7859)
                     /locus_tag="KB909_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837954.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(7852..9177)
                     /locus_tag="KB909_001937"
     CDS             complement(7852..9177)
                     /locus_tag="KB909_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6837955.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            9627..10241
                     /locus_tag="KB909_001938"
     CDS             9627..10241
                     /locus_tag="KB909_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6837956.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(10406..10648)
                     /locus_tag="KB909_001939"
                     /pseudo
     CDS             complement(10406..10648)
                     /locus_tag="KB909_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10852..12171)
                     /locus_tag="KB909_001940"
     CDS             complement(10852..12171)
                     /locus_tag="KB909_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBB6837957.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(12326..12913)
                     /locus_tag="KB909_001941"
                     /pseudo
     CDS             complement(12326..12913)
                     /locus_tag="KB909_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13551..13808)
                     /locus_tag="KB909_001942"
     CDS             complement(13551..13808)
                     /locus_tag="KB909_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6837958.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(13801..14070)
                     /locus_tag="KB909_001943"
     CDS             complement(13801..14070)
                     /locus_tag="KB909_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6837959.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(14201..14380)
                     /locus_tag="KB909_001944"
     CDS             complement(14201..14380)
                     /locus_tag="KB909_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837960.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(14761..15327)
                     /locus_tag="KB909_001945"
                     /pseudo
     CDS             complement(14761..15327)
                     /locus_tag="KB909_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4807 a         2804 c         2399 g         5399 t
ORIGIN      
        1 ttccgttttt tcatccattc ctttcttccc cccttacaaa taaataataa cctttaacaa
       61 ccaactcgta aataggttgg ttgttattat acaaaaggat attagtactc agataaaaag
      121 ttgttagtac tcagataaaa agttgttagt actcagataa aaagttgtta gtactcagat
      181 aaaaagttgt tagtactcag ataaaaagtt gttagtaccc ttctgtatcc gttgggagag
      241 taaggctcaa ctgcccccta aaaagggttc taaaaaatct ttaaaaaata aataaaataa
      301 acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc cactttttaa aataaacagg
      361 ttcgcgcatg atattaaact gccaatctag ctccctatgg tcgctgtaag aaggagtgat
      421 cgctacgctc tcacatttta cttgcagcag tcgcctttag gctccttcgc caaaaataat
      481 tcattaggga ctcctttgtg gcgtcctgag agctcgtcta agccgttcta agacaagatt
      541 cgataaaaac tatgtccttc gttctaaagc gccttacagg cggtcagggc aagccctaac
      601 aaccccaagg caataaaaaa cttaggctta tttttgcttt tttattgtat aattgattgt
      661 cgcctatccg acagtcttgc gactggaagg aggtgtgttt cgtgttcact aactttattt
      721 gctcccttct tgttgggctt ttaagcgctt tgttcagtta ctggttgaat aaccgaaaca
      781 agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa agccccagag aatccgacct
      841 ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa tcaaattata acagaaataa
      901 atatttattt caaaaatatc ctacaaaagt ctaaaatccg taattatttc ttatatgcaa
      961 catttacaaa taaagtcgct ctgagagctc gtatttttcg atttaagacg ttttatttag
     1021 tttttggtgt atttcattgg tccaagctaa aaaactctta gaagcgattt tagagccatt
     1081 taaacccact taattatatt ctccatgaaa ttcgctccat gcgtcaaaag ctgcgtctga
     1141 aattccgccg tcttcgttca ctagttgcat taatttttcc aacgatcgtt ttctttcggg
     1201 tgtcatattt ttatattcca acaatttttc gtctgttaaa tcgaacttga ttgcttgaat
     1261 tgcttgctct aatttttcta agttttgaaa atattcgtaa ggaaattttt ccattttttc
     1321 tttctccagt ctcacaattt ttctagaaat aaaatcactt ctttgccgtc tatactctca
     1381 aaaaaaatgt cgtttgaaaa actaaataaa tttttgatcg tgcattttta aatttggtta
     1441 tcgattacac gtgcagcact cccccccgaa ttttaaagag cataaggaaa cgtgtaccca
     1501 ctttctaaaa aaagtgggta gataggctgt gcctatcacg tttctcagaa aaaaatttga
     1561 tatcactttt tcgccatcgt gggtagctta tgtatagcat tttggcaaaa aacagctata
     1621 caaatatagt atttgtatgg tatacataaa ttatacataa ttgcaaaagg agatttttta
     1681 tggacatttt agttcggaat attgatccaa agtttgttgc aacaatagac aaacgttgcc
     1741 aagaactcac gaataaaaca ggagaaaaat ggagtcgaaa taaatatcta aaagttttaa
     1801 tcgaaagtga ttttgaccgt caacttacga cttacaaaaa agaccaattc gatttattgc
     1861 tcgataaatt tattgctatc caaacagaaa atactcaaat attaagcgag tatgtctaca
     1921 caaataatca aatcattgaa atgcttatcg gaggaatgat ataaccatga gaaaaacttc
     1981 tgtccaaaaa catgttactt tgtaccctag tcatgttgac gttttagatt ccatcatcga
     2041 aaaaaatcca gatatcaata actactcgga agccattcgc tttttatgta tgagttatga
     2101 acccgatacc aacacgacca ctaccagcaa tcaggcaaaa ctaaatgcta tgggaaaaga
     2161 aatttccatc atgactgaaa tcatcgcaga atttgctgat ttatatctaa aagatacagg
     2221 cgttcttatt ggcacaaatt ctaaagtata tcaagaagtg aaagaaaaaa tcgaagctaa
     2281 actaaatcca tcaaatcgaa atcgaccaaa gaatcatcaa aaagaaacca gtcaaacagt
     2341 cacttctaga aatttcgacc caacaaattt tctaaaacga taaaaaacag ataggagtta
     2401 ttcctatctg ttttttattt agaagcccca tacaatatgc tagaatgtac tagcaatctt
     2461 agtcggttgt aagggacttg tctacttgct taatgtaagg ggggcgagtt cttttttatt
     2521 tattcttcta accagttacg cagagaaatc tttggcaaat ctgacgttag gcttgaaaaa
     2581 gtaaattcta atttggcgat tttattgccc ttttttgctt ttatttttgt gactttaaga
     2641 tcattgaagt atttttttag ttctcgtaat gcaggatttg gttctgttgc aaagttttaa
     2701 atctactatc aaataaggta gaataataga aaaagatagc aggaggaatg acgatgaatc
     2761 attttaaagg aaagcaattt cagcaggatg tgattattgt agccgtgggc tactatcttc
     2821 gttataacct tagctatcgt gaagttcaag aaatcttata tgatcgtggc attaacgttt
     2881 ctcatacgac gatttatcgt tgggtgcaag aatatggcaa actactctat caaatttgga
     2941 aaaagaaaaa taaaaaatcc ttttattcct ggaaaatgga tgaaacgtac atcaaaatta
     3001 aaggaaaatg gcattatttg tatcgagcca tcgatgcaga tggtttaacc ttggatattt
     3061 ggttacgtaa aaaacgggac acacaagcag cctatgcttt tcttaagcgg ttagtgaagc
     3121 agtttgatga accgaaggtt gtagtcacag ataaagcacc atcaattgct agtgccttta
     3181 agaaactaaa agaatacgga ttttatcaag ggacagaaca tcgtaccatt aaatacctga
     3241 ataatttgat tgaacaagac catcgtccag taaagagacg caataaattc tatcgaagtt
     3301 tacgcactgc ctcacccacg attaaaggca tggaagccat ccgaggatta tataagaaaa
     3361 cccgaaaaga aggcactctc ttcgggtttt cggtctgtac tgaaatcaag gtattattgg
     3421 gaatcccaga ttaaatcata gataccgtaa gggattttat tctttattta aaactttgca
     3481 acagaaccgt ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc
     3541 ttaatgcttt cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc
     3601 tttctttttt tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc
     3661 aattcatcac aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt
     3721 gtaattgaat attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg
     3781 aaataagtga attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac
     3841 actagttccc tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa
     3901 aacctacgtt tgcgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta
     3961 tttatttgta acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat
     4021 catttttata gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg
     4081 gtaattcgtt aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga
     4141 caaaccaatt ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt
     4201 tttgtttttg ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat
     4261 aagattccag ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg
     4321 cattatgaat agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta
     4381 tcaagtttaa tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga
     4441 cgaagttatc tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc
     4501 tattagtgtc tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg
     4561 agtccttgat atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat
     4621 tgatttctcg cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt
     4681 cttcctcttc catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca
     4741 ataaattagg catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt
     4801 tcagaagacc tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt
     4861 gtaacaattt cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta
     4921 cccagttatt tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg
     4981 catcatttga tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat
     5041 atttttcacg ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc
     5101 tttctgtagg atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta
     5161 tccactatat atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt
     5221 ttttatcttt ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg
     5281 tttaagctca tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat
     5341 attacaatat gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa
     5401 tatcacgata ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg
     5461 ctagtttata tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta
     5521 taacgtctgg tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca
     5581 ttagaattgg atttatacga atgctatctg ctgttcttac actacttcct tgatctttta
     5641 tgactttact tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat
     5701 tctttttatt tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg
     5761 ccatcaaaat caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca
     5821 gctgttgagg gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg
     5881 gttattgtcc tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg
     5941 gttgctgcag acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga
     6001 actcctcgta cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt
     6061 aactttatta gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca
     6121 gaaacagtaa atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata
     6181 taatcatagt tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact
     6241 tgagtaaatt ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct
     6301 ttatagtcca gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta
     6361 ggttggtttg ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca
     6421 atgtccacta aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg
     6481 ctagtcgtag ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt
     6541 aaaatatccc ccattcatct tatattataa tataattata tcataatatt gtgatattgc
     6601 aatatcgtat atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat
     6661 cggttcggat ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta
     6721 ctttaaaatt ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt
     6781 aaacattact aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt
     6841 agaaaaaaac aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga
     6901 ttgatattat atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc
     6961 tttttctaaa gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct
     7021 taaatcataa acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct
     7081 tgcaaccgtt ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa
     7141 attcttgata atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt
     7201 gcgtaagcct actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt
     7261 ctagtatcta ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat
     7321 ccgtaaaata ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc
     7381 tgcagcttct acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc
     7441 ataaccccaa atctcttctg atagctgatc aaaggttata tactttagct catattgctg
     7501 gataatgttc attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt
     7561 tcgtcgtagt gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc
     7621 ttgccaatga tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat
     7681 actgatctat tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt
     7741 tgttcttttg ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta
     7801 tgatcagata aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt
     7861 tttaattccc ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct
     7921 agcgccttct aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat
     7981 cttgtcaata attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa
     8041 atccagctga agcgaatcgg tgtacacaag cttgctatag gttattccaa catgccttac
     8101 ttcttgtcct tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt
     8161 attatctgtg atagggatct tcatctggtg tgaaaaccct ggtctcgttt ctaagatcga
     8221 cgtgccaatg tgtaaatgga cacaacctgt tttacagtta tgctgcctaa tgcgtatcgc
     8281 tacttgttcc gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg
     8341 tggtaacact tgtgaatttc catatgattt ttcctttgtc ggttctggtg ggattgctat
     8401 atctgttcga tcgatcccat tagcatggaa gtacagctgt aagccaatca cacctagtct
     8461 attcttaatc gtataaggat tccagttagc aagatctcta atgctcataa tccccatctg
     8521 attgagtctt tttttcattc gagagccaat tccccaaaag tccgtcattt caggaatatt
     8581 ccatactttt tcaggaacgt tttcgtacgt ccattccgca acaaatcctt cattatgctt
     8641 tgcttcgttg tctaaggcta gtttagccaa aaggggatta tctccgacac ctactgtagc
     8701 aatcaatcct agctcttctt taatattctc ctggatcatt tgagccagct tctttctccg
     8761 ttgacttcgt gttccttcag tcgtaaaaag attcagtgat cgggtcactt ttaagattga
     8821 ttcatcgatc gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt
     8881 tacctgcata tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt
     8941 aggaaatggt tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt
     9001 tgcttcagga gaagaagcta atatcaatcc tgaaccagta ttatcagctc gactcataac
     9061 aacaagttct gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa
     9121 gcttttcata tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa
     9181 taacactcca ttctttcaca ttatacaaac atatgttcga tattgtaaag aagaaatagc
     9241 taaatacata aaaaaagaag cataggtatg ctatcaccct gcttcttctt ttgatttgta
     9301 tgatcaattt attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc
     9361 taaaagagtg agagactgca aattagagta cggacttttt tggagttccg ttctttaata
     9421 ttaacaaatg aataaaatcc ttacaacatt tgagaataag ttatcagtag acacttacaa
     9481 aaaattctca tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat
     9541 agacactggt ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa
     9601 atagttgcag aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg
     9661 atcaaaatga acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca
     9721 tcgagaaaca atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt
     9781 acgtccgaga tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg
     9841 acgagatcat cgcttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta
     9901 gtttaccgat catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc
     9961 tgatcatcca aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc
    10021 aggcacaagg aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat
    10081 acagtgcaga cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc
    10141 ttaaaaatgg tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg
    10201 tgtatagaat aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat
    10261 tatcttctca tctttaattt cctacatata attactatct ataaaattaa gtcttactca
    10321 gaacagataa agcataaaat tccaacaaac cattttttac ttaactaaat aaagagtctg
    10381 ttaatataat cttcacttat ttacgttaat cccctactgt atttgttggt tccttatcta
    10441 tattttctac aaaatcctta ttatcttgtg atttagcttc gtataattct ttgtatgtcg
    10501 acacattggt tatactaatt cctatagcta gttcttgaga ctctactttt ctctctagct
    10561 cctttgacaa agtgatttga gatttatttg gttccgttgg agtcaattct atagattctt
    10621 cataaaaatc tctatacata aagctatccc tgaataattc atagctttaa ttctttggca
    10681 cattttattg aaatatgtat cactaatatc cctatcaact gattttgact aaaaagttac
    10741 ttcaaacatt cactgttcaa aaatattgag gaataaattt tgggtgtaag gcattttgag
    10801 catacttctc cctggataac ttcccagtaa aaaaatcgtt agattgttgg attagatcca
    10861 ttgactggct cgcctcaggc gagcaaagac cctgtagaat tcattctgat acacatgata
    10921 actagataat ttgagataga ctcgtctacc cgtttggact aatttcccag caactttcag
    10981 aaacttcaat cgaatagaat gaatggtcat tcccttttgg acttcttcaa agccaatcgt
    11041 tcttaagaag ttgactaagt tgtaagctat caagctgagc atcattcgga catgattctc
    11101 caaaaagcga ggactgtctg ttttgtcaaa gtaaaagcca gctttcgctt ctttaatgaa
    11161 gttctccatt gtgccacgtt tggcatagat agaaaagatg gtatcaggag aaacattttc
    11221 tgatagattc gtcacgataa attcatgtcg aaagagtagt tcgcccgctt cacgtgttga
    11281 gcgtatacac acgcgacgac tttgtgacca ggattgtgct tgataagtgg tcgagaagta
    11341 ctgaacttct cgttcttccc acttttgatt atcgccataa agtactgatt tctcagctat
    11401 ttgacctagt ctacgattat tcttcagtcg aataacataa tgactctttt ttgattcaca
    11461 cgaatcatac acaccaggtg tagcgaaccc gctgtctcca cgaaccaaga tgtcagtgtt
    11521 tggtagagag tgattatagt gctctaataa aggtgtgaga aactccttta cgccttttga
    11581 tgtatattga tttcctgaac gtagttcagc ttttaagaag tcaccagtca atccgtcaaa
    11641 agctaccaat ggatggtaac cataggtttg gtagtgtgta ttataattcg tttgttcttg
    11701 gtgaccaaat gtatctgaat gggtcgaatc taaatcaatg attaattccg tatcattacg
    11761 gatgaggcgt gctttatcga taagttcttg gttcaaagct tgaagttcat ggatattctc
    11821 ctcagatagt cgatctaaaa atcgggaaag tgaagattga gaagcgagtt ctttcctatc
    11881 taaaacagct ttaaacacag gatcttgtct caggagatta gctgcagaat cagctgagta
    11941 accagcaatt aattgcataa tgaactgctc aagtatggat aagttgtcat gagtaaaata
    12001 cgctcgttcg tcttcaatgt gaatgtgttg cttagccagt tcagaaaaac caaagatgtt
    12061 catcagctct ttcactagga cgagacccga atcactcgat aattgaccac ctgtatgaga
    12121 aatagtgata tttgaattga attttacttg gtttttgtgt aagctagtca tgaaaagaac
    12181 tcctttcttt tggttggttt agtcacttta accatagcag aaaggggttc ttttttcatc
    12241 acttaacggg tgaagatgaa aaagtaattg taagctgccg tgaggcagtt tcacatggtt
    12301 ttaattaaaa gtatgaatta ttcaggctat cattaatttt ataaaaaaaa ttaaatgttt
    12361 ttagcactgc catataacat tcaaaacatt cttctatagt tggtttactt ccttgaggag
    12421 aatgaaccaa tttattacgt ttttctatga aatttttaat ttcctttctt atttctttcg
    12481 gaaactcaat attaaagtac cctttaaaca tgctccctaa taatttgtct acagggggag
    12541 attgtaaatt ctcaaatatt agagttaaat caggtttctc ttgttgataa aattccttta
    12601 cccctatttc acaggctgta attatcgaaa taaacctatc tctagtattt gatatatttt
    12661 tacttctttt aaggagtata agagaaaagg ggatactttc gtgtccatgc atgtaattaa
    12721 ctaattgttg agcttcagaa gttatatctc taattatata gttaacggaa ttaggaagtg
    12781 tctttaactc taatgaaatt tctatccaat tactatcttc taatctgtat atgctcgaag
    12841 tataatttga ttcgtcagca agcatcgcta catcccaaac actgatcata aaatctttta
    12901 aacgttcaat catttcagca atattgctaa aatcagctaa tttttcttta gaataaaaaa
    12961 aaacatttat atcagaatca ataaattcta tttttttatt actatatcgt catcattatc
    13021 ttgaccattt atgtttattg ttccctgagt ggggagtact tctttcaaat tcaagttaaa
    13081 tttatattcc attacttctc ctccaatata taaaaattac ttaactgtat ccaaatttaa
    13141 tatgtaaata aatcattaat ttttagctaa attctatgag aagtttattt ttgttgtttt
    13201 tgctaattaa ctaaaactag tacaaaaaat ttaaaataga ttattaaacc tattgcttat
    13261 tctattcagt catatatata agcgtcatcc tttagtaact aacatcccac actacaatag
    13321 tattataaca tatctattca acttcaaatt gttgaaattt aagccattta tatttacttt
    13381 tcctcaactt tagaaatgat tttactaacc ttatatccgt aatacgcgta acaaacacat
    13441 tcattaataa caatcaacac taagctatat tagcttttta aatgactagg gtaaataaaa
    13501 taaggatcaa aaacttttaa gtttctgacc ctttccttac ttccgattgg ttaatagtga
    13561 tcttttgcag aataaataaa tatcgtttca ttttcaactc tatatatcag tctatgttca
    13621 tctgtaattc ttctggacca ttttccagat aaatcatgct ttaatggctc aggttttcct
    13681 aatccagcaa agggggaacg atcgatatct tttattaact tgttaatctt ttttatattg
    13741 cttttgtttc cttgctcatg ccaataaaga taatcatccc aagcatcatc agaccaagcc
    13801 ttaatcatca gattcaacct cgattaagtc atgtgtttta aatgcacctt tggagaattg
    13861 ttcatctcct cgacgaattt tttccatgac gtaattatta gaaagtgttc tcaacgtttc
    13921 ttgcatagaa tcataatctc tttttgataa tacaacaact gtatcttcta catctttact
    13981 tgttacaata agtgtttcag catcctcatt aacttgtttc atataactac gtaaattttg
    14041 gcggaaattt gaataagcta ctgcttccat tcctttcacc ccttatttat ttctataaaa
    14101 caattgtaca ttatattgta caattaagca aatgattaat attctaactt cttataatta
    14161 aaagtgctat cacttttagt ttttaggata aaaagtgacg tcactttttg agtgctggta
    14221 cctcaaatcc tgctttttct tgggcaatca ataaatctaa cgcaatacac ataatcctgg
    14281 attcactttt gccgtacttc tgctttagtt gctgcaattc tttttgtctc ttttcatcca
    14341 acgtaacggg taaccgttta tttcctattg caattggcat tagtactctc tcctttcatc
    14401 gaaataaccc tatgaaaaat atggctgcaa tcatcttgaa tagtagactc acaagggcta
    14461 atacaaagcg ccaaaagatc aaacaaaata ccagtattgc caaaaatact acgaagttta
    14521 aatgcacagc tgcagcatgg cgcataagta tttcgccaac aaataggact aacaatagag
    14581 gaatgatttt attcatatgg atctccttct ttctcttagg ttatcgggtg ttgcccgctt
    14641 atttcgcacc acctaagcgg cgggggcggt tggagcgatt ggtgcgaaat aagaaccatt
    14701 cccttagtta ctaggttttt tgtccttatt tcacacattc tcacttttcg gtataaatga
    14761 ttattgcctt tttttccttt caaatcgttg atatggcatt cgtttacggt caagttcatt
    14821 ttggatttct tctgtatcgt cgtaagtata ggtgtctaaa aaatcagtta aagtcgtgta
    14881 ccagtcgtcg cctgggttat ctacttcttc tacatattcc ctcaaaaatg cttcgggtac
    14941 agcgagttca taatccattc ccattaacac gatagattcc gttccacacg tcaaaaatct
    15001 agtaaataca aggtaataat cgtctatcgt cgcatctttg ctgtttagct cttccatttc
    15061 ttcttccatt aattccatgc tctcaaaaat tgaataatat tctgattctg agtaatagtg
    15121 tttcctgcaa atcgtgtagc tgacaaagtt ttcgaccagc tcactccttt ctaggtaaac
    15181 attcatgatg tatttttctg tttctagtcg tagaagctcc gttccttttt ttaccgtttc
    15241 aggacgacgt ttatacacgt ctaaacgatt atggctgact gtgaccttcg tttgactcgt
    15301 ttcactttcc aaatacaatt gttcttcggg ttctgttgca aagttttaaa tctactatca
    15361 aataaggtag aataatagaa aaagatagca ggaggaatga cgatgaatc
//
LOCUS       DADVXK010000067        15334 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.068, whole genome shotgun sequence.
ACCESSION   DADVXK010000067 DADVXK010000000
VERSION     DADVXK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.068"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            72..2132
                     /locus_tag="KB909_001946"
     CDS             72..2132
                     /locus_tag="KB909_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBB6837961.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2215..2784
                     /locus_tag="KB909_001947"
     CDS             2215..2784
                     /locus_tag="KB909_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6837962.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(2959..3765)
                     /locus_tag="KB909_001948"
     CDS             complement(2959..3765)
                     /locus_tag="KB909_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837963.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3903..5417
                     /locus_tag="KB909_001949"
     CDS             3903..5417
                     /locus_tag="KB909_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBB6837964.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5820..6803)
                     /locus_tag="KB909_001950"
     CDS             complement(5820..6803)
                     /locus_tag="KB909_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBB6837965.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6808..7455)
                     /locus_tag="KB909_001951"
     CDS             complement(6808..7455)
                     /locus_tag="KB909_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6837966.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7540..8172)
                     /locus_tag="KB909_001952"
     CDS             complement(7540..8172)
                     /locus_tag="KB909_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6837967.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8188..8739)
                     /gene="coaC"
                     /locus_tag="KB909_001953"
     CDS             complement(8188..8739)
                     /gene="coaC"
                     /locus_tag="KB909_001953"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBB6837968.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8736..9473)
                     /locus_tag="KB909_001954"
     CDS             complement(8736..9473)
                     /locus_tag="KB909_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBB6837969.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9470..10459)
                     /locus_tag="KB909_001955"
     CDS             complement(9470..10459)
                     /locus_tag="KB909_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6837970.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10717..11259
                     /locus_tag="KB909_001956"
     CDS             10717..11259
                     /locus_tag="KB909_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6837971.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11276..12361
                     /locus_tag="KB909_001957"
     CDS             11276..12361
                     /locus_tag="KB909_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6837972.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12373..13179
                     /locus_tag="KB909_001958"
     CDS             12373..13179
                     /locus_tag="KB909_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837973.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13180..14007
                     /locus_tag="KB909_001959"
     CDS             13180..14007
                     /locus_tag="KB909_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6837974.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14004..15077
                     /locus_tag="KB909_001960"
     CDS             14004..15077
                     /locus_tag="KB909_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6837975.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
BASE COUNT         4926 a         2770 c         3134 g         4504 t
ORIGIN      
        1 ttatataatg aaatcatctt atgaaaatta ctacttcatg tttagacaag agtagggagg
       61 actaagaata aatgtgttca aaaagacgtt caaaacaact aaataaacac gcttgtcgtt
      121 tagataagga acggtcgtgt tctgaaaaac actacgttaa gtttatgatg cgcacgatgc
      181 tgatcagttt atctgtaggt gtctatatgc atgtacccgt tcaggcaacg acacaaacca
      241 tcaaggtcgt acgtacctct gtttctgaga ccactgattc ccctatcact attactcata
      301 ctttcactga tgcaaatgga aaacagctac ttcctgcatt gacttcctat aataaagtca
      361 gttatcctcc aacgataaac cactactggt taattcctaa caaaacatta tggacatcgg
      421 aaaccggaag cagtgtgccg ctttctatct tttccgatat gactgatcct acaaaaggtg
      481 atcagttaaa acagatcact gatattttga atcatgcttt gacagatata aaggacggtg
      541 gaagcgcaca agtttcttat gtatatgaaa aagattattc acagtttgaa agaaagaaaa
      601 tcgatgttct ggcagggaca aaagtttcga tatctgatct ggtagaaagg ctgaagaacg
      661 cagatggaac acaaggagat atgtccaaag taatttcaaa caatgggaat atcgtggata
      721 cgactaatac aggaacatct actatttcct tgtcctattt tgatccaatt gctttaaaaa
      781 caatgactgc atctgctgtg atccatgttc gtgctgatca aacagctatc aaaggaaaag
      841 atcttcactt aagaacagga gagagttacg cccctaaaga tcttgttgaa tatgtaacaa
      901 aaagcgatgg aacttcagga aataaagaag aaatcaaaat gaacgggaca gtagatacta
      961 caactccggg agaatatccc gttgtattaa cttatataga ctcgaaaaca tcaaatgtgg
     1021 cagaaacaac agctgtagtt tatgtagaag catctgctgc ttcatcgact gtcatcactc
     1081 attttataga tagtcaaaca aataaagaac ttcaagcaga aacacatatg agtagtgtaa
     1141 atcgtattcc tgatttgcgc ctacctgctg aattttctga tcgagtgcca aatatagatt
     1201 tatcgactta tgaacaaaat gggaaagtca cttctatttc tgattggatg caagcaaacg
     1261 gattagacag aaaaagtcac tggtcggaga tccttgaagt acttcactca gaactgatga
     1321 ataataggaa gcaatcagga ggggaaatta cctttactta tgtttatata ccagacaatc
     1381 gttcattaga aggtcatgat cttattgttc atccaaacga aaaaataaac aaagaagagt
     1441 tgatccaatc agcaacaaat tccttaggta aacccgtacc gttaaaggat gtatcggtta
     1501 caatcaatga agtaccattg gaggatggtt atttgaccaa acaaacaggt gattttacga
     1561 ttatgtatag ttatcatgac ccgtattcac tccaagaact ccatgctcag tcactattac
     1621 atgttttacc attaaacaaa cagatagatc aaaaagaaca aaaaagacaa gaagaaagct
     1681 tgtcagaaaa aaaacaacaa atggctcatg cagtttctcc aacagggaaa gtaaaacaaa
     1741 caagaagcct agagttagca agaatatcta gaaaaatctc agaatctaat aaaacgataa
     1801 ggcaagaagc tcatttggcc ccacaagttt ctggattgga aaatgaaatt ttagagccta
     1861 aaataaaaca acaatcagaa aaagaatttg ttgctaaaca gtcggaagat cagaaggaat
     1921 cagatgacca gaaggaaacg aagaaaaaac gcttgtcaac tattgattcc accgatgagc
     1981 atctgcagcc gcaagtacca cttcctagtc cgggaacacc cgcacctggt ggaggtattc
     2041 cttcttctgc tttaggagat ttcatgcgag gtatggcagg aacatgggta tacgctaatc
     2101 gaaatgaatt tgacgcagat gactggttct gatttatatc tctatctgtt atagtcaaat
     2161 aagtagctga gtcatatgtt atttggcata atggagacga ggagggatag aaaaatgtta
     2221 gataaaacgt taccttacgc agaaatctgg atgacaagac cacttcaaca aaatgttcca
     2281 atcacgcctt tagcggaagg ttttgaattt cgattttatc aaaaagaaga tgaatctgct
     2341 tgggcggaga ttgagacttc cgttggggaa tttcaaacga cagatgaagc acttgagtat
     2401 tttcaacaaa actttgctcc ttatcctgaa gaacttgaaa gaaggatgtt ttttgtagag
     2461 acaaaaaaag gagaaaaagt agcaacctgt accgcttggc gaaaaaaatc aagagagcaa
     2521 gtgtatccgg tttttcattg gttagcagtg aaatcagatt accaaggaaa agggctcgca
     2581 aaagcattga ctgccagagt cttgcaagaa tttcctaccc tccatacgga cggaccaatc
     2641 tatcttcaca cacagacatg gagccatcag gcgattgctc tttataaaaa aatgggtttt
     2701 acttttattg ctgaaaatct agacggcaca cctaatccag attatgaaaa agttatgcag
     2761 gttttaagta aattagataa ataacgaaat ggtgaaataa gtcctcagta ttgggataaa
     2821 aaacgaaata gtcattcctc atatcttact tttttgagtt aatactatcg gataactaat
     2881 ggcatgccat acattcaaaa aagaaggggc agtgacaaaa gtattgtcac tgccccttct
     2941 cttgtttttt agcatgtttt atcgtttgat ttttttagga ataaaattct tgatgaacgt
     3001 aaatttttgg taatcgtttc gactatagag gtaaccaaat acactgaaaa caactgctcc
     3061 aataaaatta acaaataaat ccttcatagt atccatgatt cccacgtcta agtaaccatt
     3121 ttggatgatt gttttatctg ttttaccatc tgcattttga ctttcaatga ttgtccgagt
     3181 gatatctgga acatgataga cagtgtttcc gtctttactt aactccacac tattgatttg
     3241 ctggatgatc gtatcttttt gcatatcgaa ttgcagtaat ttatctgctg aaaattccac
     3301 aaactcccac ataacaccaa ctgtcatcga aaaacagaag gaaacaactg ctagtaataa
     3361 aggagtcaag ttcatggttt ttgtattttt attgagcaaa taaacaaggg aaaagccgac
     3421 acccccagct aaaaatccgc tgaatgcatg tagaaaagta tcccacattg aaaaatagcc
     3481 ataaaaatca cttaactctc ctaaaactgt tgaactaaaa ataaaagata acaaaatgat
     3541 ttctagcata tttggaatct gtatctttaa tatcttttcc agaaaataag ggatttcaaa
     3601 taaaattaat gtcagtaata aaagcattgt atttccccag tgttggttcc agacctgatc
     3661 cactagcata ataacgacga tgatacgtaa taaaatatag attccgtttg tgattctacc
     3721 tgcagttttt gtactgttcg taaaaaaggt tttcaaatga ttcataaaat aactccttca
     3781 tgtatatcct taattatact aagaagcgtg tgtttaccaa agctatatga cttaaagaaa
     3841 aacagagttg atattgtgaa aaaaatcact taatatagta taaggagaaa agggggatac
     3901 aaatgaaaaa attagttgct ggtttattaa cagccgttgc acttcttgct atgagcgcat
     3961 gcggcgcaga tcagaaaaat acagcgcaga caagttctag tacgaaggaa tctgccgaag
     4021 tatcatcagg cgcttctgaa caagtatata cagatccaaa agaaatgaaa gaatcttatg
     4081 atgtcgtgat tattggagct ggtggtgcag ggatggcagc agctatcgaa gcaaaagatg
     4141 ctgggttgaa tccagtaatt ttggaaaaga tgcctgttgc cggaggaaac acatctaaat
     4201 catcaagcgg tatgaatgct tcagaaacaa aatttcaaaa agaagaagga atcaaagact
     4261 cgaatgatgc cttctatgaa gaaacgctaa aaggtggtgg aggaacgaat gataaagaaa
     4321 tgcttcgata ctttgtcgat cactctgctg atgcggtcga ttggctagat caaaacggta
     4381 tcaaactgga caacttaacg atcactggag ggatgagtga aaagaggaca catcgtccgt
     4441 ctgatggctc ggctattggt ggatacttag tggaggggtt attgaataac gtccatgagc
     4501 gggaaatccc tatttttgtc aacgcagatg tgacagacat taagaaaaat ggggaaacgg
     4561 tcaatgaagt gactgtacat gttcaaggag aagaaccaaa agaggtcacc ggaaaagcaa
     4621 tcgtagttac cacaggcggt tttggtgcca gcaaagaatt tattgaaaaa tatcgtcccg
     4681 atttagctga ttatattacg acaaatcaag aaggatcaac tggagatggt atcaccatga
     4741 ttgaaaaatt aggtggacaa accgttgata tggataaaat acaaattcat ccaactgtgc
     4801 agcaggatga gggggtcttg attggtgagg ttgttcgcgg agaaggagca atcttggtcg
     4861 atcaagaggg gaaaagattt gtcaatgaaa tggatacaag ggataaagta tctgcagcaa
     4921 ttacagcatt gcctgaaaaa tcagcttatt tgatttttga ccaaggcgtg cgtgatcgtg
     4981 ccacagctat tgaattttat gaccaaaaag gatatgtcac aactggaaag acaatggaag
     5041 aattagcaga aaaaatcgat ttaccaaaag aaacactagc aaaaacagtt gatggatgga
     5101 atacggatgt tgcggagaaa aaagatgctc aattcaaccg tgccacagcc atggaacatg
     5161 acttatcgtc tccgaattat tatgcgatca aaatcgcacc aggaatccat tacacgatgg
     5221 gcggtgtgaa aatcaatacg aacactgaag tattagataa agaaaaccag ccaattaggg
     5281 ggttatatgc tgctggtgaa gtcacaggtg gcttacatgg aaacaaccgg atcggtggaa
     5341 attcagttgc ggagatcatt atttttgggc gacaagcggg catacaagca gctcgatttg
     5401 cttcggaaaa tgaatgaaat agaacgtaaa taaaaagagg ttgtgaaatc agcgttttga
     5461 gctaataccg agggtcagct gattgaacac tgtttagtga agaggttgtg aaaaagctgc
     5521 cctgcatcaa gtaataagaa cagccaagta aaaacagctt cttatgtttt taacttggtt
     5581 ggacttatta ccgcagatgc aagcttttga acaccgttta ttcggaaaaa gagcgtggga
     5641 caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaagcagaag
     5701 aaattccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattt
     5761 cttcttattt cttggagtta aacgcttctg tcccagcctc ttttttgatc agcatgattt
     5821 tattcagtta tcttcaaaat gatttttccg atgtttttgt ttgcttccat atattcatgc
     5881 gcttgtttga ctgcgctgaa ttggaatgta cggtcaatga ttggccgaat cttgccattt
     5941 tctagaaaag gcccagcttt ttgcataaaa gtttgtgcga gctctgcttt atactgatca
     6001 cttctaggtg tcaataatgt accaagcagt tggacacgtt tcccaatcaa tacaccaagg
     6061 tctatctcag gcacgatggt cccacctagc ataccaatca agacccaacg tccatcaacg
     6121 gctatagaag ctaaattctt ttcccagtaa gaagcgccga tgaaatccaa aataacatcg
     6181 actccccgac cttcagtgat ttttcgtacc tcttcttgaa agtcttgttt tttatagttg
     6241 atcaattcat ctgcaccaag ttctttacaa aaggcgagtt tttcttctga tcctgcagta
     6301 acgatgattt tcgcgtgaga aagctgtcta gctaattgga tcgctgctgt tcccacacca
     6361 cttgctcctg catggatcaa gacagtttcg ccttcttgta attttccaag ccagtaaagt
     6421 gtttgataag cagtcaaaaa aacttctgag attccagcag cagaaacata gtctagcgta
     6481 tcagggagaa ggattgcacg atcggcaggc atcacagcat attcggcata accacctaga
     6541 ttgactaatc cgtatacttt tgtcccagga gtaaaagtgg agatatcact tttattctca
     6601 actacctctc cagctacttc gactcccaaa atagggtagg gaggtttcaa agagactgat
     6661 tctcttttca taatatctgt tcgattgaca gctgctgtat ggactttgat cagtaattcg
     6721 ccttgttttg gtttaggaac aggcacttca atttgttcta atacatctac agaaccagga
     6781 tgcttgattg aaatggcacg catggatcta ttcctccttt gcccattctt ggaatgctgt
     6841 attcaactct ttgctacctt cagaaagtac tagagtcgta cgagaaatat ccgtttcttc
     6901 cactagagcg gcaagtacag cagcaactgt agagcgagtg atcgtttttg atgccttctc
     6961 attaggctta gttaattgaa tggaagtaac ttcttcatcg ttagtcaatg tgactggttg
     7021 aagaatgaca aaatctaagt tagttcgttt cagccattca tctgcataat gtttagtaat
     7081 ataataatct gtcatggact caggccattt tgctggttca tctgcataaa cagcactgac
     7141 catcagatag cgagagacat gcgcattttc agctgcgatc actgttttga ttgcgccatc
     7201 caagtctact tgcagaagat tctttccttg agagccggca gcaaaaatca atacatcgat
     7261 gcctttgaat gcttcggtca ttttttccac ggaccaagtt aaatcaaaag agacatacga
     7321 aacattctct ttttttacta atgtttggga agcaacatct ctcacccctg caaaaatttc
     7381 atgggaactt ggagctaaat cttttatcag gtgtcggcca atttgtccgt ttgcacctac
     7441 aacaaaaatt ttcatttgga tcatcctttc gacgtcaaat ctttccattc aatagtaaca
     7501 ccaaaagaga aaaaaatcag agatcggcta cgatgactat cagttagtaa gagaagggtg
     7561 cttgaagtat cttaacaaga cattgcatac tgctgcagtc gcaagacctg cgacgattcc
     7621 ttcaggtata ccacttgtaa aaataaccgc tagaatagct gaataaacag catttaaatt
     7681 tgttccgatg actttggcat aatcttgctg gaataaaaag tagatcatat tcatcactaa
     7741 aatcgtattg gtcaatgaac cggaaagtcc agctaagaat aaagaaacgg aatctgcttt
     7801 ttgtttcatt agtttgcgca gacctttata aacgaaataa ggaaccaccc caatcaagat
     7861 gcgaggaata aacgcgatca gcaaggcttt ccagcttcca tgttctgttc cgatgactgg
     7921 gataaacgga gaaaagacaa aagacaaagg tgtttggata actgtgctac ggatcatgct
     7981 gatcagtcca aatgtaccgc caagaaaagc acctagtctt ggtcctaaaa cgatcgaagc
     8041 aatgattaca ggaatatgca tggttgttgc attgattgga ccgataggga taaaacctaa
     8101 aggcgtaaca gctaataaaa tcaaaatagc taaaaacatc gcagttaatg taaagttttt
     8161 tgtatttttc ataagtactc cttttttcta agcatttctt tcattaagag tcagcatgac
     8221 ctgttcgatg atcgtctgaa tatcagctaa ggcacctttt ccaaaatctc cacaagctaa
     8281 aagagattct cttggttcaa tttcctgata gccgacagat ctcaatgttt ccagattacg
     8341 ctgagtgatc gggttttgat acatattcgt gttcatggca ggggcaatca attttggtgt
     8401 tcccactgga agcgccattg cgactgttga aagaagatcg tctgcaatgc cgtttgctag
     8461 cttgccgata atgtttgctg tagcaggcgc gatgagaaac aagtcagctt gttttgctag
     8521 ttcgatatga ttgattacct gcggatttga ttcttgcatg acgtctgtat ggactgcgcg
     8581 cttcgacaga gattgcaagg ttaatggcgt gataaaatgt gtgctgcttt tagacataat
     8641 cacatctacc tgggcaccta atttgacgaa ttgacttgta agatcagcgc ttttgtaagc
     8701 agaaatactt ccagtaacgc ctagtaagat ctttttcatt ttgattcctc cagtctaatt
     8761 ttctcagtaa tcaatgcagc aatctcagat ttactttgag cttcttccac tgttccatct
     8821 ttagataaga gatagccgtg gtgtgtctcg ccatggattt ccgtcaaatc atttgcgaaa
     8881 ataaaatcag ttttgttatt tatcagacta ttttttgcga ctgccagaag agattccttt
     8941 ggtacatcta ctaatagttt gaaaccaatg atttttgctt ttggctgcca ttcacgtaga
     9001 taagaaatga tttttggtgt tttcttcaaa acgagcacaa gatgctcggt gttagaagag
     9061 atctttgaaa cagtggtatc tgtctgttca ttttccgcaa accaattgtc cagttcttct
     9121 tgcgttgaag aagtgggtag gttttttgcc agctgttctt ctgaaaaact aaaagcagga
     9181 gtaaaatcac tgactgccat actgtggata atcgcatcgt agtgttcttt tttcgttagt
     9241 tcttctaatt gtaaaaataa gtccagtgca gattcgatcg tataaatcgt tatattggag
     9301 tgtcttttcg gtttcagtgc ttgtttcgta gtcacgtaat cgattgtggt atccggattg
     9361 gcagctaaat aatcagctaa tgcttgccct aatcgtcctg tcgaatgatt tgtaatagca
     9421 cgtacttgat cgattttttc agtcgttcct ccagctgtga ttagaatctt catttatggt
     9481 cacctacatt tactagtgtt cttccttggt gtgttccagc aagtagttta gatgctgttt
     9541 caggcaattg atccagagta atctcttgga cgaccagttc atctgcaatc tgcaaatccg
     9601 ccatctgttg ccataaagaa agacgttgat ctattggtac attgacagaa tcaattccaa
     9661 tcaactggat gtttcgcaga ataaaaggca agacagtcgc gtttagtttg attcccccag
     9721 cattgccaca taaagctact gcaccgttat aagagatcaa tggaagaaga ctgcttagct
     9781 gctcgccacc tactgtgtcg atgacatagt cgatttgctg ttttcctaaa gcttttgttg
     9841 tctctggcag aaattcatca ggtcgtacga cttgcaaagc acctagactt tttagccatg
     9901 tgacagactc ttcttttctg gaaaaggcaa tgattgactg gaatcctagt ttatgtaaca
     9961 gggctatcgc tgtactgcct acaccgccag aagcaccagt aacgacaact tttttatcgg
    10021 aggtcatacc ttgacggatt aaagcgttca cacacaacat agcagtaaac cctgctgtac
    10081 caaggatcat cgcttgacgc agcgtcatat tttttggtag aggaactaac cagtctcctg
    10141 gtactttttg atattggcta taaccgcctg gatgggtgac gccaagccca aaaccagtag
    10201 caagtacaag atcttctttt gaaaaacgtg gattgttact ttggacgaca gttccggata
    10261 aatcaatccc tggagtcatc ggatatgttc gtatcacctg accagactcg ctcattgcca
    10321 atgcatcttt ataattgaca tcagaatagg caatttttac caagacttca ttttcagcca
    10381 actcagtaaa tggcagatca ctgattgctg tatggaaaac aggttccttt attacctgaa
    10441 aagatcgaaa agcgttcatt cgtgagacac tccttttaaa attttctttt atcataccat
    10501 aaagcctact cttttattct tgttcttccg taaatttaga caaaaattag gtgaaaaata
    10561 aagaatcaaa caactagaat ttattccaaa agataaagaa atattcagca aaaaaaattt
    10621 tacaaagggt tgcctttttc aataaatttc gtatactaat acgagtggta gtaaacagga
    10681 agtttactat tagaaaactt cgattcggag gaaattatgg aaattggtga gaagttaaga
    10741 aatttgcgca tccaaaagaa tttgacacaa gaagaactag gcgaacgcac agatttgtca
    10801 aaagggtata tttcccagtt ggaacgagat ttaagttcac catcaatgga aacattcttt
    10861 tctattcttg aagtcttagg tgtgactcca gaagaatttt ttcatcaaga agcagcgaat
    10921 ctgcaagtgg tttattcaaa agaagatcat acggtttatt tcgatgaaga aaacgggtat
    10981 gaattggaat ggctcgtggc tgattcgaat gaaaaagaaa tggagcctgt cttgctgact
    11041 tttgaaggtg caggagaata taagacgttt gaaccttcat tatctgaaac gtttattttt
    11101 gtattagaag gggaattaga gttaagctta ggagagacgg tctatgtggc aaaagcagga
    11161 cagtcgatct attatcaagc gacaaaacaa catcaattaa ggaatcatct caaaaaacga
    11221 acaaaagtat tgattgttgc aacgcaatca tatttgtaat atagggggta aaaacgtggg
    11281 gaaaccaatc atttcatttg atcaagtagt gaaacgctat gatgatgaaa cagtattaaa
    11341 aaaagtaagt tttgagatcg aacaaggaaa attttataca ctgcttggtc cttccggctg
    11401 tggtaaaaca acgatcctac gtattatagc tggattcacc gaagctacag aaggggacat
    11461 ctattttgaa gggaaacggt tgaatgattt gccagctaat aagcgacaag taaatacagt
    11521 cttccaagat tatgcacttt ttcctcatat gaatgttttt gataacgttg cttttggatt
    11581 gaagatcaag aaaatgtcca aatcagatat cgaaaagaag gtaaaagatg ctttgcgtat
    11641 ggtccagctt cctggatacg aaaaacggga gattagtgaa atgtctggtg gtcaaagaca
    11701 gcgtgtagcg attgcacgag caattgtaaa tgaaccgaaa gtattgctat tagatgaacc
    11761 gttatcggcg cttgatttga aactacgtac agatatgcag tatgaactgc gggatctgca
    11821 acaacgatta ggaatcacgt ttatttttgt tactcatgac caagaagaag cgttggcaat
    11881 gagtgatgag atttttgtca tgaataaagg gaaaatcgtc caaagtggta cacccgtaga
    11941 tatttatgat gagccaatca atcatttcgt tgctgatttt gttggggaga gcaatatcgt
    12001 ggacggtgta atgatcgaag ataatctagt tgagtttgtt ggtaagcaat ttgaatgtgt
    12061 cgatggcggg atgcgtctaa atgaaccagt tgaagttgtt ttacgcccag aggatttgac
    12121 gatcacgaca ccagataaag gaaaactagt cgtaacggtc gatactcagc tgtttcgtgg
    12181 tgtccattat gaaatcatct gttatgatga acagcaaaat gaatggatgg tccattcaac
    12241 gaaaaaagct aaagaaggaa gcaaagtagg attggccttt gagccagaag atatccatgt
    12301 catgcgtttc aacgagtctg aagaagaatt cgatgcacgt cttgacagct acgaagaata
    12361 ggggggacaa gaatgaaaac aatgcgcagg atctattccg tcccttatat tttgtggctc
    12421 ggtttattcg tgatcgcgcc tgtattaatg atcatttatc aatctttttt tgatatgaat
    12481 gggcaattca cgctgaataa ttatctatct tattttacgt cggggacatc gctttctatg
    12541 acgatcaatt ctgtatggta tgcatttttg atcacgtttt tcacgctgat catcagttac
    12601 ccgactgctt attttttaac aaaactgaag cacaagcaat tatggctgat gctgattatt
    12661 ttgcctacat gggtgaatct gctgcttaaa gcttacgcat ttattgggat tttcagtgtg
    12721 cacggcagcg tgaatcattt ctttgatttt atcgggatcg ggccgaaaca gatattattc
    12781 acagacttca gttttctgtt cgtggcaacg tatatcgaga ttccatttat gattatgcca
    12841 attttcaatg cattggaaga gatgaatcct tctttgatca gtgctagtag agatttaggc
    12901 gcgaatagct ttgagacctt ccgacgagtg atttttccgt tatcattaaa tggtgtgaaa
    12961 agtggtgtcc aagcagtatt tattccttct ctttctttat tcatgctgac tcgtctgatt
    13021 ggcggaaatc gggtgatcac tttaggaacg gctatcgaac agcatttctt ggttacacaa
    13081 aactggggga tgggttctac aatcggtgtg attttaatca ttgctatgtt catcgtgatg
    13141 ctcctgacag gcgagaagaa aaaaggaggt cgctcataaa tgaaaaaatt taaatggtcg
    13201 tatctttatt tagggatcgt ctttttattc ctatatgcac cgatcttcta tctgattttt
    13261 tattccttca atgaaggagg aacgatgaac agctttacag gatttacttg ggaaaattat
    13321 gaagctgttt ttgaagatac acgtttgatc attatcgtat tgaatacgtt catgctggct
    13381 ttcttatctg cattgatcgc cacgatcatc gggacatttg gggctatggg aatctattac
    13441 acgaaaaaac gacgtgcacg gacagcgttg ttgagcatga ataacatctt attagtctct
    13501 cctgatgtta ttatcggtgc tagtttcttg attttcttta cactactagg attcggatta
    13561 ggttttcaga gtgtattgct ttcccatatt gctttcagca ttccaatcgt cgtcttgatg
    13621 gtcttgccaa aattgcagga aatgaacgat tcaatggtcg atgcggctag agaccttggt
    13681 gctaataatt tccaagtagt caaaaatatc attttgcctt atctttctcc aggaatcata
    13741 gctggatatt ttatggcatt tacctattct cttgatgatt ttgcggttac atttttcgtc
    13801 acaggaaatg gctttacgac gctctcagta gagatctatt ctcgtgcaag acaaggaatc
    13861 agtttagaaa tcaatgcgct aagtgcgtta gttttcttgt tctccatgat attggtcatt
    13921 ggatactact ttattagtaa agaaaaccgt ccaaaacggc tgaagaaaaa cagaagagta
    13981 cgcgaggggg tggcacggct gcgatgaaaa aattacaatc tctgttttta ggtattctca
    14041 tcattattgc ggtgctgctg cttggtgttc gtcaacttga aaaaacaagt ggcatgagtg
    14101 gagcaaaggt acttaccatc tataactggg gagattatat cgatcctagt ttgatcacga
    14161 aatttgaaaa agaatatgga tacaaagtga attatgaaac atttgattct aatgaagcga
    14221 tgttcacaaa aatccagcaa ggtgggacaa actacgacat cgctatacca agtgaatata
    14281 tgatccaaaa aatgatcaaa gaaaaactag tacttccatt agatcattcg aagatcaaag
    14341 gattaaataa tattgatcca cgatttttag acttggattt tgatccagat aatcagtatt
    14401 cgattccata tttttgggga actttaggga tcgtatataa cgataaattc tttgatgcaa
    14461 atcaaattaa gcattgggat gatttgtgga agccggaatt aaaagacagt ttgatgctga
    14521 ttgacggtgc acgagaagtt atggggcttt ctttgaatag tttaggctat tctttgaata
    14581 gtaagaatat ggcacagctg acagaagcag caaataaatt gaatcattta acaccaaatg
    14641 tcaaagcaat cgtggcagat gagatcaaaa tgtatatgat caatgaagaa gcctccgtgg
    14701 cagtgacatt ttctggcgaa gctgccgata tgatgtggga aaatgaacat ttacattatg
    14761 tgatcccacc agaaggatcc aatctttggt ttgataatat cgttatgcca aaaaccgtga
    14821 aaaataaaga aggtgcctat gatttcatca actttatgct agaaccggaa aatgcggcac
    14881 aaaatgcaga gtatattggt tattctacac caaatgaaga agcaaaagcg ttattgccaa
    14941 aagacatttc gtcggacgaa caattctatc catctgatga cacgatctcc catcttgaag
    15001 tctacaaaga tctaggatcg aaatacctag gcatctataa tgacctattc ttagaattca
    15061 agatgtatag gagataatgg caaaactcag taagaatggg gacttatcaa cgttctaaag
    15121 agctaaaaat cgtccttttt ctatctgagt tttccaatct tctaccaaaa gcggatgaaa
    15181 cgccgctttt tttgtgttat tttatttttt ctaccacgtt tttctaccag agaaaagtgg
    15241 acaaaaccat tgtaaaatag ggcccgagac gggctagtaa atctaagatt gaaaaagtta
    15301 cagaaggata aagtaattgg aaactatgca aata
//
LOCUS       DADVXK010000068        15223 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.069, whole genome shotgun sequence.
ACCESSION   DADVXK010000068 DADVXK010000000
VERSION     DADVXK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.069"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            100..1125
                     /locus_tag="KB909_001961"
     CDS             100..1125
                     /locus_tag="KB909_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6837976.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            1419..2528
                     /locus_tag="KB909_001962"
     CDS             1419..2528
                     /locus_tag="KB909_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6837977.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            2611..3507
                     /locus_tag="KB909_001963"
                     /pseudo
     CDS             2611..3507
                     /locus_tag="KB909_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            3523..4347
                     /locus_tag="KB909_001964"
     CDS             3523..4347
                     /locus_tag="KB909_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837978.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            4379..5689
                     /locus_tag="KB909_001965"
     CDS             4379..5689
                     /locus_tag="KB909_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBB6837979.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            5837..7096
                     /locus_tag="KB909_001966"
     CDS             5837..7096
                     /locus_tag="KB909_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6837980.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            7106..7978
                     /locus_tag="KB909_001967"
     CDS             7106..7978
                     /locus_tag="KB909_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6837981.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            7990..8820
                     /locus_tag="KB909_001968"
     CDS             7990..8820
                     /locus_tag="KB909_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6837982.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            8860..11043
                     /locus_tag="KB909_001969"
     CDS             8860..11043
                     /locus_tag="KB909_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6837983.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            11104..12324
                     /locus_tag="KB909_001970"
     CDS             11104..12324
                     /locus_tag="KB909_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBB6837984.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            12321..13781
                     /gene="gtfA"
                     /locus_tag="KB909_001971"
     CDS             12321..13781
                     /gene="gtfA"
                     /locus_tag="KB909_001971"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBB6837985.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            13858..14964
                     /locus_tag="KB909_001972"
                     /pseudo
     CDS             13858..14964
                     /locus_tag="KB909_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
BASE COUNT         5168 a         2317 c         3013 g         4725 t
ORIGIN      
        1 attatgatta cagtgcctat ttttaacgaa atttgcttat tttcaaaatg tatgattata
       61 tgttagtaaa cactttcaaa tatgaaaaga ggagctatta tggtaggaat tagggatgtt
      121 gcaaaacggg cgggtgtgtc cattgcaaca gtatcgcgcg tgctaaatga ggatccgaca
      181 ctttcagtaa ccgatgaaac caaacgaaag attgcagaat cggttaattt ttatcattat
      241 gtcaaaaaaa gtcccgttgc aaaaaattta acaaatattg cattaataac gacagtttct
      301 gaagtagatg agttggaaga tccctatttt cgaacgattc gcagagggat tcaagtcgaa
      361 gcagaacaaa gcaaagtcaa tttgaagaaa attattcgtt tgtcagaaac accgttggag
      421 caagacgatt tgctaaaatg tcaaggtgtg ttgattattg ggcaggtgct atcttctgtg
      481 attgaagaag tatcagcaat taattcgaat gtcgtagtga ttgatgaccc tagtattgaa
      541 gctgaagtag atgcagttta tactgattta acaaaagcaa cgaatcagca tttagatcga
      601 ttgtataaaa aaggacaccg aaacattgcg tttatcggag gaggacgtgt tcgtttagat
      661 agccaaggaa ataaacacgt gtcagatgat gattatcgaa aaatagccta tgagacgtgg
      721 atgaaacaaa aaggattaga aaaatatagt caaatttatt tagaaggctg gaccacactt
      781 gacggaatgc aggcagcaga tttacttttg aaaaaacatg ctaaagataa gttgccgact
      841 gctatcatgg taggaaatga tcctattgct gtgggggttt atcgttcact tcaaaaaaat
      901 ggtctacata ttccagaaga tatttcgatt gtgagttttg ataatattga agttgctgaa
      961 tttttaacac ctgcattaaa tacggtgaat gtgaatacag aagaaattgg aaaactagca
     1021 gttcgcatgg ttaatgaacg aataaaagaa gttagaaatg tttcgatcaa agtgattgtt
     1081 tctaataata ttattgttag agaaagtgaa aaaaatatcg attaaaaaag taaacatcca
     1141 aaaaagggtg tttacttttt tgtttactaa tatttttagt aaaaaatctc gacaaaacat
     1201 taagtaaaca gttatggtgt tgttaacaaa aagaaaacgc attcaaaaca ggaggaatta
     1261 agatgaaaca tttcaaaaaa atagctttaa cagggatagc tgttttaact gggacattac
     1321 tcgcagcatg tggtggggga gatagtaatt ctaaagacgg gcaagtaact ttaagctatg
     1381 cgagttgaga tactgaccaa gctccaggac taagaaaaat gttagatgaa tttgaaaaac
     1441 aaaatcctga tatcaaagta gaaatggaga caacgccttg ggatcaatat tgggttaaat
     1501 tagaagctgc aacaacggga ggtaatatgc cagatgtagt aaccatgcac tctagcgaat
     1561 cctataaata tatgtcacag aatgctttga tgggacttga tgatgttatc aaagaaaatg
     1621 atattgacat gggaaacttt actgaaggaa ttgctgattt ctatacgctt gaagacgaac
     1681 tatacgcaat ccctaaagat gcttctgtag tggggctatg gtacaacaaa gaattatttg
     1741 ataatgcagg tgtcgattat ccagatgaaa catggacatg ggaaacactc agacaagctg
     1801 caattgattt aacagatgaa tcaaaaggca tctatggttt tgcatcacat attggaacag
     1861 agactggcta ctggccattt atttatcaaa atgggggaga agtatttgcc gatgacaata
     1921 caaaatcagg tttgaatacc ccagaagcac aagaagcttt agctttttat cgagatattg
     1981 cacttgttga tcatgcttca ccaacaatta cagaattaca agatcctgat aagttaagtc
     2041 gttttcaatc aggtagatta gcaatgatga ttgaaggaaa ctggtttgca ccgggatttt
     2101 tgaaaaatga ctatctagtt gaaaatgttg cttctgccgt gttacctaag ggaaaagtta
     2161 atgcaacaat tacaaatgga cttggttggg ctgccagtgc gagtacaaaa tacccagaag
     2221 aagtgaaaaa actaatggca tttttagcta gtgaggacgc caataaaatc caagcggaaa
     2281 cgggggcatc aatcccagca ctaaaaggct ttgaagacga gtgggctgct tcttcagata
     2341 caattgattt gagtgctttt ggaaaaatgt tggagtatgg agtccctcgt ccatacaata
     2401 aagatggatt acgagctgaa caagcagaag ttcaaattat taaccgtatt ctgtctggtg
     2461 aagtaactgt tgaagatgga accgctcaaa ttgaaaaaga agtcaatgcg atattgagcg
     2521 gaaattaaat tagttaatta tacaatatac aggcgaaagg attctatttc gtctgtatat
     2581 taatggatga ataccaaaaa gggggatatt atgaaaaatc gaatttttgg aaaatatcgt
     2641 aaagatcaag tgatatgggg ctatattttt atttttccaa cggcattagg attaatttta
     2701 ttaaatatat ggccagcaat tcaaacagca attttaagtt ttcaaaaaac ggtagggttc
     2761 ggtgatactg aatgggtcgg attaagaaat taccaaaaaa tgtttgcaga cggtgaagtt
     2821 tttcagtctt tattaaacac attaatttat gcagtggttt cgatacctag tattgttgta
     2881 ttatccttgt tggtggcagt tttaatgaat agaaaagtta aaggattgtc gatttatcgg
     2941 acaatttatt ttctaccagt cgttgctgca ccatccgcag tcgcaatgat ttggcgctgg
     3001 atgttcaata atgattatgg actgattaat aacatgttgg ctaaaatagg tctcgatgga
     3061 ccagcatggt taacggatcc atcgattgcg atttattcta ttatcattgt aggagtttgg
     3121 agtgctattg gttataacat ggtgttatta ctagccggct tataagaaat tcctaaagat
     3181 tattatgaag cagcggaaat tgatggtgct agtccaatcc agcagttttt caacattacg
     3241 ttaccattag ttacaccaac attatttttt gtagttgtaa caacagttat caatgctttc
     3301 caagtatttg atgttatttt tatgatgatt actcctaata gtaccgccat gtttaaatca
     3361 caatcattag cctatttatt ctataaacat tcatttattt taaatgacaa gggatatggt
     3421 tcggcaatcg ttatgttcct tttagtgatt atattaatta ttactgcaat tcaaatgaag
     3481 ttgcagaaaa agtgggtaaa ctattaagga ggctatcaaa ttatgaaaaa taaatttttt
     3541 tcaaatgcgc caatccatat catgcttatt ttaggtggta ttgcaatggc attacctttt
     3601 atttggatga ttttaacttc agggaaaacg ttggttgaat ctacccaaat tccacctaca
     3661 attttccctg agaaatttca gctaagtaac tatcaacaag tacttgattt attaccattc
     3721 atggcttttt atatcaatac atttttaatg gttgttggac gagtgattgg ctcggtttta
     3781 ttttcagcaa tggctgcata tgcttgtgcg cgtctaagtt ttccagggaa aaatatcctt
     3841 ttcagcttag tacttattca aatgatgatt cccggttcca tttttattac tccacagtat
     3901 ttattagcac aaaaattggg tattttaaat acaattccag cattaatatt accaggggta
     3961 gttagtgcgt ttggtacgtt tttattaaga caatttttct taggtttacc tgatgaattg
     4021 gaggaagcgg cctatttaga aggtgccaat atttggacga tctttttcaa aattatgttg
     4081 ccgcttgcta aatcaggatt ggttgcactt ggaatattca cagcgttgtt tgcatttaaa
     4141 gatttaatgt ggccattgat tgtcaatact tcaattgata agatgccttt agctccggga
     4201 ttagcaaact tacaaggaca atatgccacg aacttcccac aattaatggc aggttcgtta
     4261 ttagcaattt ggccaatagt tgtgatattc atcgttttcc aaagaaaatt cattgaagga
     4321 attgctacaa caggtagtaa attataaaac tattaattag tgattggaga gtaagtacat
     4381 gacaaaaatt acatttattg gtgcaggaag tactattttt gcaaaaaacg tattaggcga
     4441 tgcgatgtta actccaagtc tacaagatgc acatattgca ttgtacgata ttgatgaaaa
     4501 acgactaaaa gaatcaaatt taatgcttaa aaatattaat aaaaattcga atgaaaatcg
     4561 tgctgatatt gtttcttatt atgatcgcaa agaagcgtta agagaggctg attttgttat
     4621 caatgctatt caagtgggtg gttataaacc ttcaacagtg attgattttg atattcctaa
     4681 aaaatatggg ttgcgacaaa ctattggtga caccatgggg attggtggga tttttagaac
     4741 cctacggaca ctaccagtaa tgttagactt tgctaaagaa atggaagaag tttgtccaaa
     4801 tgcttggtta ttgaactata caaatccgat ggcgatgtta accatgggtg ttttaaaagc
     4861 gacgagtatt aagactgttg gtttatgtca tagcgttcaa gtatgcgtac cagaattgtt
     4921 tgagcattta ggaatagccg atcaatatga cttaaatgac tttcaatgga aaattgcagg
     4981 cattaatcat atggcattct tgttggaaat tacaaaaaat ggggaagatt tctatccaac
     5041 aattcgtcag ttagctgcag aaaaaccaaa tccacatcca gattctgtac gttttgaatt
     5101 gttgaaacgt tttggttact atattacaga atcaagtgaa cacaatgcag aataccatcc
     5161 atactttatt aaatcaaaat acccagaatt gattgacgaa ttagggattc cgttggatga
     5221 atacttacgt cgttgtgaac aacaaattaa tgattgggaa agcatgcgag aggacattgt
     5281 aaataatggg gagttaacac atacgagaag ccgtgaatat gcttcatata tcatggattc
     5341 tattacgaca ggaactccgt cagtgattgc aggaaatgtc ttaaataaag gcttaatcac
     5401 aaacttaccg acagatgttt gtgtggaagt accttgttta gtcgataaaa atggcgtgca
     5461 accaacctat gtcggtgaat tgccaacaca attagctgct ttaaatcgga cgaatatcaa
     5521 tgttcaagaa ctgacagtag aagccgcttt aacactagat aaatcaaaaa tttatcaagc
     5581 agcgtattta gatccacatc tatcatctga attgtcttta acagatatca aaaatttagt
     5641 ggatgattta atcgaagcac atggggacta tttacctgaa tataattaaa aagaagctga
     5701 aagagtaagg aattttcaat tccttactct tttcttagtt aaatttagta aaaatattga
     5761 caaaacactt agtaaacagt tacattagtg ttaacaaaaa gaaaacgcat tcaaattgta
     5821 taaggaggag cataaaatga agtggtctaa aaaaattatt ttagcttgta tagcactagg
     5881 agcaacgatc tctttgactg cttgtggaaa aaatcaggaa gatgcaagcg gtaaggtaga
     5941 aatagagttt tttaatcaaa aaaaagaaat gactcaaacg attcaggaga ttgctaaaga
     6001 ttttgaagca aaaaaccctg atattcatgt aaaagttgtg gatgtaccga atgctggtga
     6061 agtaattaaa acacgtatgc ttgcaggcga tgtaccagat gtcattaatc tttatcctca
     6121 aagtatagaa ttgaaagaat gggcgaaagc tggttattta gaggacttaa ccgaagaacc
     6181 gtatttagag aatatcaaaa atggatatgc acaacgtttt gctattgagg atcgtgtata
     6241 tagcatacca ttaaccgcta atgtctatgg tttttactat aacaaaactg cttttgagga
     6301 aatggggatt caagcaccag aaacttgggc agaatttgaa aaaatagtag ctgagattaa
     6361 agatcaaaac aaagtaccgt ttgcgattgc aggagcagaa ggctggactt taaatggtta
     6421 tcaccaacta gctatagcga ctgctgctgg tggtgaagag gaagcgaaca atgtttggcg
     6481 tttctcagaa gttaatggaa ttaatgctga aagcaaagaa atgcaaaaag attttaatcg
     6541 attagatttg ttaagagaac caaaagcttt gcaaaacaac tggcaaggtg ccggttataa
     6601 cgatacagta gttactttta caaaaggtga tgcgttgatt atgccgaatg gttcatgggc
     6661 aatgccgatg attcattcac aaaatccaga ttttgaagta ggaacttttc cttttccagc
     6721 agatgaagca ggtcaaagtc taacgattgg cgcaggagac ctagccttat cagtttctgc
     6781 aacttctcaa cataaagaag aagccaaacg ttttgtagaa tatatgacaa cacctgaagc
     6841 gatgcagaaa tattatgatg tagatggtgc accgtgtgct gttgagggcg ttatcgagaa
     6901 tactcaggat tcaccattaa gtggtttaac tgaacttgct tttactgatc gtcatttagt
     6961 ttggttagcc aaagattgga atagtgaaaa tgatttttat accttaacaa caaattattt
     7021 acacaatggc aatcaaaaag ccatgattaa cgcattaaat gctttcttta atccaatgaa
     7081 agctgacgga aggtaggaaa ataaaatgaa aataaaagaa attttaaatc gttactgggc
     7141 aatcattttt gtagcaattc caattatttt gcagatgatt tttttctact ttccaatggt
     7201 tcaaggtgct ttttacagtt taactaattg gactggtctg acttataatt ttgattttgt
     7261 gggtttgaac aattataaga ttcttttttc tgatccgaag tttatcaaat cgattggctt
     7321 cactttaatt gtgacgcttt gcatgattgc tggacaaatt ggttttggta ttttgattgc
     7381 gcgggcgttg aacgcaaata ttaaagggaa aacattcttt agagcatggt tcttttttcc
     7441 agcggtctta tcgggcgtgg ttgtttcttt agtatttaaa caaattttta actatggttt
     7501 accaaaaatt ggtagtatgt taggcattga atttttacaa accagtcttt taggaacaac
     7561 atggggagcg atttttgcag taatttttgt tttactttgg caaggaattg ccatgccagt
     7621 catcattttc ttagcgggtt ttcaaagtat tccacaagaa attattgaag ctgctagaat
     7681 ggatggggcg aatgataagc aaattttttg gaatattgaa atcacctact tattaccaag
     7741 tatttcaatg gtatttatta tggcattaaa aggtggctta acagcatttg atcaaatttt
     7801 tgctttaact ggtggtggac caagcgatgc cacaacatct ttggggttac ttgtttataa
     7861 ttatgctttt aaaaacaatc agtttggtta tgcgaatgct attgctttag tcttatttat
     7921 cttaattggg attgtttcac tggcacaatt aaaattatcg aaaaaatttg aaatctagga
     7981 ggtttcccaa tgaaaacatc aaaagaaaaa aatatttcta aatacttgct tttattatta
     8041 gggggcttca tgattttagt tcccttagtt tcaacgctat tcggttcatt taaaacaaca
     8101 cccgatatta tgaataattt ctttcgtttt cctaatccag cgactttgga aaatttccga
     8161 agattgttag cggatggaat tggtcattac ttttggaatt cggcaatcat cacaatcatt
     8221 gcagtagttg ctgtgacagc aattattcct atggctgctt attcactagc aagaaaaatg
     8281 actcgtggga aagcatacgg attgatgtat ttatttttaa ttttaggaat ttttgttcct
     8341 ttccaagtaa ttatgattcc gattaccgtt atgatgagta aaattggttt agcaaatatg
     8401 tggggattaa tcttactcta tctcacttat gccgtaccac agacactatt tttatatgtt
     8461 ggttttatta aactaaatgt gcctatcagt ctggatgagg ctgctgaaat tgatggggct
     8521 agtcacttta caacttattt caaaattgtt ttcccaatgt taaaaccaat gcatgcgacg
     8581 actattattc ttaatgctct atggttttgg aatgatttca tgctaccatt attaatttta
     8641 aatcgtgatt ctaatatgtg gacactacca ttgtttcaat ataattatac gggacaatat
     8701 tttaacgact atggtccaag ttttgcttcc tatacagtag gaattgtcac gattacacta
     8761 gtttatcttg ctttccaaag aagtattata gctggaatga gcaatggagc agtgaaataa
     8821 ccaataaatt attctcatta taaaggagtt cataaactta tgattatatt tgacaatcac
     8881 acacaaacat ttcatttaca aaataaaaaa attagctatc tattaggaat cgaagaaaat
     8941 aattatttaa cgcatcttta ttttggaaaa aagattacgc actattctgg tgggtatcgc
     9001 tacccccgaa cagatcgttc cttctcaccc aacaatgcaa atgcgcaaga tcgtttatta
     9061 tctttagaca cattaccatt agaatttcca ggatatggac atggtgattt tagagaaccg
     9121 gcgcataata ttaaattagg aaacggtagt cgtgtaaatg attttcgtta tgatagctac
     9181 gaaattcaaa aaggaaagcc cagcttagcg ggattgccag ccttatatac ggaagatgat
     9241 gatgaagctg aaacgctgat tattcaattg aaagacgcga ttagtggatt gactttacag
     9301 ttgttctaca caatttatca aaatcacagt gtaattattc gttctacgca attagtaaat
     9361 aatagtgatg aaacagtgga gattaaccgc ttagctagtc aatcaattga ttttccaaat
     9421 cgtccactcg agttaattca tttaaatggt acctgggcaa gagaacgtca aatgactaga
     9481 gaaaaaattc atacagggat aaaagtatta gatagtaaac gcggatcaag cagccatcaa
     9541 caaaatccgt ttgttgcttt agtagatgcc aaaacagatg aatttcaagg agaggcatat
     9601 ggatttaatt tagtttatag cggtaatcac gaaacggtga ttcaaaaaga tccatttgac
     9661 caaacacggg tcattatggg aattaattca tttaattttg gttggcaact aaaaactggc
     9721 gactcatttc aaacgccaga agtcgtgatg gtttatagta atgaaggtct gaatacgtta
     9781 tcacagacgt atcatgaatt gtataatcac cgtttaattc gtggaaacta tcgtttaaaa
     9841 gaacgtccca cgttaatcaa caactgggaa gcaacgtatt ttgattttaa cgaagaaaaa
     9901 atcatgaata ttgtcgatga tgcgaagaac ttgggcattg aaatgtttgt tttagatgat
     9961 ggttggtttg gcggtcgtga aaatgacttc acttcattag gtgattgggt tgaaacagaa
    10021 ggcaaacttg cttgtggttt ggaaaattta gccaagcaag tgcatgataa cgggatgaaa
    10081 tttgggattt ggtttgaacc ggaaatgatt tctgaagata gtgaactatt tcgagcacat
    10141 ccagattggg cattgggtat tccaggtcgt gaccgctcaa ttagtcgaaa tcaatatgtt
    10201 cttgattttt caagacaaga tgttcgtgat aatatctatc aacaaatgac ggcgattttt
    10261 gatcgtgtac cgattgatta tgtgaagtgg gatatgaatc gaaatatgac agaagtctat
    10321 tctgtcttgt tggactcaac gatgcaaggt gaagtggctc atcgttatat gttagggtta
    10381 tatgaatttt tagaaaagtt aacaacgaat tatccaacta ttttatttga aagttgttcg
    10441 ggtggaggcg gtcgttttga tgcaggtttc ttgtattaca tgccacaaac ttggacgagc
    10501 gacaataccg atgccgtggc tcgtctgaaa attcaatatg gaaccagctt agtgtatcca
    10561 atttcaagta tgggtgcgca tgtttcagca gtcccaaatc atcaaacagg aagagaaacg
    10621 agtttaacta ttcgtggcaa tgctgcgatg gctggtgttt ttggttatga gctagatcta
    10681 acgcaattaa cttctgaaga aaaagcagaa attaaagaac aagttgcctt ttataaaaag
    10741 catcgccaac ttttgcaata tggaactttt tatcgcttgg aaagtccgtt tgaaggcaat
    10801 gatactgcat ggatgtttgt ctcaaaagac caaacagaag ccatggtctt ttatttccga
    10861 gtattagcag aagctgcgca tccattagtc acattgaaat tagcaggatt agcagaagaa
    10921 gcaacttatc aaatggaaga tgtaacattt gctggcgatg aattgatgaa tctcggtttt
    10981 tatattgact cagaactaca tggtgattat gcgacacaac gcttttattt gaaacagata
    11041 tagtagcttg aatttacaat ataagtgcaa caccaaaaga gactcattcc aaacgaagaa
    11101 aatatgtttt atttacacgc atttactaaa aagcagcctg atttgaattg ggaaaatgaa
    11161 gaagtacgtg aagaaatcta tgcaatgatt aactattggt tagataaagg actaggcgga
    11221 tttagaatcg atgcgatatt aaacatcaaa aaaaaactag agtatggcat ctttgaatct
    11281 gatggagaag atgggttagc cttcattggg ccctggattc ttaatcagtc gggcattgaa
    11341 gtgtggttaa aagaaatgag agagcggaca tttaaaccac ataatagtat gacggtagca
    11401 gaagccgatg ttcctaatga acgtttagat gaatatattg gtgaagatgg ctattattcg
    11461 atggtttttg attttagtta tacggatatt gatgtacctg aaactggtga atggtttaaa
    11521 gatagccaat ggacatggac ggatatgcgt accaatattt ttacgaatca attagttacg
    11581 caagataaag gttggggcgc cttatattta gaaaaccacg atcaaccacg ttcaattaat
    11641 aaatatattc cagaagaatg gatcaatgat tatagtaaaa aaatgttggc gacgcttttt
    11701 atgttactaa gaggtacccc ttttatttat caaggacaag aactaggaat gaccaacata
    11761 gaaatggcat cattagaaga ttttgatgat gtagctacgc attctcagta taaacgggca
    11821 ttagaatatg gattggcacc agagcaagca ttgaaagctg tcaataaacg aagtcgggat
    11881 aattctcgca cacctatgca atggaatacg caaaaaaatg ccagattctc aacttctgat
    11941 aatgtatggt taaaagtaaa tcctaattat ccagaactca atgcagaagc tcagttaacc
    12001 aatcaacagt cggtattcaa ttattatcat caattaatta aattaagaaa aaatagtgta
    12061 tacaaagacg tgctaatcta cggacaattt ctaccagtga aagataaaaa tgaacatatt
    12121 ttgctttatg aacgccaatt agaagataaa atcgtattag ttatcttaaa cgttacagca
    12181 acagaacaag aatattatgt agatgaacag taccaacaag tattaatcaa taattatgaa
    12241 gatgttttat tagatcaaag tcgaaaattg cgtttacgac cgtttgaaag tattgtatta
    12301 gctaattatg gaggacaatt atgaaaatta aaaacgaagc aatgctcatc acctatgcag
    12361 atagtttagg aaaaaacatg ggcgaattaa aacaagtctt agacaaacat ttacaaggtg
    12421 ttattggtgg tgtacatctg ttgccttttt ttccatcgac aggtgatcga ggctttgcgc
    12481 cgagtgatta tacgacagtt gatccagctc ttggaacatg ggaagatgtg gaagcattag
    12541 gtgaagatta ttatttgatg tttgatttta tgattaatca catttctcgt gaatcaaaat
    12601 ttttccaaga tttcaaaaaa aaccatgagc agtcaccata caaagaaatg tttatccgta
    12661 ttcatgaatt tttcccagaa aatcgaccaa cacaagaaga tattgattta atctacaagc
    12721 gtaaagacaa agcgccgttt caaacggtag aatttgcgga tggtacgaca gaagaggttt
    12781 ggaatacctt tggggaagaa caaattgatt tagatgtgac caaagaagtt gtgaaagaat
    12841 ttattcgaga aaccatcaaa gatatggcga accatggctg ttctttaatt cgattagatg
    12901 cgtttgctta tgcgattaaa aaattagata ccaatgattt cttcgtggaa ccagatattt
    12961 gggaactttt agacgaagtg cgtcaagaag cagcgaaata tgacgtcgaa ttattaccag
    13021 aaatccatga gcattattcc attcaaatga aaattgccaa tcatgattat tatatctatg
    13081 acttcgcctt gccaatggtc actctgtatt cactttatag tggaaaatca gaacgtttag
    13141 ccaattggtt gaaaatgagt ccgatgaagc agtttacaac attggatacg catgatggaa
    13201 ttggtgttgt ggacgctcgt gatttattaa cagatgaaga attggattac acctctgagg
    13261 aattgtataa agtcggggcg aatgtgaaga aggtctattc aagtgccaat tacaataatt
    13321 tagatattta tcaaattaac agcacctatt atagtgcatt aggcgataat gaccgtagct
    13381 atctgttagc acgtgcgatt caagtatttg cgccagggat tccacaaatt tattacgttg
    13441 ggttattagc aggaaaaaat gatattgaac tgttggaagc aacgaaagaa gggcgtaata
    13501 ttaatcgtca ttactatgat ttagccgaaa ttgaagaaga agtgcaacgg ccagtgattc
    13561 aacaattatt tgcactttta aaatttagaa atgaatctgc ggcgtttgat ttggatggaa
    13621 cgattgaagt agcaacgcca tcagaatcag aaatagtgat tacacgtaaa aataaaaacg
    13681 gtagtgatag tgcaacatta acggctaact tggatacgaa agaatttatc attgagtcta
    13741 aagatataaa aattttcact agtgttgcat taaaatttta acctattcca tagaacaaaa
    13801 aatcctttat actagcactt ggatgactta tccaagacca ataaaaagga ctcatacatg
    13861 gataagtata aaacaaatac agcatttaat aaatggtttt ctgccataaa attaggaaaa
    13921 ctttctgtca actcccaaaa atgtattttt gattacaatt cgtatcgtaa aaaactgtct
    13981 tttgaagctg tgctcaagct ctttctctac gcagttaatg aagaaaaaga aagtttgcgt
    14041 gatttgagta cagctcttat cgaccgatcg ctccaactag aaaccgatgt gtcatcgatt
    14101 agtcataccc aattgtctcg agcatttaat gcacttgaac ctaaagtgtt agaagaaatt
    14161 tttcaacaac tgttagaaaa agttcaacat caaatcaaac caaccaagcg aaatcatctg
    14221 tatctgattg attccagtac gttttcgctt agtttaaaac gtcataagtg ggcgactttc
    14281 cgtcaaacaa aatcaggtgt caagttacac ttaaactatt gttatatgga cgatactacg
    14341 atgtatccaa ctgattttac cttaacaaat gcccatgaac atgatctcaa tcaactacca
    14401 gtattggtga atcaaccaga ggcaacttac gtgtttgatc gtgggtatta ggactttgaa
    14461 aagatggatc agatgcattg ggatggctat ttcttcgtca ctcggattaa aaaaaacacc
    14521 aaagttcacg tgatagatac tctggaaaca tcgccagaaa cagaaattct acgagacgag
    14581 ctggttcgtt taggatctaa aacctatcta accgccaatt tccgactagt cactgttcaa
    14641 gataagaacg gacgtgtgtt tcaatttatc accaatcgaa tggacgtctc ttcaaaagaa
    14701 atctctgata tgtatcacgc tcgttggcaa atcgaattgt ttttcaagca catcaaacaa
    14761 cacatgacca ttaaaacctt cttttctcaa agtgaaaaag gcgtgcagaa tcaattgatt
    14821 ttaacgatga tttccgctct cctcacgttt ctcatcaaat tggagacgaa aacggaaaaa
    14881 tcagtgttcc aaatcaaacg attctttcgt tatttactgt ttcagccctt tgaatgttgt
    14941 ctagaaaaat taattcccac atgagaaaaa agaaatttgg ctcgttactt ttggttttca
    15001 gttgaataac agataaaaaa ttttctggaa aaagtcatcc tctgcgtcag cacagttttt
    15061 tttgacttat tttcagagga aatagttttc agaatattct aaaatgtttt atgcaacact
    15121 agtgatattt tttagaatta gatttctaat gtgcattttt tgagtattaa ggagcaagta
    15181 tacaaagatt tataaagctg attaaatttg aataaaaata tgc
//
LOCUS       DADVXK010000069        15221 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.070, whole genome shotgun sequence.
ACCESSION   DADVXK010000069 DADVXK010000000
VERSION     DADVXK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.070"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(797..1138)
                     /locus_tag="KB909_001973"
     CDS             complement(797..1138)
                     /locus_tag="KB909_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6837986.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1138..1368)
                     /locus_tag="KB909_001974"
     CDS             complement(1138..1368)
                     /locus_tag="KB909_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6837987.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1655..1993
                     /locus_tag="KB909_001975"
     CDS             1655..1993
                     /locus_tag="KB909_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837988.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(2198..2437)
                     /locus_tag="KB909_001976"
     CDS             complement(2198..2437)
                     /locus_tag="KB909_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6837989.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(2413..2760)
                     /locus_tag="KB909_001977"
     CDS             complement(2413..2760)
                     /locus_tag="KB909_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6837990.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(3492..4073)
                     /locus_tag="KB909_001978"
     CDS             complement(3492..4073)
                     /locus_tag="KB909_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6837991.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(4256..4882)
                     /locus_tag="KB909_001979"
     CDS             complement(4256..4882)
                     /locus_tag="KB909_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6837992.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4904..6235)
                     /locus_tag="KB909_001980"
     CDS             complement(4904..6235)
                     /locus_tag="KB909_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBB6837993.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(6390..6791)
                     /locus_tag="KB909_001981"
     CDS             complement(6390..6791)
                     /locus_tag="KB909_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6837994.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(6877..7083)
                     /locus_tag="KB909_001982"
     CDS             complement(6877..7083)
                     /locus_tag="KB909_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6837995.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(7178..8680)
                     /locus_tag="KB909_001983"
     CDS             complement(7178..8680)
                     /locus_tag="KB909_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBB6837996.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(8698..9153)
                     /gene="argR"
                     /locus_tag="KB909_001984"
     CDS             complement(8698..9153)
                     /gene="argR"
                     /locus_tag="KB909_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6837997.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(9251..9868)
                     /locus_tag="KB909_001985"
     CDS             complement(9251..9868)
                     /locus_tag="KB909_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBB6837998.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            10089..11462
                     /locus_tag="KB909_001986"
     CDS             10089..11462
                     /locus_tag="KB909_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6837999.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            11537..12649
                     /locus_tag="KB909_001987"
     CDS             11537..12649
                     /locus_tag="KB909_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBB6838000.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(12721..14358)
                     /locus_tag="KB909_001988"
     CDS             complement(12721..14358)
                     /locus_tag="KB909_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBB6838001.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(14526..15134)
                     /locus_tag="KB909_001989"
     CDS             complement(14526..15134)
                     /locus_tag="KB909_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6838002.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         4182 a         3132 c         2669 g         5238 t
ORIGIN      
        1 tattgacaaa aagtgactca aaataaaaaa aaccttacat tatactggaa tgaactgtat
       61 tgatagtgta cctaaaagct ctactgacat aagatcgtgt aatcggtaaa gtaattttat
      121 taattatacg ggatgtaatc aattagagaa taaactaatc ataaaaggta cttttacatt
      181 cataattgtc gctttgagat tctactttgg ttcactatct gacccaattg cacattttcg
      241 atcattacaa gtattggtgt cgttagaaca actaaataaa aactagcggt agatttttca
      301 gaatctatgc taatttctgt atggatgttc cagtgatggc aaatttctct tttcattgtt
      361 tttcttgtcg catgatatgc ctttttgtgt tattcagtta aactatagaa attctttcct
      421 agacagatct tgatcccaaa ttttacgttt ttgagcatcg atatagttta aaatgacatt
      481 actcatatct aaagagttta gattttttag gactaaaact gtcagttgtt ctttttcttc
      541 tttctgttaa agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa
      601 gttttgtgac acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat
      661 gctatatatt ctttagttta agatacggaa attaatgcca tcgaccacac tagtagaatg
      721 aacgacattt acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag
      781 agtttactta caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt
      841 gcaatggtaa gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt
      901 gtgtaataat tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta
      961 aattctttat agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt
     1021 cataacgaga gacgactagt cctggtcgtc ttttttgaat ttcttttcct acggagggat
     1081 caaaatcaat ccatacaata tcaccttttt taggaatata aattctttct tctgacacta
     1141 taaaatttct ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc
     1201 ctcttcccca ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc
     1261 agaatacaca acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa
     1321 agttaccact acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc
     1381 cttaataaaa gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct
     1441 agaaaattgt tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca
     1501 gttcattttt tctttaacta aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa
     1561 gctacccaaa tactatagct aaccccccgc taccttcaat tttgcagata aaacgctttg
     1621 ggagaaaatt tcaaagacaa caggccatcc tatcatgccc gattataaac aaaaagctgg
     1681 ctattccttt tgctctgaca aatttcaatt gggaaagttc acgaaactag caggtgaaga
     1741 agtttcaact gttcggatca aagaatgccc gcttcaaata gaaacattgg ttcaacgaat
     1801 ttcaactaga caagactttg ctattgtaga acgtgagatc gtagctattt ttgtagaaga
     1861 agggatttta catgatccaa ctcatatcaa tgtggataaa tggcaacctc ttatctataa
     1921 attcagagaa tatacaactg ccaaccagtc gttaactttg aattttagat tccaagaatt
     1981 caaagagtca taatgataaa catcgttagg tataaataaa aaagactcgc agcacgagta
     2041 aaaaacaaat agaagctata cattagaaag gtcgactgtg accctataga tgcagtatat
     2101 gcagcttatg agcatttctt ctgttctctt tgtttttggg atctgtgctg aagtcttttt
     2161 cgttttttgc cgctctttct ttgaaaaatc gattatgtta taccttctcc attactaatt
     2221 caggcatctg ctgagtaatg atttttcgcg caaaagaaat atctgttacc caaggttcga
     2281 tttgttcttc agtcaagaca agcggcattc ggtcatggat tggtgcgact gtgcggttag
     2341 gttcagtagt cattatgatt gattctgcca ttttttcatc ctgatggcta cgataaaaac
     2401 cgccaatata cactattttt tccttatttg aaaacataaa tttgtctttt tcttcattcc
     2461 actcattggg aaaacacaac gattttgcaa aaatggttga tgaaaggtct ttttttcttc
     2521 tactgtctct gcacgggcat taatcatcaa ttgtcctttt ttaaatccgg taaatcccca
     2581 cttcatgatt tccggagtga ggatgttttc ttcctctttt cttaacgtca caacaagatt
     2641 tgacggaaaa acttctccag ctgctaattc tgctgcctgc ttcggttgtt tcgtctgggc
     2701 ttctcgataa taattctgaa ggagctctga ctctagatca aaaaaataac gaccacacat
     2761 cctaatccct cccaatcttt ttttctatca tacactgcaa caagaagttc gcaccaacaa
     2821 aacgctttca atttttgtag aactaaaaaa gttgtgacaa gtgacaaact ctccagtgaa
     2881 tggtattctc ctgccaactc ctcggtcaca agtcacaata ttcaacaaac atgagaagct
     2941 gctttttgaa attgttcctt gtgactcgga gtgaaacggc aggcttacga cctctgggta
     3001 aacggtgttc aaaagccagt ttctcggtat taagccaaat ttatgcaaaa atgtagaaag
     3061 ctattttcac aaaatttttc ttaatactcg aaactaagcg actttttcac aacctcttcc
     3121 ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga
     3181 gcagctattt ttatttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
     3241 tccactaaac ggtgttcaat cagctaacct tcggtattag ctcaaaaaac ggcaaaatat
     3301 gaggaactat tttgccgttt gtttctctaa tactcaggtc aaagcgctga tttcacaacc
     3361 tctaatacac ggtgttccag aagtagcttc ttcgaaaaat aagccgaaat ttcacaaaaa
     3421 tttgagaagc aattttcgta aattccttct tatttcttga agctgaccac ttctgtcaca
     3481 acctctaatt attaaagaac cttttgcgaa gttaacaatc tttctttgat caattgaaaa
     3541 ttctgcctaa gtagtgatag atcctgtgtg actttcaaca ataagatact tccctggatt
     3601 tcagcaatca acgctttggc ttgacggtct gcttcttcat cggacagttt ttcttcagaa
     3661 agtgccagga tattttgttt cgtatacttg acccattgat tgactaattc tagtagcaac
     3721 agacggtatt cttcatccac tgtactcaac tcaataatca aattacctac aggacagcca
     3781 tgataagtga tctgtgtctc atgatcagcg aaaatccagt ccaacatttc ttctaatgct
     3841 tcttctggct gttttccagc atttaagatg tcttcgaaca attctgtctg ccatacgtcc
     3901 atatgcgcat ggatcaccgc tagacaaact tctttttttg aagaaaagta ataataaaat
     3961 tgaccttttc ctgtatcaga agctgctaga atatctcgga ttgacgtttc atgatagcct
     4021 tttttataaa taagatcttt ggtcgcttcc aagatctttt cctttgtttt caatgatatt
     4081 ctcctttttc atttctcata gtcctatatt atacagtaaa ttcatcattt tttcttctta
     4141 atcgtttaaa aaagactgtg ccaaattatc tgacacagcc ctcactataa aactgttctc
     4201 atatagctag atgttcattg attcaagaac tgcgaggaca aaagcaattc ctatcttatg
     4261 atagttgctc taatacttcc tctgttgtca tcacttgatc tgcaataaag ccaaagttcg
     4321 tcaacgctgc atccattgct tcttggccag gagcaccaat tgcatctgtc gctaccacaa
     4381 cattgaatcc actctctacc aattcacgca tatgggaatc gctacacaag tttccgttca
     4441 ttccaccaag aattactgtg tcgattccat tttttctcaa ttggagcgcc aaatcattgc
     4501 tttctggtcc aaagatttta tgaggagagc tgatgatcgt attttcatcc aaataaggtt
     4561 tcaattcttc gataaaatcg gctcctgaac cttcttccac tgattcatat tgactttttc
     4621 tagcaaacat ctgctgctca agcatcatat gttctcctgc accgccaaat tgccatttat
     4681 ggtcatgtgg gtaaaaataa tgaggagaaa taaagagttt gtatcctttt tcttttgctt
     4741 gttttaccat ttcaatcata ttttcgatcg tattgtattt ttctaagata tcttttgtca
     4801 aaccaaagcc accgcctgct ggtttcaaga actcgacttg cgggtcagtg agaactactg
     4861 ctgtattttt attattgaac atggtggatt ctccattcgt tatttatttt aatacatcat
     4921 ttagagcttc actcattgtc ggatgagaat agatttgatc tctcaataac gtataaggaa
     4981 gttttccatt catagctagc gaaatcaagt tgatgacttc atgagaatct tccgcataga
     5041 tacttgcccc tagaatcaag tcagtttcag ggtcgactaa aactttgaat acacctttag
     5101 gatcttctaa tacttgtgct ttagggacac cgcttgtcat atacttgaat aatttgtaat
     5161 tgacgccttg tgctttggct tgtttttctg ttaaacctac attggataaa gtcggagtga
     5221 taaatacact gtaaggcaca gctttccggt tattcgttgt tcgtttattc tcgcccttca
     5281 actgatccat aatgattcga taatcatcta gagagatata agtgaactgc aatccgcctt
     5341 tgacgtctcc aatcgcccaa atgttgtctg catctgtacg aaggtattca tccacagcga
     5401 ttgctccgcg atctgttagt ttaacatctg tattttctaa tccaagtgat gctgtacttg
     5461 gttttcttcc agttgcagcc aaaacttttg acgcttggat tgttacttct tggccatctt
     5521 ctgtaaaggt gacggcagct gttgattctt ggtctgctac ttgatctaca gatacaccta
     5581 gatggaattc gattcccgca tttgtcatgt cttctaaaat catttgcgcg atatcttcat
     5641 cttcacgtgg aagaaattca gaatgggcat caagaacgac aactttagat ccgtattcat
     5701 tgaacattga tgcaaattcc aagccaatat atccagcccc gatgatcact aatttttccg
     5761 gtaattgttc ctgatccatc gcttgcgtag aatcaatcaa gtagcgactt gtattcaatc
     5821 ctttgattgg taaaatgatt ggttcagaac cagtattgat gaaaatccgt tcgccttcaa
     5881 caatcacttt ttcaccatta ttcgtcactt cgatttgatg gttagaaaga aaacgtgctg
     5941 taccgtccat cactgtccca gttgcctcat cgctgatcat atgataattt ttggcgcgaa
     6001 gcatgcccgt caatttttct ttccgagcaa cagcctctgt aaagtcgatt cctctttctc
     6061 cattgaaaat caatgattta gaaggaatac agccgatgtt gatacatgtt ccgccataca
     6121 tacgtgttga cttttcaacg actaaaaccg attcaccttt tgaagctaac gccttcgcta
     6181 aagtcttacc gccctttcca aaaccgatca caatattttg atatttttcc atcatttttc
     6241 cctcgcttct tttttaccta ccgattggta caaaaatatg ataaccgata attgtctatt
     6301 ctccaaatca tctgctttat ttgtcaaaaa aaaccagaca aaaagcggtc ctttcacgtt
     6361 tttagtctgg ttcgatttcc tttattcttc taaacaatcg ttacttctac atcgatattt
     6421 cctctagttg ctttggagta agggcagaat tcatgcgcat cttctgcaat tttttgggct
     6481 tcttcttcgc tgatgccatc gatatgcact tctaatacta caccgatctg atagccgcca
     6541 tcatctaaat tataaagaga gacacgtgct tttactgtgg actctgctgt cattcctgct
     6601 tctttgatca tatgttgtac cgccccattg aaacaagaag cataacctgc tgcaaataat
     6661 tgttctggat ttgttccttc tgcatggatt cctggaggag tgattttcat atgcatcgag
     6721 ccatttggtg cctcgacttc tccattgcgc ccgccatggt tgatcattgc tgtttcgtat
     6781 gcttttttca ttgtactgct cctttcgatt gaccatttgc tacttggcta taattatagt
     6841 gtatgacaag taaggcgctt tctacaaaaa ttctgcttat tcgaatacca gaatgccgtc
     6901 ttctactatt tttccaaaaa acaaaaaaat actactcgtg aacaacagcg tcatatttgt
     6961 tccaaaataa atagcaatct tttctacata atcttttata tgattgattt taagatacat
     7021 atataccaga aagttgaccc cataaaccaa tactgttaaa aaaataacca tattcgttac
     7081 cattttttcc tccttttgct ggtctcccta ccagcactcg atttaaccat accacttttt
     7141 ttgccgtcca agcaactagc ctttcaaaaa gactggttta ttctgctgtt aatgattcaa
     7201 gatcagaaaa atgtccgaat aattttgcta attttactaa cgccaacttg ttctttccga
     7261 attcatcatt ttctatctgt aatactagta acggctcatg taagcttaaa cggatcaaaa
     7321 accagccgtt tccgtatggc tcttctagat catatcgaat accttcttca ttttccgggt
     7381 cgaagttcat ccctttttct tcttccaaca gtcgcttcat ttcttctaat atcttgtttc
     7441 cttgttcgcg tggttcatcg ctgaacaatt ttaatcggat ttcttgtact tctacgggct
     7501 gtttcaactc tttgatttgt tcatctaatg tgataccttt tctttttaat tctggcaaaa
     7561 gcatcaggat ctttgcgatg acatatgcac catcatccag aaaatagttt tccttgaatg
     7621 cagcgtgtcc gcttgtttcg atggctagct gtgtatcttt cccaagacgg ttaagttcta
     7681 atgctttatt gattacattt cgatagccgg aaatataacg aacttggatg cctccttttt
     7741 cttcaatgaa tctttgtaga tgagaagaag taggggaatt cgtcacgatt cttgttcctg
     7801 gatgctcttt taatacgatt gtacttaata ctgcgatcaa attatttcga ttgatcactg
     7861 ttccagaagc actgacaact gcagaacgat ccacatctgt atcgaaaatg atcccaagat
     7921 ctgcttcatt tgctaaaaca gcctgcttga tactttccat cgcttcttta ttatcaggat
     7981 ttgggatatg attaggaaat cggccatctg gttccaaaaa ttgggaacct gttgaatccg
     8041 cacctaagct attcaatact ttttcagcaa agaatccacc agcaccattt ccggcatcaa
     8101 caatgatttt ccaaccattt agtggtttgc tttctagtgt tccaatcccc tttttaattt
     8161 ttgtgactaa atcttgcgca taaggtgtca aaaggtctgc tttttctacg cttccagttt
     8221 gttcgctttt tattttttgc tgctgtgata ggataaaagc aatatcttct ttttctgctc
     8281 ctccttctga ggtaaagaat tttattccat tataataata gggaagatgg ctagcagtca
     8341 gcataaccgc agcatcgcac gagaactgtt caaattgagt ggacataaac atagcaggcg
     8401 tagtagctaa ttcgaaatcg atgacatgta tcccttgttc tttcagactt tggatcaacg
     8461 cctctttcag tgctggtccg cttatcctac tgtcatgacc aatcccaatc gtccattttt
     8521 tatttggatc ggttgatttc ttctttttct ttatccagtt tgctagtccc cagccgatct
     8581 tttttaccat gtctgtcgtc aagtttactt catatccttc aactggtaat gcgattcctc
     8641 gaatatccga tccattttgc agcgctttca tatctttcat ataaaagtcc tcctcattta
     8701 ttccctcatt ttttccagct tttctgcaaa tcgctgtgct tcttcttctg agcggcaaat
     8761 aataatgaat gtatctacac cggccatcgt tccgacaact tcagggtaag ccacttcatc
     8821 tagccaattc gttaccacat cggcaccatt tcgttcagtc aatacgataa ccatgaactg
     8881 aacagactgg atacgcaaaa cctcgcgtct aattgctgta cgcaaacgtt cttcatttaa
     8941 agaaacagat ggctggttaa ataatgtata gcgtactatt ttgttttcat tttgactttt
     9001 tactaacttc atttctcgaa tgtctcgaga aatcgttgct tgagtcacat cggcgcctgc
     9061 ttcatgcagc cgcgcaagca gctcttcctg tgtcccaata ggttgttctg taatgatctg
     9121 gcggatcagt gcttgtcgct gtttcttttt catattagac acctctcaat gttgattata
     9181 gcaaaagata agtaatattt cttcatattt tggtattttt tacttttatt ttttgttttc
     9241 attcaggttg ctaacctttt tctattttaa cacgcaaaat cgtcttcatt ttttcaggtg
     9301 ctgattttct tggatcgctg atgtaaatct ctttgtgttc tttagaagct ctttcatagc
     9361 cttcttttgc gatgaatgct tctaatttct caaacgttgc tggttcttcg gcatagggcc
     9421 cgacgtgtaa gatttgggca caaagacctt cttccatctt tttgaatact acttgttctt
     9481 tcaagtcttc cggaagtttg ctagaacgct gaatggcttc ttgtgctatc gcttctgtaa
     9541 caaagtcagg ctgtcggatc atcaattgat aagaaaaatg ttcttttttc atcactggtt
     9601 catgcaaata cttttcttgc agtccccatt gtccttccag tggatagaca gtatacatct
     9661 gataatcagg aatcagccaa ttttttttag gcgacatgcg tattgcatag ctgactgcat
     9721 atagacaggc tactcttcgt ttaaagtctt cctgattcgg gtcgccgatc cctctgatgc
     9781 taaagaatga ttttttagga acctctagta tttgcgggct ttttttcata ctatagctct
     9841 tgtctttacg ccattcaatt ttttccattt ttcttcctcc gcgaaattcc atttagttat
     9901 ttattatcat acctcttttt gagtgacttg gctaatcgtg ttgacactat ttttcagttt
     9961 gtgctagaat aagtgaagta aataaatcgt acagataaca cgtttcggcg tgtcgagaga
    10021 gaggcggttt ctatttttat aatagaaatc actctctttt tttacgaaat tttttagagg
    10081 tgatgtaaat gacaaaacaa aaacagctgc ttttagtacc tgcagtaatt gcaacaggga
    10141 tgatgtcttt tgcgggcgta ttgatcgaga cggccatgaa tgtaactttc ccaactctta
    10201 tcagacagtt tgatttaacg actgcacaag tccaatgggt aacaacgatt tatcttttga
    10261 tgatttcgat cattgttccg ctgtctactt atttgaatcg caattttagt ctcaaaaaac
    10321 tctttttagc ttcaaatctg cttttcttgg caggtataat gatcgatttc ttctctccta
    10381 ccttcatggt cctattgttt ggtcgattgc tccaaggtgc agcgacaggt atcgctcttc
    10441 cgttgatgtt ccatattatc ttgacatttg cccccctcaa tcgacgaggc gcgatgatgg
    10501 gtgtcggtac tttgacaacg gccattgctc cagcaattgg ccccacttat ggaggcatta
    10561 tgacttcaca ttttacatgg aatcatatct tcctgtttct tgtgcccgtt ttgtttcttt
    10621 ctttgattat cggctggttt gctattcccg agatggcagt acaaaaaagt ggttatttgg
    10681 attggataag cgttttagga atttgtcttt tgtttagtgg aagtctaaca tttttgagta
    10741 cgttgggaac agtttccagc tggattgctt taatcatcgg cggtattggc tggttccttt
    10801 tttactatcg aagtaaaaaa gtggagcatc cactgatccg actgtctatt ctttcaaata
    10861 aaacattccg cttgtttttg attggcttct tagtttatca gtttttatta cttggtgtat
    10921 cttttgtctt gccgaatttc cttcagatcg ttcaaggaag tagtcctttt gtcgctggat
    10981 tagcgatgct tcccggcgca gcggttggtg ctttgctttc tcctttttcc gggaaaatgc
    11041 tggatcaata tggtccgaag aagccaattt ttgctgggct gattctttct ttgattggtt
    11101 ggctagcatt attcctactc ataggacacg cttcagtggg tgtattgatt gcttgtcatg
    11161 tgttttatat gatcggtatc ggattatctt acagcaatat gatgaccacc ggaatgaatg
    11221 cactgaatga agaactacaa ggagacggga acgcaatgtt caataccttg cagcagtttt
    11281 ctggcgctgt ggctacttca ttagtagcgg tcattatcaa ttacgtccag catcatactt
    11341 cccataacta tgaagtgtct actacattag gatcaaaagc agcattaggc gtcttgttgc
    11401 tgttgcttct cgtaagcttt gctcgattcg cctattatct gttctttgct aaaaaagcgt
    11461 agattccata tacggcaggt gttgcatctg ccgttttttt gtgtgaaaat ggttgtttgt
    11521 aaaaggaggc ttttttatgg aaaaaattgc cattatcggt ggcgggatca ttggtatgac
    11581 cctagccagt tacttagata catcaaaatt caatgttgct ttatttgatg aagggacagg
    11641 acaggcaact aaagctagcg ctgggattat ctccccttgg ttgtcgaaac gcagaaacaa
    11701 acaatggtat cgtctggcta aagacggcgc tgcttttttc cctaaactta taaaagattt
    11761 ccaacttgat caaacgattt acgcacaatc agggacactt ttgcttcgac ctgaaaaaga
    11821 tttagctgaa ttggctgttc ttgccgagaa acgaaaagaa gaagcgccag aaattggaaa
    11881 catcgaatgg ctttcacctg aacagacatc tcaagcactt ccgttattga aaccagcagt
    11941 ttcactgcgt atcagtggtg gtggtcgtct ggatggaaaa gcatatttag aacatcttgg
    12001 tcagcgttta gcacaaaaac aaatggagca gatccaggca aaagtcactt tgcataagaa
    12061 gagcgattct tggctcatca agggaccgtt tggagaatac acagctgatc gtgtaatttt
    12121 gacacctggc ccggcactta agcctttatt acaagaatta ggctatgctg cagatatacg
    12181 tccgcaaaaa gggcagctct tagcatttca gacatcttat aagatgagtc aagactggcc
    12241 tgttgctatg cttgacggag aagctgattt cattcctttc atggatggaa agatcctttt
    12301 aggtgctacc catgaaaacg atcaaggctg ggatttggct cctactagcg aagcttataa
    12361 gggattgact aagagtacag aacagttctt gactgatcca gatcagataa aaaactggcc
    12421 atacgagttc cgtgtaggta cccgtgctta tacgtcagat ttttccccat ttttcggcgt
    12481 actgccagat gatccaagct tactggctgc tagcggtcta ggctcttctg gcttgaccac
    12541 aggtccttat atcggctatc tattagccaa cttcttaaat actggtcatt ggcctacgga
    12601 agattatcaa aaggacatct ccacctatat tacgaaaaat ccatcataga aaaacagctt
    12661 tttcaagtaa ggatcccgag cgatattgcg catggattac ttcttgaaaa agctgttatt
    12721 ttagttcaat ttctgaatca aattctccaa actttctttt gcttcatctg gcaagagatc
    12781 ttttcctatc tgagcttcaa tgaatcgtaa acgaatatca agtcgttgtt tcaccagatt
    12841 tttataggac gtatcctcaa aagaaacagg aaaatctggt ataggtaaat agtggatgtc
    12901 ttcaaatgga ccaaacgact tgaattctgc cgtttgttgc acgattcttt caacgattga
    12961 caatgtcgtt tcaggtttga tttttttatc atcgaaatat ccagtattca ggacatagca
    13021 ggctgtttgc tgtttcaaaa acaactctcg aaaagcttga tagtcttccc taagaggata
    13081 gacacggaaa ggattagcaa atggttcaat gactagctca tctagctgtc tttttgtagt
    13141 gatattttcc gcgtctgatc gttttgttgc taatgttgca ccaaaagacg ctgctaaaac
    13201 tgggtcattg atcttgataa ttggcggaag cgaatcatct ttcatgatcc aaaaaacagc
    13261 atcgatcttt tcgctaagat gatcgactcg gtcgggtgtc gcataacgtg atttgactgt
    13321 ccgcccattt ccgtttcgta tatctcctgt tactaggact ttttctcctt tacttgtaca
    13381 tgtcacgccc acattctgac aagtaaggaa agaagaaatg gccggatcat cagacggata
    13441 gtcttgtgtt ttatcaaagt aagaaggttc caaggcagta gcaaaaccat tttttcgaga
    13501 aataacgaaa gcatcgtcat gcaagatcga aacagagtga ccttccgtat gttttgctaa
    13561 ggtaatcgtt gattttccag aaccggacaa cccaaataca gccatcgtat aggtctggtc
    13621 attactagca tattgtttca tcccaccgtg gcaggcaata aagccattgc gatttcccaa
    13681 tgcccaagca agcgtcaaag tcgctttttt taattctcca aagtaacgta atcctagcac
    13741 agccgctgta ttatggagag catcaaacaa aatgagtcca tttggaaatg tttcatgtgt
    13801 ccattcggga tcacaaaaga tataaagatc tccctcatca aaggaaacag acttttgata
    13861 agtctctaag atcttcgaat tcgctggctg aaaattcagc aaataagaat acaaattgtt
    13921 ctcaaatcct tctggaatca gcaaatgact ttgcacagaa aattcttcag ataggccaac
    13981 gattactttt gtatggtaaa actggcgctt gcgactttga tacacagctt ctcttaaaat
    14041 tttctcgtat ttgctttgtt ccttgtctaa gtcctcaaag atccgccgag cacttgctgt
    14101 tcttcccaca atgcttccat cattgaatac tagtgtccta acatcagctg gtaaatctag
    14161 ttcttcagca tgtgagattg ttaaatctgt gatgatcgtt cctggactcc cttttgctag
    14221 ttgataagct gtcttcctat caaaaacttc atgaacatta ttaccgtaaa atgtcgtttc
    14281 tacaatcgat cgaatactgg ataacagtgg atttccactt gtgatttcgt ttaattcgag
    14341 actctctttt gtactcatgg ctcctcctca ttccctaaac aaaaaaacgt tttctttatt
    14401 atacattatt cgagttttta tttgtactgc tgcgctgtgg gaagcaaacg agttattttt
    14461 cacacaaaaa aaccgagaac ttgaataaac aagtttctcg gtttcatcat tttcctttta
    14521 tcggcttagt accagccgtt tgctaaccag aatgttttag cagcatccca tgaaccataa
    14581 cgagatgtta catattgttc tgctacacgt tcttgattgg cagctgaata gtcgccgttt
    14641 aagtatgaag catctaattg ataacggccg atgtaacgtc cgttagtagc tgtgtatgaa
    14701 ccgcctgatt ctttttgtgc gatccattct tttgcagagc ttgaagttgg cgctgttgca
    14761 gcagctgggg cagcaggagc tacttcaact gtttcaacag gtgcaacgta tgtatgttct
    14821 tgcgttgctg tttcagttgt agatgctgta ttttctgttg ttttgttttc tgttgttgct
    14881 gaagaatcat ttgaagttgg gattgttaat tgttcaccaa cataaatgcg gttgatgttt
    14941 gcgatcgaat ttttttcagc aattgcatcg atcattgagt tgtctcctgc aaatttttgt
    15001 gagatcttag ataatgaatc acctgatttt actgtataaa cttcatcagc gtgagcattt
    15061 gtagttccta caaacattgc agtagcacca gcagcaaaag ttgtacctaa aacaattttc
    15121 ttaaatgaat tcatattaaa ctcctttttt tctccgtttt ttattctttc gacgctatta
    15181 actttatcat ttagaaatat ttcataggta aaagaaacat g
//
LOCUS       DADVXK010000070        14597 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.071, whole genome shotgun sequence.
ACCESSION   DADVXK010000070 DADVXK010000000
VERSION     DADVXK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.071"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(170..316)
                     /locus_tag="KB909_001990"
                     /pseudo
     CDS             complement(170..316)
                     /locus_tag="KB909_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            555..1247
                     /locus_tag="KB909_001991"
     CDS             555..1247
                     /locus_tag="KB909_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6838003.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLTLENDKNQLTIEKT
                     NLENQLSGKNAELQGKQNEINAKIDEINQKIAEINQLNTDWNNRLQTEQNKFNDAQNT
                     VNSLNQQINQLSNEKNTIKNQLQSTEQKLEKAQSENSNLNNYIEKLEKAKSDVEDTAN
                     RSQEIVTEHTGK"
     gene            complement(1529..1601)
                     /locus_tag="KB909_001992"
     tRNA            complement(1529..1601)
                     /locus_tag="KB909_001992"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1566..1568),aa:Lys,seq:ctt)
     gene            1982..2551
                     /locus_tag="KB909_001993"
     CDS             1982..2551
                     /locus_tag="KB909_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBB6838004.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2538..3398
                     /locus_tag="KB909_001994"
     CDS             2538..3398
                     /locus_tag="KB909_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6838005.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3588..4292
                     /locus_tag="KB909_001995"
     CDS             3588..4292
                     /locus_tag="KB909_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838006.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4297..6132
                     /gene="walK"
                     /locus_tag="KB909_001996"
     CDS             4297..6132
                     /gene="walK"
                     /locus_tag="KB909_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBB6838007.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6129..7445
                     /locus_tag="KB909_001997"
     CDS             6129..7445
                     /locus_tag="KB909_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838008.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7446..8315
                     /locus_tag="KB909_001998"
     CDS             7446..8315
                     /locus_tag="KB909_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBB6838009.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8370..9179
                     /locus_tag="KB909_001999"
     CDS             8370..9179
                     /locus_tag="KB909_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6838010.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9282..9911)
                     /locus_tag="KB909_002000"
     CDS             complement(9282..9911)
                     /locus_tag="KB909_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBB6838011.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10081..11373
                     /locus_tag="KB909_002001"
     CDS             10081..11373
                     /locus_tag="KB909_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6838012.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11449..12111)
                     /locus_tag="KB909_002002"
     CDS             complement(11449..12111)
                     /locus_tag="KB909_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6838013.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12336..12620
                     /gene="groES"
                     /locus_tag="KB909_002003"
     CDS             12336..12620
                     /gene="groES"
                     /locus_tag="KB909_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBB6838014.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12671..14296
                     /gene="groL"
                     /locus_tag="KB909_002004"
     CDS             12671..14296
                     /gene="groL"
                     /locus_tag="KB909_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBB6838015.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4947 a         2464 c         3077 g         4109 t
ORIGIN      
        1 caaaaaagtc tagttttttc aataatattt atgtaataat aaattagcca ccacaacaaa
       61 gaatgaaatc cattattatc tagtctagtc cattcttttt gtttgcagta tttgtgatgg
      121 ctttccgtac ccttagctca gttggtcaga gcagacggct cataaccgtc cggtcgtact
      181 tctcgtaatc caggaaggcc gtcagctccg tccgcagtag cgtgtttacg gccagctcca
      241 gatgggagcg gaataactcg ttcaaatcac ctttggtggc tagagtctgc aggagttctg
      301 taataaaatc gttcataggg aagtcctctt ttctgtgaat gggtgtggta actttattct
      361 acagaaggga cttccttttt tctatttaca caaaatattt tatactctca aatgtttgta
      421 tgcagttaca tctgacttta ttcgaattaa ggaaaagatt tataaaaata aaataaaaaa
      481 atatatattt aaattgactt attgtgaaat cattaactat aattagttca gtttatgtta
      541 aggagaatga tgatatgaat aagaaaattg tagtaagtgg attaattata ggtggattag
      601 tgttagcagg gatcgcaggg aaaaactttg ccgatgacat tttgttatgg ggtggagaag
      661 ataatattga acaaatcaat cataatttgg agtcattaga taaagcacta gaaaataaag
      721 agcaaaatat tagtagttta aattcacgat tatcttcaaa taatcaagaa cttgagcaag
      781 caaaggctaa cgttgaagaa tataaacaaa aagtgttgac tttggaaaat gataaaaatc
      841 aattaactat agagaaaaca aatttagaga atcaattatc aggaaaaaat gctgaattgc
      901 aaggtaaaca aaatgaaatc aatgctaaaa ttgatgaaat aaatcaaaaa atagctgaaa
      961 taaatcaatt aaacactgat tggaataatc gtttacaaac agaacaaaat aaatttaatg
     1021 atgctcaaaa tactgttaat agtttaaatc aacaaattaa tcaattgtca aatgaaaaaa
     1081 atactattaa aaaccaattg caaagtactg aacaaaaact agaaaaagcg caatcagaaa
     1141 acagtaattt gaataattat attgaaaaac tggaaaaagc caaaagcgat gtagaagaca
     1201 cagcaaacag atcacaagaa atcgtgactg aacatacagg aaaatagatg cattttttag
     1261 tttaaatttc tttaacaaaa tagtattttg ttgctaaata atttttattt gaatattcta
     1321 caatgatatc tcccctcaaa atggagggga agtacatact gtgataatct acaggtttat
     1381 tgactgatta ggatgttatt aaaaaataaa atactaaaat gcatacccga atttcatacc
     1441 cgaaaaataa aaaatgccac cacgtacact cttttcgaaa ctacctaagt agccaagaat
     1501 gtactggtga cgtgggtttg gcacccaatg ggccgtgagg ggctcgaacc cgcgacccgc
     1561 tgattaagag tcagctgctc taccaactga gctaacggcc cgtacaaaaa gtacttaata
     1621 atagtagcac taagaatttt aaaatgcaag actacattta aagaaaatca gaaaaatctt
     1681 tacttcctta taggaaatca ttcatagatt attcacattt gctcgctatt atataagcat
     1741 accaacaaac aaagttcttg caagagaaca aaccctaaca cttttttcat tttttactcc
     1801 tttcccgccg tctccccggc gggtctcctg ttcttaacga taaaagacaa gaaggcttag
     1861 ccttcttgtt ttttgttttc atggaatccc gctaatcaaa tcacctagtt aaagcaacta
     1921 gattgaatgt ttatcataag tctgatatca tgtttatgaa atgaaaaaag gagcggttat
     1981 gatggaaaaa atgcgtcagc aattaatgga gtgggggaag gaactagaaa cattccgtct
     2041 gcctcactgg gaagaactcc ctgacttaga actttatatg gaccaagtca gaacgttagt
     2101 tgatcgttat ctttcacctg tgatacaagg agaaaagcat ccattgctta cctcttctat
     2161 ggtaaacaat tacgttaaac taggtttgat accagcacca gttaaaaaaa gatataacaa
     2221 agaacacgta gcatttttac ttgcaatcac tacgttgaaa caagtattga ctattcctga
     2281 aatcaaagaa gggatattgt tccaaggaaa aacagtagga attcgtgaag cctataatct
     2341 attttgcgat gaacaagaag cagctgtgtg gatggtcagc caattagcac aaggtaaatc
     2401 tcatccgcaa aaattcgacc aggcaacccc tgtagaatat attgctgtaa gagcggcaac
     2461 tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt gttctagaaa ccgaatattt
     2521 aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat tttagtagat tcaggtacgg
     2581 atgtgccaga agaattgata aaaaaatacg agatgtatat gatcccattg aaaattattt
     2641 ataaagatca ggtatataca gataaaattg acattacctc tgaagagatc tatcaacgtt
     2701 tgccagagga aatccctggt acatctttgc cggatggtga gtcgatcaca gaaatctttg
     2761 agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt aacaatttcc agtggattga
     2821 gcgggacata taatgtggtt cgtttaattg cacaacagca agaagaattg gaagcatatg
     2881 tactagatac gaaaaatatt ggtattggtg caggtttttc tgcgatccaa gcagcaaaat
     2941 ggctggaaga aggagtagaa tgggatcaac tgatcagtaa tctgaatgag ttagtcgaaa
     3001 gaacaaaagt tttctttaat gttgcgacat tggaatatct tcaaaaaggt ggacggatcg
     3061 gtttagttgc ttctattgta ggaaccgctt taaagcttaa cccaatcatc tcatgtaatg
     3121 aagaagggat ttattacaca gtaggaaaag ctaggggacg taaaaaaagt ttggataaaa
     3181 cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt cttcaactta gctgttgccc
     3241 atggggatgc gaaagaagaa gcaattgaaa tggaagcgag acttaaaaga gagttcccac
     3301 aagcaaacca aatctacttt ggccagattt ctccggcatt agtagtccac actggtccgg
     3361 gattattggg tgtcggtgta caagttttag aaggataaat caaaaaaagg aaacactgag
     3421 gtgaaaatca gtgttttcct tttttattga agttagaaca aaaaataata aagtattttg
     3481 cactttcatt ttaattttct cttttgtttt ataggcaaag atgaaacaaa agcagaaata
     3541 cggtataatg agaaggtatg acaataatat ataagaggtg gctctttatg aaaaaagttt
     3601 tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa attcaattta gccaaagaag
     3661 gctatgatgt ttatactgca tatgatgggg aagaagcctt ggaaaaagtt gctgaggtag
     3721 aacctgattt gattttactt gatttgatgc tacctaaaat ggacggctta gaagttgctc
     3781 gtgaggtacg caaaacttat gatatgccga tcattatggt aacagccaaa gattctgaaa
     3841 ttgataaagt cctaggctta gagttaggcg ccgatgatta cgtgaccaag ccattttcca
     3901 accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg cggtgccacg gctgcgaagg
     3961 aaccagaaga ggcagcacct gcggaattga cgattggtga tttgacgatc catccagaag
     4021 cttacatggt gacgaaacga ggagaaacaa tcgagttaac acatcgtgaa ttcgaactac
     4081 tcttttactt ggcgaagcac cttggacaag tgatgacaag agaacattta ttacaaacgg
     4141 tttggggtta tgattatttt ggagatgtac gaacagtgga tgtaactgta cgtcgtttgc
     4201 gtgaaaagat cgaagataat ccaagccatc caaattattt agtgacacgt cgtggtgtcg
     4261 gttactattt gcgtaaccca gaacaggagt aattggatga aaagaaaagt ccgctttttt
     4321 cgatcagtca attttaagat cgctattacc tttattctga ttttattgat ctcgatcgaa
     4381 attattggtg cctactttat acgtggttta gaacgttcca cgatcaatac atttattaaa
     4441 gatatgaatc aaacggtgga atcattagca acaacaatca gcccggaatt gaatcgaaaa
     4501 gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa gatttattga aaacagtgcg
     4561 actagcgata tcatcgaaat acgggtcgtt gacgaaaaag ggatcatccg aggaacaacc
     4621 gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt atgttgatat caatgatttc
     4681 acgactaaac gttatgttgc tttagataac gacgataaac gggtgaatat caatgttcaa
     4741 ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc tttacgtcaa aagtaatatc
     4801 gaacaaaaat attcggaaat caataacaca gcagtcattt tctttactgc ctcactaatt
     4861 gcggcattta tttcaatgat cgtatctgtt ttagttgctc gttcgattac acagccgatc
     4921 ggtgaaatga gagaacaagc cattcgaatc gctagaggag actacagtcg gaaagtcaaa
     4981 gtgcatggac aagatgaact tggacagctg gctgatacct tcaatcagtt agctgaacgt
     5041 attgaagaag ctcaagatac aatggaagct gaacgcaatc gtttggatag cgtgctatcc
     5101 catatgacag acggcgtcat tgcgacagat cgcaggggta aagtcattac gatcaatgat
     5161 atggctgttt ccttgctaga tatcaaaaac gaggaagcaa tcggacaatc gattttgaca
     5221 cttttagata tcgaagaaga atatacgttg cggaaattat tagaagatcc aaacgaaatg
     5281 gtacttgacc gttcaaccag tacattggaa agtgatcaga tgatcttgcg agtagacttt
     5341 tctatgatcc gtcgcgaatc aggttttatc agcggattag tagctgtctt gcatgatgtg
     5401 acagaacaag aaaaaacaga acgggaacgt cgtgaattcg tctctaatgt ttcccatgaa
     5461 cttcgtacac cgttgacaag tatgcgtagt tatatcgaag cattgagcga aggtgcgtgg
     5521 aaagacgagg aagtagcacc aaattttttg aaggtaacgc tagatgaaac agaccgaatg
     5581 attcgaatga tcaatgacct cttaaatcta tctcgcatgg atacaggtaa tacccagctt
     5641 caattagaat atgtcaattt caacgagtta gtgaattttg ttcttgaccg gtttgatatg
     5701 atggtgggaa atcaggaaaa aaattataag atccgtcgtg aatttacgca aagagatctt
     5761 tgggtcgaag tagatacaga taaaatcatc caagtagtcg ataatatcat gaataacgcg
     5821 atcaagtatt caccagatgg gggaacgatt acttgtcgct tattagaaac gcataataac
     5881 gtggttttaa gtatcaccga tcaaggattg gggattccta aaaaagatct gaaccgagtg
     5941 ttcgagcggt tctatcgagt agataaagca cgtgcaagag cacaaggtgg gacaggactt
     6001 ggattagcta tttctagaga agtgattaag gcgcatcgag gcgctatttg ggcagagagc
     6061 aaggaaggaa aagggtcgac tttttatatc tcgctgccat atgaacctta tgaggaggaa
     6121 tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg actcattttg atggttgcgt
     6181 taagcatata cttctcttat gcaatctggc tgagcccagc aggaaaaagt tcaatcaacg
     6241 tagatgagac aaacactcaa atgatcgagt ctcaaagcaa tcgaaaaact tccgaagtct
     6301 ttcttccgct tcatgttaca tggcaccatt cgggaatgat ccaagaaacc aacagtgaaa
     6361 atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag atttggaaag ctttctgaag
     6421 tagtttcagg agacaaatca cagtttgaac aggtgaaaaa tctgaactct ggttttgagt
     6481 tggcctataa tgcgcctttt ttgctaagag aatacaagga agcatttgat ttagatttag
     6541 atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt tactagaata caattcgatc
     6601 aaggaaataa aaaaatccga tttttgaatt attcgaacca tctcgtatat gaagcaaata
     6661 tttcgttgaa ttggacagat atcaataaag aattaacagc aaaagacaca aaatggacag
     6721 aaatgacaac agaaccatcg acgatcgaca cgcaatatgc tacgaaacat tcgatcaaac
     6781 tgaaaaagta tagttatatc ctgtcacagc aaccctatac actttttaga aatgcttttt
     6841 tccagaaacc agatagcgtg aaaaataatg atgaaagcaa tgaattgatt ttttacggtg
     6901 ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt tgattttcgt ggagagctgc
     6961 cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt cccctatatt agcaaattag
     7021 gcagttcttt agggaacctc agatattttg accgcagtga caatacgatc gattatcgga
     7081 tattcgtgga aggcttcccg gtttttggga cagacagcag aggacagatt ggtgtggaag
     7141 ttggcggtga aacgaatggt tctgtgcaag tgaatatcca aaccagtttg aatacgattc
     7201 aagtgccgat accttcagac gaagaagtag aacttgcaag tacgaatgaa atcatccagc
     7261 agttaaaagc taagggagca gatagcaaca agattggttc agtgatcgtt ggctatacat
     7321 ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt acctgaatgg tatgtgaaat
     7381 ataaagataa ctggtattca gctaacgacc ttctggaaaa attacctgga ttggaggcga
     7441 attaattgga tttcaaaaaa atcgaatgga tatttttcgt cgctttttta gggttgaatg
     7501 tgtttttatt cagcagttat catgacgcgg tataccaaga aaacaatgtc attcgctcta
     7561 atcagactga atcaatccaa caacgtctgg ctagcgacga tatcacttac acggggaaga
     7621 tttcgtctga gaacaagcaa ggctattatc ttagcgcgga gcagaccaat cttagcactt
     7681 cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct ggcaagtggt gtgtttttag
     7741 acggtgatgt tttgacgaaa tctttatcca gttcagatgc tgaaaagaac gtgatcgatc
     7801 cagataaaat tagtagttcc ttggaagatt ttttatctaa caaagacaat attttattcg
     7861 gtaatgatta tgtgtacacg aaaaactttt ctcatttaga agaagaacca ctagaaatcc
     7921 aagcaagcca agagtatgaa ggcatcccat tcaatgatga tacagcaaaa atcgttcttt
     7981 ctttagaaaa aaacgataat gattatagca tcacgaaata catgcagacg catttatctg
     8041 atatcgagca gctgcgcgaa aagacggaac tgtatacgga agaggaagca atcaatacat
     8101 tgtacatcaa taacaaaata ccaagaggat caaaaatttt atggcgtcag ctagcttatt
     8161 cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc tgtttggcat gtagcgatcg
     8221 aaacaagcga taaagtggtc caaattgaga gtgtcaacgc tttcagcaat acgatcgtga
     8281 caaacaatac tgtaccaaaa gtggaagatc aataaaaaag cgagtataat gaaaaaagtt
     8341 tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga aaaaccagct tttaaaatca
     8401 gtatcctagc aagtggaagt tcgggtaatt cactttatat cgaaagtgaa aaaaaacggc
     8461 ttttggtcga tgcaggactt agcggtaaaa aaatcacttc cttgatggct caaattgatc
     8521 ggacaccgga ccaattagat ggaatacttg tgacgcatga acatcgagat catatacatg
     8581 gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt tgccaatcag cagacttggg
     8641 aagcgatgga accactgatt ggaaatgtac cagtggaaca aaaacatcta tttgagatgg
     8701 ggaaagtcag aacattcggc gatatcgata ttgagagttt cggcgtctcc catgacgcag
     8761 cggctccgca attttatcgt ttccataaag aaaatcggtc attcgtcatg ttgacggaca
     8821 ccggatattg cagtgattat atgcgaggtg tcattgaaaa tgccgatggt tatttgatgg
     8881 aaagtaatca tgatcttgag atgttacgca tgggacctta tccgtggaat ttaaaacagc
     8941 gtattttagg agatagagga catctttcca acgaagacgg tgcacttgtc atgactgatg
     9001 tgatcggtaa tcggaccaaa cgaatctatc ttggccatct tagcaaggaa aacaatatga
     9061 aagaacttgc tcatttaaca atggaaaatg ttttgaaaga aaaagatttt ggcgttggac
     9121 atgattttga aatctatgat acagatccag atgaagcaac tgagctattt tcgatttaaa
     9181 cagttcaatc aataaaaata taaaaagcag aagataaaat caatcagggt tggttttatc
     9241 ttctattttt atttttttag catattaaaa aaataaccgt attatcgact gactacactg
     9301 atgtgctgct tttcatgttt ctcatccagt atctcatcta ctaatgcaat cgcgtaatct
     9361 gccatgctga tcgtactgtc gccagcagcg tttctttgta aataatcatc acttaacaaa
     9421 taagtacctg tacgtttgcc atgtggatca aataaagaag ctggactgat ataagtccaa
     9481 tgtagatttt tagattgttt caattttaac aatccttcgt acatattgaa agctgttgga
     9541 tagaagggtg catttttagg tacttggtca atcatacgag tcgtcttttc tgtatctaag
     9601 aataacgaag aggcaccccc aacgacaatt aagcgtgtat cggttccttc aagcatctca
     9661 atcaaatggg acaaagaagt ttgatgcatt tcttcttttc ctttgggagc gttgaaagca
     9721 tcaacgacaa catcaaaaga tgcaagatca gtagttgtca actcaaataa atccttttgt
     9781 ataaacggaa catctgatgg caatttttct ggatgacgca cgattgccgt cacgtctaaa
     9841 tctctggaca atgcttcgtc taaaataaat gaacctgcat ggccagtagc tccaatgagt
     9901 gcaattttca taaaaaacct ccttttttat tcctgtccat tgtaagcagt tgctgaatat
     9961 tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt cctttcatgg ttcgtgatca
    10021 ttgggtatag ttaaattaag aaaactgatt gataaaaata gaagttgaag gagataagaa
    10081 atgaaagagt ggttagatcg tgccttttta ccaatgataa catctgttgt gaatcttaga
    10141 cccttaactg ctttgcgtaa tggaatgact tacacgatcc caataattat tgttggctcg
    10201 ctgtttttct tatttgctca ttttcctgtg gattacatcg ctcagtggat agacaaaaca
    10261 ggattttcta tgtattttac acaagtatac caggctacat ttgatgtgat agccttttgg
    10321 atcgtttttg ccattgcata cgcttatgca aaagaagaag acatcgatcg cttaccagtc
    10381 ggcataacag ccttgtctgc ttatctactg cttattcagc cactaaatac tcagatagat
    10441 actgtctgga caggtgctga agggatacta ggagcagtta caactgggct catcatcgga
    10501 tggggctatg cacgtttagt aagacttgcg aaagggtgga agcaaagaga gaagatacct
    10561 gaaaatgttt ggcagtcttt tacttcattg attccaatca ttgttatagt cacttttacg
    10621 cttatcggtt cagcggtttt tcaacagttg ttcagaatga ctgttgttca aggagtatgg
    10681 acatatgtcc agcttcccat tcaatcgttc atagacacgt tgtttggtgt gcttttatta
    10741 ggtttttttg ttccgttttt atggttattt ggtcttcatg gatctgcgat ggtcaatggg
    10801 ttggttagtc ccgtcttgca agcgaattca ttagcgaatg cagaaatctt agcctcagga
    10861 caagagttga cggtggcaaa tggcggacat atcgttactc agcaatttct cgatcagttc
    10921 atgacggtta cgggtgctgg attgacgtta ggggctgtat tttttatgac ggtttttgcg
    10981 aaatcgaaga aatacagaga attaggaaat cttgctcttt taccagcctt tttcaacatc
    11041 aatgaatcaa ttattttttc cacaccgatc gtgatgaacc cgatgatggc tgttcctttt
    11101 attttcgcac cggtcgtttc aggattgatt acctattccg ctttatattt tggattcgtt
    11161 cctttattta cagcagtcca agtcccttgg acaacaccgc cgatcctctc gggtttctta
    11221 gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag ttttttcatt
    11281 tatttcccat ttttgaaaaa aatagattct gcaaactgca aaaaggaaag acagacaaaa
    11341 aatgatggag cagcagaaaa gatgaacgac taaaaaacaa aaatactcct gtcgctttag
    11401 attgggaaaa tcaccaatct aggatgacag gagtatttat agtcatgttt atactagccc
    11461 tttttggaca gctaattgaa caagaacaac taatgtgttc attcctacgt gtgtgatcat
    11521 cgatgtccag atccgaccag ttgctttgta ctctaggctg aagaagaaac ctaggaaaaa
    11581 gtagattagc agatgaccat cattatgagc aaacgcaaac agcaaagagc tgatcactgc
    11641 tccgacccaa aaatttgaat atcgactgat gatccccagt atactgcggc ggaatacgaa
    11701 ctcttccatg atgggtccag caacagttgt cgccaaaata aaagcgggtg cttccatgat
    11761 catctggatg atattttgtg tattctcgga aggggttgct ttgccaaaca atacagattc
    11821 taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag attccaacca atccataaat
    11881 aacaatcttt ggagcagaag ctttttttac cgctgattcg atcgctaagg gttcacgttg
    11941 cttaaaataa aaaatagcta ggacaacggc gcctagtata tacatgactg cagttgctgt
    12001 gatcaattca gacgtagatt ttacaagtcc tatcgaagct aggatcaagg gtgagataaa
    12061 aattagacca tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca tgtaattcct
    12121 ccttttaagg gataacaagc atgcaaggca agcttatatc gattgatttc aattatatca
    12181 taatttcaat aagcagctgt cagaataaaa tttcttttct ttgatttaaa agcttgcaaa
    12241 aaagagggag aatgagtatt attaaaaatg taggttagca ctcgaaggtt aagagtgcta
    12301 acagattaaa aaaagagtta tcggagggat ttatcgtgtt aaaaccatta ggtgatcgcg
    12361 tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt ttagcttctg
    12421 ctgctaaaga gaaaccccaa actgggacag ttgttgcagt cggtgaaggc cgtttgttag
    12481 aaaacggtga aaaagttcct gccgctgtaa aagcaggcga ccaagttatg ttcgaaaaat
    12541 acgccggtac agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca ggaaaagata
    12601 tcatggcgat tgttgagtaa atttggaaga taaaaaaata atcaaaaata atcaatgagg
    12661 tgaatcaatc atggcaaaag aattgaaatt tgcagaagac gcacgcgcag ctatgttacg
    12721 cggggtagat aaattagcag atacagtgaa agtaacatta ggacctaaag gccgaaatgt
    12781 cgtactagaa aaatcttacg gctctccatt gatcacaaat gatggtgtga cgatcgcaaa
    12841 agaaatcgaa ttagaagatc attttgaaaa catgggtgca aaacttgtat cagaagtagc
    12901 atcaaaaaca aatgatattg caggagacgg tacaacgaca gcaactgttc tgacacaagc
    12961 aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag gcattcgtcg
    13021 cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg cataatatct caactgttgt
    13081 tgattcaaaa gaagccattg cacaagtagc agctgtttct tcgggttctg ataaagttgg
    13141 acatttgatt gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca caatcgaaga
    13201 atcaaaaggg atcgaaacag aactagatgt tgtagaaggt atgcagtttg atcgtggtta
    13261 cttatcacaa tatatggtaa cagataacga caaaatggaa gctgttctag aaaacccata
    13321 tatcttgatc acagacaaaa aaatctctaa catccaagat attctgccat tgttagaaca
    13381 aatcttgcaa caatcacgtc cattgttgat tattgctgac gatgtagatg gtgaagcatt
    13441 gccaactctt gtattgaaca aaatccgtgg aacattcaac gtagtagctg taaaagctcc
    13501 tggtttcggc gatcgtcgta aagcaatgct tgaagatatc gctattttga caggtggtac
    13561 agtaattact gacgatctag gtttagaatt gaaagatgta acaatcgaaa acttaggaaa
    13621 tgcttctaaa gttgttgtag ataaagacaa tacaacgatc gtagaaggtt ctggagaaaa
    13681 agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa caacttctga
    13741 ttttgaccgc gaaaaattac aagaacgctt agctaaatta gcaggtggtg tagctgttgt
    13801 taaagttggt gcagctactg aaacagaatt gaaagaatta aaattacgca ttgaagatgc
    13861 attgaatgct acacgtgccg cagtagaaga aggaatggtc tcaggtggtg gtacagctct
    13921 agtgaacgtt atcagcaaag tttctgctgt agaagcagaa ggagacgtgg caacaggtat
    13981 caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa acgctggtta
    14041 tgaaggatca gtgattgttg ataaattgaa gaacgtggaa ctaggcactg gtttcaatgc
    14101 tgctactgga gaatgggtaa acatggttga agcaggtatc gtagacccaa ctaaagtaac
    14161 acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga cagaagcagt
    14221 cgttgcagat aaaccagaac cagcagcgcc agcagctcct gcaatggatc catcaatgat
    14281 gggcggtatg atgtaagaaa aagcaacttg cttatctaca actgatcatt agtgaaagac
    14341 agataaaaag aggctggaac agaagcgttt aactccaaga aataagaaga aattcacgga
    14401 aattgctttt caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc
    14461 gctgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt cccacgctct
    14521 tttttgtgtg taattataat gaaaatagtt atttttaata gttataatat tttatctatt
    14581 aaaagtaaat atccatt
//
LOCUS       DADVXK010000071        14592 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.072, whole genome shotgun sequence.
ACCESSION   DADVXK010000071 DADVXK010000000
VERSION     DADVXK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.072"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            126..1865
                     /gene="yfcC"
                     /locus_tag="KB909_002005"
     CDS             126..1865
                     /gene="yfcC"
                     /locus_tag="KB909_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBB6838016.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2022..3206
                     /gene="iadA"
                     /locus_tag="KB909_002006"
     CDS             2022..3206
                     /gene="iadA"
                     /locus_tag="KB909_002006"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBB6838017.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3317..3520
                     /locus_tag="KB909_002007"
     CDS             3317..3520
                     /locus_tag="KB909_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6838018.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3621..4283)
                     /locus_tag="KB909_002008"
     CDS             complement(3621..4283)
                     /locus_tag="KB909_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838019.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4296..5798)
                     /locus_tag="KB909_002009"
     CDS             complement(4296..5798)
                     /locus_tag="KB909_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838020.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6346..8025
                     /locus_tag="KB909_002010"
     CDS             6346..8025
                     /locus_tag="KB909_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6838021.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8152..8631
                     /locus_tag="KB909_002011"
     CDS             8152..8631
                     /locus_tag="KB909_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBB6838022.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8850..9530
                     /locus_tag="KB909_002012"
     CDS             8850..9530
                     /locus_tag="KB909_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBB6838023.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9538..10869
                     /locus_tag="KB909_002013"
     CDS             9538..10869
                     /locus_tag="KB909_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6838024.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10884..11846
                     /locus_tag="KB909_002014"
     CDS             10884..11846
                     /locus_tag="KB909_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBB6838025.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11957..12295
                     /locus_tag="KB909_002015"
     CDS             11957..12295
                     /locus_tag="KB909_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBB6838026.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12374..13081
                     /locus_tag="KB909_002016"
     CDS             12374..13081
                     /locus_tag="KB909_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBB6838027.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13184..14569)
                     /locus_tag="KB909_002017"
     CDS             complement(13184..14569)
                     /locus_tag="KB909_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838028.1"
                     /translation="MPKRTIKELIRKINVSLKQFLLIDEFIYSNHKGEIQTKETDQTK
                     KLAVFSKLKLCYLKESNRFNYLMLLINYPQTAVPKKYLLEQLYISPSYLEKLTKQLNH
                     SLIKFHLRILSVKNCCTLEGNELSIRLYLYFFLSDTFGGNDWPFSSLELNALKMNSTD
                     EQIEKISKQEKNIYLLLTLFILRNKQQAYFPKTSSEITELMDLLQHTHDYSEYFTSFS
                     VSRPCEETETERAYFNYFFYCFFPNQISFRQKQEIGFLFSTSKNLICRQVGQLMTYLT
                     QQFPLNHLENKIPIYFYFLVLAVVFFELLGESSSSFSTLCFPEATSNHSSSFIQEKKL
                     REKIDTIFSKNGERNQISQYLSQLIQHLLQTETKEQLLIHLQITKQFTGNYHLQSHLQ
                     QLFRKDAVKITAYSEHADLIITDQHEKISDETETFYLDTTHNTVLFGKLIKAVHELYM
                     KKGYENKTKRM"
BASE COUNT         4641 a         2517 c         3142 g         4292 t
ORIGIN      
        1 aaaatagaaa aaagtgattt tctaataaat tattcatgtg gaaatgtcat ttttactgta
       61 taattcattt gattatccat tttttattca tcaaaattac tgaaaaaaga aaggaagaaa
      121 taaatttgaa gaaaacaaat tcttcaggaa aaccgaaacg cgacttcact aaattatcga
      181 caccccatac gtatgtcatt atttttggtg tagtcatctt tgcatggata ctgacttttg
      241 tcgttccagc aggaaagttc agcacgcaag atattgaata caaagatgca aatggcgaaa
      301 caagtactcg tactgtttta cgtcaagatt ccttccgtta tgcttacgag ctggataagt
      361 cgtatgtgtt tgatcaatta gaagaactgc aagatcatcc agcagaacgt gaaaaactgg
      421 atgttccgga aaaaggattg gaaaaagtca ttgctgacgg agaaaaaaat cttacgcagg
      481 aaaaactaga tgaaatctcc ttgacagatg atgtgcttta cgatcagtac ggcgaaaata
      541 tctatgatac ttctaaaaaa ttgcataaaa cagccaaaat atggggaaca gatgattttg
      601 gcggctttgg tttcttaaat tttgtttttg aaggactagt atctggagat aagtatggat
      661 ctgctgtagg gatcgctgca ttgatccttg ttgttggagg tgcttttggt attattatgc
      721 gtaccggagc gatcgacgca ggtatctatg cgtttatcag taaaactaag ggactggagc
      781 gtttagcttt accgctatta ttctttgctt tttcattcgg tggcgctaca ttcgggatgg
      841 cagaagaggt aattccattc tcaatggtga tggttccatt tgtcattgcg ttaggatatg
      901 actcgatcgt agcagtaacc gtgacttatg tcgcatctca agtcggaaat gcgacctctt
      961 ggatgagccc gtttagcgta gcggtggctc aagggattgc tggaatcccc gtgttgtctg
     1021 gtgcgacatt ccgattgatt atgtgggtag ttgttactgc attagccgct ggttatatga
     1081 tgatatatgc agaaaaaatc cgtaaaaaac cagaaagttc gttgacttac aaatcagatg
     1141 attatttccg ttctcatatc aaaaagacat ctgatgaaaa taaaaaattc atgcttgggc
     1201 ataaattgat cttattagag atgttagttg tccttgtctg gatcgtttgg ggcgtgactc
     1261 aaaaaggcta ttacattcca gaaatcgctt ctcaattctt tgtgatggga ttagttgctg
     1321 gaatcattgc tgttcttttc aaattagatg gaatgaaagt caatgacatc gcttcttctt
     1381 tccaatctgg tgcagctgat ttagctggta cagcaatcgt agtaggtatg gccaaaggga
     1441 ttcttcttgt cttgggagga tctgatgcat ctgttccttc agctttgaat acgattttgc
     1501 atgggatcgg gacggcgttg accggtgttc cagctgtcat tggtgcttgg gcgatgtaca
     1561 tcttccaaag tttgttcaac ttggttgtta catcaaattc aggacaagca gctttgacta
     1621 tgccaatcat ggctccactg gcagatttag taggtgtatc cagacaagta gcagttcttg
     1681 cttatcagct tggttcaggt tttatggacg cttttacacc cgtatcagcc agcttgattg
     1741 gtgtgctagg tgttgcacgg atcgaatggg caaaatgggc aagattccaa atcaagatgc
     1801 aaggattcct gtttgtttta ggaactattt tcatcatgat tgccattgca ataggtctgc
     1861 agtagtactg gagacctgta aataaaaaag taatccaaac agtagataag gactccaaga
     1921 accgtcattt tacggtaaaa tcaaaggagt aaagatccta tcgtttggat tattttttaa
     1981 gatcctatca tcagttatac ttaaagaaag aggaaaaatg tatgaaaatc attcgacaaa
     2041 ttgaagtgtt tgcaccagat tacttaggaa aaatggatgt actgattgcc ggtgggaaga
     2101 ttttggctgt agaagaacag ctagaaggcg gctacgaagg agtggaagta gaagaacttt
     2161 caggtgaggg aaaagtacta accccgggtt tcattgactg tcatttccat attttaggtg
     2221 gaggaggaga aggcggttat caaaatcgaa cgccagaagt cacattgagc caattgacta
     2281 cagctggtgt aacgacagtt gtcggttgtt tgggaacaga cggagaaggt agagatatga
     2341 ctgcgttgat cagcaaagcg aaaggtctgg aagcagaagg aatctccact tatgtatacg
     2401 aaggttcgta ccgattgccg gtaaaaacag taacagattc tatcatcaaa gactttttga
     2461 caattgataa aattatcgga atcggagaaa tcgcagtatc cgatcaccgt tcttctcagc
     2521 caagttttga agagttcgct cgtgcagtag cagatgctcg tgtaggaggc atgttatccg
     2581 gaaaagctgg gatcatcaat gtccacttag gcggaggaaa aagaaagcta gagctattga
     2641 cacgaatcgt agaagaaaca gaaattccga tcacacaatt tttgcctact catgcaaatc
     2701 gcacaccaga attatttgaa gcttgcgtgg catttgccaa acgtggtggc acgattgact
     2761 tcactgctag cgaagatcct gatttttggg agaagacaga tggtgaagtt cgcttcagca
     2821 aagcactgaa acgattgatc gaggaagatg tttctttaga taatttcacg atgacctcag
     2881 atggacaagg aagcttgcct tattttgatg aaaacaatca tttcctaggg ttaggagtag
     2941 gaagtgccaa ggcattgcta gtagggatca aagaagctgt gcaaaaagaa agtatccctt
     3001 tggaaatcgc cttacgagct ataaccagta atccagcacg tatattgaaa ttggataaaa
     3061 aaggaaaaat cgaaattggt gctgatgcag atctgtgtat cttggataaa gaaacgcttg
     3121 atattgatac agttatcgct aaaggagaaa taatggtcca agaaaaagaa gtcaaagtat
     3181 gggggacttt cgaaaaaagt ttttaatcaa cagctctaac tatctttttt agaaaacgag
     3241 cgttctgttt gtctgtatct gttgttgatg ttaccctgaa ggtagatcaa taaacaaact
     3301 aagaggagga agcacaatgg cagatttaaa aggacgttct aaagatatga aagataaagt
     3361 agtcggtgaa ggaaaagaag catacggcaa agcaacagac gacaagagca aagaaacaga
     3421 agggaaagca caatcactag gtgctgacat caaagaaaaa gctcgaaatt taggcgacga
     3481 agtcaaagac aagttttctc gaaaagacga aaaaaaataa aaaccactta ttactaattg
     3541 aatcaagcaa ataaaaaatc cgaaccatat ctgcgagaca gatatggttc ggatttttta
     3601 tttgatcatt atcctgtttt ttaaacttcg attttttgaa attttttatt ttttagttca
     3661 aagacttcat cacagctttt tgctacttca atctcatgag tcacgatgat aatacagcga
     3721 ttttgttcat gggcgatttc ttggaaaagt ttgacgatat cttgtgaagt tgtttcatct
     3781 agatttccag taggctcatc cgctacgatt agttgatgtt cacagcagat agcacgaacg
     3841 atagcgactc gctgctgctg acctcccgaa agtttggtca cctgtttttt tgctaatatt
     3901 tcatcaattc ctacacgagc cagtcgatct aaagcaactt gtcgataatt ctcttgcttg
     3961 gtcttagtga tttccattgc tgctatgacg ttgtctagag ccgataaata aggaagcaag
     4021 ttgtaagctt ggaaaataat cgagacatca tttttacgat aacttcttaa cccgattttg
     4081 ttcagtgaac gatcttgata gtataccttt ccttcttttg gtgcatctag tccagaaata
     4141 agcgaaagaa aagtcgtttt tccagaacca cttgctccta aaatagcgta catttttcca
     4201 gcttcgaaat tcagttctac atctttataa agcgcatctt gcggatcttg ataccaaaat
     4261 cccaattgtt ctgtccgtaa catcaaattc ctcctttagt ttaataggat ttttcttggg
     4321 tttaatctta atatccctat agaagctaaa aagacagaaa acagactgat tccaaatgct
     4381 actccggcta atagtcccaa ttgtgcaggt ttgacattga tttccaattc gctgacttga
     4441 tcagaaacag caaatggatt attcgtggtt ccttgttgac catcgcgttg accgccttgt
     4501 tcttgtctgt tacctggcat ttgtccaccg ccaggagctt gctggttttg tgtcgtggtt
     4561 tctgtctgtt ggtcaagtag ctgctgtccc acggcattcg cgacgacgtt tccgctaagc
     4621 gaagcaactc ctaatgcaag aatcatacaa atagccactt cggtaaacaa ttggagaatg
     4681 attttacttc tggattctcc taaagatagc aagacgccta actcatgccg acgctcccga
     4741 atggtaatca taatgatcag agtaagtatg ataataccgg ctacagccac tagtaaaaca
     4801 acatttttag aaaaacttgc cacgttgttt aaaggttcca acattgactg atacatggaa
     4861 tcatttgatt gtaagctaaa tgtatctgtg tcgatcagct tctcagcttc tttgagaaac
     4921 tcatccattt tatctggatc agatagagtg taaatagcag aatctatcgt gttatcgtca
     4981 gatgtcccat ttagttcatt tgcaaaagtg taagaagtgt aaagtgtatt cgacggattc
     5041 atgaagttga atttcatacc catactgccg cttgtttcgc tggattcata aattcctttg
     5101 atcgtcattt cataagtggt atcttcatct tcagtactcg tgattgtgaa agtatctccg
     5161 actgccaggt catttgtttc tgctagagta gaatcaatga ctacattgtt tgtgcctttg
     5221 tcgctgtcat ctattccttc accatccgtg atttttgctg ttccatcaga aaaattacta
     5281 ttttgtgcag ttgctgacac accactgatt tgaaagtctg cttgagtcat ttgcggattc
     5341 ccgcccattc ctccagcagg ttcaccgcct gcatcagtag tttctgaact gtcttcactt
     5401 gaatcagaac tagtgatggc agttattcca tcttttgcca tagctgaggc ggaactttca
     5461 aaggaataac tctttacatt atctaattca gctatttttt ccgcgtccgt taaggaaact
     5521 ggtgtaagag aaaaactgcc tggatctgga cgttcttcag tggtagaacc gcttgaagaa
     5581 gtttgttcct gttttttaaa tgaagcttct cgattggcac ttaaagtcac tgttgctcca
     5641 acttcttttt gtgcttgatt cgctgcttct tctgcagcgc ttcgaatcgt gaggccagct
     5701 agcacaaaaa taagaatggc tgtgaacacg gcaaacaata acaatgaacg tccccatttt
     5761 acttttgtac ttttccatgc acgtttcata aaattcatat tttgcatccc tcctagtaga
     5821 tgcatttgat aatagacaac ctatcttaaa gctagcttaa atcttatgct gtttgcacac
     5881 catcaacatg aggttctgta tatataaaaa gtcactatag ttattgcaaa aaatgtggta
     5941 aaatgaaaaa agtatgtttc aaaccgacga agaagaaatg aaagaggaat agcaaaagaa
     6001 atcctagatg ctacagaggg atttttacgt gcatagttgt tctaacaatt gctgatacta
     6061 gcgatttagt ttatttgttg tataataatg gggaacagct gaatacttat ataagtattc
     6121 tggctatagc gtttcgcaaa agatccattt tgttaatgaa gtatatccaa aataaaatgc
     6181 ccatccaact gtcagaacgc ggatgtgctg gtaattttcc tgctgattct ccataagttg
     6241 agaaatagtg attttgcata tgcttcattg gaatggctca tatatttaga taaagaagaa
     6301 aatcgacatc tttaaacttg gatgtcataa gaagaggtga agtttgtgag taccattaaa
     6361 attatcccat taggcggcgt tcgtgaaaat ggaaaaaaca tgtatgtcgc agaagtgggc
     6421 gaggatattt ttattttaga ttgtgggcta aaatatcctg aaaatgagtt gttggggatc
     6481 gacgtcgtaa tccctgattt tacgtattta gaagaaaaca ttgatcgtgt agctggtgtc
     6541 tttttaacac atggacatgc agatgcgatc ggggcacttc cttacttgtt gtcaaaaatt
     6601 tctgtaccag tattcgggac agagttgacg atcgagttag caaaattgaa tgtcagtcgt
     6661 aatgaagcag ccaaaggatt taaggatttc catgtggtag atgagcatac agaaatagac
     6721 tttggtgaaa cagtagtgag ctttttccgt accactcata cgataccaga ttcagtgggg
     6781 atcaatctga aaacaaaaga aggtagtatc gtttatacgg gagattttaa atttgaccaa
     6841 acggctatcc caatgtatca aacagattat gcacgattgg cggaaatcgg caaagaagga
     6901 gtcttagcct tactaagtga atcggcaaat gcagaaaatc ctcagcctgt agcttctgaa
     6961 gcccaaatag cagatgaagt atttgatacg atcaaatatt gggaagggcg tatcatcgtc
     7021 gcttgtgtag caagtaattt gcaacgagtg caacaagtat tggatgcagc agaaaaagca
     7081 caacgaaaag ttgtcttgac tggtcaagat ttcgaacgaa ttattcgcac agcgatgcgt
     7141 ttagaaaaac ttcaattacc aagtgaagat ctgcttgtta cgttgaaaga catgaaaaac
     7201 tatgatccag aagaactgat cattttagaa actggccgaa tgggtgaacc catcaagtct
     7261 ctgcaaaaaa tggcaaacgg tacacaccgt aatgtcaaga ttgaagaagg agatttggtt
     7321 tatatcacta ctacgccaag catcgcgatg gaaaccatcg tggcgaaaac ggaagatatc
     7381 atttatcgag ctggtggaac agtgaagttg atctctgaga atatgcgcgt ttctggccat
     7441 gccaatccta atgacttgca attaatgatc aatttgatga aaccaacata ttttgtgcca
     7501 gttcaaggag agtatcgtga attagctgct catgcagatt tggctcatgc agtagggatg
     7561 ccatacaaaa atatctatat tactggacgc ggagacgtgc tggaatataa gaacaagcgt
     7621 atgagtgttg caggaactac aagtgcagaa aatgtaatga ttgatggatt aggcataggt
     7681 gatatcggaa acattgtttt acgtgatcga aaaatcttgt cagaagacgg gattttcgta
     7741 gcggttgtca ctatcagtcg gcgagaaaag aaaatcattt caaaacctca aattacttca
     7801 cggggattcg tttacgtaaa agctagccgt gatctgatga aagaaagcag caatatgatt
     7861 gaaacaatcg ttgagaaaca tttagaaagc aatgattttg agtggagcaa attaaagcaa
     7921 gacatccgag atcaattagg ccgttactta tttgaacaaa caaaacgccg cccagtgatc
     7981 ttgccagtca ttatggaagc tactcaacgt cgaaataaaa aataaacaaa aagagtaaga
     8041 tgaacctctc tatagagtgc tcgtcttgct ctttttttgc gaaaaacaaa taatttttga
     8101 atacagcatc cctcgcttta taataaacga tagaataaag ggagtgaatc aatgatgagt
     8161 caaacaaaag tcgaacgtta tttagaagaa caaaagatca gctatcaacc acttgatttt
     8221 agtcatgtgg tagaagaatc tttcacagaa gaactacaaa aaagagggat tgatccagct
     8281 ttgatatgta aaactctcgt agtgaaagga aacaaaactg gggtgatcat cgcattgatt
     8341 cctttgaacg atcacttaga ttacaaaaaa acgagacaag tgacgaaaga tcgtaaagtt
     8401 ggttttcctg gaatggattt tgtattaatg catacaggat atccccacgg agcaaacacc
     8461 cctattggaa taaaactcgc acatcctgat tattgttttt tagcagacag ttctttaaaa
     8521 gaaaaagaag aagtaattgt gtcaagcggt gaaatcggga gaagccttcg gataaaagta
     8581 gccgatttag aaaagatcgt ccatcctatt tacgctgatt taattagtta agggacgaga
     8641 agagaagcta agcagagcag agacctcaaa cttgagatta tatctgcttg gtacttggtg
     8701 catcctgtat tatctgttac aattgctttg tacatactgt actatcaatc caatgaaaat
     8761 atatttagca gctatatttt ttcattgatg tgcaagtgat gaaatcgttt ttaataaaaa
     8821 agatacagag aaaacgcgag gtgtaaaata tgaaaattac gtatcatgga cattcctgtt
     8881 taacaattga aatggaaaat ggccaacgcg tgatgattga cccgtttatt acaggaaatc
     8941 cattgacaga cttaactgca gaagaagtaa agacagattg gttgctgatt actcatggtc
     9001 atagtgacca cataggagat atgattccta ttgcaaaaga aaatcaagcc acaattatca
     9061 gtattgttga gattgctgat tatgcgaaca gcagaggagt agattcattc ggtatgaata
     9121 tcggtggaaa acatgcgttt ccattcggcg tggtaaaatt cgtacatgca cagcatagtt
     9181 caagctatga agtagacggt atcgttcagt atatgggcga gcctagcgga attattattc
     9241 aagcagaagg aaaaacgatt tatcatgcag gggatactgc ttatttcagt gatctaggat
     9301 tgcttgcaga agaattcgat attgatgtcg ctttcttgcc gattggcgat aactatacga
     9361 tggggccaga agatgcagca aaggctgcgc aaacaattcg tgccaagaaa gtagttccaa
     9421 tccattacaa tactttccct gtcattgaac aagatcccga atcttttgta gagttactgg
     9481 aagatagtga aggaaaaata atgagcgtct cggaaacgct ggaagtgtag gcagaaaatg
     9541 gcgacaaaac atgatttgat tttagaatat attgaaagtt tacctgttgg caatcgaatt
     9601 tctgtaagaa gcatcgcaaa agaattgaat gtcagtgaag gaacagcgta ccgtgcaatc
     9661 aaagatgcag aaaatgtcgg actagtttca acaattcaac gagtagggac catccgtatc
     9721 gaacgcaaat taaaaaaaca tattgaacgt ttgacatttg gcgaggtcgt caggatcatt
     9781 gaaggggacg ttttaggcgg ggcggcagga ttagacaagg tcttgaataa attcgtcatc
     9841 ggcgcgatga ctaaacatgc catggaacgc tatattacgc caggatcact aatgatcgtc
     9901 ggcaaccggg cggaagtcca aaaattagca ttggaagatg gcgccgcagt attgatcaca
     9961 ggaggattca atacgactgc tgagattgca aagctagctg atgatcttga aatgccgatc
    10021 ttacgcacct cttatgatac atttacagtc gcaaccatga tcaaccgagc gttaagcgac
    10081 caattgatca aaaaagatat catgcttgtc agtgatatct atatgccagc tgaaaagact
    10141 cattatttgc agcagacaga tacgatttct gattatcagc gtttgtcaga agaaacgcag
    10201 cattcgcgtt ttccagtcgt caaccgccat catcgtttga tggggattgt tacggcaaaa
    10261 gatgttttag ggaaatcgcc aaaccagatc atcgatcggg tgatgacgaa agaaccaatc
    10321 agtgtaaaga aaacaatgag tattgcctct gttagccatc aaatgatctg ggatgggcta
    10381 gaagtcatgc cggtcgtttc cgatgacttg acattggaag gcttgattac ccggcaagat
    10441 gtaatgaaag cgatgcagct tgtccagcga caaccgcaga ttgcagatac gatttcggat
    10501 cagatatctg gaaatatcca tacgattgat actgaccgtg aaggaaatcg tttggaaaac
    10561 cctaagttca aattcgtagt agcaccacaa atggtcaatg gcgttggaac catttctttt
    10621 ggcgtactta gcgaaatcat ttctgatgtc gcacaaaaaa caatggtgat gaaccaaaaa
    10681 cgaaatatct tgattgaaca agtgaaccta cattatttgc ggctgatcca attggaaagc
    10741 gaattagaca ttcgtccacg tgtattggaa atcggcagac gttccgctaa actggatatc
    10801 gaagtgttta ttgaaaacac catcgtttcc aaagcaatcg ttgtttgtca agtaatggaa
    10861 cgttcttaga aagcaggagt gaaatgacag tacagcaaga aatagtagat acaataaaaa
    10921 aatacgataa aatcattatc cacaggcatt tgcgccctga tcctgatgca ttaggatcac
    10981 aagtaggatt agccgaacta ttacgggaaa gtttcccaga aaaagaaata cgtcaagtag
    11041 gtgaaacgat tgaagggctt cgctttttag cagaaatgca agaagttgaa gatgtcttct
    11101 accaaggagc gctagtcatc gtgactgata cagctaattc acccagaatc agtgatcaaa
    11161 gatatcagtt ggcagaaaaa ctgatcaaaa tcgaccatca tcccaatgat gacccttatg
    11221 gagatcttgt gtgggtaaat acaaaagcaa gtagctgtag tgagatgatt gcagaatttg
    11281 ctttgatgtt tcctgaatct ttaaagatga acgttaaggc tgcacggtta ctttatgcag
    11341 gaatcgtcgg agatacaggg cgctttttgt atccctccac gacgtcccgt acattagaga
    11401 ttgcttcgat attgagaaat tatccatttg atgcaagtgc tttgaacaga gagattgaac
    11461 aaatgccgat gaaagtcgct aaactttccg gttatcttta tcaaaatatc caggtggatg
    11521 aaaatggtgc aggaagaata atccttccgc aagaaattct tgataaatat ggaatcgatg
    11581 attcagagac agcttcgatc gtttcacttc ctggagtgat tgacgaagtg ctggcttggg
    11641 ggatttttgt tcagcagcct tcagggtatt accgcgtacg tttacgttct aaggggccga
    11701 tcatcaatga attggctaaa cgccatcatg gaggaggcca tccattagca agtggtgcga
    11761 atgcaaaaga tttagcagaa gtagaggaaa tctataaaga gatccaagat atatgccaat
    11821 cgtataagag cagaaaaaca gaatgatact tcgttcgaaa acgtgccttt tgtagtaaaa
    11881 atcacaaatg tatcttttca agatcttctt tttccgttac aatagtgctc actaaagatt
    11941 ttaaaggaga aagaagatga cattaccaaa ttgcccagaa tgtggctcag agtacacata
    12001 tgaagatcga ggcttgttga tttgcccaga atgcgggaac gaatggaaca aagaagaaca
    12061 agaaactgtc atagaagacg gattagtggt attagatgca aatggaaacc gtctgttaga
    12121 gggcgatagc gtgacagtga ttaaagactt gaaagtaaaa ggtgcgtcag gtgccattaa
    12181 acaaggaaca aaagtcaaga acatccgttt agtagaaggc gatcataata tcgattgcaa
    12241 ggtagaagga tttggaccga tgaaactgaa atcggaattt gtgaaaaaga attaaagaat
    12301 attcaaggtc ttttcacatt cttttcctac tactaatgat aaaataaagt aaacgaaaag
    12361 gagtgaaacg aaaatgtatg gttatggaat gtatggtttt ttagatccga catttctttt
    12421 ggtcattctt ggattagtta tttccggaat tgcgtcagcg tacgtcaata gtactttccg
    12481 aaaatacgat caagtgagaa gcaaaaacaa tgtgactggt acacaagcag cacaatatat
    12541 attacaaagt caacagataa ataatgtcgg tgttcaacaa attgccggag atctcacaga
    12601 taactacaat tcaggtaata agatgttgag tttgtctcaa gcaactgcac agtctacttc
    12661 agttgctgcg ataggtgtag cagctcatga atgcggacat gcggtacaag atgcttcggg
    12721 ttatgtccca ttgaagattc gtgcagcact tgttccagca gctaactttg gttcgatgat
    12781 ttcgttcccc ttgattatgg taggtgtatt gcttagctgg aactctacgt taatcaatat
    12841 cgggattttc gctttttctt tagcattact tttccaattg gtgacattac cagtcgaatt
    12901 taacgcgtct cggcgagcaa tccaaatttt gagtgaaggc ggactactga cggaagaaga
    12961 agtaccgatg gcaagacacg tattatttgc agcagcactg acttatgttg cagcagcgct
    13021 ttcgacattc ctgcagctgt tgcgcttgat cttattgttc ggcggcaacc gaagagatta
    13081 aaataaagaa gttgtgaaat cagcgctttg atctgagcta ataccgagag ttagctgatt
    13141 gaataccatt tatttggaat aagaggatgt gacaagaatt ttgtcacatc ctctttgttt
    13201 tgttctcata accttttttc atatacagtt catgaaccgc ttttattaac ttgccaaata
    13261 acactgtatt gtgcgttgta tccagataga aagtctccgt ttcatctgaa attttctcat
    13321 gctgatctgt aatgatcaaa tcagcatgtt ctgaatatgc ggtaatttta acagcatctt
    13381 tgcgaaataa ctgctgcaaa tggctttgaa gatgataatt tcctgtaaac tgtttggtta
    13441 tctgcaaatg gatgagtaac tgctctttcg tttctgtttg tagtaagtgt tggatcaatt
    13501 gactaaggta ttgactgatt tggtttcttt ccccattttt tgaaaaaatt gtatcgattt
    13561 tttctcttaa tttcttttcc tgtataaaag aactagaatg attggacgtg gcttctggaa
    13621 agcaaagtgt agaaaaacta ctgctggatt cacccaacag ttcgaaaaaa acaactgcca
    13681 acacaagaaa ataaaaataa attggtattt tattttctaa atggttgaga ggaaactgtt
    13741 gagttaagta agtcatcaat tgaccgactt gtcgacaaat aaggtttttg cttgtggaaa
    13801 ataaaaaacc aatctcctgt ttttgtcgaa aagagatttg atttggaaaa aaacaataga
    13861 aaaaataatt aaagtaggct ctctctgttt ctgtctcttc acaagggcga ctcactgaaa
    13921 aagaagtaaa gtattctgaa taatcatgtg tatgctgcaa taagtccatc aattcagtga
    13981 tttcagaaga agtttttgga aaatatgcct gttgtttgtt tcgtaatatg aataaagtta
    14041 acagcaagta gatatttttt tcttgttttg aaattttttc tatttgctca tctgtactgt
    14101 tcatttttag tgcatttaat tcaagtgagg aaaatggcca atcgttacct ccaaatgtat
    14161 ctgaaagaaa aaagtaaaga tagagacgga tagataactc atttccttca agagtacagc
    14221 aattttttac agataggatc cgtaaatgga attttattaa ggaatgattg agctgttttg
    14281 tcagtttttc gagataggag ggcgatatat aaagttgttc aagtaaatat ttttttggta
    14341 cagcagtttg tggataattg attagtaaca tcaaatagtt aaaacgattg gattctttta
    14401 ggtagcataa ttttaactta gaaaaaacag ctaacttttt agtttgatcg gtttctttgg
    14461 tttggatctc tcctttatga ttagaataaa taaattcatc aatcaataaa aattgcttga
    14521 gtgatacatt tatttttcgg atcagttctt tgattgtccg ttttggaata tgtaagtcat
    14581 tggataattc tt
//
LOCUS       DADVXK010000072        14264 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.073, whole genome shotgun sequence.
ACCESSION   DADVXK010000072 DADVXK010000000
VERSION     DADVXK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.073"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(41..3715)
                     /gene="rpoC"
                     /locus_tag="KB909_002018"
     CDS             complement(41..3715)
                     /gene="rpoC"
                     /locus_tag="KB909_002018"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBB6838029.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="KB909_002019"
     CDS             complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="KB909_002019"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6838030.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8118..9086
                     /locus_tag="KB909_002020"
     CDS             8118..9086
                     /locus_tag="KB909_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6838031.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9104..10009
                     /locus_tag="KB909_002021"
     CDS             9104..10009
                     /locus_tag="KB909_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838032.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10006..10812
                     /locus_tag="KB909_002022"
     CDS             10006..10812
                     /locus_tag="KB909_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838033.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10948..11937
                     /locus_tag="KB909_002023"
     CDS             10948..11937
                     /locus_tag="KB909_002023"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBB6838034.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12254..12778)
                     /locus_tag="KB909_002024"
     CDS             complement(12254..12778)
                     /locus_tag="KB909_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBB6838035.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13065..>14264
                     /gene="scm"
                     /locus_tag="KB909_002025"
     CDS             13065..>14264
                     /gene="scm"
                     /locus_tag="KB909_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6838036.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTD"
BASE COUNT         4044 a         3083 c         2815 g         4322 t
ORIGIN      
        1 gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca
       61 ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg
      121 ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga
      181 tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga
      241 tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat
      301 ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc
      361 ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac
      421 ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa
      481 ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta
      541 cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg
      601 gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt
      661 tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta
      721 cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg
      781 tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac
      841 cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag
      901 taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt
      961 cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac
     1021 atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga
     1081 tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta
     1141 cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc
     1201 cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga
     1261 ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca
     1321 aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg
     1381 atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg
     1441 ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag
     1501 aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga
     1561 tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga
     1621 tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga
     1681 tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg
     1741 tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt
     1801 tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata
     1861 ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt
     1921 ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag
     1981 gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc
     2041 attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat
     2101 gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt
     2161 cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc atatcttggg
     2221 aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca
     2281 acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc
     2341 catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt
     2401 gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca
     2461 gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac
     2521 gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac
     2581 gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca
     2641 tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta
     2701 gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg
     2761 ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta
     2821 ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta
     2881 acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac
     2941 ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag
     3001 ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa
     3061 tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt
     3121 tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg
     3181 cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt
     3241 ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag
     3301 caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg
     3361 aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca
     3421 tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc
     3481 ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa
     3541 aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct
     3601 caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta
     3661 tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat
     3721 ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta
     3781 aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt
     3841 cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat
     3901 caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt
     3961 cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga
     4021 atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt
     4081 tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg
     4141 caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag
     4201 ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca
     4261 atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc
     4321 catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac
     4381 cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg
     4441 ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga
     4501 tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag
     4561 gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac
     4621 gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta
     4681 acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt
     4741 gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt
     4801 tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg
     4861 gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac
     4921 ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt
     4981 cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag
     5041 tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc
     5101 cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca
     5161 tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg
     5221 gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat
     5281 ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac
     5341 cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag
     5401 taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac
     5461 ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
     5521 caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt
     5581 tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg
     5641 ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt
     5701 ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga
     5761 atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag
     5821 gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac
     5881 cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca
     5941 attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt
     6001 ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag
     6061 tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga
     6121 attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat
     6181 catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt
     6241 cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt
     6301 cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga
     6361 ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag
     6421 ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg
     6481 tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta
     6541 attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga
     6601 aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac
     6661 gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt
     6721 ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat
     6781 cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga
     6841 tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag
     6901 ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga
     6961 cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg
     7021 ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc
     7081 cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat
     7141 gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca
     7201 aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc
     7261 cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca
     7321 acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt
     7381 gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt
     7441 tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg
     7501 caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt
     7561 gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat
     7621 agtttttgca acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt
     7681 tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga
     7741 caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga
     7801 ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac
     7861 tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt
     7921 tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct
     7981 aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta
     8041 ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa
     8101 ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac
     8161 tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa
     8221 caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca
     8281 aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa
     8341 atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc
     8401 ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca
     8461 ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca
     8521 atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa
     8581 tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg
     8641 gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg
     8701 tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc
     8761 tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa
     8821 gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc
     8881 aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggtaaacaaa
     8941 cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa
     9001 cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc
     9061 cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc
     9121 tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata
     9181 cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg
     9241 tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct
     9301 aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa
     9361 aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg
     9421 tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga
     9481 gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat
     9541 cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac
     9601 tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat
     9661 cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa
     9721 cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat
     9781 catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt
     9841 aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag
     9901 tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca
     9961 gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta
    10021 acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg
    10081 aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg
    10141 gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa
    10201 attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc
    10261 agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat
    10321 cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa
    10381 gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta
    10441 tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc
    10501 acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct
    10561 acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct
    10621 tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg
    10681 catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc
    10741 caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt
    10801 ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt
    10861 ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt
    10921 gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa
    10981 gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca
    11041 cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca
    11101 ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat
    11161 gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg
    11221 ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg agattctgtt
    11281 tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt
    11341 ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt
    11401 gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct
    11461 gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa
    11521 gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc
    11581 atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa
    11641 gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc
    11701 agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc
    11761 tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact
    11821 tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa
    11881 cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta
    11941 tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca
    12001 aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta
    12061 aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag
    12121 tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata
    12181 gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt
    12241 tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag
    12301 agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg
    12361 tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa
    12421 tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga
    12481 tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg
    12541 gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa
    12601 tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg
    12661 gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac
    12721 gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt
    12781 attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata cctacttata
    12841 tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga
    12901 ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt
    12961 cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa
    13021 aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa
    13081 gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag
    13141 cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg
    13201 gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg
    13261 cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag
    13321 agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg
    13381 ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta
    13441 acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact
    13501 taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg
    13561 aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat
    13621 atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag
    13681 ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc
    13741 aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat
    13801 tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt
    13861 cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc
    13921 cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg
    13981 gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg
    14041 aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat
    14101 ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat actacctcta
    14161 ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact acctctacca
    14221 caagtgatag cacggacaca tcagcttcaa gtgacagtac agat
//
LOCUS       DADVXK010000073        13493 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.074, whole genome shotgun sequence.
ACCESSION   DADVXK010000073 DADVXK010000000
VERSION     DADVXK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.074"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(110..802)
                     /locus_tag="KB909_002026"
     CDS             complement(110..802)
                     /locus_tag="KB909_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6838037.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1239..1808)
                     /locus_tag="KB909_002027"
     CDS             complement(1239..1808)
                     /locus_tag="KB909_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6838038.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1882..2205)
                     /locus_tag="KB909_002028"
     CDS             complement(1882..2205)
                     /locus_tag="KB909_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838039.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2359..3171)
                     /locus_tag="KB909_002029"
     CDS             complement(2359..3171)
                     /locus_tag="KB909_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838040.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3524..4372
                     /locus_tag="KB909_002030"
     CDS             3524..4372
                     /locus_tag="KB909_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBB6838041.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4517..5458
                     /locus_tag="KB909_002031"
     CDS             4517..5458
                     /locus_tag="KB909_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBB6838042.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5448..7619
                     /locus_tag="KB909_002032"
                     /pseudo
     CDS             5448..7619
                     /locus_tag="KB909_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7731..9902)
                     /gene="copB"
                     /locus_tag="KB909_002033"
     CDS             complement(7731..9902)
                     /gene="copB"
                     /locus_tag="KB909_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBB6838043.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(9922..12108)
                     /locus_tag="KB909_002034"
     CDS             complement(9922..12108)
                     /locus_tag="KB909_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBB6838044.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12108..12317)
                     /gene="copZ"
                     /locus_tag="KB909_002035"
     CDS             complement(12108..12317)
                     /gene="copZ"
                     /locus_tag="KB909_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBB6838045.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12330..12770)
                     /locus_tag="KB909_002036"
     CDS             complement(12330..12770)
                     /locus_tag="KB909_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBB6838046.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12844..13383)
                     /locus_tag="KB909_002037"
     CDS             complement(12844..13383)
                     /locus_tag="KB909_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6838047.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3791 a         2826 c         2400 g         4476 t
ORIGIN      
        1 ctgaacccca aaagttgaac tatttaatgg actgtttccg atattctact ggagatagtc
       61 cattaaatag ttcaactttt ggggttcagt tcaaagaggg ggggattttt tatcgttgtg
      121 gaatatttaa ataccaacgc ttgtcatgaa aatcttgtgc tccaccctta gtatttcctt
      181 ctggatcgtt tgtcgcacgc atcatgacgt atactttctt attagggaaa tcacgcatat
      241 tgaaagatac atgatagcca acatttccta aagtattata agcttgattt acgtctggtc
      301 tataaatccc atcagctctt actctagcta gttcttttcc agtattgtag tccataatga
      361 aaatatactc gtatttataa ttagcaatgt gccatccagc tacatgcaag tttgcgtttt
      421 cgatttctcc gaactgatca atgtgggcgt aatttgttcc atctgtcagc gtagaatttg
      481 cagcacctgc tcgagttgga tcaattactg gtttatcctc cgaagtagtt ggattatcat
      541 ccgtaaaacc atgagccaaa tcataggcta gtttttcttt acttacaccc atttcagaaa
      601 gataaccgta aggatctgta tgatcgcccc aaatattttg tgttacccat aaatgcgatt
      661 tgattcctgg ttggttataa ggagtgtcta atgttaatgg aataccatat ttcattgctg
      721 aatctcttgc caattcaacg tatactttat agttcttttc aaaagtttct ttatcatgtg
      781 tatgttgtaa ctcgatttgc acaggacttt tggctcacga ggttgtccta ctctacatct
      841 tgctgataga tatgctgaaa ggaaaacacc aacattatgt tttgcttttt cagctagaac
      901 gagacaagca ggaatacctt tagaagatat caaaggtttt ttaggtcata aagatgtttc
      961 cactacacaa gtctatgccc atatttctcc cgaagtgaaa aaaagatcaa tgaatcaact
     1021 agaaaactat atagaagagc aaataaaaaa gcactcaaat tgagtgcttt tttaagctca
     1081 ctatcactaa aactatcact aattttattt ataagcgaac atgtttctat cactgatttt
     1141 ttaaatctag cgaaaaaccc ttatcttaaa ggcgttcgtt caattctttg gcaaggtctt
     1201 caaagcctgg cttgcctaga agtgcgaaca tggttttctt atagctcatg tagaaaaatt
     1261 ttcttgatga tgattttatc catcaattga gattgactgt tttgctctcc tatgatttca
     1321 gctatgattg tccgattttg cggttttctt cttaactggt agttgatttt cccagtttcc
     1381 atcaactcgc taagcatatc cacgactccg ccaaatccgg tctttttcgt aataaaacct
     1441 agtgctacca ttcgttcatc tagatttttt gctgtaatcg tcacaccagt aatgagcgag
     1501 tgctgtaatg tttgggccag ctcttccatc ccttcagcat tggatacgac ggaagctgtt
     1561 ttgttaatag gttcttcgtt tatttctttt ggttctttcc tctccacttt cactgtttga
     1621 cgaaggacat ctagttcttg caagagcgtt tcgtattgtt cttgggtcag catcacgcca
     1681 gctacttttt cacgattaaa tatatatacg ccagttcccg cgtctcgcgc ttgagcaaat
     1741 acatccatcg gcgatcgttt cacttctgtg atcgaagatg tgggaacttc taatttcttt
     1801 aattccaatg gatttcctcc tttactaatc gctttttatt atagcacaga ctgacttgtt
     1861 ttgatctttt ttccaaaggt tttatcggtt tttgcctaac cagtaattga tatcggtaag
     1921 aagtctttcg ataccaaatg aaggatggta cagatacgtt ttttgatctt cgttatggtc
     1981 tagtggaaaa aaatgatcga tgatcactag atctgcatac cgaggcggct tatttcgagt
     2041 acatacatgt atagagatcc gttttcgatg tcttagcgtt ttgttcagta ccccagcaag
     2101 tcttcttgct tcttggtgtt catagcgaaa aaaaaagacg attttcactt caggagggtg
     2161 gacatctaaa taccctcgtt cctggagtgt tttcagtaaa agcatccccc actctactgc
     2221 ggggtgtgca agtgcttgtt ggatcgctag ccgaaattga tatagtttat ctttggaatt
     2281 gggaaatttt tctaatgttt cctgataata acgaacttct tctatcagcc ggtcatggat
     2341 accaattacg taacgaagtc attcttggta aagtactttt gtcagctttg atttgctttc
     2401 gctctcaaat tcgctattca gccaaaacag cgaatcaagc ttttcagtca caatcgtcaa
     2461 tttccgatag tcttgtgtct cttctatccg tttccaccgc ttttcagtaa tctggttaca
     2521 gctcaagcgc aaaattgcta gataattttt ttcttttatt ggcaaaatct gctcctctct
     2581 aaatagcaat tcaggaaaca attcaaagaa tagtgttcga ctgtctccta aaatctcgat
     2641 ttctgccgga tcctttcttt gcttcaataa ttggatgaac atctcagaaa aggactgctc
     2701 tccatcatct gcaaaaaaat gcggaaaatc tttcaaaaag caaaacagca gatatcttac
     2761 ttttctttct gaaccaaaga tctgtgcttt tttataagaa aaagaaaggt ggtactcgcc
     2821 aaaccacttt ctcaatcgct cttgcgtaga acgatcgtac ttctgctcgt aaggttcatt
     2881 caatagcaga tttttcagta aacaaaacgg gggtgattgg atcagaaaaa caaacaagag
     2941 ataaggttcg ctatatcctt gatcataaac taactgaacg gttttcttat gaagaatcag
     3001 ctgaatggga cagtcgcttt ccgccaaacg tttcagatgc cgatccactg ttttaacatc
     3061 gattttcagt tcttcagcta aatcagcttt tcgccagatc aaatctttca ttagattgat
     3121 tagtgaaaat aaattctgtg cattttttga taatagtttt tgccatctca tcgatcattt
     3181 ctcacctgat ttctaaacat attgtttgat caaaatgggt tcactcctaa aaagataaaa
     3241 aactcccttt ctatttattt aaatacgcaa atcttcctca ttatttttta ttttactcaa
     3301 tttaatcgta ttctcatttc aaaacgaatg tactttaaaa aacataataa gatcactttg
     3361 cttgtaggat gtattccctt ccattacaat gaaataaata gcgattttat gagaaggtga
     3421 tgtgaaaatg gaagaaaaaa tagaagaatc caaacaaaaa atcgatcagt tgatataaga
     3481 attagaaaaa gcggtcatcg gcaaacgttc aactatccaa ttgatgatcg tggccctatt
     3541 agcaggtggt catgtcttat tcgaagatat tcccggtgta ggtaaaacgt tactggtcaa
     3601 agcactagca aaagctgtac agggaacctt cagcagagtc caatgtactc ctgatctgct
     3661 gcctagtgat attcttggtt tttccgtata caattcacaa tcaaaagagt ttgaatttcg
     3721 tccgggaccg atctttacca cgatcttgtt agcagatgag atcaatcgta cgactcctcg
     3781 tactcagtca gcacttttag aagcaatggc cgagaatcat gcaacgatcg acaacaatac
     3841 ataccctcta gacaatcatt tttttgtctt agctacgcaa aatccaatcg agtacgaagg
     3901 aacatatcct ttgccggaag cacagctcga tcgtttttta ttccgactac aaatcggtta
     3961 tccttctttt gatgacgaac ttttgctact tttggataaa ttcgaaaaag tgttggataa
     4021 cttaaatgaa gtattgaaca gttatgaaat agaagaaata aaaacaaatg tggcgaatgt
     4081 ctttgtcagt cccgaagtgg catcttatgc cttgcagtta gtgtcagcaa caagaagtca
     4141 tgctgccatc cagcttggca tcagtccacg aggaagcctt tcctttattc aggcagcaaa
     4201 agcttatgct ttaatccatg ggagaaatta cgtcacgccc aaagatttgc aggatttagt
     4261 tccttacgtg ttttcccatc gcctgatttt ttacgatcgt tcattgaagg aagacgaaaa
     4321 gaaacaaatc attcatactc ttgttgcaca aattcctatt cctgtgaggt agattgaggt
     4381 agacaatgga aaaaatcaaa gattatttca ttaattttgt gttatttctg gtatatttca
     4441 tcattgtgct ttttgctctt gtattcaaca attctttagg ctggttcttg ttggcctttt
     4501 ttactcttta tgtatcatgg agcttgattt cattaagcag ctttctaaag aaactttcgg
     4561 ttacttgtac attgcagcca ctcgtttatc gcaaaaaaag tatgcaggtt attttttcca
     4621 tagcaaaaaa gagaactttt tctttacctc tccctcgttt acaaatcggc ttcccagcaa
     4681 tctttgcaga aaaaaacaag agattttgat tcttacaaat aaaccgcaag aagtccaatt
     4741 gctttggcag ccaaaagaaa gaggatgcca tgaaacatta actgtcattt ttacagccta
     4801 tgatagtcta ggacttttca gaaaaagtgc aaaaagagag atctcttttc ctgtgactgt
     4861 tctgcctgct ttttgtaaga ttcaagcaga aaaattacag agagttctgg aaaaaaaaca
     4921 gcagctgaac gcgtaccaaa gaggtcttga ttttcgggaa catcgcgctt atcgtccagg
     4981 tgattctttc aaccgaatcg attggaaatt gtctgctcat actcaagagt ggttataccg
     5041 tgaatacgat tatcaagaag aagaatgttc tcctcttttt tgcttttggg gttcgcccag
     5101 tccaaaattt gaacctctgc tagacttgta tttttcttta tggcatttga gaaaagaaaa
     5161 gcagccggaa cttctgatat taggcaaccg cgcctttcat ggcaaagacc ccggtcatac
     5221 ctattttgct tctttggaag ctggcgatga gaaagctttt ttcgcacact tgaaaaaata
     5281 tgcaaaaaaa caaatcgtcc tctttgttcc tgagaattct cctgaagtct cagaagctat
     5341 tgaaacattg tcaaaagatc gaacggttta tcttgtttat ttcgtagaaa aacaactcat
     5401 ggtccaagaa aaagacaaga tatgttcatt gccaggaggt gaatggattg acgattaaac
     5461 gggaaaaatg gctgcgtggc gtttactcct ttgtgatact aagtgtaggt gctccgatat
     5521 ttgtagtagc taatcaattg caaaacagct accttcttat cctaactatt ggtgtcctat
     5581 gccttattgt ctgctgtatt cctaaaaaat gggtacgttt gctgctttct ttgccagtaa
     5641 tgataggttg tttgttttta tattttcctt cgaagacatt ttccatatta tggatcttac
     5701 agtttttttc gtcagtcaca gaggaattct tccatctatc ccaaggtaaa ctttattatt
     5761 tgccagaaaa gacagctttt tttctcataa tgttgctgat ctatttattt attacattga
     5821 ccgtggatta cgactattgg tacgcaccct ttctttcttt gatggcttac ttcatgatgc
     5881 ttaccgtttt tcggaaaaaa gatttactgt acgaaatgat tgcggtagta actgttttgt
     5941 tcgtgtatct ggcagcaagg caatttttct ccatccggtt gttgtcggga aacactcgat
     6001 tccagtcatt gactacagtt ctgcttattt gtttcttaac ttttagcgct atcttgcctt
     6061 tatatcttcc gaaagtacac caatctctcg aggaaacgag tgaaccgatc cgagaatatc
     6121 ttaatgatga agggctttat gacacactcc atgagtatca attaaccgga agtgcaagaa
     6181 caggcttcag tgagaatgat gaacagcttg gtggaccttt atatgataat ggcgaagttg
     6241 tttttacagc gaaccaaaaa ggaaatggct attggaagat cgaaaataaa aatcattaca
     6301 ccggttctgg atggatagaa gatcaggacg cacccatcca accaatccaa gaattccctg
     6361 ttgacatcac gagctaccaa accgttatag aagacaaaga aaacattaca ttgaccctaa
     6421 aaaaacaagt tttcttacct tatccttatg gaaatactac cttgactgat ttttcattag
     6481 ctagtggaca aacgctttac tatttgcctg aaagccagcg attcattcct gtcccgaatg
     6541 aatcgacacg ttctgcaact ttacaaacag aaaggttagt ttttacgaga gaagaattaa
     6601 aaagcagtca gttaaaagct gatgatttag aaaatcagca gacaaatctt caattgccaa
     6661 aaagtttgcc taaacgtatt gaggacttgg cggtcgaatt gaccaaaaat gaagcaactt
     6721 taattcgtaa agtcgaagct gtctaacagt atttaaaaac aagcggaaat ttccgctatt
     6781 ccaaaacgga taccgggcat actccaaaag aacacgatta tgtggattat ttcctctttg
     6841 attcaaaagt cggctattgt gacaactttt caacttctat ggtcgtcctt cttcgaacac
     6901 ttggtatccc agctcgctgg acaaaaggtt ttacaaatgg gctcagaaca ggcacagata
     6961 atcaagggaa tgaggaatac agcattctca atagtcatgc tcattcttgg ccagaggtat
     7021 actttcctgg atttggctgg cttccatttg aaccaacccc ttcatttgcc aatccaatgg
     7081 gttcacaacc agttgctgaa acaaccgaaa ccgtccagcc tgctatcgaa caaccaaatg
     7141 aaagcgaaaa tatggcagaa actatttcca gtgagagatc tgaggtcatt ccatcagaag
     7201 aaacaacact cacaccagct tataaaatcg tcttattcag ccttggagtg tgtttatccg
     7261 tcttgttgtt ctttctattg ttattcagaa aatctctgcg ctggacaagt tatcttatct
     7321 atcttcattt ttttgcttct actaatacga ttgcatatca aaaacttctt aaccctttgg
     7381 aaacattggt accgcgcaaa cccgcagaat ctttgcagga atatagcctg cgaatagaac
     7441 aagaattcaa gctagatctg cgtttcattc gattaactac tcaatatgaa gcagaaatat
     7501 atggacgaca agcagatccg gtaaaattcg ataaaaaaac ctatttagaa ataacgcata
     7561 taataagaaa aatggtatac aaaaaaattc tgacaaaagg gagccgcttc aaaaaataag
     7621 ataaaatttc tggagaatct acttctggaa tgccgagaac cagctgattg agtatcgatt
     7681 actcgaaaaa aaggttgtga cacgtttttt gtcacaacct tttttcatta ttatctgatt
     7741 ttcaatgtca aagcatttag agctacaact accgtactta acgacatcaa gacagcacca
     7801 actgctggac ttaatatgat accaattggc gcaagaattc cggctgctag cggaattgca
     7861 agaatattgt aacctgcccc ccaccagagg ttctggatca ttttctttcg cgtttgcttg
     7921 gctagatcaa gaaaatgcaa aatatctttt ggatcgctgt ttgtcaatac gacatccgca
     7981 gaatcgattg cgatatctgt ccctgcaccg attgccatcc cgattgaagc acgggctaaa
     8041 cttggcgcat cattgatccc atcacccacc atgattactt ttttcccttg gtcaaggtat
     8101 ttctggacaa cagcttcttt atcatctggt aataaaccgc cataatattc ttcgatccct
     8161 aaataatctg ctactgcttg ggcagcgttt ttattgtcac cagtaagcat gacaggagtg
     8221 atttttcttt ctttcaatgt tcggataaat tcttttgctt ctgtttttac tacgtcacct
     8281 aaagcaacga ttgcagctag atgattttct aaaatcagga agctgatggt atttccttgt
     8341 tcttggtaag gtttcaataa tgcttgttct acgtttaatc cgagacgctc aacttctttt
     8401 tcattaacta ttttcacttg ttgttttttg actgttgcct ctagcccgac tcctgaaaga
     8461 ttttttagat tttcagcttg ataaggcttg atttcatgtt ctttcaaata attcataatg
     8521 ccaacagcca atggatgatt ggcattcgct tccaaggctc ctagatattg aaggatttca
     8581 tttttattga acgcatcatc aagtacttcg acacccgtta cagtaaattt tccttctgtt
     8641 agtgttcctg ttttgtccag catgatcaca tctagatcat tggcttgctc cagtgcattg
     8701 cggtttttca aaagtaatcc gtttttagct gctattgatg tggaacgagc aacaactaat
     8761 gggatagcta aacctagagc atgaggacag gcgatgataa agactgttac catacgttct
     8821 aatgcattag gaagatctgt caagaacaac caggcgatga atgccaggat acccacaatt
     8881 aatgcgacat aaaacagcca ttttgccact ttgtcagata atgactctag cttggatttt
     8941 tctccttgtg cttttcgcac catttccata accttcgcta gataaccatt ttcaccagtt
     9001 ccagttactt cgatttcgat cgttccatcc ccattgatag aaccgccaat cactttgtca
     9061 ttggcttgtt ttttgattcc tcttgattcg ccagtcacag ctgattcgtc aacaattgtt
     9121 tcacctttca agattacacc atctgttggc attttatcac cagaccggac gatcaaacga
     9181 tcaccttcgt ttacttcttt caatgaaact gtctcttctt ttccatcttt cgtcaagcgt
     9241 ttcactgatt ctggcagtaa ttctgctagt ttttgtaaag cattgctggc attcgacaca
     9301 gcattcattt caatccagtg acctagtagc ataataacga tcaaagtagc caattcccag
     9361 aagaaatcca tgacgtgtgt atgtggattg agcagatttg cgataaacga atagacacta
     9421 taaatatatg caactgtaat ccccatcgcg atcagtgtca tcatagcagg acttttttgt
     9481 ttcaattcca tcttagctcc acttaaaaat ggctgaccgc catagataaa tagtatagtt
     9541 gctaagatca atacgagcca atcagaacca ggaaacgtta cttgaaatgg aaattccatt
     9601 cccatcattg gtgaaaaaag aatgattggg atagctagga taagcgatag ccaaaatttt
     9661 tgtttgaaat tccccatgtg catggaatga tccatgccgc cgtgttcgtg atccatgtgc
     9721 atcgaatggt ccatttgttt gctgtttgct atatctccat ggttatgtcc catgtgcatg
     9781 gaatgatcca tctgactatg gtcatgtttc atctccatct gtttttcatg agattctgta
     9841 ctttctttgt ttactacttc ttttttatgc tcatgttttt tctccatatc gttcccattc
     9901 atttttactc catcccttct cttacttttt catgtgtcga tttaagcaca gggagttcaa
     9961 caatacactg acggaactaa acgccatcgc tcctcctgca atgattggat tcaaaaagcc
    10021 tagtgcggca aaaggaatac caatcgtatt atagacaaaa gcccagaaaa gattttgttt
    10081 gatttttctc aatgtcaacc tagacaactc gattgtttgt gcaatggatg ccaaactgct
    10141 attcatcagc gtcacatcgg ctgtttccat cgcaatgtcc gttccacttc ccattgccat
    10201 accgacatca gctaatgcta aggccggtgc atcattgatt ccatcgcctg ccataccgac
    10261 ttttttgcca tctttctgaa gtttttctac gtaggctgct ttatcctctg gaagtacttc
    10321 agcaaagata tgctttggat caataccaac ttgtttacca atcgtttcgg ctgccagttt
    10381 gttgtctcct gtcagcataa aaacatctaa tcctttattc tggagctgct tgattgcttg
    10441 tttgacttct agtttgattt gatcagccac ggcaatcaac ccgatcactt gcttttcatc
    10501 agctaaaaac atgactgttt ttccctgctg ttctaattct aacgcgtgtt cttggtattc
    10561 atcaaatgat aggttcaatt caattaatcg tttacgtgta cccgcaaaat agcgtactcc
    10621 gttaatcgta ccgctgattc cagcacctgg gtgggctgta aaatcaatca tatcgtatgt
    10681 tgctgcttct tgcagttttc cgtattccac gattgcttta cctagtggat gttcagaagc
    10741 ttgttctaaa gtataaaaaa tagataggac ttctttagaa ccgactagat ctgtaacttt
    10801 gggctttcct tctgtaatcg ttccagtttt atccaaaaca atgctgtcta agtgagcagc
    10861 tgcttctaat gcttctccgc ctttaattaa aattccattt cgtgcaccaa cacccgttcc
    10921 taccataata gctgttggag tcgctaaacc taatgcacat ggacacgcaa tgactaatac
    10981 agagacacta tggatcaatg cgagttgcca atcaccagtg atcaaacctg tagctatgag
    11041 cgtgataaac gcgatgacta atacgatcgg aacaaaaatc cctgagatcc gatctgcgat
    11101 tttttggatt ggggctttgc tcccttgagc atcttccacc atttgaatga tttgcgctaa
    11161 tactgtctgc ttgccgactt gtgtaacttc catgtgaagt agaccattcg tattgattgt
    11221 cccgccaaag agcgtgtcat ccggattctt ttctacagga agattttcac cagtaagcat
    11281 actttcatct atcgcactgc ttcctgaaat aattcgacca tctgctggaa tctgctcacc
    11341 aggacggatg actagttgat caccaacgac tacttcttca atcgctaacg tttcttcttt
    11401 cccgtttctt atcacttggg cggtttttgt ttgaagagac atcaattgtt tgattgcatt
    11461 acctgttttc gtttttgctg tatgttccaa atatttgccg agcaaaatca gcgtgatgat
    11521 catactgctg ctttcaaaat aaagatcttg ggggtgtcca cggaaaaatc cgttgtaaat
    11581 gctcaatgca aaggcagccg atgttccaat tgctaccaat acatccatat ttggtgcttt
    11641 cgtcttgatt gcatggtacg cacctttata aaaacgagca ccgacataaa attggacagg
    11701 agcagacagc actaactgga cgattggaaa atgaaaaaag tgaacaatcg ccgcatggct
    11761 tcctaacatc atagcaatca ttgacaacat caacggcaaa gtcaaaaccg tactcaatat
    11821 aagatcgaat agcatttttt tcaaatacgc ttgcttttct tctgcaattt tttgtttgtg
    11881 ggcttcatcg tacaaaattg caccatagcc gatgttttct acgctttgga ttaatttttc
    11941 agtggtcgtc ccttcatatt tgacacttgc tttttcagtg gccaagttga ctgtggcatt
    12001 gaccacacca ggttgtccgt tcagctcttt ttcgatccta gcagaacaat ttgcacaagt
    12061 catacctgta atgacgaacg tatccatttt ggtttctgct gttgccatca aatcacctct
    12121 gctttataac ccaatccatt gattgcttga caaatctttt cggattgaac ttttgtttca
    12181 tcaaacttga ccgtaccgtt tgcttttttc aaatttactt tcactttttg cacgccgtca
    12241 agtgcgctta ctgtttcttc tactcttgct gcacaatgat tgcagctcat accttcgatt
    12301 gaaaattgtt gtttcatttt ttcttcctcc tattgatgtt gtttacattc acattgacct
    12361 gggatacagt tacattcgat cgtatctact ggttgctttt gttccagttg tttcaaaatc
    12421 tcattgatat cttcttgagt caaagtggct tcttctacta gatccgcaat cgtctctcca
    12481 atcctttttg cacagatatg ggaaaaaaga ttttccgtcg cactgcgaac tgtttccatc
    12541 tccgagacag ctggataata aatgaatttt tttccttctt gttctgtcca gatcacttct
    12601 ttttttacca aacgacccag caaagttttg atcgttgctg gtttccaatc catcgaatca
    12661 gctaagatct gcgtgatttc ttgggctgtc gtctgtccaa gtgtccaaat aacacgcatg
    12721 atctcccact ctgaatcact gatctttact ggcgttttga ctttttccat ttatttcaca
    12781 cctttcgttt acaaatgtaa tcattatctt atgaatacag attacacttg taaacaaaaa
    12841 ctgtcaatta tttttgctct ctattttcaa tttagttaaa aattcttgtt tctctcgtct
    12901 tgttttaagg atgatcagtt tatttcttgc attagctact tggatcagct gctgtatttt
    12961 cggttcattg ttttcttcaa aatgccagat aaaagataaa aattctaagt attccctgtt
    13021 tagtttctcc gaaaatgatt caggcatatc tggccgagat tttttgttta tctttctttt
    13081 tagagaacgc caaactactc ggtagatggc gagataacgc ggcactttaa gccaaatgat
    13141 cttatctgct tctttaatcc tttcctctaa tgtagaagta taatttcctt caacgatcca
    13201 tgacggatta gataccataa acaattgctg ttcttgcaaa aaccactttt ttgcctgaat
    13261 actgtagtct gttgtatgcc ataaaaggtc tagcggcagt agcggaaagt cggtgatttc
    13321 tttgatcttc cttgcgaggg tcgattttcc cgacccactt tgtccaatca cgatgatctt
    13381 cattcttctc cctcacttct ctttggaatt tggttcgatc ataccactta taacgccgca
    13441 aaaaaacaag ggactgtgac aaaagtcgtg tcaaagtccc ttgtttcgaa taa
//
LOCUS       DADVXK010000074        13447 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.075, whole genome shotgun sequence.
ACCESSION   DADVXK010000074 DADVXK010000000
VERSION     DADVXK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.075"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            10..2382
                     /locus_tag="KB909_002038"
     CDS             10..2382
                     /locus_tag="KB909_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838048.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2443..3903
                     /locus_tag="KB909_002039"
     CDS             2443..3903
                     /locus_tag="KB909_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6838049.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3914..6118
                     /gene="topB"
                     /locus_tag="KB909_002040"
     CDS             3914..6118
                     /gene="topB"
                     /locus_tag="KB909_002040"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6838050.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6134..6283
                     /locus_tag="KB909_002041"
     CDS             6134..6283
                     /locus_tag="KB909_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838051.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6358..6951
                     /locus_tag="KB909_002042"
     CDS             6358..6951
                     /locus_tag="KB909_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBB6838052.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6964..7863
                     /locus_tag="KB909_002043"
     CDS             6964..7863
                     /locus_tag="KB909_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBB6838053.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7866..8363
                     /gene="ssb"
                     /locus_tag="KB909_002044"
     CDS             7866..8363
                     /gene="ssb"
                     /locus_tag="KB909_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6838054.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8729..8989
                     /locus_tag="KB909_002045"
     CDS             8729..8989
                     /locus_tag="KB909_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838055.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9434..9640
                     /locus_tag="KB909_002046"
     CDS             9434..9640
                     /locus_tag="KB909_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBB6838056.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9688..9891
                     /locus_tag="KB909_002047"
     CDS             9688..9891
                     /locus_tag="KB909_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838057.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9907..10344
                     /locus_tag="KB909_002048"
     CDS             9907..10344
                     /locus_tag="KB909_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838058.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10337..11044
                     /locus_tag="KB909_002049"
     CDS             10337..11044
                     /locus_tag="KB909_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838059.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11424..11603
                     /locus_tag="KB909_002050"
     CDS             11424..11603
                     /locus_tag="KB909_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838060.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11928..12191
                     /locus_tag="KB909_002051"
     CDS             11928..12191
                     /locus_tag="KB909_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBB6838061.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12185..12535
                     /locus_tag="KB909_002052"
     CDS             12185..12535
                     /locus_tag="KB909_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6838062.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12559..13173)
                     /locus_tag="KB909_002053"
     CDS             complement(12559..13173)
                     /locus_tag="KB909_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6838063.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT         4977 a         2209 c         2753 g         3508 t
ORIGIN      
        1 ggaaagaaca tggcagaaga aaaagaacca ctagacaata gtcgtttggg aaaatccaaa
       61 agaaaactag tacgattgca aaatgaatta aacgaacaaa ttgaaaagat gtttgaacac
      121 caaaaaatga cgaacggtca accaatgaac gacaagagga atggccgttc atggtttaac
      181 cagcaagaac gaatcgaaaa taaagtccaa agtctgagag aagagatcaa gcaacaagaa
      241 gaatacgtgg aaaagcttga aagacaagaa gagctaaagg aaatgggcta taacaagtac
      301 ggcggactgg atatgacgat cgataatatt ccaagaatca aagaagaaat cgaacgcttt
      361 gaaaaaggtg aatcggcttt ttcagccgcc acgatccgaa aataccaacg gaagttggaa
      421 acattagaac agctgaaaga aaaatcagaa aaaggaaaag aaaatatcct ccctgaagta
      481 caagcgatca ttgacagcgg acgagtgacg caatggaaaa aaaatccaac catttatttt
      541 ttgaaaggct atcgaaaagt tgctttagaa ctgaatgaaa acgggggatt tgaggaatca
      601 aaaaaatacc aagccacgtc ggaagaggaa aaagcagctg ttcgtgaatt acttgaagag
      661 gctagaccaa ctgattctat gaaggagaaa gaaaacgatc atttctatcg agtagaattc
      721 aacgaaaatg atccagaaaa aggattgaaa agttatggtg gggagatcgt aacattcgaa
      781 ttgatcgatc aactcaaaac attggataac caatacgccg cagaagcagg ttattataaa
      841 ttctattttg aggaagtgaa gaacggagaa gtagtcgatc agatccgaat ggatctaggg
      901 gatggcgtca acagtaatca accaatctat ttagagttag caaaattgtg cgaacaagta
      961 cctgagaagg aacaaaaaca atcggtcaaa aatgaacctg tttcgaaaga acaaatgcag
     1021 tcgaaagaaa caaaaacaaa acaaaagggc tatcaaaaac gaacggcaga agagattaaa
     1081 caagaagtta aatccctttc gcaacaggca ctggatgcgg tgaaaaagca tacccattct
     1141 cctgaagacg tcaaagaact tttgaacttt atgtctcgtt ttccagaacg atcctttaga
     1201 aatcaattat tgattgagga acaatttcca ggtgcaacgg cttgtttagg tcgtgccgcg
     1261 ttgaaaaaag aaggaatcta tatcaaaaaa ggggaacaag ggaacaagat ctttgtcaga
     1321 aaaacggtca aagggtttta tgagaaagga cgtggctttg ttcgagaaac agaagctaca
     1381 ccagaagata aaaaacgaat cgaaagtggt caaatcgaag tgatcaaaaa accttactat
     1441 acgattgaaa aagtgtttga tatcacacaa acacagttaa aacctgaaga ctatccgaaa
     1501 atctttccga accgtgtctt tgattttcaa ttggataaaa aaggacagtc agaacttcaa
     1561 gctgggattc aagcggtagc caacaatatt ggaatacaaa ttcgagatat gacagaaagt
     1621 gaagtctatc aaagagaatt aggacaagca cgtggggcgt atgttcgtaa cgaatttact
     1681 ggcgaagaag aaatcgtcat gaatactcga aatactccta cgcagcattt agctacaagt
     1741 attcatgaat tagcccatgc aagaatgcac aaattttcag aattagatac cgcaactaaa
     1801 gaattgcagg cagaaatgac ttcttatatt gtgtgcaaac attttggaat ggacacgtcg
     1861 gagaaagcta ttccttatat tgcagcatgg acgaagaatg gtcagacgtt ggatgataag
     1921 gaagctgcgg aacgtgggaa aatcatgaat gatgtcagcc gtgtcgcaaa tgaattcatt
     1981 caaaccattt ctaatgaaat caatcaatac agagaaagag aaccagagat ccaaccagca
     2041 gaagtgaagc aggagcataa aaatacttta gaaacgccag agaataagaa tattgtgccc
     2101 gttggttcac tttggatcga caagaaagac gggaaagtaa tggaagaaga tacgggtcga
     2161 acgttacatt tgaaggatgc ggcgtttatt gaagatccgc agcataatca agtaatttta
     2221 aaaggaaaaa gttatggaaa agagatccaa acggcgttac cttcagaaga atttgcgcta
     2281 ggaaatccat tccgattttc acttgagaca gtgtcagaag tggcaaaacg aaaaaatgaa
     2341 atctattatg aacaacaatt gtcacaaaaa gaacgtgtat aaaacaagta aaaaagacta
     2401 tctgaaaaac ggatagtctt ttttcttttg ggaggtttta aaatgaccga gaaaaaaatg
     2461 agtcttattg atcgatgtaa acagatcgat atagtggatt ttgctcgaaa caatggaatg
     2521 gctgtagtca ataaaggacg agattatcgc ttagaagacc atgattcatt tgtttttgat
     2581 cgaagaaaac aacgttttta ttggaacagt caaaatatta gtggcgacat tattgaatta
     2641 gctaaacttt ttttcataga caaagagatc caagacccta agcaacaatt taaagcagcc
     2701 actgatttta ttctaaagaa tgaagacaaa acagaacgag tggaaaatct tcattttgaa
     2761 acagaaaagt acaaagatca ccccgttgat tatcaaccac tcacagaaaa aggaaggaat
     2821 tatctgaagg aagaacgaaa actaccagag tggctgattg attatgcaga aaaagaaggg
     2881 ttgattgccg aactaaagcc aaaatatgaa cggcaaaatt tcttagttcg agacgatcgt
     2941 ttagatcatg cggtcgcctt tttatggaaa gatccacaga caaaagagac agtaggggcg
     3001 agttatcaag gaacgttcat tgattatgaa cgttttggtg agagaggcac atataagcat
     3061 atagataaaa attcgacagc gaatcatggc tttaacctaa agatcggtga ccctaagcag
     3121 ataaaatttt ttgagagtag tattgattta cttagctatg ctgcactgaa tcgtgatcag
     3181 ttaaacgata cgtggttagt ctctatggaa gggttaaaac accatgtgat cagtcattat
     3241 tttggtgagg cagtatctga attgagaaag aaacaagcct ttcctcaatc catcgagatt
     3301 tgtgtggata atgaccgtgc aggacatatt ttctacgaaa aagaacaatt aatgggcgca
     3361 gtcgatccat ttacgaatca gaaagtacgt tgtgaacgag gaatcgctaa tgattggcaa
     3421 gtgccaaaag aatacaaaat catttatgaa gaagtcgcaa aagaagaaaa ggtcacacca
     3481 gaagctatta tggccataca caagacagaa aacaatctgc aattaacgaa ccaactggtt
     3541 tccgctcaca aagtaaatgc gttttttggc cagcagcttt ctgttaacga ttcaatagaa
     3601 gccattaatt tgaaagatat ttgtagagaa gtcgcaaaag aattaaaagt ttgtgaacgc
     3661 gtggatggta cgtacgattt tgatcgtttt tatcaagaaa aaggggatat taatgcgcag
     3721 attcttttct cttataaagc agaacaatac tacaaaggct ataaaaatca tgaacatgaa
     3781 tttgtacctg aagtaaaaaa ggactggaac gatcaattga agcatgagat ccagcaacaa
     3841 gaaatcagaa agcaaaaacg tgccatgttg tttcaacaag gcagacaaca agaaagggag
     3901 tgaaatcgtc atgatgaaaa ccgttatttt agcagaaaag ccgtcacaag cgaaagctta
     3961 tgccgatagc ttctctaaag ccactcgaaa agacgggtat tttgaaatcc aagatcgatt
     4021 gtttcctggt gaaactgtga tcacgtatgg ttttggtcat ttagtcgaat tagattcgcc
     4081 cgatatgtac gatgaaaatt ggaaacaatg gtcattagaa catttgccta ttttccctac
     4141 acattatcac tatcatgttc ctaaagataa gaaaaagcaa ttcaaggtgg tgaaacagca
     4201 acttcaatcg gccgacacca ttattattgc gacagatagc gatcgtgaag gggaactgat
     4261 cgcttggacg atcattcaac aagtaggcgc cgatcaagga aaaaccttta aaagactttg
     4321 gatcaactcc ttagaaaaag aagccattta tcagggattc cagcagttac gagacgcaaa
     4381 agagacctat ccaaaatttg aagaagcaca agcacgtcag atcgccgatt ggttaattgg
     4441 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagctt
     4501 ttccttaggc agagtccaaa ccccaacgct ttacatgatt tatcaattgc aggaaaagat
     4561 tagaaatttc aagaaagaac cttattttga aggaaaatcc gaagtaatcg ctcaaaatgg
     4621 cgcatttgat gcgaagcttg atccgaatga aacccaagcg acgcaagaag catttgaaga
     4681 ttatttaaaa gaaaaggggg ttcaattggg aaaacagcca ggcatgattc gccaagttga
     4741 aaccgagaaa aaaagcgcgg caagtccacg tcttttttct ctatccagcc ttcagtctaa
     4801 aatgaatcag ctcatgaaag ctagtgccaa agacactttg gaagccatgc aaggcttgta
     4861 tgaagggaaa tatctaagct atccgcgaac ggatacccct tacattacgg aaggggaata
     4921 tgcgtatctg ttggatcact tagacgaata caagcatttt ttgagggctg aagaaatttc
     4981 gactcctatt catacaccga atagtaggta cgtgaacaac aagaaagtcc aggaacatta
     5041 cgcaatcatt cctacaaaaa cagttatgac agaagcgacg tatgaaagtc tgacaccttt
     5101 acaacaagcg atttacgagc aagttttaaa aacgacagtg gcgatgtttg cggaaaaata
     5161 tacctatgaa gaaacaacga tcttgacgca agtccagcag cttcagttaa aggcaatcgg
     5221 aaaagtaccg atagatctag gttggaagaa gttatttggc aaagagagcg acggaaaaga
     5281 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtagatct
     5341 acaagtcctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     5401 tgcgatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     5461 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     5521 ggaatatatc aaggtagaga aaaataagct tgtggtgacg aataaagggg ttttgctttg
     5581 ccaagctgtg gaaaaagagc cgctgcttac gagtgccgaa atgaccgcca aatgggaaag
     5641 ctacttgtta aagattggag aacgaaaagg aacacaaacc acttttctag ccaatatcca
     5701 aaagtttgtc tctcacttat tggaagtcgt cccaggacaa atccaatcca ttgattttgg
     5761 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     5821 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     5881 gtctgaagcc tgtgatttta aattatggac aacgattgcc aaaaagaaac tcacagcgac
     5941 acagctgaag gagattattc aaaatagccg aacaagccaa ccagtgaaag ggttaaaagg
     6001 tcagaagggt tcgtttgaag caacgattgt tttaaaagaa gacttcacta caggctttga
     6061 attttctgaa aagaaaaaaa cgaacttcaa gaaaagaaca cgacgcacga caaaataatg
     6121 gagggttaat cttatgcgta atacaacaca caaacaacaa gaaatcgaaa atcaaaaagc
     6181 caaaattcgt tcagaacaag agaaattacg tgccagtaaa agaagacttc agcaattaaa
     6241 gaaccagcaa cggattcaaa aagaaatcga attagatcga tagacattaa ccttgttaca
     6301 aatacactat catgatatat ttaatgtagt gtatttgtaa caaaaggggg gaagtaaatg
     6361 caagagaaac tgaaagaatt gttggctatt cgcgatggaa atttatctat gaaggaagcc
     6421 agaaaattag gaatcgcagc aaccactgta caaagattgg tgaatcaagg aaaattgatc
     6481 aaagttgatc gtggttatta tgtagaggat ggtcatggaa tagatgattt attttggctt
     6541 cagcaacgtt tttccagggg aatcttctct catgaaacga ctttagatat ttaccagctt
     6601 tctacgaata tgccgaaatt cattcactta acttttcccc atggatataa cgttgatcgt
     6661 tcaattacaa aagagcagca gttacaattt catttcgtga agaaagaagt ttatgaacta
     6721 ggaaaagtag agggaacttc ctttcaagga aatcctatta ctatgtatga taaagagcgt
     6781 acactttgtg atatttggaa tccgagatat gaaattgaat atgaaatgaa attagaagca
     6841 ttaaaagagt acatggaaga cccattgaga gatccaagta aattaagaga ttacatgaca
     6901 aaactacatg tagaaaaaga aatgaaatac cacatgcaaa gcttatattg atggaggaaa
     6961 aagatgacac cgacacaatt tgcagcaaaa acaagaaatt tagcaaagag gacaggatta
     7021 aatgcacagt tagtacaacg gcattttatg atggatcgtt taattgaaca aatttctgaa
     7081 tctaagtata aaaatgattt cattttgaaa ggtggctttt tattaggatc aaaatatgga
     7141 atcgatagaa ggacgacaat tgatatcgac acgacattta gaaatagcaa attaactgaa
     7201 gaaaaattga agagtatttt taatgattta actaggaaac ccacgaaaga aggtattgtt
     7261 ttctctattc aaggaatgaa ggaaacaaga gaagccgatt tttatcctgg atttcaaatt
     7321 aaattggtgg ctaatttaga gaaagtacgt gtgccattta aaatggacgt gacaacagga
     7381 gattctattt atcctgaagt agatacacac tatcaccaat taatgtttga agataaaaag
     7441 gtggagattc cagcttatcc aacagcacaa attattgcag aaaagctaag tgctacgttc
     7501 agctttggca cagataattc gagagcaaaa gattactacg acttatttac cattccgaaa
     7561 ctagaaaata tcgatacgaa agagttatac aaaagtgttc gaaatacatt tacaaaacgt
     7621 ggggatacaa aaccgttgtc cttttattat gaaagagaaa tggataagat cataggaaat
     7681 gactatttgg aaaagcagtg ggaaaaatat cgctcagtta acacgtttgc gaattccatt
     7741 tcatttacag atacagtcaa cgaaattgat cacctaatga aaagtgtgat caaaattgaa
     7801 aatcaagaaa gaaaacggca gtttaaaaga tcacaacaaa tgaatcaaga aatggagaga
     7861 taaagatgat caataatgta actttagtag gacgcttaac caaagatcca gatttacgtt
     7921 ataccgcgag tggtactgca gtagcgactt ttaccctagc tgtcaaccga aatttcacga
     7981 atcaaaacgg caatcgagaa gctgatttta ttaactgtgt gatttggcgc aaaccagcag
     8041 aaacaatggt gacattagct aaaaaaggta gcttgattgg tgtagttggg cggattcaaa
     8101 cgcggactta tgacaaccag caaggacaac gtgtgtatgt gacagaagtt gtggccgata
     8161 atttccaact attagaaagc aaagcagcga cagaaagccg tgcgcacgct gatcaatcgt
     8221 ccaccagtcc aagcaccacc acttttgaac aacgggatac agcgacgcct aataacaatg
     8281 gattgaacgc tttacagaat ccatttggga atccatttgg tggacaatca atcgatatta
     8341 gcgatgatga tctaccgttc taagtagcat tttctattgg ttgcatttgc tacggtttat
     8401 gttataattt agtcaacaaa aagaattttc aatctataac caaaaaccac tagctggcgg
     8461 gctagtggtt ttcttttacg tttctattat aagaattaac gggtaggctt actgtctttc
     8521 ttggcaaatt tacaatcaag ccatttgcag atatagtgcg cggctacttc tgccatgatt
     8581 gcaaaaacaa aatcaaaaag aattttcaaa cctataacct cctccccttg ccagattagg
     8641 ccggggtagc agacagcaag actattatag cataattgaa atatccaaat gattggattt
     8701 ttgctataat tttagcgagg tgattgtgat gaacaaatat gttggtttgc ttgataaaat
     8761 ccgagtaata aaaacgcaac cgttattggt tcgctttact ttacaaacga ttcatgaatc
     8821 gattaattgt gtagttgcag atattgaaat tatcgataaa ttgctaatta tggatgatgg
     8881 aaaatacaat attgccgtca caggtcactt caataaacga aatcagctag ttattgctag
     8941 catgtatgtt agaaatcccg atcattttac gcgatcgatg ggcatataaa aaaagaagag
     9001 ttgcaatcct aatgtaggac tgcagctctt tttgttttac atagaaacaa gaaaaatgaa
     9061 aaggcctttt taggaaggcg cgagcgcctt ctcaattgaa aaacctctct cactccaacc
     9121 gccaccgccg ttcgagaaga aaggaagtga acgttgcacg ttcactaaga taaagggtct
     9181 tgcaaagcaa gacaaaatag aaaaaacttc ctctcaccaa aaggttcgtt cctgttcgtt
     9241 atctctttat tgatttgcca gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa
     9301 ggacaagggt aaatggcacg ctgcgcgccc ttgtccttgt cgcttttcgt tgattcattc
     9361 tggccaacaa atcaataaag aaagaactaa cgaaaggaag taaaaccttt cctaagagga
     9421 ggcagaatca atcatgcgaa agaaatttga ttattggggt gttcccttca gcgaattatt
     9481 cccaaactat catgcaccac atactgtcga atgcgattgt ggacaaagag cgaaatgtat
     9541 caaaagctat cgtttgtatc aatgtccaac atgcggaaaa aaatacacct tgtcttatgg
     9601 cgattatatt ttgattgatg agaaaggaaa gaaacgctga tgaaaacata acataaatta
     9661 ttgactgtaa aagaagtcgt tcaaattttg gtggacaaag aagtcatttc tgaaaaagta
     9721 gcagaagctt tacttattcc gcggtactgg acgatagaaa cccctttagt agaggatgca
     9781 ccgactatgc tatttgaaga cctagtgaag attgcaggat atgaactgca ttatcaagaa
     9841 aacatggaaa cttatgaaaa cgaatattgg ttaaccaaat tagagaacta aaaaggagaa
     9901 aaaaatatgg ctcaaaatta ctatgacgaa tttgtcaaat tacctttgga taaaatggca
     9961 caaaaaatgg aggatatgac attcctatac catgagacac gtgttccaaa aaaacattat
    10021 aaggaaagat tgtcggtagc tgtggaagaa atgattgaat caggtgtcga aatgaatctc
    10081 attgcgacgt actatcgaac actggaagaa ctgaaaaaac aaaatgcaaa atggtttttc
    10141 caagccttac tatgcttgga agtaggtgtc aaaccaagca ctattaaacc ttctgaatat
    10201 caagctttag aactaacgta tgggaaattt gtcgaaacga aaaaagccaa gactgtttca
    10261 agtgaatggt tagattattt tgaaaatatc aataagtatg gcgcctatta caccatgaaa
    10321 aaggaggaca acgaaaatga ataaggtgat ttatcaacta acaacggaag atgtgtcaca
    10381 ctttttaaca aacaaagaac atttgaatga agtaatcaga cggattcaaa aagactttag
    10441 ttgtatggaa gaaatgaagt actttattca aagagtcgaa gaacaattgt atttggaaag
    10501 tgaaacgagt caaacgaagg tcacagtcag caataattat ttagacgtgt ataaacatcg
    10561 tcctgaaacg gtaaaaaaag gaacggagct tctacgacta gaaacagaaa aatacatcat
    10621 gaatgtttac ctagaaagga gtgaactggt cgaaaacttt gtcagctgca cgatttgcag
    10681 gaaacactat tactcagaat cagaatatta ttcaattttt gagagcatgg aattaatgga
    10741 agaagaaatg gaagagctaa acagcaaaaa tgcgacgata gacgattatt atcttgtatt
    10801 tactagattt ttgacgtgtg gaacggaatc tatcgtgtta atgggaatgg attatgaact
    10861 cgctgtaccc gaagcatttt tgagggaata tgtagaagaa gtagataacc caggcgacga
    10921 ctggtacacg actttaactg attttttaga tacctacact tacgacgata cagaagaaat
    10981 ccaaaatgaa cttgaccgta aacgaatgcc atatcaacga tttgaaagga aaaaaaggca
    11041 ataatcattt ataccgaaaa gtgagaatgt gtgaaataag aacaaaaacc ttgaaattaa
    11101 gggaatggtt cttatttcgc accaatcgct ccaaccgccc ccgccgctta ggtggtgcga
    11161 aataagcggg caaagcccga taacctaaga gaaagaagga gatccatatg aataaaatca
    11221 ttcctctgtt gttcgtactg tgtattggcg agatacttat gcgtcatggt gcagctgtac
    11281 atttaaactt cgtagtattc ttaggaatac tagtattttg tttgattttt tggcgctttg
    11341 tgttagccct tgtgagtcta ctattcaagt tgattgcagc catatttttc atagggttat
    11401 ttcgatgaaa ggagagagta ctaatgccaa ttgcaatagg aaataaacgg ttacccgtga
    11461 cattagatga aaagagacaa aaagaattgc agcaactaaa gcagaagtac ggaaaaagtg
    11521 aatctaagat tatgtgtatt gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg
    11581 atataccagc actaaaaaag tgacgtcact tttcatttga agaaacaaaa gtgatagcac
    11641 ttaattgttc ctactattta gaatattttc tatgtccttt ttattccatt ttgtatcaat
    11701 aactatgaaa tctttaaagt atccagatca atttttttct tacctgattc taaagatttt
    11761 gttttcttaa acatattatg atttcctttc gactattttc atataaatgt taacatagtt
    11821 tatggattca tggaatgtta atctaattta atagaaaagg ataattaagt atatacgttt
    11881 tttcttatgt atgttatact atgtatatac agaaagaggt gtctactatg gaaatgttac
    11941 ctataaaaaa atggggaaat agtaatggcc ttagattgcc aaagtatatt atggaatatc
    12001 ttggaattca tacagaagac aaagtgaaga taatacaaga agaagtaaac ggtcagaagc
    12061 ggctaattat cgaagcggct aatatagaaa atgaattaac aattgaacag ttatttgaaa
    12121 attacactga tgaaagaaat catgtgacga ttcaaaattt aggtgaagca gtaggtaatg
    12181 aaaaatggtg agaaaaccta gacaaggcga tattctatta ttgaatacag cacctcgatc
    12241 tggacacgaa cagacaggta aaagacctta tattgtttta agtcatgata ttattgcgga
    12301 ttatagtaac gttgttacag ttgctccaat ttctagtaca actagaaact atccgctata
    12361 tgtaaatata aactcagaat atgaaatgaa gacaacagga aaagtattat tagatcaact
    12421 aacgacaatt gattatgaag ccagagagtg tatttttttg gaaaaagcgc atgatagttt
    12481 agttgaggag ttattgatga aagttagaac agtttttcaa aaagtaagca aataaaatag
    12541 aaacagcagc atgatcaact attcgtgatt gaccatgctg tcttttttta ttctatatac
    12601 ggtttgtctc gtaacattgt agtcttttgc aatcttagcg atcgcaacac ctttttttag
    12661 atcctcaacg atgtttttat aaacaagacg acgttgggga tcttttgcat tggcactgta
    12721 tagcttagga cgtcctttat aaacaccgtt cgcttttgca atcttaatgc cttgtgcctg
    12781 acgtcgttta gattcggtac gttcttgttc agcgatcatg gccaaaattt gaatgatcaa
    12841 atctttaatg aatttatcca ggagaggatt gccaattgct tcggccatga tcggtagact
    12901 tgtgatgatc agctgcacat ttttcttctt caagtaattg actgaagcga tgatctcgtc
    12961 gtaatttctt ccaagtcgat caatagcttc cacaataaaa atatcttgat ctcggacgaa
    13021 atccagtgct tcttgaaaaa caggtcgatg agtaatcgtt gcgccagatt gtttctcaat
    13081 gaaaattctc tctgcaccga attttttcat ttcttcaatc tgccgttgtt cattttgatc
    13141 gatggatgag acacgtatgt atgcaactct caaaattttt acctactttc tgcaactatt
    13201 taaaaaacac cctaatcata cacgagaaaa ccagattttt caatgtcgcg gtcgtgtcta
    13261 gttagggtat accttatata gacaaaaact aatgatggag gaaatagtat gtgtcacttt
    13321 tctttttaaa tggcaatatt ttttgtaaat aaatgtcaat caagaaaatt taaacgatta
    13381 tgacattaaa aatatatttt atgaattttc tagtatataa cttgatttat ctgttaagat
    13441 ttattaa
//
LOCUS       DADVXK010000075        13240 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.076, whole genome shotgun sequence.
ACCESSION   DADVXK010000075 DADVXK010000000
VERSION     DADVXK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.076"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..173)
                     /locus_tag="KB909_002054"
     CDS             complement(<1..173)
                     /locus_tag="KB909_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6838064.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="KB909_002055"
     CDS             complement(593..1714)
                     /locus_tag="KB909_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBB6838065.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="KB909_002056"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="KB909_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBB6838066.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="KB909_002057"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="KB909_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBB6838067.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="KB909_002058"
     CDS             complement(4304..5215)
                     /locus_tag="KB909_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6838068.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="KB909_002059"
     CDS             complement(5232..6239)
                     /locus_tag="KB909_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6838069.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="KB909_002060"
     CDS             complement(6236..8365)
                     /locus_tag="KB909_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6838070.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8513)
                     /locus_tag="KB909_002061"
                     /pseudo
     CDS             complement(8370..8513)
                     /locus_tag="KB909_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(8666..9853)
                     /locus_tag="KB909_002062"
     CDS             complement(8666..9853)
                     /locus_tag="KB909_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBB6838071.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            complement(9946..12291)
                     /locus_tag="KB909_002063"
     CDS             complement(9946..12291)
                     /locus_tag="KB909_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6838072.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLENGITSI"
     gene            complement(12278..12667)
                     /locus_tag="KB909_002064"
     CDS             complement(12278..12667)
                     /locus_tag="KB909_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6838073.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            complement(12717..>13240)
                     /locus_tag="KB909_002065"
     CDS             complement(12717..>13240)
                     /locus_tag="KB909_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6838074.1"
                     /translation="SGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDLVVIRLELNG
                     KKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVRSIITKKENR
                     QILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTVMEGGEDAFT
                     NRAKRYGFKQIVE"
BASE COUNT         3994 a         2754 c         2288 g         4204 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttttcagtca agtccacaat cttgtgtaaa
     8521 agttcaacct catcaaaagc acaatgtttt gcgttgtgaa cctaactgcc atgcctttct
     8581 ttctgaggag agaggtcagg agcagtagcg cagcgactct tgatgtctct cctcagaaag
     8641 aagagactcg cacaggttca tggtgctaaa tgttattcga attaaattct aaatattttc
     8701 gtggagaagc cagccactca gtgtcttttt ccatcaaaag tgttccaatt atccgagtga
     8761 tggaattgat atttggaaaa atccgaatca ctcgttctct ccggcgaatc tcttcgttca
     8821 accgttccaa cacattggtt gtacgaatcc ttcggcggat attttcagga aaagacaaaa
     8881 tttgaatagc atcttcaaag ccgttttcta aaatgtcgca agcagcactt aattttgaat
     8941 cacaaccata tttttccaag aagtgctctt ttctttcacg tgtcaattca agttcagagg
     9001 ctttaaagat actcttcaac tcgtctttta catcagaaga aactttcttt ggcagcttat
     9061 caaaaatatt tctcaaaaag tgggcttggc atctttgcca gctcgcacct aaaaagttct
     9121 tgcgaacagc cttaactaac cctttgtgtg catcagaaat gaccagtttt acaccgaaca
     9181 aacctcgttg aacgaacgat tgaaaaacgg tatcccaatt atcttccgat tcgccgtctt
     9241 gaacatcaaa accaagaatc gtacgtcgtc catcagaatc aatgccgata ccaatatata
     9301 caccttttga gacaatacga tgattttccc ttactttcat atacagggca tcacacatga
     9361 aaaatggata ttccgagcct tctaggctcc ggtttctcca ctcaaaaaca aatggatcca
     9421 actgtttcat cagatttgaa acgaatgatt tagaaacagt cgcaccatcc gttagcagtt
     9481 caactgtttt agttactttg cgagtggaga caccagaaat gaccatttca atcatggcag
     9541 cgatcaaagc tttttcgctt cgctgatatc tttcaaagat agtaggacta aacttaccgt
     9601 ctctggttcg tggaacatga agttctaacg taccaattcg agttgtaaac gaacgatcgt
     9661 agtaaccatt tctttgtgat tgccgttctt ctgaacgttc ataggcattt gcctgaatat
     9721 attgatttcg ttgttcttcc atcagctgat taaacatgat agtcataagt gtttttgcgg
     9781 tatcattcgc accgctttcg tttataattg cttgaatttc ttcgctttca aaagtaaaat
     9841 gtacttgagt cattgatatc agtcctattc gagtatgttt tctgcaaaaa acattgtact
     9901 cctaactgag atcaatggct tttttgatgc ttcactttta cacaattata tggacgtaat
     9961 cccgttttcc aaatctcgca ggcgtttttg attgctttga tcctcctgat ccaaaccaaa
    10021 gaattccaag gttttcttga tttcatgaat atcggtactg cgaaaagcaa acttcaaccc
    10081 gatattattt tttaaacgtt catctaataa atcgtcgcta ttttgagtga cgaaatagac
    10141 cccagcattc atggcccgac cagcacgaac aagcttattc gataacgttt ttccttgagc
    10201 cacttgaaga aaactccaag cctcatccaa atcgacaatt ttgaagattt ctcggttact
    10261 atggataaag tccaaggcaa aagtggaaat gacgattagc atcgaaacac taagcaattc
    10321 catggtggta tattcttcaa aagtcgtttc tgcatccggt aaaaccaaat ccgccacttg
    10381 aatgatattt agctgtttat ctaaactaat cgattgggta atcgagccgt ctgagaaaag
    10441 caaatgagca aaatcataat cggtaaagga ctcgatatga tcggcgatat tttccgcgat
    10501 tggtgacccg tcttttcgca attcgttaat aacttgtaat aacccccgtt gatcactttg
    10561 agtcaccgtt cgaatggctt tacgtaacac aggaaacttc tccccgtctc gacttgaaat
    10621 tcctgttaaa aaagtcagaa tatcaattgc taaactttcc gagtctttct ttttcttcat
    10681 aatcacataa ggatcaagca gaccttgatt ttctgactta ctcgtcaagt tgaggatact
    10741 gatttcatcc gcaatttctg gcaaggtttc tttccaccct cctcgctccc cttttggatc
    10801 gacaatcaca gcttgaccac cgaacaaaac agcatagtag actaagagat tgttactaaa
    10861 ggatttacct ccaccaagag aacccaggaa agcggcggcc agcgcattgg ttactgaacc
    10921 cttgactcct tgtgaagcca atgccggttt caggtaaaca ttacgacctg tatccacatt
    10981 gtagccaaag taaatccctt ctaattctcc tagcatctga gtagccccaa aaccaagccc
    11041 cgccaaaaaa tcagacgtaa catactgaat atagtcgttc atatatcgtt tacttgaggg
    11101 taagaattct tcatgtagcc ccatcatatc gccaaagggc cggactagtt ttacattggt
    11161 atcatcataa aaatcgagca cttcatcaca gcgtcgcttt agttcatcca ctgattcggc
    11221 actcactcga accacataac tcagtttgta catagattct tttgactgat ccaaggtggt
    11281 ttccaattca tccacggaat ccaaagcatc taagacattg gaattcgttt cattgtcaga
    11341 ttggtaagca tgattgtcta aatctttcag ttcttttttc ttattacgaa cggtagctaa
    11401 agccttttta ttcgtcacaa tctctacatt catacttgtg tcgattggga atgtaaattg
    11461 ttgttgctgg taatagaaaa gttctgagga aggaaattcc atctccccca caattgtatt
    11521 aattgttaaa tacgctacgt acgactcatg attctcatgt tccatccgta agcaccttgg
    11581 tttttcttca attaaacaac gatttggacg taataagtca taacgtttca ccagtgtttc
    11641 tgattttagc tttttctttg gtagctgaaa ttcgtattct tcaaacggta tccctttttc
    11701 gccataaata tgttcaatca aatacgtcag gtcactcggt gtgactcgcc tgactttaaa
    11761 tcttcgagcc aatttgcttt ccattaattt ttcaagctta gaatagcagc gaatttcttc
    11821 attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga caaattcttg
    11881 aagcccagaa aagaaagatt tcttgagact ctttagattg acttcttcat ctgtcgcaat
    11941 tagtttaaag ccaataaaaa agcgataatc aatctgacta tcgccaatca tggatactaa
    12001 tgcatctgtc tgtatatcaa ttcgttgttt cgctacttct ttgagtctac cggtaatttc
    12061 tttttttgat cgttcttgtg tggcgcgaat actactttct gtggcaattt gtaacgcatg
    12121 gatcttgcct tcacgatttt gcgcaattag ttggcgaaag ttatcatgca cttgaaattt
    12181 ctgttcgggt gacaaaaagg agtaattgta aggcactaat tcatagtagg caaaacactc
    12241 gccttcttgg ttaaagacga gattattttc aatatactta atcggataca tagttcacac
    12301 tccttacaag agtactgggt tcatcccatc gtttcttctg ttctttgact ttctttcctg
    12361 caaaagtcac cttaaatcgc aagtgatagc tgataaagga tcgtaaaaat cccagtggtt
    12421 tcttgccatc aaacgtcttt tgcgacataa accaagtgac agccaccggt atgcctaagt
    12481 attttaaaaa gacctcctct atcatagata gtggaggcac atgggcaaat acgatgacaa
    12541 acagtaaaga taaaacgaac caagccattt ggttaaaagt cacaggaaaa ggcaactgaa
    12601 aatcattgat tgcgtaaatg actttttcaa ctgcccagat actggtatag ctttttattt
    12661 ttttcatttt tcctcctaaa aagggcggac ataataatat gtctcaccct ctagtgttat
    12721 tctacaattt gtttaaaacc atagcgtttc gctctatttg taaaagcatc ctcgccacct
    12781 tccatcacag tacatattct tggcttgata ttgggttcat ctaccgaccc gcactgatca
    12841 gccgatattt cttttgaatc tcccatgcta atcaaccatt ctgaatcacc attaactggg
    12901 atatttgcat tatgagttac aattaaaatt tgtctgtttt ccttttttgt aatgatactt
    12961 cttacgatta agttattaat taattgacta tccaaatcat cttcaggctg atccaatatg
    13021 agtggtgaat ttccatacgc caaaatcata gaaagaattg cagatgtctt ttgaccagca
    13081 ctagcattcg ataaactaac tttttttcca tttagttcaa gtcggataac tactaaatca
    13141 tttggcttaa gggtttgtaa ttcaagaact tgtgcatcat tcaattttct tatagaattg
    13201 attaattttt tatctgaaaa aatactactt tccccactaa
//
LOCUS       DADVXK010000076        13179 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.077, whole genome shotgun sequence.
ACCESSION   DADVXK010000076 DADVXK010000000
VERSION     DADVXK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.077"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            94..1545
                     /locus_tag="KB909_002066"
     CDS             94..1545
                     /locus_tag="KB909_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBB6838075.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            1894..2526
                     /locus_tag="KB909_002067"
     CDS             1894..2526
                     /locus_tag="KB909_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBB6838076.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3114..4553
                     /locus_tag="KB909_002068"
     CDS             3114..4553
                     /locus_tag="KB909_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838077.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4848..5066
                     /locus_tag="KB909_002069"
                     /pseudo
     CDS             4848..5066
                     /locus_tag="KB909_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5315..5530
                     /locus_tag="KB909_002070"
     CDS             5315..5530
                     /locus_tag="KB909_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838078.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5747..6003)
                     /locus_tag="KB909_002071"
                     /pseudo
     CDS             complement(5747..6003)
                     /locus_tag="KB909_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6190..7101)
                     /locus_tag="KB909_002072"
     CDS             complement(6190..7101)
                     /locus_tag="KB909_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6838079.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7120..8124)
                     /locus_tag="KB909_002073"
     CDS             complement(7120..8124)
                     /locus_tag="KB909_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBB6838080.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8121..10244)
                     /locus_tag="KB909_002074"
     CDS             complement(8121..10244)
                     /locus_tag="KB909_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6838081.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10249..12696)
                     /locus_tag="KB909_002075"
     CDS             complement(10249..12696)
                     /locus_tag="KB909_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6838082.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12683..13072)
                     /locus_tag="KB909_002076"
     CDS             complement(12683..13072)
                     /locus_tag="KB909_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6838083.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
BASE COUNT         4054 a         2536 c         2435 g         4154 t
ORIGIN      
        1 aagaaatata ctgtattact caattcattg aaaatattta tcataatttt taatagaaaa
       61 cactattaaa gagaaaaaag agaggtaaat caaatgaaaa aatctttaaa acttgcatca
      121 gcagttatat taatgtccca actccttata gcaacacctt tccatgtgtt ggcaagcgaa
      181 aattcaacat acaaaattgc aaaagaaaga accgagacga ctgaaatgag taattccgat
      241 gtaacagcag agagtagtga acttttgaca acttcatcaa gtgaaagtag tacgacttca
      301 aatgccgagt cttcaacaac ttcatcaagt gaaagtagta cgacttcaaa tgccgagtct
      361 tcaacaactt catcaagtga aagtagtacg acttcaaatg ccgagtcttc aacaacttcg
      421 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
      481 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      541 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      601 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      661 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      721 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      781 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      841 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      901 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      961 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
     1021 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
     1081 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
     1141 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
     1201 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
     1261 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
     1321 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
     1381 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1441 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1501 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1561 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1621 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1681 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1741 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1801 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1861 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1921 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1981 aatgaaacga ttgtatatcg atcaaactta ctatcaggta gaaccaaaag ttgtggatgt
     2041 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     2101 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     2161 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     2221 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     2281 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     2341 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     2401 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2461 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2521 aaatagattg cgtatataac tttaaaaaaa aagaggtact atttaggatc gtatgattct
     2581 attaagagtg cagctcaagc tagaaaagat gctgaaaata aattgtttca acctttgatt
     2641 gacaaatatc gaggtaatca ttaattattg tggataataa ttaacagtga tatataaaca
     2701 tctataatat attattcata ctattgatat ttagtataat cctatggaat tgaatatcat
     2761 agcaatgtat ttgaaaagca aattggaaaa caaataggtg caacaccata aatatgaaaa
     2821 aattgggaaa aagtagaatg gaaatttgct tacgtctcac gagatagctc acactattaa
     2881 tctgaagaac aatgaagtcg acttttagaa attgctagaa gaaagtaaag cgaattatca
     2941 ctagttacta tagagtaagt tcaaataaag catctccaac ttacatggtt acatgaggat
     3001 atcaaatcga aattactcaa gcttcctatg gctagagtcg cgagaagttg ttgggcagta
     3061 gacataggtt atattgttct tagctacacg atcattagaa aggaaatcct attatgtata
     3121 gttatcaaga agatgcaaaa gtccaaaaaa atcgctggtg gattttgatt gctatatcta
     3181 tgtttacctt catgtccaca ttggatggca gtattgtcaa tattgcacta cctaccatct
     3241 cagatgatat gggcatacca atgaatcaag cggaatgggt agtgtccgtt tatctgatga
     3301 ttgtctgttc ttgtttgttg ctgtttggta aaattggcga tagccgtggg aaaatcaaag
     3361 tatttcggat tggtacgctg atctttgtct tgggatcgct gttgtgtggg ttcaatcatt
     3421 cgctaggtat tttattgttc gcacgggtgg tacaagccat tggtgctagt atgactatgg
     3481 ctacaaatgc cggaatcatc acggaagtct ttcccataca tgaacgtggt cgggcattgg
     3541 gagcaatagg tgcgtttgtt tcattaggct cgattgctgg accaggtctt ggcggcttga
     3601 ttttgtccca attttcttgg gcgtacattt tttggatcaa tgtaccggtg ggaatcgtaa
     3661 cgatgttgat tgctgaaaaa ttcttaccaa aagatatcac catgagcggc catacaatcg
     3721 atggaggggg ctttgctgcc attgcggcta cgattatcag cttttttgga gcaatctttt
     3781 tggggcaaga aagtggcttt ttccatccag tcccccttgt actgttcgta atttcagtga
     3841 ttgcctttgt cagcttttta aaagttgaaa agaaagcagc ctctccattg atttctttcg
     3901 gtatttttaa gaacaagatt tttaccatga gcttgattac agccttgttg attttttctt
     3961 ccaacttctt tgtcaatgta gtgattcctt tttatctgca aaatgctcgc gggttgagtc
     4021 ctagctatgc tgggctgttg atgatggtct ttcctttgat gatggtcgtc ggggcgcctt
     4081 taagcggcta cctgaccgac cgggttggcc cggagatttt ggtattagta ggcttgggct
     4141 tattgtcggt aacccaggtc atgtatatgt ttttgtcagt ggactctcct ttgtggctat
     4201 acattgtcgc tactgccatc atgggtgccg gcaatgcctt gttccagtcc cccaataata
     4261 cgatggttat gagctcggtc actatcgaaa acttgggact ggcaggctcg atgaattcct
     4321 ttgcccgaaa tttggggatg gtcagcggga tttcgctttc tacgacggtc ttatatcaag
     4381 cgatgtctgc taagatgggc cagcaagtaa ctaactatat cgcaaatcgg ccggatgtct
     4441 ttttatatgg aatgaagatt acctttttag gcagctttgt tttgtgtttt gttgcctttt
     4501 tcctgactat ctggcgtatc aaaaaacaag gaggtattca gaaaaatgtc tgaaaaaacc
     4561 actgttgaag aatttttgga ggcctgcgta tgggtgagtg ggatttccat ggatgatgga
     4621 agatgaagtg aacttctaaa agccgaaaaa ctcaagtatt atcttcaaaa tactagtgct
     4681 caatgagatg cttgatttga tcacaagaag actgcgaaag ccgctggcaa ccgcaagcta
     4741 ggtatcccac cgatggacta cgttttagag gctactggtt atgaatacgg agccaacgct
     4801 ctcatctgca taagaataca tcacccagat tatgtaaaga ttttcgatac ttctgtcaaa
     4861 aaatcattaa gatagataaa tgatttccgt ctagtcaaat tggttcagaa tgtagacaca
     4921 cagatggtaa gaagtcactc acaattcgag aatggacttg tcctatttgc cgtatacatc
     4981 ataatcgaaa cgtcaacgat agtatcaata ttttgaccaa gggctatgaa tacaagcatt
     5041 gccttagaaa acatcaagaa ccttaggaac aacggggata gcttggttaa taagagatac
     5101 cgctgtttag gcttgcaagt atactctttt atcaagaatt ccgtggcttt agtcatgaga
     5161 ggcttaatac tatgaaaatt ttctttagca tttttgattt aggttccttt tctaattata
     5221 ataagatgac cactacagta acctactgaa atatataaac agccactgta gtaccatttt
     5281 caaagtagtc tatgagagga gaatcttcat tcttatgaac gctggaattg cggatatgaa
     5341 tttaataaaa aaaaccctta atgattttac ttccaattca atatcaaaag gtactggtat
     5401 caatttaagc acaataaaaa agctgaaaag tggtgaaaga tcagtggaaa agctgaatct
     5461 tttagatgct ataaaaataa cggaatttgc tatgaaaaat ggaaaagctg agattgaaat
     5521 atggagataa ttatcgtcta gtgaattact tgccacttag ctgaatttaa cgatccttgg
     5581 tgcttgaagg gggagattct tgggaataga gcatacttgc aagcctatgt ctttactaac
     5641 aacgatatct cttattaacc aagctatccc cgtagttcta aggcttttac ttttatctaa
     5701 gcaataatcg tattcaaagg aaatttttga cccttagaaa gtctcatttt atcagacgtg
     5761 agcttaggca ttgctgaatt ttgttaattc ggttttaggt tgtgctttga gcataatatg
     5821 aaagtattct ttatcacgat ttcattcatc taaggtaatg tgatgtgatt ctgaaattct
     5881 ttcaaaggca gtttttgcat aagctgacat tacatcatca atgacatgtt tacaatgttt
     5941 cactactaaa ataagggggt aaccaagaag aaaaactgaa tgattatttg tatctaattc
     6001 catggtatat caaccatttc ctatatagac tgattatgac atggattaaa ataaaaaggc
     6061 actatgtctt aattgtcggt tttcgagtta ccgaatggca ttcatcaccc acctatagag
     6121 gatgggcgac ttctgcctga aataagttac actacttata acttctaata aaattagatt
     6181 gagtcattat tatttaacat caacgatttt ccagtttcca tttttttgta atactaattt
     6241 gtactgaaag tagctagtgg tttttgatac attatcaagg tattttatct ttgtactcac
     6301 tagaaaattt tttccgtttt gtagataaac tggattctct aactccgaaa actttaagtc
     6361 aatattgatt ggtcgcatcg caccattttc aacataatac tccaattctt tttcagaagc
     6421 tgatggataa agtttaaaaa atgtttctaa aaaatcggtg atttcttccg ttgttttggc
     6481 atcaatttct gaatcgtttt ctacttgttt tgcttcatat tttgccttgt ctggctttcc
     6541 aatcattgtt ggcaaactag ttactaaatg attcctgttt tcatcttcaa agattgtcac
     6601 tcgatatgca gaagaaattg attgcgtctt ttttccctct gtaatatgtt gctccactaa
     6661 aaatgaaacg acaaattctt ccgagtgttt ttcaacatct agaattttta cagattgaac
     6721 ttcggaactc gtgggaatat ctgctcgaac catatcttgg attaaagcga gaccgttttc
     6781 tgtaaggtac tgttcgagat tactcattct cttttcaatt gcttctttgt tatttttcca
     6841 tgaaaaatat tctttcgcaa aatcctctgt aaaactttca acgccagaag tattcactac
     6901 cttctctttt ataaccactt tttcatgagt tgtatgttga tcaatggcgg tgaaattttt
     6961 ataaacgcca aaagcaagac tacaagacaa taaaagccaa agggcaagca ccatttttcg
     7021 atgcttaccc acggatacaa ctcgttcttt tttctttttt gggctctttt ccttttgatt
     7081 ccgttcaatt tttatcttca ttctttttcc tcttttctct tatttgtatc ggccagctcc
     7141 gataagatgc tgccgccaat agttttccgt tagattcgtc caccccactg gatctcctgc
     7201 atgaaacatg cgattctccc ctgcgtaaat gcccacatgg gtcacataag taccggcatc
     7261 ataggttgaa tgaaagaaaa ctaaatcacc tggtttggca tcttttagat caatatgagt
     7321 catggcatca tattgatcct gagccacccg aggaagtttc aggtcaactt tggcataaca
     7381 ccattgggtc aagccactac aatcaaaccc cgtttctgga cttgagccac caaacacata
     7441 ggccgttcct tcatacttaa atgcctcatc aaaaatttct tggactattt tgtcatcaaa
     7501 ctgagttgta gttaggtatt gcttcactaa taaacagtaa aacatattgc cataattata
     7561 ccgccaccca ccattttcct taatcgcgat tgggttgggg taatcgactt tttgaccacc
     7621 tgatttttcc tttgaaaaag attcagctaa agcaaaacta tgcttcttcc cgtttttccc
     7681 gacatgatct agatacccgc caccatagtt ataggcctga ataatactat cttgatcaca
     7741 ccctagttct ttggaacgct taaccaaaga cgcaaaatag agacagcctt gtttgatgga
     7801 tgcctcggta cttaatgaat taggtggtaa tccggctgac tcagaacttt gcataacgtc
     7861 ttccattgtg ccaccagatt ccacttgaat aatcgccaaa agaattggaa tatactctgt
     7921 tatatccgat tctttggcat acttttccac cattgcacgg tgtttcaata cttcttctga
     7981 gacactagtt ccgccaggag aagtgccaga actaccattt ccctcactgt cttcaccaaa
     8041 caacaaaccc acacacatca aaatacccat aaaagagatg gtcagaaaag ttaatgaaat
     8101 aacacccact ttcttcaagt tcattttttc tcacctgacc ttgattttgg acgatggttc
     8161 attctttttt gtactttttg attggtctgc tttggcagag tggacctctg tttcacttgt
     8221 tggaaagaat ttttcttact tgctgattgg cttttccctt ttgaaatgat ttcttgacta
     8281 gttagttttc gtttgatttc gggattcaga tttgctctca caatccgctt tggtgcttct
     8341 tttttcagca tcatatcttt ctgaggttga gctgctttat ctattggaat attcgccctt
     8401 ctttttccct gacgatttgt tgcttcactc agtatcttgc gtttttcgtc cattttcgca
     8461 tttcttcgtt gtcgttgttt ttctcgcaaa tccactcgat ccgctttttc ttggaacagt
     8521 ccgcgcttga attcttctgg tgcttttttc gacttttcga ttcctttatg gagattgtat
     8581 ttcaaattcg ttggcgtatt ccttacctga tcctttactt gtttagtctt atctttcacc
     8641 aaagcttggg tatccaaaac tttgccgatt tttctcccag ccaaattcat tcgggattgt
     8701 ttcttattat ttgaaactgg attctcctta gttaagtcag atagtatttc gtgatcgttc
     8761 ggtaatcgtg aattctttcg tagagaagaa ccggatggct taaatttgga ttttgattgt
     8821 tcctttgcca acttatttcc gactgctgca ccaccaccaa aagccaaagc tcgtcccaca
     8881 tttcgattga gttgccgcaa ttttcgattc attaacattt gcggttttcg catgacgcgt
     8941 cttcccattg actggctatc attactctgg aggttgaaca tactcataat gtcgcccaat
     9001 ttgaaataga taccggcaaa ggtcacaatt tgcagaaaag caaccatgaa aaatggatag
     9061 gttgccgaaa tattgaaaaa catcgtggag atgctaaatg cagtcgtaat caccaaagta
     9121 acacccgctc gcatcataat cgtattgaat aaacgaataa tcgccttctt tcctaaactt
     9181 tcataagtcg gcaacatgga caataagaaa ctaattggca gaaacatcgc aaagataatg
     9241 aagagaattt gcgagaacaa cataatccct gttagaagaa aaacaaagaa ggaaatgcca
     9301 atattgaaca ataccaaaaa gaccacggtc cctaaacggt tcatggtctt ggtaatactg
     9361 agattcgcat tgtcattgtc ttcaatctct gccttgaccg cttcttcccg atctttgcct
     9421 ttgttttcat ctggactcac agatagaatc ttgttgaccc ggtcttcacc aatttcttct
     9481 atgttggaat catcaaattg cagtagtaac caaggttgtt ggacttgaat cgaaaacaaa
     9541 ctatcccgaa tcaaatccac actatctttt ccttggcttt ctgaattggg tacaacgatc
     9601 tcggttccaa gggtaagggc cgcttcacta acatctgagc taaagtcatt gatttttgtg
     9661 atataggtag gcgcataagc aatgaacgaa cccgatagta gaaaaatcat cacaaaatta
     9721 atcacggctc gaactgcttt cgtggtttct cgttttaata atccggtata cgccacatac
     9781 acccccagag ctaaaatcat caataataga aacccaaaat aaaatccgga ggtctggagt
     9841 ccattttcag taataccagc caatgtttgg atattctttc caatactttc agccgtatcc
     9901 gaaatgaaat ctaatttgta agcctcttga accacataac ccgtggcgtt cgacaaatac
     9961 aaactcaccg tccaaatgaa attagtaatg gcataaagac catacatcac gcttttccct
    10021 aagccatcac cccaattcca aggcaaccaa tcccaagagc tatccacaaa gaaatctagt
    10081 tgatagttgt tcagtgaata tttggaatat agatttcctg cttcaactgt atcatcaact
    10141 agccctgtcg cctcggctac cgtaccaact aaactcaata gaactatcag agtgagtatg
    10201 ctaataaaaa cgattcccac aatccgaaaa agtttctttt tcatcccctc actccattct
    10261 ctcttgaaca ggtggacggg tatcaaaggc atggaagagt tcttcaaaga ctggatgtac
    10321 ctgaaccacg cctacccgac catacaaatc ctgcatcaag cattggccat tttccaaatc
    10381 tcgtaggcgt ttttgattgc tttcatcttc tcgatccaag ccaaagaatt ccaaggtttt
    10441 cttgatttca tgaatatcgg tactgcgaaa cgcaaacttc aacccgatat tattcttcaa
    10501 gcgttcatcc agtaaatcat cactattttg cgtgacaaag taaaccccgg cattcatagc
    10561 ccgcccagca cgaacgagct tattcgataa tgttttccct tgcgctactt gaagaaaact
    10621 ccacgcctca tctaagtcta caattttgaa gatttctcga ttactatgga taaagtccaa
    10681 ggcaaaagtg gaaatgacga ttagcatgga aacactaagc aattccatgg tggtatattc
    10741 ttcaaaagtg gtttctgcat ctggtaaaac caaatccgct acttgaatga tatttaactg
    10801 cctatctaaa ctaatcgact gggtaatcga accatctgag aaaagcaaat gggcaaaatc
    10861 ataatcggta aaggactcga tgtgatccgc gatattttcc gcaactggtg agccttcttt
    10921 tcgaagctca ttaattactt gtaataatcc ccgttgattg ctttgggtaa ccgtccgaat
    10981 ggccttacgc aacactggaa acttctcccc atctcgacta gaaattcctg ttaaaaaggt
    11041 cagaatatca attgctagac tttcagaatc cttctttttc tccataatca cataaggatc
    11101 aagtaatcct tgattttttg gcttactagt taagttgaga atattgattt catccgcaat
    11161 ttctggcaag gtttctttcc agccaccccg ttcccctttt ggatcgacaa tcacagcttg
    11221 tccaccaaaa aggacggcgt aataaactaa gagattgtta ctaaaggact ttccgccacc
    11281 gagtgaaccg aggaatgccg ctgctagcgc attggtaact gaatccttga ccccttgtga
    11341 ggccaatgcc ggtttcaggt aaacattgcg ccccgtatct acgttataac caaagtaaat
    11401 gccttccaac tcccctaaca tctgagtggc gccaaaacca agtccggcga gaaaatcaga
    11461 cgtaacatac tggatataat cattcatgta tcgcttacta gaaggtaaga attcttcatg
    11521 tagccccatc atatcgccaa aaggccggac tagttttaca ttggtatcat cataaaaatc
    11581 tagcacttca tcacaccggc gctttagttc atctactgat tcggcactta ctcgaaccac
    11641 atagctcagt ttgtacatgg attctttgga ctgatccaag gtagtttcca attcatctac
    11701 ggaatccaat gcatctaaga cattggaatt tgtttcattg tcagattgat aggcatggtt
    11761 gtccaagtct tttaattcct ttttcttatt gcgaacggta gcaagtgcct ttttgttcgt
    11821 cacaatctcc acattcatac tagtgtcaat tgggaatgta aattgttgtt gctggtaata
    11881 gaaaagttct gaggagggaa actccatttc ccccacaatt gtattaattg ttaagtacgc
    11941 tacatatgat tcatgattct catgttccat gcataagtac cggggctttt cttcaatcaa
    12001 acaacgactg ggacgtaata agtcgtaacg tttcaccaaa gtttccgact tcagcttttt
    12061 ctttggtagc tgaaattcat attcttcaaa tggtgtaccc ttttcgccat agatatgttc
    12121 aatcaaatac atcagatcac tcggtgtgac tcgtctgact ttaaatcttc gagccaattt
    12181 actttccatt agtttttcaa gcttggtata tcggcgaatt tcttcattgg ataaggaaac
    12241 aaaatcgccc atcaaatgat gattcactcc atagacaaat tcttgaaagc cggagaagaa
    12301 agatttcttg agattcttta gattgacctc ttcatctgtc gcaatcagtt tgaagccaat
    12361 aaaaaagcga taatcaatct gactatcgcc aatcatggat actaatgcct ctgtctgtaa
    12421 atcaattcgt tgtttcgcta cttctgttaa tcgcccggta atttcctttt ttgatcgttc
    12481 ttgcgtggca cgaatactac tttctgtggc aatttgtaag gcatgaatct tgccttcacg
    12541 attttgcgca atcaattgac gaaagttatc gtggacttga tatttctgtt caggtgacaa
    12601 aaaggagtaa ttgtaaggta ttaactcata gtaggcaaaa cattctccct cttgattaaa
    12661 gacaagatta ttttcaatat acttaatcgg gtacatagtt cacactcctt accagagtaa
    12721 tgggttcgtc ccatcgtttc ttctgttctt tgactttctt tcctgcgaaa gtgaccttaa
    12781 atcgtaagtg atagctaata aaagatcgta aaaatcccaa tggtttctta ccgtcaaacg
    12841 ttttttgcga catgaaccaa gtaactgcca ccggtatacc taagtatttt aaaaaggccc
    12901 cctctatcat agatagtgga ggcacatggg caaatacgat gacaaacagc aaggataaaa
    12961 caaaccaagc catctggtta aaagtcacag gaaaaggcag ttgaaagtca ttaattgcat
    13021 aaatgacctt ttcaactgcc caaatactgg tgtagctttt tattttcttc atcaaatcat
    13081 tcctttaaaa agaaggatag tttagaaatc aactaccctt caataatttt gttaatatgg
    13141 atactcaaaa acacctcgac tcgttaccaa ataattgcc
//
LOCUS       DADVXK010000077        12820 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.078, whole genome shotgun sequence.
ACCESSION   DADVXK010000077 DADVXK010000000
VERSION     DADVXK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.078"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            58..3585
                     /locus_tag="KB909_002077"
     CDS             58..3585
                     /locus_tag="KB909_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBB6838084.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3582..7304
                     /gene="addA"
                     /locus_tag="KB909_002078"
     CDS             3582..7304
                     /gene="addA"
                     /locus_tag="KB909_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBB6838085.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7373..7714
                     /locus_tag="KB909_002079"
     CDS             7373..7714
                     /locus_tag="KB909_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838086.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8023..9066
                     /gene="pheS"
                     /locus_tag="KB909_002080"
     CDS             8023..9066
                     /gene="pheS"
                     /locus_tag="KB909_002080"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBB6838087.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9071..11491
                     /locus_tag="KB909_002081"
     CDS             9071..11491
                     /locus_tag="KB909_002081"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBB6838088.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11661..12671)
                     /gene="trpS"
                     /locus_tag="KB909_002082"
     CDS             complement(11661..12671)
                     /gene="trpS"
                     /locus_tag="KB909_002082"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBB6838089.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4343 a         2234 c         2726 g         3517 t
ORIGIN      
        1 tcagtatttt ttgatataat aaaggagcac cgtatcatgt gttgaaggag gaaaagcatg
       61 tctttacaat ttattcttgg aaacgggaaa aaagatcacc gtcaagtctt gatcgacgaa
      121 gcatccgctt ggctcgacca ggatgcaagt aaccaagtat ttttccttgt tcccaactac
      181 agcaaattcg aacaggaaca agaaatttta gcggagatgc gaagaagaag cggaaaaaaa
      241 actttcagca caacaaacgt tcaagtattt agtttttatc gtctggcttg gtatttgctg
      301 caacagacaa ctcttcttac aggaaatgaa ttatcagaat caggatctgc aatgatcttg
      361 cgacagattt tagaaaaaaa tgaggaagaa ttaacaatct ttcgcggaga aatcaataaa
      421 agagggttta ttcgtcaatt acaagaactc tacagtgaat tgcgtacagg aaatattcaa
      481 ccagaagacc tgatgctttt atttggtgat tcacctaatg cagaagacca gcaacttaaa
      541 atgaaagact tgaagctgat tttttcagct tatgacagcg aattgactca acgtgcacta
      601 acaaatgaag atgcactatc tatactagca aattatatgc agacacaaga tttcaacaac
      661 gtcaaattta ttgtcagtgg tttttctcga atcaatggtc aagagtatca attactgcag
      721 gcaatgatgg aaaaggggca attggttgtc gatttattgc tggatcgtcc ttatacagcg
      781 gatcttccag aagtacttac gctctttcat gagactggaa agctttattt ccgtcttttt
      841 caaagtgcaa gagaacggaa agtccctata ttagtggacc gatttgcacc agagcagact
      901 cgtccgacag agcttcaact gctgcaaaca atgtgggaag agacatctag ccaaaagaaa
      961 gcggcagtac acaaaatagg gggacaagag catctccatt tgtgggaagc tgaaaatcca
     1021 actgaagaag tccgacaatt agctgttgaa atcagacgac tagtcagtga agaaaactac
     1081 cgttatcgtg atatccaagt gctgacaaaa aatatgtctt tatatggaaa tatccttcgg
     1141 ccgatctttc aagaaatggc aattcctttt tatatcgatg aagaacaaat gatggaaaat
     1201 catccgctga tcgaatggat caacagtctg ttcgctcttg accgctattc ttatcggcta
     1261 agtgatatta tgcgtttttt caaaactgaa ttatttctgt cgacggaagc agaaaccgaa
     1321 cttgatgaat ggaaacaaga gcgagatgaa ttcaggaaaa aactggacat cactgaaaat
     1381 gtagcacttg cttacaatta tcaaggaact tattggactc gtgaaaaaga ctggcagttt
     1441 gtggcgtatg attttgaagc agaacagatt gaagacgtac agtatttgga agaacagtca
     1501 aatacgatta gacgattatt tcagaaagct gtaccagtat ttttgaaaaa aataaagaaa
     1561 agcaaaacag gacaagaggc cgcaaatgtt ttttatcaat ttttgatcca aagtggcgta
     1621 cagcaacaat tattgttttg gcgtaatcag gaagtagaca gaggaaactt agaagcggca
     1681 agaaaccatg agcagacatg gggagcgctg attgatctgt tggatgaata tgtagtaatt
     1741 tatggtgaat cggcttttga ctggtcactg ttccaagaaa tcattacaag tggtctagaa
     1801 aatctaagtt atggtaaaat ccctaccgca atcgaccaag tgcgaatcaa tcgtttggaa
     1861 ttagttcgac caaatcaagc tgccgtcact tttgcattag ggttgaatga tcaagtgttt
     1921 ccagaccgaa aagagacaaa aggattgttg tccagtgaag aacgagaagt attaaatcag
     1981 gccttgccag atggacagtt tttattcgac ccatcaaagg aaagtatctc ttttgagcct
     2041 ttccaagcct atcttgtttt tctttccgga acagatcgat tatatcttag ttatgcacaa
     2101 agctatgaca cagatggttc gctgaagatg tctccttatt tgcgtagaat cacagaatat
     2161 ttatctgttc ccgtcgagag aaaagagcat ttgacgatcg aaagcgaccc taattgttat
     2221 gtagggactt acagaagcgg aatcaataca gtcaatagga tttatcgatt agctttagat
     2281 gaaaaaaaac ctgtaccaaa gcactggcaa aagctcaaag aattagtact gaattcgtca
     2341 tggcgaaatt ttgctttaca gatttttgaa agtcaggaac atttaaatgt tcctgtttcg
     2401 atgccagaaa aaatggcgga agagctttat ggaaaagaga tttatacttc aatttcacgt
     2461 atggagaatt tttataattg tgaatacaaa tacttcatgc aatttggttt gaaattgaaa
     2521 gaacgaactg tttatggtct aactccagca gcaactggtg atttttatca tgaatcattg
     2581 gatcgtttct tcaagctact gttttcaaac caattatcct tagtgaatat gtccgatgcg
     2641 cagcgtagag actttactga aaaagtgctg caggaagtat tcggagaact tcggtttgag
     2701 atattggata gttctgcaag aatgaactat atccgctacc agttaggaca gacgattcaa
     2761 aaagtgacat gggctttgca aaaacagagc aaaaatacag gcatgcatcc tcttcagaca
     2821 gagattctat ttggtcagat tgctggagca aaaggtatca caggtctgga attaccgttg
     2881 agtaatggtg gaaaactcca tgttcgaggg aaaatcgatc gaatcgatgt agcttctgaa
     2941 caagaagata cttggctaag cgtcgttgat tacaaatcta gcggacgttc attcgatgtc
     3001 acagaagctt attatggcat ggctatgcaa ttattgacgt atctggacgt agcattgatg
     3061 gatgcggtac gtttgactgg aaaggcggct gttaaaccag caggatcata ttatttacat
     3121 gttcataatc ctgtattgac ggagacagat gatgtagaga agaatacatt gaaaaaattt
     3181 agttatgatg gcgtttttgt cgatgatccc gctcttttag aagtactaga tcattcactg
     3241 gaagcaaaag aacaatcact gatctatcca gtgaaaaaaa atgcgaaaga tgaataccaa
     3301 aaaggtagtt tcagtaaaga caaatttttc acggaagaag aactgcaact attcatggcg
     3361 cataatcggg aaaatatgcg gttagctgga gatgcgatta cttccggaga aatcaaacta
     3421 aatccagctt ataaagataa acagcggatt gcctgcgaat tttgtccatt cagaagcatc
     3481 tgtacgtttg atgtgatgct gaaagaaaat aattaccacc gtctggagaa aatagataag
     3541 gaagaagcac tgcgtagaat attgaaaagg agtgaagaag agtgaatcaa attcctttaa
     3601 aaccgcaaaa tgaacgattc acagatgatc agtggcaagc gatttttgat caaggagata
     3661 atctattagt ctctgcgtct gccggatcag gtaaaactac agtgcttgtt cgaagagtga
     3721 ttgaaaaact aaaaatgggt tttgatatcg atgaattatt gattgtgaca tttactgaag
     3781 ctgccgcaag agaaatgaaa gaaagaattc aagaggcatt acaagaatcc gtcaatagcg
     3841 aaagtgaccc tgtacgtaga cagcatttta ctaagcagtt agttttattg cccacagcga
     3901 atatctcaac cttacatgct ttttgcctga cagttattcg acgttattat tacttaattg
     3961 atattgatcc agtctttcgc atgttaacag atgaaacaga aacgatcttg atgaaggagg
     4021 atgtgtggga cgagctgaga gaagcacttt atgcagaaaa tgatgaacga tttttccaat
     4081 taacaatgaa tttttctaat gatcgttcag atgacggctt gacgaatctg gtgttttctc
     4141 tttatgagtt tgcccgtgcc aaccctgacc cccaaaaatg gctagaacag ttaagcgata
     4201 attatcgttt gcctgagggg ctagcgaaat ctcgattata tcaaaaacaa atccgtcctt
     4261 tagttttggc agatatatac caatgtgtac agttatatga acagatgact cagttagcac
     4321 aaggtgaagg attagaaaaa atgcatgagc aagtagctgg agaacaacag cagatcaaga
     4381 atatctatga agcgttctcg caagatcggt tagaagaagc ttatgctggt ttggaacaac
     4441 taactttttc aacttttaag agcagtcgga aagcagaatt gaaagaaatt tccaatgaag
     4501 tcaagggcat gagggataaa gcaaaaaaac tgattcagca gataagtaaa agttattttc
     4561 ctgtttcccc aagccaaatg gaagaattaa cggacaaagc actaccgtta gtcgaagaaa
     4621 tgacaaaagt cacgcaaagc ttcatggacg gtttcagtat gcgtaaacgg gaaaaaggtg
     4681 tgctggattt caatgatctg gaacatttag cgttgcagat tctcacagaa aaaacgaaag
     4741 atgtatggct gccaagtgaa gcttcaaaac attatcgaaa aaaattcaaa gaagtaatgg
     4801 tagatgaata tcaagacgtg aaccaattac aagaagccat tttatactgg ctaagagaac
     4861 ccgatgatac aaaaggaaat atgttcatgg ttggggatgt caaacaatcc atctattctt
     4921 tccgtttagc agatcctagt ttatttatcg ggaaatacga gaatttctca aagaaagaag
     4981 gcggacgtcg aatcgttttg gctgagaact tccgctctag aaaagaagtc ctttctttta
     5041 cgaatcttat ttttgaacaa ctaatggatc cagcagtggg tcaaatcaat tatgacgaag
     5101 cagccaaact gatccaagga ttttcagact ttccagagaa tgaacagttt gagccggaaa
     5161 tcatgatcta tgaaaaagaa caggaagaat cagagattga gattccgacg gatgatatac
     5221 tggaagacaa aacagaaggc gaacttttta tgacaggact aaaaattcgt caattaattg
     5281 attcctcctt tatgatttat gataaaaaat caaaaaaaag tcgtccgata gagtacaaag
     5341 acattgttct cttgacacct acaaagaaga acaacttaac gattttagag attttcaaaa
     5401 cattggatat tccattagag atgaatgatg ctcaaaacta ttttcaagcg acagaaattc
     5461 gcacgatgat ctcgctgcta caattaatcg ataatcccta tcaagatatt ccgcttgcgg
     5521 ctgtattgcg ctcaccgatc gtgggtctga ttgaaccaga attagccagc attcgattag
     5581 ctaaccgtgc acatacttac tatgatgctg tgcttgctta tcaagcatca aacgaagatg
     5641 aattagcagc taagctggaa cattttggca agcaactaga gcattggcga gaacttgctc
     5701 gccgttcttc gatcactgac ttgttatggg atatctatta tgagacggga tatctagagt
     5761 atgtggtcgg tctgccagca ggggcacaga gacaagccaa tctttatgca ttggttgatc
     5821 gtgccaaagc ttacgagcaa agttctttca gaggattata ccagttcgtg cgtttcattg
     5881 aaaaaatgca agaaaaagat aaagacttag cagaaccagt catttcaata gaagataatg
     5941 ctgttcgcgt tatgacgatc catgcaagta aaggcttgga attcccagtt gtatttttgt
     6001 tagatatgac aaaggagttc aacttacaag acttgcgcaa tcggtatgct tttgaagaaa
     6061 aacttggagc aggaattcgc tatatggatc ctgaaacacg agtgttatat gatacgttac
     6121 cgtttcaagc catcaaattg gcaaagcaaa acaaattgtt gtcggaagaa atgcgtaaat
     6181 tgtatgtagg attgactcgg gcagaacaaa agcttttcat tgtcggttcc tataaaaata
     6241 aagagcaaat gatccaaacg tggtctgaag cagctgatca tgaggagtta gtttttgatc
     6301 ctgcgctacg tttgaagggc agaagcagct tgatgaattg gattggttac ggattgatcc
     6361 gtcatcctga aatgcagaaa tacttagagg aagaaatttc gacttctctt cttcaacatt
     6421 caaatgcaca gttttctatt tcatggatga atcagcaatc gatcattgaa caaagacagt
     6481 tgcttgctga aaaagaactg gttaacttag atcagcagat gaaagaagat gaaactttat
     6541 tagcagattc gttacaaaaa cgtctggcat atgaatatcc ttatcaagct tcttcacaaa
     6601 ccacaagtta tcaatctgta tctgaaatca aacgattatt cgaagatcca gatgatacac
     6661 aagaatcacg tttgactctg gaaagcagtc agaacaaagc agcatcccgt caatttcgtt
     6721 atacgcaaga acaactagca gaaccaaaat ttttgcaaaa agatcggcaa gtgtcagcag
     6781 ctgctgttgg aactgctacg catgctttgt tacaattact gccattagag atgccaacta
     6841 cagagagtat ccatcaaaaa ttacaggaat tggtaaggaa acggttagta gacgaaaaag
     6901 tcgcgaaaaa agtagatgtt tcttctatta tatggttctt tcaaacagaa cttggtcaac
     6961 agctgattgc caacaaagaa aacgtaaaac gagaacaacc tttttccatg ctgcttcctg
     7021 ctgacgaagt atttcaagac tatccaaatc aagaagatga actattaatc cacggaatcg
     7081 tcgatggata cctagaagaa aaagatcatc tcaatatcta tgattttaaa acagatttta
     7141 ttttacatcc ggatgatcca gcagaaatag atgcaatcgt ccaaaaatat caaggacagc
     7201 taagacttta ccaacaagca atgtcagaag ctttgaataa gccagtagaa aatgttttcc
     7261 taattttgct tcgagtgaaa caaattataa acattaacaa ataattataa ttgagcaaac
     7321 ttgacttatg ttttgtaagg attatgctat actctgggaa gaggtgagta tgatggagct
     7381 aacacagaca gaattcgttt tatgccctaa atttgaaaaa acattctcta ttttaggaaa
     7441 aaaatggaac ggattgatta tcgatgtact actcgaaaac ggtccgcaac gctttgttga
     7501 gcttgcggca aaaatcccga tggtcagtga tcgagtatta gtcgaacgct tgaaggaatt
     7561 agaaaaagaa ggaatagtca ctcgaaactt tgcctgtagc gaaaagagcc gttcagaata
     7621 tctcttgact gaaaaaggag cagacttgca aaaagcgatg cgtcaaatac aagtttggag
     7681 cgaaaaatgg atcacagagg aagaatgcgg ttgattttgt aaaaaaaatc ttgtaaacta
     7741 tagtccatac gaataagtaa agaacgatga cgaaaaagag tagtttggct aaaccagttc
     7801 agggagatct gtcgcagact gaaagcagat cctgtgtttg aaaaatgaag ttcactttcc
     7861 gagttcgtct gataaaatca gaccggcaat tgtcgttaac gaagtaagag tgcggtgtaa
     7921 gtcatttatc cgcaaattag gatggtaacg cgaagacctc gttccttaac aggaatgagg
     7981 tctttttgtt ttgtatttgg aatttaaagg aggaacaagc acatgtctct acaagcacaa
     8041 ttagagagct tgaaagaagc aacgctcgtc aaaatcacag cggcacaaga tttaaatgaa
     8101 ttaaatcaaa tacgtgttga aacgttagga aaaaaaggac cgatcacaga agtattacgt
     8161 gggatgaaag atctaagtcc agaagagcga ccaaaagtcg gaagtttcgc aaatgagatc
     8221 cgagatcttt tgacagaaga gatcgagcga aaaaaacaag tattagaaga agaagcgtta
     8281 aatgcagctt tggcaaaaga aacaatagac gtgacactac ctggtagaaa agtaaaacat
     8341 ggtacacgtc atatcgtgac acaaatcatg gaagaaattg aagatatttt tgtgggtatg
     8401 ggctatcaga tcgtagaagg atatgaagta gaatctgatc attacaattt cgaacggatg
     8461 aatctgccaa aagatcatcc agcaagggac atgcaagata ctttctatat ttcagacgag
     8521 atattgattc ggacacatac ttcaccagtc caagcacgga caatggaaaa acatgatttc
     8581 tctaagggtg ctctacgaat gatctcgcca gggaaagtct tccgcagaga tacagatgat
     8641 gcgacccaca gtcatcagtt ccatcaaatt gaagggctag ttgttgataa aaacatcaca
     8701 atgggcgacc ttaaaggaac attagaagtc gtaatgaaaa aaatgtttgg ggaagatcgt
     8761 gaaattcgtt tgcgtccaag ttatttccca tttacggaac catcagtaga agtagatgtc
     8821 agctgtttca aatgtggtgg tgccggttgt aacgtatgta aatacactgg atggatcgaa
     8881 attttaggag ctggcatggt acacccgaat gtgttgaaga tgtcaggaat cgatccagaa
     8941 gaatattcag gctttgcttt cggccttgga ccagaccgcg tagctatgtt gcggtatgga
     9001 gtgaatgata tccgtaattt ctatcaaaat gacttacgtt tcttaagtca gttcaagggg
     9061 gagtaagaaa atgttagttt catataaatg gctcaatcgt tatgtagatt tatcgaatgt
     9121 aacaccaaaa gaattagcgg ataagatgtc tgtgacagga atcgaagtag agggagtaac
     9181 ggttccagaa gaaggcttga aaaaaatcgt tgtcggtgaa gtcaaggaat gcgtaccaca
     9241 tccagattct gatcaccttt ctatttgtca agtcgatatt ggcgaagacg aactgtctca
     9301 aatcgtttgt ggagcgccta atgtgaaggt tggaatcaaa gtgattgttg cacttcctaa
     9361 ctcacgtatc gctggtaatg taaaaatcaa aaaaggaaaa atgcgtggcc aagtatcaaa
     9421 tggcatgatt tgctcattac aagaaattgg ctattcagat agtgttatac cgaaagaata
     9481 cgctgaaggt atctattata tgccacaaga agctgtaaat ggcgatccag tttttcctta
     9541 tttggatatg gatgattcga ttattgaatt atctatcaca ccgaatcgtg cggatgcatt
     9601 gtcaatgcgt ggcgtagctt atgaagttgg ggcaatttat cgtcagactc ctacattcga
     9661 tgacgaaaag ctggtagaat cctcacgtcc tgctagcgat aaaattcaag tggaagttga
     9721 agataaagaa gcagttcctg cttatcaaat cagaatcatt gaaggagtaa gaatccagcc
     9781 aagtcctcaa tggctgcaaa atcttttgat gaacgaaggc attcgtccaa tcaacaatgt
     9841 agtagatgtg acgaactata ttttgctttt attcggacaa ccactacatg catttgacta
     9901 cgacaaattg aaatcaaaag agatctttgt ccgccgtgca aaagaaaatg aaacattagt
     9961 aacactagat ggagaatctc gggaattgac aactgacaat ctcgtcatta ctaacggcaa
    10021 agaaccagtt gctttagctg gtgtcatggg agggttagac tcagagatca cgaatgaaac
    10081 aacaacagtt gcactagaat ctgctttatt tgatccaatt tcgattcgtc gtacagcaaa
    10141 acaatttaat ttgcgtagtg aatcctctgc acgttttgaa aaaggaatca accatgcgac
    10201 tgttggagaa gccagtgagg ttgctgcagc aatgatcgtt tctcttgcgg gtggggaagt
    10261 tctacaaggc gcggtcaaag gctcagagat caaagcagaa gacgtatcag tgaagatttc
    10321 acttgaacgc atcaatcaat atttaggaac atctcttgtc gttaaagaag taaatgagat
    10381 ttttgaagca cttggattta gctatgaaga aaaggagtat gtttattccg tagtagtacc
    10441 accaagacgc tgggatatcc aaatcgaagc agatattatc gaagaagttg ctcgtattta
    10501 tggatacgac cagttgccat ctacacttcc aagtggagaa acggttgctg gaagcttgtc
    10561 aaaagaacaa gaaactactc gtaaaattcg tacaatcttt gaaggaagcg gattgagcga
    10621 agcaatcagt tatgcattga caacagaaga aaaatcaaga cagtttgtta taaatgaaag
    10681 taatattaca cgtttggact ggccaatgag cgaagaacgt tctgtattac gaatgaattt
    10741 gatcagcgga ctattagatg atatcagtta taacactgcc cgaaaaaata cagagattgc
    10801 tttatatgaa attggtcggg tgttcttcca agaaaatgat ccacgtacac atctgccgca
    10861 agaagtaaaa catgcagcaa tcgctatttc tggtatttgg gaagaaaaag attggcagac
    10921 gaaagctcaa aatgtagact ttttcaccat caagggtctt ttagaaaact tatttgaaca
    10981 actaggcatc actgaagatg tccattatca aacagtgaca gaaatgaagg aaatgcatcc
    11041 tggaagaact gctgcgattt accttggcga aaaatttatt ggttttgtcg gtcaagtgca
    11101 tccaacgatt acaaaaagtt atgatattcc agaaacatat gttgctgagt ttgatttatc
    11161 tgctatagtg gaagctgctc aaaaagggat cgttttcgaa gcagtgacaa aattcccagc
    11221 agtcagccgg gacatcgctt tgcttgtaaa agaaactgtg acaaatcagg aattaacaga
    11281 agttatccgt tctgctgccg gaagattttt aacagatatc caattatttg atgtctatca
    11341 aggagaaaac attgaaaaag gacataaatc catggcgtat agcctgacat tcgtcaaccc
    11401 agaagcaaca ttgacagatg aagaaatcaa taaagcaatg gaaaaagtcg aaaaagcgtt
    11461 ggtagaaaac ctagaggcaa gtattcgcta agaaggaaaa tatagtaagt aacgatcaag
    11521 tagcttttga agaccataca tttgaaaaaa agatgtgaca caacttcgtc acatctcttt
    11581 ttttgatttt aaaaaaggaa tagcacagag acgagataaa aaaacaggcc tttacagcct
    11641 gcttttttag agtaaatgaa ttaatggaag taattgattc ccattgctga ttttacttca
    11701 gaaagtgttt gtgcagctac tttagcagct tcttcactac ctttacgtaa gatttccata
    11761 acagctgaag gatctttttc caattcttct cggcgcgcac ggatcggtgc aaattcagct
    11821 tccaatacat caatgaggta tcgtttgatc tttacatcac caagtccgcc gcggcggtaa
    11881 tgagctttca tttcttcaat tgcttcttta tctgttccga atacatccaa gtaggtgaag
    11941 accatattcc cttctacttg tccaggatct tgtacatgga tgtggtttgg atcagtatac
    12001 atactcatga cttttttctg taagacatcg gcaggatcgg agatataaat accgtttcct
    12061 aacgatttac tcattttgcc atttccatcg attccaggta atctacccat tccttttggt
    12121 gggaatacgc cttttggttc caccaagact tcaccatatg tatgattgaa gctttgtacg
    12181 atttcctgtg tctgctctag cattggtttt tgatcctcac caacaggtac aagattcgct
    12241 ttgaatgcag tgatatctgc tgcttgagaa acaggataga taaagaatcc tgtaggcacg
    12301 ctttcaccga attttttttg ttcgatttct gttttgacag tcggattgcg ccgaacgcgt
    12361 cctacgctga ctaagttcaa ataatacatg gttaattcag ctaattccgg aatttgtgat
    12421 tggataaata aagtagattt tgcaggatct aatcccacgg ctaaatagtc taaagcaact
    12481 tgcaagacat ttgatgaaac cttctcagga tttttagcat tatctgtcag tgcttgcatg
    12541 tcagcaatca tgacaaacag ttggttgtct tcatctgcct gcatagccac tcgggttttt
    12601 agagaaccga cgtaatgccc taaatgcagc ttcccagttg gtcgatctcc cgttaaaata
    12661 atatttttca aaaaagacac ctctttacga tttgtaagtc tgagcactta atatcttacc
    12721 gtttttcctg aaaagaaaca acagttccta aggaaaaaac aaggaaagag gataaaataa
    12781 ctaatagatt agaaatggaa gaaatattta tgggagaata
//
LOCUS       DADVXK010000078        12740 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.079, whole genome shotgun sequence.
ACCESSION   DADVXK010000078 DADVXK010000000
VERSION     DADVXK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.079"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            99..542
                     /locus_tag="KB909_002083"
     CDS             99..542
                     /locus_tag="KB909_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6838090.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="KB909_002084"
     CDS             complement(548..1732)
                     /locus_tag="KB909_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBB6838091.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="KB909_002085"
     CDS             2000..2698
                     /locus_tag="KB909_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6838092.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="KB909_002086"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="KB909_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBB6838093.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="KB909_002087"
     CDS             complement(3508..4041)
                     /locus_tag="KB909_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838094.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="KB909_002088"
     CDS             complement(4338..6719)
                     /locus_tag="KB909_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6838095.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="KB909_002089"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="KB909_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBB6838096.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="KB909_002090"
     CDS             7420..7959
                     /locus_tag="KB909_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBB6838097.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="KB909_002091"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="KB909_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBB6838098.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="KB909_002092"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KB909_002092"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="KB909_002093"
     CDS             9066..10232
                     /locus_tag="KB909_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBB6838099.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="KB909_002094"
     CDS             10278..11774
                     /locus_tag="KB909_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBB6838100.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="KB909_002095"
     CDS             11855..12538
                     /locus_tag="KB909_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6838101.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3607 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggcgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt
//
LOCUS       DADVXK010000079        12736 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.080, whole genome shotgun sequence.
ACCESSION   DADVXK010000079 DADVXK010000000
VERSION     DADVXK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.080"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="KB909_002096"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="KB909_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6838102.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="KB909_002097"
     CDS             complement(322..891)
                     /locus_tag="KB909_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBB6838103.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="KB909_002098"
     CDS             1077..1979
                     /locus_tag="KB909_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6838104.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="KB909_002099"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="KB909_002099"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBB6838105.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="KB909_002100"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="KB909_002100"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBB6838106.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="KB909_002101"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="KB909_002101"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBB6838107.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="KB909_002102"
     CDS             8547..8732
                     /locus_tag="KB909_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBB6838108.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="KB909_002103"
     CDS             complement(8794..9990)
                     /locus_tag="KB909_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6838109.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="KB909_002104"
     CDS             complement(10160..11596)
                     /locus_tag="KB909_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6838110.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="KB909_002105"
     CDS             11889..12698
                     /locus_tag="KB909_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6838111.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4010 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaat
//
LOCUS       DADVXK010000080        12670 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.081, whole genome shotgun sequence.
ACCESSION   DADVXK010000080 DADVXK010000000
VERSION     DADVXK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.081"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            142..987
                     /locus_tag="KB909_002106"
     CDS             142..987
                     /locus_tag="KB909_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6838112.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            1178..2365
                     /locus_tag="KB909_002107"
     CDS             1178..2365
                     /locus_tag="KB909_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6838113.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            2371..2727
                     /locus_tag="KB909_002108"
     CDS             2371..2727
                     /locus_tag="KB909_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBB6838114.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            2729..3067
                     /locus_tag="KB909_002109"
     CDS             2729..3067
                     /locus_tag="KB909_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBB6838115.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    3143..3399
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3462..4496
                     /locus_tag="KB909_002110"
     CDS             3462..4496
                     /locus_tag="KB909_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838116.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            4489..5175
                     /locus_tag="KB909_002111"
     CDS             4489..5175
                     /locus_tag="KB909_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838117.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            5199..6047
                     /locus_tag="KB909_002112"
     CDS             5199..6047
                     /locus_tag="KB909_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6838118.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            6244..7017
                     /gene="sufC"
                     /locus_tag="KB909_002113"
     CDS             6244..7017
                     /gene="sufC"
                     /locus_tag="KB909_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBB6838119.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            7030..8316
                     /gene="sufD"
                     /locus_tag="KB909_002114"
     CDS             7030..8316
                     /gene="sufD"
                     /locus_tag="KB909_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBB6838120.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            8313..9548
                     /locus_tag="KB909_002115"
     CDS             8313..9548
                     /locus_tag="KB909_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6838121.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            9535..10005
                     /locus_tag="KB909_002116"
     CDS             9535..10005
                     /locus_tag="KB909_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBB6838122.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            10010..11401
                     /gene="sufB"
                     /locus_tag="KB909_002117"
     CDS             10010..11401
                     /gene="sufB"
                     /locus_tag="KB909_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBB6838123.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(11499..12641)
                     /locus_tag="KB909_002118"
     CDS             complement(11499..12641)
                     /locus_tag="KB909_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6838124.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
BASE COUNT         4057 a         2373 c         2765 g         3475 t
ORIGIN      
        1 agacagctga ttgtcttcat ctaagttact agttggatca gcaactgttt tgttgtacat
       61 ttctattata gatggttttt tgtatattta aatcaaatag tttttatagt aattatcata
      121 aaaagttatg gaagtggtgc catgtttaag ttattaacga cttttcgagc agtatatgaa
      181 acaagaaatt tttccagagc agcagaagta ctgtttttat ctcaaccagc agtctcgaat
      241 caaatcaaac agttggagcg ggaattgaat atcgatcttt ttcaacgtaa cggaagaaaa
      301 gagatgcttc caactaagca agccgactta ttatatgaac ggacactggt tttgttagaa
      361 gaatgggaag aaactcagca aaaattgctc aatgaacaaa atgaagaaga agtatgtcgg
      421 atcgttgctt cccacacctt tgctgtctat cttttgcctc agttgatgaa acatctgatc
      481 aaaaggtttc ctaaagtgca ttttgagatc gaaatcacga attctcatga atcattagaa
      541 caagtagcga aacatgaatc cgattttggt tttatcgaaa agccattaga gacttccggc
      601 gtacaaagat actctttgat ggaagaccag ctagtcatcg ctggggaccc aaaaagcaaa
      661 ttgtggcttg taagagaagc aaactctggt gtttttcatt acacgcagcg ttattttgaa
      721 gagatgaata tccaagataa gaagatgatc gtgaaaagta acgatgtaat tgttgcgttg
      781 ctgaaggaag gaatcggtcg ctcgattttg tctaagcgct ctgttccaga aaatgtgcca
      841 atgactccgt tgaatttcca tcgatatttt tatttcatcc aacgaaccaa tctggtttct
      901 gatcagctgc tagagattgc cgaagagatc cttcgataca atgaaagcac agaaacttct
      961 cacagcgagg agaatctcag ctggtagata attgcatgta tcaaaaaaag ttctatgata
     1021 cactaaagat aagcagtagg cttttgtact gcatttgctc aagcaactgc acaaacggaa
     1081 agttaatttt tcccaaatgt ctatggaaag actttccatt atctaactgg accgctataa
     1141 taatcagcag tatggttttt aagaaaaggg atgaaacatg gaaaaaaaat taaaagcttc
     1201 gaacgataat cgtattgatt atggcgtgat tttaccagtc tttctgttat gtttgattgg
     1261 tctgctctca ttatatgtag cacttagcca tgatccgaac aatccagcag tcttgaaagg
     1321 cgtagggatg caagttgtct ggtatttagt tggagcggca gcaatcgttg tcatcatgca
     1381 tttgaattcc aaatggatct ggaaactgac tccttacctt tatggtttgg ggttagtggt
     1441 aatgggactc ttgctcaaat tctatgatca gaatttagct gcttcaacag ggtctaaaaa
     1501 ctggtttcga ttcggtgcgt ttactttcca gccagcagag ttgatgaaga ttgcgtacat
     1561 cttgatgatg gcactgatcg taactaaaca taatacgcaa gtaaaagaac ggacgatgaa
     1621 atcggacttt tggctgattg ggaagctctt gatcgtgaca ataccggttt tagcattgat
     1681 catggcccaa gatgactttg gaacgatgct tgtctttctt gcgatctttg gcgggatttt
     1741 cctgatgtct ggaatctctt ggcgcatcat cgcacctgta gtaatcttgg cagtagtcgt
     1801 tggagcagga acgatcttct tggttacgac tgaaggcgga agagacttgc tttataaagt
     1861 tggattcaaa tcttatcagt ttgcacgtat tgattcatgg ctggaccctt tccatgatac
     1921 gtcaggaatg agttatcagc cggcccaagg acttttggca attggtaccg gtggcttgtt
     1981 tggtaaagga ttcaacgtaa gcaatatcta tgtgcctgtt cgtgagtccg atatgatttt
     2041 taccgttatc ggtgaaaact tcggctttat cggtggtgca ttcgtcattt tcttgtattt
     2101 tattttaatc tatcgtatga ttcgggtgtg tttcgatacg aataatgaat tttacgccta
     2161 tatcgcaagc ggtttgatca tgatgctgct gttccatgtc tttgagaata ttggagcaaa
     2221 tatcggatta cttcctttaa cagggatccc attgcctttc attagtcagg gaggatcctc
     2281 gattttaggg aacatgatcg gtatcgggtt gatattatcg atgagatacc aaaatgaagc
     2341 acctgcaaga tcttcaagga ggtaagaaaa ttgtacacct tttactggta cccgaaatgt
     2401 tcaacatgca aaaaagccaa agcgtggtta gaccagcatg gcgttagtta tcaaaccgtt
     2461 gatatgatca aagaagtacc gaaggcctca acgattgaga cttggctaga aacgagtcaa
     2521 gtaccaatcc gtcgcctgtt caacacaagc gggatgaaat atcgggaact tggactgaaa
     2581 gatcaagtag gcgagtttac ggcttcaaaa gcgagccaag tcttatcgac agatggtatg
     2641 ctgatcaagc gaccactgat cttacgagag gaccagcttg ttgcaattgg attcaatgaa
     2701 aaaatttatg aaggagaact gatataaaat ggcaggcaag catttgaaga aaaaggacaa
     2761 cctttggatc ttatttaatg gaaaagaata ctgtgttggt ttgacaaatg aagcgcaaga
     2821 agaacttgga gacatcacgt ttgccaatct gccaaaagca ggacaatcgc taaaaaaaga
     2881 tgaacctctg atcgaagttg aagcggaaaa agcggtcaat gaatttgcca gcccgctaac
     2941 gggtacagtt tcttctgtta atgataaaat cggtgaagat atcaatatct tgaatgattc
     3001 agatgaaatg aatgcgtgga tcttaagttt caaagatgtt gatccaaaag aatttgacga
     3061 attataaaat cagaaaatca cttgaaaaaa gttgacactg attcttccag ttgctataat
     3121 cataagcaat cctatatgaa acgagaaagc tttgaaaaga agagtacatg tcacggacgt
     3181 ttgaagagag ccctgtttgc tgaaaatggg taacgaaaat gagatggaag atggtcttag
     3241 agcagagtaa gcgagcgtaa gcaaacttac tacgggagtg cccgttacag cgcgacagta
     3301 tacggaaaga agctaagtcc aagtactgga agaggctgtt attgcgaagt aacggtaaat
     3361 caaggtggta acacggaagt tcaagctttc gtccttttgc ttaaggcaag agggcgaagg
     3421 cttttttgtt tgaaaaatta taagagaaag atgtgaatgg catgtcatta atccaactaa
     3481 cgaatgtcaa aaagacattc aatgggaaaa acggaaacat ccaagccgtc aatgacgttt
     3541 cactaaacgt tgaaaaaggg gatatttatg gaatcgtcgg ctattctggc gcaggaaaaa
     3601 gtacattagt ccgtctcctg aatggacttg agcttcccac gagcggcgaa gtgatcgtaa
     3661 acgatcaaga tattacaaaa ttaaaaaaca aagaattacg tacattccga aagaaaatcg
     3721 gtatgatctt ccagcatttc aacctgttat ggtcaagaac tgtacttgaa aatatccagc
     3781 tgccgctgga attagctggc gtaccaaaga gcaaacgtaa agaacgggca gaagaactgt
     3841 tgcgtttagt cgggttagaa ggacgcggac aagcatatcc ttcacaactt tccggcggac
     3901 agaaacaacg cgtcggtatc gcacgagcat tggcaaatga tcctgagatc ctgctttgtg
     3961 atgaggctac tagcgcattg gacccgcaaa caacagaaga agtattagac ttattgttag
     4021 cgatcaataa gaaattgaat ttgaccatcg tcttgatcac acatgaaatg aatgtgatcc
     4081 gcaaaatctg caacaaagtc gctgtgatgg agttggggaa agtcgtagaa gaaggagacg
     4141 tattgactgt cttcagacaa ccgaaaaaag aagtaaccaa acgctttgta caacaagaca
     4201 tcgaaccaga agctgattcg acagaactat tagctgaact catcaaagaa aatccaagcg
     4261 gccgtttggc aactttgacc tttagcgaaa gaaatgccaa cgagccagtc atttcccaag
     4321 cgattcgacg ctataacatc gatgtcaacg ttgtgtatgg aaagatcaaa caagtgaaag
     4381 aaggttcctt tggttcattg actgtcttga tgactggtga aaccaaagaa ttagatcaag
     4441 cagaagtgtt catcaaagaa caaggagtag gaattgaggt gatccatcgt ggataaaagc
     4501 ttttcagaaa catatctaga ttttaaacaa atcaacccgg aaacgatgaa tcaggctatc
     4561 cttgatacac tatatatgac attaatctca atggtcttag tgacgatcat cggattagtt
     4621 ttgggattga tcctttactc tattggacgc aaaaacaaac cgtatgctcg aatcatttat
     4681 ggaatcgtat cgatcatcag taatattttc cggtcaacgc catttatgat cctgatggtt
     4741 ttgatcattc catttactaa agcaatcgta ggcactatgc taggtgcgca agcagccatt
     4801 ccagctcttg ttttatccgc agcaccattt tatgcccgtc tagtagagat tgcttttcgt
     4861 gaagtcagcc ctggtgtact ggaagcagca gatgcaatgg gagcaagtta ctgggaaatc
     4921 atctggaagg tcttgatacc tgaaagtatt cccgcattga tttctggatt aacagttaca
     4981 acgatctcga tgatcggatt tactgcgatg gccggcgcga tcggcgcagg tggacttgga
     5041 ggtcttgctt ggcaggaagg ctaccagcgt ggtaatctaa cagtgacatt cgttgcgact
     5101 ttaattattt tactaatcgt atttatcgtt caaggaatcg gtgatttctt aactaagaaa
     5161 acagacaaaa gataatagga tataggggga tgtaggatat gaaaaagaaa atttttggat
     5221 ttgcagcagc gcttttgctg actgtaggat tagcagcatg cggtaacaac agcgacagca
     5281 aagattcagc aaataaagca gacgacacga cattgaaagt cggcgcttca ccgacaccgc
     5341 acgcagagat tttggaacat gtgaaaccat tattgaaaga tgaaggaatc gatcttgaaa
     5401 tcgtcaaatt cgatgactat gtattaccga accaatcttt ggaagaaggc gacattgatg
     5461 ccaattactt ccagcatatt ccttatttga acaaagaaat caaagaaaaa ggatatgact
     5521 ttgtcaatgc cggtgctgtc cacatcgaac caatgggctt gtactctaaa aaagtcaaag
     5581 atgtttccga attaaaagat ggtgcaacaa tcattacttc aaattctgaa tcagactggg
     5641 gacgcatcat cacaattcta caagatgctg gcttagtcaa agtcaaagat ggagtagatc
     5701 tggaaacagc aacattcgat gatattgaag aaaaccctaa gaacttgaag ttcaaccata
     5761 cgatcgaccc atcactttta gcttctacgt accaaaatga tgaaggtgac ctagttgcaa
     5821 tcaacgcaaa cttcgcttac ggcgcagggt tgaatccatt agaagatgcc gtattgcttg
     5881 aaaaggacaa ctctccttac gtgaatatta ttgcgactcg taaaggtgat gaagacagtg
     5941 acaaaatcaa aaaactgatt gaagtgcttc accgcaaaga agtccaagaa tggatcacag
     6001 acaaatgggg cggctctgtt aaaccagtaa aggctgatgc aaaataaggt atggaacaaa
     6061 aaagatgaga aataagtctg taatggctta tttctcatct tttttatacc tattctaatt
     6121 tagaaatcaa aattgtttaa taataaataa aagatatttg attttagtaa ggaaggtcat
     6181 tgcgcttcat tctcaattag tctaaaatga gtgagaacga aagagaattt gggggtataa
     6241 tgcatgtctg tcttagaaat aaaaaatcta catgtgtcga tcgaggaaaa agaaatcctt
     6301 aaaggcgtaa acctaacaat gaaaaccgga gaaatccatg ccatcatggg acctaacggc
     6361 acaggaaaat ctaccttatc tgccgctatc atgggcaatc caaactatga agtaacagaa
     6421 ggcgaaattt tgtttgacgg gaaaaatgtt ttagacttgg aagtagatga acgtgcgcga
     6481 cttggcttat ttttagctat gcaatatcca agtgagatac caggtatcac gaatgcggaa
     6541 ttcatgcgtg cagcgatcaa tgcgaaacgt gatgaaaacg acaaaatttc tgttatggca
     6601 tttttgaaaa agttagatga aaaaatggct ttactaaata tgccagaaga aatggctgaa
     6661 cgttatctga acgaaggttt ttctggcgga gaaaagaaac ggaatgagat cctgcaattg
     6721 ttgatgttag aacctacatt tgcaatttta gacgaaatcg attcaggtct ggatatcgat
     6781 gctttgaaag tcgttgctaa aggagtaaat gaaatgcgcg gagacaattt cggtgcattg
     6841 atcatcaccc actatcaacg attattgaac tatatcacac ctgatgtcgt tcacatcatg
     6901 atggaaggcc gagtagtcat gacagggaat gctgacctag ctaaacgtct ggaagcagaa
     6961 ggctacgctg gtatcagtaa agaattagga atcgactata aagaagaaga agcgtaaggg
     7021 ggagcaagaa tgaaagaaaa aaactggctc gattatcttg acgcggtaaa tgatttttct
     7081 ttaagtaaag gcgaacctga ttggatgaga accttccgtc aagacgcact agcgaaagca
     7141 gatgaactgc cattgccgca tatcgatcgg gtgaaattcc atcgctggtc gttatttgat
     7201 gtgaaagaaa cacaaaccat cagtgaaaca ggcacgattc cggcatttga tgcaatgaaa
     7261 gacaatcctg tgcttgtcca acaaggttca tggacgattt ttgaacaact gcctgtggaa
     7321 ttagcagaaa aaggagtcat ttttaccgac ttgttcactg caatgatcga atatccagaa
     7381 ctagtccaag aatattatat gaaaaaagca gtaaacatga acgaagacca attgactgca
     7441 ctccatgtag cttttatgaa cagcggtatt ttcctgtatg tgcctaaaaa tgtcgtgatc
     7501 gatgaaccac tcgagtcctt attcattcaa gatggcgcat ccgatgagca cttcttcaag
     7561 catgtgttga tcgtggcaga tgaacatagt gaattttctt atctggaacg tttccagaca
     7621 accaaagaac aagtagcaaa atcatcaggt aatatcatcg tggaagtcat cgctaaagct
     7681 ggttcaaaaa tcaaatattc agccgtagat caattaggag aaaatattac ttcttatatg
     7741 aatcgccgtg ggcacatttt acgagatgct tctgtcgact gggcaattgg tgtcatgaat
     7801 gacggtcatg tgatcgctga ctttgactca gatttagcag gagaaggtgc acacgcagaa
     7861 gtcaaaatcg tggcaatcag ctcgggcaga caaatccaag gaatcgatac acgagtaacc
     7921 aataaagccc ctcatacgat cgggcatatt ttgcaacacg gagtgatccg agaaaaagga
     7981 acattgacct ttaatggtat cggccacatc ttgaaagggg caaaaggtgc agatgcccaa
     8041 caagaaagtc gtgtcttgat gctttctgat aaagcacgtg gtgatgcgaa tcctattctt
     8101 ttgatcgatg aaaacgaagt aactgctgga catgctgcca gtgtaggacg agttgatcca
     8161 gaagaaatgt actatctgat gagtagagga ttgcataaag aagaagcaga gcgcttagtg
     8221 attcgaggat tcctcggttc tgtcttaaca gcaatccctg tagaacaagt tcggaaagaa
     8281 ttagtcgaag taatcgaagg gaagttgaat ggatgatcga tgctaaaaag ctacgcaatg
     8341 attttcctat cttatttcaa gacgtcaatg atgaaccttt agtttatctg gataatgcag
     8401 cgacgaccca aaagccaaaa caagtactcc aggcattagc gtactattac gaacacgata
     8461 acgccaatgt tcatcgcggt gtccatacgt tagcagaacg cgcgacccat gattatgaac
     8521 aagcaagaga aaaagtacgg gcgttcatcc atgcaaaaga aacagcagaa gtgctgttta
     8581 ctcgtggtac gacgacaagc ttgaattggg tagccagaac cttcggcgac cgctatatca
     8641 aagcaggaga cgagatagtg ctctcttaca tggaacatca ttctaatgtt atcccgtggc
     8701 agcagttggc aaaacgaaca ggtgctgtct tgaaatatat cgaactaaca gaagaaggct
     8761 tcctggatat ggaggatgca gcgaaaaaga ttacggacaa aaccaaaatc gtctccattg
     8821 ctcatgtatc caatgtctta ggtgtcttca atcctgttca agaattagct gaacttgtcc
     8881 atgaaaacgg cggggtcatc gtagtagatg gtgctcaatc tgccccgcac atggccattg
     8941 atgtccaagc actagactgt gatttctttg ctttcagcgg acacaaaatg tgcggaccaa
     9001 caggtattgg tgttttatat ggtaaacgaa aatggttaga agaaatggaa cctgttgaat
     9061 ttggtggcga aatgatcgat tttgtcgaat tatacgacag tacatggaaa gaactacctt
     9121 ggaaattcga agcagggaca ccaaatatcg ccggcgctat cgcattaggc catgcaatcg
     9181 attatttgca aaaactcggt atggacaata tccatcgata tgaagaagaa ctagccgctt
     9241 atgtgttgcc aaaattacaa gcaattgatg gattgactgt ttatggtcca caagacccga
     9301 attttcggac aggagtcgtt gcattcaatt tggatgggtt acatccccat gatgtcgcga
     9361 cagctttaga catggaaggg gtagccgtca gagcaggtca tcattgtgcg caaccgctat
     9421 tgaagtacct tgaagtatca gcgactgctc gcgcgagctt ttatttctac aacacaacgc
     9481 aagacgccga ccgtttagtt gaagcaatca tggcaacaaa ggagtttttc caacatggga
     9541 ctatctaaat tagacaattt ataccgtcaa gtgatcttgg atcattcttc ccatccgcat
     9601 catcgtggaa gcttgactga ctcgacaagc aagatcgaat tgaacaaccc cacatgtgga
     9661 gatgtgatcg aattgcaagt cgatgtaaaa gacggaatca tcaaaaatat cgcctttgac
     9721 ggcagtggct gctccatcag tacggcaagt gcctcgatga tgacagacgc cgtcatcgga
     9781 aaatcaatag aagaagcaga acatttaact gtagactttc tacagcttgt ccaaggaaaa
     9841 gaagtcaaag atcccgacca attaggcgat gctgctatgc ttggtggtgt agctaaattt
     9901 cccgctcgga tcaaatgtgc gacacttgcc tggaaagcac taggaaaagc aatggaaaac
     9961 gatggtaccg cagctttcca tcattaccac aaggaagagg agtgagaaca tgggcgtacc
    10021 agaattagaa gaatataaat tcgggtttca cgatgatgtc gaaccggttt tcagtacagg
    10081 agaaggcttg acagaagaag tgatccgtga gatgtcaaga atcaaaggcg aaccagaatg
    10141 gatgcttgaa ttccgtctga aatctctaga aacatttaac aaaatgccaa tgcaaacatg
    10201 gggccccgac ctttcagaca tcgatttcga tgccatcaaa tattaccaaa aaccaagtga
    10261 caaacccgct cgtgactggg aagacgtacc agaaaaaatc aaagatacat ttgaaaagat
    10321 tggtatacca gaagctgaac gagcttatct agccggtgct tccgcacaat atgaatcaga
    10381 agtcgtgtac cataatatga aagatgaatt cgaaaagtta ggaatcgtct ttactgacac
    10441 tgactctgct ttgaaagaat accctgaatt attcaaagag tacttttcaa aacttgtacc
    10501 gccaaccgac aacaaattag cagcgctgaa ttcagccgta tggtcaggtg ggacctttat
    10561 ttacgtgcca aaaggcgtca aagtcgatgt tccattacaa acgtacttcc ggatcaatgc
    10621 ggaaaacacg gggcaattcg aacgtacgct gatcattgtt gacgaaggag caagcatcca
    10681 ctatgtcgaa ggttgtacgg cacctactta ttcaagtaac agcctgcatg ccgccatcgt
    10741 agaaatcttt acaagaaaag atgcgtattg ccgttacaca acgatccaaa actggtcaga
    10801 caatgtgtac aacttagtaa ccaaacgagc aaaagcatac gaaggcgcaa ccgttgaatg
    10861 gatcgacgga aacctaggtg caaaaacaac gatgaaatac ccaagtgttt acttagatgg
    10921 aaaaggtgca cgaggcacca tgctctccat cgcctttgca ggagcaaacc aaatccaaga
    10981 tacgggtgca aaaatgatcc acaatgcacc aaatacatct agctctatcg tctctaaatc
    11041 aatttcaaaa gacggcggag aagtaaacta tcgaggacaa gtaacctttg ccaaaaacag
    11101 tgcgggttcg atctctcata tcgaatgtga cacgatcatc atggacgaat ggtcgaaatc
    11161 cgatacgatc ccattcaatg agatccacaa cagccaagtc tctttagaac acgaagccaa
    11221 agtctcaaaa atctcagaag aacaactcta ctatctgatg agccgaggcc tgaccgaatc
    11281 tgaagcaact gaaatgatcg tcatgggctt tgttgaacca ttcaccaaag aacttccaat
    11341 ggaatatgca gtcgaactca atcgattgat cagttatgag atggaagggt ctgtaggtta
    11401 ataactattt cattgctcga aacgttgata ttaaagcgtt tcgagcgttt ttttatttgt
    11461 attttaatgg ttggctacgt ttttggctac gtttggaatt attcgcccat aaattttgca
    11521 aatcggtcac cagttttctt aacagattgt ggtgtgacat gagcatagat attcatggta
    11581 gttttaatat ctttatgacc taatcgttcc tgtacttctt ttatcgacgc accactttca
    11641 aacaataagc tacagtgggt atgcctaaat ccatgtggag taatttgagg ctccatcggt
    11701 gtctttttgt aaatccagtc taaccaatcg tttactactt gggggtagta caacttgttt
    11761 gtgtttgtag tgaaaagaaa ctgttttggt gaattcgtgt tatagccata taagatcatt
    11821 attttcattt gttcttgttg ccaaatacgc agttgtttaa gtgtaaaatc atcaagctga
    11881 atcgttcttg atgaattttt agttttaggt acttgtagaa ctacttgatt aaactcgtct
    11941 tgagcgatag ttttaccaat tgttattgtt ttattgaaat agtctatatc ttcccattga
    12001 agcgccaatg cttcgctttt acgcattcct gtataagcta ataaacggaa aaaagtgtac
    12061 agtttaactg aattattttc tttagtattc tgtaaaaaca gttgtaattg atctttcgtg
    12121 taaaacttca agggttgttc ttcttcaatt tttcttggaa gcaatgtttt agacatagga
    12181 ttatccttac agacttccat tgctactcca aatttaaata tttgagcagt tgtttttctc
    12241 aagaaaccat attgttttaa tgttttgtgc cattcattca cctgtttttg gcaatagcta
    12301 acacttattt tatccaatcg taattcccca aaagcaggta atatatggtt tttgcaaaaa
    12361 cgttgagcaa cggcaacaga agacggtttt actcttgttc tgtagttatc aatccataat
    12421 tcatacaact cttgaaaagt tgtaacattg attttaaact cttgtttttc tttaaagtct
    12481 acaagtagtc tattaagtgc tgtttgcgcc tcagcttttg atttgaatct tctacgcttt
    12541 gtacgtatat cttttccagt cttgggatct ttccctaaat aagtttcaaa tccccaatat
    12601 ttttcgccat tttgtaattt ataactaaaa aatgttgcca tttgattctc tccttacttc
    12661 attattgcag
//
LOCUS       DADVXK010000081        12645 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.082, whole genome shotgun sequence.
ACCESSION   DADVXK010000081 DADVXK010000000
VERSION     DADVXK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.082"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            92..370
                     /locus_tag="KB909_002119"
     CDS             92..370
                     /locus_tag="KB909_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838125.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            389..1597
                     /locus_tag="KB909_002120"
     CDS             389..1597
                     /locus_tag="KB909_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838126.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(1745..2110)
                     /locus_tag="KB909_002121"
     CDS             complement(1745..2110)
                     /locus_tag="KB909_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBB6838127.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(2257..3030)
                     /locus_tag="KB909_002122"
     CDS             complement(2257..3030)
                     /locus_tag="KB909_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6838128.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(3204..4064)
                     /locus_tag="KB909_002123"
     CDS             complement(3204..4064)
                     /locus_tag="KB909_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBB6838129.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(4064..5482)
                     /locus_tag="KB909_002124"
     CDS             complement(4064..5482)
                     /locus_tag="KB909_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6838130.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(5539..5988)
                     /locus_tag="KB909_002125"
     CDS             complement(5539..5988)
                     /locus_tag="KB909_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6838131.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(6433..6696)
                     /locus_tag="KB909_002126"
     CDS             complement(6433..6696)
                     /locus_tag="KB909_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBB6838132.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(6795..8090)
                     /gene="rho"
                     /locus_tag="KB909_002127"
     CDS             complement(6795..8090)
                     /gene="rho"
                     /locus_tag="KB909_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBB6838133.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(8087..9358)
                     /locus_tag="KB909_002128"
     CDS             complement(8087..9358)
                     /locus_tag="KB909_002128"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6838134.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(9523..10392)
                     /locus_tag="KB909_002129"
     CDS             complement(9523..10392)
                     /locus_tag="KB909_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBB6838135.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(10684..12294)
                     /locus_tag="KB909_002130"
     CDS             complement(10684..12294)
                     /locus_tag="KB909_002130"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBB6838136.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
BASE COUNT         3549 a         2681 c         2196 g         4219 t
ORIGIN      
        1 gtaccttttt ccatcactta tgcgattttt ttcctttttt ttattcgtta tactgcagaa
       61 gtaaaatttt ttaagaatag agggaaaaaa catgaattac tggatgaaca caatcattaa
      121 tcgattagaa acagcatatc aaacaagatt tgatatgaaa gcttctttag tctttttaaa
      181 tgatgcgtat caaaactcga tcgaattgat caaagcagtg gatgagaatc caacaaacga
      241 atgcgaagaa tttttaaatc tgtttatgtc tacaagagat ttatttattc gccaacttgt
      301 tgatcgctat ccatccaatt atcacgatgt agaagttcaa atacaaaaat taaaagcata
      361 ttcagcttaa ggggaatgta taacatacat ggaaaagaaa ttatttaata aatattttat
      421 tggaatcaca ttgatcaatt ttattgtcta cctgatttat tatctgttga tggtcatcat
      481 ggcagtcatt gcgcaagaca ccttacacgc cagcttgagc caagcaggtt ttgcttctgg
      541 gatctatatc atcggaacat tgctggcacg cttattcatg gggaaacagt tagaactatt
      601 tggtcggaag tttaccttaa gaggcggcgc gatcttctat ctcctttcaa cattagcata
      661 tctttatacg ccaactatcg gggcattgta tttagttcga ttcttgaatg gattcggcta
      721 cggtacagtt tctacagcta caaatgctat cgttactgca tatatccctg catctaaaaa
      781 aggggaaggc atcaattatt atggattaag tactagttta gctgccgctg ttgggccatt
      841 tttaggaatg attttgctga atatgactga ttttcgtttc attatctggt tttcaattgt
      901 actggtcttc tttgttacga ttgcctgcct tgtctttcct gtaaaaaata ttccattatc
      961 tgaagaacaa aaaatatctc ttcgctcatg gaatatcaat agttttattg aaaagaaagc
     1021 acttttcatt acaggaattg cctttttgat gggtctttct tattcaagtg ttttatcatt
     1081 tttatcttct tatacaaaag taatccactt agttgctgct gggtcatttt tcttcgtcgt
     1141 atatgctttg gtcatcacat ttacacgtcc attgactgga aggattttcg atgtcaaagg
     1201 agaacaatac gtgatgtatc ctagctattt attcttaaca gcaggattat ttttactgag
     1261 tgtaacgacg aatagtgtga cattgcttat ctctggagca ttagtcggcc taggttatgg
     1321 tacgtttatg tcaaatggac aggctgtttg tttaaaaatc gtccgcgaac atcgaatcag
     1381 tattgcttta tctacctact ttattggttt agacctaggc ttaggcgttg gtccttattt
     1441 gatggggatg ctaaaatctc ttacttcatt tagaggattg tatgtgattg ccggagtcat
     1501 tccattgata tgtacagcac tctatcttgt taatggccga aaacatagtc atgaagcaga
     1561 gggcgaattg attgaatcat tgaaaaatga aatttgatct tgatgaatag ataaaaaaaa
     1621 ccgttcagat ctgaaaataa tctgagcggt tttttgagta aaaatagttt atgattattc
     1681 ttaattaaac atctatttat ttttaaagct ttcatttatc gataagaata gtttaactgt
     1741 tgatttattc cattttccgt tcatctggta cgatgccttg acttagcaac cacttgtgga
     1801 agaaccattc tgccacaccg atcaatagag caggaatcaa tactttcatc caaatatcga
     1861 ctgtatcatt cataaaatat agatagagcc acaagataac tgcagctgaa ccagcatctg
     1921 cgatcgtcgc tgcgatgttc cctactttac gtaagatcaa cagatcccct agcacataga
     1981 tcatgactac aataattacc ccaacaatcg ttgaatccat aaagctaaca ccgtataaac
     2041 ctgtcagcac gacccacaga atcgcccaga tcatgattgc cttcactacc aacgccttca
     2101 catgtttcat tttctgcact cctttctcct ggataaaaaa gtaagattat ctaacaagat
     2161 aaccttttca ttattatacc atcggctgag agaagcgagc aaagataagg tcctatctaa
     2221 aaatgaggaa gccacttaga acattcacgt aataatttat ccgtacagac attcgatatg
     2281 gtgttccttt actttcgcat actgttcttt tgtcagttct ttacttgtca ccagataatc
     2341 gatttcatga aaagcaatgg cttgatgcat gaatttatgt gcaatttttt gctgtgtaac
     2401 taaaacggca agccggtctg attgttttct aaaagctttt ttgaccattg cctctccttc
     2461 atgagtttct gttactcctt ggctgaaatc tagcccgcga caactcatta tcgctaaatc
     2521 cgcataatat gacaatgcat cgttataggc ttttgaaccg ttgattgttg ctcgtttcgg
     2581 aacaattgcc cctcccaata cagatacttt tgccgttgta tattcactca acatagcagc
     2641 tgtgacgatg ccattcgtaa tgatctgcaa accatcaaat cttgctaggt ttctgactaa
     2701 gtgtaaagag gttgtactgg aatccaagaa taagaccata tcatctcgaa tcaaagaaga
     2761 agctgtatct gcaatcttac gtttttctgt ttcttcttct aatttggtga tcttcatcag
     2821 gtaaggcacg tcaatttttc gattgtcaat aagcatggcg ccaccgcgaa ctctacggat
     2881 caatccactt ttttccagaa aaacaaggtc acgtttaatc gtggcttcgc tataatttac
     2941 taactcgatc aaatcggtga ctcttgcaaa ttggttgttt tttagataat tcacaatctc
     3001 ctgctgtcta ttctccactt cattcaacat aaaatcaccc catttacttt atatagtaac
     3061 aggaaaaaag aggttgtgac agaagtgatt ggcttcgaga aataagaaga aatttttcga
     3121 aaaaactact tctgaacatc gtgtgtggtt aagagggtat gacaagacta ttgtcatacc
     3181 ctcttgacca cacattttta tttttagtat aaactagcct tgcctactgt gttcaaaatt
     3241 tccattttat gtttgaccac ttcttgtacc tttttattag ctgctggata aattgcattc
     3301 ggctcgtaca tcgatggatt ttcactcaat atttctctca aagcattgaa aaagacgctt
     3361 ttaagatctg agctcaaatt cactttggca actccgtatt ttactgcttc gctgacttct
     3421 gcgtccggat tacctgaacc gccatgtaaa acaaatggaa gatcgatttg ttggttcaat
     3481 tctttcagta agtcgatatt taattttgga gttctgtttt tcggatacaa gccatgcgct
     3541 gttccaattg ctacagcaag tgtatcgatt cctgtttctt tcacaaaaat cttcgcttga
     3601 tcaggatctg tataaatgat tgtttcagca cctccttcag cagaaccatt attcccaatc
     3661 gttccaagct cagcctccac tgagacattt accgcatgag ctaacgcaac cacttttttc
     3721 gtaatctgta cattgtcgtc gaatgatttc aaagacgcat cgatcatcac ggaagaatag
     3781 ccgtttcgaa tcgcccgtaa gacatcttct atcgtaccgc catgatccaa gtggataacg
     3841 atcggcagtt tacttgtata agcataggct cttactgccg caacaaactc atcacttaaa
     3901 taggcgattt catcaggatg aatttctaag attactggtg cttctaatct ctctgcttct
     3961 tcgatgattg ctttcatcat atcatagctg caaatattga aggctggtac tgcaaattga
     4021 ttctctttag ccactttcaa taactctttc attgtatata acattacgct tccacctcat
     4081 ttgttagatt ttcatttttc gtccacttgt cttgtttttt ctctttcact gtttttttca
     4141 atagtccaag cataaaggct gtagtgactg tacctgatgc aattgccaag acatacatag
     4201 gtaaattgtt cataacattt ggaattagca tcacccaaat ccctccatga ggtgccattg
     4261 aagtaactcc tactgccatg gaaatccctg cagcgactgc tgaacctgtc atcaaactag
     4321 gtatcacgcg gatcgggtca gataccgcaa acggtatagc accttctgta atatacgaag
     4381 cgcctaaaat ccagcatgat tgacctgaag tccgttcttc tttggtaaat ttatgtttga
     4441 ataataaagt ggctaaagca atacctaggg gaggtgtcat tcctgcagcc atacaagcag
     4501 caatcggtgc atttactcca gctgacatca aaccgatcga gaaagtcgaa gtcgatttat
     4561 tgatcggccc acccatatca gctgccatca tgatcccgat aagtaatccg aacaatagcc
     4621 cggatgtatt tcccaagcta ttcagccaat ttgtcaaagc atccaacacc catgtgatcg
     4681 gttgttcaat cacaaatacc atcaaaagcc caataattaa gatcgataaa aaggggacga
     4741 caatcagctg ataaatagca gaaaattctt tttttacgct aattttattt gccagaaaat
     4801 cacagatata ccctgctagc acgccaccaa tcattccgcc aagaaaacct gaaccacctg
     4861 tagaggccag taatccggca acaattcctg gggcaaaacc tgcttttcca gcaatcgatg
     4921 tagcaatccc cgcgcctaac gcaggaacca tcatggcaaa cgctgtatct cctccgatcc
     4981 ttgaaaatgc agctgctaac acattatagt ctgctgagtt gggatcagcc gctgtaatcc
     5041 caaaggcaaa actcagtgcg atgatgattc cgcctgcgat cacaaatgga agcatgtaat
     5101 tcacaccatt catgaaatga ttatagattg tcggcttttt ctcatttgca gctggttctt
     5161 tttcattaga cacaacgaat acgccaatat ctctcaatgc ttcgtctatt actacttgcg
     5221 gttctttgat tgctcggctt gtagagacac gctttacttt tttcccggca aatcggtcca
     5281 attcgatttc tttatctact gcaagaatga ttgcatctgc ctctttgatt tcttgttcag
     5341 ataactgatt ttctgttttt acaccttgtg tttcgaattt tgcttgatgg tttagatttc
     5401 ttgctgttac ttctaatttt tctgccgaca tataagtatg agcaattcca gtcgggcaag
     5461 cagttacacc aacgattttc atgattattt tcctcctttt tcttcactat cgatactcgg
     5521 acaaagactc tactattttc attcttgact aatctgtctg atgatatctg ctggcgtagt
     5581 ggcttctttt attccctttc taaaatctgc attcatcaat cgtctggaga gtgtgctgag
     5641 aatctctaga tgcatatctg ctgatttttc aggaactacg atggcaaaaa tatattcaat
     5701 tggcatttca tctatcccgc tatagtccgt taatttggct gtatgaaaaa aacacagtgc
     5761 tggttttgtc acatatttgc tttttgcatg gggaatccca aatccatctt ctattcctgt
     5821 ggagatctcc tcctctcgtt tgaatagtgc cttaacgact ttttgaacat ttcttacctt
     5881 atttgttttt ttcaacacat cccctattcg ctcaaataat gatccttttg aatctatcga
     5941 tggatcgaaa acaatcagtt cttctgcgat caattgatca aacctcataa aaaacctctc
     6001 ccccacaaaa aatgttaacg ttttcttgga actgaggtca gtatagcatc gctagctgta
     6061 ccgttcaata ttatgaatga acagaggaaa aagacccatc atccgcgtgt ataagtcatt
     6121 aaaatgaacg atctagctca caaacaatcg caagtctata acaaaacaaa aagccttcct
     6181 tgaaaggaaa gcttagcttc taattttagg taaatggttt tttacttcga aataacccct
     6241 cttcatttcg ttaatataag gtgtttttat caagtggata attaaaacta tatactagtt
     6301 tttcattgtt ttgtgcatta tgatcctacg actttttcag catcaaacga agttttaaat
     6361 tggcaaaaaa cataaaaaaa cagactatcc ctatcagata gtctgctaaa cgttgagtta
     6421 tcagcgtttt tattattccg cagcgtttgc gtctttgaga ccgtattttt tgttgaaacg
     6481 gtccacacgt ccgtctgctt gtgtgaattt ttgacgtcca gtgtagaatg gatgtgagtc
     6541 agaagttact tcgacacgga tgactgggta tgtattaccg tcttcccatt caactgtttc
     6601 ttgtgaagtt tttgttgaac ctgacaagaa tttgaaacca gttgttgaat ccatgaatac
     6661 tactgggtgg taatctggat ggatgttttc tttcatgatt ttttcgctcc tttgccctgc
     6721 tccatttgct gaaccagagt tgatttgtcg atttacaaca ttaacatctt aacatgtttc
     6781 agtcaaggtt gcaattatct tttcagattt ctggtcggat tttttttacc aaaggagaca
     6841 tcttgaaatt ctttgaaaaa ttgctgattg ttttttgttt tacgcaaaaa gcggatcagt
     6901 tgttccgtat attctaatga atctccagtc atattttttc gaagtttcca aatttcttct
     6961 aattcttcac ttggcatcaa taattcttct tttcgggtac ctgatttttt gatatcgatg
     7021 gctgggaaga tccgacgttc agataattca cgtgaaagtt gtaattctag atttccagtt
     7081 cctttgaatt cttcatagat cacgtcatcc atacggcttc ctgtatcgac taaagcggtc
     7141 gctaaaatcg tcaaactgcc accttcttcg atgtttcttg ctgccccgaa aaatttctta
     7201 ggtttataca atgcggctgg gtcaatcccg ccactcaatg tacgtccgct tggtggaacg
     7261 actaagttat aggcccgagc aagtctagta atactatcca tcaagataac gacatctcgt
     7321 ttatcttcga ctaaacgcat tgcgcgttcc aatactaatt cagaaactcg agtatggttt
     7381 tgcggctgca gatcaaatgt agaagatacc acgtcgcctt tcacgcttcg ttctagatcc
     7441 gttacttctt ccggtcgttc atcaatcagt agaacgatta attctacttc cggatagttt
     7501 tcggtgatac catttgcgat ttcttttaat acagaagttt tccctgcttt tggcggtgcg
     7561 acgatcaatc cacgctgacc aaaaccgatt ggagaaaaga tatcgatcat tcgggtagat
     7621 agtctttgcg gtgttgtttc cagttgaagc tgtctttgcg gataaagagg tgttaaggct
     7681 ggaaaatgcg gacgttcttt tgcttcttcc ggatcttttc cattaacgct ttccacgtgc
     7741 atcaaaccat aataacgttc cgattcttta ggtggacggg cttttcctgc cactttgtcc
     7801 ccatttctca aactgaatcg tctgatttgt gaggcagaaa tatagatatc ttctgcactt
     7861 ggtccataat tgattggccg taaaaaaccg taaccatctt gaccaacgat atccaatatt
     7921 ccttccatat aataaaatcc ttgtttctct gcttgtgcac gaatcacagc tagagataat
     7981 tcctttttat tcatcttact gtaataagga attttaaatt ctttggcata actataaact
     8041 tcttttaacg ttttgttctc tagttctgcc attgtcaaat aatcgctcat tcagctccca
     8101 cttcctctat catttcaatt gatgccccta aggctgttag tttctcgata atatgatcat
     8161 aaccgcgtaa gatataatct acattgtaaa tcgtcgttgt cccttctgcc aatagtccag
     8221 caatcactaa acaagcacct gcccgaagat cagaagccac gacttctgtg ccgtgaagtt
     8281 tatttggacc attcacgatg atcatatttc cttccacggt aatatcagcg cccattcgtg
     8341 ctagttccgg cacatggttc acacgtttcg catagatcgt atcgatgatt tctgaagtgc
     8401 ctgtagtcat caatagtaac gcagtaagtg gctgctgcag atctgtggca aatcctggat
     8461 aaggataggt catgatgttt gcgggtttta attctttcga ggggtaaact tcgatttcat
     8521 cttcgctgat tttcatatgg acaccaattt cctgcaattt tgctataaag ctttccaaat
     8581 gttcaaagat cacatttttc actttgatac catttcctac tgcagctgct aatgctagat
     8641 aggttcctgc ttcgatgcgg tcaggaatca tgaaatgccg acagccatgt aatgtttcga
     8701 ctccttcgat acggatcaca tctgtacccg ctcctcgaac ttttgccccc atattattca
     8761 gtaaagttgc cacatctatg atttccggtt ctcgtgcagc gttttcaatt actgtctgtc
     8821 cttttgcttt tacagcagct aacatcacat tgatcgttgc tccgactgaa accacgtcca
     8881 tgaaaatccg attgccacgc aatcctttat tttctgtccg taaatacatg gcaccatgtt
     8941 catttgtcac ttcagcacct agagcttcaa atcctttgac gtgtaggtca atcggtctag
     9001 ggcctaaata acagccacct ggcaggccta ctaccgcttc gccaaattta ccaagcagtg
     9061 ttcccataaa ataataagaa gcacgcaaac tattgatttt tccgtgcggc atcggaatcg
     9121 atacgacttc tcgaggatcg atttctagta tgttgttgga aaaatggaca gttgcgccca
     9181 tgatctctaa aatttcaatt aatgaatgaa catcttgtat gtccggcaca ccttccaaga
     9241 tcactgggga atcagctaag attgcagctg gaatcaatgc gactgcacta ttttttgcac
     9301 cgctgatcgt tacttcacca gctaaaggtc ggtttccttt gattacgatt tttttcatct
     9361 gtttccacct tgtttattaa tcttttttca tggatatgct tgtattttat catagataaa
     9421 aaaaagaaac gagcatggtc tgccgtttta agtaaaaaag aatggagagc gacttcaaaa
     9481 gtcgttctcc attcctatat atcgtatctg ttatgtggat gcttacgctt tgttagctga
     9541 accgaaccag tcgatatgag atttagcatc ttcaacgatt gctgctttac ctggagctaa
     9601 taatttacga gggtcgaatc ctttaccttc tttatcttta ccagcttcga tatatttacg
     9661 agtagctgca gcaaatgata attggaattc agtgttaaca tttacttttg agatacccat
     9721 tgagatagct ttttcgattt gatcttgagg aatacctgat ccgccatgta atactaaagg
     9781 catgtctgga cctacagcat cagcaattgc ttgtaagtgg tcaaaagcta atcctttcca
     9841 gttttctgga tattgaccat ggatgttacc gataccgcaa gctaagtagt cgatacctgt
     9901 agcaaccatt tgtttgcatt cttcaatatc agctaattcg ccgttaccga tgattccgtc
     9961 ttcttctccg ccgattgaac caacttcaca ttcaactgag ataccttttg catgtgcttt
    10021 ttcaacaacg tctttagcta atttcaagtt ttcttcaaat ggtagatgtg aaccatcgaa
    10081 cattactgaa gtatagccta attcgataca ttccaaagca gcttcgtaat caccatggtc
    10141 taagtggata gcaactggaa cagtgatgtt cattgcttca actaaatcag tgattaaatc
    10201 tttacagatt ttgtaaccac ccatgtattt agctgcaccc attgatgttt ggataagtac
    10261 tggtgcttgt tttgcttcag ccgcttcaag gattgcttga gtccattcca agttgtttgt
    10321 gttgaatccg ccgacagcgt aaccgccttt acgagcagct tttaaaaatt cagctcctga
    10381 tactactggc ataataaaat tcctcctaag ttttgtaaaa ctaaatttgt taagacaatt
    10441 cttaaccaac gaccctattt taccaaacat ttcggtagtt ttctactaaa atcaatgaaa
    10501 atgaaaattt tcaagaagtt ttttgcaaaa aataaaatat ccaatagcgc tttaatcgaa
    10561 aaaagtcttt tgctttctat cttttttcct acaaataata acaaatcaga aaaagagaaa
    10621 agtgacaaga aaattgctta tccccttctc ttgctacttt tctctttcta tcaagttcaa
    10681 aaattatttt gtttcgtgat ctgctaatga tgctccgaca aatgctttga ttaatttttg
    10741 cgggcgattt ggacgagaaa tcaattctgg gtggaattgg catcccacaa agaatttttt
    10801 ctctggcagc tctacgattt ctactaaacg gttatctggt gagacacctg aaaagactag
    10861 cccttgttct tcaaacaatt gacgatattt gttattgaac tcatagcggt gacggtgacg
    10921 ttcttgcaca acatcggctc catcatatgc ttcagccgtc ttcgttcctt ttttgatttt
    10981 acatgggtat aatccaaggc gtaaagttcc acccaaattc tcgatgtttt cctgatcagc
    11041 cattaaatca ataatattgt ttgctgtatc tggattcgtt tcagctgatg acgcatcttc
    11101 taatccaacg acgttacgtg caaattcgac acaagccatc tgcataccaa gacaaatacc
    11161 taaaaacgga acgtcatttt cgcgagcata acgaatcgct tcgattttcc cttctactcc
    11221 gcgatcacca aatccaccag gaaccaagat tccatctgcg tctttcaaac gttcttctac
    11281 attttctctc gttaattctt gtgctttgat ccaatcgatc tcgatgtctg aattataggc
    11341 gaaaccagaa tgtttcaatg cttcaactac tgagatatat gcatctggta actcgacata
    11401 tttaccgaca agcgcaatcc gtactttttt cttcaagttc aagacacgtt cttctaattc
    11461 tttccattct gtcatgtctg cttctggtgt atctagtttt aaatggtcgc aaacaatttg
    11521 atccattcct tgtgcttgta aaactaatgg gatggagtaa agtgtatcta catctggcga
    11581 ctcgataact gcttctggtt cgacatcaca aaattgtgcc aatttgtttt tcacgctttg
    11641 agaaacaggt tgctctgtac gtaccaccaa aatattcggt tggataccta aaccacgtag
    11701 ctcttttaca ctgtgctgcg ttggtttagt tttcatttct ccagcagctt tcaagtaagg
    11761 aatcaatgtt gtatggatat acataacatt atctgtaccg acatctgctt tcatttgacg
    11821 aagtgcttca aggaatggca aagattctat atcccctact gttcccccta cttctgtaat
    11881 gatcacatct gaatcagtca ttttagctgc tcgcatgatt ttttctttga tctcatttgt
    11941 aatatgagga ataacttgaa cagttgctcc caagtattcg cccttacgtt ctttacgcaa
    12001 aacttcagaa tagatttttc ctgtcgtcac gttggagtat ttgttcaaat tgatgtcaat
    12061 aaaacgttcg tagtggccca gatccaaatc tgtttcagca ccatcatctg ttacgaatac
    12121 ttctccgtgc tgatatgggc tcatcgtccc cggatccacg ttgatgtatg gatcaaattt
    12181 ttggatagtt acttttaagc cgcggttttt caataagcgt cctaaagaag ctgcaacaat
    12241 cccttttccg attgatgaaa cgacaccgcc ggtcacaaaa atatattttg tcataagttc
    12301 aaaaactcct ttttaattta tgtgcaggaa aagtctcaga caataaacaa agctccctat
    12361 tcttcaataa gaatagggag ccgaaatttc tgtaaacttc tgaccctcta aaagggtgcc
    12421 caaggtgtat aatacaagct gactaaggga aagtcaagta ctcaaatgaa tactatccgc
    12481 ttacaatttt ttctttttcg atatcctttg agaaattatt tcttaagtcc tttatgagtg
    12541 caaaaaaaat ttaacccaca taataagctt gatataaaca tagctaacgt taaacctaag
    12601 caaatcagaa aatcgttact gaaaaatttt aagtgaaata ataga
//
LOCUS       DADVXK010000082        12612 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.083, whole genome shotgun sequence.
ACCESSION   DADVXK010000082 DADVXK010000000
VERSION     DADVXK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.083"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="KB909_002131"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="KB909_002131"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBB6838137.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="KB909_002132"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="KB909_002132"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBB6838138.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="KB909_002133"
     CDS             complement(2298..2960)
                     /locus_tag="KB909_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6838139.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="KB909_002134"
     CDS             3144..4790
                     /locus_tag="KB909_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6838140.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="KB909_002135"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="KB909_002135"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6838141.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="KB909_002136"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="KB909_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="KB909_002137"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="KB909_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="KB909_002138"
     CDS             complement(8939..10018)
                     /locus_tag="KB909_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6838142.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="KB909_002139"
     CDS             complement(10121..10561)
                     /locus_tag="KB909_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6838143.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="KB909_002140"
     CDS             complement(10618..11028)
                     /locus_tag="KB909_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6838144.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="KB909_002141"
     CDS             complement(11208..11642)
                     /locus_tag="KB909_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6838145.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="KB909_002142"
     CDS             complement(11742..12590)
                     /locus_tag="KB909_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6838146.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         4213 a         2348 c         2243 g         3808 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaattca tt
//
LOCUS       DADVXK010000083        12607 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.084, whole genome shotgun sequence.
ACCESSION   DADVXK010000083 DADVXK010000000
VERSION     DADVXK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.084"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(25..327)
                     /locus_tag="KB909_002143"
     CDS             complement(25..327)
                     /locus_tag="KB909_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6838147.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(352..2445)
                     /locus_tag="KB909_002144"
     CDS             complement(352..2445)
                     /locus_tag="KB909_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6838148.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2934..3698)
                     /locus_tag="KB909_002145"
     CDS             complement(2934..3698)
                     /locus_tag="KB909_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBB6838149.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3809..4678)
                     /gene="mdcB"
                     /locus_tag="KB909_002146"
     CDS             complement(3809..4678)
                     /gene="mdcB"
                     /locus_tag="KB909_002146"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBB6838150.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4703..5779)
                     /locus_tag="KB909_002147"
     CDS             complement(4703..5779)
                     /locus_tag="KB909_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBB6838151.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5803..6396)
                     /locus_tag="KB909_002148"
     CDS             complement(5803..6396)
                     /locus_tag="KB909_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBB6838152.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6400..8076)
                     /gene="mdcD"
                     /locus_tag="KB909_002149"
     CDS             complement(6400..8076)
                     /gene="mdcD"
                     /locus_tag="KB909_002149"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBB6838153.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8066..8365)
                     /locus_tag="KB909_002150"
     CDS             complement(8066..8365)
                     /locus_tag="KB909_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBB6838154.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8467..10118)
                     /gene="mdcA"
                     /locus_tag="KB909_002151"
                     /pseudo
     CDS             complement(8467..10118)
                     /gene="mdcA"
                     /locus_tag="KB909_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            complement(10125..11036)
                     /locus_tag="KB909_002152"
     CDS             complement(10125..11036)
                     /locus_tag="KB909_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6838155.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11156..12013
                     /locus_tag="KB909_002153"
     CDS             11156..12013
                     /locus_tag="KB909_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6838156.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12200..12562)
                     /locus_tag="KB909_002154"
     CDS             complement(12200..12562)
                     /locus_tag="KB909_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBB6838157.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
BASE COUNT         3548 a         2690 c         2201 g         4168 t
ORIGIN      
        1 ttttaccctc ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat
       61 tttttcttca atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg
      121 atcaactgcg aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg
      181 tttcatggaa actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt
      241 gttcaaaaca tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcaccgca
      301 tacgaataaa atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc
      361 aactactgaa aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc
      421 caacttctct tcgttgttga tcaattcaat tagttctttc atgatgttca gatgcgagta
      481 ggagtctact gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa
      541 atcgattggt tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg
      601 tcgggcatgg gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac
      661 tgcacgaatc atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct
      721 agcagctagt tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct
      781 gtccgtcaaa atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt
      841 tgtttcgaat aatttttcta acttgccata gatgattcga tctactcggc caccactttc
      901 tttcatgaca tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa
      961 ccgctgtagt tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt
     1021 taaaatcgga tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa
     1081 aaccagattg acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt
     1141 aatctcgatc tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat
     1201 cccatggtta cagacaacga ctgatttata aacataattc aagtctcgct tgattacact
     1261 ggcgatcgtc gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc
     1321 aattacttct tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt
     1381 tgttcggatg ttttctttca atggattcat gacttggata tgattcttga ttcttacaat
     1441 cagtgcagcc atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg
     1501 tacgtgtgtc tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac
     1561 ccactcgatt gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata
     1621 atttctttct acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa
     1681 tgcagaaaag ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc
     1741 atgtttcctg attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat
     1801 atcatcttct tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac
     1861 caaaggaaaa taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat
     1921 aaagaagtcg gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga
     1981 tcgttctgaa cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata
     2041 actgaccagt gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg
     2101 aaattcttct tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac
     2161 tagatcaaaa atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt
     2221 ttctaatcga gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt
     2281 acggatctcc ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg
     2341 gatcgtccgc tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg
     2401 ggctgtcatg attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt
     2461 ctgatttcaa gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa
     2521 gtggaaagaa agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa
     2581 cgaaaaagac atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg
     2641 tgaaaaagct gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt
     2701 tttcgtttgg ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagag
     2761 gttgtgacag agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca
     2821 tattttacaa aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga
     2881 aaaaggagct gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc
     2941 agcataatcg gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa
     3001 taccatatct gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct
     3061 tttcgatcga ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg
     3121 tggatctgtc gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca
     3181 ccgtctgctt tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa
     3241 cagcttctgg ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc
     3301 ttttggattt ccagaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat
     3361 atctccgctt tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc
     3421 cctcctactg acaaaacagc taatgcaaga aatcccgttt gctcataact agaaggacct
     3481 gtacctggac cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg
     3541 cccccatatg aacgaccacc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct
     3601 ccaccatgac cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc
     3661 actaacaaaa tgattgctaa ataattgatt tttttcattg tcttcctcgt tatcttttat
     3721 tacaaaaaac tatttttatg atagccttgc taaaaggaag agtcaataac cagatgcata
     3781 aactgttttt ttagcaattt tgtcttattt agtcattgag taacatcgga caaatgtatg
     3841 tgtcggcagt ccataattcc tctatcttca gcatgaacaa gcttgcagac aagagatctg
     3901 cgcttcctcc aggagagatt tggttttcct gacaaaagtg caacagtgct gtaaatggac
     3961 gatttggtaa agcactttga ctagcagcat gagcaagttt ttgcatttcc actaacgttt
     4021 tctgatcact gcgatgcaat acgcatgtgt catctagcga actcatcaaa actaacaaca
     4081 tatgcatttg tttctgtaca tatgaatcat tatctagctc cttagctgct tgaattgcaa
     4141 gcctgatatg cggataccct aatatcgctt cttcatatgc accatttacg ccatattttt
     4201 gcttcaccct atgaccatga gtggtttttt tatgacgata ttttgtatca ggaaaagcag
     4261 caagcttgct gacatcatca agtattttcg ataaagaaaa aggctgttcc atactgattt
     4321 tttgtgcaat gacactgatc aatagcccca ttgcccaaat cgctccttta tgggtattga
     4381 tgccatttgt agcaatcagc attgcctttt ccgcttttcg cccaatctca gcaattcttt
     4441 ctcttaactc ctgatcaata gcatgatgcc atgctatttg agccatttct tcaaaaaaag
     4501 gagttagcgt cttagcagac ttaagaaata aagcatagtc catatcggaa tgtgcacccg
     4561 catccagtgc atccactaat ccaggttttg gacttaatgt tacttctgcg atcaatgctt
     4621 cctctaccaa cgcagcgagt tgctgagtca ctgctttttt tcgttcgtca tttatcatga
     4681 cactcactcc ttcttcctac tattacttgc tgaaaccttt tttgatagct acccaaatga
     4741 tatgaagtaa ccagcttaaa gcaaatgcac aacttgccgt cattagataa gctacaagaa
     4801 tcatgactcc tgaaggtaac tgcagccaac tatctttaaa caataataac agtacttgga
     4861 aaacaaatac attggctaaa tacgtacgat aagcataaac agacaaccat ttgaacaatg
     4921 gcaattttgg cgaatcgttt acaatcattt tggaagcgcc tatgaagaca gcaaagatga
     4981 tgactaaact gtataaactt tggatcgtat tcaagtaagg tgcattcgca aagctcaagt
     5041 ctcctggatg tgcgagcaat gaacggacag aaaagaacgc gataactaag gcaacaggta
     5101 agaaaagata acgtactctg tccaaatatt gatagacttt ttcgtgataa acaaatgcgg
     5161 ctaccccata aatcatgaaa ctagcaacaa accgatctaa taagtaccag ctgtcatgat
     5221 aaggcccagt caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg
     5281 aaccaatcaa tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa
     5341 caaaaaacgg catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg
     5401 ctccatcacc tgtgacatat ttcagtaaaa agcttgcagt atccgtatac ggagtttgtt
     5461 gttggactgc tggaaatagc caaagataag ccgtcgtcca tagaagatac ggaacgacta
     5521 gttcaaaaaa cttttctttc aaaaattccc aataagacaa atgctgactt gtttttacca
     5581 tattataaac aattgcaaaa ataaacattg gtgctgtgta tttaacgatg acgtaaaagg
     5641 taccaagaaa agctgtattt gttgcgctgt ggctgtttgc caaagcaaag ctcaatatcg
     5701 tttgcatcat aacagccgtt acagctgata ctttctggaa gtcacttacg ttgattttga
     5761 tttttttgtt ttcaaacatc tctttctctc tctttttctt tattaccaaa gttctttggt
     5821 taatttaggt ccttcgactg ttttcaatag aatttttttc tctggctctc tcaaatactc
     5881 ttttagtgaa aaaccgcctt gccgagtcac tacttgggta tcgaattgct caaaaaaagc
     5941 aggatgcgat tgaattacct gaattggcaa ttcaatcggt gaatttgcgt acagcagcaa
     6001 atcaaaatca ctggtttctt ttactgccgg aatcccagtc gataattcaa atcctaagct
     6061 gccgccgatt ccccatttac atcctgataa tatgtttcta gcagcatgaa attgctgata
     6121 aacaggataa tccatgattt tctcttgtct atacgattct tgttcgatga tgtcccacgg
     6181 atgaatgact tgtttgacgg catgttttga gatttctgtt gaccatctct gattgcgggc
     6241 aggtccacgt aaaccaatcg gtagtatttc tgcgtgatcc gtcgacgcac gacgaactgt
     6301 tccgaacatc ttttcagtta gaacgaccca ttcaggcaag gtgaaccctt ctatttcatg
     6361 tttatcaaaa aggacaatat catgtgcttg aatcattttt tatgcatccc attcttcgtc
     6421 cattttggca cggactttat ttgtttcgac acgtccgaat gttttggctg tttcgtttgt
     6481 gtatcgattt gtcagcatcg tgtcatttgt attgcggaca tcttgaatgg cttcattgat
     6541 tgcttcgatg actttgctga cattttgttc tgaagcagct tggtcggtga tatcttctag
     6601 gaaatgatag atcgctccta gttttgtata attattgata tcgtaagcga tagctggaac
     6661 tttttcagca gctgcttcga tttcagcaac cgaacgtttt gtcacacgtg cagcactttc
     6721 tttagacatc gcttggacgg taatttcttt attgtttaaa gcaatcaagc ggcttgattg
     6781 taatccatgt gctaaaaatg cacctgaaat agcatttcct gcaatcaatc caataactgg
     6841 atgtccagct tgacggagtt ttgcataagc agcagcacta ttagccaaag ccacatggat
     6901 accgatcaat tcttcgttat agccgtatgc ttggcttggt acatcgatca caacgatgat
     6961 tggccgtttc acttttttgt ctttatcttc ttcgtaaacg tgatccaaaa tttgtcccat
     7021 gcggaaacct tcaactaaac caacttcacc gtttcgtaca cggtacatcg ggtttttagg
     7081 atcaggtacg attgatgtca cgatggcttc ttctatgaat ttacttgatt taccataata
     7141 cacagtacta atagaagaag ttggattttt catgccagtt agtgccgcaa accaatcgta
     7201 accaacactt gctgcagctg gttcatttcc ttctgctact tctggtaagt caattgattt
     7261 tgcttgatgg ttagcaattg cttcattgta atcgtcaatg gccattggtt ttgaaagatc
     7321 taaagaatca agtaatgata aataaaatgc tgagctttca ctgcgatgcg tgtcttttcg
     7381 ttcgtccatt gctgcgatga cagcagcttt gattgcttct acactatcag tcactaattc
     7441 atcaatgatt tttgattcta cccgttgacg agatcctaat gtattccaaa tcaagtcttt
     7501 gtcactagaa tcaaattctc gaacgcctgc ttcttgttca ataacttctg gtccattcaa
     7561 accgactctc gctttttttg ttgcgattaa ataactcatt aatgctgaag taatcgacat
     7621 accgccaaat gatcctacac gtcctggaat caaaccgatg actggtacat attgttttag
     7681 agcaatgatt acatttccga tttctgaaat agataacagt ccgtagtttg cttcttgcaa
     7741 acgaacacca cctgtatcta gtacaatgac tggaaagatc tcatttcctt ttttattttc
     7801 ttctaacaca tgttcaagtg cagcaacgat ttttgcaccg gaaacttcac cgataccgcc
     7861 accttggaat tttccttcca tagcgattac tactgcttgt ttgccattga tcgtgccacg
     7921 gctgacaacg atcccgtcat cactttcagg gacgattcct tgtgctggta aacttggcgc
     7981 gatgatttga tcgaatggat caatcaattc acgtccattg tcaagtagag cgttcactcg
     8041 ttctctggcg tttaattcta caaaactatt tttcatctga aagttcctcc attgcttgcg
     8101 tcaatcgtag gtacacaact cctggtgtag caccgaagtc attgatcacg atatctgctg
     8161 aaattggata acgatcaaaa aatctcgtta atacattgtt ccatacttcg ccgaagccat
     8221 cgcttcctgt acaaattttt acagtagatt ctgttttttc tgttggaaac atcaagattt
     8281 ccaaatctcc tgaaccgacc actcctacat ggattttctt attgatcggc tgtttcgttg
     8341 gatatttata agctaattgt tccatggatc tctccccttt ttgtaaaaca gagcatacac
     8401 gttctgctta ttcgtctttc ttcttccatc tgggtaaatg gcgacaaaag gtttttctcg
     8461 ccaattttat gaccaagttc tgaatttcat tggtggttca tacaggccat ctgaccattc
     8521 gatcaaatca tcgatggttt gtgcagctaa taatgaacgt ttcgcttcac tacgtttgat
     8581 gcctagatct tctggtaatt tcacgatgcc ggctgcacgc aagctatcta gtgattcttt
     8641 cgtgctagtc attccaagag gtgtaacacc gccaattgct gcaattgctg cttgtcgttc
     8701 ttcttttgtt tttgctttgt acaaataagc aattccttct tctgtcacga tatgtgtagt
     8761 atcttcgcta taaatcatca ctggtgcatt gcattggcta agcctgcttg tttttgaaca
     8821 gctagtgcat ctaattcttc gacaaagact ggttttttat ttgaaccata tgtttcaacc
     8881 atttgaacaa ctaatttttg gcctttccct aatggatcat cattgtcgcg aagtgattgc
     8941 catgctggtg tagaatgacg acgaccgcca ggattatgtc ccatgttagg cgcaccgcca
     9001 aaaccagata aacgtccttt tgttacggta gaagagtttc cttcgtaatc taattgcaag
     9061 gttgaaccga taaacatatc gatggcatat tgtcctgcag cttgtgataa tgttcggtta
     9121 ctgcgcatcg tgccgtcttt accgacaaaa aagacatctg ggcgagcagc aatatatttt
     9181 tccataccaa cttcgccacc aaaactatgg atgctttcaa cccaacctga ttcgatggct
     9241 ggaatcatcg ttggatgtgg gttcaatacc cagttcttcg cgattttccc ttttaaccct
     9301 agtgattcac cataagttgg cagtaacaat tcgatagctg ctgtattgaa tccaataccg
     9361 tgattcaaag attgtacgcc gtgttctgcg tagattcctt tgattgccat cattgccatt
     9421 agaatttgca attctgtgat gttttgagga tctcgtgtga ataaagcttc taattgataa
     9481 ggtttatctg ctttcacgac aacgtctacc cagtcaccag ggatatctac acgtggtaaa
     9541 gaatcgacaa cttcgttaac ttgaacgatc acgataccat ctttgaaagc tgcagcttcg
     9601 atgattgttg gtgtttcttc cgtattgaaa cctgtgtaca agttgccgtc tttatctgct
     9661 ttatctgcag ctactaaaac aacatttgga atcaaatcga tgaataagcg tccataaagt
     9721 tccaaataag tatggatatc acctaatttc attgtgccgt cttcaatcat ttgggcgaca
     9781 cgcaagcttt gtgcaccagc ataagagaaa tcgatcttgc ttgcgattcc tttttcaaaa
     9841 atattcaaat gttctggtcg tgagatacta gacatgatca aatgcagatc attcactttt
     9901 tctgcatcta ctttttcaag actttctgaa agaaaacttg cttgtttttg attgtcgcct
     9961 tctaatacaa ctttgtcgcc gggagcaatc agtttttcca ttacttctac gattttttca
    10021 gtttctacat acttgccatt gagcaagttg ctgatttttt ccaatcgctg cgcttttttt
    10081 tcgcgtttag aagcccagtt gcggtttggt ttttccataa ttagtcatct ccatttttga
    10141 tatagaaacg tggcgtcatc aataccatgt tggtctagat tgatcgtacg gatcccttta
    10201 tctacaccaa attttgtatg aatcagcttt gtcaaagtat tgccgggggg aaattcaatc
    10261 gtcagatcca ttcctaattc ttttgccaag tccatcattt ggttccactg cacagggaaa
    10321 gctaggtttt ccaacaaatc tttacgaatc tcttctgcgt cctgagtggc tcttccatcc
    10381 gtatttttta tatacaaaca tctagcatca gatagatgga cagactgcat atacggcttg
    10441 aatttcttga ccgtatcatt catcaagaga cagtgagatg gcacagggac tttcagcagc
    10501 ttcgctgttt gcgcttggtg ccgtttggct tctgccaacg taacggataa accttcgata
    10561 ctcccagata acgtatgttg catcggacaa ttttcatttg acagataaac tggatggtca
    10621 ggatcaaatg tttttgctac aatttcctca gcttcgcttc tcgtcacacc tactactacg
    10681 cccattgcat aaccgcttgg ataagcttct ttcattaaga ctgcgcggtg atagactagt
    10741 tccgctgcat tctcaaatct caaagatcga caagcaacag ctgcacaaaa agcaccaatc
    10801 gaatgtcctg ctgcaatatc aggctgaata ccgttttttt ccatttcatc taaataaaat
    10861 actgcttttg tcagtaatgc tagctggata aaaaccgtat cttgatagtt ttcttcttta
    10921 tcaactaacc gataccccgt cacattttct aaacgttcca tgtacatttc agggatatcc
    10981 gctaacatcc ctaacttctg actgccttgt ccaggaaata agaaacctgt actcatgagc
    11041 ctcgcctcct cagcacttac tttttccact gctatcttag tcaatttctg ctataataaa
    11101 aaatgccaaa aaaagaaaaa accataacaa aaaggtatgg atgggatgga taattatgaa
    11161 attgcttcat ctgcagtatt ttaaaaaagt attcgaaaca aaaaatgtta cccaagcagc
    11221 caaagaatta tttatttctc aacctgcctt gagccgtgcg atcaaacatt tggaaaacga
    11281 attaggtgtc cctttgtttt accatagcgg cagaaacatt gagacgaccg tttatgcaga
    11341 agaattttat ccatatgcag tcaagacatt agacacatta gaagaaggaa tcaaattatt
    11401 gtcttcggtc aatgagaaga tcgttacttc cgtcatattg tatttagagg tagcctctgt
    11461 ttctattccg aacttggtcc gaatttttat ggaaaagcat cctgatatcc aattaacgat
    11521 catgcaacat catttaccag atgatattac cgatcctgta ctgtacatca cttcggagat
    11581 gaagcctggc atgaccaata ttcctatcat gaaagaacct gtttatgtcg ccattcctaa
    11641 gaaacatcct cttgctaaaa aagaacatct gcaattagaa gatatccaac gcacccccat
    11701 cttgatgctg tcaaagagca acgccttccg tcatacactg gatgcagcac ttgaagcgaa
    11761 aagtatcgaa ttgacgatca gttcgacgac agatgatcct gcgacattac gttctattgt
    11821 caagcaagga ttagctgtta gctttttccc aaaagtttct tggtcttacg ataaaaatga
    11881 tcctttcgtc ttgcgggaaa tcaaagattt gcccttgaca cgaacaattt atttatcttc
    11941 tagcttcaca gaagatcatc ctttgatcaa aatgattgca aaaacgatgc gggaatttta
    12001 tttaggaaaa taaaaaaaaa agagctggga caaaattctt gtcgcagctc ttttttcgaa
    12061 caaacggtgt tccagaagta atttcttaga aaataagccg aaatttccca aaaatttgag
    12121 aagcaatttt cgtaaattcc ttcttatttc ttgaagctaa acatttctgt cacaacctct
    12181 tctctattgt cctagacatt cattgcgttg atttaaaact tccatcaatc aaatctgcta
    12241 gttcatctag cttttctatt ttacgtagat caatagagat ccaatgttct ttattcatgt
    12301 gataggctgg aaaatacccc tcttttcctc gcaaaattcc gccaagttca ggatcgacct
    12361 tcaaatcaag aatattgatg atcctatggt cacttgcatc atcatagatt ttttcttctg
    12421 gaacagacat caggacccca aaccattttt tgcttttttg atgtctgaat acgcaataat
    12481 caggaaattt tttaaaaata tattctggag acaaattgta tgtttcattg atgtgatcga
    12541 ttagttcttt tttcgttagc atctgcttcc atctctttct tattgattcg ctttattcaa
    12601 agatacc
//
LOCUS       DADVXK010000084        11888 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.085, whole genome shotgun sequence.
ACCESSION   DADVXK010000084 DADVXK010000000
VERSION     DADVXK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.085"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            27..2045
                     /locus_tag="KB909_002155"
     CDS             27..2045
                     /locus_tag="KB909_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6838158.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    2115..2321
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2472..4886
                     /locus_tag="KB909_002156"
     CDS             2472..4886
                     /locus_tag="KB909_002156"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBB6838159.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            5234..6787
                     /locus_tag="KB909_002157"
     CDS             5234..6787
                     /locus_tag="KB909_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6838160.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(7168..8952)
                     /locus_tag="KB909_002158"
     CDS             complement(7168..8952)
                     /locus_tag="KB909_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838161.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(8967..10688)
                     /locus_tag="KB909_002159"
     CDS             complement(8967..10688)
                     /locus_tag="KB909_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838162.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            10788..11549
                     /locus_tag="KB909_002160"
     CDS             10788..11549
                     /locus_tag="KB909_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6838163.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         3887 a         2155 c         2419 g         3427 t
ORIGIN      
        1 gataaattga agttggagga tagaagatgg aaaacattgc aagaaaagaa cggagacgtt
       61 tagaacagac caaacgtttt cgaaaagcaa aacgaggggc agcaatcgtg ggaactgcga
      121 tggtaggctg ttctgtcgct gccccattag tacagccggt tcctgttcaa gcggatgaaa
      181 cacctgttca gttcggcgca agaatcaata cagcggcatt tatcacagaa attgctactt
      241 atgctcaacc aatcgctcaa gccaacgatc tatatgcatc agtgatgatc gcacaagcag
      301 ttgtagaaag cggttggggc agtagtgcgt tatctcaagc accttattat aatctttttg
      361 ggataaaagg cagctatcaa ggacaaaccg tctacatgga tacgcttgaa tttttaaata
      421 atcaatgggt aaataaaaag gagcctttcc gacaatatcc ttcttttgct gaatctttca
      481 atgacaatgc ctatgtactt agaaatactt catttggcaa cggttattac tatgccggta
      541 cttggaagag caacacgaaa tcctatacag atgcgacagc ttgtttgaca gggcgttatg
      601 cgactgatcc tggttacgca ggcaaattaa ataatatcat cgcaacttac ggattgaccc
      661 aatatgatac accagctagc ggaaacgcag gcggtggagc gactacaggt ggcaataata
      721 ctggaagtgc aggtagtact ggcggttcaa gcaattctgg taatacaaac tcaggttcag
      781 caacttcgac cacttatact gtccaatctg gtgattctgt ttggggaatc tcaaataaat
      841 tcggtatcac aatggatcaa ttgatccaat ggaacaacat ccaaaacaat ttcatttatc
      901 caggacaaaa actgacaatc aaaggtagcc aggaaaatgg ctcttcgacg aataattccg
      961 gtaacaatac caattcttca ggaaatgctg gtacatcaaa cggaggacaa acaactggtg
     1021 cgaaatacac tgttcaatct ggtgattctg tttggaagat ctcaaatgat cacggaatta
     1081 cgatggctca attgattgaa tggaacaata tcaagaacaa tttcgtttat ccaggacaac
     1141 agctaatcgt atcaaatggc ggttcttcta atgctggagc aaatactggc tcaaatactg
     1201 ggaatacaag tggctctagt tcgtccagct caagttcttc taatacagct tcaggaacga
     1261 aatatacagt taaagccgga gactctgttt ggagcgtctc aaataaatac ggaattacga
     1321 tggctcagct aatccaatgg aacaatatcc aaaataactt tatctaccca ggacaacaac
     1381 tgactgtttc aaacagtgga tcaacaaaca gcacgtcagg taatacaggt tcgtcaacca
     1441 atacaaataa cagcagttca gttaatactg gcagcagttc gtctcaaggc acttataccg
     1501 tgaaagcagg tgaatctgtt tggagcgtgg caaataaaaa cggcatcacg atggatcagt
     1561 taatcgaatg gaataatatc aaaaacaact tcatttatcc aggacagcaa ttgatcgtta
     1621 aaggtggaac ttcggcaaat acaaatacag gttcaactac ttctgcagcg aaaccaaata
     1681 caccgaatac gtctgctacg acaagtacat catccactgg taatacgatg tataccgtga
     1741 aagcgggcga gtcagtttgg agcgtagcga acaaacatca tatcacgatg gatcagttaa
     1801 tcgaatggaa taatatcaaa aataatttca tctatccagg acagcaagtg attgtgaaga
     1861 aaggttcatc tcaatcaaca aaccaacaat cagttactgg ttcgaaaacc tatactgtga
     1921 aatctggaga atctgtttgg agtgttgctg acagtcatgg aattacaatg gctcaactaa
     1981 tcgaatggaa caatattaag aacaacttta tttatccagg tcaaacgttg attgtagcta
     2041 aataaaatag ctgttcgaag aaataacgat tgaattccac aaaaatattt gttactataa
     2101 ggctacttaa atatgacaac acttgaaaag gaagtagtaa aaagactgaa gtttcagaga
     2161 gcgcatggct ggtgagaatg tgcacggatg cttttgaact cgcctttgag ttgcccttgc
     2221 tgaatacccg agtaagcaag cggcggtgac ggccgttaca acgttcgagg ccttttcact
     2281 aaggtaaaat taggtggtac cgcgtagatt acgtcctata aaaagagcaa tctttttata
     2341 ggattttttt atttcttttg tgaagtttga gaaaacaaag caaaaggaaa taaaaataaa
     2401 cagattctgc cggttttttc gttatattta taatagaaac aagtgttttc aatagaacag
     2461 gaggacagca aatgagttac aatcataaag aaattgagaa aaaatggcaa aaatactggg
     2521 caaaaacgaa tactttcaac acccatgatg atcctgaaaa gccaaaattt tacgcactgg
     2581 atatgtttcc ctatccatcc ggtcaagggc tacatgtagg gcatcctgaa ggttatacgg
     2641 caacggatat cctttcacgt gtgaaaagaa gtcaaggata caacgtgctg catccaatgg
     2701 ggtgggatgc attcggtctg cctgctgaac aatatgcgct agatacagga aacgatccag
     2761 ctgagtttac ccaaaaaaat atcgaaacat tccgacgcca aatcaattct ttaggattta
     2821 gttatgactg gaatcgcgaa gtgaatacaa ctgatccgga gtattataaa tggacacaat
     2881 ggatctttac gaagctttat gaaaaaggtc tagcttatga agcagaagta gcggtaaact
     2941 gggtacctga attaggaaca gttatttcaa atgaagaagt gatcgatggg aaaagtgaac
     3001 gtggtggcta tgatgtagtc agaaaaccaa tgcgccaatg gatgctgaaa atcactgctt
     3061 atgctgatcg cttattggat gatctagaat tagttgattg gccagaaagc attaaagaaa
     3121 tgcaaagaaa ttggatcggt cgttcagtag gagcaaatat tgaatttaaa gtggctggta
     3181 cggataaatc ctataccgta tttacgacac gaccagatac tctattcggt gcaacttact
     3241 cggttcttgc acctgaacta gatcttgtta gagaaattac gacccctgaa caaaaagctg
     3301 ctgtagaagc ttatatcgaa gagacagcta aaaaatcaga tctaaagaga acggatcttg
     3361 caaaagaaaa aacaggagta tttactggtg cttatgcaat caatccagtt aatggcaagg
     3421 aaatcccaat ctggatcgcc gattatgtat tatcttcata cggcacagga gccatcatgg
     3481 ctgttccagc acatgatgaa cgtgactttg aattcgctca aactttcgga ctagaaattc
     3541 ttccagttat cgaaggtgga gatgttgaaa aagctgctta cacagaagat ggtacgcaca
     3601 tcaactctga atttctagac ggcatgaaca aacaagaagc aatcgataaa atgaatgaat
     3661 ggctagaaga aaatggcgta gggaaaaaag aagtcagcta tcgcttacgt gactggctat
     3721 tctcccgtca acgttactgg ggtgaaccaa tcccaatcat ccattgggag gacggaacag
     3781 tcacagctgt cccagaagaa gagctaccat tacggttgcc taagacaaaa aacatcaagc
     3841 caagcggtac tggagaatct ccattagcaa atatcgagga gtgggtcaat gtcgttgatc
     3901 ctgtaacagg taaaaaaggc cgtcgcgaaa cgaatacaat gccacaatgg gcaggaagct
     3961 catggtatta cctgcgttat atcgaccctc ataacaaaaa agaactagca gattatgaaa
     4021 agttgaagcg ttggctacca gttgacatct acattggtgg agcagaacat gcggtacttc
     4081 atttactata tgcacgattc tggcataaat tcttatacga tatcggtgtt gttcctacaa
     4141 aagaaccatt ccaaaaacta tacaatcaag gaatgatctt aggcgaaaac aacgaaaaaa
     4201 tgtcaaaatc tcgtggtaat gtagtcaatc ctgatgatgt ggtcgaaact tacggtgcag
     4261 atacactgcg catgtacgaa atgttcatgg ggccattaga tgcttcgatt gcttggagcg
     4321 aaaatggctt agaaggaagc cgtaaattct tggatcgtgt atggcgtttg atcgttgatg
     4381 agaacaataa aatgcgtgac cgtatcacta cattgaatga tggcaagctt gataaagtgt
     4441 atcatcaaac agtgaaaaaa gtgacagaag actatgaaaa tcttcatttc aatacagcaa
     4501 tctcccaatt gatggtcttt atcaatgaag cctataaagt ggacgctctg ccttatgaat
     4561 atatcgaagg atttgttcaa ctactcgcac cgattgctcc tcacatgggt gaagaactat
     4621 gggcaatcct tggaaatgat ggtggtattt cttacgcacc atggccaaca tacgatgaag
     4681 cagcacttgt tgaagacgaa gtagaagttg ttttccaagt aaacggtaaa gttcgtgcga
     4741 aaagcaatgt tccccgagac ttaggaaaag atgagctaga aaaagcagca ttagccaatg
     4801 aaatagtgca agaatatatt gaaggcaaaa cagtcagaaa agttattgcg gtaccaaaca
     4861 agttagtcaa tatcgttgct aattaattgg ctctttgtca ataaggactg atgagttgtg
     4921 caaaatcaaa tctgggccag aatgaacttc attctgtctc agattttttg ttatttcaaa
     4981 ttgattaatt gattgatcaa aaaggttttg attttcatgt tctcaaacac gttcaatgtc
     5041 tttttcttct gaatggtctt gtaagagatc tctgtaatca tcaaattttt gtctattaat
     5101 cttagtattt tttgatgtat aaactacctg aaattgagag tacataccaa attcataaat
     5161 tttttattag tgggactagt gattgtatgg attttgacgc ataatgaatg aagtatgaga
     5221 aaaggagaga caaatggatc aagaactatt tattatcgaa gtattatcag ctaaacaaaa
     5281 aattatcgag aaagcgaaaa aaagagcgaa aagaataatg ttcaagcttt taagcttagt
     5341 atttttctct ggtttgcttt ttttcggagc tgtatcgttc ctatatcgcc atatgagtgc
     5401 agtagtccgt tcagctgaag ggatgcaaaa attaaataat ttgtatcact tttcgtgggg
     5461 agttggcgga ataacaattg ttgtgcttat tgtttttctt ctacttattt ggctccgtta
     5521 ccatcaattg tcgcgtcatt tcgatcaatg gcttagtcaa agagcacaac agtttttaca
     5581 taataaacca acttctcaag atgatgacta tctttatttt gagaagactt cgacgagtca
     5641 agcttttcgg atacaaaaaa gtgattgcca gttattgctg agatcacttg atgatttacc
     5701 tatctactta ggcgaaagca aatcaaaatt cggaatgaac acattccata tttttttact
     5761 agaaaacgaa cccagatggg aaaaaagcca gtcttcgcct ggtggatacc tgacaactaa
     5821 gatgagtaca ttagtcactg gttttttcct cattctttta gctggaacaa tctattatgg
     5881 gagatacact cagccaaaaa tgtcttctca tataaatgct gcttctcaca tgacaatgaa
     5941 ctcaactaac gatacgcata tacaaaagac aaatgaaggg ttgttagctg atcctaagca
     6001 aaaggtaaat ttgacaacac aaaagataaa tgatctcaaa cttgatacag agacgcactc
     6061 tctctatatg acaacagata gtggtgctaa ttgggtattt gtgccgattg attcgcaatg
     6121 gttgcgtttt ggcgaataca ccctgacaac ggggctgatt cctgaaggtt attggatgga
     6181 caacacatat gatatttccg ccgatttctc atggtttatc tattcttctg gggatgatgt
     6241 acgtctgctg acttcaagag ataatggtaa aacatggcaa acgtctatta tcacccaatc
     6301 agttcagccg atacgttatc gaaaagcggt attttatggc aacgatggtc tatttatctg
     6361 tacatcagcc agtgggatgt ctgcagaaac tttgtacatt tacactacta tggatggcgg
     6421 aatcacttgg ataaaaagtg gaagtacaat gatcaatcag ccagtacaaa atgtcagctt
     6481 cgttacaact tctttaggtt ttgtttcgac acgtgaaagt ttgttttata caaacaacgg
     6541 aggacgctca ttcaaagaat cagttctgtc gattccggaa aactatcaga caggggggat
     6601 agatcttttt caatcaccaa atgaagttac tcaaataagc gcgaatacgt tagagacaaa
     6661 attttatttg ttgaaaaaag gaccaatcga tgcagggaaa atgtttgcct gcctcttccg
     6721 ttcaactgat aacggggaaa catggcaatt cgttcagcaa ctatcgcaag tagaacaagg
     6781 agattaaaga agagagattg tgagcctgac gttcagcacc gagtcacaag aaacaaattc
     6841 aaaaaacagc ttctcatatt tgttgaatag tgtaactcgt gattcggagt tgacaagagc
     6901 aacaagaagc gattttgaag tatagcttct cgtattttac aagatcgtgt cttattgccg
     6961 ataggttgtc tcttgaacac cgtttattcg taaaaaggga ttgtgacaag tcttttgtca
     7021 ctacttaccg aacgaaactg aaggagctat ccaaaaagta tcattagtat tattctttgt
     7081 gtttctagtg gcaccactag tacatttaaa aaagctatcg atcatggact aatcatacat
     7141 gatcgatagc tttttagata atgtttgtta cgctatctga aattgactat tataaagact
     7201 ggcataaagc gttggtgatt ggagtagttc agaatgtgtt cctttttcga cgatatcgcc
     7261 attcttcatt acaaggatca tgtctgcatt ttcaatcgtt gacaaacggt gtgcaatcac
     7321 aaaacttgtc ctatcttttg tcacagcttc cattgcttgc tgaatcaatg cttctgttcg
     7381 tgtatctacg ctagaagttg cttcatctaa aataacgaca ggaggattcg ctagaatgac
     7441 tcgagcaatt gtcaataatt gttgctgtcc ttgagataac gtgccgtttt cgctagaaat
     7501 gatcgtatca tatccgtctg gcagtgttcg aataaagtga tcacattgtg cgatttcagc
     7561 cgcttcgata atttgttctc ttgtggcatc cattttcccg taggcgatat tatcagctac
     7621 cgttccttca aacagccagg tattttgtaa aaccatccca aaagaacgac gtagttctcc
     7681 acgtgaaagc ttggtaatat caagaccgtc gaattcgatc tttcctttat tcagttcata
     7741 aaaacgcatc agcagattga ctaaagtcgt ttttcctgca ccagttggac caacgatcgc
     7801 taccgtttgt tttggcttta ctgaaaaatc gacttgattc atcaatattt tatctgatgt
     7861 gtaaccaaac tgtacatttt tgaaagctat ttttcctttc ggttgttcta aaagtcttgc
     7921 atctggaagg tctggaattt catctgtttc atctaatatc tcaaatatcc tatcgattgc
     7981 tgccattgcg gattggatcg agttgatcac ataagaagcg gtagaaattg gttcagaaat
     8041 ctgattgatg tactgaagat aagcttgtaa gaagccgatc gtcacaccac ctgatagaac
     8101 aagcatagca ccgaataccg cacttatgat gaaggcgagt tgattaatga aacgaatggc
     8161 cggatagata gcacagttca taaattgagc acgtttaaaa gcgttgtatt gctttttatt
     8221 tacttcgtgt atagcagctt ctgcatgagc ttgctgattg aatgttttga ccactagatt
     8281 accagctaag atttcttcca ttcgattatt taaaacaccc agttcatact gattctgttc
     8341 agaaatctgt ttgtttttgt tcgcaatctt agttgtaaca attgaactgc caacgatcag
     8401 caataagacg agcaaagtaa gcttgctttc gatataaaac agcatcagac cagcagcagc
     8461 tattgttacg acagaagtaa aaaattgatt gatacctgtc aataacactt gagaaagttg
     8521 attgagaccg gtagttgtcc gactaatgat gtcacctact tgatgattgt caaaaaacga
     8581 catcggtaat gttttgaatt tttttgtgat ttcttttcgc accctcaatg tgatcttttc
     8641 gcttaacgct gccattgtcc gttcctgaat aaatgaagtg atgctgctta agactgaaca
     8701 gccgatcagc aataagacag ggaacaacaa tgcttgtttg atatcactga aagaaagctg
     8761 tccaatacct gtttttctta tttctgataa gagatcatcg atcccgattc ccatgatcaa
     8821 gggcatggct acgactaata ggttcccgaa taaactgcat agaaacaatc cgtaaaaata
     8881 tttatgttca ggtttgatca ttttccaaaa acgtatcaaa gcacgcgtgt tcaacgtttt
     8941 tttcttttcc atcgtatccc ttctttctat attccttgtg attttgcaaa ctcctgataa
     9001 gtttggcaat tagacagtag ttcttcatga gtaccttgtc caacgatttt tccttcatct
     9061 aaaacaatga tgttatctgc ttgttggatt gtactgaggc gttgagcaac aatcacgaga
     9121 gttttctccg acatgtgttt atgaagggct gctcttaatg ctgcatctgt tttatagtct
     9181 aaagcggaga aactatcatc gaatacatag atctctgctg gtttgatcaa cgctcgagca
     9241 atacatatcc gctgtttctg gccccctgaa taattagaac cgccttgagc aacaaagctg
     9301 tccaatccgt caggaagggt gtccactagt tcttctaatt gagcgatctt gatcgcttta
     9361 gacaactctt ctgttgaggc atattcattt cccatctgca agttgcttaa aattgtcccg
     9421 ctgaataaga aagccttctg agggacataa ctgatgtggg agcggatctg ttcttgagtc
     9481 atttgagtaa gaggaatacc accaagggtt acttttccta tcgtagggtc actaagtctc
     9541 aagagaagtt tcgccaaact actttttcca gatccggtcc cgccaacgat cgctgttgtt
     9601 tttcctttag gtattgtgaa atcaatatct tctagaactg gatcagagat ttcagtatat
     9661 ttaaatgtga catgttcaaa agcagctgca tttgtctgat caaaggttgg ttcagctact
     9721 gttttgatcg tctcttcctc aatttcgatc tctgcttgca gtatttcttc tatccgtcgt
     9781 aatgaggcaa acgatttagg gataatgacc aataccatag ctgcgatcat caagtaagca
     9841 agtgtcagca tagagtattc gactacagca gtcacgacac cgatttgtaa tgctccttct
     9901 gctacaagat ttccgccaaa ccacaaaata gaagcataaa cgattcccat gagcaaaaaa
     9961 gcaattggag tgacccaagc aaatattcgg ttcactttga tcatttgatt agcatagtca
    10021 gcaaagctct tattcgttcg cttttcttca tatgattgat tatcaaaggc acggatcata
    10081 ttaatcccag taaagaattc tctcaatgtg atggtgatcc gatccatttt tggctggata
    10141 ctcaaagata aaggtgcccc tcgtttcatc agtcgataaa caatccatac ataaaaaaca
    10201 acagagatca atgtaaccca tgttagtaat agagaataac gaaacatcat gagaatggtg
    10261 aaaacgcaaa taaccggtgc tggtaagatc atttggcaaa ataaaacaat catttgctgg
    10321 acattatcga catcattcgt cattcttgtc aaaagagatc cagaactaaa acgactgata
    10381 tccttcattg acagctgttg gaatttacgg aaatatttct cccgcgtttg gaatccaaac
    10441 ctagcggaag ccaatgctga aaagtaacta gaggcaactg cagcgattgt tcctagaaac
    10501 gctacaagca gcatttcaac tccaattttt tttataactg aggcttcgcc acttgctata
    10561 cctgtgtcga tcagctttgc tactaatttt ggtacaccta atgtaccggc gatttctaaa
    10621 cagatcatca caaaggtaag gagagcgagt cctttgtttt tctgtaagaa tgtttttaag
    10681 atagacatat tattcctcct tttttcctga tacttttcga ttctatacct tcaagtaact
    10741 tgaaggtcaa tagaaaaaag aataaactga aaaagaggtg agaaaaaatg aaaaaaatgt
    10801 atacgattgg ccaagtatcg gaactatttg atttgccaaa atcaacgatc cgctattggg
    10861 atgaacaagg attaatccgt tcaagtagac aagaagagaa tgattatcga ttgtttgata
    10921 tcgatgatat ttttatgctt tatgatatcg ttttttatag aaaattagat ataccgatca
    10981 aacagatgaa gaatttatat ggaaaaacat tgacggagtt atatgagaca cttgatgaaa
    11041 cagaaagaag aatccataaa gaactggtgg tgatgaaaca aaaacaaaaa gagataaggg
    11101 agcaaaaaaa acagttgaaa ttgatgatcg atacaaacga ggaagaattt cctgtagaag
    11161 agatcccttt tgactgtatg atctcaacgg agtttgaaga tattgtggaa atcaaaaaat
    11221 ttctacctaa ctattcaagc tttgggatga tgagtatgcc agcttccagt tcacagacga
    11281 tgtatggatt ttttatcgac cctagtgaag tacatttatt tactcaagac gtgatttggg
    11341 agaaaaaaga tacggctgtt tatcgtcgat tcttattgaa atccgagatg aaccatgcgg
    11401 aacgtaataa tattttagaa atcagagaaa gaatgtatga aaaaggatgg aaaacaggag
    11461 aagtgatcgg ccagtatcta ttgacgaata cggatgaaaa caatatcaga actgaatatt
    11521 atcatgcatg gatagaaatg aaaaaatagg aaatatgtgt ttaagataac tcgaaaatga
    11581 tggttgtttt agttataaag aaaaattttc tggttcgatt acgggtttaa tgtgggggat
    11641 tattagtcgt ggatagatag aattttagtt ttttagagga aatatgtctt taaaaatgga
    11701 atggttgcaa ttcttagcga tatatacgat gtaattgtcc tcttaaaaaa gtatggaaaa
    11761 ataattgtat tgggtgttat gtataattca tggtgaactg agactaatga gaagaaaaat
    11821 tcatattgtt atgagtgaga ttgtatcaga tgagaatgat aaattaaata ggtgcataaa
    11881 agcattac
//
LOCUS       DADVXK010000085        11779 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.086, whole genome shotgun sequence.
ACCESSION   DADVXK010000085 DADVXK010000000
VERSION     DADVXK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.086"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            506..1069
                     /locus_tag="KB909_002161"
     CDS             506..1069
                     /locus_tag="KB909_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838164.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1130..1495)
                     /locus_tag="KB909_002162"
     CDS             complement(1130..1495)
                     /locus_tag="KB909_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838165.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1571..1816)
                     /locus_tag="KB909_002163"
     CDS             complement(1571..1816)
                     /locus_tag="KB909_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838166.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1886..2140)
                     /locus_tag="KB909_002164"
     CDS             complement(1886..2140)
                     /locus_tag="KB909_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838167.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2304..2627)
                     /locus_tag="KB909_002165"
     CDS             complement(2304..2627)
                     /locus_tag="KB909_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838168.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2814..2887
                     /locus_tag="KB909_002166"
     tRNA            2814..2887
                     /locus_tag="KB909_002166"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2848..2850,aa:Ile,seq:cat)
     gene            complement(3272..3769)
                     /locus_tag="KB909_002167"
     CDS             complement(3272..3769)
                     /locus_tag="KB909_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6838169.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3809..4618)
                     /locus_tag="KB909_002168"
     CDS             complement(3809..4618)
                     /locus_tag="KB909_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6838170.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4952..5809
                     /locus_tag="KB909_002169"
     CDS             4952..5809
                     /locus_tag="KB909_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6838171.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5802..6704
                     /locus_tag="KB909_002170"
     CDS             5802..6704
                     /locus_tag="KB909_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6838172.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6737..7087
                     /locus_tag="KB909_002171"
     CDS             6737..7087
                     /locus_tag="KB909_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6838173.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7136..8059
                     /locus_tag="KB909_002172"
     CDS             7136..8059
                     /locus_tag="KB909_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6838174.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8137..9030
                     /locus_tag="KB909_002173"
     CDS             8137..9030
                     /locus_tag="KB909_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6838175.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9068..9631
                     /gene="amaP"
                     /locus_tag="KB909_002174"
     CDS             9068..9631
                     /gene="amaP"
                     /locus_tag="KB909_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6838176.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9645..9833
                     /locus_tag="KB909_002175"
     CDS             9645..9833
                     /locus_tag="KB909_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6838177.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9846..10748
                     /locus_tag="KB909_002176"
     CDS             9846..10748
                     /locus_tag="KB909_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6838178.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10780..11022
                     /locus_tag="KB909_002177"
     CDS             10780..11022
                     /locus_tag="KB909_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6838179.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11278..11649)
                     /locus_tag="KB909_002178"
     CDS             complement(11278..11649)
                     /locus_tag="KB909_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838180.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4175 a         1984 c         2232 g         3388 t
ORIGIN      
        1 attggtcgtt gaatgggctg aatagtagtg tataaaacaa ttttgtggag cgtgaagctt
       61 ttatggtaga ggaaaatacg aataaagtga tgttgataaa aagattccta tcttgaatat
      121 gaatcgagat gtcttgaaaa tgaatgagtt tgaccaatca ttatcctatc gaaatttaca
      181 gtttcgttcg attggtctgt caattaatga aaaagtaaaa aagaatatgt tctaggaaga
      241 gggcggcaca tctaaatttt taagtaacgg acagttcaaa tatcaagcat tgaaagaggc
      301 tatcctactg tttgaaggaa tacgaatata taaaaacgac aaagaggaaa aagtagttca
      361 ttaaatccct tcaagtgatg aaagaatgag atctaataaa acctgatctt tcatctgttt
      421 ttttaataac gtaataattt ttttattttt tgtgctttcg ccgttattgt agagtgattt
      481 agcattctta tttttaaaaa taactgtgtt atatattaaa aaaggcataa tagttataag
      541 cttttttaaa gaatatttag aaattattaa ttttcgtctg aaaacaaaaa aagaaagcgt
      601 tattatttta gtctattttc agggggggaa ccttatgata aaaaaactat ttttactatc
      661 aatattaacg ctagcaatgg caggttgttc tgactctggc ttagcaactg aactgatcac
      721 aaaatcaact gaagccacga cagaggagtt aaaatgtgga aacgatcaca gtgactacag
      781 aggcttaaat cgacgatgca tgggaatatt aggcagaagc aattgtaagc atcgatgtag
      841 taatcgaaga aggtgtagaa gaagcaacag aaaaatcaaa agaaagatca aaagaagcaa
      901 tctgtgctgt gcatcgtata cagacgtcga agatgcggta cttttaaacc acgtcaggag
      961 atgttcattt atgtctaggg aagttggcga tgaaccaaaa ctagagtacg cttttagttt
     1021 tgcacgtgag gatgaagata accctaaaac ttacgacatt ttagcttgat ctaagatggt
     1081 taaagctttt taatgaagta agaggagata gaaggctttt ctagttatat taggtaagat
     1141 aaattccttt ttgctccaaa tttgctaaac attctgctag ataaacttca tcgtgttccg
     1201 gataaatcgg cacgttgcgc tctacagtag gtaaatcaaa aaatgcttcg catgatttgc
     1261 cacgatacat aggatttttc cactctggtg ctgggctgta accacgtttt tccatttcat
     1321 ccatgacaag ctgatgatat tggaataatc tataaggaga atagtgaaaa acataatcca
     1381 cagtagcatg tttctttccc cagccatttc ctcttaatgc acagcattcc cgatgttgtc
     1441 ctaaaagctg ttgacgagga agctttgaaa tcaatttttc atgccataat cgcatagaaa
     1501 tgtctccttt atatatagat tgttaacctt agacgttaaa tgaaaaaacc agcaccaagg
     1561 ctggaaaaaa tcacttcagt ttgcttgctg tttctgagcg accaattagg taatcaacgg
     1621 aaatatcgta aaagtcagcg atatagatta attcaatgat gcttggaatt tcttctcctt
     1681 cttcgtactt acgatatttg aataaaggaa tacttaacgc gctagaaaca gctacttgag
     1741 ataaagatcg gccagttctt aagaaattca gacgacaacg taaagtatcc agtaaaatag
     1801 cttcttcgat actcatttaa tcacctttca ttatagtaga atagttataa tgactataga
     1861 aagctacaca tgcaatcaat agtactcaat gttttttatt taaacgtatc aaataaagaa
     1921 tgacgatcaa taaagacaaa accagtcctg ataattcttc tataaaaaca ctatcgggtt
     1981 caaagtagtt gtaattaaaa actttccaca taaagtagat agccggaaga gtcaaaatag
     2041 ctaaataaaa ccgttctttg ttccaattca taagataaac aatacttgcg accagtgcga
     2101 ccgcaggcac ccaaaacaaa actctcacca acgtaatcat gtaacggact cctcaacgat
     2161 tcatataata aaagataaca tgttattgca tacatcacaa atgaaatgct aggaaaataa
     2221 aagaagaata gatcaatgaa aaatgaaaaa gcagaacagt tttctgctga taagcaggaa
     2281 ctgttccgct gaatgtgtct tatctatcga gaaaaaatca atggattgat atctaagtaa
     2341 ttcaatacat ataaaaagag gacgatcgca ttcactaaaa aggaaagaat gatgatccca
     2401 tagcgaatgg aaacatattt aacaaatact tttgtttgaa tacgggcata tctttttcct
     2461 ttatagctga gcatcatgac aagaagcaaa agggtaatca caccttgaaa aatcattcca
     2521 ataaacagaa ttcctgaggt ttgataattt aattggagaa aataagctgc tgccgcaact
     2581 aaatcgaata aaatcgcaat aaatggcaaa ataatcactc ctaacattga gaataaataa
     2641 aagaataaca ttttttctaa aataagcaaa taaaaattaa agtaacaaaa tagttatgac
     2701 acaagtaaaa gaaataagaa taacaatatt attttactta tattttgaaa cttgtgagag
     2761 tttgtcattc gtgctatagt tgaaaagtaa caaaaataaa ttttatttat gatgtacctt
     2821 tagctcagtt ggttagagca gacggctcat aaccgtccgg tcgtaggttc gagtcctaca
     2881 aggtacataa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaagtaa
     2941 aaacagcttc ttatgttttt acttggctgt tcttattact gcagatgcaa gcttttgaat
     3001 accgtttaag gaagaggttg tgaaatcagc gttttgacct gagtattagc ttaacaaacg
     3061 gaaaaatagt tcctcatatt ttgccgtttg ttaagctaat accgagggtc agctgattga
     3121 acaccattta agaaagaggt cgtgagcctg ccgtttcact ctgtgtcata aaaaagccaa
     3181 tctactttga tagaaaaagc acgtaggact aaaacagttc tgcgtgcttt ttttattgtg
     3241 tgttaaatat cgtaaatgaa gatagatatt tttatgattc gacgatagag acgttgaaat
     3301 ctttcaacag ctctaaagcg gattctccgt gttttctact ggagactaac attggatcaa
     3361 caaaaaagtc tgcttcagga aaagcactct gcaggcctat cagattagag agtacacaca
     3421 agtttgtttc aatcccgact acttcgatct ctttttgttc ttctttgctt tcaaataaag
     3481 tttcctggat ttcagctaaa gtttcaggtg gaatcgtaaa gtaatacttt ttaatcactc
     3541 gttcattttc ttgtggagaa agaagaggga tcaattgcaa atcttctcgt tcttcttctt
     3601 tgtccttcag ttcaactggt atatcccgtg tgaagagaat atattcatta ttttggcgtg
     3661 ctttagctaa tctttgagca atacgttctg ccaattgatc tgactctgga atataaaatt
     3721 cgctgtttgg atcaagaata tgattttgca tatcaataat aactaacatt ttctttcctc
     3781 ctacattcat atcgtcattt tattcttttt aatagaagtt ttttaaaata taagcaacac
     3841 cagcttcttc attcgtcagt gttacttggt ttgcaatttc ttttacttgt cgctgtgcat
     3901 tccccatcgc aatactcaac ccgctgtaat tcaacatagc aatgtcgttt tcttgatcgc
     3961 caaaagccat gatgtcactc gattcgattc caaggtaatc cgccagaaaa acaagtgaat
     4021 gagctttagt gatacctgta ggcgtgattt ctaagaaatg cggatcagag aatactgatt
     4081 ggataccatc tgcttgcaga tctctttgta gcttctgtag tttttcttca ctcttatctg
     4141 ttaatgctaa tttaagatag ctaagagaag gatcttccaa catatttaaa atttgatcaa
     4201 aagaatggtt ctgtaaattg aaatgttcat aataagggtc atctttgact agatttgatt
     4261 catcgaatgt cagctgatca tcttgggttt ctcggctagc aatgatggat attttcgctt
     4321 cttgagcata gaagaaggct tttctcagtg tatcgctatc tatttttgaa cgtctgagaa
     4381 ctttcgccat ttttccatcc ttcatttcag caatcagtga accattggaa gaaatcaaat
     4441 agccaccgat tcctaattcg gaaaaaatat ctttagcaga aatgctgttc cttccggtag
     4501 cgacggttac gattccgcca ttttcatcaa atttccgaag tgcttggata ttttcttctg
     4561 gtatctttcc atttcgatca agcaaggtac cgtctaaatc aatcgctgct agtttcattt
     4621 tatcttccta ctttcttttt acatatctat tttcctgtta ccttaagatt aaatgagaat
     4681 ttaaaaaaat gaaactaact tgctttgtca ttatgaattt tttcaaaaaa cattcttaag
     4741 aaaaaggtgg ctatatatag tagtttttgg tcaatacctt tgaataaaaa gccatgaaaa
     4801 acgaatagtt agcgcttacc gatgcgtttt gtgataaaaa aattttaaaa tattcaatga
     4861 aaacaaagca tatattttgc tttaaaacca aatgaggaat attctagatg tagaacaggt
     4921 tagaaaaaga ttagaaaaag gagtgatttt gatggagaag agatacggcg tagttcctgt
     4981 ggtaactgct tcagacgaaa attatgctcc ttacttgagc gtgatgatcg caactgcatt
     5041 agaaaattgc aataaaacaa gacgcataaa attttatgtg attgacgatg gtctatcaga
     5101 atatagtaaa gaaggattgg aagaaacggt aaataaatat tcaagtaatg caagtatcca
     5161 attcctgaca gtggaaaaag atatctacga agacttccta gtcagtgacc atatcacaac
     5221 taccgcttac ttaagaattt ctttaccaaa cttattagct aaagaggatt ataagaaagt
     5281 cctttactta gattcagatg tgttagtact agacgatatc gtaaaactat atgatgagcc
     5341 gttaaatgga aaaacaatcg gcgctattat cgatccaggc caagtgaaag ctttggaaag
     5401 attaggaatc gattccgatg acttgtactt caattcagga gtgatggtga ttgacattga
     5461 tcaatggaat aaaaaagaaa ttacagaaaa aactatccat tacctcagtg aaaatggcga
     5521 tcgaatcatc tatcacgacc aagatgcttt gaatgctgta ctttatgaag attgggaaca
     5581 acttcatcca aaatggaaca tgcagacttc gctgattttt gaacgtcatc cagcaccaaa
     5641 tgaaaaatat gaacgtcagt ataaagaagg aaatgaaaaa ccttcgatcg ttcactttac
     5701 aggacatgat aaaccttgga atacgttgaa agatcatccg tataccaatt tatacttaaa
     5761 aaaattagca cacagtactc taacgaaagt aggcgagatc aatgaataaa aaagaaatag
     5821 cagtagtcgc aagttgtaac acaaaattcg taccacattt agctgcatta tttgtctcag
     5881 tattagataa ttgcaacccg tctaaatttg ttcggttcta tgtgattgac gatgatatcg
     5941 attttgaaag taaacagctt ttacgcttct cagtgaaaaa cgcacgaatg aactcagatg
     6001 tggaattctt gaaaatcaat aaagaattct ttacaaatgt ggtaatcagc gatcgtattc
     6061 cagaaacagc ttattatcgt attgcgattc cggaattgtt ccgcggcaca gaagttgaac
     6121 gtatcttata tatggattgc gacatgatcg ctttacaaga tatctctaaa ttatggcgtc
     6181 ttgacttcgg tgattcaatc gtagcagctg ttgaagacgc tgggttccat caacgactgg
     6241 aaaaaatgaa aatttcagct aaatcaatgc gttatttcaa ctcaggtttg atgctgatca
     6301 atgtgaaaaa atggttagat gaaaatatta cgcaaaaagt attagatttc atcgaacata
     6361 atccagaaaa attacgattc catgaccaag atgcattaaa tgctatctta catgaccgtt
     6421 ggttaccact tcatccgcgt tggaatgcac aaggctatat catggcaaaa gcaaaaaaac
     6481 atccaacagc agcaggtgaa cgtgaatacg aagaaactcg caacaatcct tacattatcc
     6541 atttttcagg acatgtgaaa ccgtggagca aggattttga agggccaacg aagaaatatt
     6601 acgaaaaata tgcagggatg acggctttcc gttgtgtagc taaattccct aaatatccaa
     6661 aatatgcaaa agttcaacca aaaacagatg tagttgttaa ataatagaag accacaactg
     6721 aagaggggga gtaggaatgg aaattacaat gtctaaaaat gcagtagaga cgttaattga
     6781 aaaggttggg gaaaatacaa aaatcgcact cgcgcttatc aatgattccg atccatttct
     6841 aagggacaaa ggtgcttttg caaaaggcag cttttttcaa atcattcctt ttgtttcgga
     6901 atttggagaa tatgcgacta aaatcgagca tccattattg gacatctata catctaaatt
     6961 agagcaaaat tatttcggta aacgattgaa catggacttc aacaaacagc ttgacagctt
     7021 ttcattagaa aatgaaatcg cagtactcga ttataatatc aaattaaaga actgcttctt
     7081 cagctaatag tttcgagaaa gtccaaaaag gaggtataca ttgagatact actttgtgga
     7141 tgaagaaaag aatgtaatag aaacagatga aaaaaaatat aattggctcg tacttgatag
     7201 tgcaaagccc gaagagattg agcaagcaat cgaagaattc gagcttcctg atgatatttt
     7261 cgtaggaacc gaatatccgg aagaagtttc tcggatggag cgcctttatg agacgaaact
     7321 agagcatcca ttttctttgg tagtgattaa tctagatcag tcagataatc gtatcgaaaa
     7381 aaaattaacg ccaatatctt ttgtactttc cgataatctc ttgattactt gtatcgatag
     7441 aaaaaccgaa tttgtggatc ggctgctgac aaagcatgga aatcatttaa actcgtttga
     7501 aaagatcatc acgtatacat tattagatat ttacacccat tacgtgaaag aactaagaga
     7561 gatgaaaaag cgaattgacg ctttggataa agcagctcgt aaaacaacgg aaaatgaaga
     7621 actgtataaa caggcagatc ttgaaagaga catcgtatat atcgatcata ccttaagaga
     7681 tcaacgggaa acaatggatc aattatggaa ttctgaaact ttcatcaaac gtttagacga
     7741 tgaacagcta ctctatgatg tccatttgag acagcgacaa acagaaaaaa tgatcgagat
     7801 ctatcgagat ttattagaga gtattggtga tctattcaac gggatgatgg acaataatct
     7861 aaatcatatc atgaaatatc tagattcagc tgcattaatc atttccgttc cggcgttgtt
     7921 cgcagggatt tggggaatga atacaggagg attaccgggt aaaagttctg ctctaggctt
     7981 tatactcgta gtctttggct ctttgatagc agcagtagtt ttaggttacc atttataccg
     8041 gaaagattat acaaattaaa gaatctattt aaaacaggta tcaaacaaag aaatttgttt
     8101 tggcaataca atttaaaaac taggaggaat acagcaatga cagaaccaaa attaatcgac
     8161 ccgcgaaact tgtaccatac ggagaaattt cctaaacaag atcaggatac accagcttta
     8221 cagcagaata tgattcctgt tcctgattgt ggagaagaat cctatgaagg caataatcaa
     8281 ctagaaaacc gccgtgtact aatcactggt ggagattcag ggatcggtcg tgcagcagcg
     8341 attgcatttg ctagagaagg ggcagatatc gctcttcaat tcttcccagg agaagaaaaa
     8401 gatgcagagg aagtagcaaa atacgtgaaa gatgcaggac gtaagattgt cttactacct
     8461 tttgatcttc gtgacgaaca agcacctaaa gaaatcatag ataaagccgt gagtgaactt
     8521 ggcgggctag atacgatggt actaaacgca ggacagcaaa tttcttgtca gtctattgct
     8581 gagttaccac ttgagcaagt caaagacaca tttatgataa acatcatcgc tatgtttgct
     8641 ttagtgaaag aagctgttcc gcatatccca gcaggaggag caatcgtaac aacaacttct
     8701 gttcaagcat tcaatccaag cgaacattta ttagattacg cagcaacaaa agcttcaatc
     8761 gctaacttta cgatcggttt agcaaaacag cttgcaccta aaggaatccg tgtaaatggt
     8821 gtagcacctg gtccaatttg gacaccatta caactagacg aaggacaacc ttctgattcg
     8881 atccctgaat ttggtcagca aagtttacta gaacgtgcag gtcagccagg agaattagca
     8941 ccagtttatg ttttcttagc atcgaataaa gcaagttatg ttacagccca aatttacgga
     9001 gtaactggtg gagaagcgat caacttataa gaagttgatc gtttcacccc tatgaggagg
     9061 tgcgaaaatg aataaaggtg taaaaacgat cggagtgatc ggaacattac ttttgctatc
     9121 tgtgcttttg tttgcgatac tattaagtgc aacctatcca ttgccttttc agctagagaa
     9181 gtttcgattc ttttccatca ctaattcata cgtgcaacaa tatgtatttt ggcttgccgt
     9241 tgcatttgct attttgacaa ttatcacgtt acttgttttc ctgttttatc caaaaacaat
     9301 cggaaacttt ctactgaaac atggtgatgg ggagttgacg ttggataaaa aagcaattga
     9361 aggaatggtt cgttctcact tgcatgaaga tgaattcatc cattcaccaa aagtaaatgt
     9421 caaagcaacg aaaaacaaga tcgccgtcaa tgtaaaaggg gagttgaaac gaacttcagc
     9481 actcattggt aaaacaggaa cattgatgaa agaaatcgaa aatgaagtac aacacatatt
     9541 gggaacaaaa gagccagtga aagtatcggt gaaatacaca ggctttgaag aaccagctaa
     9601 acgaagcaat gaccgcaaac gagtagaata gggggggacc aaaaatgaaa gaactatttt
     9661 cgacatacaa gctccctatc atctttgggg tacttggatt gatattagcc gttttatgga
     9721 tcaccgtggg ctttttcaag accttattga tcttgatcat ggcagcgatc ggcgtcgcta
     9781 tcggttttta tctgaaacaa acgaaaatct tagatcacta ttttaaatct taggaggaaa
     9841 catccatgaa taacaataac aaaaataata acaataaaat gaacaaccaa aaaccagtgt
     9901 ctgcacatcc agacccaacg acaccaaacc aatcaaatgg tgtgaacgat gaaaagaaca
     9961 aaacagcacc agtatctgca catccagatc cagtagtccc taacgttcaa caaggagtag
    10021 aagagaagaa acatgatgca gaaaagcatg cacctcatca tccaggaact ccagaatcta
    10081 aagttccaga acaacatgat gcaatcgatc cttctaaacc tgtggaagag caaaaacatc
    10141 cttctgacca tgcgaaagca caagaaaaac ttagttctga ccacacaaac ggacaaggaa
    10201 aacttggttc tgatcataca aataaccaag gaaagcatga ttctgaacag gaagattcaa
    10261 tgcgcggtga gctgaattat gaagataaag ttgtgcaaaa aatcatcgga atcgcaattg
    10321 aacaagtaga cggtttatta tctgcaaacg gtggtttctt ctctaatgtg gcaggaaaac
    10381 ttgtgaatac agataatgta acggctggga tcgaaacaga agtcggtaaa aaacaagtag
    10441 cagttgatat ggatgtcatt gtggaatatg gcaaagatat cgaaaaaatc tttgaagaaa
    10501 tgcaagaagt aatcggcaaa gaagtaaaaa atatgacaca tttagaagtg atcgaagtca
    10561 acgctaacgt agtggacatc aaaacaaaag aagaatttga aaaagatcaa gaaacggtgc
    10621 aagacaaagt aactgacgca gcgaaaaaaa ccggtgaatt tgcttcgaat caaacagata
    10681 aagtaaaatc agcagctgga agcggcgcac aaaaagtaaa agaaaataca gaaccacggg
    10741 ttcagtaata aggaagtaaa acattaggag gaacgaaaca tgggatttat ttggtcactt
    10801 atcgtcggag gaattatcgg agcaattgca ggagcaatca cgaataaagg ttcttcgatg
    10861 gggattattg caaatgtcgt agcaggttta gttggatcag cacttggtca agcattatta
    10921 ggttcttggg gaccaagtat tgcaggaatg gcaatcgtgc catcattgat tggtgccatc
    10981 attttagtac taatcgtatc attctttgct cgaaaactgt aaaaagactt ttaaaaagag
    11041 gtcgtgaaaa agctgttctt catcaagtaa taagaacagc caaacaaaaa tagcttctca
    11101 tatttttcat ttggttgggc atattatcga agatgcaagc ttttgaacac tgtttatacg
    11161 gaataagagg ctgtgacaag acttttgtca cagcctctta tttatgcggg caaattccca
    11221 attagatttt taaaagtttt tccttaaatg tgtctttatt gatacagaga agcttcttta
    11281 ataaaacaat gcctccctaa attttcttga gataggaaag gtgaacatac aaaataatac
    11341 gaccactttg aaaacccaga tgatccacaa atggatcgta tgatactgat gaagtaaaaa
    11401 gcaatggatc agaaactcaa agagattgaa aaagacaagg aagaaataat atctcttttt
    11461 tactcttgtc tgttttagcc aataatagct cgtaaagtaa tctagacaaa caaatagaag
    11521 taaacaaagt ttcgtaagag cagcaatcgt atcatgttgc tctgctagac gattgacgag
    11581 caggaaaaat gttggtaatg gaatatagat cacgagtaat gaaagaaaaa agtaaacaat
    11641 aaatggcata ctattcctcc taattgtgtg agttcgccct cattttaaaa taacgatatt
    11701 tgtttgtgaa gctttttcgt gtcgtaacaa atgttatcta atgtattttt aaataaataa
    11761 tcattattat caaaataat
//
LOCUS       DADVXK010000086        11778 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.087, whole genome shotgun sequence.
ACCESSION   DADVXK010000086 DADVXK010000000
VERSION     DADVXK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.087"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(32..1384)
                     /gene="celB"
                     /locus_tag="KB909_002179"
     CDS             complement(32..1384)
                     /gene="celB"
                     /locus_tag="KB909_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6838181.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(1384..1902)
                     /locus_tag="KB909_002180"
     CDS             complement(1384..1902)
                     /locus_tag="KB909_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838182.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(1918..2244)
                     /locus_tag="KB909_002181"
     CDS             complement(1918..2244)
                     /locus_tag="KB909_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBB6838183.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(2257..4236)
                     /locus_tag="KB909_002182"
     CDS             complement(2257..4236)
                     /locus_tag="KB909_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6838184.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(4257..4571)
                     /locus_tag="KB909_002183"
     CDS             complement(4257..4571)
                     /locus_tag="KB909_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBB6838185.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4739..5032
                     /locus_tag="KB909_002184"
     CDS             4739..5032
                     /locus_tag="KB909_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBB6838186.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(5110..6222)
                     /locus_tag="KB909_002185"
     CDS             complement(5110..6222)
                     /locus_tag="KB909_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6838187.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            6609..6788
                     /locus_tag="KB909_002186"
     CDS             6609..6788
                     /locus_tag="KB909_002186"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838188.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            6982..7152
                     /locus_tag="KB909_002187"
     CDS             6982..7152
                     /locus_tag="KB909_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838189.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(7576..10976)
                     /locus_tag="KB909_002188"
                     /pseudo
     CDS             complement(7576..10976)
                     /locus_tag="KB909_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         3498 a         2502 c         1938 g         3840 t
ORIGIN      
        1 ttttttgtca cagttccttt tttcttagaa atcattttaa cttttcacta gctaattctg
       61 ctgccttttc tctttcttca tttaataatt tattatcata gaatttgata aatgggaacc
      121 agataatgaa tgcgatgatt gcacaaatga ctgctaacac agcagctttc caatcaccac
      181 cactaccaac aaatgctccg atcccgactg gtgaaggcca cggcatctgt gcaagcatcg
      241 gtttgacgat ttccagccga atggcaaaat aagcgagtgt agcagaagcc atcggagcta
      301 agaaaaacgg aaccgctaaa tagggattgt agacgattgg catcccgaaa atgattggtt
      361 cattgatatt gaataatcct ggtacaagtg aggcttttcc taacactttc agctgatcag
      421 atttcgcgag gaatgcaata aagatgatca atcctaaagt cgcacctgat ccaccaacgg
      481 ttacataaga attgttgaat tctcctgcca acggataatt tgcgccttgt gcgttagctg
      541 ccatattagc taatacgatc ggggtcaaga aagaagtgat gatattcgct ccatggatcc
      601 ctacgatcca caatgcatgg atcaagaaat aaatcaccat gacaccaagc catgtattcg
      661 tcaactgcgt aacaaaccca aatgggatag caatcatttt gaagatatcc gttcctagtg
      721 caactaataa tccattgatg atcatcacca caaacgcaat gacaaatgtt gggatcagag
      781 cagtgaaaga acgagaaact cctggcggaa caacatctgg catttttatg acccaatttc
      841 tcttgacaca catacaatac aattcgaccg caataatcga cataataata gctgtaaaga
      901 ttcctgaagt tcctaaacgt tcgacaaaag agcccatcct aataccattt actacagttt
      961 ctgtctcatt gatagaagca atcaagctga ttttaccatc agtcatgatc aattcaggga
     1021 tacacataaa gaatgcaaaa acagatagta atgcccccgt gagcggatta acatttaatt
     1081 tttgttcatc tcgttcaatt gacgttaatt cataagcaaa cacaatggca aagtaaatag
     1141 ataaaatccc catcgtcatt gtattgacga tcatgtacaa gtcactaact ttgaaaaaag
     1201 ttgcattaaa aaatccttct aaaaatggga acggtaatgg caaaatattt aaaaccaaaa
     1261 acatcgagcc tacaatcgtg aaaggaatag aagccatccc cgctgccatg acagcccgaa
     1321 cgattttaag ttgcgcaatt ttccccatag gtcccatcag gtatttctgc aaaaaatcaa
     1381 acattagtta ttctcctttc ctaaatataa cgctttttca tattgtttaa tacggatata
     1441 ctgttggtct tggttgagtg aaattttctt taaacgatac tgtataaatg cactggcaaa
     1501 aataccgctt acaacaagaa tgaaaacaaa taactgtcct ccattgttat ttgccataaa
     1561 aggatacaag aatgtaaatc ctgaggtaaa caacactgga atcactaata aattaaagac
     1621 actctggaac aaaaaatacc actttgtcca tggaacgttc gtttggtgtt ttcgataaag
     1681 ctttacttgt tctcctactg caggcaaaat agctaaaatc agaatcatcg gtaaactact
     1741 tcctaaactt ttagctgata gaagcagaat catccattgc atgttcatga aaaagaaaaa
     1801 ggcagtcagg taacgtacga ttagataacg attgaaatac atgtttttca aactaagttg
     1861 ctttttttct aattcgattt tcctttttac tgtatcctgc acaatgatcc ttcctttcta
     1921 tttatttttt tgatacaaat aattcatttc ctgtgcaact tccaataatg tcatcgtcgt
     1981 catcagatga tcttgtgcat ggaccatgat aatttccatt tctatttttg tcccgctggc
     2041 atattctttc agaagttgag tttgtgactg atgcgcatga agaatctctt catttgcttg
     2101 tcgcaacttc tcttctactt cttcaaacat ctctttacgc atcgagcgaa atgcttcatg
     2161 tatcagtgtc cgtgcatttc cgctatggaa aatgatatca aaagaagtca cttgtagtgt
     2221 ttcactgttt attttttcag ccatctgttt tcctccttat tcgatcagtt tgataaattt
     2281 actgctgaaa ttctcaaaaa taggttcagc taagatttcc tgctgtactt ttagctggtc
     2341 aactaaccta acgattgctt tagtcacgac cgtaattcct tcattttcga cataagaagg
     2401 cgaaactaaa aaaacaaaat gaatttcttg atattgatcc cactgcatcc cagaaggaat
     2461 caatgcaacg gctacctttg tttcgattcc aactggaaca gcgggatgtg ggactgccac
     2521 tgtatcactg aatatgattt gtcccatatt ttcacgttgc tggatctgct ttcgcatttc
     2581 tcttatatat ccttcttctt catttatgct cagcttttgc agcaaatcat gaagaatttc
     2641 ttcctttttc ggttcgtacg tataagtctt gaaaaatttt tcagacaact gttcggtgta
     2701 aatctgcttt ttttgctgta gagaaaatgc tggtatcggt ctatctgagg aatgataggg
     2761 tatagattct ccaactacct ttcgtatttt acgaacatca tcttcattca aaaaaatact
     2821 gacatgtaaa actggaattt tgaaaaacat tgtcgaaaga tcaatagaag aaataatcag
     2881 gtcgattcct tttaaagttg tttcattgat ctcataatag ccttttacac ttaccactgt
     2941 aatattttta ccgaattcac tgactacgcg attctttaat agttgggcac tgccgtaacc
     3001 cgttgcacag ataatcaatg catgtagttt atgcgcagct ctttcttttt ccaatgccgc
     3061 catgagatgc aaagccaaat aggcccattc atcttcattg atggtatagt ttttcaaagc
     3121 cggcatgttg ctgaaatgcc tttttactgc gtcaaagact ttgggatttt ctttctttat
     3181 ctcctcagtc aatgggttct caatgcgaat acctcggctc aatcgaatca tcatcggtga
     3241 caaatgatcg agtagtccat tgaaaagctg gagatcctct actaatgaaa aatgaaattc
     3301 ctgagacaat cttttcagaa ctttcgctaa ttcctttgat agttcctgat cattttgatt
     3361 ttctttgtga ttcgacttag ccatgagatg taatgtcaaa taagcaattt cttcttcggg
     3421 aaacgataca cctgcgatta cctcaatacg ttgaacgatc cgctgcgcca cttgatactc
     3481 tactcgctta gaaacttctt gttcgatgcc taattccttg atttcaaacc cttctcggag
     3541 ccgtttgatc cccaaagcca agtgtaaagt cagattctgt atgataaaat ccgaaacttt
     3601 taacttagct tctcttgttt catcgagaat gataatgact agctcttcaa aactgatgtc
     3661 tgggaaaaaa cggctttgcc ctaaatattc tttcaatgaa tttccataat ggtttccaaa
     3721 aaaagtatcc atgataaaat gccgtcgatt tctttcttcc ccttcgatcc atgtcccttg
     3781 accatgctta gaaacgattt ttagtgaata tggaatcaat cgctccttga tttcttgcat
     3841 gtcctttgtc aaactggaac gactgatata aagctcttct gccaaatcat ccataaaaag
     3901 aatggcatct tccaaaagca attggttcaa tatatacttt tgtcgatctt cggactcata
     3961 aaatccttgc ggttctctag catatccagg tactatttct tgccgactca aaaacaagtc
     4021 aaatgtcagt ctttgtaaaa tatgcagttg gtagccataa cctggtttag caatgatctt
     4081 acctccgttt ttttctacta actctttgat ccgctgcaag taattacgga ttgtccgatc
     4141 agataataac aattcagaag ctaaacgttg actggtgaca tactccttct tgtgatcaat
     4201 caaatatctc aacagcaatt tttccttctg tttcattatc atccactcct attccatcat
     4261 atgttctctt cgatcacctc tgctaacttc tggatgcctg tagggattgg gacatacgct
     4321 tggaaaggga tactaacaac aggctttcca acagattctc ctaatttttt gaatttatcc
     4381 aaaaacatcg tcgtttgcgg gctgatcaga aataaatcaa aatcactatt cttaatcata
     4441 ttatcgcctt ctgtagctga aactgcatct acgagtacct cttctctttt ttgcttaaag
     4501 aaatccgttg tctttgaggc catcatcgag gatgacattc ctgccgcaca aataatcaat
     4561 gcttttttca taaatcaatc actcctttta tttttataaa ccaagcatat cttgtaagcg
     4621 ttttctattc aaaatatata tttccgtagc attgcggaaa aaatgtgtat catatcttga
     4681 ataataattt ctggcaccgt gatatactag tgatagaatt ttttcaggag gggatttagt
     4741 gagtatcaca gtgaatattt tgtatacaag tacaaatgga caagccagaa aatttgcaga
     4801 agaaatggtc gaaagaaaca ttgtcaaagc gattcgtgca gaagaaggaa acgagaaata
     4861 tgactattac tttccactag aagatccaga atctctttta ctgatcgacc gttggaaaga
     4921 tgaagaagca atcgaaaagc atcacaaatc cgaaatgatg gctcaaataa acgaactccg
     4981 taaaaagtat aaattaaaaa tgaaagtcga acgtttcact gatttaccgt aaaaagatac
     5041 acatggaatg atagcaattt atcatccatg tgtatcttca ctttttcctt attttttatt
     5101 cgatctcatc taatgattca aaccgtgttt ttctcttatt tttcggataa gtatttcagt
     5161 caccccaata tacatgattc ctaaacatac cccaaggata ttctcaaaaa tgcggatcgt
     5221 tactgctcct ggaaccccga ataaactggc agtgattgcc aaagcaccaa aagaattaaa
     5281 aactgtttta tatctatagg tagaacaaac acctaaagct agaccaccta atataccgac
     5341 ccagttaaaa ggaataaatt ggctgatacc aataaataaa acacatccaa tcaatgagcc
     5401 aatgattcgg tctactgctc gttctttgaa accaatcgac atcaatccat agctagatac
     5461 aatagaagaa aatgcaaacc ctgcccacat caatcgctga aaagggacat actctcctgc
     5521 aacgatcaaa agactaatgc caaatgcata gatgagcatc caaatttttt cctgcgaata
     5581 catgcctttc aaaaaaatct ctttaaacaa gcttttgtct ttgttctttt ctcgatgttt
     5641 tctgtaaagg agaactgaaa accaacaaaa aaacaaaaat aataagctac ttgtttgtgt
     5701 aaagaaattc ttgttcaacg aatctttagg taacgaataa acaataaaga gatatgaaaa
     5761 gccgtacaaa gaagcattcc ccattttggg atcactagcg gttgccatta atatgctgct
     5821 tagtaaaata aaatgaatca acatgcccat aactgaccat ttgatcagct ggacatacgg
     5881 tgctactaat agtgagaaca tgacgattgc taaacctatg atcgaatggg aaatcttata
     5941 accaaagtca acaaaacgaa tactcatcaa catacagaat aaaaccacag cgtatggttt
     6001 atgcttcgat tcaaataatg ttgtaattat aatgataaaa caaatggcaa acaatacgat
     6061 gaataatgat cgtaaaaaca atgaacaaat atacatgcac ttttcttttt tagaagctgc
     6121 ttctcgtatt ttttgtttta aaataaacgg atctagttgt agagactgat aaaaatccac
     6181 ctgttgtcgt cctttctttt tacttttatt ttttacagtc atctatgaca ggttgtaaat
     6241 actatggaac atcatatggc gttgtcattt tcttgtcaac tatttttcct attcatgttt
     6301 ttataaaaaa acatatcgtt ttcttgtatg attaaatcac cacaaaataa acaactgaga
     6361 gaacgatatg ctttatgaat ggttctatca aaaaaattct gagatcaata gacaaaaatt
     6421 tgatgattac agaggtctct tacgaaacct tacagaagaa aaaaacattg atcgttgctg
     6481 cagttctctt ccctgctcca tgtgtctgta gaaattgtgg ttctgctgtg gtagatggaa
     6541 ataggaaatt aatggtggtg aaaaacaaga agaaggaaac cattgtccac tttgaataat
     6601 ataatcatat gccaatggtt atacgcctaa aaaagcagcg ctatacctgt aaaaactgtc
     6661 gaagccattg gaacgctcaa agttatttta tccgtccaag gcactcgatt tcaaatcatg
     6721 tcagacataa aatcacttct ttactgactg aaaaagtgtc gttatttttt atttcgaaaa
     6781 gttgttaggt atctttgaca accgttattc gcacattgaa agagttgaga agctatttac
     6841 caaagtcttc caaaagaatt ctgtcttgag tgttgagggt tgtgaatttc gttctcacgt
     6901 ttccgttgag gataaactga gttttatttc cgcggatggc gagacagaaa aattaatcga
     6961 gaaaatttac ctacacaaaa aattcctcga ttaacaaact atttccttag ctgcactaat
     7021 cctaaagaaa tagaattctt agttacagac atgaacgcca cctactttca gctcaccaaa
     7081 catgttctac caaatgcgaa attggtgatt gatcgattac ttggtttttc cacgcctttc
     7141 aaggaggcgt aacctttatt cacgagttgg ttgaagcttt ccgagacaaa agacccgact
     7201 tgtttttctc cttattgaca aagagccatt aaaactagag aaaaaattac aactgatcgc
     7261 tgattatttg tagaaagaaa atcaaagtat tacccaataa acttgagtca ttaggcaaaa
     7321 aacactgcga aactcaagaa tgattttcgc agtgtttttg tatatttttt attaactagt
     7381 attactacaa aggtttattt ttcacttctc aacgcagcac aaaattgtct ttacttattt
     7441 actggttggg ttcaaccttc tctactccga tactaatatt tgtttgtata ccccttctaa
     7501 aatcggtagt ttccattcaa ttgatgggta ctagttgatt ttaaaaacta tgcttattca
     7561 attttttatt ttagctcata tatttcgttt ctttctaaat tttatactga tgaaaacaag
     7621 tagcacaccc aatattgaca atataaactg gctaatgatg gtttctccag tttttggaag
     7681 atgcttattt ccactgcttg ttggattgtt tcctcttata tctgagctat cagcaacttt
     7741 tctattctct tttgttaaaa agatcgccac ttcttgttct ttttcgatct tgaaagttac
     7801 tggtgtcgca tccaattcat accctattgg cgcttgagtt tctaccagct gatatgctcc
     7861 tggtgctaaa ccgtcaattg ccagttttcc atcttctcct gtagttagac cggtttgtag
     7921 cgtttctcct tctcggttct gtaactcaaa aacagctcct gcaggatttc cccgctttgg
     7981 tcatcgatct ttgtcaacac gacaccgcct ggtgtaagtc ggttttcttt cgttaattct
     8041 accaccgctg tctgacttct ttcgatctca aactcgattg gtgtcgcatc taattcatac
     8101 cctattggcg cttgagtttc taccagctga tatgctcctg gtgctaaacc gtcaattgcc
     8161 agttttccat cttctcctgt agttagaccg gtttgtagcg tttctccttc tcggttctgt
     8221 aactcaaaaa cagctccttg caggatttcc ccgctttggt catcgatctt tgtcaacacg
     8281 acaccgcctg gtgtaagtcg gttttctttc gtcaattcta ccaccgctgt ctgacttctt
     8341 tcgatctcaa actcgattgg tgtcgcatct aattcatacc ctattggcgc ttgggtttct
     8401 accagctgat atgttcctgg tgctaaaccg tcaattgcca gttttccatc ttctcctgta
     8461 gttagaccgg tttgtagcgt ttctccttct cggttctgta actcaaaaac agctccttgc
     8521 aggatttccc cgctttggtc atcgatcttt gtcaacacga caccgcctgg tgtaagtcgg
     8581 ttttctttcg tcaattctac caccgctgtc tgacttcttt cgatctcaaa ctcgattggt
     8641 gtcgcatcta attcataccc tattggcgct tgagtttcta ccagctgata tgctcctggt
     8701 gctaaaccgt caattgccag ttttccatct tctcctgtag ttaaaccggt ttgtagcgtt
     8761 tctccttctc ggttctgtaa ctcaaaaaca gctccttgaa ggacttcacc actgccttca
     8821 gcatgtttaa ttagttcaac accacccgta tcaaggatgt tttcaatggt taacgtcact
     8881 tcttctatgg agtattcatt tataaaaaca tcatgtaccg tcgcatctaa aagataccct
     8941 tccggtgctt ctgtttctcg gacttgatag ctacctacag gaagcggttc acttaaaaat
     9001 tctccgtttt ctgccgttat accttcttgt atcacttgtg aatcgcttga taaaatttca
     9061 aattttgctc ctgccagcct ttggccattc tcatcagttt taattacttt aatacgccca
     9121 tcgattttcc ttgttcttac agtactcgta ttcaatcgat tgtcactatt cacaagcgtt
     9181 gcaaagttta aaatttgatc gccgaccgca tacgcctcta cattgacctt aaaagagagg
     9241 gtaaaacttg tcggaccacc aatcgtatta ttcgcactga aacgaactat tccattattg
     9301 acttcggcat caatgaaaga gggaatatct gatagaaatg acacaaattc catgccttct
     9361 tccaaaacat cttcaataac aagcgtattt cttgttccag aaaacatcga gacatgcaga
     9421 gtatacgtta gttcattttc attgagattg ataacatttt tgtccacact ttttcttaaa
     9481 gagattgccg gaagattact ttcagggatt ctcaagcggt agtctcggct cattacctga
     9541 ttattgtagg tcatactcgc tcgattccga gaaaacccat cctcttgtct tccttcattg
     9601 aacaagtcga catcggtcac ttcaagagca tattcaataa aatacgattg accctctgct
     9661 agattaccaa agtccacaac aagtgtattc gtttccttat taaaagatac tttgtccaca
     9721 aattcctcgg aaacataatg agttctaacg tttgcttcac ctggattcgt tacttctgcg
     9781 atccgaaccc cacctgaaat aggttctcta tttccagtgg aactccatgt agtcggattc
     9841 ggtgccaaag ttgttccttg cggtagtaca tcggtaacca ctacaccgtc ttttcgtgat
     9901 ccttcataat ttacctgcaa aataaattta ttactgttgg tcacgtcttg cccgtcaatc
     9961 agcagattcc caagatttcc ttggctgtcg atttctctag agccatagta taatttcgaa
    10021 aaaatgggtc ttgatgaagg aataggcgta attgaaaatt ccgtgtttgc tgctcgctca
    10081 gcataagtaa gactcacttg aaagtcatta tttggctcag taccgcctga ttgaaagaaa
    10141 gcaacttcaa acgtgatact gaatgtatac gactgagcgg cttcatttaa tccttcataa
    10201 tcaaaggtaa atggaaaaac aacgtctgtg ccttcttggt aaaatgccag tggctttaaa
    10261 ggtgaatcat cagcgacctc cactctaatg aactcaatta agccaatcga tgctctagga
    10321 actcgtacga ccatctcccc atattcttca agaatatcgc cagcgcctcc ttgaatgtat
    10381 ccctttaacg tttgtgtatg cctgctcggc aaagtggggc gctcagcaga gatgccgatg
    10441 tcataattca agagctcctc ttgtctttca atctgagatt cctgcgttat agatggctca
    10501 gatgatctgg cttcattaaa agattcactt aagctttctt ctggtatatt aaaagattca
    10561 cttgtgcttt cttctggtac attaaaagac tcacttgtgc tttcttctgg tacactgatt
    10621 tctattgaga ccgtatttga ttgaatatca ccgcttcttg cggtcaattc gtatttacct
    10681 gaatgctggg aagaataagt aatcagacgt tcgtaatcat tgagttgctt cacttcccct
    10741 tcaatcaaat cctcactctt atcaatgacc aatgcattta gcaggtctgg tgttcctctg
    10801 actcgcaact ggaactgctc acccaaagca gcctcctctt gatcaacttc gatcgtcagc
    10861 gaacgctctg gctgttctgc taaagactca gctagaaccg ttatgttccc aaattgattg
    10921 atcacaataa gcataactag aaacatactt aacagtttat gaaatttgtt cctcactatt
    10981 actccccctt ataattttga ctaaacaaca aggtacccga taattttcta aaaagattcc
    11041 ccaactcaaa atggctgcgt tacctccctc gtattttcgg ttcaactcaa gcgttgcaat
    11101 gtaagctgta aacaaagcta atgattgccg attgtcttct gttgattgat tcgatagctt
    11161 tgtatgactt ttagttgtcc gtgtggctta accataatta tgatttcacg attcctcctg
    11221 ccagtgcctt gcacaagctg gagcgtaacc ctaatagtta ttttgttaat gtacttatat
    11281 acttttatac ttttccatta gaaacaatca ctaaatcgtt gataccaagg tcagactcta
    11341 gaatttcatc agtgagtccc tgtattggtt aaccttcatc aatcccaaaa aaatatatca
    11401 atgcttagca tcaaaatgaa tatatagttt agaatacttg ggattcatcg ataactgatc
    11461 gcttatttgg ccatattatt tggcacttgg ttcaactaaa cgcatttagg atgttccttc
    11521 attctcgtca tggatgttct caaaccgtca ttactaataa actgtccacc gaatcgatgg
    11581 ttcatttctt gcattttcca cgtccaatta ctctttttgc tctttatttg ggcgtagttt
    11641 cactttctta acttgtatcg tcttccatca actccttaat catcttctta gctttattgg
    11701 ctcggtttcc ttgtaaaagg tatctacaaa tagtgacaat ctgtattaaa tcttcatcat
    11761 tttctgtaat gtcaataa
//
LOCUS       DADVXK010000087        11570 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.088, whole genome shotgun sequence.
ACCESSION   DADVXK010000087 DADVXK010000000
VERSION     DADVXK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.088"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(222..707)
                     /locus_tag="KB909_002189"
     CDS             complement(222..707)
                     /locus_tag="KB909_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBB6838190.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    797..1142
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1187..1828
                     /locus_tag="KB909_002190"
     CDS             1187..1828
                     /locus_tag="KB909_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6838191.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1847..2482
                     /locus_tag="KB909_002191"
     CDS             1847..2482
                     /locus_tag="KB909_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6838192.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2500..3315
                     /locus_tag="KB909_002192"
     CDS             2500..3315
                     /locus_tag="KB909_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6838193.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3634..5070
                     /locus_tag="KB909_002193"
     CDS             3634..5070
                     /locus_tag="KB909_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6838194.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5259..7691
                     /locus_tag="KB909_002194"
     CDS             5259..7691
                     /locus_tag="KB909_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6838195.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            7921..8988
                     /gene="rlmN"
                     /locus_tag="KB909_002195"
     CDS             7921..8988
                     /gene="rlmN"
                     /locus_tag="KB909_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6838196.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9181..10284)
                     /locus_tag="KB909_002196"
     CDS             complement(9181..10284)
                     /locus_tag="KB909_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6838197.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10836..11384
                     /gene="aac(6')"
                     /locus_tag="KB909_002197"
     CDS             10836..11384
                     /gene="aac(6')"
                     /locus_tag="KB909_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6838198.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3839 a         1951 c         2496 g         3284 t
ORIGIN      
        1 ttccgattta taatcgaaaa aagaagcatt tttatatatg cttctttttt cgtagaatca
       61 ataaatatgg atttggctaa ctatggaaga atactcgtat tagttttcag cgttcatact
      121 agttgttaca ttgtttgatt ggccaaaaga atttctgata tattttgtgc taaataaaga
      181 aaaagacgct tgaattggga aataagaaaa ctactctatc attacaaatt ttcataaact
      241 ggcagatgtt ctaagtaaac aagtatcttt tcaaagtcgg aaaaatccat aatcaacgta
      301 gtggtattga tatttggatg aaagcctacg gtatcttgac gatcaatagc agcatcgatc
      361 acgacttgga tttttttctc tttgtcgtgc atcaatgcta atggagtcac tgtacctgct
      421 ggaacgccta ggaggtcagg aagctgttct tcagaaacaa aagataagcg cttttctttt
      481 aattgttcag ctagttgttt taaatcggcg tgcttttcat caggcaagat gacaagatag
      541 atttgttttc cttttcttga tttcaataat agatttttta cttgcggacc aggtagggaa
      601 aaagggacat ttttgactga cgtaatcgca ggatgatcga ctttttgaaa agagataccc
      661 agttttttta gtagttcata agcttcttgt tcggttgcac gactcatcgc gcatcaccct
      721 ccttttttta ttagtgtatc ataaaaaaga gttgacaaat gaaaaataat catgtaaatt
      781 acacgtaaag ttaaaacaaa tgacatcgaa aagaagagta gccgttaggt gtttttagag
      841 agtctctggt tggtggaaag aggcagcagt taaccgtgaa acacatcttg gagtcgattt
      901 tctgaagcgt atagtaggaa aatccgggga gcccgttaca gctgcggtcg ttgctagatg
      961 accagataag gctggctttt ccgtgaggag tcggtaaaaa aaggtggaac cacgtgatta
     1021 acgtcctttg atcttcggat caaaggactt tttgttttca tctgaacggc aacgactgtg
     1081 tgaggttttt tctgcaagga aaaaataaac agaggtggaa ccacgtataa tacgtcctct
     1141 tggcatttgc caagaggatt tttttatttt aaaggaggaa aagaagatgg agtatttgat
     1201 tgaagttatg ccgcaattat tagtaggagc actcacaaca ttgaaattat ttttatttac
     1261 cttgattggc tcattaccat tagggattgt tttagcatta ggattgtctt tgcattttaa
     1321 gccgctacgc tacttgcttc aaacatatgt atgggttatg cggggaacac cgctgttgtt
     1381 gcaactgatt tttatttttt atgggttgcc gacgattggg atcgtttttg atcgtttcga
     1441 agcagcactc attgccttta tcttaaacta tgcagcttat tttgcagaga tctttcgtgg
     1501 agggatacaa tcgattcctc aaggtcaata tgaagcagcg caagttttgc aattaagtcc
     1561 ctttcaaacg gtgacgaaaa tcgtcatccc acaagtgaca aagattgttt taccttctgt
     1621 agggaatgaa gttatcaact tggtcaaaga ttcttccttg atctatatat taggtttagg
     1681 tgacgtaatg cgtgctggga aaatcgcgat ggaacgcgac gcgactttac tgcctttgct
     1741 aggcgtggca atcatctatc ttacattgac tggtattcta acaatcgtaa tgaaacaagt
     1801 tgaaggaaaa ttaaattatt accgctaact gataggagga agaaatatga ttgaattgaa
     1861 gaaagtgaac aaagcatttg gtgaaaaaaa aataatcaaa gatttgaatc taatcattcc
     1921 agatgggaaa acattagcta tcgtaggtcc ttccggtggc ggtaaaacca cgcttttacg
     1981 tatcttggct ggcttagaaa gttctgacag cggagaattt tatttagacg gtgtaccgtt
     2041 caacccattc gagcttaaaa tgaaagaaca agttgtagga gtcgtattcc aagacttcca
     2101 gctatttcca catctgaata tttttgaaaa cattacctta gcaccaaaaa tggtattgaa
     2161 acagacaaaa gaagaataca ccaaaaaagc agaagaatta gcggcttcat tagggattag
     2221 tgatttattg aatatctatc cttatcagct ttctggcgga caaaaacagc gggtagcgat
     2281 tgccagagca ttggctatga atccacgggt attggcttat gatgaaccaa caagtgcttt
     2341 agatcctgaa ttacgccagc aagtcgagcg tttgatccta tcattgaaag aagatggggt
     2401 aacccaaatt attgtcaccc atgatttagt atttgcagaa aatgtcggtg atcaattact
     2461 aaaagtttcc ccaattcatt aagaaaggag aagatagaga tgaaaaaaac cagttttcta
     2521 ttcgctttga tcgcaggtct tcttcttttt gcaggctgtt cgaacaaaaa aacttcagca
     2581 gataattggg cgactatcaa cgaagagaaa aaaatcgtta taggtttaga cgatacattt
     2641 gttcctatgg gatttagaga taaagacggg aagctcacag gatttgatat tgatttagcc
     2701 aaagcagtct ttgaacaata tgggattacg gtagactttc agcccattga ctggtcaatg
     2761 aaggaatttg aactgaacaa tggaacgatc gatttgatat ggaacggcta ttccaaaacg
     2821 ccggcaagag aaaagaaagt gcaatttaca aaaccttata tggaaaacga tcaagtgctg
     2881 atcacaccta aagaatcagg aatcacaaac tttggacaaa tgaataataa gagattaggt
     2941 gcgcaaaatg ggtcatctgg ttatgatgta tttacgaaac aaccagaagt attaaaagag
     3001 atagtcaaaa accaagatgc tgttttgtat gatagtttta atgaagcatt gatcgatctg
     3061 aaaagcagac gggtcgatgg tctgctgatg gataaagtat acgcagacta ttatttgaaa
     3121 caaagaaacg aactagaaga cttcaacata acaaaaggtt cttatgagag tgaggatttt
     3181 gcagttggtg cacgcaagtc agatagtaca ttagtgaaaa aaatcaatga agccctagat
     3241 caactagaga aaacaggtga attccaaaaa atatccgata aatggtttgg cgaagatgtt
     3301 acgccgagaa attaacaaat aggggactgt gacaaaagac gtgtcacagt ccctttttcc
     3361 gaataaacag tgttctcctg ccaactcctt gtgactcgga gctgaatggc aggctcacaa
     3421 cctcttggta aacggtgttc aaaagccagt ttttcggtat taagccaaat ttatgcaaaa
     3481 atgtagaaag ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac
     3541 aacctccttt acataatttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg
     3601 aacgattgaa ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt
     3661 ccaaaagatt ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa
     3721 gaagatggga aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt
     3781 aaaggaacga acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct
     3841 ttaatgaaag aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt
     3901 cctaatggac gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac
     3961 gaattgattg aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa
     4021 gcattgcaag atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat
     4081 tatgcagaaa cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat
     4141 gaacaaaata tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca
     4201 gacccgaaac gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc
     4261 aataaatttc acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca
     4321 aattatccaa ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg
     4381 atggccaatt attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg
     4441 ttcttagaag aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa
     4501 tctgctaaac cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat
     4561 ccattaaacg gagttggtgc tggaaaaatg aatacgacag gaaaaaaaag ttcatcagaa
     4621 gaaactggag ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat
     4681 tgggactggg agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt
     4741 taccgcatgc cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa
     4801 gataaacaaa tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc
     4861 aaagaagcaa tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat
     4921 ttgcttagct ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac
     4981 gaaacacaag aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa
     5041 ctgattgaag aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct
     5101 ggatatggcc gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata
     5161 agctgaaaaa tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt
     5221 ttttgtataa tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta
     5281 ctaaaaaaag gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc
     5341 tgacgattgg tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag
     5401 gttttttagg aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa
     5461 tcctctgtct tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt
     5521 caattggtaa aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat
     5581 tgttacatgc ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga
     5641 catgggattt gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg
     5701 ggatgattgg agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt
     5761 atttagcagc agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct
     5821 atcagctgtt aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg
     5881 atcctgccaa gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag
     5941 aagcgaaaga agcaaggcgc ttagctgcaa aagaagctgc agaatatgag aagaaaaaag
     6001 cggtgagcca gcaaagggaa aatactgctg atgaatggca ggaaccagaa aatacagagc
     6061 cggagcagct aagttttgtt ccaatcgaca gttttcaaga aaatatccat cctgcgaatc
     6121 tagagaaacc agtaccagat acaccaaaac agaccaatac agcagaaggt ttttcagatg
     6181 agttgccaga ggatgacggt acctcattag aatttgagat tgaagcagaa caggaaaatc
     6241 aagactatga attaccgaca gttgatttgc ttgattctat accaactgtg gatcaaagtg
     6301 atgagtataa aaaaattgaa aaaaatatcg gcgtattaga acaaactttc caaagtttcg
     6361 gtgtcgatgc caaggtcgtc aaagccagct taggaccatc cgtcacaaaa ttcgaagtcc
     6421 agccggctgt aggggtaaaa gtaagtaaaa ttgtgaactt aacagatgat atcgcgcttg
     6481 ctttagcggc gaaagatgtc cggatggaag caccgattcc aggtaaatca ctgattggta
     6541 ttgaagtacc aaatggaaag atcagtatgg tttcctttag agaaatcatc gaagcacaac
     6601 caaaccaccc agataaatta ctagaagtac ctttaggacg tgatgtttct ggacgggtac
     6661 aaacggctga tctttcgaag atgcctcact tactcgtggc tggttcgact ggtagtggga
     6721 agtcagtagc aattaatggg attatcacaa gtatattaat gcgtgctaag ccccatgaag
     6781 taaaactgat gatgatcgat ccgaaaatgg ttgaattgaa tatgtacaac ggcatacctc
     6841 atctgttgac gccggtcgtg acgaacccta gaaaagcagc gcaagcctta caaaaagtag
     6901 tacaagaaat ggaagaacga tatgaaaaat tcgcggcaac cggagtaaga aatatttctg
     6961 gttacaatga atttgttcaa cagaaaaact tggaaaacgg aacgaaacat ccaaccttac
     7021 cattcatcgt agtgatcgta gatgaattag ctgatttgat gatggtagcc agcaatgaag
     7081 ttgaagatgc gattattcgt ttagcgcaaa tggctcgggc agcggggatt catatgatcc
     7141 tagctactca acgtccaagt gtggatgtta tcacaggaat catcaaagca aatgtacctt
     7201 ccagaatggc atttgcggta tcaagcggta cagattctcg gacgatcatt gattctaatg
     7261 gggcagaaaa gctcttaggg cgaggagata tgctattctt gccaatgggt gagaataaac
     7321 cgatccgtgt gcaaggagca ttcatttctg accacgaagt agaacgggtc gttcaatttg
     7381 ttacagatca gcaagaagct cattatgaag agaaaatgat gccgacagat gaagttgaaa
     7441 cgacaggtgc tccagaacag ccacaagatg agctgtttga agaagcaaaa gcacttgtcg
     7501 ttgaaatgca aacggcaagt atttcccttc tccaaagaag atttcggatc ggttacaacc
     7561 gagcagcacg tttagtagat gaactggaag ctcatggagt tgttggcccg tcagaaggaa
     7621 gcaagcctcg gaaagtattc attgagcagg aagaaacatc agaaacgttg ccggacgata
     7681 atgacatgta aaacttgtgt gatgaagggt tgaaaaacga ataaccaata aaaagacaag
     7741 gcatgatgat accaaaagaa aaaatggttt ttttccatct tttctaatac ggtatgatgt
     7801 cttgtctttt tagtttttgt gagattaaag ttctattcga tttatttgtg aagtattgca
     7861 ttaaggaaat gaatcatgta tagtatgtag cgaaactttg agaaaaagag ggaaaatact
     7921 ttggaaaaac agtccattta tggcttgacg aatgaagaat taatcaattg gtttatagaa
     7981 aacggcgaga aaaaattccg agctgcccaa gtttgggaat ggttgtatca aaaacgtgta
     8041 agtaatttca cagaaatgac gaatctatcg aaacaattga tcgaaaaatt atcggagcat
     8101 tttatcatca atcctctaaa acagatggtc gtccaagaag cttcggatgg tacagtaaaa
     8161 tatttgtttg aactccctga taaaaacatg attgagactg tactgatgag acaagaatat
     8221 ggcttgtcag tttgtgtgac gacacaagta ggatgtaata tcggctgtac gttttgtgca
     8281 agcgggctgc tcaaaaagaa ccgtgatctg actgctggag aaattgttgc acagatcatg
     8341 atggtccaac attattttga tgagcgcaat cttggcgaac gcgtttcaca tgtcgttgta
     8401 atggggatcg gtgagccatt tgataattac gacaatgtaa tggacttttt gcatatcatc
     8461 aatgatgcca aaggattggc aattggtgct cggcacatta cagtttccac tagtggatta
     8521 gcacacaaaa tcaaggaatt cgctaataac ggcttgcaag tcaatctggc tatttccttg
     8581 cacgcgccga ataatgaggt gcgaacatcg atcatgcgga tcaaccgaag tttcccaatt
     8641 gagaaattga tggaagctgt ggatgagtat ttagagaaaa caaaccgtcg aatcacgttt
     8701 gaatatatca tgttgaatca agtaaatgat agaccagagc atgcgcaaca attagcagat
     8761 ctattaaaag ataagaaaaa attagcatat gtcaacttga ttccatataa tccagtcagt
     8821 gaacatgatc aatattctcg cagtccaaaa gctgatgtat tgagatttta tgatgtattg
     8881 aagaaaaacg gcgtaaactg tgtgatacgt aaagaacatg gtacagatat tgatgcagct
     8941 tgcggacaat tgcgaagcaa gcaaatgaaa aaaacagttg ccaaataatc gtatcctact
     9001 cgttttttca attaccataa aaggagcagt tttcttaatt aaggaactgt tcaacttaaa
     9061 taagagaaaa gattctatag cgaaagctat aaagcttttt ttgacaagaa aaaccctcat
     9121 caagcaaaga aatgtcctca atttgatgac agcctgcttg atgggggttt tagcaattat
     9181 ttaactgatt ttcttatatc cttgctggct ttcttgtgta gcatgataag tttctacgtc
     9241 aagaatggcc tgtttaaatt tttctcgggt gatttcataa ggcacatgtt taatatcatt
     9301 tgttgccatg gctttatcta agattgcttc taaatcggtc gtgacattga gattcatgtc
     9361 ggttaacgat actggaagtt ggttcttttt cataaacaca tagattttat caaacaaatc
     9421 gaactgctga tccatcatca ataaggtcag tacaccataa ctgacagatg ctccgtgaag
     9481 gtatccctcc attttttcta gaacagtcgt accgtaatag aatgagtgtg ccatagcaga
     9541 attatagtta ttgttaacta aaacagaaac caatccggta gtaacaatga tatccgaaac
     9601 gacttgttca attgcatatg agggacgatc gtcggcacta tctttcaatg cttgcgtacc
     9661 ataagtcaag agacgatcaa tgcacatttt tccgatttgg attcctaatc tatccgtgta
     9721 gcctagatca tcgccacgag cagaaaaagt agattcgact tctttggata aagcatcgcc
     9781 aatacctgcc cataagtatt tatcaggtgc ttcggcaata attgctgtat caatgaaggt
     9841 gtgtacaggt ggttttgaag gaaagaagag tccgtccatt acgccttctt cgttatagat
     9901 gacacatacc gcagtgacgg gcgaacagtt cgaaccaata gtgggaaagg tgaagactgg
     9961 tttagctagt ttttcaccaa tgacttttac agtatcgcaa gcacggccac caccgactgc
    10021 aaacaggacg tctgcttttt ggacactttc atgctggatc aactgttcaa tatttccata
    10081 agttgaatta cccccgtacc agagactggc gacaacctct atttcctgtg tcaaagctac
    10141 ttttattttg ttttctgcct ttgaaagtgc agtcttccct ccaatcagca ctacttttgt
    10201 cccatattct ttgacgattc catttgcttt ttcatacgca tctgttccaa tggtataatt
    10261 tggtaagaaa acactttgac tcatattcat ttccttcttt cttcgttgaa acgggttaaa
    10321 attttaaaga gtgatcgatc tgactgcggc tgtagatgga gtagaggtga acctaagaca
    10381 ggataagtga tgaataaggt ggcatgaaca ccttgaaatc atcaataagt atcctaaaaa
    10441 cgaacaagta caaaaacatt gaaaacgaca ataatgaatt tttgttcctc ttagtatttc
    10501 taccgattcc ctttgctttt ttgtaattat ctaaaaattc taaaaattaa gattattata
    10561 tgaaaacagg ttttatttgt caattcataa ttggtttttt ttaaagcaaa agataatcta
    10621 tatcatgatg aacaaacaga gttttttcct ccaattgatg gctttcctga tctttcctat
    10681 tttgaataaa gtgtttctgt ataatttttt attttataag taagataaat aatgaaagaa
    10741 tagagatact gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg
    10801 actgttagaa taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta
    10861 ataatccagt attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat
    10921 atggagacag ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag
    10981 cagcggtaga ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca
    11041 caggttggga attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta
    11101 ctcgattagt caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt
    11161 taggtacgga tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata
    11221 catttgataa agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa
    11281 aattaggtta taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata
    11341 tttggatggc aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga
    11401 cagaagtaat cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt
    11461 gtgaaattcc aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt
    11521 gaaaaagtcg cttagtttcg agtagtaaga aaaattttgt gaaaatggct
//
LOCUS       DADVXK010000088        11500 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.089, whole genome shotgun sequence.
ACCESSION   DADVXK010000088 DADVXK010000000
VERSION     DADVXK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.089"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            186..1847
                     /locus_tag="KB909_002198"
     CDS             186..1847
                     /locus_tag="KB909_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6838199.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1917..2279)
                     /locus_tag="KB909_002199"
     CDS             complement(1917..2279)
                     /locus_tag="KB909_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBB6838200.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2347..3288
                     /locus_tag="KB909_002200"
     CDS             2347..3288
                     /locus_tag="KB909_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838201.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3289..4332
                     /locus_tag="KB909_002201"
     CDS             3289..4332
                     /locus_tag="KB909_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838202.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4338..5408
                     /locus_tag="KB909_002202"
     CDS             4338..5408
                     /locus_tag="KB909_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838203.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5398..6351
                     /locus_tag="KB909_002203"
     CDS             5398..6351
                     /locus_tag="KB909_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838204.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6363..7373
                     /locus_tag="KB909_002204"
     CDS             6363..7373
                     /locus_tag="KB909_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838205.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7658..8479)
                     /locus_tag="KB909_002205"
     CDS             complement(7658..8479)
                     /locus_tag="KB909_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6838206.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8576..8854)
                     /locus_tag="KB909_002206"
     CDS             complement(8576..8854)
                     /locus_tag="KB909_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838207.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9122..11131
                     /gene="metG"
                     /locus_tag="KB909_002207"
     CDS             9122..11131
                     /gene="metG"
                     /locus_tag="KB909_002207"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBB6838208.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
BASE COUNT         3837 a         2088 c         2324 g         3251 t
ORIGIN      
        1 agaccatgga aaaccttgta caaagctatt ttttctgaaa aattccttga aacctcacga
       61 aaaaatcatt attttatgaa aaagacaaaa aaaagtgttg attttttaat aattattcat
      121 taaactctta aacaacttca gaaaatatta attattctga aaattccaat aaaggggtac
      181 gtaaaatgaa aaagaaattt acatttggtt tggttgcggt atgcggcctt gtacttgctg
      241 gatgttatgg cggcagttca gccacaagca gtagttcagc aaaaagcggt tcagcagatg
      301 gaggaggcgt atttaactta gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg
      361 caacagatac aatcagtttt acagcattga ataacgttta tgaaggaatt taccgtcttg
      421 atgaagacag caaaccacag ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg
      481 gattaactta caaaatcaaa ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta
      541 cagcagcgga ttacgtttat ggctggcaac gaacagtaga cccagctaca gcttctgaat
      601 atgcttacct gtatgcgcca gttgaaaatg cagaagacat tacagctgga aagaaagata
      661 aatcagaact agggatcaaa gcagttggtg actatgaatt agaaatcaaa ttgacgaaac
      721 aaacaccata tttccaatat ctgcttgctt tcccatcatt tttcccacaa aaacaatccg
      781 tagtggaaga aaatggggat gcctatgcat ctgcaagtga taaagctgtt tataatggac
      841 cattcacatt agaagatttt gatggaccag gaacagatac agaatggact tataagaaaa
      901 atgatcatta ctgggacaaa gatacagtaa aactttctga aatcaaagtc agtgtagtaa
      961 aagaatcttc tactgcattg aacttattca aagatggcca agcagatgac gtgatcttgt
     1021 ctggtgagtt agcacagcaa aacgcaaacg atccagctta tacttctgtt aaagaagcgc
     1081 ggacaagcta tatcgaattc aatcaacgtg aaaagaattc accattcaac aatgtgaacc
     1141 taagaaaagc tatttcttat tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg
     1201 acggatcagt tgtctctaca ggattgatcc catcagatat ggtaaaaagt ccaacaacga
     1261 acgaagactt tgcaaaagaa gctggaaaat tagtttctta tgacaaagat aaagcaaaag
     1321 aatattggga aaaagcgaaa aaagaattgg gcgttgattc tttagaattt gatttgatgg
     1381 cttctgatga tgattcatcg aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa
     1441 acttggatgg cgtaacagtc aaaccaacac ctgttccatt ctctgtacgt cttgaccgct
     1501 caacttcggg tgattttgac gcagtactag gcggatgggc tgctgactat gcagacccaa
     1561 gcagctttac tgatttgttt gtcacaggta attcatacaa ccgtggtcgc tggagcaatg
     1621 cagaatatga cgaagcagtt aaagcagctt catcaacaga cgctggcgat gaacaagccc
     1681 gttgggatga tttccaaaaa gcaatcaaga tcatctctga tgatatgggt gtcgttccgg
     1741 tgtaccaaaa agcagaaggt cacctagtga atgaaaaaat caaaggtatc gttcaccatg
     1801 cggcaggcgc ttcatgggat tacaaatgga catacgttga agaataatcg ttaataccgt
     1861 gagcatgaga aaaaacgagg ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat
     1921 cctaacaaag aaaaaagcat gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc
     1981 agccaaaagc tgtacatacc gtagctggca gacgagagcg tggaaaattc tggttttttc
     2041 tttcggttcc ttgttcgtgc aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa
     2101 gaaaagaccc ataaaaaacc gccgataatc agaaacggca atgaccataa gaatagatca
     2161 ttagataatt gaatgagtgt aaaggaatgg ttgatgagat tttttattaa aataaccaga
     2221 atcagtagaa aagctactgc gtaggggata gatttttttt catttgattg ctcctttatt
     2281 tttggttcat tatctaataa tgtagcgaaa catctgtcag aagtcaaaag ctagggggaa
     2341 acattagtga atagttatat caaatatgta ttaaaacgtg tctttttcat gatcatcacg
     2401 ctttggttaa ttgcaacaat cacctttttc ttgatgcaat tgctgccggg cacgccatat
     2461 acgaatcagg aacgtttgag tcctgaaaca atcgagatgc taaataaaca agtcggtttg
     2521 gataaaccag ttatcgtaca atatgggatt tatctttcta atttgcttca aggagatttt
     2581 ggaatttcct tccaatttaa aaaccagcca gtcgcacatt tgttagctgg aagaatcgga
     2641 ccatccttgc agttagggtt acaggcaatt atctttggaa cagtcctagg gacgatttta
     2701 ggaacgatct ctgccatgaa gcaaaataca tgggcagata catcttctac actcgtagcg
     2761 atattaggtc gttccattcc aaactttgta tttgctgttt tattacaata tatctttgca
     2821 atcaaattac aagttttgcc aatcgcaaaa tgggatggct ttgtgtacac aatcttacca
     2881 acaattgcgt tggccatgtc gccgcttgct gactctgctc ggtttatccg tacggaaatg
     2941 gtggaagtac tgcatagtga ttatgtggaa ttagcaaaag caaaaggatt gagccgttgg
     3001 gaaatcgcct ttaaacatgg tcttcgaaat agtttgattc cattgatgac tttattagga
     3061 ccgttagctg tagcattgat gaccggatca ctggtggtag aaaatatctt tgctattcct
     3121 ggtatcgggg aacaattcgt taagtcaatc acaacaaatg attatcctac gatcatggct
     3181 gtaacgatcc tttactcatt tatgctgatt tttgttattt tgatcgtgga tctattgtac
     3241 ggtctagttg atccaagaat tcgtgtttca gaagggagcc gaggataaat ggaaatgata
     3301 ccaaagcgtt atgaaacagt tgcagatatc cctgcggatg aatttcttcc attacaaaaa
     3361 aataccgaag aagaacgtga acagattact gcaccttctt tgaattttat ccaagattca
     3421 tggcgccgtt taaagaaaaa caaagctgcc gttatttcaa tggttttact attggtcatc
     3481 attttgatct ctgtgatcac aatctttgtt tctcctcatg atccaactgc ccaaaacgtg
     3541 gcttatatca atttgcctcc tcgtattccg ggaatcaata tcgatggatt gaatggaaaa
     3601 gcaatggttg gtggtgaact tgttgataaa tatgctcaag caaacgtccc ttcaaacgta
     3661 aatttctttt taggaacaga cggtttggga cgtgatgtat taagccgctt atttatggga
     3721 atgagaatct cgttgctgat cgcatttatt gctgcattac tagatgtaac gattggtgta
     3781 gcttacgggt tggtttctgg tttgttaggc ggacgtgtcg ataacgtgat gcaacgtttt
     3841 ttggaaatct tatcaggaat tccaaacctc gttgtcatga ttttgatgtt ggtcgttttt
     3901 gaaccaggaa ttttttcaat cgtggctgct atggccatca caaactggat accaatggca
     3961 cgtatcgttc gtgcacaaac aatgaaatta aaagatcaag aatatgtttt agctggattg
     4021 acattaggtg aatcaagaat gaaaattgca ttcaaacata ttttgccgaa tatctctagt
     4081 gtcattatta ttcaaatgat gtttagtatt ccatctgcta ttttcttcga agccttttta
     4141 agctttatcg gtttaggtct tacgcctccg tcagcttcat taggaacgat gttgagcgaa
     4201 gggtacaaga cattcctgta tctgccttat ctattatgga ttccggcagt aactttatcg
     4261 gttatcatga ttggctttaa cttacttgct gatggattgc gtgatgcctt tgatcctaaa
     4321 atgaaagagt gaagacgatg acgaaaattt tagaagtgaa agacttagaa atctcttttg
     4381 atacgtatgc tggaaaggta cgagcgattc gcggtgtcaa ttttcatttg aataaaggag
     4441 aaacattggc gatcgttggg gaatctggaa gtggaaaatc agtgacgacc agaagcatca
     4501 tgcgcttgct gtcaagcaac gccaatatag atgctggtca aatcctcttt aaaggtaacg
     4561 atatcgttgg aaaatcagaa agagagatgc aaaaaatccg tggtaaagaa atagcgatga
     4621 ttttccaaga tccaatgacc tctttagatc cgacgatgcc cattgggaag caagtcgctg
     4681 agtcccttag aaagcataat aaagtttcaa aaaaagaggg acaaaaagct gcattagaat
     4741 tgcttaaatt agttggaata cccgaagctg agaaacgtat caacagttat ccgcatcagt
     4801 tctcaggagg tcagcgtcaa cggatcgtga tcgcgattgc actggtatgt tatccggaaa
     4861 tcctgattgc tgatgaacct acaacagcgc ttgatgtgac tattcaagca cagattttgg
     4921 agctgctgaa agaaattcag acaaaaatcg atacatcaat tatctttatc actcatgacc
     4981 ttggtgtagt agcgaatgtc gctgatcgtg tcgctgtcat gtatggagga agaatcgttg
     5041 aagttggaac atcggaagaa attttctaca acccgcaaca tccctatact tggggactgc
     5101 ttggttcaat gccgacatta gatagtgcga acgatcgatt gtatgctatt cctggttctc
     5161 caccggattt attgaacccg ccaaaaggag acgcattcta tccaagaaat gaattcgcga
     5221 tgaaaatcga tgcagaacaa gaaccaccat tttttgaact atcaaaaaca cacaaggcag
     5281 caacttggct acttgctccg caggcaccca aagtgacacc gccagaagaa atccaacgtc
     5341 gctgggctat ctttaaagag aaacaaaaac atacttacgg tcaaggagga attgctgatg
     5401 ccaaataaac tacttgaagt taaaggattg aaacagtatt tcaatgtagg aaaaaagaat
     5461 gaagtacatg ctgtaaatga catcagcttt cacatttatg aaggagaaac attcggttta
     5521 gttggagaat ctggaagcgg aaaatccact actggccgta cgatcattcg cttgaatgaa
     5581 cctactgatg gtgagatatt attcgacggt caagatataa cgaagatcaa agataaaaaa
     5641 ggtttgacga aattccggca tgatgttcag atgatctttc aagatccata cgcttcgttg
     5701 aatcctcgta tgaaagtcag agatatcatt gccgaaggaa ttgatgttaa tggactagct
     5761 aaatcatctg aagagcgtgc aaaaaaagtc gatgatctat tgagaactgt tggattgaat
     5821 ccaagccacg gtactcgtta tcctcatgaa ttttcaggtg ggcaacgcca gcgtattggt
     5881 attgcacgag cattggcagt aaaaccgcgt tttatcattt gtgatgaacc aatttctgca
     5941 ctagatgtgt cgatccaagc ccaagtggtc aatttgttgc aagatctcca aaaagaacat
     6001 caattgacct atctatttat tgcacatgat ttgtcgatgg ttaaacatat tagtgaccga
     6061 atcggtgtaa tgcataacgg cttgttatta gagatgggaa caagtgatga aatctataat
     6121 cacggtgttc atccttatac agaaagtttg ttatctgcta ttcctctacc agatccagac
     6181 catgagagaa aacgcagaag aatcaaatat caacctgaac cagatgacgg acaagtacgt
     6241 caacttcgtg aaatcgcacc agaacatttt gtctatgcaa ctgagcagga agtcccatat
     6301 tacgcaaaaa aactaaaacg acaaaaggaa tctcttctgg ttgctaacta ggagggacat
     6361 agatgctaaa agcttttaaa ttccgtatgt atccgacaga agaacaaaaa cagcaattga
     6421 ttcgtacttt tggatgtgct cgatttacct ataaccattt gctgaaaaag cggcagaaaa
     6481 gttggcaaca aacaggagta gccaattttt cgctcacacc cgctacatta aaaaaagaat
     6541 acccattctt aaaagaagta gacagtcttg ctttagcaaa tgcacagctt aatttggatc
     6601 gggcttttcg caattatttc aagggacgtg ccagcttccc aaagcttaaa acgaaaaaaa
     6661 gtatgtggca atcttatacg accaacaacc aaacccgtac gatctatctg gaaaatggct
     6721 acttaaagtt accaaaacaa aaagaactaa tcaagataaa tcagcatcgg ccagttgaag
     6781 gatcgattcg ctccgctacg atttctgctc gatataatga agaattttat gtcgcactac
     6841 tttgtgatgt ttcgccagta aaaaaagaat ctttagctaa atggatcggg atcgcctatc
     6901 atccgaagac attgatccaa acatctcgac ctctagaagt aactttacca aaatttcacc
     6961 agacagaaga aaagctgcaa catgcacagc ggaaattgaa tgtgaaagtc cgctccgctc
     7021 accatagaaa gatcaggtta gatcaggcaa gcaattatca gaaacaaaag agaaaagtaa
     7081 tggatcttta tctgaaacaa aagaaccagc gagaagatta tcttgaacaa ttatctggga
     7141 aattggtcaa acaatatgac tacttatttg tagaatcttt tccaaaagaa gaggcacatg
     7201 ctgatttttc tattcacgac tggcataaat taataacaaa attgcgttat aagtcccaat
     7261 ggtataataa aaaatttctt ttgatcaata ccgacggagc agaagaaagc aattccgtaa
     7321 gaaagagcca agtagtagaa aaaatgggca gacattcggt tatcaaggga taaaaaatga
     7381 atgaaactga taggagcgtt agggttagcc ttgttaataa aaagtcttaa tgacttttgt
     7441 ttctaggaat ttttcttttg aagaaaagct cactaattat gacaaaccaa taaaacaata
     7501 gcagaaaaag ttcgtacgag ctttttctgc tattgttaat tttttattca gaaagtttac
     7561 gaatacatca aaattctgaa acaaaaaacg taactcacaa agagttgttt ttgcgttttt
     7621 tcttgaatga ttaggtctga atcttttgct cacaacctta ttcatggtgc cccggcttga
     7681 gctgatagat ttttgaagga cggccgattc ctacaggacg ttcaccgatc tcatcgaaat
     7741 attggagcat agctttctta aaattggaat gatcgatcgt tttataatcg atccctaaga
     7801 atttagcaaa tacttttcga gcttccgtaa tcgtgaaatc tttacctaaa acttgtagaa
     7861 cttgcggctc gtgttccatt ttattgacta cacggttgaa tgctttcaag atgatttgac
     7921 tatggtcaaa agccaaagta tctttgccag aagactctcc agtgactaaa tcaagcgaga
     7981 tagccacttc tccgctagat aaatggatct tgttactatg acgttctagt gtgaaccagc
     8041 gtacttcctt ggcatcatct ccggcgatta gcggttcttc tccaataaag gctaagtagc
     8101 tgactgtgac gacccagcct cgcggatctc gattaggcgt actgaatgta tgcagttgct
     8161 caatattttc ttttgaaata accacaccag tttcttcctt tgtttctctt aagacgcttt
     8221 ctccagttga ctcatccttt tggacaaagc caccaggcaa tgcccatgaa tttcgataag
     8281 gatgcccttt tctttggatc aacaaaactt tcagctgatc ttcttctttg ttatagcaca
     8341 tcagtacgat atcgacagtc aaagagggct tgtcatattc tggacgttcc tgtttttgat
     8401 accagttaag aaattcttct tcacttgctt tatgttcata atataatttt tcttcttctt
     8461 tagaagcaaa acggttcatc tgaccacctc cattgacagt aaaagtactt tttaccttat
     8521 tgtagcagac tctgaaaaaa aaccaaggat ttacttgaaa aatctaggtt atcatttaaa
     8581 tatgaaaaat aaatggaagt atgagattga ataaaaagaa aagcagataa aacggcaata
     8641 ctttataccg ctcttcacga atggcaaaga agccacaaat aacgatatat acgtcaatga
     8701 taaaacgcaa aatccaagct gctgtcataa aactgttcaa atgcccatgg aggttaaaat
     8761 aaccatacat acgaatataa aaatagctga atattaaatg tgctaatgaa agaaaagcaa
     8821 tactaagtgt aaaaaaaaga tgtttcttct gcatgattgt tccagtccct tactaagata
     8881 gatagtcttt attataccac gtgtgagggg agaaataaaa agccgttttt tagtagatat
     8941 gaaacaaaac aaaaacccgc atttattcaa cctattcatc cttttaaagg atagattgaa
     9001 cgtagataga agtcgtttat ccagtctttt tcattttgaa aaaaagctaa cagcatgctt
     9061 tttttatggt atactagcaa ggaaacgaat tcgcatcatg cgataaagga ggaagagccc
     9121 cgtggcagaa aaggaaactt tttatatcac tacgccaatc tattatccaa gcggcaaact
     9181 tcatatcggc aactcgtata ctacgattgc atgtgacgca attgctcgtt ataaacggtt
     9241 gatgggcttt gatgtgtttt atctcactgg agtggatgaa catggtcaaa aaatcgaaac
     9301 aaaagcagaa gaactaggtg taaaaccgca agaatatgta gataaaatgg cggctgatgt
     9361 caagaaatta tggaaaacgc ttgatatcag ttatgataaa ttcattcgca cgacagatga
     9421 ttaccataaa gcagctgttc aaaaaatatt tgatcgttta ttagaacagg gagatattta
     9481 cttaggtgaa tatgaaggct ggtactctgt ttctgacgaa gaattcttta cagaaacaca
     9541 acttgcagaa gtgtacaaag atgacgaagg taacgtgatc ggtggtaaag cgccaagtgg
     9601 acacgaagta gaattggtaa aagaagaatc atacttcttc cgcatgagca aatacgcaga
     9661 ccgtctattg gaatactatg aagaacatcc cgaattcatc cagccagaat ctcgtaaaaa
     9721 cgaaatgatc aacaacttta tcaaaccagg attagaggat cttgcagttt cacgaacaac
     9781 ttttacttgg ggagtaccag tcaagagtga tccgaaacat gtggtgtatg tatggatcga
     9841 tgcattatcc aattatatta ctgcactagg atatggctcc gaagatgaaa gtctattcga
     9901 aaaatactgg cctgcagatg ttcagatggt cggtaaagaa atcgttcgct ttcatacgat
     9961 ctattggcca atcatgctga tggcccttga tttgcctcta cctaaaaaag tatttgggca
    10021 tggctggcta ttgatgaaag acggaaaaat gtctaaatca aaaggaaatg tcgtttatcc
    10081 tgaaatgctt gtggaacgtt atggtttaga tgcactccgt tattatttgc ttcgtgctgt
    10141 tccgtttggg tcagatggtg tctttacgcc agaagatttt gtttcccgtg tcaattatga
    10201 tctggcaaat gatctaggga acttattgaa tcgaacgatt gctatgatca acaaatattg
    10261 tgatggactc gttcctgact atgcctcact tgtcactcca tttgatagtg aactgtctac
    10321 gacggctgct aacgttgtcg gacgttacca tgatgcaatg gaaaaaatgg aattcaatac
    10381 agcattggct gaaatctggg tgctgatttc tcgtgcaaac aaatacattg atgaaacaga
    10441 accatgggta ttagcaaaag acgaagaaaa gaaagctgaa ttgaatagtg tcatgatcca
    10501 tttagctgaa tctttgcgta tcgcagcgat attacttcag ccaatcatga cagaaacgcc
    10561 agagaagatc ttcaatcaac taggattgga ctctgaaaca atgaatcttg aaggattaca
    10621 ctttggcgaa tttccttcag gaacaaaagt agttgcaaaa ggtacaccaa tcttcccacg
    10681 tttagatatg gaagaagaag ttgcttttat tcaagaaaaa atgtctgaag gtactcaaac
    10741 aaacgaagat acagtcaaat gggatccaga agaaacagaa cttgtttcaa cgaaagaaaa
    10801 acaaatcaaa tttgatgtat ttgaaaaagt agaactaaaa gtagcagaag tcatcaactg
    10861 tcaaaaagta gaaggggcag ataagttgct gcaattccga ctagatgctg gagacagcca
    10921 agaccgtcaa atcttgtcag gaatcgctga attttatcct gatccaagcg aattgatcgg
    10981 gaaaaaagtc gtcattgtag caaatctgaa accacgaaag atgcgtggac aaatcagtca
    11041 aggaatgatc ctttctgcag aagcaccaga tggctcttta caagtaatcg aagcaccaaa
    11101 atccatgcca aatggctcag aaatcgcata gaaattcaaa gggggtatga cactagttgt
    11161 gtcatacccc ctttttccga aatttgagaa gcaattttcg taaattcctt cttattactt
    11221 gaagccaatc atataataca gaaacagaga actatccaaa ataaatccta gaaaaagaag
    11281 tacgagcttc gctgattttt gttaatttag aataatacta ataggaatcg taaaaacaga
    11341 aaaaaagcat aatgataaag ggtcgggcag attttaattg attcatctgg tactcttttt
    11401 tattgtcctt acattcataa agtttgaatg caatgacttt attacatcta tatttatatc
    11461 taacagtagc gttgatgtgt taattataag ttctatcact
//
LOCUS       DADVXK010000089        11445 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.090, whole genome shotgun sequence.
ACCESSION   DADVXK010000089 DADVXK010000000
VERSION     DADVXK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.090"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..222)
                     /locus_tag="KB909_002208"
     CDS             complement(<1..222)
                     /locus_tag="KB909_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838209.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKL"
     gene            516..1331
                     /gene="thiD"
                     /locus_tag="KB909_002209"
     CDS             516..1331
                     /gene="thiD"
                     /locus_tag="KB909_002209"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBB6838210.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1660..3111)
                     /gene="cls"
                     /locus_tag="KB909_002210"
     CDS             complement(1660..3111)
                     /gene="cls"
                     /locus_tag="KB909_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6838211.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3452..6118
                     /locus_tag="KB909_002211"
     CDS             3452..6118
                     /locus_tag="KB909_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6838212.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6482..7234
                     /locus_tag="KB909_002212"
     CDS             6482..7234
                     /locus_tag="KB909_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6838213.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7256..8410)
                     /locus_tag="KB909_002213"
     CDS             complement(7256..8410)
                     /locus_tag="KB909_002213"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBB6838214.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8595..11036
                     /locus_tag="KB909_002214"
     CDS             8595..11036
                     /locus_tag="KB909_002214"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBB6838215.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11193..>11445)
                     /locus_tag="KB909_002215"
     CDS             complement(11193..>11445)
                     /locus_tag="KB909_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838216.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3697 a         2025 c         2435 g         3288 t
ORIGIN      
        1 cagttttttc atctgtttat gaaattcttt tttttcagta aacataaagg tttgggtatc
       61 gtaaccttct tcatgtagga aatagattat tcctttttct gtgttttgcg tataagcttt
      121 tatactcctg tcttttttga aagaacagat cgtatagcca tctatttggt ctggtagtcg
      181 tttgattttc ttcaaaatga cttttttatc ctcaagtttc atttttttca cctgacttta
      241 tttttttcat atggaaatca tagcgccttt ggttatatga aaacaagaag gatactgaaa
      301 tatatataaa tcaaatagtg gttatttatt attagaatag cgaatacaaa taaacgacca
      361 ctattttctg atttattgca aatgtttttt caaataaatt tgattaccaa gaaaaggtag
      421 tggtatattt actgagggat actttgaaaa acatatgata gaaacagtaa cagtattatg
      481 aaaaatcttt ttataaaaat ggaggaatcg atttgatgga agatcagtat gtacaagcaa
      541 tgacgatcgc aggatcagat agcgatggaa gcgcagggat gcaagcagat atgcatacat
      601 tctttacaag aaatgtttac ggtgtttctg tcatgaccgc atgtgttgca ggtaattctt
      661 acggaatcgg agcaagtgtg acattgccaa cagattttat cgacaaagaa tttgaactga
      721 ttgcgaagga ctttcaaata cgtgcagcta aaacaggtat gctagcagat tcaaagttga
      781 ttgagacagt tgtaaaaaat taccaaaaat atgattttgg accattagtc gtggatcccg
      841 taatcgtaac gaaacatgga aatcttttac tagaagaatc tgctttgcaa agcttgaaag
      901 aaaagcttgt ccctttggcc gaagtactga cacctaattt ttatgaagca gaaaagctga
      961 ctggacggac attagcagct gaagaagatt ttgtgcaagc agcaaaagaa ctgcaagata
     1021 tgggtgcaaa aaacgttatg atcaaaggac atcatgctaa aaatgcgcag caagaaacag
     1081 tcaatgacta cgtattgttc gaatcaggaa aatcattttg gttaaatgca ccattttatc
     1141 ctaccgaccg gatcaacgga actggcgatt cgctatctgc atgtattgca gctgagttag
     1201 cgaaaggaaa aacagttgaa caagcgatcc gattggcaaa agactatgta aaccgtgcaa
     1261 ttcgtgaaga aataaatgta gggcacaaat atggccccat caatcattgg gcagctggtg
     1321 aattagagta aaagaaagaa gttgtgaaaa agttgccctg catcaagtaa taagaacagc
     1381 caagtaaaaa cagcttctta tgtttttaac ttggttggac ttattaccgc agatgcaagc
     1441 ttttgaacac cgtttaagaa agaggtcgtg agcctgccgt ccagctccga gtcacaagga
     1501 acaagttcaa aaaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaggagtt
     1561 ggcaggagaa caccgtttgt tcggaagaag ggactgtgac aagatttttg tcacagtccc
     1621 tttaatctta gtatattttt ctctacttga ataaaaaaat tataggattg gagaaaataa
     1681 tcgagaaatt tgttgcttga ataatagcca gttagacatt tccttgactg tttcagttgt
     1741 catggatgaa caatgtgtct catcttcttt gaactgagta gcaagttctt ctaaaaactc
     1801 aggatcgtaa atgacagcac ttgtttcaaa attcaatcgg tagctacgaa tatcttgatt
     1861 tgctgaacct accatgcaga tttcatcatc cattatcaat gtttttgcat ggaggaagcc
     1921 gttctcatag acaaggattt gtacattttc cttgatcagc tgccgagcat aatattgtgt
     1981 tgctcgataa ataaaaggat gatccggttt gttgggaatc atgattttca catctacacc
     2041 agaggcagtt gcgattttta aagcagcaat gacactttca tcaggaacaa ggtaaggtgt
     2101 ctgtatccaa acacgttttt tagcagaagt aatcaatttg ataaatgaaa gcttgatttg
     2161 ttccctttcg ttattcggtc cgcttgaaac aagctggatg gatgtatcag caagcttaga
     2221 ttcatctcga tctgcttttt taaagaaata attcaaatga tagccgacct ttttttcttc
     2281 aggtaccgag acgttccagt ctgttaagaa gcgaagctgg agcaaagaag aagcggcacc
     2341 gaaaatccgt atatgcgtat cgcgccaata gccgaatttt tttgttgtat ttacatattg
     2401 attggcaata ttgaaaccac cggtataact aatctttcca tcgatcacaa cgatttttcg
     2461 gtgatcatgg taattcaatc ggaaacgaag taatgccctt tgtgaggtaa caaatgtatg
     2521 gacatgtcca ccatttttga ttagacgatt gaaatctttt gcttttgtgc catgagagcc
     2581 aaatgcatca tataatattc gaacttccac gccttctgcg gctttttctt ctaaaacatg
     2641 taagacttgc tggccgatat tatctgtcac aaatgcgtaa tattcgatat ggatcgaatg
     2701 tttggctttt tttagatctt gaagcagtga atccaatttc tcttgtccgt ctgtgagaag
     2761 agtgacagaa ttcattcttg tcagcggcat acgatttaat gaagagaaga agtcaacaaa
     2821 ttgctgtttg tctttatcgc ccatgtcagg atcgtaatgt tcaatggtat ctcctctaaa
     2881 agactgaaag ttttctaatt ctttcaagtc actttgtcgg agatagaatt ttttcttatc
     2941 cgttaatcca cgtccgaaaa ataaatataa tacaaagccc accccaggaa gggcaaacaa
     3001 tactaagagc catgcccaaa tggctgctac atctcggggt ttgatcaaaa tagccaccaa
     3061 agcaataagt gcatttaata gataaagggc ggttataata ctagatacca caaaaatgtt
     3121 cctccttaca tacaataaca ttagtatagc atgatagaag aaagaagcct accaaggtga
     3181 atatactttt cactcctttc atgaaaatgt aggtaaatcg ggctaaagta gttgcttttt
     3241 gtaggttaat aaggtaggat attagtacag ttgaatatct ccttagggga gtaaccggca
     3301 acgtttgttg cgataatatc aacagtaagt taaccaaatg gttttctggt attgtatgaa
     3361 atggtgagac ctaagacaaa tgcgtatttg tcttaggtct cttttttttc agacaggact
     3421 agggccaaga tcaaaaaatg ggggatgaaa tttggaaaac aaggaacaag cacaacaagc
     3481 ggtctataaa gaaacgatcg actcgttgat gcagcaaacg cagagctcaa ccgatggatt
     3541 gagcaccacg caagcgaagg aaaaattaga aagagatggc ttgaaccagc taaaagaaaa
     3601 gccgaagaag ccaacttgga aattgttctt agaaactttc aaagatgcaa tggttatcgt
     3661 attgctgatt gtcgcactga ttcagatggt catgggtgac tacatcgaat tcttagttat
     3721 ttttgcagta ttgatgttga attctataat cagtgttgtc caaacaaaaa aagcagaagg
     3781 ttctttagaa gcgttgaaaa acctttcagc gcccgatgct cgagtgattc gtgatggtaa
     3841 ggaaaaaacg attccggcaa acgaacttgt ggtaggagat atcgtgttgt tagacgcagg
     3901 cgattatgta cctgctgatg gacgtttact agatgcggga tcattaaaag tagatgaagg
     3961 tatgctgaca ggagagtcga cttctgcaga aaaagaagta acggatatca caagtacggt
     4021 accaatcgga gatcgtacaa atatggtatt cagtggaacg atcgtaactt acggacgcgg
     4081 taaattctta gtgacttcaa ctgggaataa tacggagatc ggacaagttg ctggcctttt
     4141 ggaatcaaca actgagcaag tcactccgtt acaacgaggt ctggataaat tcagtaaaaa
     4201 actaagtttg gctattttgg cattgtcttt attgatttta ggtatccaac tgtttcgtat
     4261 ttatcttgga gaaggtacag gagatatgac tgcagatatc gtcagcgcag tgatgtttgc
     4321 cgtagccgta gccgtagctg ctattccaga agcattacag tctatcgtaa caatcgtgtt
     4381 atctttggga acgaataaaa tggcaaaacg tcatgccatt attcggaagc ttccagcagt
     4441 tgaaacactt ggttcgacaa gtatcatctg tacagataag actggtacat tgacacaaaa
     4501 caaaatgaca gttgttgact actttttagg taatggcgat actggggatt tcacaaatga
     4561 cccttcaaaa tggacagctg acgaacgtcg cttgatcgaa atcagtgttt tagcgaatga
     4621 tgcatcgatc agtgaagacg gtactaaatt gggcgaccct acggaagtag cgtttatcga
     4681 ctttagtgaa aaattaaacc agccttatca ggaaatccga aacaactacc caagacaagc
     4741 agaacttcct tttgactcag atcgaaaatt aatgtctact ggacacacaa ttgataacaa
     4801 aaattacttg tttgttaaag gcggaccaga tatcgtcttc caacgcagta aaaaagtatt
     4861 gctaaatggt gaagtcgttc cgatgacgga tgaattgatg aaaaaattcc aagagcaaaa
     4921 tgaagctttt tcaacacgcg cattacgtgt actagctttt gcttaccgtc cacttgataa
     4981 ttttgattta tcatttgaag atgaagacga tttgatcctt gttggtttgc ttgctatgat
     5041 cgatcctcca cgtgctgaag tgactcaggc ggtaacagaa gcaagaagtg caggaatcaa
     5101 aacaatcatg attactggtg accacaaaac aacagctgtt gctatcgcaa aacaaatcgg
     5161 gatttttgaa gaaggaaacc tggctttgac cgggacggaa ctagatgaat tgacagaaga
     5221 tcaactaaac gaagttttag aaaaagtcac tgtttatgca cgtgtttcac ctgagaataa
     5281 aattcgtatc gttcgtgctt ggcaaaataa aggtcatatc tcagctatga caggtgatgg
     5341 tgtaaatgac gcaccagcat tgaaacaagc agacatcgga attgctatgg gaacgggtac
     5401 agatgtggca aaagatgcag cagcgatggt attgacggat gataactttg cttctattgt
     5461 cagcgcagta gaagtaggac gtaatgtgtt tgataatatc aagaaagcta tttcttatct
     5521 atttgcagga aatttaggtg cgatcattgc gatcatcttt gccttagttg ctgactggtc
     5581 caatccattt acagcattac aactgttgtt catcaattta gtcaatgatt cactgccagc
     5641 aattgcatta ggtacagaaa aagctgaacc tgctacgatg aaccgcccgc caagagatcc
     5701 aaattcagga atctttacgg acaaaacatt gatttctgta acgtatcgtg gtgtgctgat
     5761 tgggattgct gttatctttg ctcaatggct tggcatgcag cattcacctg aattcggtgt
     5821 agccatgtca ttttcaacat tgatttggtg tcggacattg caaacattcc cagcacgttc
     5881 aaacacacaa acagctatcc aagcagggtt cttctctaac agaagtgtct tactagctgt
     5941 agttgtatgt agcgcgcttt actgcttaac aatgatccca ggactgaaag aagtcttctc
     6001 tatcccatca gcatttggat tgacagaagt ctttacatgt atgggaatcg cacttgtgac
     6061 aattgttttg atggaaatca ctaaattgat cattgtacga gtacaaggaa ataaataaaa
     6121 cgaatcaacg aggttgtgag cctgccgttt aattctgagt cacaaggtgc aatttcaaca
     6181 aacagcttct catgtttgtt gaatattgtg acttgtgacc gaagagttgg caggagaaca
     6241 ccgtttaagg aagaagttgt aaaatcagca ttttgagcta atactgaggg tcatctgatt
     6301 ggacactgtt tattcggaaa gagggacttt gacacgactt tggtcacagt cccttttttt
     6361 atttatgata gacggaaagc caatcatttt attattcatc aaaagagata gaatagataa
     6421 aagaggagaa tgatttattc cgaaaagtga aaacatataa caaaaaatta gaggaaatca
     6481 aatgaatgaa aaagaatggg atgaatttgc tgaagaatat tatgaaatcc agcaagaatc
     6541 gcaagtaact attgctgaag atgtaaaaaa ttatctgaaa acggagaaag tcctgcctgc
     6601 tgaaacagca gcagacgttg ctggaggatc tggcagattt ctttccttag caaaagaaat
     6661 taatcgctat gatttgatcg atttttcttc aggaatgcta gaaaatgcaa aaaaagaagc
     6721 agaaaaaaat gagttgccaa atgtttcctt tatcaaacag tcgttagaag aatttatcca
     6781 atcaaatgag acatatgaaa tggtttttac agcagcaaat ccagcattgg tacatcttat
     6841 tcaattagaa aaattgatga aaaagtcaag caaatggtgc gtgataatca gagtagtgga
     6901 atcaatcgat gatgtttttt atcctatcga aaagcaacta ggaatgatag aagaagatcc
     6961 taatacatcg ccagttgtaa tggatcaatt tgaaacatac ttaattgatg aaggattcaa
     7021 agtgaagaaa aaagatttta cttattttac acaggaatca attactgaag aattgatgaa
     7081 gctatactat gacgcgtacg caaaagatcc tgttgtgacc aggtacattc gcaaactatt
     7141 cagtgaaaaa cgagaaatcc ttagtacgac taagctgacc tatagactgc tcctttggtc
     7201 cgcagataaa aaaagaacct ttcacgactc gtgaagggtt ctttttatga ttttattata
     7261 ttttgtagta acgaatatca ttttcgatct ttgtaatcga aaaaggtaca tctgaagtat
     7321 attctgcaca ttctccgtgt tcaggaagcg tctcactgaa aatcgtttca tattcgtcaa
     7381 cagtgatccg tgttcgagaa tctagcatct cttgatgaga ttgtgcgaag agatattctt
     7441 gatagttttc ttccagataa cctgtaaaaa attcacttac tgcaccagaa ccgtagctga
     7501 atagaccgat gcgatctcct ggctgtagtg atttcgaatt ttccagtaga gaagttagcc
     7561 ccaggtataa tgaaccagtg taaagattac cgattcgtcg gctgtaacgg atgctttctt
     7621 catagcgagc cataagacgt tcctgatttt cttcgtctgt ttggtctaat acgctttgca
     7681 atgccttttt tcccatctta gtatacggaa tatggaaagc aatcgcctga taatcttcga
     7741 gtcctcgacc cgacaattct ttatgtcgat tccaaacttt ttggaatgat tcgatatacg
     7801 tagaattaga taaaggacca tcaacaacag gaaattcgct ataatctgga cgccagaaat
     7861 catagatatc ttctgtcaga aatacgctgt cgtcttcaat cgataaaata cgcgggtttt
     7921 gagtgatcat catcgcaaca gcaccgacac cttgcgtcac ttcaccaccg cttgccaagc
     7981 tgtaacgagc aatatcactt gctatgacta gtacttttcg ttctggatga tttttgacat
     8041 attctttcgc catgtgcaaa gctgcggtgc caccgtagca agcctctttt acttcaaaag
     8101 aacgagcaaa agattggatt ttcagtaaat ggtggataat taccgcactc gcttttgaat
     8161 gatcaatccc ggattctgtt ccgacgatga ccatgtcgat tagctcacgg tctttttctg
     8221 ttacgatttt gctggcagca tttgctccta gtgtaatgat gtcttcattt gcacgattga
     8281 ctgccatttg gtcttgacca atccctatat ggtattttgc aggatcatcc ccacggcttt
     8341 ctgccaactc tgtcatatct aaatataaat taggaataaa aaaggaaaga cgatcaatcc
     8401 ctattttcat ttcaacacct ctttacttat gataaaaaac ttactttact aaggtatcat
     8461 aaaaagatta aaagaaatat aaaaaagaga atatttaagg attgttaaaa tttaatctta
     8521 gaaaaaaata actggaacaa gagctatttg tttttacagc aaagaatggt atatttttgt
     8581 aggaggtggc ttacttgaaa gaagtcgtta tgatagatgc tgcaagaacg ccgataggaa
     8641 agtatcgcgg aagtttaagt ccatttactg cagttgaatt aggcacactt gtgactaaag
     8701 gattattaga taaaacaaaa ctgaaaaaag ataaaatcga tcaagtaata tttggaaatg
     8761 tcctgcaagc tggtaatggt caaaatgttg ccagacagat tgctttgaac agcggtctcc
     8821 ctgtagatgt cccagcaatg acgatcaatg aagtttgcgg atctggtatg aaagcagtga
     8881 tcttagcacg ccagctgatc caattaggtg aagcagaact tgtgatagcc ggcggaacag
     8941 agagtatgtc tcaagcacct atgctgaaac agtatcagtc agaaacaaat gaatatggtg
     9001 aaccaatttc cagtatggtc aacgacggat tgactgacgc attttcaaat gcacatatgg
     9061 gattaaccgc agagaatgtt gcaacacaat tttctgtgag cagagaagag caggatcgct
     9121 atgccttgtc gtcccagttg aaagcagcac atgctgtcga agccggtgta ttttctgagg
     9181 agatcatccc agtcaagatt tctgatgaag acgtgttatc tgaggatgaa gcagttcgtg
     9241 gaaatagtac attggaaaaa ctgggcacgt tacgtacagt attctcagaa gaaggaactg
     9301 taacagcagg aaatgcttcc ccgttgaatg acggtgcctc tgtggtgatc cttgcatcca
     9361 aagaatacgc agaaaataat aatctgcctt atttagcaac catcaaagaa gtagcggagg
     9421 tcggtattga cccaagtatc atgggaatcg ctccaatcaa agccattcaa aaattgacag
     9481 atagatcagg aatgaattta tcaacaatcg atctttttga gatcaatgaa gcatttgcag
     9541 cttcttctat cgtagttagc caagaactgc agttagatga agaaaaggtc aatatatatg
     9601 gaggagcaat cgcattaggc catccaattg gtgcaagcgg tgcacgtatc ttgactacat
     9661 tagcttacgg attgcttcgt gaacagaaga gatacggtat tgcttcatta tgtattggtg
     9721 gaggtttagg cttggcagtc ttgttagaag cgaatatgga gcaaacacat aaggatgtgc
     9781 aaaaaaaaaa gttttatcag cttacgccat ctgaacggcg cagtcaatta atagaaaaaa
     9841 atgtattgac acaagaaact gcgttgattt ttcaggaaca aacactttct gaagagctct
     9901 ccgatcacat gatcgaaaac caagtgagtg aagtggaaat cccaatgggg atcgcgcaga
     9961 attttcaaat caatggcaag aaaaaatgga ttccgatggc aacagaggaa ccatctgtca
    10021 ttgcagctgc aagtaatggt gcaaaaatct gtggaaatat ctgcgcagaa acacctcagc
    10081 ggctgatgcg agggcaaatc gttctatcag gaaaatcgga gtatcaagca gtgatcaatg
    10141 cagttaatca tcgaaaagaa gagctgattc tttgtgcaaa tgaaagttat ccttcaatcg
    10201 tgaaacgcgg gggcggtgtt caagatatct ctactcggga attcatgggg agtttccatg
    10261 catacttatc tattgatttt ttagtggatg taaaagatgc aatgggcgct aacatgatca
    10321 actcgattct tgagagtgtg gcaaacaagt tacgggagtg gttccctgaa gaagagattc
    10381 tattcagtat tttaagtaat tttgctacag aatcattggc ttctgcctgt tgtgaaatcc
    10441 cattcgaacg cttagggaga aacaaagaaa tcggtgaaca aattgccaaa aaaatccaac
    10501 aggcagggga atatgcgaag cttgaccctt accgtgcagc aacgcacaac aaagggatca
    10561 tgaatggtat agaagctgta gtggcagcta caggaaatga tacacgtgcg gttagcgctt
    10621 cgatccacgc ctacgcggca agaaatggat tataccaagg attaacagac tggcagatca
    10681 aaggggataa actagttgga aaactaacgg tgcctttggc tgttgccaca gtaggcggag
    10741 cttccaatat cctgccaaaa gcaaaagcat ctttagctat gttagatatt gattcagcca
    10801 aggaactagc acaagtaatt gctgcagtag ggttagctca aaacctggct gctttgcgtg
    10861 cattagttac agaaggaatc caaaaaggcc acatgggact tcaagctcgt tcattagcga
    10921 tctcaattgg ggctattggt gaggaaatcg agcaagttgc gaaaaaatta cgtgaagcag
    10981 aaaagatgaa ccagcagaca gctatacaaa tattggaaaa aatccgggaa aaataaaaaa
    11041 gcaatatctt tagaagaata aagcaagatt tacagttatt ttatttactg cagatcttgc
    11101 ttttttggct cttcgtcaaa ttgtgttggc gaagacaaat ttgaataaaa cttagtccga
    11161 tatgcggcgc gttctgtgcg ccgcatattt ttttagtttt caaagatcag accttgttgt
    11221 aaatagatcc gtgcccgaaa gttataaaag ttgcgataac caaacgcaat tcgtttaatc
    11281 agcttgatct tgttattcag cccctcagtg acgccgtttg agtggggcac cttaaaggca
    11341 tttgaaatac ccgattggta gcgatggaag atcgtgaatt tctttttaaa cgactgaggt
    11401 aacgtagatg aaattgtttt aagggtttct tgaaagcctt ccgta
//
LOCUS       DADVXK010000090        11357 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.091, whole genome shotgun sequence.
ACCESSION   DADVXK010000090 DADVXK010000000
VERSION     DADVXK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.091"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            99..1055
                     /locus_tag="KB909_002216"
     CDS             99..1055
                     /locus_tag="KB909_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBB6838217.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            1145..2248
                     /locus_tag="KB909_002217"
     CDS             1145..2248
                     /locus_tag="KB909_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBB6838218.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            2261..3214
                     /gene="menA"
                     /locus_tag="KB909_002218"
     CDS             2261..3214
                     /gene="menA"
                     /locus_tag="KB909_002218"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBB6838219.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(4149..5495)
                     /gene="gor"
                     /locus_tag="KB909_002219"
     CDS             complement(4149..5495)
                     /gene="gor"
                     /locus_tag="KB909_002219"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBB6838220.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGIGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(5629..6882)
                     /locus_tag="KB909_002220"
     CDS             complement(5629..6882)
                     /locus_tag="KB909_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6838221.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(6888..7811)
                     /locus_tag="KB909_002221"
     CDS             complement(6888..7811)
                     /locus_tag="KB909_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6838222.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(8032..10524)
                     /locus_tag="KB909_002222"
     CDS             complement(8032..10524)
                     /locus_tag="KB909_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBB6838223.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(10531..10998)
                     /locus_tag="KB909_002223"
     CDS             complement(10531..10998)
                     /locus_tag="KB909_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBB6838224.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(11134..11207)
                     /locus_tag="KB909_002224"
     tRNA            complement(11134..11207)
                     /locus_tag="KB909_002224"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11171..11173),aa:Arg,seq:acg)
     gene            complement(11265..11338)
                     /locus_tag="KB909_002225"
     tRNA            complement(11265..11338)
                     /locus_tag="KB909_002225"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11302..11304),aa:Pro,seq:tgg)
BASE COUNT         3366 a         2323 c         1995 g         3673 t
ORIGIN      
        1 ttgaaatatt acatgggtta tttatcaaaa atagttgact tataggctaa aaagattaga
       61 atgtataatg aatcacaaag aaaaattgtg gactagaaat ggaatggtgg ggtattaaaa
      121 tgaagaaaaa acgttttgta actggatttg ccgtattagc attttcagct ctagtgttag
      181 gcgcttgcgg cgcagatgac aacggaagct caaactcttc ttctgaatca tctacagcac
      241 aatcttcgac tgcaaaaagc acaacagaat catctgcaaa agttgtagct ggcggagatt
      301 tgcaagacgg cacatataaa ttagaagaaa aaaattattc aaatggttac cgtgcagtct
      361 ttgaaatggt tgtaaaagac ggcaaaatca ctgaatcaaa atatgataac gtcaatgaaa
      421 acggcgaatc aaaaacaaaa gatgcagaat acaacaaaaa catggaagca aaatctggca
      481 caaacccaga aaaatacatt cctgagttga atgaccaatt cttaaaagca caaagcgcaa
      541 gcggtgtgga agtcgtaact ggagctactc actcatctga aagcttccaa aactacgcac
      601 aacaattgat ccaagctgct caagctggta acacagatac aatcgaaatc gacaatggtg
      661 ctgatttgaa agacggcact tacaagcttg aagaaaagaa ctactctaac ggctaccgtg
      721 tgcaattcga aatgacagtt gctggcggca aagtaactga atcaaacttt gattatatcg
      781 acaaagacgg taaatcaaaa caagatgata cagaatataa tgaaaatatg aaagcaaaaa
      841 gcggtacaga accaaaaact tacatcccta ctctgaacga cgaattcgtc aaagcaatgg
      901 gcgaagaaga tggctcacct gctaatgtag aagttgttac aggtgctaca cacagctcac
      961 attcattcat catgtacgca caacaattag tgaatgcagc tgaaaaaggc gacactcaaa
     1021 caatcgaagt agataatatc gtaacagaaa aataatcaca taatcatact aataaaagtt
     1081 ggagggtggg acgatagcca gattaggcag tcgtctcacc tttcaaaatg aagagaggaa
     1141 aaagatgcgg aaaaaactac tattttcctt aatcacactg ggcatctctt ttatggtgct
     1201 aactggctgc agcaactcag caaataaaac aaccactgaa agttcagcag ctaccaagat
     1261 attgaaagat ccatattctg atgaacagtt cttgttaggg acttacgttc gtatccgtgt
     1321 gtatgatgaa ggcaaagaat cagcattgaa acctgccttc gatcgagtaa aagaacttgg
     1381 tgataaaatc acgatcaatc aaaaaggttc tgagatcgat gaagtgaatg agcaagctgg
     1441 gatcaaacca gtaaaagttt ctgatgacgt ctacacgtta gtcaagcggg cctacgaata
     1501 tagccaagat tctcaaggcg gattcgatat ggcgattggt gcaatcacac aattatggcg
     1561 aatcggtttt gatgacgcca gaaaaccttc ccaagaagaa atcgatcagg cattgaaatt
     1621 agtggattat cataagatcg aactaaatga caaagaaaaa actgtttatc taaaagaaaa
     1681 aggaatgatc atcgatttag gtgcaatcgc caaaggttac attacggacg aagtagtgaa
     1741 agtcttgaaa aaacaaggag tgaccactgc catcgttgac ttgggcggta atgtctatgt
     1801 cttaggccac agcccaagag gcgaaaacca agactggaca gtcggcatcc aagatccgaa
     1861 catggctcgc ggatctgttt taggttctat taaagaacgg aacaaaacat tagttacctc
     1921 tggaatttac gagcgttatt tagaagtaga tggcaaaaaa taccatcatt tgtttgatcc
     1981 aaaaacgggt tatccgttcg acaatgatat cgcaagtgtc acgatcataa cagataaatc
     2041 aattgatggt gacgggttgt ctacagcagt cttttcaatg ggtgtgaaaa aaggactgga
     2101 atacgtcgaa agcgaattga ataacgggac ggaagcgatc ttcgtgacaa aagacgataa
     2161 agtatatgtg accgatccaa tcaaagacac cttcaaatta tcggaggact cccattacac
     2221 gatgggtgac cgttctgaac taaaataagg agtacgaacc atgacactaa aaatcttttt
     2281 agaagtagtt gaaatacgaa caaaggtggc tagtgtattt ccttttgcgg taggggtatt
     2341 attctctatc gctttttttc atgagataca ttggctaaac acttttttat tttttattgg
     2401 aatgctagtt tttgatttag cgactaccgc tatcaataat tacatggatt atgaaaaggc
     2461 tcattctgaa gtatataagt atgaagaaaa tgtcattggc cgcagaaatc tatctcctgt
     2521 attgattcga aacatgattt tagctatgat tgcatttgtt tttgttatcg gcgttattct
     2581 aacgatcaat acgggttggc ttttactttt gatgggattt atctgttgtt ttattggagt
     2641 attctataca ttcggaccga ttcctttatc tcgaatgcct ttaggggaaa ttttcagtgg
     2701 ggtgactatg ggccttggaa tttttgccat ggtcgtttat gtcaatacat tcggttcaga
     2761 tgtctatgat ctgacagtca acttttcatc tggacaattt gctttggtag gaaatctttg
     2821 ggctatagca gcaatcgtat tagcttcctt acccttggtg tttacgattg ccaatatcat
     2881 gttggctaat aatttgcggg atcttgaccg tgatattgaa aatcatcgct atacactagt
     2941 tttttatatc ggacgtcctg cgggaacagt cttattccag ctattgatgt atgcttgcta
     3001 tttcgtgatt ttaatggggt tgttgagcgg tatctatgaa tggccgatct tggtcacctt
     3061 cttgaccttg ccaattgtga agaagcattt ggatcaattc aagcaaacgt taccccagcc
     3121 tatcagtttc agctattcca tcaaaaatat ggtcttattc aatgccagtt atgtattggg
     3181 gctattacta acaatcatta tgcaagccat ttaacagcat gaagaggttg tgaaaaaact
     3241 gccctgcatc aagtaataag aacagccaaa taaaaatagc tccttatatt tttcgtttgg
     3301 ttgggcttat taccgcagat gcaagctttt gaacaccgtt tatcaggagg ttgtgaaaaa
     3361 gtcgcttagt ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat
     3421 aaatttggct taataccgag aaactggctt ttgaacaccg tttatcagag gttgtgaaaa
     3481 agtcgcttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca catttttgca
     3541 taaatttggc ttaataccga gaaactggct tttgaacacc gtttatcaga ggttgtaaaa
     3601 tcagtgtttt gtcctgagta ttagagaaac aaatggaaaa atagttcctc atattttgcc
     3661 gttttttgag ctaataccga aggacagctg attgaacact atttgttcgg aaaaagtgac
     3721 taactatgac acaatttttt tcacagtccc ttttttcact tgatttgatt cgtaccagcg
     3781 aacttgacga gaactttctt ggtttggtaa ctatatggta ttcttttaac atcctcgttt
     3841 gcttcttcta atttatttat acaaagtcac acttttttaa acatctgttc ttcgatacat
     3901 ttctatttct tttaaacatc gataccaata ttttgaactt aagagtgcat accaaatgga
     3961 ttcatttact cttcgtcagt tacgaagata atcaaaatct ccaacttccc tacttatttc
     4021 gttttgagaa ttatcgaagc aatcttacat aaataactaa aaaacaaaaa accagaaaat
     4081 cagtatactg attttctggt tttacatggt ttgttcaata aaaagctgtt ggaactgtta
     4141 atattaaatt atcgcatcgt tacgaattct tccgctcctg ttggatggat ggctactgta
     4201 ttgtcaaagt cttctttagt tgcacccatc ttgatagcca cggcaaaacc ttgcagcatc
     4261 tcatcgacac caataccaat agcatgtaag ccgacgattc tttcttcttt tccgacacag
     4321 atcaatttca tttcgcattt ttggcgataa tcatttaatg caaagtacat tggggtaaag
     4381 cgtgaacgat aaactttcaa ttcattttcg ccatattttt ccaatgcttc ttcttctgtc
     4441 aaaccaattg ttgcaattgg tggatgcgta aagacgactg tcggaacaag tttatagtca
     4501 agataagaat ctttctttcc attaaataaa cgttctgata aacgtctacc agctgcgatt
     4561 gcaacaggag tcagatctaa tttaccgatc acatcaccaa cagcaaaaat atgttcatcc
     4621 gttgtatttt ggtatttatc tactttgata aacccttttt tgtccaattc cacatttgta
     4681 ttttccagac ctaatttttc ggtattcggt acacgtccac cggcaaaaag tacacaatca
     4741 ccagttaagg tttcaccatt ttcaaatagc accgtatatt cgtcattgtt tttagtaatt
     4801 tctttagcaa tatgatgtgc gtaagttttt attccagctt cttggtacat ttggatcaaa
     4861 ttgtccgaaa gcattttatc aaacgttcta agtggtcgtt cttttcgata tgcccacatg
     4921 acttcactac ctaaaccacg aaatacacct gaaagttcag ccgcaatgta tccagcacct
     4981 aaaacgattg ctctcttagg taactctgtt aattcaaaaa atccatttga atcaattgcg
     5041 tattctccac caggaatggt cattttactt gcacggcctc cagtagcgat caagatttta
     5101 ggagcacgat aggtttcacc gtttacttcg atcgtttgac tatcgataaa agtagcgtaa
     5161 ccttttatag cctcgacatg attgctatct aatcctcttt gataagcacc gtgtagaaaa
     5221 tcaatatatt tttctcgtct ttctactaga ccggcgaaat caacattttt taaatctgct
     5281 tggataccgt aacttgaggc atctcgttca attgtttcca aaatcgtact tgcttgccac
     5341 ataacttttt taggtacaca accgacgttg acacatgttc cgcccaattc attcgcttca
     5401 atcagcaaaa cttttgcgcc atgcatccct gctctgtttg ctgaagcaat accgccagag
     5461 ccgccaccaa ttacgatgta atcatatatt tgcattttgt tcctccttat tgaagagatc
     5521 aatcaaaacc tttatttaac gatccttttt ctacagaaaa caagtgtaac acttttcttg
     5581 aattttgtat gcgaagatgc ttaaaacagg gatatatcag ctttttcctt atttacgttt
     5641 tcggatcata tctccaggtt tcaccggctg tgcgactggc atagttaaaa tcatcattgg
     5701 atttggtgct cggtcaatgg attcgccttc ttcattatgc ataacttcaa cggtttgact
     5761 gaaatgactg aatcctggac cataaaattc gatttcatct cctacagaaa acaagtttct
     5821 ctgacgtatc gtagcaatct gtgttgcctc atcataagat aatacttcac cgacaaattt
     5881 atatactggg attttacgac gttcaccgaa taattgttcg ttttcagttg gtgtattgta
     5941 gtaaaaacct gtagctaatt ctcgttgtgc tactttccat aactcgtcga tccattcttg
     6001 cttgcagaca tagttttcag gatcttccat ataactgtct acagccgctt tatagacatt
     6061 tgacaccgta gatacataat ggatcgattt cattcttcct tcgatcttga agctgtctac
     6121 gccgttttca atcaattctg gaatatgttc gatcattgac atatccactg cactcatcga
     6181 gaattcttct tccacttcgc ctgtatcagt taaactgttt cgttcttgac caaaaggcat
     6241 atcgaacaat ccatacttcc agcgacaaga ttgagaacat ccgccacggt ttgcatcccg
     6301 catcgacata tggttggaca atgtgcatcg accagaataa gagatacaca tggcaccatg
     6361 gataaatgct tcgatttcgg tatccgtatt tttacgaatc tctgccactt cctccattga
     6421 aacttcacga gctaaaacga cacgttccaa cccttcttct ttccagaatt ccaatgtctc
     6481 aaaattagtt gctgaagctt gagtggataa atggatcggc agacctgggg cttctgtcgc
     6541 acaaatttcg atcaaagctg gatcagaaac aatcactgca gaaataccga catcacgcaa
     6601 actgcggaaa aattcccctg ctccatcttc atttccttca tgggtgacca tattagcagc
     6661 aacgtatacc ttcgcatcat gttcttttgc aaaagcaact ccttcagcca tttcttcata
     6721 agtaaaatta cctgcacggc ttcttaaacc atatgcattc ccgccaatat atactgcatc
     6781 tgctccataa tggatcgcgg tttttaactt ttccagtgtt cctgctggcg ctaggatttc
     6841 tggtcgtttc aattttcttt ttactgtcat ttctttcatc atactcctta tttgatagca
     6901 gaaggatcaa tataaaagaa tcctgtatct aattcacggt tttcaggatg caatttactg
     6961 atttcgctag tcattttttc cgctttttct tgatcccagc taccttctaa aatttgtttt
     7021 tttgcttcgg cgaatagtcg agtgatgttt acgaattttt cgcctggagt aaataatccg
     7081 tccaatttcc atgtacagta atgatgctga taaagttcat tcaattcatt cgagagattc
     7141 agatcattgc tggcaaaaat atgtgtgcca tgactatctt cataaataga ataatgtgtc
     7201 tcttcttttt taggttccga gataaaaaga cctctttcac gatctttttg ttcgtcttgt
     7261 ttcgtatagt tatagtaatt ctgtagcagt ggacgtttgg attgatggat gcatgtagca
     7321 ccatacacaa gggtttctac aggaatatcg agtttttctt ccatcgcctt catctcttca
     7381 aaaggaactt cacgagcaag tactgctcca actgcgcctt ttttcgccca gaaattgatt
     7441 tgacgtgcgc tcgttactaa tgtttcagca tcataaatat acggtatacg caattcagga
     7501 ttttttttca tcgtataaat aatacctgta tcaccaactg tgatcacatc tacgtttatt
     7561 tcttttaaaa aagccaaata ttcaggtaca tttttcattt tttcaggatg aatgatccca
     7621 tttacagcaa tattcgcttt tttaccatac ttgtgtgcta attctaccaa ttgtcgctgt
     7681 tcttctcgtg taaatgaagc aggcagacgc aatccaaatt gctcttcacc gaaatatagt
     7741 gtatctgcac ctgcagcaag caactgttct gcttgttcaa tagtttctac tgtggttatg
     7801 agttcgatca taattttctc ctcctacaac ttcataatag tagcatagct ctaaaaactt
     7861 tccaatactt cttctattta aagtcggatt tttgaaaatt atttcacaaa aaatcaaaat
     7921 aaagttcgat atattctgtc caaatataaa aagagattgt gacaaaaatc ttgtcacaac
     7981 ctcttaatca agtcttacta ttataaaaat tcagctacac aggccaagta actataggga
     8041 acctactgtt tcctttttag gtccgcgaac attcaatgtg atcttacctt ttgaagcacc
     8101 tactgttacg tggtcaccta aacgaatttc tccgccaagc aaagcctcgc tcaatcgatc
     8161 ttcaatttct ttttgaagtg cgcgacggat tggacgtgca ccatattcag gatcaaatcc
     8221 agctttcccg atcacatcga ttgcagatgg tgtgattttc acttgaatat cttgttcttt
     8281 caatcgtttg ataatcgctt tgctcatgat ttggacgatt gtatggattt catctttact
     8341 caatgaatgg aagacgacag tctcatcgat tcgattcaag aattcaggtc ggaaagcttt
     8401 ctttaactct tctaagatac gtttttgcat ggctttgtga tctttagtaa catcttggac
     8461 attgaatccg acattttttt cttctcgaat ttgtgtcgct ccgatatttg aagtcataat
     8521 catgattgta tttctaaagt ccacttttct acctttagaa tctgttaaat gaccatcatc
     8581 caatacttgc agaagtaaat tgaaaacgtc tggatgtgct ttctccactt catctaagag
     8641 aatcactgaa tatggttttt gacgaatttt ttctgtcaac tgtccacctt catcataccc
     8701 tacgtatcct ggaggagacc cgattaatcg gcttgtactg tatttttcca taaattctga
     8761 catatcaaca cggatcaggg catcttcact tccaaacatg acttctgaaa gtgctttggc
     8821 caattctgtt tttccgacac cagttggtcc aaggaacatg aatgaaccaa ttggacgatc
     8881 aggatctttc aatccgcttc gtgcacggcg gatcgcacgt gaaactgctt tgacagcctc
     8941 atcttgacca acgacacgtt catgcagaag tccttccagt tctaacaagc gttcgctttc
     9001 ttttttctcc aactgctgta gagggacacc agtccactcc gatacaactg tagcaacatc
     9061 ttcttctgtt acacgatcag aataaccttg ctcctgtttt gcttcaattg cagaaacttt
     9121 ttgcagcttt ttacgtagtg ctttttcttg tctgcgtaat tgagcagcat tttcaaagtc
     9181 ttgtttttgg atcgctgctt ccttttcttg tactagttca tcgatttcta gtttgatcac
     9241 agttgatttt gttaagtgat cggtttgatc caaacggact ttcgctgctg attcatcgat
     9301 caaatcaatt gctttatcgg gtagttgacg agaagtgata taacgaacag aaagattgac
     9361 tgctgctcgt acagcttcat ctgtgatctc cactccatgg tgctcttcat atcttgtacg
     9421 taatccttga agaatcactt ctgcttcttc aggagttggc tcatctactt gaatgcgagc
     9481 aaaacgtcgc tctaatgcag aatctttttc gatatatttt tgatattcat ctagggtcgt
     9541 tgctccgatc gtttgtaatt ctcctcgagc taacgccggt ttcaagatat tcgaagcatc
     9601 aattgctcct tctgctccac ctgcaccaat taaggtatgc aattcatcaa tgaataagat
     9661 tacttgacca tcattataga tttcgtcgat gacctttttc attcgatctt caaattcacc
     9721 gcgatatttc gtaccagcaa ccaaagatcc catatcaagc atcatcaggc gcttttcttg
     9781 catgtcttct ggcacttcac ctaaaatgat tttttgagct aacccttcag caatggctgt
     9841 tttgcctaca ccaggttcac ccaccagtac agggttattc tttgtccgtc ggctaagaat
     9901 ctggataagc cgtttcactt ctctcgaacg accaacaact gggtccagct tgttttcttt
     9961 tgctaatttc gtcaaatcac gtgctaatga atctagcgta ggtgttcctt gcggtgtttg
    10021 ccgtttatct tgtacattta catttctacg acgattcatt ccttttccag cagaatcacc
    10081 agctagcccc attttttgtt tcagaacttg acgggctttt gaaaggctga tacctaagtt
    10141 gatcatgatt cgagtagcca tgatactttc atcttttaat aagctcatca aaatatgttc
    10201 tgttccaact ttttgagaac cagttttctt cacttcgctg ctagctaaag caaaaacttg
    10261 tttcattctt ggtgaatatg gaagaaagac tcctttaggg taagaacgga taccaccata
    10321 accaatcaga tgttcaattt cttcataaat ttccgtttca ttcaaatcca tttcacgtaa
    10381 tacttttcca gcaattccat tttgctcgac cactaaggct agtaaaacat gttctgaact
    10441 aactgattga tgtttcaacc gttttgcttc ttcttgtgca atttctaata ctgcttgggc
    10501 tctttcagta aaaagttctt ccatctaatc tcacttccca tcttcataac ttaaacgttc
    10561 cagaaatgct cggagaatcc gagcacgtgt atgatcttca tattcattga aattcaatgt
    10621 gttttttgca attgcactca acatcaagtt tccttctttt tttgtaatta tttggtcttc
    10681 ataaagtttt tgaataatag caaaagcatt tttctcactg attgtatcat caaataactg
    10741 atttatctgc tcaagtaatt gttttttatc tgaaatcctt acttttgcaa ttcgtatata
    10801 accaccacca ccacgtttgc tttctactag ataaccacgt tggatggtaa aacgggtatt
    10861 aatcacatag ttgatttgtg aaggaacaca gttaaagagg tctgccattt caatccttcg
    10921 aatctcgatc atttcactat tttccagaat tttctttata tatgattcaa ttaaatccga
    10981 ggtattctga tgtgccatct tattcattcc ctttgactaa tattgacctt aattataacg
    11041 aatttgataa tagaaagaaa gaagaacgct ttttgttaaa taaatccttt agaatcaaca
    11101 aaaaaaaata cggaatatac tattccgtat cgacgcgccc aagaggagtc gaacccctaa
    11161 ccttttgatc cgtagtcaaa cactctatcc agttgagcta tgggcgcata ttcaatttaa
    11221 aaaaattata aatcatttga aaacaaaaag caagataaaa aaaatcggga agacaggatt
    11281 cgaacctgcg accccttggt cccaaaccaa gtgctctacc aagctgagct acttcccgtt
    11341 taaaaaataa aaaagac
//
LOCUS       DADVXK010000091        11262 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.092, whole genome shotgun sequence.
ACCESSION   DADVXK010000091 DADVXK010000000
VERSION     DADVXK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.092"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            345..614
                     /gene="rpsN"
                     /locus_tag="KB909_002226"
     CDS             345..614
                     /gene="rpsN"
                     /locus_tag="KB909_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6838225.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            629..808
                     /gene="rpmF"
                     /locus_tag="KB909_002227"
     CDS             629..808
                     /gene="rpmF"
                     /locus_tag="KB909_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6838226.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            840..1217
                     /locus_tag="KB909_002228"
     CDS             840..1217
                     /locus_tag="KB909_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838227.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1238..1387
                     /gene="rpmG"
                     /locus_tag="KB909_002229"
     CDS             1238..1387
                     /gene="rpmG"
                     /locus_tag="KB909_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6838228.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1411..2394
                     /locus_tag="KB909_002230"
     CDS             1411..2394
                     /locus_tag="KB909_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6838229.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2424..2546
                     /locus_tag="KB909_002231"
     CDS             2424..2546
                     /locus_tag="KB909_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6838230.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2564..4087
                     /locus_tag="KB909_002232"
     CDS             2564..4087
                     /locus_tag="KB909_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBB6838231.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            4111..4350
                     /locus_tag="KB909_002233"
     CDS             4111..4350
                     /locus_tag="KB909_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838232.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4543..5004)
                     /locus_tag="KB909_002234"
     CDS             complement(4543..5004)
                     /locus_tag="KB909_002234"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6838233.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5199..5417)
                     /locus_tag="KB909_002235"
     CDS             complement(5199..5417)
                     /locus_tag="KB909_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838234.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5535..7151
                     /locus_tag="KB909_002236"
     CDS             5535..7151
                     /locus_tag="KB909_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6838235.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7392..8732)
                     /locus_tag="KB909_002237"
                     /pseudo
     CDS             complement(7392..8732)
                     /locus_tag="KB909_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9008..9163)
                     /locus_tag="KB909_002238"
     CDS             complement(9008..9163)
                     /locus_tag="KB909_002238"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6838236.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9459..9791)
                     /locus_tag="KB909_002239"
     CDS             complement(9459..9791)
                     /locus_tag="KB909_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838237.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10305..10496)
                     /locus_tag="KB909_002240"
     CDS             complement(10305..10496)
                     /locus_tag="KB909_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838238.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(10590..10976)
                     /locus_tag="KB909_002241"
     CDS             complement(10590..10976)
                     /locus_tag="KB909_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6838239.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
BASE COUNT         3741 a         1779 c         2170 g         3572 t
ORIGIN      
        1 ggcgataaac cagttaaaca taaaagattg aataaaaagt tatagtttct ttcatattgc
       61 cgttttaagt agaggaaaag ctacttaaaa cggtatttgt gtttgattgg actaataaaa
      121 gtgaattctt atttttcaga gcctaaactg catattcttt taaatgattt gattatctct
      181 atgtaccgat aaattcgttt tcaaatagtt atctattcat atgagtttta tttcatgtta
      241 tttattgttg acaagagcaa ctcttgttgg taaagtatca gtgtcaaaac gtaacgatta
      301 cgatttgagg tgtctaaatc aaaataaaag gagtataaag gtatatggca aaaaagtcga
      361 aaattgctaa agcaaagaaa caaatggcga tgattgaaaa gtatgcagat aaacgtcagg
      421 aattaaaagc cgcaggagat cgcaccgctc tcgctaaatt gccaagagat tcaaatccga
      481 atcgtctgag gcttcgtgat cagacggatg gtcgtccaag agggtatatg cgaaagttcg
      541 gtatgtcccg tattaagttt agagaacttg cccatcaagg gttgattcct ggagtaaaaa
      601 aagcaagttg gtaaaaggag gaaatatcat ggcagtacca gcaagaaaaa catctaaggc
      661 gaagaaacgg ttaagaagaa ctcatcaaac tgtagtaaaa ccagaaattt catttgacga
      721 agcgaatggt gattatagac gtagccatca tgtatcttta aaagggtact ataatggaaa
      781 gaaagtaatt aaaggagctt caaaatagtt taatatataa cttttaggag ggaatcaaaa
      841 tggaaattat ttacccacct ttagttgaag aaggattaaa gtattatctt gaaacgaccc
      901 agcaatcgct agataaatgc actttttatc gttcgatggt agagagagga attattactg
      961 aaacgggttt accgacccaa caggcaattg aaaatggatt agtcaaagat tactatgagg
     1021 accaaggctt atcatttgat gattttttaa gaatctatcc aatttttgaa gagtatgacg
     1081 aggagttatt tcaatgtatc gatggttatt gggagatacc tgttgatatg aaagaaaatt
     1141 tagtttcaca attggaatct ggcgagttaa cttttgaaga tgcacaacaa attcaagcat
     1201 atcttgaaga tcgataagta ttgaaggagg aagatttatg cgtcaaaata ttattttgga
     1261 atgtgtcgaa actggagaac gtctgtatct caccagcaaa aataaacgga ataaccctga
     1321 acggttagaa ttaaaaaagt attcgccaaa attgcgcaga cgggcaattt ttaaagaagt
     1381 gaaatagcta agtggtaaaa aggtgacaaa atgggcatac cagttacaat cgtttctggg
     1441 tttttagggg ctggaaaaac aacgctaatc aatcaagcct tgcaagtctc accctacccc
     1501 agggaagaaa ttattataat tgaaaatgag tttggtgaag ttgggattga tcacaaatta
     1561 ttagttcata gcgaggaacg ggtgttacaa ctaaataatg gatgtatgtg ttgcagtctt
     1621 cgcagtgatt tattagcaat attgatttct ttactggaaa caatagaaga acatcaacaa
     1681 ccaatttcac aaatcatcat tgaaactaca ggtatagcag atccccaacc aatcattcaa
     1741 acacttttaa cagcgcctca actaagagga agagtatata tcgatagttt attgactgtt
     1801 attgatagtg acagttttga acttattgaa agagaaccac aagcccttaa gcaacttgtc
     1861 atggcagatc gcatttttgt gtctagaaaa caaaacttga atttatctgc actaaaaaaa
     1921 ttacagagag aaatcaaaag tattaaccct ttatccgata ttcgaatgtt cacacatagt
     1981 gaaacgattc aaaaaaagga tttttataat ttgaaaaaat ttaatcatcc cttagttttt
     2041 gaaagtgatt catcagaaaa tcactataat ggcaaatact atcatcaaca ccatcaagta
     2101 catgagttta aatcaattct cttaacttca gatcaagaca taaaaaaaga ttttttactc
     2161 caatggattg actggctgat tttaaccaac caagggagcc tgtatcgttt taaaggattg
     2221 attgctttac aagagcagga ttttatagtt gccatgcaag aggtaaacga acaggttaat
     2281 tttcaataca ccactcgaca aaaagaccaa accactatta ttctaatcgg aaaaatgttg
     2341 gatgaagaaa ggatcaaaca gagttttgat aaattactgg cggaaagcaa ataatgataa
     2401 gtagtgattg ggggtaattt ctaatggaga aaacggatat atctagtgca tatcgacgac
     2461 ttaaaagccc gaatattaaa actagaaaaa gggcattaaa aattatcaaa gaacataaac
     2521 gaaataaaat gaagaaatta gcataattaa ggaaggaaaa agaatgaaga aaatcagtgt
     2581 aggacttatt gggatagcag ctctaggatt attgggagct tgctccagca ctaatgatgc
     2641 aaaagtatcg aatgataaag atggaaaatt agaaattgta acaacattct atccaatgta
     2701 tgatttcacc aaaaacatcg tcggcgatga agcgaacgtg gatttaatgg ttccagcggg
     2761 atcagaacct catgactatg agccctcagc taaggatatg gcaaaagctc atgatgctga
     2821 tgtttttgta tatcataacg aaaacatgga atcatgggta ccaaaagcta aagaaagttg
     2881 gaagaaagct gggcctaatg tagtagaagg aacaaaagac atgattttat tgccaggtag
     2941 tgaagaagaa gatcatgatc acggagaaga agatcaccat catgaactag atcctcatac
     3001 gtgggtttca cccaaaatgg caattaagga agtttcaaat atcaaggatc agttagttaa
     3061 attgtatccg aaaaaagcaa aagtatttga gacaaatgct gaaaagtatt tgactaaact
     3121 gaaacggttg gatgctgact ataccactag tcttaaagaa gcgaaacaaa aaagttttgt
     3181 gacgcaacac gcagcctttg gatatttagc tttggattat ggattgaaac aagttcctat
     3241 tgctggacta agtcctgaag aagagccatc ttctggtcga ttagctgaat taaaagagta
     3301 tgttaaaaaa aataagatca attatattta ctttgaaaag aatgctaatg ataaaattgc
     3361 aaaaactttg gccaacgaag ctgggataaa attggaagta ctgaatcctc ttgaaagtct
     3421 tacaaaagaa caaatggata atggtgaaga ttatgtttca gtaatggaag acaatctaaa
     3481 agcgttagaa aaaacaacta tggttgctgg tgaagaggta gttccagaaa aagaagcgaa
     3541 ggatgaaaag acagttgcta atgggtactt taaagatgcc gatgtgaagg atcgcgaatt
     3601 gagtgattat acaggcgaat ggcaatctgt ttatccgttg ttaaaagatg gaattttgga
     3661 tgaagttttc gattacaaag caaaaatcaa taaagacatg acagctgccg agtacaaaga
     3721 ttattatact actggctata agacagatat tgatactatc aacattaaag acaacaccat
     3781 tgattttgta gtcaacggtg aacatcatca atacacatac aaatatgttg gatacaaaat
     3841 tttgaattat gaaaaaggaa accgtggtgt tcgttttaat tttgaaactg atgatgcagg
     3901 tgctggtcgt tttaaatata ttcaatttag tgatcatgga attgcaccaa gtaaggcaga
     3961 gcatttccat attttctttg gtggagaaag tcaagaaaaa ctctataatg aattgcataa
     4021 ttggcctact ttctatccag cttcattgtc taaacatgaa attgctcaag aaatgatggc
     4081 tcattaaaat tcaatttttg gaggaaatac atggtaagaa aagtattatt gtctatggat
     4141 tccaagaata ttgatgctta tcggcgttat cgatttgcaa agcaaatgag attaaatggg
     4201 agtacattag ctgatattgc tgcaacttta catgttagta ttgacacagt tcatagagta
     4261 ttaaaacggg atcctgattg ttgttttatc aaggtcaata ctggaagaag tagacgttta
     4321 gcaaaacggc ataatagctt ggccaattaa ttgataatac cagagtagat catttttccc
     4381 ttatttggat ttgatctgct ttttattatg tcttgaattg tcaaatcaag cgcaacactt
     4441 tatcaaagaa gacttcataa ggtgttctcc aatctaaaca ctttctaggt ctgttattca
     4501 gtttttcaat catctgattt atcgttgagt tatctaccgt agctatctct ttcgattttg
     4561 gcaagtattc tcgaatgagt ctattcgtat tttaatttgt tcattgttgc caagggcatg
     4621 aggatctgga aaataaaagg gcatattatt caatgcttct gtaactgcga aatgattgga
     4681 gaattctttt cctctatctg gagtgatcgt tttgaccgcc tcatttggaa tactgcttaa
     4741 aagttcaatc attttctcgc tcacataagc ggctttcttt ctggggacct tctttcctgc
     4801 taaaaggaag catgattttc tgtctgtcaa agtcactaaa caagtaccac cagttttgcc
     4861 agctacaata tcggctttcc aatgaccaaa atcacttcta tcatctgcgg attttggacg
     4921 gccatggatc gaatgagtaa ggcaaatctt tccacgagac tcgacatgat tttttgtatg
     4981 tcttgttttt cctcgatggt gcaatgaacg gatcaggcct ttattgccgt gtgagagggg
     5041 ttctgtatcg aaaagatcat tgcaaattgc acgttagatc gtgataaaac taattgaaaa
     5101 gtccatatgt tcatgcttca aacgattcga gatttcctct ggcgaccact gaaaatcgac
     5161 aaataaatga cgaacaattg accaaactca cggatcattt agaatgtgat aacgtccgca
     5221 tttttttctt cgataagcat aatttttttc cgctttggaa ggtgaatagt ttttttcttg
     5281 tttcttctca gttcatgtaa aatagtaaac gggctatgct gaatgtcgtt gccaattata
     5341 ctaatagaaa atccttcttc gtgaagcaga aagattcttt ctcgttcgag tatagtaaga
     5401 tgacgatact ggctcataat tattttcctt ctaggagtgt tctcgacaaa cttatactag
     5461 ttggatatcg attatgactc atttttatgt gttgcactta aagtgtaaat tcaaggtata
     5521 gaaagaggtt ccctatgaaa aaaataccta ttacaatctt aactggctat cttggttcag
     5581 gaaaaacgat acttctaaat catattctgt acggtgatca cggaaagaaa attgctgtca
     5641 ttgtaaatga cataggggaa gtaaatgttg atggggtatt agtcgacaag aaaggtttta
     5701 aaagaactgg agaaaaactt gtttcgatgc cgaatggatg catttgttgt acattacgcg
     5761 aagatttgat tgttgaacta gatcaattag tgcaattttc tgacttgaat caaattgtta
     5821 ttgaagcttc aggaatcagc aaaccaattc caattattca agcaattata ttagctaaaa
     5881 accctttaga cattgatttg acccaacgat tagagattgg tgccattatt atagtagtgg
     5941 atgtaaaacg tttttgggat aatttcgaaa cgggtgaaaa gattcaggaa agaaaagctg
     6001 aaggtaatgt agttgaagaa gaacaggata ttcgtggctt gttaattgat caattcgagt
     6061 gttgtaacat attactttta aataatagtg acttagtgtc aaccaagacg atttacaaaa
     6121 ttaacggtct aattgctaag ttacagtcca atgccaaaat aattaggaca attaaaggtg
     6181 aagtagactt atcgaaaatt ctaaatacaa atctttttaa tatagatgag acttcctatt
     6241 cagtgggctg gttcaaagag ttagagcttg gctatcaaaa tcatattcct gaaacagaag
     6301 aatatggtat ctcaagtttt atctatcgaa atcggttact ccttgacgca caaaaatttg
     6361 cccatcttac ggataaaaat tttcctggca atattacaag agcaaaaggg tttctttggt
     6421 ttgcccaaca tagtgatttt tcgacgatct ttgaaacatc gggtagctat aaaagtattg
     6481 aatcattaaa ttattgggta gctagtttac ctaaaattga gtgtcaaatg attatacaaa
     6541 aaaatcccga attgaaggaa gcctggcatc cgttgtttgg tgaacgcatt aataaactag
     6601 tttttattgg tatgaagatg gatcaacaat gtattaagga acaacttgag ggttgtttaa
     6661 ctgattctct taatgcagat aatttccgaa aaatttcacc atttccatgg aaaaagtcta
     6721 atatgtttag ccagatatcg ttaatgaaat ttttaagaaa agctggtgtc aagataggcg
     6781 atgtcataat tattggcatt ttgattatta cctcttttat tcccttattt gtattctcta
     6841 tagaaaagga gaatgaaaca actgaagatg ctatcaaata tgccatcgtt cgaattgatg
     6901 gcaaggaaat ggatcgcttc gatttggata agatcaatca taaactcgtg aattatcatc
     6961 ctgcgaaggg acaatataat attgttgaga ttaaagatgg aagaattcga gttaaagaag
     7021 ataatagtcc tgatcaaatc gcggttagaa ctggatggat ctcaaaaccc ggtcaaacga
     7081 gtatttgttt accccataag ttagttatta gtattgagaa aaaagaaagc acagattact
     7141 acatttacta atctggaaat agatgaggag gtttttaata agaaaaagat attattatta
     7201 ataatagcag gggctttatt aagtgtgtta agcgcttgtg gacaagaaaa agaagcggtg
     7261 acaacaggca caagtatctt taacgggacc tgcaatggtt tagttaacag tcggttagat
     7321 tacttatttt ggctcttcgt caatgagtgt tggtgaagaa attcaataga ataatcgaga
     7381 tactcacacg gctagacagc tatcttgtct agccgtgttg ttgttctggc tttagtcagt
     7441 tgggtagtat tcttagtttt cttaaaatat tttcctcgat ataaaaagat tcgttctcgg
     7501 tagttttgaa agtttctata gccataggca attcgtttta gtactttgat atggttattc
     7561 aaacattcta tagggccgtt ggaataggga acgcgcaacg ctcgtttgat ttctgtttgg
     7621 tatttcttga aggtcgtgaa cactggttgg tagtgctctg gcaactcctt gtagtcttct
     7681 tttaggagcg cgacgaattc aggaacatct tgtcttctga taacggaaag aaaatcctgg
     7741 tagacttcgt agcctcgctt taaggaatca tcataagata atagccgatc gactatctct
     7801 gcttctgtca gatgatctcg aaatgacgga cgccagtagc gatgctgacc tttcaattcc
     7861 cacgcattct tttgaagtag tttccagtat ttctttaagt gcttcgaccg acgatcccct
     7921 tttttaaagg tcttcattac ttgaattcgg tggttggtaa aagcccgacc aatgtgttgg
     7981 ctaatatgaa agcgatcggc gacgattcgg gcattcggaa aacactcttt caccaatgtg
     8041 cgatagggtg tatagaaatc tgaaaccact agacgcactt gttcacggac ttttataggg
     8101 tagcgcaaga aatagtcgcg taaaggattg agttgccgat tttccacaat atcaatcagt
     8161 tgatgggtct tgccgtccat catgacaaag ctcatggctc ccgagacatt tttcactgat
     8221 ttgaattcat cgaaacacac cacttctggt aacagctggc tcaaagaaat ggttttaggc
     8281 cgaaggctgc gaagtattcg aatgacagtg gtcggagaaa tgtgcttcat acgtgcgatc
     8341 aaagacatag aaagaggttc gcttaatagc tcaagaatgg cttgtttgac tctgcgagca
     8401 atggagcagc gacgatcact aactgaatct tctgctaaaa aagtctttcc acagtgttta
     8461 catttgaagc gctgtttgtt aatccgcaga atggtcttgt agttactgac atcattcaat
     8521 aagatggata cttttttcca gccctattta atgatcgttt gttcattttg atagtggcga
     8581 tgaaagcatt cctccggttg ataggtcaat gtgccatcaa aaacaaaaca tgtttcgtca
     8641 ttgattcgct ctttgcgaaa ggcatcttca tgaaagataa gatttaggtc tagaatatct
     8701 agtaactctt tggtaaactc tgaataggac atcttgaaac actcctttga atggttttcg
     8761 tcgactttat tctaaaggat tttaaggtgt ctgtttgcgt ttattagaaa aaagaaaaag
     8821 tattggcaac agaaggcgtc accaacacta gatattatag atcccttatt ttcttcgctt
     8881 caaattgtca aggagtcatc ataaattttg tatggattct tttgtttggg tagtagtctt
     8941 ctaaataatc ttggattaac accttcatct ctattttact tttatatttg ttggagtcga
     9001 ttaattctca tttgattgat cgatgaaacg cttcaattac tgcattgtca acaggagtcc
     9061 cagtttggct cactgaatgt gtgatgtggt ggtcgttcaa cagctcttga taaataaaag
     9121 accgatgctg gctacctcta tcggaatgaa ttaccgtagg caattctcct taataaattt
     9181 gtaatggacg gacgacaatc tcttttttca tgtgtgaatc taccatatag taacgtagaa
     9241 tacgagttgc taagtcaata taggtggaca aatagaggcg accgtcatta catggaatgt
     9301 aagtaatatc catcacccaa acagcatcaa tttggttctg ttcaaattat cgattcaaca
     9361 tttttttacc atttctttga ttgttttttc tctaccatga gaagatttgc gtcgatgaaa
     9421 tcctcttgtg cataaattca tttcacgcat aagaacagct acaacacgtt tattgatttc
     9481 gattccttca tcgtaaagtt tttgagtgat ccctggagat ccgtatcgat ctttgtgttc
     9541 gtagaacact cgtcttcctc ttttagtcgt ttattttcct gttcaagaat gtagaaatct
     9601 gctttatcag gtaatctttt tccttgtcca gcaaaagcat ttttcccgta tcgacgatat
     9661 tctgaaaccc atcgggaaat tgttggacga gagatattgt attcttcagc aattttcttg
     9721 gtagttactt ttttctcaag gatatcctgt gaaatcttta gtttaaattt acgatcatat
     9781 gtttttctca atagagttca ttccttccgg taacgtaact gatagtcaag aaaagtgtat
     9841 catagcccaa cttagtatca gggtttgtca actaaactgt ggaagttgat agataagagt
     9901 ttttaacaac caaaattctc ttgactattt ttgaaatcag acaaattttg attggacaca
     9961 tagttgaata aatctaccgt cgttacggaa ggtaaatcgc atgcttttca attctagagg
    10021 agaagtcctc gttgaagtac catagcccag ttctggattc gacctcctgc ccacttcata
    10081 cgtaaataaa gtaattttag gagtgagact gtgacaaaag ttatttttaa gctaaaaacg
    10141 aattaaaaaa cgttgataat taaaatcatt cgttttagat tctatgaatc attatagaac
    10201 gctgtaaaat cgatacttta taattataaa gaagatagtt tcaaatttat tgttcgaaat
    10261 ttgaaactat ctttttactt atgtcacaga ctcccttagt tgagttattc tttaatttcg
    10321 aatttcgaga tagctagata tattgcaagc atacattctt gataacaatc ttgatcatat
    10381 tttccagttc tccaggattg cttatgaatc aaagagctaa atcttttgag aattgcctca
    10441 acagcttctt catttccagc ctttgctaaa atgaaatctt cttttaaaga attcataaat
    10501 ctaccttctt cccatggact tataatctat ttctttggga aggaggagaa cgagcaaaga
    10561 agcatacaaa attagttatt atgcagatat taaaccagca ttttttgaat ttttttgtaa
    10621 agtcgatgtt ttaaatttgt cgcaccctgt cttgtaatcc ccagaacctt tccaatttct
    10681 ttatcagttt tatcaaagat aaatttttcg ataagaaaaa tttgttcagg ttctttcaac
    10741 aaaggaagga tttttgctaa ttttatatct tcaacaagga gagtcacatt taaaacatta
    10801 atcggttgtt taaattttat agtatcttta gtaaacaaat atggtgggag ttgatcaagt
    10861 tgttcatgtt tttgaatttc ttcttgtttt ttataataag tattagcggt gttcaaaatg
    10921 accttttcaa agaatcgaat caactgggca tttacgcgtt cgtcgttatc tgacatattg
    10981 cacacctcct ccattaagat ttaaagggaa aagaggcaaa aaacacgaaa agaagctaat
    11041 gcaattatgc tgcgctgcga ataacttcta taagctcaca tgcattgata ggactgctga
    11101 tgtttatttt caaaaatgtt tttttagttg ataatggata gttatcttta tacttagaaa
    11161 agaaaattca tatatcttct taaatatcaa acatgtcctt atggctaaga aaatgtcttg
    11221 agctttttac gtataataaa tcttttctaa aacctccttt tg
//
LOCUS       DADVXK010000092        11200 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.093, whole genome shotgun sequence.
ACCESSION   DADVXK010000092 DADVXK010000000
VERSION     DADVXK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.093"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            162..1421
                     /gene="lysA"
                     /locus_tag="KB909_002242"
     CDS             162..1421
                     /gene="lysA"
                     /locus_tag="KB909_002242"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBB6838240.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1408..2208
                     /gene="dapF"
                     /locus_tag="KB909_002243"
     CDS             1408..2208
                     /gene="dapF"
                     /locus_tag="KB909_002243"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBB6838241.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2211..3092
                     /locus_tag="KB909_002244"
     CDS             2211..3092
                     /locus_tag="KB909_002244"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBB6838242.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3089..3805
                     /locus_tag="KB909_002245"
     CDS             3089..3805
                     /locus_tag="KB909_002245"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBB6838243.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3811..4506
                     /gene="dapD"
                     /locus_tag="KB909_002246"
     CDS             3811..4506
                     /gene="dapD"
                     /locus_tag="KB909_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBB6838244.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4522..5523
                     /locus_tag="KB909_002247"
     CDS             4522..5523
                     /locus_tag="KB909_002247"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBB6838245.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5520..6881
                     /locus_tag="KB909_002248"
     CDS             5520..6881
                     /locus_tag="KB909_002248"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBB6838246.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6841..7992
                     /locus_tag="KB909_002249"
     CDS             6841..7992
                     /locus_tag="KB909_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBB6838247.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7967..9136
                     /locus_tag="KB909_002250"
     CDS             7967..9136
                     /locus_tag="KB909_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6838248.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9311..10690
                     /locus_tag="KB909_002251"
     CDS             9311..10690
                     /locus_tag="KB909_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6838249.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10971..11200
                     /locus_tag="KB909_002252"
                     /pseudo
     CDS             10971..11200
                     /locus_tag="KB909_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3730 a         1952 c         2498 g         3020 t
ORIGIN      
        1 tttgttttta taaccatttt tattcttatt tttaaaaaaa tatttcgaaa tatactagac
       61 aattcagaaa attttgttta atattattcc aataaaattc aaatctttat caaatgaaat
      121 tccaataaaa acggaaaaaa agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg
      181 gcggagtcac agcaagcaca ttggcagaaa agtataagac acctctgtat gtgtatgatg
      241 aagaaaagat gagacaaacg atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg
      301 atacaaaagt gctttacgcc tctaaagcat tccaaacgat tgagatgctg catttagttc
      361 gtgaatatgg attcgggcta gatgttgtca gtggtgggga aatctatacc gctttgcaag
      421 ctgattttcc tagagatact atctacttcc atggtaacaa caagacgcca gaggaactga
      481 tctatgcact tgaaaatgat ttgttgcata ttgttgccga taatttgatg gaagttgaat
      541 tattagcaga attaagccaa cgctatttaa aaaaaatctg tatcatgctt cggttgaatg
      601 tcggagtaga agcacatact catgaatata tcgtcactgc gcatattgat tcaaaattcg
      661 gcatgagcta tgaaagtaaa gagtgccaac aagcccttca gttgataaaa gaaagcagct
      721 atctagagtt agaaggattt catgctcata tcgggtcaca aatttttgat gttactgctt
      781 ggttagctga aatcgacaaa ttgacgaatt acttaaccga ttttgaccaa cctctttcct
      841 tgaatcttgg cggagggttt gggattcgtt atacacaaaa tgatcagccg atcccagtcg
      901 aagaggcact aaaaaaactg attgaatata cggaagaagc tttggaaaaa cgaaaactga
      961 ccattcgtca attactgatc gaaccgggta gaagtattgt tggagaagct ggtacaacac
     1021 tatacacgat tggtttcatc aaaaagacac cacataaaaa atattacttt gtagatggcg
     1081 ggatgacaga taatatccgt ccagctctgt atcaggcaga atacgattgt gatttagcag
     1141 caaaactgtc ggaagaaaaa acagagaaag tgacgattgc aggaaaaatg tgtgaatcag
     1201 gcgatgtggt aattaaagaa gcttatttgc cgaaagcaga atcgggtgat cttttagctg
     1261 tttattccac gggagcttat ggatactcga tgagcagcaa ctacaatcga gcgacacgac
     1321 cagcagttgt ttttgtcaat aatggccaat caagactgat tgttcgcaga caagcatttt
     1381 ctgatctact aaggggggaa gtttcctatg atccttcata aatataatgg ctgcggaaat
     1441 gattttatct tattagatta cgcagaagac acagattata gtcaattagc cgcttcttta
     1501 tgcacaaaag aaaaatatga tatagacgga ttgatcgccg taaaaatcga tccgttggaa
     1561 atgatctatt acaacaaaga tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt
     1621 tttgctcgat acgtaaatga tcagaacatg atgaatgaac aggaattcaa cgtagagaca
     1681 ttagcaggca caagaaaaat tacggtgttg gatccctcac ctttttattg cagcgtagat
     1741 atgggagtgc cagatgattc tccggaaaaa atcaaagcta atcaaactta tccaataaaa
     1801 aaccaggaaa tagagatcaa tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg
     1861 attcataccg ttgtttttgt tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa
     1921 ctgatctgtc atcatccttt gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc
     1981 aatgaacaag aattgatcgt ccgtacctat gaaagaggag taggttggac acttgcttgc
     2041 ggtacaggtt gctgtgcctc ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat
     2101 caggtagttg ttcacttgga acaaggagac ttgatgatct ctggtgagga tgcgatacaa
     2161 atggctggcc cagcagttca tgaatggaca agaatattgg aggaatgaag atgataaaag
     2221 gttcgatcgt ggcgctgatc acgccgatga atgaagaggg atcagtagat tatgctggtt
     2281 tggaaaaatt gatccaattc catttagatg aacaaacaga tggattatta gttttaggta
     2341 caacaggaga atcttctacg ctcacacaat ctgaggagga gcagatcctt caactgacag
     2401 taaagaaagt ggctggccgt gtgccggtga ttgcaggagc tggaacgaat aatacgaaag
     2461 aaacgattga aaaagcgaag cattttgctt ctttgggggc agacgcactt ttggtcatca
     2521 ccccttacta caacaaaaca agtgatgcag gactagctgc tcattttaca gcaattgcag
     2581 aagcctcacc gattccgctt attttgtata atgttccttc tagaacaggc atgtcgattc
     2641 caatccatgt attagtaaat ttagcagaac atcctaatat cattggtttg aaagaagcct
     2701 caggagatat ggcttatgtg atggatgccg ctcggttgat tggagaagaa ttcttccttt
     2761 acagtggaaa tgatgatttg atcctaccag taatgagtgt aggaggaagc ggtgtaataa
     2821 gtgtatgggc gaatatccaa cctaaaatag tccatgaatt agtaaaagat acgcaggacg
     2881 gaagatggca gcaagcaaaa gaaaagcaat taaatgcact tgaactgatc catgccttgt
     2941 tcagtgagac caatcctatt cctgtcaaag cagccatgtc attattagac ttaccttccg
     3001 gacctctacg cctgccttta gtttctcttt caaaagagaa aaagaaacaa ttagctcagc
     3061 ttttgttaaa agaaaggacg gttgaaaaat gaaaatcgga ctgattggca gtggacagat
     3121 gggaaataga gtcgaagaag ttgcacaaga aagaggagat acggtccttc ttttacggac
     3181 ggcacctaaa gaagcaacta cgcttgcttt tacggaactg ccagaactgc ttattgattt
     3241 ttctcatcca gataatttag agaaaatcct ttcgtatagc ttatcatatc aacttccgtt
     3301 agtcattggc acgacaggtt atacacaatc acagttccaa gaaataaaag aacatgccaa
     3361 acatgtacct gtgatgtata gtgctaattt ttcgttcggc atcatggtga tgaatcaact
     3421 aatcaagcaa gcagctgcaa tgttgcaagg ctggcagatc gaactgattg aaaaacatca
     3481 tagtcgtaaa aaagatgcac catctggtac tgcaaatatg ctgcttcaaa caatccaaga
     3541 agtgcaaaag ctgcagcccg tatacaactg gcaagggaaa aaaagagaag aaaaccaaat
     3601 tggtgtacac agtattcgtg caggttcttt acctggtgaa catgatgtat tgtttgctgc
     3661 tactgatgaa atatttacga tcaaacatga atctttttct aatcgaatct ttgctgcagg
     3721 cgcagtagaa gcagcggact ggttgaaaga tcagtcacca ggttattaca aattagaaga
     3781 tttattaatg gacaaagggg tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt
     3841 caaacggcat ctaaaaagac gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa
     3901 tttaaagaaa gtaaagtttt tggtgaagga agcagcttcg ttgtttttgg tgactatgag
     3961 acgattgctc cggttttaga agctgaatca gaaaaaatca ttgaaatcga aatcgaaact
     4021 gctgcaagat acagcgcagt tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa
     4081 ccaggtgcta ttatcagaga tcaagtgtca atcggcaaca atgccgtgat catgatggga
     4141 gcgattatca atattggtgc agtaatcggt gaaaacacga tgattgatat gggtgctgtc
     4201 ttaggtggac gagcgacagt gggcaaaaac tgccatattg gtgcaggagc tgtcttagca
     4261 ggtgtgatcg aaccagcatc ggccaaaccg gttatcgtag aagacggcgt actggtaggt
     4321 gcgaatgcag tgattgttga aggtgtccat atcggaaaag atgcagtcgt ggcagcagga
     4381 gcagtggttt tagaagatgt ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta
     4441 ttaaaaataa gtgatgatca gacaaaagaa aatacagcat tgattgctgc gttacgcgaa
     4501 ttatagagga gatggagaaa aatgcgcgaa atagatacct gtattgtggg ggcaaccgga
     4561 ttagtcggcc aaacgatgct caaagtgtta gaagaatatg attttccagt aggacgattg
     4621 aaattattag cttcaaaacg ttcagccggt aaagtttgtg tattcaagaa aaagaaacac
     4681 actgtacagg aattgacaga aacttcattt gaaggatatg atttagcgct attttctgca
     4741 ggtgcttctg tatccaaaga gtttgcgcca atcgcacgaa gtcagggact atttgtcata
     4801 gataattcct cagcatggcg ggaagattcg gatattccat taatcgttcc agaggtcaat
     4861 ctggaagact atacattgaa tcggctgatt gcaaatccaa attgttcaac cattcaagcg
     4921 gtacttccgc ttaaagcttt acaagaagcc tttggtatcc agcgagtcaa ttattcgacc
     4981 tatcaagcag tttctggttc cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat
     5041 gacgaggaac cagttttgta tccttataat attagccaaa cggtgattcc ggaaatcgat
     5101 cagcctttgg aaaatgggta tacaaaagaa gaacagaaaa tgataaatga gacccgtaag
     5161 attctgcatc agcctgcttt gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat
     5221 ggacatggag tctctgtggc agttcaactg caaaaagagt ttacgacgga agaaattaga
     5281 gagtgtctca gccagtttcc agggattcaa ttagaagatg atctagcagc acataaatat
     5341 ccgacgagca ttcttgctag aggaacagat atggtttatg ttgggaggat cagaaaagac
     5401 acttctttag agaacggatt gttgttctat acgactgccg ataacatacg caaaggagcc
     5461 gctgcgaatg ccgtacagat tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga
     5521 tgagtaatac gctgaaagta gcgaaattcg gcggaacatc gatgtctcat gaagagcaat
     5581 tcaaaaaagt ccgtacaatt gttctttcag atcccaatcg ccaagtgatc gttgtttctg
     5641 ctttaggcaa acgtacgtca gatgatgaca aagtaacaga cttactttat ttgatttatg
     5701 cttaccttca gcatcatgtt gattggacac ccctttggaa aaggatttgt gatcgtttca
     5761 ttcaagtaag agatgttctt gccctgcagt tacctattga agatgaacta gcacgcatac
     5821 agaaacaact ggaagacgaa aagataactg aagattattt agtaagtaga ggtgaatatc
     5881 tgactgctca actgatggct gagtatcttg gttaccagtt tattgacgca aaagacctga
     5941 ttttctttga ctatgatggg aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag
     6001 catttaaaag atatccgaaa atggttgttc cagggtttta cggggcgaac cctgcaggaa
     6061 aagaaaaatt attgggccgt gggggaagcg acattaccgg cgcgatactg gcgaagatgt
     6121 tgcaagcgga aagttatgag aattggacgg atgtttcagg aatcatgatg gctgatccgc
     6181 gaatcatcga tcatcctaaa atcatcgagg aaatctcttt tagagaactg agagagatgg
     6241 cttatatggg ggctaacgtt cttcatgaag cagctgtttt cccagttcaa gaggctgata
     6301 tccccatcca aataaaaaat accaatgatc ctttcgctca agggacaaaa atatcgaatc
     6361 acgaaataga aaaggaaaat ggactgacag gaatagctgg acgcaaggat tttctttcca
     6421 tcactttatt caaacgtcat atgtccgatg aaatcgggtt tatctggaaa gcaatgagca
     6481 tttttgctaa acatgagata tcaatcgaac atattccttc agggatcgac aatatcggag
     6541 tgatcgtctc agcagaagcg attgccgata agttatttct catcacgaaa gaattaaaag
     6601 aaacacttgg cgtggaagaa atcgtcgtga tcgaagactt agctttgatc tctgtcgttg
     6661 ggggtccgca taaagaattg attggattat ctgggaaagt gttatcgata ttgaacaaat
     6721 tagaaattcg cacatcgatc ttatcacaag gagcacagga gttgaatctg atcatcggtg
     6781 taccgaataa tcaatatgaa acagtagtga agggtatcta tgaagggatg gtgaatacgg
     6841 atgctgaaag aatatcgaat ggcactccat caaattcctg aaatcgggtt tcatgaattc
     6901 aagacaaaaa aatatttata tgaacaagta aaaaacagcg aggccgttat ccatgaaatc
     6961 ggcgaaacag gactactcct ttattttgat aatcagcaag aagaaacgat tgcttttcga
     7021 acagatatcg atgcactgcc agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat
     7081 gaaggttata tgcatgcatg tggtcatgac ggacatatgg cgatgctttt agggttgact
     7141 gactttataa ctaaacacat tgaggatctt atttataatg tagtactgat ctatcagcca
     7201 tcagaagaaa tttccggtgg cgcacaaagc gttattcagt caggattgtt ggataaatat
     7261 gaagtacaag caatatttgg ctttcatcta tggcctggac tagctaaggg agaagttttc
     7321 tctcgaccag gacctttgat ggcacaaagc agtgaaacag acattatcat taaaggccag
     7381 tctgcacata ttgcttctag tgaaaaagga atcgatagtc tggaggcagc tgtacgattt
     7441 ttgaagaatg tttatgattt tgaccggcaa ttaccggcag agtggaatca tctaatgaaa
     7501 tttggccaaa tccaaggtgg aacgatccga aatgttttag ctggagaagt tattgtatcc
     7561 ggaagtatcc gttcttacag ttcagatatg caaaattatt tgaagagggg attagaccat
     7621 ttagcagaac agtttcactc tacagctact atttcttttc gctataatga cggctatcca
     7681 gctgtaatca accatagagg cttatatgca gcactgttag attcaaacaa actacatgaa
     7741 ttagatgctc cagttcttca agccgaagat tttggcatat atacgcaaca atatccatgt
     7801 gtatttttct ttttaggtgt cggtgatacc cctgctttac atgatccgac gttcgatttt
     7861 gatatggatg ttttagaaaa tggtgtagaa tggtacaaaa cgattctttt tacagaaaat
     7921 cttcttgtaa aaatcgatag cagttcaaaa gaggagcgag taaataatga tgaatttatc
     7981 caatcgattt agtcctaggc tttctagaat agaagtatca aaaatacgac aattcgatca
     8041 gcaaatatcg tcgataccag atgtgatcaa actcaccctg ggagaaccgg attttccaac
     8101 tcctgaacat gtcaagcaag caggaatagc agcgattgaa gaagactttt ctcactatac
     8161 cggaatgaga ggattagagg aactgcggga agcggcttgt atatttcagc aacagcgtta
     8221 tggattaact tatgatccgc aaacggaagt tttgacgaca gttggtgcaa cggaagcgat
     8281 tgcctctgcg ttgttatctg ttttggaaga aggagacaag gttcttattc cagcgcctgc
     8341 ttattcagga tatcagccat tagtggaact agctggtgct gaattgatcc cgatagatac
     8401 ttctgacaca gggtttgtct gtcagccgga acaatttgaa cgagcatttg aacaatatgg
     8461 atcagctgtc aaagcagtca ttttaaacta tcctaacaat cctactggga cgacattgtc
     8521 tgcaaaacaa ttgaaagcaa tcgctgaggt tttaaaaaaa tatccggtat ttgttataag
     8581 tgatgaagta tatgctgaat tgacttatag tggaacgcat atgtccatag ctacttatct
     8641 tccagaacaa acaatcgtga taagcgggtt atccaagtca catgcgatga ctggttggcg
     8701 agtgggcttt atttttgctc aaaaagccct tattgacgaa ctaattaaag tccatcaata
     8761 tctggtgact gccgctacaa cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg
     8821 ggtgaaagat agcgagaata tgaaagagca atatcaaaca cgaagagact atctggtcca
     8881 gcaattggcg cctttaggat ttgaagtgac ccagccaaac ggtgcatttt acttgttttg
     8941 caaactccca gctgccattc aaactgactc ttggcagttt tgtgtagaat tagcggaaca
     9001 ggcaaaagtt gcgtgtatcc caggaattgc atttggccca gaaggagaag gttatatccg
     9061 gatttcttat gctagcagca tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt
     9121 tttaacagaa cagtgattca tagattttat caaaaaaaca atcgttaatt ttgcggtata
     9181 ttctgcaagg agacgattgt tttttaaatt tagttcaaat gaacgcgttt cttttgattc
     9241 ataactaatg taatgttaag tttaaattgt ttagaatgat tttaaaagaa tattcaagga
     9301 ggtttcatca atggaaaaaa tcaaagttgt cattgtaggt gcatctcatg gagggcatca
     9361 atcgatcttg gaactattga cacgatacgg tgaaaatgta gatatcacgc tatttgaagc
     9421 aggagactat atttccttca tgtcatgtgg tatggagctg tatttagaag acaaggtaac
     9481 agatgtaaat gatgtacgta atttcagacc agaaaacttt ccgcaatcca atgttcatat
     9541 tttaaataat cacgaagtaa aaacgatcga tgccgataaa aaaacagtaa cggttactag
     9601 cgcatcagat aacgaaacaa aagaatatcc ttatgacaaa ttgattttga gttctggtgt
     9661 caaaccaaac aatctgccag taccaggagc agatctagaa aatgtctact tgatgcgtgg
     9721 atacaattgg gcaaccaaaa tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc
     9781 tgtcgtaggt gcgggttaca ttgggatcga agcagcagaa gcaagccgaa aagctgggaa
     9841 agaagtcgta ttgcttgatg tgatcgatag acctttaggc acttatttag atgctgagat
     9901 gacagatatt ttagaacaac acctaaatga aaacggtatt gaagttttga caaatgcaaa
     9961 aatcgaagct tttactggta acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat
    10021 cccagcagat ctagtcattc aagctgccgg tgtgaaggca aatacagaat ggttaaaagg
    10081 gatcgtcgac ttagatgaac gtggctggat ccaaacaaat gaatacttgc aaacgaatct
    10141 tccagatgtg tatgcagtag gagatgctac acttgcttat tctatcccag cacgcaaaaa
    10201 aatgccgatc gctttagcga ctgttgcacg tagagaagca cgttatgtag taaaacatct
    10261 ttttgaagaa gtaccaaaca aaccgttcgg cggagtcgta ggttcctctg cattaagtgt
    10321 ctttgactat cattttgcag caagcggatt gaatagcttt acagcagcaa aagcaggagt
    10381 agatgtacga gtgtcttatt atgaagatac gttacgacca aaatatgtac cagaagaaca
    10441 aggaaatcca aaagtgtcca tccaattatt ctcggatcca atgacccatc aattgctagg
    10501 aggagcagta ttatctacct atgatgttac aggtcaagga aatgtattgg cactagcgat
    10561 ccaaaacaaa ctgactttag aagaactagc agaagctgac ttcttcttcc agccaggctt
    10621 tgaccgacaa tggagcatgt tgaatctagc cgctcaacaa gcgttaggag aagaaccatt
    10681 tgtagaataa gaaaacgaaa tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag
    10741 taataagaac agccaagtaa aaacagcttc ttatgttttt aacttggctg gacttattac
    10801 cgcagatgca agcttttgaa caccgtttat tttcaaaaaa gggactgtga cacgatttgt
    10861 gtaccgaccc ccaaaagtta gaccaaaaaa tctaactttt ggaggtcggt attttttatg
    10921 gttaaatata cttttgaact taaattaaag atcgttcatg attatttgga tggcaaaggc
    10981 gattggaccg taaaaatcca gatcaagaga ttgaagcgga aatgcttaaa attcgggaga
    11041 agcacaagga ttatggctgt ttacggatga ccaatgaact aagaaaccgc ggtttctcta
    11101 tcaataaaaa gaaagttcag cgcttgatca agaagctagg aataaaagta acggcataca
    11161 cgcgtaaatc acgtcgctac aattcttatc gaggaaaagt
//
LOCUS       DADVXK010000093        11007 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.094, whole genome shotgun sequence.
ACCESSION   DADVXK010000093 DADVXK010000000
VERSION     DADVXK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.094"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            84..1016
                     /locus_tag="KB909_002253"
     CDS             84..1016
                     /locus_tag="KB909_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838250.1"
                     /translation="MIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEEDK
                     KSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEVVY
                     KNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYLLS
                     EKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFVVS
                     ESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQNGL
                     ETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            1237..3000
                     /locus_tag="KB909_002254"
     CDS             1237..3000
                     /locus_tag="KB909_002254"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBB6838251.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            3084..3542
                     /locus_tag="KB909_002255"
     CDS             3084..3542
                     /locus_tag="KB909_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBB6838252.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            3651..4334
                     /locus_tag="KB909_002256"
     CDS             3651..4334
                     /locus_tag="KB909_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6838253.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            4481..5095
                     /locus_tag="KB909_002257"
     CDS             4481..5095
                     /locus_tag="KB909_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBB6838254.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            5111..5317
                     /locus_tag="KB909_002258"
     CDS             5111..5317
                     /locus_tag="KB909_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838255.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            5856..6413
                     /locus_tag="KB909_002259"
                     /pseudo
     CDS             5856..6413
                     /locus_tag="KB909_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            6471..8510
                     /locus_tag="KB909_002260"
     CDS             6471..8510
                     /locus_tag="KB909_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBB6838256.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(8619..9770)
                     /locus_tag="KB909_002261"
     CDS             complement(8619..9770)
                     /locus_tag="KB909_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBB6838257.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(9924..10454)
                     /locus_tag="KB909_002262"
     CDS             complement(9924..10454)
                     /locus_tag="KB909_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6838258.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(10553..10903)
                     /locus_tag="KB909_002263"
     CDS             complement(10553..10903)
                     /locus_tag="KB909_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBB6838259.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
BASE COUNT         3964 a         1876 c         2153 g         3014 t
ORIGIN      
        1 acatcttgct agctttagta cgttatgtca attgggaagg ctatgaaaat aaaaatccgt
       61 atgtagaaga agcttgtaac gagttgattg attatgtaga gactcatttt tttaaaagaa
      121 gatattcgga agatgaaaag tcctttatca tacgaggaat agagatcgca atcggaagaa
      181 aggcatttcc ccttggactg aaagaagaag ataagaaaag cgcagaaacg aagccgttat
      241 ttcaattagt ctgtcaagga ttggaagagc aaaaaggaat tctagactta caagaagaag
      301 atgtctatta tattttttct ttgttcaaca gtagaaatta taccaatgag aacatggagc
      361 tgttaagaaa agatttcgaa gttgtttata aaaattttgt tctcaatgac ctatcactga
      421 atgaattgat tttacagatt attagtatcg ctgaaatcga cgatgcagaa aattttattt
      481 tcaagcaatc ctttttacaa tttgtccgta cgttgtgggc agatggacaa gtatttttac
      541 cggaaaggat ctatcttcta tcagaaaaag aacaacttct gtacggaaaa attgtagaaa
      601 tattggaaga gtggaaaaag aaaaatcaaa tccaactaag atggaatgaa aatttcattc
      661 gaaaattcgt caaaagtctt tctttgatca acagtgaaca agcggggaga caggaaatag
      721 aaatttttgt tgtttcagaa agttcagtca aacaattttt ttatcgaacc caatttcatt
      781 tgtatgcgga agaaggcatc gctgaaataa atcctatttt atttcgttca ttagaagaat
      841 tgcctgatga atgtctatgt gcgaaaaaaa gagtggtttt gtgcgatgct gctagctatc
      901 aaaatggatt agaaactgaa aagacaaaga tctatccaat ctcattaaaa ggtgcaaaca
      961 tccatttgta tcatattgct caggaacttc acctattaaa aaaacatatt tcttgatgag
     1021 accttaatta ggagaccttc tacaaagctt tttaattgtc tgtagaaggt ttttatttga
     1081 gtcctgattc gtgcgaagat ctacttatat aacaagcttt ctctgaaatt tttttaaaat
     1141 gctattgact tagagtcaac tctaagtagt agaatagata aagtgtaaca aatctatttt
     1201 cattaaaaga agatagtacg gaggagagaa tgtattatga gtacagtatt acatgtattg
     1261 gatgcaatca atagccccgc agatgtcaaa aaattatctg ttgaggaaat gaaacagttg
     1321 gcagaagaga tgcgccaaaa aatcttgcaa aaggacagcg atgtaggtgg gcacgttggt
     1381 ccgaatctag gtgtagtaga attaacgatt gcgtttcatt atgtatttga ttcaccaaag
     1441 gataaaatcg tttgggatgt ttcccatcag tcttatggtc ataagctttt aactggtcga
     1501 aaaaatggtt ttgaaaaagg acattaccgt gaagtgagcg gatattccaa ccaacatgaa
     1561 agtaaacatg actattttac agtggggcac acatctacat ctatcagctt agcaacaggt
     1621 ttagctaaag cgagagatct gaagaaagaa tcaggaaatg tggtagcatt tatcggtgac
     1681 ggctccctaa gtggtggctt agcttttgaa ggattgaaca atggtggtgt tttacaatcc
     1741 aatctaatcg tattagtaaa cgataatgag atgtctattg atgagaatca tggcagttta
     1801 tataaaaact tagctgagct tcgtcaaacc aacggtaaaa gcagcaataa cctatttaaa
     1861 gcaatgggat ttgattatcg ttacgtggat aatggaaacg atctggaaac ggtgatccgt
     1921 ttatttgaag aagtaaaaga tattgatcat ccgattgtac ttcacgtcca tacggaaaaa
     1981 ggtcgcggtt atcagccggc aatcgataat aaaatgaaat atcattggca tgtaccattt
     2041 gatctgtcca ccggggaggc aaagcaagta acttctggag aaacatttaa tatgatcatc
     2101 atggattatt tggataagaa aatgcaaaca agtacagctc ctattgccgc agtcaatgca
     2161 gcgataccag gcgcctttgg actgaaaaca ttccaagaaa aacatccaga tcattatttt
     2221 gacgtgggga tcgctgaaca gcactctatc actttcgctt ctgctttggc ttctcaggga
     2281 gtacgtccag tcgtcttcca atcaagtact ttcttgcaac gggcatatga tcaattatca
     2341 catgatttag cgatcaacga gaatccagtg attattttag tcggtggcgg aacgatctca
     2401 gctagtgacc gaacacacca aggaacattt gacattcctt acttatcaag tatcccgaac
     2461 atcaaatatc ttgctccagc aacaaaagag gatatgatct ctatgctaga ttgggcgttc
     2521 gaacaaacag cgcagcctgt agcaatccga attcctacac atggtgtaga acatggtaca
     2581 gctatcgcaa atgattatag tattccagcc tatcaaacag taaataatgg aggaaaagta
     2641 gcaattttag ctttaggcgg ttttcttgaa ttaggaaaag aaacagtaaa agcttttaga
     2701 aaaaaaggaa tcgaagcaac gttgatcaat ccaggaacga tcacagaaaa tgacgtagaa
     2761 acattagata aattaaaaga aacacacgaa ttagtcatca cattagaaga tggtagtttg
     2821 tcaggaggat ttggcgaaaa tatcagtcgt tattatggtg attcttcaat gaacgtatta
     2881 aattttggtg cagagaaaga attcacggat agcgttcctg tagggcagct ttatgaacgt
     2941 tatcatttaa caccaaaaca aatcgttgaa gatagtctgc gtgtcttgaa tattcaataa
     3001 ttcattatgc tcaccatcca gataattgtt tatactagta tctggatggt tttttcatta
     3061 taaaaagcaa aggggtggat gttatgtatc agcaagtaga agaatatgtc aaaaagttcc
     3121 aagaaaaata tcctagttat caatcagaaa aattaggttt cttttcattt ggggatacag
     3181 aaaaaatggc agacgagttg agcgaactag ttgtaaaaaa gataaagact ggtacatcaa
     3241 gtggttacga tctgtataaa caagagaatg agcctttacc aaaagttggt caattagacg
     3301 tggtcctgaa tggaaaaaat gaaccagttt gtatcatcaa aaatataaat gtgaccatct
     3361 tgccttttag tgaagtcacg aaagagcatg cttggaaaga aggagaaggg gatcggacat
     3421 tagcttattg gcggaaagtc catgctgagt tttttaaaca tgcttataaa gaagcgttga
     3481 acatagaatt tacagaagag aagctggtcg tatacgaaga atttgaagta attttctttt
     3541 agtaagaaag gtctgctgaa agaaatagct cattattgtc tcctgaatag aaaagggtta
     3601 catttttata tgaagctgta tttttatata acattactgg aggagatatt gtggatacac
     3661 tggaacaaat caaaggcgga gtcgtcgttt cttgtcaagc tttggaaaac gagccgctac
     3721 acagttcttt tattatgggg agaatggctt tggctgcaaa agaaggcgga gcagttggta
     3781 ttcgagcaaa tacgacagaa gatatcaatg aaatcaagcg aatcgttgat ttaccggtaa
     3841 tagggattat caaaagagat tacgatgggt cagaagtgtt tattactgcg acagaaaaag
     3901 aagtggaaga acttttggag acgcaagcag aaatcattgc actggatgca acttctcgta
     3961 aacgtccgac agaaaaaaca actgctgaac ttgtccaaat gattcacgaa cacggtcggt
     4021 tagctatggc agatatttcg acttttgagg aagcgcttca agcgcaagaa gatggttttg
     4081 atcttttgtc tacgacttta gcaggctata cagaatattc acgaaagacg cagacacctg
     4141 attttgattt attgaatcaa atcatagaac aagtcgatat cccagtaatt atggaaggac
     4201 atactgactc tcctgaacaa gtagagaaag catatgaatt aggtgctttt tcagtcgtag
     4261 ttggatctat tatcacccgt ccgcaattga tcactaaaag atatgtcgaa gccgcaagta
     4321 aagcaaataa ctaaaaaaca cgcacggcac agattcttga caaaaaagaa aaattgatag
     4381 atagtttaaa gcagattcta agaagatgaa aaaagcatta cttttcattt tgtcttcaag
     4441 atctgctttt taacgaattt tatagaaaga aggcgaaacc atgtttgaac ggagtccttc
     4501 agaattgaca gaacgtgaaa attacaagtt gctgattggt tcagtcatcc ctagaccagt
     4561 agcagtagta acgactaaat cagcaaaaga tatagtgaat atcgcaccct tcagttactt
     4621 caatatcgtc agttcgaatc gacccatctt atccttggcg atccagagaa aacaagatgc
     4681 agtaaaagac acagcaaaga atattcttga gacaagagaa gctgttatcc atatccttga
     4741 tgaggacaac gtagaagaag taaataaaac agcagccaat ctgcctaatg aggaaagcga
     4801 actgtacctg actgacttga ctttaactga ttcagtaatc atttcagtac cagcattgac
     4861 agaagcaaaa gttcgttttg aaacatcctt atatgaacat gtcgagatac ggaataaaaa
     4921 taaagtaaca gctgatttat ttttgctaga agtacagaaa tatcatttaa atgaaacagt
     4981 ctatgatgat aagacaggaa ggatcgatcc aagaaaattg aatgctgtaa gccgtttggc
     5041 aggaaatgat tatgcagcaa taggagaaat tttcacgatt gcacgtcccg aataaaaagg
     5101 agcactagtt atgttaaaaa taagctataa accatcgaca gattcaaaag aaatgaaaaa
     5161 agaatatgaa acagtgaatg attttctgca agggcagtac ttagaagttc cgccattgca
     5221 agaccatttt gtcgttacta ctgttacttt agatggtaag gaaatagaaa tgccagatca
     5281 aacgattagc ggattgttta attactttaa caaataaata tttattccga aaagtgaaaa
     5341 aacatataaa aaaacacata aaactaaaaa attatcaaag aatcctggtg caactgaaag
     5401 aatttgcaac gggattcttt caacttattt gttatttttt tctaaaaaat attaaagatt
     5461 gttaaatttc actatttcat ttcaaattcc attgcctaat cattaggaaa agtctatcat
     5521 gaactcgtaa atagaatata gtaataacct tgttaggtga ggctcctata caaacatagg
     5581 ctgttgccca gaaacgtcga aagtcgccaa tgggtaaaac agaaactgtt ggattaaggc
     5641 tttttccaat agctaagaat gttttcttta cgttgtatag tgctaaaact cggacgatga
     5701 gatgatgcta ggtcagaatt cttgttcgaa aaggtttctg accttttctt tatatttttg
     5761 tgactgactt atttgatgag acaaactcgc tcctcacctg acaagtggat tgctgtgtga
     5821 ggaggagatg cggtgaaaaa agatcgattg gtggaggtcg ctcggattca cttctggttg
     5881 cacaatacaa ccagaaaaca caacaagcaa aactgatctc tatcatgaga gattcatatg
     5941 tcgatattcc aggttacgga atgaataaga taaatgcagc ttactcttat gggggagttg
     6001 atttattaaa tcaaacatta aaggaaaatt tcaaatttga agctccctat tatgcaagta
     6061 tcacatttca agattttatc gattgcgtta atgaactgtt tcctggtgga gtcaagatcg
     6121 atgcagaaaa atctctagat ttagatggcg tatatataaa caaaggagag caagtgatgg
     6181 atggtaatac tttactccag tatgctcgat ttcgggaaga caaagaagga gacttcggga
     6241 ggatcagaag gcagcagcaa gtgatcaaag ctatctctca gcagctgaaa gacgtaactt
     6301 caatattcaa gctacccaaa gcggttggga aattacttgg tagtatccaa acgaaccttc
     6361 cagaaagtgt gcttctggat tgtggtatgg atttcctcaa agacatatgt tagaataaac
     6421 aggtataaat agtgaaataa aggaatgaca agcaagagaa ggaggaaaaa atgaaaagaa
     6481 gtgacaagca cggcaaaaat cgaacaggcg cttatattgc cggcgcagtg atcttaatag
     6541 cagctgcggg tggcggttat ttttactacc agcactatca agaaacccaa gcagtagaag
     6601 ctggagaaaa gacagttgag caatttgtcc aagctttgaa caagggagat tataacaaag
     6661 ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc attatctgaa aaagagatct
     6721 tagatcaata ccagaatata tacggtgctg ctgatgtcaa aggacttcag atatcgaatc
     6781 taaaagtaga taaaaaagac gattctactt acagtttttc atataaagca aagatgaata
     6841 cctcattagg tgaattgaaa gatctttctt ataaaggaac attagacaga aatgatggtc
     6901 aaaccacgat caactggcaa cccaacttgg tttttccaga aatggaagga aatgacaaag
     6961 taagcctgac cacacaagaa gcagcaagag ggaatattat agatcgaaat ggtgaaccat
     7021 tagcaacaac aggcaaacta aaacaattag gagtcgttcc aagtaaactt ggagatggag
     7081 gcgaaaaaac agccaatatc aaagcgattg cttcctcctt cgacttaaca gaagatgcta
     7141 tcaatcaggc gatttcacaa agctgggtac aacccgatta ctttgtccca ttgaaaatca
     7201 ttgatggagc aacgccagaa cttccagctg gagctaccat tcaagaagta gacggcagat
     7261 attatccttt gggtgaagca gctgctcagc tgattggtta cgtgggagat atcacagcag
     7321 aagatattga taagaatcca gaattaagca gtaatggaaa aatcggtcgc tcaggtttgg
     7381 agatggcttt tgataaggat cttcgtggga caacaggtga gaaattaagc attacagatg
     7441 cagacggtgt agagaaaaaa gttctgatcg aacatgaagt tcaaaatggc aaagatatca
     7501 aattgacaat cgatgcgaag gcacaaaaaa cagcttttga cagtctagga ggaaaagctg
     7561 gatcaactgt tgcgacaacg ccaaaaaccg gtgatcttct tgcgcttgct agctctccaa
     7621 gctatgatcc aaacaaaatg acaaacggga tctcacaaga agattacaaa gcttatgaag
     7681 aaaatcctga acatccattc atcagccgat ttgcgacagg ttatgctcct ggatctacgt
     7741 ttaaaataat tacagcagca atcggtctcg acaacggcac tatcgatcca aatgaagtgt
     7801 tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg gggatctttt aaaacaacgc
     7861 gtgtcagtag tgatgtatca caagtagact taaaaactgc tttgatctat tccgataata
     7921 tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa atttcgtaca ggcttagata
     7981 aattcatttt tggtgaagac cttgatttgc caattagtat gaatccagca caaatttcta
     8041 atgaagatag ctttaactca gatatcttgc tagctgatac tggatatgga cagggcgaac
     8101 ttctaattac tcctatccag caagcagcaa tgtattctgt ttttaccaac aatggcacac
     8161 ttgtctatcc taaattgatt gcagataaag agacaaaaga taagaagaat gtcatcagcg
     8221 aaacagcagt acaaacgatc gtgccagatc tgagagaagt tgtgcaagat gtaaatggta
     8281 cagcacattc tctttctgct ttagggattc cgttggcagc gaaaactggt acagcggaaa
     8341 tcaaagaaaa acaggatgta aaggggcaag agaacagttt cttgtttgct ttcaatcttg
     8401 ataaccaagg ttatatgatg gtcagcatgt tggaaaataa agatgatgat gattcagcaa
     8461 ccaaacgagc atcggaacta ttgcaatacc tcaaccaaaa ttatcaataa aaaattgctt
     8521 tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt ccttttttca aataaacggt
     8581 tttcacgatg tctctttcac aacttctttt tgatttactc acacttcata aacttttttt
     8641 gtaaaatatt tgagaacaag tggagaaata agtgtactta ataaaatcac gataactaaa
     8701 ggtgaatagt actgtggttc gatcaattga ctttgctgtc caatttgtaa aatgatcaaa
     8761 gccatttctc cacgcgaaat cataccagca ccgaccatca atgaactatg ttgagaaaaa
     8821 ccggcaatct gagcaccaaa ataacctcca agcaatttgg tcaaaatcgc tacaagcgtc
     8881 aatatagaaa taaagagtag ttgttcacta aagtcagaaa aatcaacttc taatcctaca
     8941 ctgacaaaaa atactggtat aaatactgca tatcctaaag cctctacatt gtggtatact
     9001 tcttctttaa cctttgtctg actgacagct atcccagcaa aaaaagcacc aatgacagag
     9061 ctaagcccaa caagatccgc tacgtaagac attcctaaac aaataactag cgatacgatg
     9121 ataatagaag aatttgcgta cactttttct gcaaatgaaa gtaggaaagg cgcaatccat
     9181 ttgactaata agaaaataaa aacaaaataa attagctgtt caatcaaaac aagcggtaaa
     9241 gaagcattgc tagaagcttc ccccgttaga aaagataggc tgaaacttag aactaaaacg
     9301 actaaaatgt catctaccac agaagcaccc aaaattgttg atccttcttt tgtattcact
     9361 acgtttagtt cttttaatac ttctactgaa atactgacag aagttgccgc aagaataatc
     9421 ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt tgcctgtcaa ccagccaaaa
     9481 acaaccggga agatgatccc aagcaaagca acgaacatac caggtcggaa atattttttc
     9541 aaaagagata aatcactttc cagaccagct aaaaacatta ataagaacac accaatctcc
     9601 gaaaagtcat ggactagaat atcaggtttg acccaattca atccagcttg gcctagcaaa
     9661 acaccaacaa gtaattgtcc aatcactgct gggataccta atctccgcga gatatgtgag
     9721 ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa taaattccat tctcatcatt
     9781 cctttgtata aaatatagcc cgaacttagc ataacataca ttattgaaaa aataggaaaa
     9841 tatactcaca aaaaaaccaa caatccaaaa gatttttttg gattgttggt ttttatacgg
     9901 tctattttaa taactaaaaa tgattaacgt atagtcattt ttcttattct gatgaaattg
     9961 ataatctcct ggatgcccat gaaaatcaaa ataaagccga atatttggaa tagaagcatc
    10021 aaacttttga atggattgaa caataagacg aatccgccaa tcaacaacag aatactacta
    10081 taaacactcc aacttttagc ttttgtattc atgctgaaga acaactggaa caagctgttg
    10141 atgataacag ctaatccaag aagaatcggc aggatagaaa cgattgcagg tgcaaaagca
    10201 tagacgatca gagctaagat caggaaaaaa agaccactga acagaccgat actccaagaa
    10261 cctgttttcc ttttaaaacg gtaagcctca aaaagattca acaacccaag caaaacaaga
    10321 taggcggtga tcagataacc gataaaatga aaaacagcag aagggtttag cacaatcgca
    10381 atcccagaaa taatataaac agcagctctt aataaggcgt atttttgaat attttgttta
    10441 atcgtctcaa acatataaga aaacctcctt tgacttattt taacgtgaac tagtcatttt
    10501 accaaattaa atgttacaaa atgagcgaag gagaagaata tctctggaaa aatcaacttc
    10561 tgaggatctt ttccattttt ttgccttttg ctagctcatc gatcatttta tctaaataac
    10621 gaatttcttt catcaagtta tcctcgatgt cttctactcg tacaccacaa acaacacctg
    10681 taatcaagga acgtgaagga ttggggacag gggcttccgc aaaaaattgt tcgaaagtca
    10741 cttgtttttg tagttgatat tctagttctg tttgggaata acccgtcagc caacaaatga
    10801 tttcatctac ttcctctttt atacgatctt ttctctccgc ttttgctaca tacataggat
    10861 aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc cataatcagt cacctttctt
    10921 tttttcaaat tatttactac ttatagtata taagaaaaag agaagaaaaa gcgattattc
    10981 aaaaaaacaa aaaggattgt gacaaaa
//
LOCUS       DADVXK010000094        10819 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.095, whole genome shotgun sequence.
ACCESSION   DADVXK010000094 DADVXK010000000
VERSION     DADVXK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.095"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            12..84
                     /locus_tag="KB909_002264"
     tRNA            12..84
                     /locus_tag="KB909_002264"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="KB909_002265"
     tRNA            88..160
                     /locus_tag="KB909_002265"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="KB909_002266"
     tRNA            168..249
                     /locus_tag="KB909_002266"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="KB909_002267"
     tRNA            267..339
                     /locus_tag="KB909_002267"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="KB909_002268"
     tRNA            351..422
                     /locus_tag="KB909_002268"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="KB909_002269"
     tRNA            439..524
                     /locus_tag="KB909_002269"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="KB909_002270"
     tRNA            535..608
                     /locus_tag="KB909_002270"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="KB909_002271"
     tRNA            618..691
                     /locus_tag="KB909_002271"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="KB909_002272"
     tRNA            711..783
                     /locus_tag="KB909_002272"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="KB909_002273"
     tRNA            811..884
                     /locus_tag="KB909_002273"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="KB909_002274"
     tRNA            898..971
                     /locus_tag="KB909_002274"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="KB909_002275"
     tRNA            995..1084
                     /locus_tag="KB909_002275"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="KB909_002276"
     tRNA            1097..1170
                     /locus_tag="KB909_002276"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="KB909_002277"
     tRNA            1189..1264
                     /locus_tag="KB909_002277"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="KB909_002278"
     tRNA            1266..1336
                     /locus_tag="KB909_002278"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="KB909_002279"
     tRNA            1350..1423
                     /locus_tag="KB909_002279"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="KB909_002280"
     tRNA            1448..1535
                     /locus_tag="KB909_002280"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="KB909_002281"
     tRNA            1557..1628
                     /locus_tag="KB909_002281"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="KB909_002282"
     tRNA            1651..1740
                     /locus_tag="KB909_002282"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="KB909_002283"
     tRNA            1753..1826
                     /locus_tag="KB909_002283"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="KB909_002284"
     tRNA            1845..1917
                     /locus_tag="KB909_002284"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="KB909_002285"
     tRNA            1921..1993
                     /locus_tag="KB909_002285"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="KB909_002286"
     tRNA            1998..2068
                     /locus_tag="KB909_002286"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="KB909_002287"
     tRNA            2081..2154
                     /locus_tag="KB909_002287"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="KB909_002288"
     tRNA            2166..2237
                     /locus_tag="KB909_002288"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="KB909_002289"
     CDS             2503..3696
                     /locus_tag="KB909_002289"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBB6838260.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="KB909_002290"
     CDS             3826..5298
                     /locus_tag="KB909_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838261.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="KB909_002291"
     CDS             5381..6169
                     /locus_tag="KB909_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBB6838262.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="KB909_002292"
     CDS             complement(6236..6904)
                     /locus_tag="KB909_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBB6838263.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="KB909_002293"
     CDS             7019..8731
                     /locus_tag="KB909_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838264.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="KB909_002294"
     CDS             8734..10506
                     /locus_tag="KB909_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838265.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(10588..>10819)
                     /locus_tag="KB909_002295"
     CDS             complement(10588..>10819)
                     /locus_tag="KB909_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838266.1"
                     /translation="NQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMDRV
                     GHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         3103 a         1956 c         2495 g         3265 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag
    10621 ttgattttgc atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc
    10681 atgtcctaca cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat
    10741 gtgggaatgc cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac
    10801 tgctcttaaa gattgatta
//
LOCUS       DADVXK010000095        10576 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.096, whole genome shotgun sequence.
ACCESSION   DADVXK010000095 DADVXK010000000
VERSION     DADVXK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.096"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            33..656
                     /locus_tag="KB909_002296"
     CDS             33..656
                     /locus_tag="KB909_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838267.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="KB909_002297"
     CDS             1106..2155
                     /locus_tag="KB909_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6838268.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="KB909_002298"
     CDS             2152..3033
                     /locus_tag="KB909_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838269.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="KB909_002299"
     CDS             3036..3806
                     /locus_tag="KB909_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838270.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="KB909_002300"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="KB909_002300"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBB6838271.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="KB909_002301"
     CDS             5117..6280
                     /locus_tag="KB909_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6838272.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="KB909_002302"
     CDS             6397..6807
                     /locus_tag="KB909_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6838273.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="KB909_002303"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="KB909_002303"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6838274.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="KB909_002304"
     CDS             9380..9664
                     /locus_tag="KB909_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838275.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="KB909_002305"
     CDS             9824..10060
                     /locus_tag="KB909_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6838276.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="KB909_002306"
     CDS             10057..10455
                     /locus_tag="KB909_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6838277.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3691 a         1770 c         2234 g         2881 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattt
//
LOCUS       DADVXK010000096        10352 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.097, whole genome shotgun sequence.
ACCESSION   DADVXK010000096 DADVXK010000000
VERSION     DADVXK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.097"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            11..310
                     /locus_tag="KB909_002307"
     CDS             11..310
                     /locus_tag="KB909_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6838278.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            383..1744
                     /locus_tag="KB909_002308"
     CDS             383..1744
                     /locus_tag="KB909_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBB6838279.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1766..2026
                     /locus_tag="KB909_002309"
     CDS             1766..2026
                     /locus_tag="KB909_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838280.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2040..2792
                     /locus_tag="KB909_002310"
     CDS             2040..2792
                     /locus_tag="KB909_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBB6838281.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2886..3491)
                     /locus_tag="KB909_002311"
     CDS             complement(2886..3491)
                     /locus_tag="KB909_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6838282.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3544..4518)
                     /locus_tag="KB909_002312"
     CDS             complement(3544..4518)
                     /locus_tag="KB909_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBB6838283.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4896..5615)
                     /locus_tag="KB909_002313"
     CDS             complement(4896..5615)
                     /locus_tag="KB909_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6838284.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5742..7013)
                     /gene="celB"
                     /locus_tag="KB909_002314"
     CDS             complement(5742..7013)
                     /gene="celB"
                     /locus_tag="KB909_002314"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6838285.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7166..8563
                     /locus_tag="KB909_002315"
     CDS             7166..8563
                     /locus_tag="KB909_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6838286.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8644..9084
                     /locus_tag="KB909_002316"
     CDS             8644..9084
                     /locus_tag="KB909_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6838287.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9232..9558
                     /locus_tag="KB909_002317"
     CDS             9232..9558
                     /locus_tag="KB909_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6838288.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9559..10308
                     /locus_tag="KB909_002318"
     CDS             9559..10308
                     /locus_tag="KB909_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838289.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
BASE COUNT         3282 a         1825 c         2148 g         3097 t
ORIGIN      
        1 ggaagaaaaa atgaaaaatc ggttaattgt cgcatgtgga agtggagtag caacgagtca
       61 gacaatcgct agtaagatcc aaagtatgtt agaagatgac ggcatcgcat ttcctgtaga
      121 agcagttgat tacaaatcga ttcaaaatga gcttctaact gctggaatct atgtgtatgt
      181 cgcacaacct gatgaggaag tacttgaaca agcaaaagat ttgggtattg aagtatttcc
      241 aggaattcca tttttaactg gaatgggtgt agaacctatt tatgacagta tcaaagagtt
      301 agtacagtaa aggaggattg ttggataaaa aagttggttc atagttttat ttactatatt
      361 tagaaagaaa gaaggtttat ttatggaagt tttccaaacc attatcaatt atgttttgaa
      421 cttaggatca gccatttttg ttcccctgat tattttgata cttggattgt tggcagggat
      481 gaaattaaaa aaagcattca tgtctgcttt gactttaggg attgctttta gcggaatgtc
      541 tatggtcatt ggctatatgt ctaacgcagt aagtccagca tcagaagcat tggctaaaaa
      601 tacgggaatc agtttgcctg cacttgatct tgggtggaca ggtgcagcaa gcatcacatg
      661 gtcgtggagt tatgctttta tattttttgc agtaacgatt ggggtcaatt ttgtactgtt
      721 actttttaat tggacgaaga cgttaaatgt tgatatgtgg aatgtttggg ggaaagcttt
      781 aactgcttat ttagtttatt atgtttccgg tagtttggct gcaggctttc ttactgcaat
      841 ggtccaagtt atattggaat taaagcttgg tgatatgttt caaaaacata tacaagatct
      901 cacagggatt ccattagtaa cagtgactca ttttatgaca tctgccgctg tcttgttgct
      961 gcctttcaat atgatcatgg ataaaattcc tgctttaaat aaacgagcgg atacgaatgc
     1021 attgaagaag aaaattggga tcttctctga aaactctgta atgggattca ttattggatt
     1081 ggggcttggc tttgctgctg cgtatggcgt ttcaggttct cttaatctag cgatccaaac
     1141 agctacagca ttaagtttgt ttcctatgat ctctaaaatg ttcatgcaat ctttgtctcc
     1201 tctagcagac gctatgtcag aatttatgaa aaagcggttt aaggatcgtg aagtatatat
     1261 cggattggac tggccgatat tagctggtcg ttcagaaatt tgggttactg ctattttact
     1321 tgttcctgtg tttattggtt atgccattat tttgccagga aaccaagtat tgccattagc
     1381 agggattatc aactattcga ttgcggtcgg cggattactt ttaacaggag gaaacttggc
     1441 tcgtatgctg atcttgggaa tcatcactat gcctatttat ttgtacgggg ccacttacct
     1501 tgcgccaata ctcagtgatt tagcagaaaa aagcggagca gtcgagggaa tcaagaaagg
     1561 acagttgatc acatggtcat ccatagaagg gccggagttc agggttttat ttgcggaggc
     1621 atttaatagg aatattctcg ctattgtagg atgcgtgatt tttctaggac tgtttgttct
     1681 actttataaa tatatgataa aagcgaaagt accgagtgaa cgttatgctg aactacaaaa
     1741 atagcattga aatggtggga aagtaatgaa aagagaagag acagataaaa taaaatggac
     1801 agtcgctctt tgtggtacac ttctgctatt tctatatgga ctctttactc agaatatcat
     1861 catcaatcta ttggtcattt ttttcgcact agtgatctat aaatatggaa atcacgtttt
     1921 attcagagag tacgatgaaa aaagaaaacg gaaaatagaa gaatcaatga aaataaaaga
     1981 agctaccaaa gaaatattga gagaaaaaag ttttataaaa agataatgga ggggtcatta
     2041 tgtcagatgg acgtatgtta tttgagagag aacgacagga catggcacgt atcgtaagag
     2101 tgattttcga aaggaaaaac acaaatgtcg caggagggaa tttttccttt aaaaccactg
     2161 atgatcaagg gaaagactac atcatcatga cgccgaccat gatgtcagaa gcctatctag
     2221 gagagatttc tcctgcacag gttctagtag tagaaccaag aacgcgtaga atcgttgacg
     2281 gagtcggtca tttaactcgt gaaatcaata tgcatgaagc gatgtatgag actaatccag
     2341 ctatcaaagc tgtcctacat gctcatgcgc ctaatgcaat gttctgggcg actactgggt
     2401 tgcctatgcc taatttgaca gaagccacag ctaaagtaaa agagattcct gtcatggact
     2461 ttgagcctaa ttgctctgaa gaacttgctg aattgacaag cgactatgta aaaaaacagc
     2521 atctcgaatt accgcatatg ttgctgctca actctcatgg cgtattgatc aacacaggtg
     2581 gagaatcagg aatcgaagct atccataaag cactgcaaat ccttgataca gttgaatgga
     2641 atgcagaaat tgcctacaag cagacgattt ttcaagcatt agggattact gacggttttt
     2701 attcaaaagg tgagaaaatc gggggattgg aagagttgaa acataaaacg gctatttata
     2761 ataaatctgt tattgcagct ggtggagact aacctatctg acacaaaaaa ctacgacttt
     2821 cacaaaatct gatccagatc gatatctgct tcaggttgta ttatgtaagt cgtagttctt
     2881 ttcttttatt tagttaagag gtggtctgtc cattccctcg cttgcttgat ttcgtccatc
     2941 gtcaactgat gacctgttac agttagctga atagtcacat ttgcttggcg tgtttcgaat
     3001 tgatcggcca attctttaaa ggaagcaggg gaaacgattg gatcgttatc accataagaa
     3061 atccagacgg ttttatcctc taatgtggaa cggctttgat gaacacctag agacatcgga
     3121 tggaaaaaca accctttatt tagctcggtc tcacgctcca ataataaatg agcagcgatg
     3181 tttgcgccat ttgaatagcc gacaagcagc cagtcactta acggtatcag ttctttttcg
     3241 ctgatttctt tgattttttc atggagttta tctgtttctt tttccaaact gtccaggtcg
     3301 aattgattca atccattacg cttgaaaaaa cgattcatcc catcttcttg gaccgtgcca
     3361 cgaaaagaaa gcaatgtact gtttggtgca agaaagtgag cgatatccag taaagaatgt
     3421 tcatcgccac ctgtgccatg aagtaagatc aaatgcttgc cacttgttcc tttttcaaaa
     3481 atgtaggtca ttttgttccc tcttttctgt ttctatagat gcaaatgaag tagcatgaag
     3541 agattattca cgttttttat ttgcatcact tgtatcgaaa ggacggacat aagcttcaat
     3601 ggcttcacga cgttcttcta agaatggagg aagagatagt ttttctcctg ctgattctgc
     3661 tggttcatct tcaaggaatc caggaccatc agttgctaat tcaaacagta cgtgatgagc
     3721 ggctaggaag tactcagatt ggaaatagaa acgatcgacg aaaccagaat ttggcaattc
     3781 aatcttattg attacttgaa tccagtattc caatgcttct ttgtctgcta cacgcaatgc
     3841 taagtgatgg atatttccaa atccttcgat tgcttttggc aagtctgtcc gatgttcaat
     3901 aatgatgctt gcaccatttc ccccttcacc gatttcaaat aagtagaaat ctcctgaatg
     3961 gtctgtttct ttgaatccta agattttttc aagaatcaag cggatatgct ctaattgact
     4021 gacacggaca aagacaggtc caagtcctgt gatcgcaaac tctgtcggta cattgctgtt
     4081 tttccaagga atgccagctg ctacaccttg attgttttcg tcagagatca attgataata
     4141 ctgattatcg aaatcttcaa attcgatata ttttttgccg aaacgttcat tgattgctga
     4201 atgagtaacg tcatattttt caaaacgttc caaccaaaag tctaatgctg cgtcacttgg
     4261 cacacggaaa gaagcacgag agatcgtatc tgttcctttt tttccttttg gctgatttgg
     4321 aaaatcaaag aaagtcatat ctgttcctgg cgcaccagta tcgtctgtaa agtaaagatg
     4381 gtaagtttcg atgtcatctt ggttaactgt ttttttgatt aagcgcattc ctaaaatatc
     4441 tgtaaaaaag cggtagattt ttgtagcgct agatgtcatt gctgtgacgt ggtgaattcc
     4501 tctgatttgt gtatccatga taaatttcct cctgttaact tacaaaaagt aagtagttga
     4561 tttagacata gtatagaggg tgcatctcta ttttgcaatt aatttgtctt ctaaagtatc
     4621 aggaaggaat caagaatgga aaagaggagg gacggatcaa taaaataaaa agacttacga
     4681 ctagctgtat cgatttcaaa aaaactagct ttaaaaagct aactttagaa tcattacggg
     4741 tggtcataag tctttttatg ctgagttatt ttttcatttt tgagctaatg cttaggatag
     4801 aatagaatgt tgatttcacg atctcttctt gttacttgaa actgcttacc actgtcacga
     4861 tctcttggta aacggctttt tcacaacctc tttggttaag ttgaacgcac atccagcaca
     4921 gaatagttcc gaacatcaaa tcggtttcgg ctggaagaat attcaatcgg ctgtccatct
     4981 ttgagataga cgacttgctg aacttccagt acaggatcgt tttctgcaca gttcaaatat
     5041 tgctgatcat attcatcact tttatctgca gaaatagcac gataagcccc tgcaaaatgg
     5101 acattcaatt cttgatgaag atgatcatag atagaggcta acaaatgttc tttttttaaa
     5161 cccggcacaa gatggactgg cataaaggta tgctctaaaa catatggctc gccatctaag
     5221 atccttaacc ggtgaatatt gtagacaggt tgctcggcat cgatcatcaa tcgttcttgg
     5281 atatattgat tagggaattc aacatcaaaa tgaatgattt gactcttcaa agaacgatgt
     5341 ctgcgtttca tttggagact caaaccttca tactcgttag cgggcgatgt gtctttttgc
     5401 ataaatggat gattcaagat tttcgttcct gatcctcgct gcgaatagac aagtccttcc
     5461 attgctaaga tattgatggc ttttttgatt gtcatccggc tcgcaccaaa ttcttttacc
     5521 aagtcgactt gattaggcaa aaaactatcg agaggatact cttttgaacg gatacgttct
     5581 cttaaaatat ttgcgatttc ttcgtatttt ggcacgttat tcacctcttc tagagtataa
     5641 cgaaagatta tgcttccgac aactcgaagt agcatctgga acattgttta ttcgaaaaaa
     5701 gaggtcatga caagtttttg tcacaacccc ttaatgatct attaagcaat atctaaatct
     5761 ggttgtttat ctagtacttt caggaatggg taccagataa aggcaacgat gacaaagtcg
     5821 atgacttgca gcataccacc aagccatgaa tttgttgcta agacaccgct tgcaatgatt
     5881 ggcacagtcc atggaacaga gacgccagtt ggtgcaggga caagtccagc agccattacc
     5941 aaataattga acgtcgttac gattagaggt gccacaaccc aaggaataag gattgttgca
     6001 ttcaatacga tcggtagacc gaagatcgct ggttcattta cattgaaaat accaggtgct
     6061 aaagctaatc gtccaacatc acgatactgt ttctttttaa gaacaaaggc catcaataaa
     6121 acgacagcta aagtcattcc agagccacca ataccaacag tgaaggtttc catgaatggt
     6181 tttgtgatga tgtgtggtaa ttcttttcca tgttgataag cttctaagtt atcaagcatc
     6241 agtgtattcc aaatcgggtc cattacagag ttgacgatga tttgtccgtg aagtccgaag
     6301 aaccataaga attggacaaa gaacaaagca atcaatgttg caggtaaact acttcccaaa
     6361 ccagttaatg gtttttggat cacttcataa acgacgtcat gtaagttagc attgaaaata
     6421 ccagtcatca cagcattgat tactaagaaa atagttagtg tcactacagc agggatcaaa
     6481 gcggcaaatg attttgttac tgcaggcgga actccatcag gcattttgat ctgccagccg
     6541 cgtttcgtga ttctgcagta gatttctcca gccaagaaag cagcgatcat tccaatgaac
     6601 attccttttg cgccaagacg atcaagtgaa agcacaccag tcacatcttc accgccagcg
     6661 gttttcattg caaaaggcgt aagaatcaag aagctggcaa aagacacggc accaccgaaa
     6721 ataccttcaa cgtcataaga ttttgataaa taatagccga taccaaaagt aacaaaaacc
     6781 gacatgatgc tcattgttgc attttgccca ttaccgaata aattcgataa agttcccttt
     6841 gttgcgtcac tgaaaaaagg caagttattg ataacgacaa cgatcgaacc gaacatcgtt
     6901 aaagggaagg aaagcatgaa agcatcccgc agcactgtaa ggtaacgatt ttgccctaat
     6961 aaattagcta agggcatgat tttctcagaa agcttgtcca taaaaccgtt catttttatt
     7021 cacctcaaat ttatttgcaa tcgattacat acaaagtata acgccaaaaa ttttaaatgt
     7081 ctagtcattt tcataaaaag tattgattta ttttttaggg ttcgttatga ttacggtatc
     7141 aagaaaaaag agaggaagta aaaaaatgaa aacctacaca ttcccagaaa atttttggtg
     7201 gggttctgct gctagcggac cgcaaacaga aggaagagta agtgatgatg gtaaaggaga
     7261 aaatatttgg gatcattggt atgaattaga gcctgaaaaa ttcttcgatc aagtaggacc
     7321 tgaaaaaact tcgcaagttt acacaaaata caaagaagat gttcagttaa tgaaagaaac
     7381 tggccataac acatttcgta catctatcca atggagtcat ttgattccag aagggacagg
     7441 tgaaatcaat caaaaagctg tttcttttta tcgagattat tttactgaat tgctggataa
     7501 tggtattgaa ccttttgtga acctttacca tttcgatatg ccactaccac tgcaagaaaa
     7561 aggcggatgg ttatcaagag aaacggtcga cgcttatgtt tcttatgcag cagcgtgctt
     7621 tgaactgttt ggagatctgg tcaaaaaatg gtttactcat aatgaaccaa tcgtacctgt
     7681 agaaggaggc tacttgtatc aattccacta tccaaatcat atcaatatga aagaagcggt
     7741 ccaagtaggc tatcatgaga atctagcaag cgcaaaggta atcaaagcct accatgaagg
     7801 cggacatgat ggtgagatcg gaatcatctt gaatctgaca ccaagctatc cgagagatga
     7861 aacgaaccca gaagatgtaa aagcggcgaa gatcgctgac gcattcttca accgatcatt
     7921 ccttgaccct gcagtgaaag gagagtttcc acaagagttg atcgaaattg tcaaagaatt
     7981 ggctataatg ccagagatcc atgaaggaga cctagaactc atccgtgaaa acacgattga
     8041 cctgctagga atcaattact atcagcctcg tcgaatcaaa gcaaaagaaa ctccaatcaa
     8101 tcacgaacat agccccatgc cagatgatta ttttgataat tacgacatgc ccaataaaaa
     8161 aatgaatcca tatcgtggat gggaaattta cgaaaaagga atctatgata ttttaacgaa
     8221 tacaagagaa aactatggta atatcaaatg ctatatttct gaaaatggga tgggggtcga
     8281 aggagaagaa cgatttgtta acagcgaagg aattattgaa gatgattacc ggatcgagtt
     8341 tgttacggat catttgaaat acgtccatca agcaatccaa gaaggaacca attgtgtggg
     8401 ttaccacatg tggacatgta tggacaactg gtcttggaca aatgcttata agaatcgcta
     8461 tggctttatc gctgttgatt tggcacaaga cggtaaacgg acgatcaaaa aatcaggtcg
     8521 ctggtttaaa acggtctctg aaaaaaacgg atttgatgcc tgatattttt tgataaaacg
     8581 ttcacaaaat gtttgttcta acactgtaat cgtgctacac taacagtgaa ggaggcgttt
     8641 acaatggtag atacttatcg taatatttta gtagcaattg atggttctga aaaggcagaa
     8701 aaagcatttc ttgaggcaat cacgattgcc aaacgaaatc aggcaacgtt gcacatcctg
     8761 tatgtcaatg aagtaacagg caattacttt ggtgattttg catttgttac aacaagcctt
     8821 caggaagaat tggatgaggt tgcggaaaac cagatgaaag aacatcgaaa cttggcaatt
     8881 gaaaaaggcc tgacagatat cgagacatat gttctttacg gttatccaaa gacactgatt
     8941 gctaatttcc atgaatcgaa agaaccaatc gatctgattg tcatgggggc gacaggtctg
     9001 aatgcggtag aacgtgcact agtaggttcc actacttcct atgtagtcaa ccacgcatca
     9061 tgtaacgtca tggttgtaaa ataaataaat taagggaaca gaaagcaaaa aagcataacg
     9121 cttcttttgc tttctgttcc ttttattttt ttgtaaaaaa ttactttacc tgatgaagta
     9181 atcatgctat tctaattaca acgacagatg gagtaatatg gaggaaagaa aatgatttca
     9241 agtgatggaa tacgcggata caatgatgcg attattttat cgatccttaa caaaaacgat
     9301 tcttatggat atgaaatttc taaaacgatt cgtgagagga caaatgattc ctatgtgatc
     9361 aaagagacaa cactttactc cgtttttgcc cgtttagaaa agaatcaact gattgtttcg
     9421 tatcctggag aagtgactca tggaaaaaag cggacatatt ataaaatcac tgaaataggg
     9481 cgtaatcttt tagaagaaaa aaagcaagag tggctgacga cgaaagacgt agtcgatcaa
     9541 tttttggagg gaaattaaat ggatacaatc cgtaattatt tagacagtct ttttatcgga
     9601 gtacctcaaa gtaccgagat agataagctg aaaactgatt tgttggcaaa tatggaagac
     9661 cattatcatg aattgatggg agaaggaaaa aatgaacagg aggccatcgg tacagtaatt
     9721 tcgacatttg gttcaatcga tgaattatta gaagaactag atgtcgaaaa aaaacatcaa
     9781 gctgacgaga cggaaacaaa cacagcttct atttatttaa gcgaagcaga aaactactgg
     9841 aaagaataca gagcggcaag tctccaagtg gcatcaggtg ttctattcat tagcttatct
     9901 tttgcaagtt ttcttttctt ttgttcagca ggatatgtgt tcatgggtat ttcttgtctg
     9961 attttcggta tagcattagc tgtcggtttt tttattgctt ctggtatgaa aatcacacgt
    10021 ttaaatcact ttttgcacca tcggaaaata cctgaaaaag tattagcaga agcaaaagaa
    10081 aaagaagaag agtatcagcg aagttttggc ttctcactga ttgcaggaat tggattatgt
    10141 attttttcac ttttcccact tttggcttct ttaatgtggt atatggatgg tagtatcggt
    10201 gcctctatat tttttgttac ggtaggaacg ggtgtcttct tgatcattta tggcagtcta
    10261 gtccgtcatt cttatcgtca attcactcaa agcgcttatt actggtgaat gtattcagat
    10321 ttgtaaaaat attctattta tccggcgtag aa
//
LOCUS       DADVXK010000097        10084 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.098, whole genome shotgun sequence.
ACCESSION   DADVXK010000097 DADVXK010000000
VERSION     DADVXK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.098"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(109..2229)
                     /locus_tag="KB909_002319"
     CDS             complement(109..2229)
                     /locus_tag="KB909_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6838290.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="KB909_002320"
     CDS             2459..3637
                     /locus_tag="KB909_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBB6838291.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="KB909_002321"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="KB909_002321"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBB6838292.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="KB909_002322"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="KB909_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBB6838293.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="KB909_002323"
     CDS             complement(4990..6243)
                     /locus_tag="KB909_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6838294.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="KB909_002324"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="KB909_002324"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBB6838295.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="KB909_002325"
     CDS             7821..9167
                     /locus_tag="KB909_002325"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBB6838296.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="KB909_002326"
     CDS             complement(9475..9861)
                     /locus_tag="KB909_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6838297.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(9910..>10084)
                     /locus_tag="KB909_002327"
     CDS             complement(9910..>10084)
                     /locus_tag="KB909_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6838298.1"
                     /translation="TVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQ
                     RRFEGTLRYSLGY"
BASE COUNT         3215 a         1839 c         2053 g         2977 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttattata cccgtggtgc
     9901 tagttaattt taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg
     9961 acttaataga acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac
    10021 agaacgtgag ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac
    10081 tgtt
//
LOCUS       DADVXK010000098         9864 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.099, whole genome shotgun sequence.
ACCESSION   DADVXK010000098 DADVXK010000000
VERSION     DADVXK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.099"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(218..1096)
                     /locus_tag="KB909_002328"
     CDS             complement(218..1096)
                     /locus_tag="KB909_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6838299.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(1135..2253)
                     /locus_tag="KB909_002329"
     CDS             complement(1135..2253)
                     /locus_tag="KB909_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6838300.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(2250..4349)
                     /locus_tag="KB909_002330"
     CDS             complement(2250..4349)
                     /locus_tag="KB909_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBB6838301.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(4400..5221)
                     /locus_tag="KB909_002331"
     CDS             complement(4400..5221)
                     /locus_tag="KB909_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6838302.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(5218..6027)
                     /locus_tag="KB909_002332"
     CDS             complement(5218..6027)
                     /locus_tag="KB909_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6838303.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(6048..6542)
                     /locus_tag="KB909_002333"
     CDS             complement(6048..6542)
                     /locus_tag="KB909_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6838304.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6554..7042)
                     /locus_tag="KB909_002334"
     CDS             complement(6554..7042)
                     /locus_tag="KB909_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6838305.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(7119..9815)
                     /locus_tag="KB909_002335"
     CDS             complement(7119..9815)
                     /locus_tag="KB909_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6838306.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT         2971 a         2236 c         1639 g         3018 t
ORIGIN      
        1 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
       61 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
      121 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
      181 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
      241 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
      301 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
      361 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
      421 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
      481 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
      541 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
      601 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
      661 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
      721 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
      781 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
      841 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
      901 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
      961 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     1021 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     1081 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     1141 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     1201 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     1261 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     1321 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     1381 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     1441 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     1501 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     1561 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     1621 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     1681 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     1741 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     1801 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     1861 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     1921 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     1981 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     2041 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     2101 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     2161 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     2221 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     2281 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     2341 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     2401 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     2461 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     2521 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     2581 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     2641 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     2701 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     2761 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     2821 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     2881 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     2941 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     3001 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     3061 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     3121 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
     3181 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
     3241 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
     3301 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
     3361 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
     3421 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
     3481 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
     3541 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
     3601 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
     3661 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
     3721 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
     3781 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
     3841 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
     3901 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
     3961 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
     4021 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
     4081 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
     4141 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
     4201 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
     4261 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
     4321 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
     4381 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
     4441 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
     4501 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
     4561 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
     4621 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
     4681 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
     4741 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
     4801 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
     4861 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
     4921 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
     4981 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
     5041 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
     5101 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
     5161 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
     5221 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
     5281 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
     5341 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
     5401 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
     5461 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
     5521 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
     5581 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
     5641 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
     5701 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
     5761 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
     5821 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
     5881 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
     5941 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
     6001 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
     6061 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
     6121 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
     6181 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
     6241 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
     6301 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
     6361 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
     6421 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
     6481 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
     6541 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
     6601 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
     6661 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
     6721 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
     6781 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
     6841 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
     6901 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
     6961 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
     7021 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
     7081 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
     7141 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
     7201 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
     7261 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
     7321 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
     7381 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
     7441 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
     7501 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
     7561 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
     7621 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
     7681 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
     7741 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
     7801 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
     7861 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
     7921 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
     7981 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
     8041 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
     8101 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
     8161 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
     8221 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
     8281 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
     8341 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
     8401 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
     8461 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
     8521 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
     8581 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
     8641 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
     8701 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
     8761 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
     8821 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
     8881 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
     8941 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
     9001 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
     9061 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
     9121 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
     9181 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
     9241 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
     9301 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
     9361 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
     9421 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
     9481 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
     9541 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
     9601 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
     9661 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
     9721 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
     9781 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
     9841 gaatatttgc ctcagatatc tgac
//
LOCUS       DADVXK010000099         9806 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.100, whole genome shotgun sequence.
ACCESSION   DADVXK010000099 DADVXK010000000
VERSION     DADVXK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.100"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            73..810
                     /locus_tag="KB909_002336"
     CDS             73..810
                     /locus_tag="KB909_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6838307.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            824..1639
                     /locus_tag="KB909_002337"
     CDS             824..1639
                     /locus_tag="KB909_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6838308.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1652..2299
                     /locus_tag="KB909_002338"
     CDS             1652..2299
                     /locus_tag="KB909_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6838309.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2315..2971
                     /locus_tag="KB909_002339"
     CDS             2315..2971
                     /locus_tag="KB909_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6838310.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3133..3954
                     /gene="racE"
                     /locus_tag="KB909_002340"
     CDS             3133..3954
                     /gene="racE"
                     /locus_tag="KB909_002340"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBB6838311.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3957..5312
                     /gene="rph"
                     /locus_tag="KB909_002341"
     CDS             3957..5312
                     /gene="rph"
                     /locus_tag="KB909_002341"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBB6838312.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5313..5831
                     /locus_tag="KB909_002342"
     CDS             5313..5831
                     /locus_tag="KB909_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6838313.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5938..6438
                     /locus_tag="KB909_002343"
     CDS             5938..6438
                     /locus_tag="KB909_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6838314.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6718..7638)
                     /locus_tag="KB909_002344"
     CDS             complement(6718..7638)
                     /locus_tag="KB909_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBB6838315.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7803..8816
                     /locus_tag="KB909_002345"
     CDS             7803..8816
                     /locus_tag="KB909_002345"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBB6838316.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(8926..9681)
                     /gene="fabI"
                     /locus_tag="KB909_002346"
     CDS             complement(8926..9681)
                     /gene="fabI"
                     /locus_tag="KB909_002346"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBB6838317.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         3180 a         1712 c         2093 g         2821 t
ORIGIN      
        1 tatcagatat aatgtatttt attatacatc tttaaaagaa atcttactaa ataataatgg
       61 gagtgtaatt ctatggcaat gattaaattt gatcacgtgg ataaatatta tggcaagttc
      121 cacgcattaa aaaatatcaa tctcgaattc gagaaaggag aagttgtcgt tgtcattggt
      181 ccttctggtt caggaaagag cacgatgctt cgctgtatca atggattaga gacgatctct
      241 tcaggtaagc tgctgattaa tgatactgac ttgcatgata aaaagacaaa actgacagaa
      301 gtccgaaaaa acatcggcat ggttttccaa catttcaatt tgtacccaaa taaaactgtt
      361 ctggaaaaca tcaaattagc accaatcaaa gtgttgaagc aagaccaggc aactgcagtc
      421 aaaaacgcgg agaaattttt gaaaactgtc aatatgttag ataagaaaga ttcttatcct
      481 tccatgttat ccgggggaca acagcaacgg gtggcaatcg ccagaggttt agcgatgaat
      541 cctgagatgc tgctgtttga tgaacctact tctgctttgg atccggaaat gattggtgat
      601 gtattagacg ttatgaaaaa attggctcat gacggtatgt caatgattgt cgtgacacat
      661 gaaatgggct ttgccaaaga agtggcggat cgtgttatct tcatggctga tggagaagta
      721 ttggaagaca gcagaaatgt gagagacttt ttcgaaaatc caaatgaagt ccgagcacag
      781 caatttatca gtaaagttat caatcattga taggaggaaa aagatgcgca ggttaaaaaa
      841 aatacgcctg attttccttt taggcattgc ttttcttgca ctagccggat gtaaaggaaa
      901 tgggttggca aatgaagata ttttagagcg aagcaaatct accaatgaaa tcatctgggg
      961 tgtcaagtat gatactcgat tatttggaat gatggatatt gagagcagaa ctgtacaagg
     1021 atttgatgta gatattgcaa aagcaatcac taaaaagatc cttggtgaca atggaaaaac
     1081 agaatttgtt gaagtcactt ctaaaactcg gattccatta ttgaaaaacg gaaatatcga
     1141 tgcaattatt gcaacgatga cgatcacaga tgaacgaaaa aaacaggttg acttttcaga
     1201 tgtctatttc gatgctggcc aagctttgtt ggtaaagaaa ggaagccaaa tcaaaagtgt
     1261 agatgatttg aatgcttcta caacggttct agcagtcaaa ggttctacat cggctgcgaa
     1321 tatccgacag catgcaccag atgcaaaaat tttagaatta gaaaactatg cagaagcatt
     1381 tactgcttta caatctggtc agggagacgc gatgactacg gataatgcga ttttgttagg
     1441 gattgcagat gaaaatccag agtatgagtt agttggtgga acgtttacta atgagcctta
     1501 cgggattgcg atcaacaaag ggcaagaaaa cttcttgaaa gctgttaacc aagcgctaga
     1561 ggaaatgcat gcagatggca catacgataa aatctatcaa aaatggtttc caaatgaaac
     1621 tgaaggaaaa gtagagtaag ggggagaggc aatgagcgaa ttgatacaaa cttatggacc
     1681 aatctttgtc gacgggttca agatcacatt gttttcgagt gtcttagcac ttgtgtttag
     1741 tttgattatc ggaacgttaa tggcaatctt ccaattatca aagaataaag tagtgagcgc
     1801 cttagcaaag gcatatgtag aattttttag aaacattcca ttattaatca tcgtgatgtt
     1861 tttttatgtt gtcgtaccga tttattggtt taatctagat ggattccaag caggtacgat
     1921 tggattaacg atctatacat ctgcttttat tgctgaaaca gtacgttcag ggattcaaac
     1981 cgtaccaaaa ggtcaaacag aagcaggact atcttctggt tttacctatt cagaaatcat
     2041 gcgttatatt gttttaccgc aagcattcaa aatcgttatc ccgccattag gcaaccaatt
     2101 tatcaacctc gtaaaaaact catctatttt agcaatcgta gctggtttag atttgatgta
     2161 tcaaggagac ttgatcgcta gtgaaacatt caataccttc gatacgtata tcatcgttgg
     2221 gttattttac ttagttatca cgctaccgtt atcttactta atggtttatc ttgagaaaaa
     2281 atgggcggtt cgttcataga aggaggggaa atacatggat tttagcggcg ctttttcatg
     2341 gatgaatatc cgttttttat tggaaggatt aaaggttact gttgaagttt cattgttttc
     2401 gatcattttt agtttcttga tcggtggtct gacaggtgtg attcgttttg cgaatatccc
     2461 tttcttttcc aaaatccttg gtgtagtgat tgatattata cggaatcttc cattattatt
     2521 gatcattttc ttcacttact ttgccttacc tcaaatcggc attcagatga acatcttctg
     2581 gtccgctgtc gcagcattaa cgatttttga gtcagctatg ttgtcggaaa ttttccgagc
     2641 tggactcaat gctgttccaa aaggacagat ggaagcagga ttatcaacgg gactgactta
     2701 tgtagaatcg atgcgaacga tcgtgttacc gcaagcattt aaatcaatga tcccggcaat
     2761 tgtgagccaa ttgatttcac tgatcaaaga tacttcatta gcagtaatca tttctttacc
     2821 tgaactttct catcaggcac gtattattta tggacagaac accaattatg tgcttccgat
     2881 gttcatcatc atgacactta tgtacttcgt ggtatgttac gcgctttctc tgctttccgg
     2941 ttacttggaa aagagacggt acagttatta atagatgatt cttttagcgg ttgtggcaaa
     3001 ctaaagtcac aaccgctttt cctctttcca ttcgaaaaaa agagatttcg attgttttaa
     3061 gcaagtaaga gcacttgaaa attcacgcta aaaagtacac aatagggagg atagaattta
     3121 ttgaaaaaaa ggatgatacg attgacagat aatcgcccta tcggatttat tgattcaggt
     3181 gtcggcggct tgactgtagt aaaagaagcc ctgaaacaat taccgaatga aaatatttta
     3241 tttgtaggag acacagcacg ctgcccatat ggccctagac ccgcggaaca ggtaatccag
     3301 tatacttggg aaatgacgga ttatctggtg gagcaaggaa tcaagatgct ggtgatcgcc
     3361 tgcaataccg caactgcggt ggctttagaa gaaatcaaag ctgctctttc tattccagtc
     3421 atcggtgtga tccttcccgg tactagagcg gcagtaaaaa aaacacaaaa taaacaagtt
     3481 ggcattatcg gtacgattgg tacggtaaaa agtcaagctt atgaaaaagc actgaaagag
     3541 aaagtaccag aattgactgt gacaagtctt gcttgtccca aatttgtttc agttgtcgaa
     3601 agtaatgaat accattcatc ggtggcgaaa aaaattgtgg cagaaacatt agctccttta
     3661 accactaaaa aaatcgatac attgattttg ggatgcaccc attatccatt attacgcccc
     3721 atcattcaaa atgtaatggg agaaaatgtt caactgatcg attctggagc agaaacagta
     3781 ggtgaagtat ctatgctgtt agattatttc aatttgagca attcaccgca aaatggtcgg
     3841 acattatgcc agttttatac aactggctct gccaaacttt tcgaggaaat agctgaagac
     3901 tggcttggaa tcggacactt aaatgtagaa catatcgaat tgggaggaaa ataaggatgc
     3961 gtcatgacgg gagaaaagcc caagagcttc gcaaactgga gcttcaaaca aatgttttca
     4021 aatatccaga aggatcggta gtgatccgtt ttggtgatac aacagttatt tgttctgcaa
     4081 caatagaaaa ttctgttccc ccttttttga gagaaacagg aacaggatgg gtgacagcag
     4141 aatatagtat gctgcctcga gcaacgagta cgagaaatcg tagagaaagc agcaaaggga
     4201 aactttctgg tagaacaatg gaaatccagc gtcttattgg tcgttccttg cgtgcagtag
     4261 tagacttgga aaaattagga gaacgtagta tcatcgtaga ctgcgatgtg atccaagcgg
     4321 atggcggtac tagaacagca agtatcactg gggcatttgt ggcattgaaa ttagccattg
     4381 aaaaactttt aagagaaaaa gaattgtcag aagatccaat aaaagaacat cttgctgcag
     4441 ttagcgtagg aatcttacca gatgggactt gcgtcacaga tttggattac caagaagatt
     4501 ccgcagcact tgtagacatg aatcttgtaa tgacagaatc tggaaaattc gtggagattc
     4561 aaggaactgg agaagaagca acgtttgatg gtgaacagtt gaatgaaatg ctcttttttg
     4621 gaaaaaacgc gattgaagat ttgatcaaag agcaaaaaca tgctttgcta acagagtttg
     4681 ctcaaaatga tgagcggata gaagaaacaa aaacaatcat cattgcgaca agaaatccag
     4741 gaaaagcaga agagtttcga aatatgttca aagaagcggg atatcatgta aaaacattac
     4801 ttgactatcc tgaattgcca gatgtggaag aaactggcag cacatttgaa gaaaatgccc
     4861 gattaaaagc agaaacgatt gcacaattgc ttgatcagcc agtcttagca gatgattcag
     4921 gtttgaaagt ggatgcttta ggcggtatgc caggaatcta ttctgcacgt tttgcagggg
     4981 aacaaaaaag tgatgcgggg aataacgcca aattattata tgaattgaca gatgtgccgg
     5041 atgaaaaaag aacagcacaa ttccattgta cgttagtatt cgcggcaccc aaaaaagaca
     5101 gccttgtagt agaagcggaa tggcccggtc gagtagcccg tataccatct ggcgaaaatg
     5161 gctttgggta tgatccttta tttatcccag aaggtaagaa acaaacagca gcagaattat
     5221 cgagcgaaga aaaaaacaag atcagtcatc gggctcaagc aatgaaaaaa ttgagtgccg
     5281 agtggaaaca atggctggaa ggagagagat agatgcggta tttagtagta agtgataatc
     5341 atggagacag agatatcctc gttgacttag tagatcgtta tcgttctgaa gtggatatct
     5401 ttttccattg tggtgattcg gaattagaag cttctgaccc attatgggat acattccaag
     5461 tggttcaagg taattgtgat tatggaccag gattcgaaca gaaaaaagtg atccaaactg
     5521 gtcaggatac agtattcatg actcacggtc atttatcgaa tgtccgattt ggtttgacac
     5581 agttagcaat cgaagctcga gctgcaactg ccgatatggt gttttttggt catacccatc
     5641 aaataggctg tgagatggat cagaaaatcc tgtttttgaa tcctggtagc atttctcagc
     5701 ctagaggccc gatccaaatc ccatcatatg ctcttatcga aagtttagat gaccaaattt
     5761 ctgttcaata ctataaccgt gcccatcagg cagttgaaga gttggccttt tctttttcga
     5821 gagagcgctg aataaaaaaa ctctaatttt taataaaaat aagctttatt ttatgaattt
     5881 tgcatccggt ttcggtaaaa tagtagtgtt gaatgaaata gaaatggagg ccatcagatg
     5941 attggaccta tagtaagaga aatgctgctg gaaaatcagg aaacgttttt gattcctgca
     6001 gaaaatgtgg caaatgttat gtatcatcat ccattgtccc atggtttact tgtgttatcg
     6061 aaggtcggtt attccaaaat tcctgtatta ggaaaagatg atcactttgt aggactagta
     6121 agtttatcag atgtggtcaa taaaatgatt gacttgcaaa caatcagcat ggacccgtta
     6181 gaaggactaa cggttgctga tgtgacagaa acagatgttc cgacaattga tgaaaattgg
     6241 gaactagaag aagtactcca tttgttagtc gattcgcctt ttttaccggt tgtcacagaa
     6301 gatcggattt tcaaaggaat cattacaaga aaagagctgc ttaaagccgt aaacttcatg
     6361 gtgcatgaat tagaacgtcg taatatattg tctccgaaaa tcgaagaatt aaaagaacaa
     6421 atcgatatcg tgagctaaag aacgagaaac taaaagataa tcaaaaaata agtagaaaaa
     6481 acagcgtacc agttttgact ttatcttgaa aaagaggctg ggacaaaagc gtttaactcc
     6541 aagaaataag aaggaattca cgaaaattgc ttttcaaatt tttgtgaatt tcagcttatt
     6601 tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt tagagcgtgg gacaaaagtg
     6661 ttctttactt ttgtcccacg ctctttttag tgagattcgt tgcatcgttt gtccaaatta
     6721 ttttccgaca gcaattggac tgttcggaat cgtgaaacca gaagctgtca attctttgac
     6781 ataggagctc aagaactctt cttttaaggc atattgtttt ccgttcaatg cgtagcagac
     6841 cgtacgaatc gcaaaattgc tgtttccaag atccactaat ccaaagatag aaggttcagt
     6901 ttggagctct tcttggtatt tttcagctaa tgtacgattt actcgatcaa tgatctcata
     6961 gattttgtca tatccttctt caggaacaat ccgaatatct aaaagtactt gcatatttgc
     7021 acgagagaga ttgctgatcg tggtgatgtt tcgattcggg atgaaatgga cagtaccatc
     7081 cgttgctttc agctgaaggg tacggatacc aacagatacg acggttcctt caatcgttaa
     7141 gtttgctagc ttgatgtagt ccccaacatc catctgttgt tccatgataa taaaaaatcc
     7201 ggtaataaca tcactcatga acccttgggc accaagaccg attgccacac ctgcaattcc
     7261 ggcaccagcc aaaagtgatc cgatcggcac accgatagca gataaaattg catagataaa
     7321 aaagaaacca agggtataat gaaaaatagt atttaaaaga ctatgtaaag tctttaagcg
     7381 gctctcgttt agaatggctt ttttagaata ctgattaaaa gacttatcaa tcagatattt
     7441 tcccacacgg tgaagaatcc aaaaaaggac gatcaaaaaa atcagatata aacttttttg
     7501 gataaaggca gccaaaatgg cgtcccaatc aatcccgtcc caaaaccgct gaaacgcatt
     7561 tactttgctg acagcttgat ctgtcaatgt ctcgccagaa gagtctgtcg taccggcagt
     7621 tgctaataat gaaaacataa aatcctcttt tctaaaattt gattctttct gtattgtacc
     7681 aagaagtttt caaaaaagga aatagcaaaa ataactataa tgaaggaaaa aagctgaaaa
     7741 taaaatgaca aataatatgg ataatgataa aatgtggaga aaataacgaa ggtggtaagt
     7801 atatgcaaat cgattggaac aatctaggtt tttcttatat caaaactcct tggcgtttta
     7861 ttgccaaatg gaaagacgga caatgggaag aaggagaatt gacagaagat aattacctga
     7921 cgattcatga aggctctcca gcgcttcatt atggtcagca atgttttgaa ggtctaaaag
     7981 cttatcgtcg aaaagacggc aaggtcaatc tctttcgacc tgaacaaaat agtcgacgga
     8041 tgaatcaaag tgctagacga ttgctgatgc caatggtccc tgaaaagatg ttcgttgatg
     8101 ctgtcaagca agtggtaaaa gcaaatgaag attttgtgcc gccctatgga acaggcgcta
     8161 cattatactt gcgcccttta ctgattgggg tcggtgaaaa cattggtgtc catccagctc
     8221 cagaatattt atttgtcgtc ttctgtacgc cagtaggagc gtatttcaaa ggtggactaa
     8281 aaccaacgaa ttttattgta tctgattacg atcgtgctgc tcctaagggg actggtgcag
     8341 caaaagtcgg cggaaattac gcagcgagtt tacttccagg aacagaagca aaagaactgg
     8401 attactcaga ttgtgtttat cttgatccag ccacacatac gaaaatcgaa gaagtaggtg
     8461 cagcaaattt ctttggaatt acaaaagacg gaaaattcat cactccgcaa tcgccctcta
     8521 tcttaccaag tatcacgaaa tattccttgt tgcagttagc tgaagaacga ctaggactgc
     8581 aagcaattga aggagatatt ttcattgatg atctagatca atttgcagaa gctggtgcat
     8641 gtggtacagc ggctgttatt tctccaatcg gtgggattta tcacaataac aatcttcatg
     8701 tattttatag tgaaacggaa gtaggaccag taacaaaacg gttgtatgat gaattgacag
     8761 gtattcaatt tggagacata gaagcaccag aaggctggat tgaagtcgtg gaataatttc
     8821 aaagtaatga gttgaaaaaa acgtaaaaag aaaaaatcag gaagagactt taaaaagttt
     8881 tttcctgatt tttatatgtt ttactttaaa gaatgcaaca aaagtttatg aaagatggac
     8941 acctttgtca acgtagataa tatcaccgat gattccgctg gaaagtgggc tgattaagaa
     9001 agcacaagca ttaccgactt cttcgatcgt cacaccttgc tgatcaggcg tacgagattc
     9061 agataactgg atcagttttt gatagtcttt aacacctgtg acagctaatg ttttgattgc
     9121 cccagctgag attccattga cccgaattcc tttaggcgag aactcagctg ccaaataacg
     9181 gatagcagct tcaagagaag ctttcgcaat acccatcatg ttataattcg ggattgcgcg
     9241 ttctgaacct agataagtca tgctaacgat cccgctgttt ggtgcaagaa acggttgtgc
     9301 gtattttgat acagcaatta aagagtagct gctgatatct tgagctaatt gatagccgtc
     9361 tctggaaata tcagacacat ttccggacaa ttcttctttg ttggcgtaag caactgcatg
     9421 gacaaggccg tggatctccc cagcatattc accgatggca ttcattgctt tttcgatgct
     9481 ttcgtcgcta gaaacatcac attctacagt gaatgcttct tcgccgacca atttgactaa
     9541 tgattttttc attcgttcat tttggtaagt atagataatt tctgcccctt gtttcaacat
     9601 tgcttcagca caaccccaag caatgctttt tttgttagcg acgcccataa tgacgatttt
     9661 ttttccttct agaaatgaca taatgactct cctttgtttc tgataaaaat ttgatagtcg
     9721 taaaaaaata gagaataata gctaaaataa cttcttgatt tcttaattat tagtcaaaat
     9781 gttttgattg tcaaactatt ttttct
//
LOCUS       DADVXK010000100         9762 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.101, whole genome shotgun sequence.
ACCESSION   DADVXK010000100 DADVXK010000000
VERSION     DADVXK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.101"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1031)
                     /locus_tag="KB909_002347"
     CDS             complement(<1..1031)
                     /locus_tag="KB909_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838318.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="KB909_002348"
     CDS             complement(1113..1802)
                     /locus_tag="KB909_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6838319.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="KB909_002349"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="KB909_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBB6838320.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="KB909_002350"
     CDS             complement(2329..2832)
                     /locus_tag="KB909_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBB6838321.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="KB909_002351"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="KB909_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBB6838322.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="KB909_002352"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="KB909_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBB6838323.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="KB909_002353"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="KB909_002353"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBB6838324.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="KB909_002354"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="KB909_002354"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBB6838325.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="KB909_002355"
     CDS             complement(6444..7463)
                     /locus_tag="KB909_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6838326.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="KB909_002356"
     CDS             complement(7636..8541)
                     /locus_tag="KB909_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6838327.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="KB909_002357"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="KB909_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBB6838328.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="KB909_002358"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="KB909_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBB6838329.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="KB909_002359"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="KB909_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6838330.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
BASE COUNT         2762 a         2056 c         1789 g         3155 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat ta
//
LOCUS       DADVXK010000101         9470 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.102, whole genome shotgun sequence.
ACCESSION   DADVXK010000101 DADVXK010000000
VERSION     DADVXK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.102"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            232..2067
                     /gene="tdc"
                     /locus_tag="KB909_002360"
     CDS             232..2067
                     /gene="tdc"
                     /locus_tag="KB909_002360"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6838331.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2372..3850
                     /locus_tag="KB909_002361"
     CDS             2372..3850
                     /locus_tag="KB909_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838332.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3816..5147
                     /locus_tag="KB909_002362"
     CDS             3816..5147
                     /locus_tag="KB909_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838333.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5261..7813
                     /locus_tag="KB909_002363"
     CDS             5261..7813
                     /locus_tag="KB909_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBB6838334.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7820..9259)
                     /locus_tag="KB909_002364"
     CDS             complement(7820..9259)
                     /locus_tag="KB909_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838335.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
BASE COUNT         2978 a         1577 c         2019 g         2896 t
ORIGIN      
        1 cgcttttttt aggttatcta ttttagaaga ctgatttatt gaaaaattgt tcgctttttt
       61 gcgttgaatt atcagaaaaa tccgacttta tttatttttg tttgtaaaaa tctacgtgga
      121 tttgatgtta taaaaaaaaa attctcattt ttggcgctat agtgaagagg tgttacagat
      181 aaacacatgt atctgcaaga cattgaccaa caaaatatgg agggaagaaa aatgaaagat
      241 atggatatca aggccgtctt tataggcgac aaagctgaaa atggaccagt ttataaaatg
      301 ttgttgaaca agatggtaga tgaacatctt ggatggagag aaaattatat tccttcagat
      361 atgcctgcaa ttagcgaagg agataagctc actccagatt atctagccac ccgcgaccat
      421 atgatagagg tcttggatga agtcagtcag cgattacgcg caggatcgat cccatggcat
      481 tcagcaggcc gttactgggg acaaatgaat gctgaaacat tgatgcctgc tttattagct
      541 tacaactatg cgatgctgtg gaacccaaat aatgttgcat tggaatcttc tatggcaact
      601 tcgcaaatgg aagcagaagt aggacaggat tttgcttcat tattcaatat gacagacgga
      661 tggggacaca ttgcagcaga tggttctatt gctaatcttg aaggattatg gtacgcccgt
      721 tgcatcaaat cgattccttt agctgtcaag gaagtgctgc ctgaaaaagt gaaaaaaatg
      781 tctgagtggg aacttttgaa tttatctgtt gaagaaattt tggaaatgac cgaaagcttt
      841 acggacgaag aaatggatga ggtcaaagca gcttcttccc gtagcggaaa aaatatccaa
      901 agattaggga aatggctggt ccctcaaaca aaacactatt cttggatgaa ggcgttagat
      961 atttgcggag tcggcttaga tcagatggtt gctatcccag ttcaagagga ttatcgaatg
     1021 gatattaatg ctttggaaaa aacaattcgt gaattagctg gacaaaaaat cccaattcta
     1081 ggtgtggttg ctgtcgtagg aacgacagaa gaaggtcaag tagacagtgt agataaaatc
     1141 gtccaattaa gagaaaggtt aaaagatgaa gggatctatt tctatttaca tgttgatgcc
     1201 gcatatggcg gctatgcgcg ttcactgttt ctaaacgaag caggagaatt tgtgccgtat
     1261 gcttccttag ctgaattctt tgaagaacat catgttttcc accactgcgt aacgattgac
     1321 aaagaggtat atgaagggtt cagagctatt tcagaagcgg attctgtcac gatagatcct
     1381 cataagatgg gctatgtccc ttatgctgct ggaggaatcg taatcaaaca taaaaatatg
     1441 agaaatatca tttcttattt cgcgccatat gtgtttgaaa aatcagtaaa ggctccagat
     1501 atgttaggag cttatatttt ggaaggatca aaagctggag caaccgccgc cgcagtctgg
     1561 acagcacatc gtgtattgcc attgaatgtg accggatatg gtcaattgat tggggcttca
     1621 atcgaggcag ctcaaagatt cagagaattt ctcgatcatc tgacttttac tgttaaagga
     1681 aaaacaatcg aagtctatcc attgaatcat cctgatttta atatggtcaa ttgggtattc
     1741 aaagaacaag gctgtacaga tttgaacgct atcaatgaat taaatgaaaa aatgttcgat
     1801 cggtcttctt atatggatgg cgatgtttat ggtgaacggt ttattacttc tcatactaca
     1861 tttacacaag aagattacgg tgattctccg attcgttttg ttgaaagaat gggtctaacg
     1921 aaagaagaat ggaaaaaaga acagaaaatc actctgctac gtgcggctat catgactcct
     1981 tatttgaatg atgatcgaat tttcaatttt tatacaaaaa aaatcgccaa agcaatggaa
     2041 aagaaactaa acgaaatcat ccaatagaac tgatttttgt gtgaaagaat aacaagagac
     2101 atatggagaa cagacaatta tttgcttcat caaaacaatt gtatttcccc ctgtttttca
     2161 tatattcctc gccaagatat tcttttttat aaaacgttct ataagttgga tcgttcgttt
     2221 catgtatcaa acccagttca ctaagatcgt tcaatggatg tttcggtgat actgggtttt
     2281 gtactgaatc gatgaaacct tgtcatttct gttcttgaac aaaaataaaa gaaaacaaaa
     2341 acatatgtcg ctattgaaag aaggaataaa gatgaaagat actggttcat caaagcaaat
     2401 cacgaccatg acctttatcg gaatgacctg cgcccttgta gcaagtgtac gaaatattcc
     2461 agatgtagca gcaacgagct ggacgatgat tttttacatg ctggttgcag tattattgta
     2521 cgcttttcca atctcattga tctctggtga atttgctgga atgtttcccc aaaaaggtgg
     2581 tccagaactt tgggtatcga atgctctagg aaaaaaatgg gggttcgttg tctcatggct
     2641 gttatgggtc caaatgtttc ctgggatggt gatggtcgct tcagcactcg ctccgttgtt
     2701 tggtaatatt atcgataatg tgccgcttgg tttgaacagc aaatttacat tagttgtcat
     2761 tttagtcgtt tattggatca tcactttttt gaatttgaaa tttgatatgg caaaaatcgg
     2821 cggaaaagtc ggtgtttggt taggattgta cgtgcctttg acgatgatgc tcttattagg
     2881 gtttgctgcg tggatcaaag ttgggatcgt accaaccgga acattaggca gtttttcatg
     2941 ggacaaatta ataccagata ctacgactgc atcctcattt gtttattttg cgccgatcat
     3001 gtttattttt actggtatcg aaatgtcctc tgtgtatatc actcgattgg aaaatccagt
     3061 taaaacgtat attcgcggag tatttgccgc gttaattttt atatttttcg tcaatatttt
     3121 gaatgcttta gttgtagcaa atgtcgtacc aaaaggacaa atggaattga ataatatcgc
     3181 gcaatctatt tcgatttatt gccaaattct tggtttgcca catcttattg tgaatctgtt
     3241 tagtttactt gtcttcattg gtgtagcagt ccaattatct gcttgggcct caggaccagc
     3301 aaagacagtg acagaaagtg ctagaaaagg tgcgtatcca ccaaaattca atttttggaa
     3361 gacgaatcaa tttgacgtat ccaaatccgt tattttgact cagtctgtca ttatctcaat
     3421 ctttgcactt ttttatttgc tgattcctgg cgtcaatcaa gcatttttga tgctcgtaaa
     3481 ttcaactact gttatctact gtatcgtcta tgtcatcatg gggatcgcag ttttgagatt
     3541 gcgttataca catgcaaagt tgaatcgacc atttagaatt ggaaaaaaag agaaaaagag
     3601 caatcttgga gtttggactg tcgttattgt tttatttgcg gcaatcggat tttctgtcgg
     3661 actgacgatg aaagctggaa catggatcaa tctaattgca gtcacagcca tcagtgtcat
     3721 tttgtttgta gtaccactct gtattgaaaa aataaagaaa ccttcttggg aacaggaagt
     3781 cgccatgctg cttgaaaaag aaaaaggtga acttgatgga aaaaccggca atgaaacgga
     3841 ctctaactaa tcgaaatatc cagttaatcg cattaggtgg cgcaattgga acaggattat
     3901 ttttaggttc agcaaaggca attgcatcag cagggccagc tgttattctc gtttatttga
     3961 tatgcggttt ggctatttat ggtttgatgc gggccatggg tgatttattt ttagcaaata
     4021 gtacatttaa ctctatcagt gatttcgttg actattattt aggcaaaaag tgggcatttt
     4081 ttgtcaattg gacttattgg ctttgctggc ttggagctgg acttgcggaa ttaacagcaa
     4141 taggattgta tatccatttc tggtttgtac atgtaccagc tttgataagc ggaggtagcg
     4201 cactaatgat cttaatggca gtcaaccttg ttgcagtcaa gtggtttggt gaattggaat
     4261 cttttttctc aatcatcaag atcttgggga ttttcctttt tatcttattg ggtataggat
     4321 tgagtgtctc agattttcat acccagtcta tcggaatcaa agaaaatttt ggacagatcg
     4381 atgaattact accgtttggc tttgctggaa tggtagtctc atttcctatg gttttattca
     4441 gttttgctgg aattgaaatg atcggcttaa ccgttggcga gacaagtgat ccgcaaaaga
     4501 atttgaaaaa agcaatcaac tgtctgcctt ggcgtattct ctttttctat ataggaacga
     4561 ttttgtcgat tttatttgtt gttccatggc attgtttaga tttaaaagaa agtcctttag
     4621 tgactatgct gcaagtgatc cattgccaag gcggagcagc aattgtcaat ctaatgattt
     4681 tggttgcttc tttgtcctca gcaaatagtg cagtctacag tactagcagg attttatatc
     4741 aaacagcaaa agaaaaaagt ttgccccatt ggttttgtgc gctttctaag aaaggcgtac
     4801 ctttacacgg tattttaatt acaggaatgt tattttttgc cggtctttgt ctacattttt
     4861 ttgtagctga tagtcgattg ttttttcagc ttttggcagg catgacaacg agttgttttc
     4921 tatttgtgtg gtcttcgatc ttgtgtgcac atgttcaatt tattaaagaa aagaaacgga
     4981 acactacaca aagatataaa gatcttgctt tgttggtgtt ttttacttca attgctttca
     5041 gcttgttatt cgaaagcacg acacgcttta ttcctttttt attggttatc tggtttgtat
     5101 tcttaaattt tgtatataaa agaataagca atagaaatat cagttaggcc cagatacatt
     5161 ttgcaaaacg aattatttca gacccccctg aaataatcga tacgcctgaa aaaacttccc
     5221 tgcgtataat aacagtatca attaaacagg aggggatagg atgaactggt acagattgac
     5281 ggtagaagat gtattgaaaa actatcaaac atcaacagaa ggcttgtcgc aagaagaacg
     5341 acagaaacgc ctgactgatc aaggatataa tgaaataaaa gcaaggcagc agacaaaacg
     5401 atggaaaaaa atagcaaagc attttactga tctgctgatg atcgtgttga tcattgcctc
     5461 ttttttgaaa tttgcttcta gtgaatatat tgaaggaagt attattttat tcgtagtgat
     5521 cgtcaatgga ctcgttagtt actggcaaga aagaaaagcg gaagaatcat tgaatggttt
     5581 gaagcagctg atgggacaag aagcgatagt actatcaaac gggatgcaag aaaaaatccc
     5641 tgcgaaagaa ctggtaaaag gagatgtcat tgtcttacgt gccggagatg tcgttccagc
     5701 agatatccga ttaatcgaag cacatgattt attagtggaa gaatcgattt tgacgggaga
     5761 atcagaagca tctgaaaaaa gtcatgccgt tttgacagaa gaagaatcga tcggcgacca
     5821 gaaaaatatg ggtttttcag gaacgcttgt acaatctggt tctgcagtcg gtgtcgttgt
     5881 agaaacagga aacacgacag aaatcggtaa aatcaatcaa gcattgcaat cggtcgaaca
     5941 acaaacgacg cctctgatta aaaaaatcaa ccgattaaac aaacaaattt ttcaaggcat
     6001 tctttgtttg agcctattct tagttatttt tacgacattt cgatatggta tggattggca
     6061 tatccttctt tcggctacga ttgctttggt ggtgtcaatg gtacccgaag gattgccagc
     6121 tgttttgacc atgattctat ccgttggagt acatgaaatg gcaaaagaaa aggcgatcat
     6181 caaaggactt ccttcggtag aaacattagg ttctatgaca gtgatctgtt cagataagac
     6241 aggaacattg acaaaaaatg aaatgacagt tgtggatgta gctgcaaaag aagaagcctg
     6301 cgtgttgtcc attatgaaaa actgtcagga attaaaaaca aaagaagaac agaaaacaga
     6361 aaatttaagt ggcaatccga cagaagttgc gctgattcga cacacagaaa cagccaatct
     6421 acctttgaaa aaaatagaag caaagattcc gttcagttct gaatacaaat atatggcaac
     6481 gatgcatgcg gaggaaaaag gagcggtgat ttacgtcaaa ggtgcaccag aagtattatt
     6541 tgctaaatca actctttctt ctgcagaaca agaagcatgg agtcagacag ctgcagaatt
     6601 tgcgagaaaa ggtcagcgtg ttttaggatt tgcttataaa aaagtagatt cgaaacagga
     6661 actcacgcat gagactttaa cccaattaac ttttgcaggg atcgccggat tgatcgatcc
     6721 gccaaaagaa agtgcagtca aagctgtaaa ggaatgccaa caagcaggga tctcagtgaa
     6781 aatgattaca ggggatcaca aagacacagc aaaagcgatt gcggaacaaa ttggcttaaa
     6841 acatactgcc aaagttttag aagggatcga tttggatctt atgtctgatg aagagttgat
     6901 tcagcaagtg ccaatagtcg atgtctttgc tcgaacgaca ccagaacata aactgcgaat
     6961 tgttaaagct ttgcagaaaa atggagaaat cgtcggaatg accggagacg gcgtaaatga
     7021 tgcacctgct ttgaaaagat ccgatgtagg aattgctatg ggaatcaaag gtagtgaagt
     7081 aagcaaacag gcagctgata tggttttagg agatgataat ttccatacga ttgcaaaagc
     7141 cgtaaaagag ggccggcgga ttttggataa tttgcaaaaa accatcaatt tcttcttgcc
     7201 aactgcatta gctcaaggat tgatcttgat ttgggcactt atgctgaatc gcccgctacc
     7261 tttgtcccca gtacagattt tatgggtcaa tatggtaacg acaatcactt tatcttatgc
     7321 actagggttc gagtcgccag atccagaaat catgaagcgc ccaccaagag atccaaagca
     7381 aggaatccta tctggttatc atttgtttcg gatcatctat gtctccctac tgatcatggt
     7441 tcctgcctat ttattggcta tgcagtttga agggcaaagc ttacagcaaa ccattcttct
     7501 gcaaaatatc gtcttagctc aagctgttta catgatcaat tgcagagagt tgtccaagcc
     7561 gtcattgaac caaggtcttt tgcaaaacaa agcgcttttt ctttcattag gtatccttgc
     7621 tttattgcaa gggatggtta tttttctacc agtcggccag cagctgatcg gtacagtaag
     7681 tttaacgatg acacaacagt tattgattgg agcaaatgtg attcttctat tcttagttgt
     7741 agaaatagaa aaagggatca tgaacaaact gtttcgcaaa aaagaaaaaa cagctagaga
     7801 atacagtcgc tagccgttac tataaaaaag ttttgaaagt gagttcagtc aaacgattga
     7861 gctcattttt cgttggaata gaagaaatgt atacaatagg gatatctaga gaatctagag
     7921 ggaaattgga aatcaagata tctgtttttt caaaagaaat agtggaaaga tcggttagtt
     7981 cgataggtaa gaagcagaca cgttttccta agtaatcttt taattcctgc tgcaagaacg
     8041 ccttccatga aggttctcct tggaaaataa aatagacatt gaacaaattc ggtttgatag
     8101 aaaaaatcgt ttgttggatc agtagagaca agagttggag aaagtaattt ggttcattga
     8161 tttctatttc tttttttaga tcgttcagta aattctcttt ctgttgatac aagtgtgcat
     8221 attgctgatc atatgtttct aaaaaacgat ggtattgacg gtccaatgct tcaatcaata
     8281 tcggcgattc atgatatttt aatatgagga gagccaagtt atcagtcaga gatgtttttt
     8341 ttagttgatc aagagacagc tctgaagcta gttcctctac aaacgtttcg aggacctcta
     8401 aaaatggaga atgatgcagg cagcgagcgg tttcttgtcc atagttattg ttgtaattcc
     8461 aactttccag aaagcagaaa gaagcaaaag aaagctcagt gtctttaaga taaatacctt
     8521 ccgttaaata caattttttc aatgcagagt catacaggga ggagagtgtg ctgttggtat
     8581 ggatagaaga atctaatcgg caattcgctt ttatacggat cgtattgata aagaaccaac
     8641 atgttccgaa aatctcttct gtttcaaccg ctagttcagt ttgactgagg tttcttaaaa
     8701 attgaaaata atgggattca tggatcgaat aatcctcgaa aaaatagttg ttatgagtga
     8761 aaggaatcag caatcgatga taaaaagtac gaatcgcacg ctcttttcca agaatacaag
     8821 ctgtatattt cgtcaaatcg atctgcaagt cgtaacttgc taaacgctga ttgattttag
     8881 tcacatgtct tttcaatgtc ccataagaaa gcccatggtc ggctagaaaa tcagggacag
     8941 caactttttt tgtaaaaagc agatttttca gcagttcgac actgactgat tgtttgaaaa
     9001 aaatctccca aaggtcattt gttaataaat tttgctggtt ttgcaaactg attcctgctt
     9061 gatcgctgat gatgtcccag ccttcgggca gctgagagcg aatagattga aggtcagaaa
     9121 aaatcgttcg ttcggttgtc cctatgattt cagctaattc atttacggtt atctttgtat
     9181 gattcagcaa ttgttctact aaagaaacat gacgtcgaat atctttttcg gtaatgattt
     9241 ttttcattag tgaatacatc aatcagactc ccttctattc taagaatacg gagaaaataa
     9301 acggtggtca agtttcaact gatttttcaa tcattgttta tttttctgga gcatttactg
     9361 atgataagaa tttcatcatg aacttgaaaa atgataccac taaaatcaaa aaataggtgg
     9421 gcaaacaata ataaacattt taatagtaga tggtagcaag accaacacag
//
LOCUS       DADVXK010000102         9394 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.103, whole genome shotgun sequence.
ACCESSION   DADVXK010000102 DADVXK010000000
VERSION     DADVXK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.103"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(130..777)
                     /locus_tag="KB909_002365"
     CDS             complement(130..777)
                     /locus_tag="KB909_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBB6838336.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="KB909_002366"
     CDS             complement(1056..1559)
                     /locus_tag="KB909_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6838337.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="KB909_002367"
     CDS             complement(1682..2446)
                     /locus_tag="KB909_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBB6838338.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="KB909_002368"
     CDS             2553..2828
                     /locus_tag="KB909_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBB6838339.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="KB909_002369"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="KB909_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6838340.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="KB909_002370"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="KB909_002370"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6838341.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="KB909_002371"
     CDS             complement(5605..6063)
                     /locus_tag="KB909_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6838342.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="KB909_002372"
     CDS             complement(6060..7523)
                     /locus_tag="KB909_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6838343.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="KB909_002373"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="KB909_002373"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6838344.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="KB909_002374"
     CDS             8598..9347
                     /locus_tag="KB909_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6838345.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2791 a         1993 c         1633 g         2977 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt tttt
//
LOCUS       DADVXK010000103         9322 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.104, whole genome shotgun sequence.
ACCESSION   DADVXK010000103 DADVXK010000000
VERSION     DADVXK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.104"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..107
                     /locus_tag="KB909_002375"
     CDS             <1..107
                     /locus_tag="KB909_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HBB6838346.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="KB909_002376"
     CDS             complement(176..904)
                     /locus_tag="KB909_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838347.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="KB909_002377"
     CDS             complement(917..2197)
                     /locus_tag="KB909_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6838348.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="KB909_002378"
     CDS             complement(2338..2940)
                     /locus_tag="KB909_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6838349.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="KB909_002379"
     CDS             3185..3391
                     /locus_tag="KB909_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838350.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="KB909_002380"
     CDS             3703..4422
                     /locus_tag="KB909_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6838351.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="KB909_002381"
     CDS             complement(4503..5186)
                     /locus_tag="KB909_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBB6838352.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5405..7591
                     /locus_tag="KB909_002382"
     CDS             5405..7591
                     /locus_tag="KB909_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6838353.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7937..8347
                     /gene="spx"
                     /locus_tag="KB909_002383"
     CDS             7937..8347
                     /gene="spx"
                     /locus_tag="KB909_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6838354.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            8361..8717
                     /locus_tag="KB909_002384"
     CDS             8361..8717
                     /locus_tag="KB909_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBB6838355.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3363 a         1526 c         1745 g         2688 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata
     5281 tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat agacaacgaa
     5341 actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga aggaaatcaa
     5401 tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa
     5461 gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta cctatgaagc
     5521 ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag aaagtgaagg
     5581 aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca atcaagaaca
     5641 aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag gagctgggag
     5701 cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga
     5761 cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac taaaaaaacg
     5821 agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc atagtatctt
     5881 ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca
     5941 aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac agctgatacg
     6001 taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt ctcggttaga
     6061 ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta aagaaaaata
     6121 tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg gattgctcac
     6181 ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg tactccaaaa
     6241 tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa aatatgatta
     6301 tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg tgaaacggat
     6361 gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga gtatctatgg
     6421 attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc ctaccaaaac
     6481 tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag caaatagatt
     6541 gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac aaaaagaagc
     6601 aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt ggctaatcaa
     6661 acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca tattataccg
     6721 atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata ttccttttgt
     6781 actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc aacatttcta
     6841 tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc aggcctacca
     6901 gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat gcgatcaata
     6961 cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga taagccccaa
     7021 tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta aaacagacca
     7081 gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta tagctaagga
     7141 aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg ctactttcag
     7201 aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa aaacccgctt
     7261 gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc acaaaagtaa
     7321 aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt tgccttataa
     7381 cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac cagtaacgac
     7441 gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa atcgtctgta
     7501 tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga
     7561 aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca gaagtggtca
     7621 gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt gaaatttcag
     7681 cttattttcg aagaagctat ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa
     7741 gaattttgtc acacctccct tatttatttt gaaaatgaga atactattat caaaatagag
     7801 aatatataga aaaattctca ttattcaaac gtaaataatc agttattttg atttttttta
     7861 tattttatta gctaataatt ggtattttaa aagaaattac tgtagaattg gattataatt
     7921 aaaaaggagt gagaaaatga taaaagtata tacttcgcct agctgtactt cctgtagaaa
     7981 agcaagagca tggttgcaag cgaatcaact tgaatttgaa gagaagaata tttttgccga
     8041 accgttaaca gaaagtgaga tcaaaaagat cttggcagcg actgaaggag gagttcaaga
     8101 tattatttcc actcggtcga aaatttacga aaagctgggc atagatttta acgaattaac
     8161 tttaaagcaa atgatcgtct tattcaaaga atatccttca ttattgagac gacctatttt
     8221 gattgatgaa aaaagaatac taatcggatt taatgaagat gagatccggt catttgtccc
     8281 tcgtgaaatt cgatgtgttg ccagaaatct gatctattta caaaacaata acatcttaaa
     8341 ttcataggga gggagccttc gtggaagtga aagtctatgg atcagcgcac tgtgtaacaa
     8401 gtctgaaggc gaaacaatgg ttagaacacc atcaattgcc ttatcaattt gttgacttag
     8461 aagaacgcga tttaagtaca gaagaagcag aagaattatg cagttttgaa gaagtgcaag
     8521 cagaacagct atttgcgact tggtctgagg cttttcacaa cattgcgatt gacctttcct
     8581 gtgtaggaaa aaaacaactg atttttttat gcacacaaca taccaatctc ctcagacgtc
     8641 ctttgattat tatcgatgaa gttctattta ttggatacaa tgagcagttg atggaacagc
     8701 ttatcttaaa taaatagact ttaactgttt taatcaagtc actgagcatt tcatacagtt
     8761 gtaacagtcg aacacttagc atcaagcgtg ttatgtgttc tttttttgac tttatttttc
     8821 tactatagag acatgctcaa tttatgtggt caaaattcaa atctaggtgg ggatatagag
     8881 ttaaaaatat attgacatgt gtaaatttac atgatatatt catttctgtt gttttaagta
     8941 gcaaagcaat aaaatagtat tttaaaaaac atataaaata gttgttgaca tgttagaaat
     9001 gacatgataa gataactgag ttgttaaaaa agaaccactt gtgaagcttg attctatcga
     9061 aaaaaacttc aaaaaagttc ttgacaaata acaaatgata agttatgata aatgagttgc
     9121 tgtaagattt cgaaaaacga aatcaaaaaa acttttaaaa aagagttgac aattacttgt
     9181 ctctctgata tgatataaaa gttgctacgg cagccaaaaa cgaatcgggg aacactcctg
     9241 atgaagtaga cctttgaaaa ctgaacaaag taagacaaac caaatgtgta gggcgtcttg
     9301 attcaattca agacaacaaa ca
//
LOCUS       DADVXK010000104         9258 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.105, whole genome shotgun sequence.
ACCESSION   DADVXK010000104 DADVXK010000000
VERSION     DADVXK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.105"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            97..2037
                     /locus_tag="KB909_002385"
     CDS             97..2037
                     /locus_tag="KB909_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBB6838356.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            2124..4046
                     /locus_tag="KB909_002386"
     CDS             2124..4046
                     /locus_tag="KB909_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBB6838357.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(4326..4748)
                     /gene="arsC"
                     /locus_tag="KB909_002387"
     CDS             complement(4326..4748)
                     /gene="arsC"
                     /locus_tag="KB909_002387"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBB6838358.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGLN
                     PRAIKIMAEDGIDISKQTSDLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDL
                     KDPAQAVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
     gene            5140..6162
                     /locus_tag="KB909_002388"
     CDS             5140..6162
                     /locus_tag="KB909_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HBB6838359.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            complement(6287..6721)
                     /locus_tag="KB909_002389"
     CDS             complement(6287..6721)
                     /locus_tag="KB909_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6838360.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            6836..7810
                     /locus_tag="KB909_002390"
     CDS             6836..7810
                     /locus_tag="KB909_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6838361.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            complement(8208..9161)
                     /locus_tag="KB909_002391"
     CDS             complement(8208..9161)
                     /locus_tag="KB909_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBB6838362.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
BASE COUNT         3003 a         1620 c         1861 g         2774 t
ORIGIN      
        1 atttattcca agaatttcag ttattacgga atcattttgt gcttaataaa aagaaaccgt
       61 ttttatatac tataaatgta gaaaggcggt aggaaaatga aaaaaattat tgcaatcaca
      121 tcctgtccag ttggtattgc ccatacatac atggcagcag aaaacttaga gaaagcgggg
      181 aaagcagttg gcgccgaggt aaaagtcgaa acacatggtt ccatcggtat tgaaaatgaa
      241 ttgactgcaa gagatatcga agaagcagct ggtgtaatca tcgcagcaga tactaaaata
      301 gataaatcac gattcggcgg taaacctttg ataaccgtag gtgtgcaaga aggaatccac
      361 catgcagatg agttggtgag agatatttta gcaggaaaag cgccagtcta taaaagtacg
      421 gaggcaatta tttcttccga aaataaaagt gaatcagaaa atttaggtaa aaaaatctat
      481 aagagtttga tgaatggcgt ttcgtacatg gtacctttcg tagttacagg agggttattg
      541 atcgcgattt ctttaacatt aggaggaaca gctacacctg aagggatcaa gataccagaa
      601 ggaacgattt gggcaacgat gaatagtatc ggaagtatcg ctatggggtt gatggttcca
      661 attctatctg catttattgc gcaaagtatt gcagatcgtc caggacttgt tcctggattt
      721 gttggtggga tgttagcggc aaacggagca ttatatggta gtgatgcgaa tgcgggattc
      781 ttaggcggga tcatcactgg atttttagca ggattcattg ctttaggaat caagaaagtg
      841 cgagtaccga aagctttaca atcgatcatg ccaattattg ttatcccaat tttaggatca
      901 ttggcagttg gttttgtgtt tatctatgtt attggagaac cagtagctct tctatttagt
      961 tcattgactc actttttagc agggatgcaa ggaggaagtg aaattgttct agctatgatc
     1021 ttaggagcga tgattgcttt tgatatgggg gggccgttca ataaagtagc ctttttgttc
     1081 ggatctggct tgattgcaga aggcaattat tccattatgg ggccaattgc tgtagctatc
     1141 tgtatccctc cattagcatt ggggctggca tcattgattt taaaaaccaa atttacgaaa
     1201 acagaacgag aagctggtaa ggcgtcctta gcaatgggac tgtttgggat tacagaaggc
     1261 gctattccgt ttgcttcaac agatccacta cgggtgattc caagcattgt aatcggggca
     1321 atgacaggaa gtgtgatcgc gatgctttca ggagtgacag atcatgtagc tcatggcggt
     1381 ccgatcgtag cggttttagg agcagtggat cacgtagcca tgttttttgt agcagtgatt
     1441 gctggtattg ctgtaaccgt gctaatgtta agaatcctta aaccgacatt acaacaaact
     1501 gcggttgctg cagcaaatgg tgtgacagta gcagatctat cagagactga aacaagtgat
     1561 gtttatacga aaactgaaac ttttgattct atcacggata ttatgtcaga tgaagcaatc
     1621 gttttaggtg aaacagcaac aacaaaagac ggagtaatcg aagatttagt ccaacgttta
     1681 gaaaaaacag cggcgatcac agataaaacc agatttaaag aagtcatcta tgatagagaa
     1741 catgaaagta caacgggaat cggtatgggg attgctattc cacatggaaa atcagcttat
     1801 gttcttaaac caacagtggc atttgccaga agtcaatctg gggtagattg gcattcttta
     1861 gatggaaaac ctgcacatat gatctttatg attgctgtac ctgaaaacag ccaaggtgat
     1921 atgcacttga aaatactgca acgtctatca cgtaaattga tggatgatga cttccgtcaa
     1981 gcactgatgg aagcgccaga taaaacaaca gttcaccaat tattaagcga aatgtaacat
     2041 aagatgaaaa atcgaccgtg atgagacata atagatgtgt tatcatgatc gattttttat
     2101 ttagaaggga gtttctgcac attatgaatc agcgtcagca atctttgatc tatcaattaa
     2161 gtgagaacaa taattatata acaacaaaaa agctagcaga gcatttccat gtgtcagaaa
     2221 gaacgattca tagcgatttg aataccattg aaacttggtt gagagacaaa catctgcctt
     2281 taatgtttga aagaaaaaaa ggtacaggta tcttgttgaa tggtctgcct cacgaaaggg
     2341 aacaactgaa acgagcgctt aatgaagaga ctcaaacaga aatggataaa aaacagcttc
     2401 gtcagttatt gattttccat ctgctagtag caaaagacgg atttagtctt gaagaacttt
     2461 cagaaaaact atatgttgga aaacgtacga ttcgtaaaga attgacagag ttgcaaagct
     2521 tttttgagta tcaccattta cagctagtat ccaaaacaaa actaggaact tttcttaaag
     2581 gcgatgaaca agaaaaaaga cagttgcttg ttaagacatt acgaaatatg cagaaagaag
     2641 atccacaaag tccgtcgttg aaagaattct tcgctaaaga tacattaaaa gttatccaac
     2701 atacattaca agatgttttt tatgaaaacc atttagaaca gccgaatgga ctggctagtg
     2761 tggagattca catctacttt atgctcgagc gaatgaaaca gtaccagaaa gtgaaattaa
     2821 gtaaagacga aaacgaagtc gtggaacaca cccaagcaca aaagttaagt agtcaaatat
     2881 tagcaaaact agccaccatc tatccaattg aattttctcc tgatgaaatc aattatctgg
     2941 ctttgcgtat cgccaatctt tttacaaatt cacaagcagc cacacgtttt caaaaggaat
     3001 ctagcgcact tgctgatcat ttgatcgaac aagtggaaca gtttctaggc tattcattaa
     3061 aagaagatca gctactaaaa caaaatttaa ggtctcattt atcttcaact tattttcgac
     3121 tccattatgg tttgcagatt tctaatccat tgacgaaaaa tgtgtttagt acgtacacac
     3181 aacttttctt agttttacag ttaattttag aagattattt tgaaaaggaa aatttttatg
     3241 ttccacaaga ggagacagct tatttaacga tccatttcca agcagcgatc gagcgacaca
     3301 aacatcagaa aagtagaaga tatcaaacgg ttttagttag tgaatattca aaagctatgg
     3361 ctacttttct cgaagcacgg ctgaacagag aacttccaga attaacgatt atggatctag
     3421 ttgaatataa gccagaatta aagagacaag attttccctc tgttgatttt atcttggcta
     3481 cgttaccatt taaacatata agcattccag taatcgagat ctcaccaatg atcacagaaa
     3541 ctgatctagc ctatttgaca aaatatatgc tggagcatgt gcctatcaag aagaaaaaaa
     3601 catttgatct agcaagcttt actcatccat ttctgatctt tcctcaactt gaacggacag
     3661 acccagccga tattttaaac tttatgggaa acgtcttagt ggaacatcat tatgtggagc
     3721 cggaattcat cgattctgtc ttggaaagag acagtcactc cagtactaga gtagcaccat
     3781 ttgtaacaat ccctcacggt aatccgctgt atgtgaagca ttcgatgatt tctattgcta
     3841 caatgaaaga accagtccta tggcacgggg aacagatacg tatcgtactg ctattagcaa
     3901 taaagaaaaa tgatttgaaa catgcagagt tcaaaaaaat attttctgtt attcactatc
     3961 tagaaaagca gccagaacaa atggctcagt tgatgcaatc caatcatccg ctagaaatct
     4021 taacgttgtt atctagttat gaataagtag cgattaaaaa actgccttta tatttataat
     4081 aattctatct atttatttgg aagtagaaaa ctaaatacaa aaaaagagga tgtggccaaa
     4141 gttgtggcac atccttttat tttgagtttc ttataatttt ttatagttgc ttacgatgtc
     4201 ttgactactg gtaaacggtg ttcaagagac aatttgtcgg caataaggca caattttgta
     4261 aaatatggaa agctattttt ttaacattgt ttcttagtgc ttgaaaaatc attttgaata
     4321 cttctttata cgatcgatgt acgttgattt aagtctaaaa cttttctttt gattccttct
     4381 ctgacttttc tgaattccgt taatatttct tcttcgctcc cgacagcttg tgcaggatct
     4441 tttaggtccc agtgaaggtg ttcgtgattg tttggaacgg cagggcactt gtctttggca
     4501 tcaccacaaa gtgtaatgat caagtctgcc tgagtaaagt aatctctatc aatcaaatca
     4561 gacgtctgtt tggaaatatc gatgccgtct tctgccatga tttttatagc tcttggattc
     4621 aagccatgtg tctcgatccc cgcacttctt atctcaaaca ttgaaggaga caagtattta
     4681 cgcgcgtagc cttctgctat ttgactgcgg catgaattgc ccgtacataa gaaatagatt
     4741 tttttcattt gatttcctcc gttatggatt agtaaatgtc actgtttatc taaagtaaac
     4801 tctatgtgat ggagcgaaaa aacaatgggt ttcttagttt atatatttct ttttgttcag
     4861 cgtataaatc gatgtgtaca aagaactaat cttgtctttt ttaccataaa tacatgttag
     4921 aaacaatcat tttgagtcaa aaatcaacga tgtaacagac tgttaaaaga gattaagaca
     4981 cggcagatga tgaagaaagt aggggtgtag taagccgata catttcttga ttgtgaggcg
     5041 agaacaatta ttcgtctttt aagaaaaaaa gtagtagaat cagttcatat taaaaataaa
     5101 aaaccttcca tttttgtagg tttaaaggag gtcattacct tgaaaaaaat cggcttttta
     5161 agctttggac attggatgga gcaaggatcg cttgtgaaat cagctcaaga tgcttatttg
     5221 caatcgattg atttagcggt ggaagcagaa aaaatcggag tggacggagc gtttttccgc
     5281 gtacatcatt ttgcccctca gattgggtcg ccgtttcctt tgctagcggc aatcggcgca
     5341 aagacaagta agattgaaat cggtacagga cttattgata tgcgatatga aaacccttat
     5401 tatatggcag aaaatgccgg attgacagat atcatcacgc aaggaagagt gcaactagga
     5461 gtggggcgtg gttcacctga acaagttcta gatggctgga aatactttgg ttatgattac
     5521 agtgaagaag aaatcaaaga ggtaacacgg gaacgcaccc ttgaattctt ggaattactt
     5581 gaaggaaaac catttgaaga accaaatcct caaccaatgt tcccacaagg atcaggaaaa
     5641 ttacggatag aaccttattc agaaggatta cgacaaagaa tctggtgggg agctggttcg
     5701 cagcaaacgg caatctgggc agcacaacat ggaatgaatc tgcaatcatc tacattagtc
     5761 aattacgaat cccacgagcc attccatatc caacaagcaa accaattacg tgcgtataaa
     5821 gaagcgtgga agcaagcagg tcatgatttt gaaccaagaa cattagttac tcgctcgatt
     5881 cagccaatca ccactgattt ggatcgacgc ttatttggac aagacggtag tccgcaacaa
     5941 gatgctgtcg gctatcttgc ttatcaccga aacccaacga tttttggaaa aacttttgct
     6001 ggtgaacctg atcaattaat caaggagcta gctgaagatg aagcaatcaa agaagcagac
     6061 acagtacttg tcacgattcc taatactttg ggggtagaat ataacatgca cttgcttgaa
     6121 acaatcgtaa aagatatcgc tccagaatta ggatggcggt aaaaaggata tttttgtaag
     6181 tgcaggatac ttgagtgaaa aaataaacac ttctaacaat cagttagagg tgtttattca
     6241 tgttttcatg aagttcatag agaaggagag tgagttatcc gtttgttcaa tgagaatgta
     6301 cataagcttc ttttacatgt tggggtaaat catcaggaat cattgtcaat acggcttctt
     6361 cattgccggc ttttattgct tcttcatagt accagctttt gtagtttagc atagcgagta
     6421 ctctttctaa ttttgctatt tctttttcta ctacttcttt ttgtttttca aatagttctt
     6481 tacgaacctc aaatgtctta ctgccttctt tgctccattc catgaattgc ttaatgtctt
     6541 ttatttctaa accagatttt ttcaaacagt caatgactct taaagcctct aactcattct
     6601 ctgaaaattt tctaatacca gaaacacgct ggatatcagg aaataatccc tctttgtcgt
     6661 aataacgtaa agtagaaaca ggcaatccaa acatttcaga cacttgtcca atggaataca
     6721 taaaaaaatc ctcctaaaat aaaattttta ccttgaccta aagtcaagtt taagttttat
     6781 cataataata cattcaaaaa caaatgtcaa ttttgatcaa aggagagtct agaatatgaa
     6841 taaagaatta aacatcacac aagaatggga caaagtattt ccaaaaagca atcaagtcaa
     6901 tcatcgaaag gtgagcttcc cgaatcgttt tggtatcaca ttagtcgctg atttatatga
     6961 accaaaagaa gtaagtgaaa agaaattgcc ggcaatcgct gtgagcgggc catttggtgc
     7021 agtgaaggaa caatcgtctg gtctatatgc gcagacgatg gctgaaagag gctttttaac
     7081 gattgcgttt gatccatcgt ttacaggaga aagcggagga gtacctcgat atgttgcttc
     7141 gcctgatatc aatacggaag atttccaagc ggcagtagac tttttatctg tacaaaaaaa
     7201 tgtaaaccct gagagaatcg gaatcattgg tatttgtgga tggggaggta tggcattgaa
     7261 tgcagcagct atcgatacgc gggtcaaagc aacagttgtt tccacaatgt atgacatgac
     7321 tcgagtaaca gcaaatggct acttcgatgt tatggatgaa aatgcccgat atgaaatgcg
     7381 tgaagaatta aatgcacaac gcatcattga tttcaaacaa ggggactacg cacgtgctgg
     7441 aggtgtggtt gatccgttgc ctgaagatgc tcctcaattt gtcaaagact atcatgcgta
     7501 ttataaaaca gaccgcggat atcatgtccg ttctttaaac tccaatgatg gttggaatag
     7561 gacatcaggg ttgtcactta tgaatgcaaa actattgcat tatattccag aaatccgtca
     7621 tgcagtctta gtcattcacg gggaaaaagc tcattcacgt tactttgggg aggacgcttt
     7681 caaagaacta aaaggtgaca acaaggaact catgatcatt ccaggagcat cccatacaga
     7741 tctatacgac cagacagaca tcattccatt tgaaaaaatg gcaacattct ttgaagagaa
     7801 ccttgtgtaa ccaaaaggat ttaatctaaa agagattatg aaaaaactgc cctgcatcaa
     7861 gtaataagga cagccaaaaa agctcctcat ttttgacttg gttggactca ttagcgtaga
     7921 tgcaagcttt tgaacaccgt ttataccaag aggtcgtgag cctgccgttt aactctgagt
     7981 cacaaggagc aatttcaaaa aatagcttct catgtttgtt gaatattgtg acttgtgacc
     8041 gaggagttgg caggagaaca ccgtttattc gaaaaaagga ctgtgacaat gtatcgactc
     8101 ccaaaagtta gaccaaaaaa tctaactttt gggggtcggt acacacgttt tttgtcacag
     8161 tctctttgtg tctcatttca tataaacaat tatttacttt gtactattta tttcatttct
     8221 gtgattttaa tgctttttgc taaatttttt acatcagctg gaataacttt cccgacttct
     8281 gattgctgtg cattcgacat gccgcaagcc attgcgtacc ttacacattc ttttaaagga
     8341 taattctgtt ctaatgaatg agcaaaacct ccaacagtgg catccccaga gcctgttgta
     8401 ttaatgatag gaatcttagg gatctcaaca ttccaaaatt cttcttttac tttgactact
     8461 gcaccatacg agccgcaaga aatcatgata acatcgatat ctttaaatag tggatttgtt
     8521 tttagatggt gttttatgtc gcttttttga gtaatttttt gatggatgat atctgaaaac
     8581 tcatggatat taggtttgat gaacatcggt ttatacttac ttgctaagac ttcacggaga
     8641 tgttgtccag atatatccat taatatatag gtggaaggat ctatttgttc tttgatatat
     8701 tgtaataatt tagcatacaa aaagggatct ggattgttaa cagaaccatt tattgtaatg
     8761 actgaaaggt aattattttt actgattagt ttgatatcat tcattaattt tttgatagta
     8821 gtatctgcta tttcaggacc agcttccact agctctgtct gcgtttcatc atcatgcatg
     8881 atcgtgacgg cacctcttga ttcttctgca ataggtaaaa aatgcaaatc aaacaaattt
     8941 tcatttttca gcatatcttg aatcatactg ccaaaataac cgcccaaaaa ccctgttaaa
     9001 ataactgatg aacctagtag agcagaagct cgtccgcaat tgattccctt gccgcctaca
     9061 tagcgtaccg gagaatcaaa gcgtgtcatc gtacctaatt caaagtgttt tgtaaaataa
     9121 atggaatcaa tggatgggtt catcgtgatt gtcagtatca tttttgggct cctttaatat
     9181 tgttaagtat tttgaataat gattgaaatc ctgttctgat aaatgattat cggttattag
     9241 ataatcaaaa tcggttaa
//
LOCUS       DADVXK010000105         8850 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.106, whole genome shotgun sequence.
ACCESSION   DADVXK010000105 DADVXK010000000
VERSION     DADVXK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.106"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            63..1277
                     /locus_tag="KB909_002392"
                     /pseudo
     CDS             63..1277
                     /locus_tag="KB909_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1456..1785)
                     /locus_tag="KB909_002393"
     CDS             complement(1456..1785)
                     /locus_tag="KB909_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6838363.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1775..2047)
                     /locus_tag="KB909_002394"
     CDS             complement(1775..2047)
                     /locus_tag="KB909_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBB6838364.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2498..3301)
                     /locus_tag="KB909_002395"
     CDS             complement(2498..3301)
                     /locus_tag="KB909_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6838365.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3279..4403)
                     /locus_tag="KB909_002396"
     CDS             complement(3279..4403)
                     /locus_tag="KB909_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838366.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4419..5234)
                     /locus_tag="KB909_002397"
     CDS             complement(4419..5234)
                     /locus_tag="KB909_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6838367.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5224..6096)
                     /locus_tag="KB909_002398"
     CDS             complement(5224..6096)
                     /locus_tag="KB909_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6838368.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6181..7470)
                     /locus_tag="KB909_002399"
     CDS             complement(6181..7470)
                     /locus_tag="KB909_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6838369.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7698..8342)
                     /locus_tag="KB909_002400"
                     /pseudo
     CDS             complement(7698..8342)
                     /locus_tag="KB909_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2742 a         1883 c         1409 g         2816 t
ORIGIN      
        1 caaaatcaat tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag
       61 ccaagaaaaa gacgttggtc gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa
      121 gttgtggttc tactgtggta gatggaaacg ggaaagcaat tatagtgaaa aatgggaaga
      181 aggaaacgat tgtccgtttt gaacaataca atcatatgcc tttggttacg cgcctaaaaa
      241 agcaacgcta tacctgtaaa aactgtcgta cccattggac ggctcaaagt tattttgtcc
      301 gactcagcca ttcaatcgca gatcatgttc gatataaaat tgcttcttta ctgactgaaa
      361 aagtatcttt gtcttttatt gcgaaaagtt gtcaggtatc tttgactacc gttactcgta
      421 cattgaaaga gtttaaaagc tatttaccaa agccttctaa gaagattctc cccagagtat
      481 tgatggttga tgaatttcgt tcgcacgctt ccatagaaga taaaatgagc tttatttgcg
      541 cagatggtga aacaggaaac ttaattgctg tcttgcctac gcgtaaatta cctcgattaa
      601 caagctattt cttaggctgc accaatccag aagaagtaga attcttagtc acagacatga
      661 acgccgctta cttccagctt accaaacgtg ttctgccaaa tgcgaaagta gtgattgatc
      721 ggtttcatat tgtcaaacac atgaatcagg cactcaatga gttgcgtatc cgtgaaatga
      781 atgagcttcg taaagcagga cagaaaagtc aggcagaaaa actgaaaaag aactggcgct
      841 ttctgctaaa aaatcgtgca agcatcaacc attatgagta caaaacatgg aaaagtttcc
      901 gagcaccaaa atacccattt ctcactgaag caatgatgat tgatcgattg cttgagtttt
      961 ctgcgcctct aaaggaggcg tatccctttt ttcatgaatt agtcgaagcc tttcgagaca
     1021 aagaccctga cttatttttc tccttattgg cagaacttcc cgaaacgtta gatgacggct
     1081 ttcgggagaa gcttcaaaac cttctgacct atgaagaagg tatcaccagc gcaatgatct
     1141 atccttattc caatggaaaa attgaagcga agaataccca cataaagaca atgaaacgag
     1201 tatcctacgg atttaaatca ttcgagaaca tgagaattag aatctttttg atcaatcaat
     1261 taatcaatgt aagataacaa aaaatctgaa ccagaatgtg gttcattctg acccggattt
     1321 gattttgcac aactcatcag tccttattga caaagagcca aaaatctgag ccagaatgag
     1381 gttcattctg acccagattt gattttgtac aacccatcag tccttattga caaagagccc
     1441 ttctttttag tattattata attcttccat gcgttcttcc agtcgctgta aatcgcttgg
     1501 acttaattcc ccaatttttt tccatttgac ctttttgttg tttttgggta attcgtttag
     1561 agttcctacg tcaatccaag attctttttt tagtcctgcc tgtttccaat cccttatttc
     1621 aacgtatttc agctttattt tatcggattt agtatgatat tttgaagtaa ttgacagaaa
     1681 cgaaattgtg tccagtccat tttttagaat atagacaggc cggcgtttac cgccctctgc
     1741 agctgtgaaa gcaacgtaga cggttgctat atcattagta ttcatcttca ttgaaccatt
     1801 cttcaatttt ttcgtcagtg tctagttttt ggacaggcaa tttttccgct aatctttgaa
     1861 tattatggat tcgtttactt ttttccgaca attcaataga aaatgggatt tttccttgct
     1921 caacaatttg cttataaaaa acggtgacgg ctgttttggg gctcatgcct agttcatcaa
     1981 taatgctttc tgcttcattt ttcaattttt cgtccataga aatttgtaac ttagccattt
     2041 tctccacctc tttctgacaa acacattata tcacggaaag agttcaaatg gaattaatac
     2101 aactactttt gaactccttg aaatgcagtg tatttatcta aatataagga aaggatatag
     2161 tgctaaatgg ccttgataga tagaaaagtt tcaaaatccg ccacagcgat aattgaagcg
     2221 aacactcaac gacacacaga acaggaaaag actcctaaaa gaaccaaatt aactaggacg
     2281 tgtctgaaaa ctccacaaag atgtggtatg ctctggtaaa aaacgaatgg cacaaccacg
     2341 aagaccgata tggttcttgg aaaactttct ccaccctttt tgtaattgga gggatagtgg
     2401 tttattgata gcgattttcc aagttcttca agtggaacca gacattgagc accacggcta
     2461 aaaagtgaat gaagtcttta tttttaatca ataattttta atgattacca gtaattggtt
     2521 ttttcatgcg ccctatttct atttgatgtg gagttaaata atgctgataa gtaaaaattt
     2581 ttccgtcaat taaactgcca ctagtgaatc ctgttctatt ggtaaaaaga gaatagtctg
     2641 ggtattcatc tacaccaaat gataaagatt cagccataaa ctgtttttta ccagcaaatt
     2701 cagcactgct accttgatgg atatgtccta caaaaatacc taaaatatca ctttcggcaa
     2761 tcaattcagc aaaaccttcc ggaacttcag ttacaataga tggatcttcc cacgacaatg
     2821 gatgatgaac caataaaatc gttccctttt cagcaggtgt acccaaccac tcttgtaatt
     2881 gaatcatctg tcctatcgat atttttcctt cgtgctgggt atcttgagca gaatccaagg
     2941 aaataattcg taacccattt tgattcgtac aatggatata ctctcccgtt tcattgcttt
     3001 caacactcat tccttcaaag aaaacactgc gacgatcatg attcccacga caaaaatagt
     3061 aaggtgtggt tgggaaatat tgatccaaca ttttccgtaa gacttgataa tcagaaatcc
     3121 ccccttcatg tactaaatca cctgttaata gaataaaatc gtacactgtt aacgagagtt
     3181 cttgtaacaa tttttccaat gccaactgtg gatttttaat tgttggaaat agttcagcag
     3241 taaacaagtt agtttgatag ttttctctaa aatggatatc agagagatgc aaaaagcgca
     3301 tggctattcc ctctttcttc aataaaataa tcaggatatc ctaaattttc ttgcgtctga
     3361 taatcaaaaa aatgcattct ttcaggttct atgcggagat tgactgcatc accaatctgc
     3421 caagtaggtt tttcattaag gacaatcatt tctataccat cgactttaac ggtgtacgca
     3481 taactttgac ctaatagctc acgatacttc acttgaccgt gtaaatcgct tgtttctttt
     3541 gaaaaggtta cgtgttctgg tcttatgcct aaatacaatg agccactaac ctgaagaagt
     3601 tgtttttgcc aagctggatt caatgttaaa aattgactgg ctacctttaa tgttccttga
     3661 tcataagtaa ctggcataat attcatgcct ggcgaaccaa taaaatttgc agtaaaagta
     3721 tttttaggtt tcgtataaac atttttcggc gtatcaatca tctgaattct accttcattc
     3781 aataaaacaa tccggtcagc taacgtcatc gcttcaattt gatcatgagt gacgtagaca
     3841 aaagtttgtt tataacgttg atgaattttt accaattctt ttcgtgcatc caatcgtaaa
     3901 cgcacatcca aatttgataa cggttcatct aataaaaaat aattactccg tttaaccacc
     3961 gcacgagcca atgctacacg ctgccgttgc cctcctgaca aatctttagg aagtcgatct
     4021 tggtatggcg ttaaacctaa catcttcaaa gcttcttcca aacggtgctg aatgtcagct
     4081 gtcttaattt tattcgccct taatgcaaaa ataatattct cctttacagt catgtgagga
     4141 tataaagcat aattttgaaa aaccattgcg atctctcgtt ctccacaagg tagcttattt
     4201 gctagttgtg tacctaaaaa aagctctcca ctcgtaattt tttccaaacc agcaatcatt
     4261 ctcagcaaag tagattttcc tgaaccagat ggtcccagta acacaattcg ttctccagcg
     4321 gccacagcta aatcaatttc ttttaaaatg gtatgttctc catatttttt tccgatattt
     4381 cttaattcaa gcgtttctcc catgatttgt cctccaattt atttaatacc tgcagaaaca
     4441 aaagtcccga taatatattt ttgaaaaatt gcatacaaga ctaacggtac aaacattgta
     4501 attaaactaa tcgccattgc tacggtaaaa tttgtcccac cttcagaact aatataggtc
     4561 tgcatcgcca acggcaaagt ataattatct actgtccgta aaattaatac cggccaaaca
     4621 tactcattcc aagaggtaat aaaaaaccaa ataccggtag aagtaatcgc atgtctagta
     4681 agaggaaaaa caattttact catgacggtt gtttgtttga tgttatccaa tgccgccaca
     4741 tctagaaggc tcactggaat ttcccgcatt gtttgcgtca ataaaaaaat gcccatcgca
     4801 tcagcaaatt gtggtattat cacaccccaa gtagtatcaa ttaaattaag ttttgcaatc
     4861 aacaaataat taggaatcat cgcaacagta aaaggaatga acatcgtacc aatgatgata
     4921 aagtaccaga ttttcttccc tttgattcgg caataagtaa aactatatgc cgcaaaaaaa
     4981 gctacgccta acttaacaac cgttataatt gtagcaataa aaaaagtatt tctcgtaatt
     5041 ttgataattg gaagattttc gaacaaatag caaaaatttt ccaaggtaaa cggctgtggt
     5101 atcaaactag taatcgtctg ataggcatct ttcaatggct taaaagaatt ggccataata
     5161 aacaataatg gatagataat aatgattatg atgaacataa ataagagatg tggcaaccag
     5221 cgtttaattt tcatagtaaa cccccttttc cacaaattta aatattaccc ctaagaaaac
     5281 agcaaatatt aataaagtta aaactgaaat tgctgaagat tctccgactt tatacatttc
     5341 aaaagccttt tgataagcat aatagatcac gtttgcacta ccattattcg gtccaccacg
     5401 agtgatgatc ttaatcggag taaacacata ctgcagacct tgaacaatgg tcatcaccaa
     5461 taaatatagt cctgtcgaac tactcatagg caacacaatt gtaaaaaaaa tgcgccagat
     5521 gggtacacga tccaacttag ctgcttcgat catctcttga tcaattccca caattgctgc
     5581 aaaaatgaca atgaaattat aaccaaaaac tttccaagca gtaatacctg caatcacagc
     5641 aattacccaa ccttgtaaat tcatccacat aggcagtctt aaaccaaaat ttcccaacaa
     5701 gacagcaatt ggtcccgata ccggatttaa tatccatgta aaaaccatcc ccgccactac
     5761 caaagaaatc acagctggaa taaaaaataa tggtttatac aaattctgcc ctttttctat
     5821 aactattcct aataaaaagg atgtaatata tgggaacaca cagctcagca agacaaatag
     5881 aacggtatag gacaaagtat tcttcaacac tttatgaaag actggatcag tcagcacctt
     5941 tacatagttg gcaaagccaa caaattcttt agtgggggcc accatattcc agtcaaaaaa
     6001 actcaaatag atcgtataaa tcaatggata aaaaacaaac acgcccaaca aaataattgc
     6061 tggcgccaga tacaaataac ctacatagcg cttcatttcc gacagcctcc tcatccttat
     6121 gtcaaaagca gacgaccttg tttttccttt cttacaggcg ctgtcgtctg cttgctttgc
     6181 ttatttgagt aactcattaa tttccttttg agtagctttc atcgtttcat tgacggaatt
     6241 acctgataaa attttatccc gcatatccaa caatttttgt tcagcttcta atccagcatc
     6301 tccaggaaat gaactccaac tgaccatctt atccatctga tcaattgctg gtatcatcat
     6361 ctgattttca gctaagaaag cttttaatcc attttgggcg tctgcaacat ctttacgtgg
     6421 tggtaaataa ccagtacctt ctgtccattt agctaaagat tcaacactat aaagatattt
     6481 taagaaatcc caagttgctt cctttttctt atccgtttgt gatgtaacag ctaacattgc
     6541 gccaccagca ggtagtttaa cttttttccc ttcccaactt ggtgactcaa ctgctttagc
     6601 agtaaaagta ctattttttt gaatgttgtc cctttgagca atagtggtat agaccatcgc
     6661 gacgttacca tcaataaagc tttgcacacc ttgttcccac gtagtgtgta atgccgtctg
     6721 gtcttttacc atcctttgat ataattcata agcagcgata ccatctttag aagcaaaggt
     6781 agctttgcca tcttttatta cacttgcccc attactttct aaaattgctt gttgtgccca
     6841 attatcagca ggttcttgaa tatacacgcc atactttcca gttttttctt ttattatctt
     6901 agaaaaagtt tgaacttctt cccaagtttt tggaccattt tcatccaagc ccgctgcttt
     6961 taatatatct tgatttaaat ataaaaccgg attactaatg gagtaaggaa tacccacttg
     7021 tttaccatct ttttcagaca gtgccatgat attgtctaaa aaatgatctt taaaataatc
     7081 agcattatcc ggatccactt cttctactaa agattgagga ttagtatatt tgaaattttc
     7141 tgcaaaataa tctttaaaag cccatcccac ttgtactacg tccggtattt ctttggaggc
     7201 aacagaagct tgtaaatttt gcatcaagcc tttatacata tcaggattat attttgctac
     7261 aaccttcact ttgtcttgag attgattgta tttatctact aattcattca ctgtttttcc
     7321 acctagggta tccgcattaa catgccaata ctctatcgtt acacgaccct ccgatttttt
     7381 tgttgtcttg gtattcccac taccacaagc tgccaaagag atgacactta aaacagacac
     7441 aacccctata acaagatttt tctttaacat aacattaact tcctcctaat ttctttatgg
     7501 ccatttttct aatcaagaaa tattatgaac taccaatgta aatttctagt taattttctg
     7561 taaataattc gaaatttgtg catttcgggg tacagggtca ctggacatat ccatcaagct
     7621 aagaataaag cccccatatg gtcatgtatc ccatctccaa atctcttaac tcctctgttt
     7681 tgattataaa atagtttatt ctgtgctcct ttcttccata aataggccca tgcacaacgt
     7741 gaggttatat tataaacacc acagcgcgca aggtactcaa tcgtttctag ttcattgact
     7801 gtccatacag aaaatgtcaa tcctagctgc tgccccactt cacgggccaa cttagttaac
     7861 catccttcat gaatattgac gatttgaacg ctttgatagg ctaatttctg taaggtatcg
     7921 atcaaatctg cttcggtaat atccccaagt tttttccctt cgaactgatt ttcaatatta
     7981 taaaatatat gctttcccca aatcgcagcc caagataatt gtacatagcc actaagaaca
     8041 atttgtggcc agatttgata ggtttgtgcc agcgaaaaaa cggccatttc caatccctct
     8101 tcttttaaat cacagttaat ggtcatggtt gccttctcat tggccactgc ttgaaacacc
     8161 tgctcaaggg ttaccgaatc tgggacaact tcttacctgt catgggctag tattagcgta
     8221 ccatctgttt gctgacgcac atctacttca aaacaaagct ggcgatccaa acaaaagcga
     8281 agaaatgccc agctattctc ctccgtattg tcactaccag agtgtgcagt gatcatggtc
     8341 attttgaccc ctcctttaat tccgtgattt tctcccacac gtccactata ccgatgaagc
     8401 gttaatttct tgttaatttc ttgtaaattc cctgcgtttt ttcagtaaac tagttgtaaa
     8461 tcttgcatgc tccttcctac gaactcatga atcgtcgatt ttgcccttct agctagtttc
     8521 accaattaag tagttctaca ttccccgctt ttaacctact acaccttttt ttgttttcag
     8581 ctattccttc ttcttgctga aagtccttga ggttctttct tacaggatac catcaaggtg
     8641 ttcaatggct tattcccatt gaatgaccga gacttactat cagatttctg ctcgttgaac
     8701 caagtctttg atacaggatt tcttccgtca tcttctcaca aataccacct tgcgtttctc
     8761 tagcgattgg tcgatgtgca ccctcccagt ggactgtcac tacccctttt tgctatgcct
     8821 agcccacaaa aaaagctgtc ctcacagaca
//
LOCUS       DADVXK010000106         8494 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.107, whole genome shotgun sequence.
ACCESSION   DADVXK010000106 DADVXK010000000
VERSION     DADVXK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.107"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..323
                     /locus_tag="KB909_002401"
     CDS             <1..323
                     /locus_tag="KB909_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838370.1"
                     /translation="KHRKKEMPIRCPNCNEVIKRKLSHGYFVSYELYEESKINLKKKP
                     KYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGNICPGFMDQIIENESIESIENYVPV
                     DLPK"
     gene            complement(496..678)
                     /locus_tag="KB909_002402"
                     /pseudo
     CDS             complement(496..678)
                     /locus_tag="KB909_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            665..862
                     /locus_tag="KB909_002403"
     CDS             665..862
                     /locus_tag="KB909_002403"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838371.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(905..1480)
                     /locus_tag="KB909_002404"
     CDS             complement(905..1480)
                     /locus_tag="KB909_002404"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6838372.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1635..2161)
                     /locus_tag="KB909_002405"
                     /pseudo
     CDS             complement(1635..2161)
                     /locus_tag="KB909_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2618..4129
                     /gene="gadC"
                     /locus_tag="KB909_002406"
     CDS             2618..4129
                     /gene="gadC"
                     /locus_tag="KB909_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBB6838373.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            4142..5542
                     /locus_tag="KB909_002407"
     CDS             4142..5542
                     /locus_tag="KB909_002407"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBB6838374.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(5707..7142)
                     /locus_tag="KB909_002408"
                     /pseudo
     CDS             complement(5707..7142)
                     /locus_tag="KB909_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            7535..8128
                     /locus_tag="KB909_002409"
     CDS             7535..8128
                     /locus_tag="KB909_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBB6838375.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(8112..>8494)
                     /locus_tag="KB909_002410"
     CDS             complement(8112..>8494)
                     /locus_tag="KB909_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6838376.1"
                     /translation="FSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKG
                     CPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVG
                     YRNQRLAQRILDNELGCANASEAV"
BASE COUNT         2694 a         1433 c         1537 g         2830 t
ORIGIN      
        1 taaaacatag aaaaaaagaa atgcctatac gttgtccaaa ttgcaatgaa gttattaagc
       61 gaaagttgtc tcatggttat tttgtcagct acgaactata tgaagaaagt aaaataaatc
      121 tgaaaaaaaa accaaaatac tataaaaatt tgaaaactgg agctattata actgaaaaag
      181 aatttaaaaa tttagtgact gaagaagaaa gcaggtttta taatttgtct ggtaatattt
      241 gccctggatt tatggatcag attattgaaa atgagtcaat tgaatcaatt gaaaactatg
      301 ttcctgttga cttaccaaaa tagaaaaaat aatcctgttt ttacagtgaa ttattttaat
      361 tttgattttc aataaaaata tattacaata ataatcgtaa tagctaatga aacaatttct
      421 caatcttttt accactccaa acagggagcg tcaataattt tgtgtaaata actcgtcctt
      481 ctgcaaaata atgggttact cagtaaacat tgaagctaat gtatccgtca cttgttggaa
      541 gcctttatgg cttctattta agaatttttg attgtatgta tcaaagatgg atactaggaa
      601 acgctctagt gattcttcat tttgaaactg ctcttttctg cggctgtatt tcttgatttg
      661 tttattgaaa gattcgattg tagaaccaga aggaatggag aacacttttg aactttacaa
      721 caaaactact gttgataaat taattccaat tttagttcca actgatttaa atggtcatga
      781 tgttttactt cgttttaacg gatttttagg tgaggattat agatacctaa aaatttctga
      841 tcctcaacct ttaacagaat aataaaaaac gtgtaatcaa ttatttgatt acacgttttt
      901 tatttcaatc ttcgttgtag tagtggttgc gacataccga aaggtaatct tcattacctc
      961 ctactacaat ctgttcacct gaataaactg gaataccatc aacaatacga gcattcatta
     1021 cagccttttt attgcaaaaa tggcaaatag ttttaatttc ctcaatttta tcagcaaatg
     1081 tcaataatgc ttcggatccc ttgaagagat tattttgaaa atcattcttc aatccatagc
     1141 aaattactgg tacttcctca ttcattacga taagtgatag atcaataata ttctctctac
     1201 ttaaaaattg agactcatcg accaaaatac aatcaacttt tccgtactga tcaataatct
     1261 ccactaattc tccgtacaca tccatttcag aagtaattgc aatagctggt ttcgaaacac
     1321 ctatacgact ctcaactttt ccaaatcctg atcgagtatc tattgcgctt gtcattatga
     1381 taactctctt cccttgttct tcataattat gagccacttt cagtagctca atactctttc
     1441 cactattcat tgttccatat ctgtaaaata attgtgccat taaatttatt cccttctttt
     1501 acaattcaat tattccttaa ttccatctgc ttttatgcag ctgctcgttt attccttgat
     1561 atgtctataa catctactat ccctaaaacc aatttataag ccattagaga tggtattcct
     1621 gaacatctct catattgttt tttgagtggt atatcatctg aaaaactgaa ggaatcatga
     1681 aaatagcgac atacttatca tttagagttc taactttaaa tgcatttact tcttcagtca
     1741 gcactttagt catgttggac atggtttggg gcgtgtagtg atgcccatac attttctcaa
     1801 tcaagtctgc gatttccgac atggtaatac cttttcggaa gaggtgaatg acggtctcct
     1861 ctaatgtgtc attcgtccgt ctataagcag gaacagtctg ttgcttgaac tcgccattgc
     1921 ggtcgcgcgg aatctggaga tgaagttccc catactcggt cttgaccgta cggtcatagg
     1981 agccgttacg agaattaccc gtgttaaaac caatgcgatc gtacttttcg taatcgagga
     2041 aagccgttaa ctccgttttg agaagcgtat tgacagcttt ttccaaatgg acacggaata
     2101 atccattcaa atcgcctttg ttcgctagag tctttaggat ttctgtagta aaatcgttca
     2161 tatggaagtc ctcttttctg tgaatgtgtt gtggtaactc tattctacag aagggacttc
     2221 cttttttcta tttacacaaa atattttaca ctctcaacaa aagtatcttc gattaatact
     2281 tgctcaagtt atgtgcagct acgaaaaagt aggtaccgag gtactttctt tttcgcagct
     2341 ttttttggac ttatgagaag tacattcgct ggaagaatac gatataaaac gagctttttc
     2401 actaaagata ttaatagagt gaaagaaaca agcttttgtt gtcagttttt tcacttttct
     2461 aaaaatgaaa ataaaaaatt ctggaagtgg agaagaattt tgcttgctat actttgtctt
     2521 gtagaaaaga ggtagacaaa ataatgcaag ctcaaataag cgattttcca taaccttggt
     2581 aggaatgaca aattaaatag gaaagggaag taataatatg aataaaaaaa agttatctct
     2641 attcggtttt tttgccctga cagcttccat ggttttgact gtttatgagt atccgacctt
     2701 tgcaacatca caattacatt tggttttctt tcttcttttg ggaggtattt tatggtttct
     2761 accagttgct ttatgtgctg cagaaatggc aacagttgaa ggatggaaag atggtgggat
     2821 tttcagttgg gttagtcaaa ctttaggaga acgttttggt tttgcagcta tttttttcca
     2881 atggtttcaa attacagtag gttttattac aatgatctac ttcatactag gagcgctgtc
     2941 gtatgtaatt aattttccag agcttaatac agatccattt atcaagttta ttggtgtatt
     3001 agtcattttc tgggtactga ctttttcaca gttgggcggg accaatcgta ccgctaaaat
     3061 tgctaaagca ggatttgtca ttggaattgt tattccttcg atcattctct ttggtttagc
     3121 agcagcctac tttatcggcg gtaatccgat tcaaatggct attaatgcga aagcttttat
     3181 tcctgacttt tctcagcttt caactttagt agtatttgta tcttttatat tggcttatat
     3241 gggcgtagaa gcttcagcat cacatattaa tgagctggaa aatccccaaa gaaactaccc
     3301 attggcaatg tttttactag tgattttggc catcgcctta gatgcaatcg gcggtttctc
     3361 agtagcagcg gttattccac aacatgactt gtctctcagt gctggtgtaa tccaaacatt
     3421 tgaaacgctt attttacatt ttaacagtca tttacattgg ttggtaaaag tgattgctct
     3481 catgattgcc tgtggcgtta tgggtgaagt tagttcttgg gtagttggtc catcacgagg
     3541 gatgtttgca gctgctcagc gaggtctgtt accagttttc ttccggaaaa ctaataaaca
     3601 agacgttcca gttccgttga ttatgataca aggaattatc gttactattt gggcagcagt
     3661 cttaactttt ggtggaggag gcaacaattt atcattctta gtagcaatct ccttaactgt
     3721 tgtcatttat ctcgtaggat atttactatt tttcctaggt tactttgtat tagtttttaa
     3781 gaaaaaagac ttaaaacgaa cttacaatgt accaggaaaa actgttggca aaacgattat
     3841 cggtggaatt ggttttattt tatcagtgtt cgcattgctt atctcttttg taccaccagc
     3901 ttcaattgca gctagtgagc accgaacata ccaaatcata ctacttatta gctttgtagt
     3961 gactgttctt ttacctttta tcatttatga agtacatgat aaaagtgctc acacaactat
     4021 tgaggaacct actcacgtga aagctgaaga cgttaatccc gctgtttatc cagctgctag
     4081 aggagagcac cacgttacaa aaaatgatga acatatttta aaacattagg aggaattcat
     4141 tatgttatac ggaaaagata atcaagaaga aaaaaactat ttggaaccaa tttttggctc
     4201 tgcaagtgag gatgttgact tgcctaaata taagttaaac aaagaatcca ttgaaccacg
     4261 aattgcttat caattagtac aagacgagat gttggatgaa ggaaatgcgc gattaaactt
     4321 agctactttt tgtcaaacgt atatggaacc tgaagcagtg aaattgatga cccaaacgtt
     4381 agaaaaaaat gcaattgata aatcagaata cccacgaaca acggaaattg aaaaccgctg
     4441 tgtaaatatg attgctgatt tatggcatgc tccaaataat gaaaaattca tgggaacttc
     4501 aacgatcggc tcttcagaag cctgcatgct gggtggtatg gccatgaaat ttgcttggcg
     4561 taaacgtgct gaaaaattag gtcttgatat tcaagcaaaa aaacctaacc tggtgatctc
     4621 ttctggttac caagtttgtt gggaaaaatt ctgtgtatat tgggatgtgg aactgagaga
     4681 agtcccaatg gatgaaaaac atatgtcaat taatctagat actgtcatgg attatgtgga
     4741 tgagtacaca attggtattg taggtattat gggtattact tacactggtc gttatgatga
     4801 tatcaagggt ctgaatgatt tagttgaagc tcacaataaa caaactgact ataaagtata
     4861 cattcatgtt gacgctgcat cgggtggctt ttatgcacca tttactgaac ctgatctagt
     4921 ttgggatttt caattgaaaa atgttatctc aattaattct tcaggtcaca aatatggttt
     4981 ggtatatcca ggtgtgggtt gggtcttatg gcgtgaccaa caatacttac cagaagaatt
     5041 agtatttaaa gttagttact taggtggaga aatgccaact atggctatca acttctctca
     5101 tagtgcagca caactaattg ggcaatacta caactttgta cgctatggct ttgatggtta
     5161 tcgtgatatt caccaaagaa ctcatgatgt tgctgtttat ttagccaaag agatcgaaaa
     5221 aactggtatt tttgaaatca ttaatgatgg atcagaattg ccagttgtgt gctataagct
     5281 gaaagaagat cccaatcgcg aatggacact atatgattta tctgatcgtc tgttaatgaa
     5341 gggatggcaa gtcccagcct acccattacc taaagacttg gatcaattaa ttattcaacg
     5401 cttagttgtt cgagcagact ttggaatgaa catggctggt gattatgtac aagatatgaa
     5461 ccaagcaatt gaagagttga ataaagctca tattgtttat cataaaaaac aggatgtgaa
     5521 aacgtacggc tttactcact aaaattcttc agagaaatat aaaagaagtt aattaactaa
     5581 taaaaggagt tgtgattacc acacagctcc ttaaatctat ttgaataaat atatgatatt
     5641 catttgttac actctcaatc ttagctgttg ttctattcat cattactctt attgtaagta
     5701 gttcagtcaa atttgcttgt tcaattgatc gataacagta tgaattgttt gaaaagtaat
     5761 cggatatata attgttttct cactacctaa gccttcttgg tataaagaac tatcgcaaag
     5821 tataatccgc tgagtacaaa agaaagtgtc gtctactatt tctctaagtt gtttacaaat
     5881 gatattacta atagaaaagt gttctcccaa aatgtcttct aactgttgtc gatagtataa
     5941 atacctaaag tctgacggag ctactatgaa cacttcaatt ggagatttcc gtttatgctc
     6001 atttaaaaga cttaaactaa tggttagttt acgaatagaa ttctcattcc aacgcagaaa
     6061 taaattgttt tgttttcgcc attgttcaag aatttcatga acttctaagt acaaagcgcg
     6121 ttgctcttca tttaacaagt aagtcttatc aggttgaaat atctgaatat cagcccaaag
     6181 tgagcggata aacgggagaa gtgctttatc aaaaagtatc tgattttctt cagatatatt
     6241 cagagataag ataagttttt gactgagctc aatcaccaaa gggttatctg ctacatggtt
     6301 ttgataaaca acgttcaagt ctttttgtaa caattcaaag ttatcgcata gataatttct
     6361 agagttgaat agaaagtaga tataaaggca ttcatcttcg tcatgacata aagagaaaga
     6421 aagttgctct aatcctttct gtattagctg aaacaaggga gtatgtcggg caactctttt
     6481 ttcttcctga ctaaaatata ttgggttagt cttagatctc tgcaaaccga tagcgatacc
     6541 taataaaata aattgttttt caactgtagg gtaacttctt gaaaaaaatg tttttctaca
     6601 taatcaatca attgttgacc gctttgaata attgatttat ttagctggat caactctgtc
     6661 cgatttgtct catagattat cgttagtaac aaacttcgat aatccttttc aggaatttca
     6721 aaatggccat cagcatttaa gtactgcatt tgtttaaaaa aattaatcaa ctcatttcgt
     6781 aagttgtaaa ctttgcttaa cgaaatgaag gtagtatcag ctatattact ccaattgtgt
     6841 tcccctgata aataatgtcc tagtacattg aaaaagtcag agcgctgata gatgagttga
     6901 gtgagtgcca acctcgaaaa cgaagagtcg aatgcgactg taaagctact tctagatttc
     6961 tccactgaaa taatttgctg atggagtatg tcggtaatgc attccaagtc gttagtgaca
     7021 gtgagtgggc aaacgttcaa ttgatctgct atttcgcgaa tctgaatggt ccctttttcg
     7081 tgtaattgct cacaaatgta aacttgacga aaaatacttt tctccagata ggtttccaac
     7141 atagtactcc tcctagtcat tttatacata actattataa ctctaccaat cggaatagtc
     7201 ctgtaatata ttgaatcaaa aatataaatt ataaaataat tagatggggt atttggttta
     7261 agtatccctt atatagtaat aaatttatag gtgtgattct cgaattaata cccgaaaatg
     7321 tgagagaatt tttatggatt ttttaggata caaattaatt atttttgctt ttatcctgat
     7381 taccagtcca gtactgtcgg tatcccattt tgcagcaaaa tcatgttgat aaagtgacaa
     7441 gaagactgat gagatatatt atccaaattg agaagataat taatcggatt cttgagtata
     7501 ccctactttt taagaaagta gggtatacaa gcgtatgaat aaagacataa ctttccctgt
     7561 gatggacgtt cggcttgttc caattaccaa aatacaggcg aacgattata atcccaatcg
     7621 agtagcgtct ccggaaatga acttattgga gctttctatc attgaagatg gctttactca
     7681 accattagtt tgttattaca aggaaaaaga agagaagtat atcttggttg atgtgcttca
     7741 taggtatcgt gttgctaagg aaagactcaa cttaaaagtt gtaccggtaa cagttattga
     7801 taaacccata gaagaacgta tggcttcaac aattcgacac aatcgtgcaa gagggaccca
     7861 tgaaataaga ggaatggaaa ttgtcatcca aagattagta aaaaatggat ggtcagacaa
     7921 gagaatatcc aaagaattag gcatggacat tgaagaaatt tttcgcttta agcaagtgtc
     7981 tggtggaatg gcaacagttt ttttgacaaa ttttataagg tgcagaactt ctttccgtat
     8041 gctattccga ttgtccttga caatgagcct cctcggatgt gacgatcttc ggcaggagct
     8101 aacagttaaa gttagactgc ctcgctagcg ttagcacatc cgagctcatt atcaaggatt
     8161 cgctgcgcca atctctggtt acggtaacca accggtgtct cgtagccaag tgtaccgtgc
     8221 aaccgaaggt ggttccacca atttacatag tcaaataact ccaaatccaa ttgttgtaag
     8281 gtttcaaatg tgtattgata gacaaattct actttcaacg acttataagt tgattcagct
     8341 acggcattat caaaaggaca gcctttatga ctcaatgatc gattgatgtc aaaagttgtt
     8401 aataattcat caatagcttg gttatcaaac tcttttccac gatcagtatg aaaaatctca
     8461 acctctgtca gaggttgttt gatacggcta aatg
//
LOCUS       DADVXK010000107         8307 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.108, whole genome shotgun sequence.
ACCESSION   DADVXK010000107 DADVXK010000000
VERSION     DADVXK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.108"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            624..1487
                     /locus_tag="KB909_002411"
     CDS             624..1487
                     /locus_tag="KB909_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6838377.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1616..3238)
                     /locus_tag="KB909_002412"
     CDS             complement(1616..3238)
                     /locus_tag="KB909_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838378.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3487..4008
                     /locus_tag="KB909_002413"
     CDS             3487..4008
                     /locus_tag="KB909_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6838379.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4194..5924)
                     /gene="spxB"
                     /locus_tag="KB909_002414"
     CDS             complement(4194..5924)
                     /gene="spxB"
                     /locus_tag="KB909_002414"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBB6838380.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            6089..6907
                     /locus_tag="KB909_002415"
     CDS             6089..6907
                     /locus_tag="KB909_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBB6838381.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(7010..7207)
                     /locus_tag="KB909_002416"
     CDS             complement(7010..7207)
                     /locus_tag="KB909_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838382.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7376..7954
                     /locus_tag="KB909_002417"
     CDS             7376..7954
                     /locus_tag="KB909_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6838383.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            8049..8186
                     /locus_tag="KB909_002418"
     CDS             8049..8186
                     /locus_tag="KB909_002418"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838384.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2481 a         1510 c         1636 g         2680 t
ORIGIN      
        1 aaaccgtgtc acagtccctt tttccgaaca aacggtgttc aaaagcttgc atctacggca
       61 ctaagcccaa tcagatgaaa aatatggagt gctattttta tctgattgtt cttactgctt
      121 gatgcagagc agctttttca caacctctcc actaaacggt gttctcctgc caactcctcg
      181 gtcacaagtc acaatattca acaaacatga gaagctgttt tttgaaattg ttccttgtga
      241 ctcggagcta aacggcaggc tcacaacctc ttggtaaacg gtgttcaatc agctgaccct
      301 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttttccgttt ttttctctaa
      361 tactcaggtc aaaacgctga tttcacaacc tctgattcac ggtgttccag aagtagcttc
      421 tacggaaata agccgaaatt tcacaaaaat ttgagaagca attttcgtaa attccttctt
      481 atttcttgaa gctgaccact tctgtcacaa cctcttattt tgattagaac ttgcgaaaat
      541 aaaccggtta aagtgtgtct agcgcaagag atttgctata atagacgata agggtaaaat
      601 gtaacgagaa ggggttgaaa aatgtgtatc aaattgtaac agattcttgt tgtgatctgc
      661 cataccatgt attagcaaaa gaaaaagttg attttttatc aatgaatctc caattgaatg
      721 atcaagagtt agtagatgac ctcggaaaga cattcaatta tgaccgctac atgaatcagc
      781 tgaaaaatgg tgcgatgcct acgacatcac aaatcaatgt tggccgatat ttagaatttt
      841 tccgttctta tgcggaaaaa cagattcctg ttttatatgt ggctttttcc agtggattaa
      901 gcggctctta cagtagtgcg cttcaagcgg ttgaattgct gaaggaagaa tatgaagacc
      961 ctgagatcta tgtttttgat acaaaagctg caagtattgg ggaagggctt ttagtattgg
     1021 aagctgtaag attgaaaaaa gaaggtaaaa gcatcgaaga aaccctagag tggctggaaa
     1081 gtaattattt gaaagtccat tcatgggtaa cagtagacga tctgaaatat ctagaacgag
     1141 gcggtaggat ttccaaagca agtgctactc ttggcagtct attgagtgta aagcctatta
     1201 ttacggtgga taaagaagga aggctgacga atgttgacaa agttcgagga agaaacaagt
     1261 cgatccagac aatcgtcaat gagacggtaa aaacaatcgt tgcaccactt gatcaaatcg
     1321 tttatgtggc ttacgctggg gatctagaga gcgcggagaa ggcaaaacgg cttttggaag
     1381 agcagataaa gatgaaagat gtgaagcttt atcccttagg accaacgatc gccagtcaca
     1441 caggctatgg ctgtatcgcg attttttcga tgggaatcag tcgataaaag cagtaactca
     1501 ttctgtaaaa aagcccagaa attgattgta acaaaaacag cgactcttaa aagatagatg
     1561 agcatcctat ctcttagagg tcgctgtttt tttatttttt aagctaaata ggccattatg
     1621 cccataactc gttcaattgt ttttgaatat ctgcattttc caaaaattca tcatatgtcg
     1681 tatcagctcg atcgatcaca cctttatccg aaacggcaat gatgcggttt gccaatgttt
     1741 ggataaattg atggtcatgt gacgcaaata agattgagcc agtaaatgcc atcaagccgt
     1801 cattcaatgc tgtgattgat tctaagtcta aatggttcgt tggatcatct aatacaagta
     1861 cgttagcttt cgaaagcatc atttttgaaa gcatgcaacg gactttctct ccaccagata
     1921 aaacattcac tggtttcaat acttcttcac cagaaaacaa cattcttcct aagaagcttc
     1981 ttaagaaggt gttatcatct tcttctttac ttgcatattg acgcaaccag tctaaaatcg
     2041 ttagatcagt atcgaattct ttcgttgtat cctttggtaa ataagaatta cttgttgtca
     2101 caccccaacg tactgttcca gtatctggcg taatttcacc catgataact ttgaatagcg
     2161 ttgttgttgt tatatcattt tctgcgacga aagcgacctt gtcttctttg ctcaaattaa
     2221 aagatatatc atctaaaatt ttctttccat caatcgttac acttacattt tctacctgca
     2281 ataagtcgtt tccaatctca cgttcaggtt tgaatccaac gaatggataa cgtctagaag
     2341 aaggttggat atcgtctaaa gtaatttttt caagcatttt tttacgtgaa gttgcttgtt
     2401 ttgattttga tgcattcgca ctaaagcggg caataaattc ttggagttct ttgatttgtt
     2461 cttctttttt ggcatttgcg tttgcttgaa gtttagccgc tagttgacta gattccaacc
     2521 aaaaatcata atttcctaca taaagtttga ttttaccaaa atctagatcc gccatatgtg
     2581 tacatacttt gttcaaaaag tgacggtcat gggatacaac gatcacagta ttttcaaaat
     2641 tgatcaaaaa ttcttccagc caattgatcg attggatatc cagaccgttt gttggttcgt
     2701 ctagcaaaag aacatcaggt ttaccaaata gtgtttgtgc taataacact tttacctttt
     2761 gtccaccagt taattcactc atttgctgat ggtgcaattc ttcagggatg ttcagacctt
     2821 gcagtaaaac agctgcttct ggttcagctt cccatccatt aagctcagca aattctcctt
     2881 ctaattcagc tgctcgaata ccatcttcgt cagtgaaatc ctctttcatg taaatcgcat
     2941 ctttttcttt cagcacttca tacagacgct tgtgtcccat gatgactgtt tcaagtacag
     3001 tatagtcttc atagtcgtaa tggttctgtt tcaatacggc catccgttca tctggtccca
     3061 tagtaacgga acctgtggaa ggctgcagat cccctgataa cactttaagg aacgttgatt
     3121 tacctgcacc atttgcacca atcaagccat agcagtttcc gggggtaaat ttaatattca
     3181 catcatcaaa tagtttgcgg tctgaaaagt gcaaactcac atcatttaca gtaatcaatt
     3241 tttttcctca cttttatcat tattagtttt gacaagtctt atagaattat ataggggaaa
     3301 ggtaaaagat tcaaggcaat cgaacattct ttgtgtttca cgtgaaacag aatgaaaaaa
     3361 ataaaaataa aagcggagcg aaaatagcta ctataggatt tattagtttg caacagcata
     3421 atttttgacg ttatttataa gagggagtac tataaaactg taaaagaaat gaaagaagga
     3481 ttgaaaatgg atgaaaaaag aaccatcgac tggggctcat tgattttggg aattttattt
     3541 gtacttgtct cattgttatc atttcaagac cctgtcggaa atttagttgc aattgtagta
     3601 gtctttgcga tttttgcctt tattaaaggg atatttgaac tgtttgtacg gaacagatta
     3661 aaagagctaa caggatataa aggaaagatg cccttaataa tcgggatcat cgatattcta
     3721 gttggcgtct ttttcttatt caatattggt gcaggagtcg cagcattgcc ttttgttttt
     3781 gcagtatggt ttattgctga ttcagtttta gcgttattta ctgctgactt ggcaagagga
     3841 gtaagtgaag gatattattg gtttacgatc atcgtcaata ttttaggaat tttattagga
     3901 attttcttat tgtttaatcc aatttcttct gcgttgacat taagcttttt agttggattc
     3961 tattttatgt tatttggtat cacacatatc gtctatgcat ttagataagt aaaatcaaac
     4021 aaataaaaaa gccggcttcc gattacagtt ttactgttgt aattggaagc cggctttttt
     4081 atcatggaca aatatgcacg aggtgatttt taggtgtcga gacaaattta tgcaaaaatg
     4141 tgagaagcta tatacacaaa ttttatctta atactcgaag catagcgcag ttgtcacaac
     4201 ctcttttcat ataattcatt caatactggc aaatcatgga cttcatattt ttctttgaat
     4261 gcttggattt cttcttcaga atattttctt ggatctaaat gcagatcttc tactggcaat
     4321 gggcgcttgt tattgatctt cacatcgatt actacaggac gatctgattt tgcagctgca
     4381 tcaaaggcaa atcgaagttg cgagtattct gtgactgtaa agctatttgc cccgagcgct
     4441 tctccaactt taccgaaatc tgcatcttct aaaaatacac caaatttctt ttgttccgta
     4501 tcttcttgtt ctgcttcgat gaaaccaaaa gaatcattcg aaaagacaac attaataatt
     4561 ggaagctgat atttgacttg tgtaatgata tcttgcatga ccatagcaaa cccgccatca
     4621 ccacttaagg taaatacttg tttttctggg tagcttagtt gtgcggcaat tcctcctggc
     4681 acaccattac ccatagttgc gaaccatcca gatgtcgtat gtttttgttt accgttcata
     4741 ttcaataaac gaatagaatg gatagtcgtg ttaccgacat ctgtgacgaa aatcgcatcg
     4801 tcttcagcaa tacgattgat ttctttatag acagcctctg gacgaatcgg ttcttcctct
     4861 cgatcttcaa aagatttcaa ccaatttacc catttttctt tattttcttg atttgctagg
     4921 taccagctat cagcagggcg agcatcccct aactcgacaa gtctttgcaa agctgtgttt
     4981 gcatcaccga ggatcgacaa agatgtttca tggcgtcgtc caaattttga cgcatcgata
     5041 tcgatttgga taaattcagc agttggatta aaaaatgcac gtccaaatgg gaagtcgcta
     5101 ccgacaaata agatcagatc ggcttctgcc aatgcttcat ttccgggttt agtagcgaca
     5161 cgtccagcaa aaccaagaaa gttttcataa tcatcaggaa taattccttt tgctagaacg
     5221 gaagcgacaa caggaactga aaaatgttct gagaattctt tgatttgcgg aaatccgttt
     5281 cgcgttcctt gaccaacata aagaactggt ttttttgctt tttcaagata aggcaaagca
     5341 gctagcaaat ctttttcttc tggtaatatc acacttgttt tgtgagtgtg agcggtggag
     5401 aaaggttgtt cgtcaatttc ttcaaaacca agatcaacag ggatagtcac gatagccacg
     5461 cctttatgct cataggcggc tttaatggct tcatctacta catgcggaag actttgtggt
     5521 gtcatgactg tacgattgta tacgctaaca tctgcgaaaa taggattttc atttagttcc
     5581 tggaaagagt tatagttcat ggatgtagaa gcaacttgtc ctaagaacgc tactagaggc
     5641 acatggtcca tctgtgcatc atacaaacca ttgatcaaat gtgtcgcacc aggtcctgca
     5701 gagccgaaga cagcgccgac tttccccgtt aattttgcat ctgcagcggc tgcgagtgcg
     5761 ccgacttctt catgacgaac ttgaatgtag ttgatttcgg ttttttcttg atatagcgca
     5821 tccataattg aattgaaaga tcctccggga atgccgtaaa tatggtcgat accccagctt
     5881 tcaagaactt ttaccattgc gattcctgca ttgatttttg acatggtgtt tcactccttt
     5941 agcaatgatg atacataaat tttttgtatc tagagtatag aactttttat cgaaaatccc
     6001 aactaattcg tcttttcaca aaaatgtagt catgtttttg ggaatatgct agagtagtac
     6061 atagatagat tcaagagagg ggaatggcat ggttgaatgg ctattgagac ttgaaccttg
     6121 gcagcaagca cttgctggga cagcttttac ttattttatg acagctcttg gtgccgggtt
     6181 ggtttttttc tttaaagaaa tcaaaaaaga agtgctaaac ttgatgttag gatttgcttc
     6241 tggtgtcatg attgctgcaa gtttttggtc tttgttagat ccggctatta caaaagcaga
     6301 agaaaatgga gatattgctt ggctagttgt aagtattggg tttggtttag gcggtgtgtt
     6361 tttatatatg gcagataaaa cactgcccca tatgcatttt ggaccacaac atgaagcaga
     6421 aggattgcct acccatttaa aacggacgat cttgcttgtt ttttctatta cattgcataa
     6481 cattcctgaa ggtttagccg tgggggtagc attcggtgca gcagcaactg cggataatcc
     6541 gacagccgct atattagccg ctgtttcggt ggcgctaggt attggtatcc aaaacttccc
     6601 agaaggagca gctgtatcaa tcccgttgcg acaagaaggt ctgagtcgta aaaaggcctt
     6661 tgtttacgga caagcttctg gaatcgttga accaattgct ggagtgattg gagcgctact
     6721 agtaacgaaa gtggagctgc tgcttcctta tgcacttgct tttgccgcag gagcaatgat
     6781 ttatgtcgtg gtggaagaat tgatccctga agcacagcag acattgtcca gcaaacgtca
     6841 ttttgcagtt tttggcgtca tgagtggatt tatcattatg atgattttgg atgtggcatt
     6901 aggataaata aaaaaaatat atatgatata tcaaataggg ccgcgaactt atatcgcgac
     6961 cctatttttt tagtaagtta tatcataatg aagtgaatgg tatcatacat taataatagt
     7021 tttttctatg tgtatttcct ttgatccagc gaacaagcca gatgataagt gcgattggga
     7081 ttagaacttt gaccgcaaac cataaaagcc cgcttaggac actgacaaaa agactgatga
     7141 cgaagctagc tgcaattagc actaaaagaa ccatgaagat atttaagaac atattttttt
     7201 gacgcataca aaaccctcct cttgttcatt ctttactata gaaaaagtat aacagggatt
     7261 gtttaaaaac acctccaact gaagactgat ttttacttca tctacttaaa tgatcaaaca
     7321 attgcttttt ctctggttta tcatctaaaa tagagcggaa aaggaggaga atatcatgcc
     7381 taaaaatcgt cttgaagcat ttacagatgc tgtaatcgcg attatcatga ctattttagt
     7441 tttagaactt catgaaccta acggagacac gtgggaggcg ctcgctgcat taggttaccg
     7501 attttttatc tatattgtca gttttatcat tttagcgatt tattggaaca atcatcatca
     7561 tttatttcaa gttgtacata agataaatgg acgggtctta tgggcgaaca gtttctttgt
     7621 ttttgcgctt tcgctttttc cgtttgcaac ttcatggatc agtgagtaca tcaatagcct
     7681 ggctccagaa atgacttatg gttttgttac cttgaccgct aatattgcgt attatatctt
     7741 ggcaaaagaa cttgtcaaag caaataaagg ccacgagaaa gcattgaagg cgatgttgaa
     7801 taattacaag aaatcgtatc tatcgattgg tttgaatgtg ttaggaattg tcttagggta
     7861 tttagtagcg ccagtagccg tgctgatcgc aaacatcgtg attctagctg cttggatcat
     7921 cccaagtcgt accatcgaat cacaatatcg gtaaaatgat ccgtgtttaa aatttaagag
     7981 aaaaatatag aaaaaataaa taaacgatca aatatccgag tgatactagt attcaaagag
     8041 ggatgcagat ggatcaaaaa agaattcatg taggactgat tactagtttt gtcacgatgc
     8101 ttatttattt ggatcaaggt catttgactt ggacagtagt tggtgtcgta ggatttttga
     8161 cattattcac agcaataaaa aaataaacat ctttatgtaa tctgatgttc tatctattta
     8221 agaaaagcat gtttacagca gtatgattct gttgtaaacg tgtttttatt tgtggaaaat
     8281 ttaattttta gaaaagtgta tcgaaaa
//
LOCUS       DADVXK010000108         8296 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.109, whole genome shotgun sequence.
ACCESSION   DADVXK010000108 DADVXK010000000
VERSION     DADVXK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.109"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            14..1141
                     /locus_tag="KB909_002419"
     CDS             14..1141
                     /locus_tag="KB909_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6838385.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1359..2501)
                     /locus_tag="KB909_002420"
     CDS             complement(1359..2501)
                     /locus_tag="KB909_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838386.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2506..2691)
                     /locus_tag="KB909_002421"
     CDS             complement(2506..2691)
                     /locus_tag="KB909_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6838387.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3045..3290)
                     /locus_tag="KB909_002422"
     CDS             complement(3045..3290)
                     /locus_tag="KB909_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838388.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3284..3685)
                     /locus_tag="KB909_002423"
     CDS             complement(3284..3685)
                     /locus_tag="KB909_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6838389.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="KB909_002424"
     CDS             complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="KB909_002424"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBB6838390.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5703..7469)
                     /locus_tag="KB909_002425"
     CDS             complement(5703..7469)
                     /locus_tag="KB909_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBB6838391.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7482..8276)
                     /locus_tag="KB909_002426"
     CDS             complement(7482..8276)
                     /locus_tag="KB909_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6838392.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
BASE COUNT         2656 a         1590 c         1117 g         2933 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aataaaaata
     1321 ggctatgaca gcagcgtgac agcaaaaaag atggaaagtt aaatatcaaa cctcgtaatt
     1381 tcatttgcga gtgcttgatt tgtttctgga tataagtgtc catatttgtc caaagtagtt
     1441 ttaatagagg catgacctag acgcttagat attgcataga tatttttatt atgttcaatt
     1501 aaaaaggcaa catgcgagtg tcttaatcca tgcatatgaa ttggttttac tcctgcaatt
     1561 tcagctagtt tttttattct gcttaaaata gttcttggag atggcggtaa tccatcaaaa
     1621 gaaaaaacca attctatatt tttcccaatt gattgttgag tttttttcca tgtttttaaa
     1681 tcttcaacgg tttgtctgtc taacgaaatt atccgaatac ttgatgtatt ttttgtttca
     1741 gcaaattcat aatcttgtct tgtacggatg taaattgact tatttacgct acatctgcca
     1801 tttattaagt caaagtcttt ccattgtaac gctaagagct cctcactcct tacacctgta
     1861 acaaaaataa aacgcatcaa acgtttataa aattcttcat aaaaatcccc gtgataaaca
     1921 ctattatata ctttcttaaa ttcatcaact gtccaaaatt ctacttgagg acgctgagtt
     1981 tttattttac ctatagtatc tacaggattt tcttcaataa tttcaagtac aattgccctt
     2041 ttaaaaacta ctctcaactt attgaatatc tgtttaatat aatttggtga taatggttgc
     2101 tcaatgccct tttttacaac atggattttc gataaaaact gttgaaattc ctgtatatga
     2161 attggtcgaa tctttacaac ctgcatttct ccaaaaaaat ccaatgcacg ttgtaaaata
     2221 tgatctgttt tcatatatgt tttttctaca gttcccaact tataccaagg aaaaaaatac
     2281 tctcgataaa aatcatgaaa cgttattcct tgcagataaa ttccttgtga atcagaaaaa
     2341 ctttgtttta actcttcgag tccccttcta gcttctcctt gagttttgaa gcctcttctg
     2401 gtcacttgaa ttctttttcc aaagcgatct tgtcctaaag ttgcagaaaa aaaccaagtg
     2461 cctctttttc tgtctttata aacattcgca attttcctca ttttactatt cctcccaaga
     2521 aatatggaga acttcttcta aaattgaaat aggaattctt tttatttttg aattacgata
     2581 aaaaaagtat cctttctcaa ctaaaagttc tttacattcc ttgaagattt tattagcata
     2641 gtactgagaa aaacctagat taatcaaatc ttttcgagta gctgttttca ttatagcacc
     2701 ttccttactt tttttcattt atttctatca gctgcttttg tcaaaagcac ataggaattt
     2761 cacctctccc caagtttacg gcgagcctta cggaagtatc attatcccaa ctttaaatca
     2821 tcgcttttta ttgactataa aaattatttt agaatattta tcgctccttc tttacagcaa
     2881 gaaatcatgg cgcaactaaa atatgctcct taaagtgtta acgtactgat agaatctatt
     2941 taattttcaa tgaacaatag gttttctacc taaaagaatc tactaattcc ttaactatta
     3001 gaagattctt ttaaacagaa aaagtggaaa ggggattttt ttaattagtt aattttaaat
     3061 tttaagatcg cttctattaa tttaatttct agctgactta tcatatattc atctacatag
     3121 gtaacgaatt gacctacctc gttaaatcca tttgtcaaac ataacttagc catataagaa
     3181 tgataatgtt tgagtatcat cttgatcgaa attggatctc cttctagagc agataagata
     3241 atggatagtg gaactaatag gtactgccgc tttttagatt tatctaccat aggtcatacc
     3301 ccattttcaa ttgttcaact gccttctttc gttgatacca gataccactt gtgctcatat
     3361 tgagaatttt accgatttca gcatcattaa aacctgcaaa ataataaagt aggataatct
     3421 ttcttcttat ctccgataac tgatcaattg ctgctgataa cttttgatct gaaattaata
     3481 tttccattcc aaataagaaa tagacatctt gttcatcaaa atgagtttgg gaatacctgc
     3541 cttcatttga atctgccaat ggttcctcat tatcctttat gttagcgttt cgttttcgaa
     3601 tagacttagc ttcgtttcgt aatacttttt tacagtaggc atcaaattgg tgttgtatag
     3661 atatgtcatt gtaatgttgt tgcatgataa tatgctcctt tttccccctt tccactaata
     3721 caacaatcag aaagcccctt tttttcgaaa aaactagaaa aaaaacataa aaatatttat
     3781 cattctttaa acagaaaatc tttctataaa aaacaaaaaa aaacgattag gctaggctaa
     3841 tcgttttttg aacattctta aaaaatccaa attatttttt ataactgaaa ttgggtattg
     3901 atgaccatcg tttctgtaga tagtaagcaa tcattttagg ttttctatct ctagtaaaga
     3961 ttcctttctt atttccttgc actcttaaaa tcccttgact tgttgcaaaa tctgcaaaat
     4021 tccacacttg ttcaccaaca aaattttcac atgtatctat tacttcgtga tttgcttcgt
     4081 aataagccac ttgatactct tctgtaaaca ttgttggtac tgtatcatga aatccagcta
     4141 ctgtatctgc tccatattct gtaaacatta ttggcgtatc aggacatctt tccatccatc
     4201 catctagctc ttttttcaac agatattttg catgtgccag atcccctccc gaaacatacc
     4261 aaccataata acgatttaaa cataaaacat cgacaatatc tcctacctta caaacatctg
     4321 gcgttgattt tagataagta acgattgtta caggtctttt ctgcggatca agttctttag
     4381 ttaattcaac taaaggttca aaatattctt tagcaccttc ggaatccgaa tctggttcat
     4441 ttgcaataga ccacattaca acacttgggt ggttcttgtc gcgttctatc aattccttga
     4501 tcaccgtttt atgagaattt tctgttcgta tctctttcca cgtattatgt ttttccacat
     4561 tatcatctaa taaagtggcc atgaaattta aatgtaaccc tactgcaggt acttcatcaa
     4621 taactacaat accttctcga tctgctaatc gcataatttc ttctgagtaa ggataatgtg
     4681 atgttctaaa agaattagca cctatccatt tcattaaatt aaaatcttta atatttacag
     4741 cctcattcaa accacgtcca ttaacatacg aatcctcatg cttaccaaat cctttaaaat
     4801 aaaaaggttt attattaatc aaaaatttgc cattggtaac ctgaacactg cgaataccaa
     4861 attcttctgt ataggtatcg atcactttat tatcatcaat taaactaatt ttcatactat
     4921 ataaataagc gtctagaggt tcccaaaaaa ttggattctt aagctgaatc attcctttct
     4981 ttccttcagc ttcagctaca agttgagcct cttcgtcata tatcgctatt aagatttttc
     5041 cggtccattc tgtatcgata ttgaattcta cacttgcatc caaatcagtt attcttgtat
     5101 taatagtaat atcacttata tagtctttcg gagttgtata taacttaaca ggtctatgaa
     5161 tacctgcata attgaagaaa tcaaaattaa ctaagttttc cttttttata tccccatttt
     5221 cctgtactgt ttccttcata atccccacag gtaaagtact atcgtcaata atattgttta
     5281 cagcaactgt aattcgatta ttcccgtctt ttacaaaccg attaatttca gactcaaatg
     5341 gtgtaaaccc acctttgtgt tgagtaataa actttccatt caaaaaaact tttgcttcat
     5401 gtgttgcaga tccaaaacga agaactaatc tttcttctaa taatctttta ggaagagtca
     5461 cttctttttc ataccacacc catccaacat gatttctaat gttctctgtt tcaaataaat
     5521 cattataaga agagggaact gaaatcggat aactctcttt ttcatttatt ggttctaaag
     5581 caagttcttc ctgtaagtca tcatttgtat ctaatttaaa tctccagaga ccgcttaagt
     5641 caattacttg cctcgtctct gtcataatgg gatacaacat ataaaccact cctatctaaa
     5701 tattaaataa atgtatcctt taaaccacaa taagcatcta ttggacttac tcccttaaat
     5761 tcagaaagac ccattagttt gtccaccaat atttctaaag tttcttgttt tccatcataa
     5821 gtattaatat aagtctttac ttgaggtaca tcagccaaat gaaacggaca ctgtacagat
     5881 acaaaaattg ttggaatttc atgaatgtaa aacggtatat ccggagttcc tttacttgct
     5941 ggccagacaa ttcgttgaac tgtgcctgga ttaacattag ctatattaat gatcaagtca
     6001 tattttttag ttaaattttt aattggtctc ttagcagcat atattccagc tatattttta
     6061 attttttctt cttgcgataa tcctttcaat tcttcttcag gtgaaatgta tttttcaact
     6121 tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa tggcttgagg tctatttcca
     6181 gcaactactt caccaaaccc accttttacc ccatgtacat ctactagtaa aatcctttta
     6241 tatttttctg gtacaatagg ccaaatatct tgtttatctt taactaatgt aattgcttgg
     6301 tcagccacct ctttaaaaat tgatttattt tcaattaaac caattttttc cagagcttct
     6361 tgcttaggta ataaaatttg ttcttttgct tttttgtgta atcccaattt agcttttaac
     6421 cctaaaattc tttttaaggc atctaataac cgatcatcag tgataattcc tttacgatag
     6481 ccttccatca tataattaaa gtcttcatct ggatcattaa aaaatagaaa tagatcacat
     6541 ccagctgcaa tagaagtggg caataattct gatcgtttca ttgccccagt cattcctaac
     6601 atatgactag catcagtaac tactaatcca ttaaatccga gttttcctct aagtaagtca
     6661 gtgattaatt cttttgataa agttgcagga agtaaatctt catctttcag atcaggatta
     6721 aaatgttttg aataagctgg catatggata tgacctgcca taattgaagg taatccagct
     6781 tctattaagc ctgagtatac ttttccaaaa gaattatccc attcttccgt acctaaacta
     6841 ttaatactaa aagatagatg ctgatctcgt tcgtcaatac cgtcaccagg gaaatgttta
     6901 gctgcaggca aaattccact ctcctgaata cctttcatat aagctaaact aagttctaaa
     6961 actttatcag ggttttgtcc aaaagatcga ctagaaatga taggatttct ccaatttcta
     7021 ttaatatcta caataggagc aaaactccag ttacatccaa tagccgatgc ttcaatccca
     7081 gaaactctcc ctaattcata agcatatttc gcatcatttg ttgcaccaat ttttacttct
     7141 acaccaactt cagtaccatc tgtacaagct ccgttaccac ctgcttccgt attagcagca
     7201 attaatagag gaattttact ttctgtttgt aagatatagt tttgatcata tacctcatca
     7261 gcagttcctg gattatatcg tacagctcca atatggtact gattgaccat attactcaag
     7321 taatttttat cacgactaga tcccatatta acaaacaatt gacctatttt ttcttccaaa
     7381 gtcatagaat caatcgtctc ttcaatccaa gaaatagcat cttcatctaa attatatggt
     7441 ttttttcgta aatctacttt tatagtcatt ttctttctcc tctacttatt agtaagattt
     7501 ttccaaaaag tatctatata tttttgttca atatctacat aatctcccga taaacattta
     7561 aataaaacat cagttcttaa gttttcccat gattcttttt ctttattgac caaaatagga
     7621 taaaagaaaa ctttattttt atttgcagct tctagatcac caggagaatc accaatcatt
     7681 aatatcttat ccaaatcaca accattttca attacacttc gaataatatc ttcttttttt
     7741 cctttatctt gacaacacag ttcatcaact aatgataata attcatgtct ttcccattct
     7801 tcttgaacag cttccttatt agctgagctt acaataatta tcttcccata ttttttcaga
     7861 gcttttatag tatctctagc acttaaaaag ggtttatcta atccttttgc ttgactaatc
     7921 tgttgattga cttcttccga ccattttaaa gcttttaata aatcctctga ctgagaatat
     7981 tctatttccc tcttcaaaga tggattagac aattcttttg ttagagatac ccagtgcttt
     8041 aatcgattaa tcgatgttac atcatttttt tctaatgttt taactaaacc taaaaatctg
     8101 tttattccac gagtctctga atataaatta atattattcc aatcctgtag gaatttttct
     8161 ctatgatgaa catcaaaaat ctctgcagca attggtccga aaaagagatt gtgtttataa
     8221 gtcatcgtat ccataacaca gccatctgaa tcaatacaaa atatccaatt attcatattt
     8281 ctctcctatt tatgtt
//
LOCUS       DADVXK010000109         8294 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.110, whole genome shotgun sequence.
ACCESSION   DADVXK010000109 DADVXK010000000
VERSION     DADVXK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.110"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(67..654)
                     /locus_tag="KB909_002427"
     CDS             complement(67..654)
                     /locus_tag="KB909_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838393.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            829..2151
                     /locus_tag="KB909_002428"
     CDS             829..2151
                     /locus_tag="KB909_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838394.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            2306..3082
                     /locus_tag="KB909_002429"
     CDS             2306..3082
                     /locus_tag="KB909_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6838395.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            3075..3644
                     /gene="rnmV"
                     /locus_tag="KB909_002430"
     CDS             3075..3644
                     /gene="rnmV"
                     /locus_tag="KB909_002430"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBB6838396.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            3637..4521
                     /gene="rsmA"
                     /locus_tag="KB909_002431"
     CDS             3637..4521
                     /gene="rsmA"
                     /locus_tag="KB909_002431"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBB6838397.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            4972..5601
                     /locus_tag="KB909_002432"
     CDS             4972..5601
                     /locus_tag="KB909_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838398.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(5725..6834)
                     /gene="ugpC"
                     /locus_tag="KB909_002433"
     CDS             complement(5725..6834)
                     /gene="ugpC"
                     /locus_tag="KB909_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBB6838399.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            7043..7465
                     /gene="mgsA"
                     /locus_tag="KB909_002434"
     CDS             7043..7465
                     /gene="mgsA"
                     /locus_tag="KB909_002434"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBB6838400.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            7788..>8294
                     /locus_tag="KB909_002435"
     CDS             7788..>8294
                     /locus_tag="KB909_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6838401.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKI"
BASE COUNT         2610 a         1480 c         1721 g         2483 t
ORIGIN      
        1 atagataaaa aaacaatcat cggctttgac ttcgatgatt gttttcttta ttttgtaaaa
       61 atcctatcac ttgattttat ggtaaccttt tatttttgtc ttcaaacggc ttggtaagag
      121 agcagtaagc agtgcaaatg ggatcgaaaa gacataccag aaaatcgtac gtccgatacc
      181 ataatgttga tagagctttg tcaacatcac gtgtaacaag atcaacccta aaagcaagga
      241 gccagctata aaccaatgat tatcccaatg catgacttca ctaagtgcca tcactccaaa
      301 aggatagaaa taaaaataga tcccgactaa ggtcatccgc cagttctttg taaatgttcc
      361 gatattcaat aaaaagaaaa tcgctgaaag caaaataccg ataggcggaa aaagcccaac
      421 caaaaaggaa tacaacatcc cccacaagat catcacagga cctttgatca atgcaacgat
      481 tgcgatgaac aaagtcagca atattagttt ttgtgataac gttgcaacag tcattaatcc
      541 aaataaaatt aatgtgaacc aatgccaatg ggactgctgt tgttctttac gggaaaaatc
      601 gacccggttg gataaataat ctgctaattt cggataagaa cgcttaaaat ccataaactg
      661 ttcctccttc gtggaaaagg taggtttagt atacgaaaaa taaaaaagaa atacatccgt
      721 cttaagaggg agtttttcac tgaaagtgga gaaaaaagaa tggtaaatta aaatattctc
      781 agttatactg aaaattatac caaatttcaa agaagaaaga ggatgggaat gaaaggcaaa
      841 ctaaaacgag aaatcaatct gtttggcgca ttagctaccg ttatgggaac cgtgatcggt
      901 gcaggcgtct tcttcaaaac tgctgctgtt actgctagta ctcagtctac aagtttgaca
      961 ttgctagctt ggcttttggg tggtttctta acgatctgtg ctggattgac agtggctgaa
     1021 ttagctacag caatcccgga aactggtgga gctgtaaaat atattgaagc tgcgtatgga
     1081 aaattgccca gctttttatt aggatgggcg caaagcttga tttactttcc tgctaatatt
     1141 gctgcattat cgattatctt tgcgacacaa ttgacgaact tattacaatt atctaccgat
     1201 tatcttttgt tgattgcagt gatcaccgct gtttctgtga cagggttgaa tttgttaggg
     1261 acaaaagtcg gtgcttctgt acaatcagtg acgttgattg ttaaattaat accaattgct
     1321 gtgattgtca tatggggatt attgacccca ggacaaggaa ctgtccagtt atttccaatc
     1381 gaagctggaa aagatgttac ttttgtcgaa ggattgagca gtgcgttgtt agcaacgttg
     1441 tttgcttatg acggctggtt aggtgtcggt gcaatggcag gggaaatgaa acggccggaa
     1501 aaagatttgc ctaaagcaat tattcttggt ttgagttttg taacagtcgt ttatctattg
     1561 atcaattttg tttttttgaa aactttgccg attgatcatc ttgccggtaa tttgaatgca
     1621 gcttctgaag catcagacgt catttttgga ggaatcggtg gaaagctggt cactattggg
     1681 atcttgatct cggtatacgg tgcattgaac ggttatacac taactgggat ccgcgtgcct
     1741 tatgcgatgg ctttagaaga cgagctacct ttcagtaaac agctgacaaa gctttcaaag
     1801 aagtttacgg ttccttatgt tcctgcggtt ttccagttag cagtagcttg tattatgatg
     1861 agccttggtt ctttcgactt tttaacagac atgttgattt ttgtgatgtg gctattcagt
     1921 ttactgattt ttatcggtgt ctttatttta agaaaaaaag cgccggaatt gccacgtcca
     1981 tataaagtac cactttatcc aatcgttccg attattgcga ttctcggtgc tattttcatt
     2041 ttaggtatga cgatgatgac gcaaacgaaa ttagcattga tcggtatagg tgttaccttg
     2101 ataggtatcc cagtctatta tcaaaaaaag aaaaaacgct cagaagagta aaatatttca
     2161 acaacagaca gaaaaagtac gaactaggtc ctctagatct tcgtgctttt tctatttcaa
     2221 taaaacaagt tcttctattt tgatttttgc tacttctgca agtagtgctt atgtgctaaa
     2281 gtaagaatga aaaggagaga taaacatgat atttgattct catacccatt taaatgctga
     2341 acagttcaat gaagatattc cagaaacgat tcagcgagca caagaaatgg gggtaacgaa
     2401 aatggcggtc gtgggcttcg atacgccaac gattgaaaag tctttgcaat taagccatga
     2461 ctatccaaat atatacagta ttatcggctg gcatccgaca gaggctggca gttatacgaa
     2521 agaaatcgaa aataaattac aagaacaatt gactttacca aaggttgtag cattagggga
     2581 aattggcttg gattatcatt ggatggaaga cccgaaagaa gtccaagata aagtatttcg
     2641 cagacagatt gctatcgcaa aagaaatgaa cctaccaatc agtattcata ctagagaagc
     2701 acttgaagac acgtatcaaa tcctaaaaga agaagatgtt cgagatatcg gtggaatcat
     2761 gcatagtttc agtggtgatt atgaatgggc aaaacgattt cttgacttag ggatgcatat
     2821 ttcatttagc ggtgtcgtca ctttcaaaaa agcattagac gtccaagagg ctgcagcaaa
     2881 tgtaccaatc gaacgattac ttgtggaaac agatgcccct tatctggcac cagttccttt
     2941 tagaggaaag cgaaatgaac caggctatac tcgttataca gtagaaaaga ttgctgaact
     3001 tcggaatctt ccgacagaag aagtggctgc ccaaacatgg acaaatgcgc accgattatt
     3061 tggtctaagc gaacatggat aagatgaaga tccaagagat tatagtcgtt gaaggaaaag
     3121 acgatacaag aaggctgcgg gaagtagttg atgcagatac gatagaaaca atagggtctg
     3181 caatcaatga agagatcctg atgcaaattg aacatgccca agagactcgt ggagtgatcg
     3241 tttttaccga tcctgatttt tcaggagaaa aaataagaaa aatcattatg gaagctgttc
     3301 ctcaggcaaa acatgctttt ttgccgcgca cacaagctaa accaaagaaa aagggaagcc
     3361 ttggtgtcga gcatgcaagt gatgctgcta ttttagaagc attgaaaaag gtcgtgacgc
     3421 cagacatttc ccaaacggct gtttctgaaa tcactagaca agacctttta gactatggtt
     3481 taatagctgg ggcacaagca aaagaaaaac gagaaaaact aggtgacgag ttgcgcatcg
     3541 gttacacgaa cggcaaacaa ttggaaaaac gtttgaagat gtttcgtatt acgccgaaag
     3601 aactcgccca agcaatgaaa atagtggagg aacaacatga gtgaatatcg tgaaattgcg
     3661 acaccctcta gaacaaaaga gattttattg aaacatggtt tttcatttaa aaaaagttta
     3721 ggacaaaatt ttctgactga accaaatatt ttaaggaaaa tcgtagaaac tgcgcaaata
     3781 gatgaacata cgaacgtgat cgaagttgga ccaggaatcg gtgcattgac ggaacaatta
     3841 gccaagcatg caaaacaagt cgtagcattt gagatcgatg atcgtttgat ccctgtattg
     3901 gctgatacga tgcaacccta tgacaatgtg actattgtac atcaagatat tttaaagacc
     3961 gatttgtcaa cagctgttag agaaacattt catgaggagc ttccgttaaa agtcgtagcg
     4021 aatttacctt actatattac gacaccgatc atgatgcatt ttcttgaatc agatttggtt
     4081 gtggatgaac tagtcgtcat gatgcaaaaa gaagtagctg atcgtatctc tgctgaacca
     4141 ggaacgaaag cttatggttc attatcgatt gctgttcaat attatatgga agccagttta
     4201 gcattcatcg taccaaaaac agtatttgtc cctcagccaa atgtagattc agcgattttg
     4261 aaactgacaa gaagagatat accggcagtc gaagtgacag acgaaaaagc atttttccga
     4321 ttgacaaaag cggcatttca gcaaagaaga aaaacgcttt ggaataactt gcagcattcg
     4381 tatggcaaag atgaccagac aaaagcatgg ttagcaaaaa gcttggaaac agctggaatc
     4441 gatccaaaac gtcgtgggga gactttgtca ttacaagaat tcgccgcatt aagcaatgcg
     4501 atgtcagaaa atatgcagta aaaaaagagg ttgtgacaga agttgtgaaa aagctgtcct
     4561 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atgtttttcg tttgtttggg
     4621 cttattaccg cagatgcaag cttttgaaca ccgtttaaga aagaggttgt gggcctgccg
     4681 tttaactcta agtcacaagg aacaatttca aaaaacagct tctcatgttt ttgagttagt
     4741 tggtcttatt acttgatgca agcttttgac cactattatg ccgaacaagg agatgtgaca
     4801 caaattttgt cacatctcct atttttgttt cttgatcaaa aaattcttat acttgatact
     4861 cacactcatt ttgtatggat ttagaaaaga atatgtgtct tgacagttat tagtaagtga
     4921 gttatactaa gtcgacattt atgtgtcaag acatattagg agagagaaaa aatgagaaaa
     4981 aattcagttc gaaaactaac gatttctgct ttattgattg ggatgggggt cattatccca
     5041 atggtcatgc ctaaaatcat gattccacca gcttccttta ctttggcgtc tcatgtgcca
     5101 ttatttattg cgatgttttt tacaccagga gttgcagtgg ctgttgcgct aggtacgaca
     5161 tttggtttct ttttaacaac gccggttatc atcgcattgc gagcattgtc acatcttgtg
     5221 tttgcgttga ttggggcttg gtacttgcaa aagcatccga gtatcgtttt aaaaaatgga
     5281 cagtttactt ttgctaattg gcgtttccaa gggttcaatt ttgtgatcgg tgtgattcat
     5341 tctttagcag aaatgctagt agtcagcatc ttttacttta ttggtaatat gcctgaaaca
     5401 tattattctc aaggatattt ttatacagta ttcatcttga tggggattgg tgggcttatc
     5461 cacagtttag ttgattataa tattgcttat tttatagcag gaacactcag caaatatttt
     5521 gatatccccg tatttacggc agcaaaaaaa gaaaatcgga aagagtcgat tcaagggtac
     5581 gcgaagaaaa cgacatatta gacatgatct ctcaaaaaaa aaactctcat ctagtaatgg
     5641 ataataaatc ctctaagatg agagtttttt gtcctaaaaa gagctgcacc aacatcttct
     5701 ggcacagctc taacaggggg caatttatgg aagtttgatg acttgttctg tttctttatc
     5761 aaagaagtgg cctttgctga tgttgaaggc aaggtcgact atttcgcctg gtttatggaa
     5821 atctcttgca tctacttttg agatgaactc agtagaacca gtttttgtgt aaagcatcgt
     5881 ttcagctcca agtaattcgg aaacgacaac ttctgatttc actacggctt caggtgaagc
     5941 ttcaagggct acttgttcac tgtggatgtc ttctggacga ataccgaaga taacttcttt
     6001 tccttcataa cctttttcaa ctaatacttt gttttttcct tcaggaatac gaagcttaag
     6061 cccatgtcca tctgtgataa caccattttt caatgtcaca ttaaagaagt tcatggcagg
     6121 agatccaata aagccggcaa cgaacatatt gacgggtgta tcataaactt ctttcggtgt
     6181 accgatttgt tggataaatc cgtctttcat gataacgatt cggtcagcca tagtcattgc
     6241 ttctgtctga tcgtgagtaa catagatggt cgttgtttca agacgctggt gaagtttggc
     6301 aatctcagca cgcatggcta cacgtaattt agcatctaaa tttgataatg gctcatccat
     6361 taagaagact tttgcatccc gaacgattgc ccgtcccaat gccacacgtt ggcgttgtcc
     6421 accagataaa gcagctggtt ttcgtttcaa gtattctgtc agacctaaga tctctgctgc
     6481 attgtccaca cgttttttga tgtctgcttt atcatattta cgtaatttca agccaaaagc
     6541 catattatca aaaacagtca tatgaggata caatgcgtag ttttggaaaa ccatggcaat
     6601 atcacggtct ttaggtgcca cgtcattcat gacttttccg ccgatattta gttctccttc
     6661 agagatatct tccagtcccg cgatcattcg caaagtagtt gactttccac aaccggaagg
     6721 accaacaaaa acgataaatt cacggtcttt gattgataga ttaaaatcag ttacagaata
     6781 attttctgca ttgtcatatt ttttatatac gtttttcaga gccatttcta ccataatacg
     6841 ttccacactt tcttttttag ttttattaac tatttaaagt ataaatgaaa gcgttaacta
     6901 acttcaatgt catgttgaac aagaattttt tctttttttt gtcaatgtgc tagttttaag
     6961 ctttaataaa tatccataag aaataaaaac tgatacactg gagtaaataa gtatgttaac
     7021 aatatcaaaa ggagtgtctc ttatgaaaat cgctttgatc gctcatgacc gaaaaaaacc
     7081 tatgatggtg aaattagcaa cagcgtataa aacaatattg gaaaaacatg aactttttgc
     7141 taccgggacg actgggcaga ggatcacgga agcaaccggc ttgccgatcc atcggtttaa
     7201 atccggaccg ttaggcgggg atcagcaaat tggagccatg atttcggagg atcagttaga
     7261 tttggtgatt tttcttcgag acccgctggc tgcacagccc catgaaccag atgtaacagc
     7321 acttatccgt ttatctgatg tctatgagat tccgttagct acgaatatcg gaacagctga
     7381 ggtgctacta agaggactgg aagccggctt cctagatttt cgaagaatcg tccatgaaat
     7441 agacaagcat ccactttcat tttgatggat aagcgtatgg aaaaataacg tttaatgttc
     7501 gcctatatgt agctataaaa gctaaacaaa ctgataatat gcgatataat acgaacgtat
     7561 tggataatat aaacaataat attagttttt cgtatttgca gtaaatgtga aaatatgcta
     7621 tagtttctgt gggaaaagat cccaaaaata atacagagta gaaaataaag cgttaagtgc
     7681 taagaggatg ggatgttgcc tcttggacga aggacgtaat gttcgcggtt ttattttcgc
     7741 attcgctgca tgatacgatg tagcagctct taaaggagat gctaaaaatg aagaaacacc
     7801 ggttagacgc acgtatgatt gctattatgg gcttattgat tgcattgatg gtcactttgt
     7861 cccgactggt agcaatcgag accccattta ttaaaatcag tgtcacattt attccacaag
     7921 tgatcatggg cattcttttt ggtccttttt ggtcagggat aggcgcagtt ttagctgatt
     7981 tagtaggaat ggccctcttc tcgaaatctg cattctttat tggatttaca ttgaatgcat
     8041 ttattgaagg agcaatctac ggattctttt tctatcgaaa agagatcact tggaaaaatg
     8101 ccattctggc tacgcttagt gtcacgctga tcatcaactt atttttgaca ccattatggc
     8161 ttgcgttgat gtaccatgtg ccattgttca gctgggtcgt ttgggcgccc cgcctgttaa
     8221 aaacagtaat atggttaccg attcaatcaa ttgccattta ttacgtagga cgtagtattc
     8281 cttacaaaaa aatt
//
LOCUS       DADVXK010000110         8145 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.111, whole genome shotgun sequence.
ACCESSION   DADVXK010000110 DADVXK010000000
VERSION     DADVXK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.111"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            367..1905
                     /locus_tag="KB909_002436"
     CDS             367..1905
                     /locus_tag="KB909_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBB6838402.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            1902..2867
                     /locus_tag="KB909_002437"
     CDS             1902..2867
                     /locus_tag="KB909_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838403.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            2854..4176
                     /locus_tag="KB909_002438"
     CDS             2854..4176
                     /locus_tag="KB909_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6838404.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4239..4343
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4417..5160
                     /locus_tag="KB909_002439"
     CDS             4417..5160
                     /locus_tag="KB909_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838405.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5175..6167
                     /locus_tag="KB909_002440"
     CDS             5175..6167
                     /locus_tag="KB909_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6838406.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6179..6916
                     /locus_tag="KB909_002441"
     CDS             6179..6916
                     /locus_tag="KB909_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838407.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            6906..7628
                     /locus_tag="KB909_002442"
     CDS             6906..7628
                     /locus_tag="KB909_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6838408.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7712..>8145)
                     /locus_tag="KB909_002443"
     CDS             complement(7712..>8145)
                     /locus_tag="KB909_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6838409.1"
                     /translation="INLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETV
                     QTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLD
                     SSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         2606 a         1409 c         1771 g         2359 t
ORIGIN      
        1 acatttttgg caaaaaagtg tcatgataca gtataatatt cgttgaacag gccaataaag
       61 gtgttctccc ccacgagatt tctactttat tggctgtttc tttttattaa aataaaagtt
      121 gtgtgtgtaa aaaagatata gctgattcca agtgacaatt tcgtatagat ttttatggta
      181 ttcgtagtga aaaaacgaga accaaaaagt tgatccgact ttgttgcttg gattcttttt
      241 ttgtcagcat atttagaggt atttttttct tttttttgtt cgtgctgtaa ggttaaggca
      301 agacaagtta gttgggaaaa aggaaagaaa tgtttatact taaagaataa cagaaaggaa
      361 ggtcgcatga ataattttat acaaacatta agtgaaagaa aaggcgagtt gctggaagct
      421 gcatttcaac atctgtccat ttctctcatt tctttgctga ttgcagcact gattgctatt
      481 cctttagcga tttgggcagc caatcataaa aaaatggcag aagtcttatt gcagatcacg
      541 ggtgtgctcc aaacgattcc ttcacttgcc ttattaggtt tacttatccc atttgtaggg
      601 atcggaactg ttccagcatt gattgcactt gttatttacg ctttgcttcc gattttccaa
      661 aacacgtata ttggtctagc tgaaattgac ccgtctattg aagaagcagc ggtagcattt
      721 ggtatgtcca gaatgagacg cttgctgaaa gtagagcttc ccatcgcatt acctgtcatt
      781 atctcaggta tccgaactgc cttagtttta atcatcggta cggctacttt ggcagcattg
      841 atcggagcag gtggattagg gacatttatt ttgttaggta ttgaccgaaa tacacctgtt
      901 ttgacattga ttggtgcgat cagttctgcc ttgcttgcaa ttatattcag cggactgatt
      961 cgctggttgc agcataagaa acctcgatat tccatcatta ctttagcagc agtggtgtgt
     1021 ttatttggcg gcgtttcttt atatcagtct gccttgttta aaaatgaaac catcacgatt
     1081 gctggaaaat taggagcgga acctgaaatc ctgatccaaa tgtataaaga attgattgaa
     1141 gacaacacaa aaacagaagt tgaattaaaa ccgaattttg gcaagacgag ttttttgttc
     1201 aatgcactgg atcaaggtca aatcgatatc tatcctgagt tcacaggtac tgtcctagaa
     1261 agcttggtga aggtacctga agcaatgaaa agtgctgatt tgacaaaaga aaaaacatat
     1321 gacgaagcag aagaattatt gaataagcaa ttcgatatga cattattaaa accaatggct
     1381 taccaaaata cgtatgcctt ggcagtcaag agatcttttg cgaacgaaca tcaacttaaa
     1441 aagatttccg atttggcagc tatctctgat cagatcaaag cgggattcac actggaattt
     1501 attgatcgtt cagatggata taaaggaatc caagaagcat atggcttgaa tttttcaagt
     1561 gtacaaagca tggagccaag tttgcgttac caagcaatca ataatggaga tgtcaatatt
     1621 gtggatgcct attccacaga tagccagctc aaggagtacg atctagtgac tctagaagat
     1681 gatcgagggt tattcccagc ttatcaaggc gcaccgctga tgaaaaaaga ttttgctaaa
     1741 gaacatcctg aaatcgttaa agcactgaat aaattaagcg gaaaaataac agaggatcaa
     1801 atgattgata tgaattacca agtcaatgtc gaaaagaaaa agccgacaga agtagcacga
     1861 atcttcctga aaaatgaagg attagtaaag gaggaagatc agtgactaaa ttaatcgagt
     1921 tcaaacatgt gcaaaaaaag tatgatggaa agtatgtcat cgatgaccta aatctggcaa
     1981 tcaaaaaagg agaaatcttt gttttggttg gtccttccgg tagtggaaaa acaactactt
     2041 tgaaaatgat caatggatta tctaaaccat cagcaggaga catctacttc aaaggaaaat
     2101 cgttaaatga atataatctg cagaaaatgc ggtggaatat gggatatgtg ctgcagcaaa
     2161 tcgctttgtt cccgaccatg acagtcaagc aaaatattga agtcatccct gaaatgttag
     2221 gttgggaaaa gcagaaaaga gcagaccgtg tagatgaact tcttcaaaaa gttggcttat
     2281 ctcctgatat ttatcgagat cgtatgccta gagagttgtc tggaggagaa cagcaacgga
     2341 tcgggatcat ccgagctatt gctgcaagcc cagatgtgat tttgatggac gagccattta
     2401 gcgcattaga tccgatttca agaaactcat tacaagaatt ggttttgtcc ttacacgaag
     2461 aattgggcac gaccatcgtt ttcgttacgc acaatatgga agaagcaatc aagctaggtg
     2521 atcgtattgc atttatgaag gatggagaaa ttatccaatg tgacacacca gagcagttat
     2581 tgatgaatcc taaaaacgac tacgttcggc atttctttga tgaaccgaaa cagacgaaag
     2641 agtggcgagt agaagattta gtcgtcaatg gatatttctt aaatgaaata ccagaaaatg
     2701 ctcgtcaaca agtttgcttt gatacgccta tgaaagaagt atattcgctt ctttcggtgt
     2761 atccaagcat tgtgatagta gaaaagcaaa gaagtattgg gtcgctgaca agtaaagaaa
     2821 tctttgcttt tttaagtcga gaggaggaag gaaatgaaaa catatgatgc aatcatcatc
     2881 ggttcaggtg tgagcggctt aagtgctgct tatggattga aagaagcagg taaaacagta
     2941 ctagtggtcg aagaagatct atggggcggg acttgtccta accgtggatg tgatcctaaa
     3001 aaagtcttgt taagtgcagt agaggcacgt aatcgggtaa aacaattgag tggaaaaggt
     3061 tttaacgaga tcccaactgc caactgggaa gaacttcaaa aattcaaacg aacatttacg
     3121 gatccagtcc cagaaagccg aaaaaaacaa ttagcagaag ctgaaatcga tcatctttca
     3181 ggaaccgctc gttttttgga tgattcatct attgaagtca acgaagaagt cttccatgcg
     3241 gattacttag ttttggcaac cgggcaaaga cctacgatct taccagtgga gggaaaggaa
     3301 tacttgaaaa ctagtgcaga ctttttatca ttgcctgtac tgcctaaaga aatcattttt
     3361 atcggtggtg gttatattgc ttttgagcta gctacgattg ccaatgctgc agggagcaaa
     3421 gtaaccattg tccatcataa tcaacggcca ttaaaagaat ttgaggcgtc tttggtagag
     3481 gaagccgtcc atcaaatgga agcatctggc attcagtttg cttttggtgt tgaaacccaa
     3541 aagatcattt cagaaggtac tcgctatcgt ttagtcggaa aagagacgga attagtagca
     3601 gatatgattt tttgtgcgac tgggagacag ccgaatacag aatctttagc acttgagcaa
     3661 gcgaatatcg tctttgataa acacggaatt gcagtcaatg attatctgca aacgagcaat
     3721 ccaaaaattt ttgcgtgtgg agatattgtt tcaaggaaaa ccccaaaatt gacaccagtc
     3781 gccacttttg aaggaaatta tgtagctaag cggataacgg atgcaacaag cgaacctatc
     3841 aaatatccga ttatacctac gatcgtctac gccagtccta aacttgctga agtaggagtt
     3901 acaaaaagtc acgcctcttc gtcagatcaa gtggtagaga tggatcttac cagttggttc
     3961 acctatcatc gtgtcaatga accagttgct aaggctgaat tgacctttga ccagcaaaat
     4021 tatttgattg gtgctgcagt gattagcgag caagcagacg aattgatcga tgatttgaca
     4081 ctcgtcatca atcaaaaatt gactaaaaaa gagttggata gctatatcat ggggtatccg
     4141 acattggcaa gtgatctctc ctatttattg aaataatcag catgataact aaagcgcttg
     4201 ttgctttttc cttcttgtgc tacactttaa aaaatgaata cctgtttctg gggatgtcgt
     4261 agacgacatg agagtaagtt gtgaacttag acccattgaa cctgtcagtt aatactggtg
     4321 aagggagaaa catagcagac gcttgaagcg ggttactatg tcgtgcccat ttcaagcgtt
     4381 ttttgttatt catattagaa gaaaggaggt aacaaaatga agaaaaatct ttatccagca
     4441 gtcagtatgg cattcatttt aattatttgg cagattgttg tcatagtttg gaaaatacct
     4501 gcctttattt tacccggacc tgctgctgta ttttctgcat tagcggcaga tgcacaagta
     4561 ttactttccc attctgtcac gacattaaat gaagcagtgc ttggtttggt aatagctagc
     4621 gttctttctt ttattactgc cttggcaatg gattattgga agtttttaga aatgtctttt
     4681 tatccgttac tagtgatttc acaaatgttg ccaatcatgg tgttagggcc attacttacc
     4741 ctatggtttg gtttcggtat gcttccaaaa gtgatccttg ttgtcttgat aagctatttt
     4801 ccgatcgtag tttctttttc ggatacattg aggaaagtat caaaagagca aatcatcttt
     4861 ttgaaaacga tgggggcaga tacagggaag atttatcgaa tatataaaat accagcgggt
     4921 ttatccggct tcttttccgg tttaaaagtg gctgctactt attgtgtcag cggagcagtc
     4981 gttggagaat ggctaagcgc tcaagcaggc ttagggtatt acatgatacg cgtaaaaaac
     5041 agctaccaga tcgataaagt ttttgctgcg atcatttgtg tcattctatt gagtttattg
     5101 ctgaatggcg cttgttcatt attgaaaaaa gggtattatc gtatgcttta tattttttaa
     5161 gagaagggga tcaaatgaaa aaattatggc ttttattacc gctactgttg cttttatccg
     5221 cttgtggcac tgcaaaagaa acaagtagca aacaagaaat aaaggatttg aaaaaagtga
     5281 cacttgtttt ggattatgta ccgaatacta atcatactgg catctaccta gcaaaagaaa
     5341 aaggctatta taaagaggct ggtttaaatg tccaaatcat cgaaccagga gataattcga
     5401 caagtattgg tctagtaggt gcggacaaag cacaatttgg tgtaagttat caagaagatg
     5461 tcacttatgc tcacgcagat ggacagaata taccagtcaa agcaattgct acagtgatca
     5521 aacataatac ttctggattc gccaccctat cagacagtaa catccattca ccaaaagatt
     5581 ttgaaggaaa aacatatgca ggttggcaaa gtccaagtga agaagctgtc ttaaaagctg
     5641 tgatggaaaa agacggcggg gacttttcaa aactgacaat ggtaggaagc aatggagaag
     5701 ggccagaaag cttaggaaaa tcctcagata tccaatggta ctttgaaggt tgggatatga
     5761 tcaaagcaaa agaagcgggt attgaactaa actatatccc attgaaagaa ttagatgaac
     5821 ggttagatta ctatactccg gtaattatta cgaatgatca actgatcaaa agtgatccag
     5881 aattggtaca gtcttttatg gatgccacga aaaaaggcta tcaggaagct attaaggatc
     5941 caaatgacag tgctaaactg ttgcaaaaat atgcaaaaga aaatgatcgg acgtttttag
     6001 aagaatcaca agcattcttg tcaaaaaatt atacggatga tcctgagaat tggggattga
     6061 tggaagaaaa agtttggcgc aattatacag cttttatgca ggaaaacgga ttgatcaagc
     6121 aagatgtacc ttcgcaagaa ctattcacta atcagtttat aaaataggag tgatagatat
     6181 gtcaatccaa atcagccact tgaatgtagt cattgaaaac ctgaaaatat tagaagacat
     6241 ccatttcact atccctaaag atacctttac atcgattgtc gcgccaagcg gagccggtaa
     6301 gtcaacattg ctgaaaactt taacaggagt ccagcctatg acttctggaa cgatcaaagt
     6361 agacgatcaa aaagtaactg gtctccatac agcatttagt tatatgccgc aagaagatat
     6421 gttacttcct tggctgagcg tctatcaaaa cgttacgtta tatcaaaaaa tcaatcatct
     6481 aacaatcaat gaagaacaag taagggatta tctggatatc tttgggttaa acggctatga
     6541 acattttttg ccggaacaat tatctggcgg gatgaagcag cgaacggcct tgttacgaac
     6601 aatcatgaat ccttcttctt acttgcttct tgatgaacca tttggagcgt tagatgctat
     6661 gaccagaggg cagatgcaag actggatgtt gaagctgcct aaaaaagcaa agcggactac
     6721 tttacttgtg acgcatgata tcgaagaagc aatttattta tcagacagga ttcttgtgct
     6781 ttccgcccgt ccggcacatg tgattgctga gattcaagtg cctgaaaaac gacggtcacg
     6841 tgaatggcta ctgcagcaat cagagttgaa gcaaacgatt tatcagttat tggcaggtga
     6901 attagatgtt aagtgatgct cattgtcatt tagatgggag tcagagttta gcactccttc
     6961 agcaggaaca cacgattttg acgatcatca attgtgattc gccagaagaa tggaaggaaa
     7021 acagacagct tgcagcaagt aagactcaag ccttaagtta cggtatccat ccttggaaag
     7081 cagatagcta tacgtttgaa caagttgagc cttttttgaa aaaagcaagg atcatcggtg
     7141 aaatagggtt agataatatt tggacgaatg taccgatgac tacacaaaaa aaagtatttg
     7201 agcgacagct tgcttttgca gccataaatg agaaacctgt tgtactgcac acaaaaggat
     7261 gcgaaaaaga gatcttaaat tatatccaag cttaccctaa tcactatttg atccattggt
     7321 attcttcttt ggactatcaa caagactata ttgatttagg ctgttatttc agcattggtc
     7381 ttgatttgaa aaagaatcca gcagtctggc aactagctaa agcagtccca atcgaccact
     7441 tacttattga aacggatgga ctacatgcag cagagtgggc tttagggggg attttttcag
     7501 aaaaagatta tgtctcactg cttgaagaac agttaaagac aatcgctgag atcaaagagc
     7561 tatcagttga agaagttaaa aaaaatactt atcaaaactt ggaacgtttc attagattag
     7621 gtaaataaaa aagagatgtg acacaactag tgtcgcacct ctttttggct ttctttgtat
     7681 aaaagtaaac tgtttgatta ataaatgaat cttagtacca accgtttgct tcccagaatg
     7741 ctttcgccgc ttcccaagaa ccataacgtg aagtaacata ttgttctgct actctttctt
     7801 ggtttgcagc agagtagtca ccatttaagt aagaagaatc taattggtaa cgtccgatgt
     7861 aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt ttgtgcgatc cattcttttg
     7921 cagagcttgt gcttgctgga gtagcagcag tttctgttac agcaggagca ggttgtgttt
     7981 cagcaacagg cgctgcttgt ttttccgttt gaaccgtttc ttgtacaaca ggttgttcag
     8041 cttggactgg tgcttcttga acggctgctt gaggttcagc agctgcttgt gcagagcctt
     8101 ctgttgggat tgttaattgt tgtcctgagt aaatcaggtt aatat
//
LOCUS       DADVXK010000111         8039 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.112, whole genome shotgun sequence.
ACCESSION   DADVXK010000111 DADVXK010000000
VERSION     DADVXK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.112"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..586)
                     /locus_tag="KB909_002444"
     CDS             complement(<1..586)
                     /locus_tag="KB909_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6838410.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLL"
     gene            complement(588..1352)
                     /locus_tag="KB909_002445"
     CDS             complement(588..1352)
                     /locus_tag="KB909_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBB6838411.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1360..2037)
                     /locus_tag="KB909_002446"
     CDS             complement(1360..2037)
                     /locus_tag="KB909_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBB6838412.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2074..3459)
                     /locus_tag="KB909_002447"
     CDS             complement(2074..3459)
                     /locus_tag="KB909_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6838413.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3669..3753)
                     /gene="ffs"
                     /locus_tag="KB909_002448"
     ncRNA           complement(3669..3753)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KB909_002448"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3776..4291)
                     /gene="tadA"
                     /locus_tag="KB909_002449"
     CDS             complement(3776..4291)
                     /gene="tadA"
                     /locus_tag="KB909_002449"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBB6838414.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4397..5254
                     /locus_tag="KB909_002450"
     CDS             4397..5254
                     /locus_tag="KB909_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838415.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5335..5670)
                     /locus_tag="KB909_002451"
     CDS             complement(5335..5670)
                     /locus_tag="KB909_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838416.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5737..7107)
                     /locus_tag="KB909_002452"
     CDS             complement(5737..7107)
                     /locus_tag="KB909_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBB6838417.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7185..7721)
                     /locus_tag="KB909_002453"
     CDS             complement(7185..7721)
                     /locus_tag="KB909_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6838418.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         2333 a         1699 c         1291 g         2716 t
ORIGIN      
        1 ctaataatac aaaaaataag ataaagctat gcatgaaaaa ttcttctgga agtacattga
       61 tgattggatc agtaacggga tcgaataacc agtcatcgtt gttgaaaaac gtttcatgaa
      121 aaaggataaa aaagcgatca aatcctatca tcatgaaaaa accgaaaaca actggcagta
      181 acatgccgat ttgaaacgga cgaatcaacc gccaaagccg atcattcttt tgcaaatatt
      241 tgataaacaa aatactcggg atcaaagtga tgaaaaacac agcataatcc actaaaaaca
      301 aaattttcac ttcataaaag tgatgggctc cgctagcaga aactgggaaa tctggcaagc
      361 tgaggatggt tttgaaggga ttattgagat aattcattag gtgatcaaaa tttttcagta
      421 acgtctcttg atctaaagaa gtataatcca aaatttgcaa atgtccgata tcaaatacgt
      481 atagtggtcg aaagttgatc gtcacaccaa ctgccagact gatcagtgtc agaaataggc
      541 tgaacaatcc agcatattcc atccactgcc atctcgaatt tttcatatta gaagctccat
      601 tcatccagtg attgtttcac ataggtagct gggataggca acccaggtac atcttcttct
      661 tttgtaaaac ctgataaaac gagcaaagta tctatattat tgcgtatccc agcttggata
      721 tctgtttcat agttatctcc aaccatgatt acttcttctt tttgcagccc taatacttca
      781 acggctttat ccataatgat ggcttctggt tttccgatgt agatcggcgg cgtttgggtt
      841 gctgtctcta caaaagagat gactgaccct gctccaggaa gaaggccgcg ttcagtaggt
      901 atattcttat ctgggttcgt tccaatgaaa gtagcacctt tttgaatagc aagtgttgct
      961 ttaactactt tttcataggt cagataatta tctaagccta ccactacata gtcaggagcc
     1021 tcttcttccc atgtaaatcc ggcagctaaa atcaagtcaa tcaatcctgc ttctccgata
     1081 acatagactt ttttcccttt tccatctgct ttcataaaat cgattgttgc caaagtagct
     1141 gtgtagactg tctctggagc tacatgaatg tcaaactcat ctgctagacg attagctact
     1201 gtttctggtg acttagtcgt gttattggta acaaacaaga aaggtaattt tcttttttgc
     1261 aattcttcca caaatcgttt accggccggt atgggttgtg tcccacgata aatcgttccg
     1321 tctaaatcaa ttaaatatcc tttatagtcc attcatccac tactcttccc tttttctgat
     1381 cgtaaatgct gtttttgttt tttctacttg tttaggttgt tcttgttttt ttactttttc
     1441 agaggttttt gctgactctg tttttcgatt tttaataacc ggttttttgc gattagatgc
     1501 gactggtcct tttttctcat cgatatacgc acgattatgg ttttttttct tttttcggcg
     1561 ctgagttgtc ttttcttttt taccgccgat tctctcgatg acaaaatacg cacaaccaaa
     1621 attgcaatat tcgtaaagat agtcttccaa ggaatcgatt cgctgatctg gatgcgcccg
     1681 tcgattatcc gcttggaaaa atccttttag gcgtagttgt tcataacccc aatctcctac
     1741 gatataatca tatcgggcta gtacatcact gtaacgttct ccaagctttt ctgcattaaa
     1801 tccttcacga taatcggaca caagccgata atgtctttca cctatcaaaa aattactgtc
     1861 atctaacagt gtcactagct cgcctttgac tttttctgct ttaggctcct caacgatttc
     1921 ttccaaagca gctgtcagtt cttcggtgac tgttgtttcc tgttcagctg atgatttttt
     1981 cttagcaatt tctgttttat gctcaacgtt ctgctgttca ttttgttttg cagacatgcg
     2041 ttcaccacct atctttttta ttataccttg tttttatttg attgggtagt gagctttcaa
     2101 gtaatctcct accacacttc ggataaattc agggaacaaa aattcatttt ttccagcaat
     2161 ctcaatcgtt ggaaaaaatg gaacaaacat caaatgatct acggtagtaa aagtataatt
     2221 tttattcaga tcgattggct tgttcttcca aaagacttga tggttaatag aatcatatgt
     2281 gattccatta tagaccatct gcccaaaaat cttaccgcga aatcccattc ccttcatagg
     2341 atagttacgt aaaaagttac gatttttttc tatttctaaa actaagcgga tcagatcatt
     2401 tccacccaat gtgacattta acaagtgcat cggatgcggc aacgcagtgt gaagctgatc
     2461 ctgattgacc cgcccttttg gaatttcagt taaaaacaga ccactgttta atattgctgc
     2521 ttccgtcttt cctcgttctt tcaccgcctc aaaggctact tggataaacg aatgctcatt
     2581 gaagatatct agactcagag aaaatggcaa atctgctact tctttttctt ttaataattc
     2641 atgcccacgt tctagacaac tatttatttc ttgttcatct tctgtaaaag ctgtcattgt
     2701 ttcggtaggg atggctttgg ctgaatgctt aaggattttt ttctcttcat cgatggttaa
     2761 atggacttca ccgacatact gcccgtactt tccagcggct gctatttgga catcattgat
     2821 tacgtgacct tctctgaata aatgatgggt gtgcgatcct aaaataacat caattgctgg
     2881 tatttctttt gcaatttgga aatcatcctg aatcccgaga tgactcatca aaactaaaac
     2941 atccacttgt gaacgtaaat cttcgactaa ttctggcaaa atatcataag gattccgtat
     3001 gtcccagcca ttcggattat aagtaagcgg aaatggagca gtaaatgcaa ttagtccgat
     3061 tttcgtctgg tgtttcgttg taatgatttt atatggtttc gtccatgccg gtggctggag
     3121 cgtattttta tcgaataagt tatccaggat gatatcaaac tcagcatgat cgtataaatg
     3181 attcaactct tctttggaat ttcctacgcc ttcattgttt cctatcgtcg ctgcatcata
     3241 accaacttca ttcatcagca agatattttc ctgtccattc gttgcttctg acaatggatg
     3301 ccaacgatcc acaaaatcac ctagatctac tgcaatcgtt gtcgtttttt ctttcttttc
     3361 gttttctcgt ttacgttgat ccaaaaacct tctgatcctt ggccaatttt ctaaatgaga
     3421 atgcagatca ttcgtatgta aaatcactat tttttccatg taccctctcg cctctcttta
     3481 tctttatcat accataggca gctttttctt ccattgaaac aagctctatt tcagagtttt
     3541 tcctgccttg aagcaaattg tataagtaca atattcgata aatcagtctg gctaaaaaat
     3601 caggaacatt catttttaca gtactataaa aataaaaaaa acagacccga aagtctgttg
     3661 tcgtttcatt ataatcagac acatggcgga acctgcttag tgctgcttcc ttccagacct
     3721 gacacgcttc acaagcccac cattgtccta gcctttcggc aaagaatagt ataccttatt
     3781 tttcattcgt tgaccagtct ttttttaatt tcttttttcg ctggcggagc tttcggaaaa
     3841 agtcagtcaa aatcatccca cattcgtctt ctaaaatgcc accttctaca tatgcttggt
     3901 ggttaaaccg ctcgtcctcc aaaagattca tcaaggtacc ggctgttccg ccttttggat
     3961 catacgcgcc gaaataaact tctgctacac gagacaaaat catcgcgccg ctgcacatag
     4021 gacaaggctc taaggtaaca aaaagtgcag catcttccaa gcgccagctt cccacttttt
     4081 cacaggcttc cttgattgca agcatttctg catgtgtagt agcatcttgc gtggtttctc
     4141 taaggttata tcctcttcca atcacttttc catccaatac aaccactgct ccaatcggaa
     4201 cttcatgaag catttctgct ttctttgctt ctgccaatgc aaggcgcatc catttttctt
     4261 tttctactgc atcaagattt gtatttacca attacccttc cctgcctttg ttttttcttg
     4321 ttttacttta gcatatgata aaaaggctgt aactaacttt ttttctatgg taaaataaat
     4381 acaagaggtg aacaagatga aaatggataa attacttgct ctttacccac aagcacagaa
     4441 aaaaaactct ccagcatcag aagcggatat cctttctttt gcaattgatg atgcttttat
     4501 ctggatcaaa caagattcat tatctcaaca agaaaccagc cttttgaaag cgttattccc
     4561 tgtaatcaac gatcaaaaaa aacacccatg gtatcactat ctttttaaag atgcttcttg
     4621 tgttcaagaa aaaagctttc gtttgatcca gcttcacgtc gaatcaaaag gagaattctt
     4681 aaaaaaagaa tggcaagata ctattttgga attatttcgc tattctgctg atttcttttt
     4741 ttatacagac acagatgcgc tcttagtcga acaaataaac cgtgattatc ttgatgctac
     4801 tgaaatcaac ggtatttttc tatctttaga tgctgatttt gatacgacaa cgtctgtatt
     4861 cgttggttct ttccattcac ctggcaccga cctcgtccct ttgtttgctg aagaaagaaa
     4921 aattttttta acagagcaaa acaatcttta tactcacagc cgtacttttt ctatgcaaga
     4981 tgtggcttta cattactata caaaagatac tgtaaaagat agtaagttga tcaaaagtta
     5041 catagaactg atcaaacaaa atgaaatgga agtgatcatt caagaattat ggaatgaatt
     5101 aggcaatgtc agctctgctg caaaaacact gtttcttcat cgtaatactc taaaatatcg
     5161 aatcgaaaaa tttcaagaac agtctggttt caatctaaaa aaagccaacg atttactgtt
     5221 ttgctatctt ttattgcttc atgaacataa ttaaagatag attaaagggg ttgtgacaat
     5281 aattttgtca caacccctta tttcgaatga atagtgttca aaagctagtt tctcttacat
     5341 cattttttca acaaaatgca ttagccggtc ttttacatct tcggttgaat ctttgattga
     5401 atcaccataa acagagattt tcttttttcc tgatttgatt tttgctaaca ttcccatcaa
     5461 agaatccaag tcactatctg aaagaccatc tacgatttct agtaattttt catttccatc
     5521 aaatttgtca tagacgaatt tttttacttt cgtccgagta gtcatatgat ggatcttttc
     5581 cattactttt cccgatacaa cgactgctgt cgctacactg gcagcggctg ctacgcttaa
     5641 tccgattgtt acttttgttg atgttttcat aagtatcagc tcctttttat ctatctccat
     5701 catagcatag acaaaaaaat aaacgaacta atccactcag tgaaatctca atcctttagg
     5761 gaaaaagttc tttactgttc cttttacttg tttcccaaat ccgacaggta tcttatctaa
     5821 tactagcaaa acccatcctt gattcccatc acgttgaaat gtttctcctg ctgtgtaaga
     5881 ttgccattcc ttttgagtga tcggcaagca aggtatattc tctatctttt ttgtagcaag
     5941 cgctaatgca tagctaggtt caaatcgatt ctttttgaaa tctcctaaat gcaaacctgt
     6001 acgtacgact tttaaaccat cgagagaagg ggctaactca ggaacttccc aaagatggtc
     6061 gttgaacact aaaagtcttc cagtagcttc ataatgaaaa tcatttgaaa actccgtcca
     6121 gagtttttcc tgctcttttg tcatttgcac tttacttttt tttcgtgtct tcttttcttt
     6181 atgcatctga ttttgtccat gaaaagtcag ctttgcaaca aaatgtcctt caccctgatc
     6241 tttatgaggc catatacgta ttgttttttc caaaccagct acgcttcccc attcagaacg
     6301 tcctgaacta acggattgag tcaaaggaat ctcctcaatc gttactggat aattttctac
     6361 aagccagcta atgatctctt cattttcttc tggtgcaaac gtacaagtcg aataaatcag
     6421 ttgtccttta ttttttagca tttttattgc tgaagacaaa atctcttgct gacgtttttg
     6481 acagtatagc ggagattctt ctgtccactc ttttattgca tttggatctt ttcggaacat
     6541 tccttctcct gaacaaggag catcaaccac gatccgatca aaaaagcccg aaaaatgagg
     6601 gacaagttct gcgggtgcat gatttgtcac tattgcgttc gaaactcccc atcgttctat
     6661 attttctgat aaaatcttcg cacgtttcgg aaagatctca ttcgtcacta ataacccttt
     6721 ccccttcatt tgagcagcta attgggttga tttaccaccg ggagccgcac acaaatccaa
     6781 aactttttca ccgggttttg ctgcagcagc tgttccaacg atcattgcac ttggttcttg
     6841 gctatattca tacccagctt gatggaggaa agactttcca ttgacagtgc caagaaatcc
     6901 ctcattgctg tagggagcgg gttgtaattc ttcgctatgg taagtttgga ccatgtccaa
     6961 tcctgccggt tttagtggat tccaccgaaa tccttttttc acgcttcctt gttcaagcgc
     7021 agaaaaaaaa tcggatgctt cttcgcctaa aagaagacga tattttttga taaattgctg
     7081 tggtaacgtt gtcgcttcct ccttcattcc aatgtttcgt tagacatttt acaatctttt
     7141 ttacgaaaaa taaaggtggc tgatctactt tttcatgttg ctgcctaagg tgactgttcc
     7201 tttaagatat tttccaagta ttcatccgtc acctcgtttt tatcccaaac agcgttcatc
     7261 atttcaagaa aatcttgaga agaatcatct gagcgcaaac ttcccaatgc attaagccat
     7321 accaattcaa gcgacttttc ttctttgatc ttcgtgtgac ctttgacata tgagaaaaat
     7381 ggccgcttaa atagcgaatc catgtctaaa tcagattttg caatgatttc acgaatactt
     7441 tcatggatag aaaaaaaatc tttcaataag tagacaatgc ttaaaacatc atcggaactg
     7501 cattcagcta agtagttttc aaaataaaca gtgatttctt ctaatatctt ctcttttaac
     7561 ccgctgattg atttgaaatg tgtataaatc gggtatgtag aacaaccgca gaactctgct
     7621 aactctcttg cagtaattga cttcattcca tattcttcca cgtataccat acttttgaac
     7681 agcaaatatt ctttactata atttgttact ctccccatca ttcttacctc cgtctctttt
     7741 catctaccca taaataaata acataaataa ttctaaaaat attattgata attatcaaaa
     7801 catatttagt tatatccatt aaaaatcaat ttttccgcct taaaaacaag aatatcttga
     7861 caaaataccc taggaaataa acaatagaat aaacaaggta acaaaaaaat taaataacgt
     7921 tatataaaaa agaaggcgac actctgtgag aataacacag actgaaatga ctttccactc
     7981 acagtttttg tctaactata tacaaaaaca gaataaaaag gaggtattta tgctaattg
//
LOCUS       DADVXK010000112         7939 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.113, whole genome shotgun sequence.
ACCESSION   DADVXK010000112 DADVXK010000000
VERSION     DADVXK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.113"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..442
                     /locus_tag="KB909_002454"
     CDS             <1..442
                     /locus_tag="KB909_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6838419.1"
                     /translation="HRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVMALTIAKPA
                     DCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFGGVSKKSES
                     KQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            456..1205
                     /locus_tag="KB909_002455"
     CDS             456..1205
                     /locus_tag="KB909_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6838420.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            1205..2035
                     /locus_tag="KB909_002456"
     CDS             1205..2035
                     /locus_tag="KB909_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6838421.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            2035..2682
                     /locus_tag="KB909_002457"
     CDS             2035..2682
                     /locus_tag="KB909_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6838422.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(2780..3556)
                     /locus_tag="KB909_002458"
     CDS             complement(2780..3556)
                     /locus_tag="KB909_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6838423.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            3700..4659
                     /locus_tag="KB909_002459"
     CDS             3700..4659
                     /locus_tag="KB909_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6838424.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            4776..5084
                     /locus_tag="KB909_002460"
     CDS             4776..5084
                     /locus_tag="KB909_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6838425.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            5111..5410
                     /locus_tag="KB909_002461"
     CDS             5111..5410
                     /locus_tag="KB909_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBB6838426.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            5584..6135
                     /locus_tag="KB909_002462"
     CDS             5584..6135
                     /locus_tag="KB909_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBB6838427.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            6281..6574
                     /locus_tag="KB909_002463"
     CDS             6281..6574
                     /locus_tag="KB909_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838428.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            6567..6863
                     /locus_tag="KB909_002464"
     CDS             6567..6863
                     /locus_tag="KB909_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838429.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            6934..7938
                     /locus_tag="KB909_002465"
     CDS             6934..7938
                     /locus_tag="KB909_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6838430.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
BASE COUNT         2794 a         1168 c         1490 g         2487 t
ORIGIN      
        1 ccacagatta cttcatggac aagtaatatt ttcttggact aaacagtatg atattaacca
       61 tattattgtg gctgataaca aagttccagg agatccaatg tctgtgatgg ctttgacaat
      121 tgctaaacct gctgattgca aattagacat tgttaaaatt agtgatgtta aagggattat
      181 ggaaacatcc ccaaatgata attacatgat tttaattaaa ggacctaagg aagcttttga
      241 attagttcaa aatttaccag aaattaaaga aattaatttt ggcggtgtgt ctaagaaaag
      301 cgagtccaaa caatatggaa aggcagtctt tttaactcct gaagaattag aagccacaaa
      361 aaaaattctt gatcaagaag tgaaaatatt tgtgcaacaa gtcccatctt caagtattga
      421 aaatgtagat tttagtaagt aaggggggaa aataaatgtt attaaaagcc attttattag
      481 gtttagttgg tgtggtagct gttattgact ccaggttaat tggtcgacaa aatattggta
      541 gaccactaat tttgagtaca cttgccggac ttgtgctagg tgacttgcat acagggattg
      601 ttcttggggc atctttagaa ttaatttcta tgggattcgt ctcaattggg gcggctggac
      661 ctcctaatat gcaacttggt agtattattg ccactgcttt tgcaatttta actaatagta
      721 gtacagaaac agccttaaca atagctatcc cagtggctgt agctggtgaa tttatgagta
      781 ttatcatgcg catgataatt gctcaatttg gacatgctgc agataaagcc attgaaaata
      841 ataaatttag aaaagctcaa attattcata tttattggtc atttattttt aatgcttttg
      901 tttactttat tccaatcttt ttaacagtat attttggtgc tgacgttgtg gcagatttag
      961 tagataaaat tccagaaatg attacagacg ccttgactgt ctctggaaat atgctttccg
     1021 cattagggtt tgcaatgcta ttaagcacaa tgttgagtaa aaaattatat ccttacttta
     1081 tttttggatt ctttattgtt gcctattcag gtctttcact aattggcgtg acaatttttg
     1141 cagctctgat tgcctttgta atggatcaag ttaaatatgg aaaaagagaa gaggcgcatg
     1201 gttaatggaa aatagtacag aaaaaaaacg tttaatcaca aaaaaagatc ttaataagat
     1261 gtgtcttcgt tcatggacaa tcatgtgttc gtggaattat gaaagacaaa tgcatatggg
     1321 atttatgtat gggatggcgc caattttaaa taaagtttat aaaaatgatg aagagaaaaa
     1381 aagagaagct tatactcgtc atatggcatt ttttaactgt acgcctcaaa tgacttcatt
     1441 tattatggga ctttgtgctt ctatggaaga acaaaatgct caagcagaag aaggaaactt
     1501 taatactgaa tctatctcca tgattaaaac cagtttaatg ggtccttttg ctggaattgg
     1561 tgattcattt ttccaaggta ctttaagaat tattacattt gggattggat tgtcttttgc
     1621 taagcaaggt agtattttag gaccgatttt agctgttggc ctttttgcta taccttctat
     1681 tttagctgtt ttttacggcg gtaaattagg atatgagtct ggcaataaat accttactaa
     1741 attgtatcaa gaaggtctta tggatcgagt aatgcaattt gcttctatca ttggtttggc
     1801 tgtagtaggt ggaatggtgg ctagcatggt gccaattgtc acccctttaa aattcactac
     1861 agggggaaca gaacttgttt tacaagactt acttgattcc attattcctg gattattacc
     1921 acttgtatgt actttgggaa tatataaatt gattaagaaa aatgttagta caaatatgct
     1981 cttattaggt tgtattttgg cagggtttgt tttaagtata ataggtatct tataatgatt
     2041 aaggctctaa tttttgatat ggacggagtt ttaattgata gcgagattat gtatcaaaag
     2101 tgggtattta attttttaaa acaagaaaat ttaagctatc ctttgtattc ttatcaaaaa
     2161 aagattggaa ctacagcaag tatttttgat gatatagaaa agtacaatga gggatgtaac
     2221 agtttagaat tgaagggaaa atttactaaa tattggaaat cgcaaaagat tgattacttg
     2281 gatatttttc ctaatatact aattgaacag cttgaatggt taaaaaagaa aaaaataaaa
     2341 atggcaattg cttcttccag tccaatggat actataaatg aagttgttac cacttgtaaa
     2401 atagagtcat attttgattg tttaattagc ggaagagatt tgccagaaag taaacctaat
     2461 cctactatat tccttaaagc ttcagaacag ctcagaattc cagttgaaga atgtctggtg
     2521 atagaagatt cttataatgg tataaaagct ggtaaaagag caaatatgaa ggttcttgca
     2581 attaaagata aacgtttttc tcaagatgta agtctagcag atgatgttat ttacgatatt
     2641 aaatatctgc gacaagaagt acaggtgaaa tttggaatat aaataagttt tttgatgtat
     2701 ttagagaata ttagtaaaaa taaaaatcat gcccaaatct aatcaaaatt gattgctttg
     2761 ggtatgattt cttttaatat caatctatta ctttaggatc tgaatcattt ttatgcaccg
     2821 tatctaaagt gatattttct gtgacttcaa taacataact aattctatca caacgaactg
     2881 tggattgaga ataatgaaat ggttgattat ttttatcttt gccaaccttt tctaaaataa
     2941 atagcggatc tcctactata cattgcaata agtcggaaag ctcaggtgtt gcagataaac
     3001 cgtttatttc cataatagag ctcgtagctt tgacatcata gtcatcttct agaagtttat
     3061 ataatgaagt atattggcta cctttttcaa ataaagttgg aaatttttct tctgatgcga
     3121 aaaaattatc aattcccatc ggggcaccgt cttcccacat taaacgttta atattgtaaa
     3181 ctctatcagt tacattgatt tgtaatttat tagctaaaaa ctcatcagcc tttataattt
     3241 tagaatgtaa aacagtatat ctaattttat gtcctcgggt agaaagagaa tcgctaaatc
     3301 catgaactcc agctaatttt aaactttctt ttttttgagt tacaaaggtc cctttccccc
     3361 ttaatcgttc aactgttcca ctttctgcta aaagtttaaa agcttttcga atggtaatct
     3421 tacttactcc ataaatttta cataattctt cttctgtagg taattgctct cctggaagat
     3481 attttttttc acgaatatcg ttacgtatag aagcttctac ttgtaaatat aatggtctat
     3541 tatcttgaaa attcatagta cactccctaa aaagttatac ttcattatat cacaatttat
     3601 taaaacgtcg attgtaaaat taagctagac aactaaaaag atcatttgtg ctacactcaa
     3661 aatagttccg accaaagaat taataaggag tgagtacaaa tgacttacac ccatcttaca
     3721 acagacgaac tagtaatcat agagtcttat ttcaatatcg agaaacctgt cgctcttgtc
     3781 gcacaaagtt taaatcgctc tagacaaacc atttataatg tttattcgtt tctcaaacaa
     3841 ggaaaaaaag tgctagatta ttaccgtcaa tacaaacaaa ataaatctcg ttgtggacga
     3901 cgttcaaccg ttttatctga tgaacaatca acatatgttc aagaaaaggt agctcaagga
     3961 tggtcacccg atgtgattat cggccgtggc gagtttccaa ttgattgttc tgttcgtaca
     4021 ctctatcgga tgtttaaaaa aggccttttt gacacacagt cgttacctat gaaggggaaa
     4081 cgtaaaccga ataatcatca agaaaagcgt ggaaaacagg cctttcgcag aacgattcat
     4141 gaacggaaca gtctctatcc acacctgact aaagaatttg gtcatctcga agtcgacacc
     4201 attgtgggag ttaaacacaa gagcgctgtt attacattgg ttgagtgttt atccaaggtt
     4261 attattactt tgaaaccgac aggcagacga gccgaagata tcgaaaacag gttaaatgat
     4321 tggttcaaat ccatgcctaa acacttgttt aaatccatga catttgattg tggaaaagaa
     4381 ttttccaact ggcgatctat aagtaactcg aacgatattg ccatcttttt cgcagatcca
     4441 ggaacacctt cgcaaagagg gctaaatgag cactcaaacg gcttgcttag acgagatggc
     4501 ttacctaaaa caatggactt tagggacacg gatgaaacct ttattcaatc cgttgcctcg
     4561 aaaagaaacc atattccaag aaaatcatta aattatcgaa caccattgga agtatttttg
     4621 agctgcatag ataaagacat attgtctagc ttaatttgac aaatcagata gtataaaatg
     4681 aatcaaattg aatatcaaat atatattata tccatgaagc ccaatcttct ttaatagaag
     4741 attgggctat ttttatggca aaggagggaa aagaaatgtt tcaaaataaa ggacaacgtt
     4801 atgtcacaaa gggagtaatg gacagtttgc cggtggaatt acaagcttta tgttggaatc
     4861 taatcgatca aaacgttcaa aagcaatttc atttagacta tcttcaaatc tttgaatttt
     4921 ctacggaaaa aggaaatcaa aagttggttc atcgtcaaga agaaccagaa gcaagaaaag
     4981 agtatctgat ttcacctaag cttcgtttga aatcagtgtc tcaaaaaata tgggtcattg
     5041 attcgggtga gtatcaaacg atgttattac cagaagaata ctgatatcta aaagaaagga
     5101 acgaaaggac ttgttagaaa cggctatcga agtactggaa aagtgtgcac agctagtcac
     5161 tactcctgaa gagtggggct atgaatccgt tacgatggaa aaagaggaaa ttgaaatggg
     5221 tatgcttcct gaagatgtta ctctaccacg tttagtgatg acacatcttt atatttattg
     5281 cgcaccagaa gatggaaaag actatgtagt ttatttcatt acagatatta ccagccagcg
     5341 agaatttgtt cgtgggttac tggtagaagg acgattggtt tggagtcaga ttggaggaac
     5401 gaatgaataa gatcgattat ttgagaatga ttgcgaaatg tttagaagat atccttacag
     5461 cgattcatca aattctgaag aaaaaaggag aaagaatatg aaatattttc aactagtatt
     5521 gacacttata acggcaatgg tgattgaatt gcttgaacaa aaattagcat aggagaaaaa
     5581 gagatgattg aaaaagaatt agtgaccaca caaacagaag tttggcgaga tcctcatcat
     5641 acccatcgct atgttttcaa acgacaatgg gcgatcaaag gaaaagaagc ggaagataaa
     5701 ttagcggtag tcattactat tcgtccaaca gatacagaac catttacgaa tgatttgagt
     5761 atgttattaa tcgaaaagaa tatccgacaa ttaggattta ctggttttat tgctgtgaat
     5821 cttttttcgt atacaaaagc gaaaagtcct cgggtatttc ctcgtggaaa tgatgaacaa
     5881 tctttggaaa tattaacaac tgttttcaca gaaaagaaaa tcaacaccat tatttttgct
     5941 tgtggttcga ttacagcgac gagtcaagtg gcttatgaac aagcgaagac catttacgat
     6001 caattgagtg cgaaacaaaa aaagatgacc aaagtattga taaatgcaga aggtaagtta
     6061 tcccacccac taagtattca tgttcgtaat gaatggcaat tggcagatag tcaattatta
     6121 tttcaagaaa aataacattt tattttctta tgttacttat aagtagtttt acatgctttt
     6181 tgactttaaa aatacatgtg atgatacatg ttatatgaat tatcaatgta cccagtaata
     6241 tgctattttc attatgtaaa aaataacagg gggtgtgtag atggagattg atgaaacttg
     6301 tttgagtaac tcttataaaa gtatgaatga cttttttgag gaaatggaac tggattcaga
     6361 attgctctat caattttatc ttgcttttcg agggcaacag atttcttttc caatgaaaat
     6421 gtacgatcgt gagttagtta gaaaaagaat cgaaaacatg atagaacagg aaaaaactgt
     6481 agatatccgt caattgacag aagtttatgg tttctctgca agatggattc aaaaagtaat
     6541 taaacaaaaa gaaaggagac gagtacatgg ctaagctgat tgtattaggt ggtttaattt
     6601 acggtggata ttggttatat aaatatatgc ttgcgcatcc gaatatagat aaaggaaaag
     6661 taattaagac agttggggta atcatagttg gactcatagc tctaactaag aaaaataata
     6721 ctaatagccc aaaaataatg agaacttatc gctgtagagg atgtggaagg gaaatttcta
     6781 ctagttttaa tccatctgaa agccctcaag gaagagatcg ttgtcatgct ggctatcgac
     6841 attcttggga aaggattaac taaatgaaca ccattgagat taattgactg ataaaataag
     6901 tacgcgaggg agaaattgaa agggggaaat aaaatgaaaa aatggttgtt attactaatt
     6961 ggaatgggga ttttattcac tggttgtaca tctgagaata cgaggactaa agagactgta
     7021 gaaactgata caacaattga ggctaaaaaa agtaaaacgc aatcaactga acaaactaca
     7081 acagaaatga aacaatctgt ggaagcaagt acaagtgaaa gttcaatcat tgaatcttct
     7141 tctgaagagg ttaaaaatac tttgtgggat agtgagaaat ctactcaact agcaattttt
     7201 gtcccacaat ggggaaagac attaggtcaa gaatataaaa gctacaatcc tcagaacaat
     7261 gtaagtctgt atggtacgcc tttaccaagt gcagttattg atggaaattg gaaaatggca
     7321 atcaatgaag caccagttac cgtacaatgg tcagaagatg gaactggtca tgcagatttc
     7381 aatttagtag cagtttattc tgatgtagaa actggagaat atttagggca gcatgtatat
     7441 ttctttggct ttcaaaatgg acaacctaaa gtttatttaa cgcaacaaaa tcaaggcaat
     7501 gataaaaact acatgtactt caatgaaact cagaaccaac agttaaaaca aggtttcatt
     7561 gatattgtga atggacaaac tcctcaaact ccagtagtag aagaatctac tcaacaagca
     7621 acaactacaa cgacacaatc tacaagtagc tcagcaattt caagttggga agctgctaaa
     7681 gaaactgtac taaataataa agctttatgg ttgtatgatt ctcctgataa aaatgcatca
     7741 aatactaatt taattagcac aaatgaatat atgaaagatc taatgcaaga tgaaaatgga
     7801 agctactatt caattaatat tgtaacggat gataatggaa atacaacaat ggctggtgga
     7861 aaacaattcc gtgtttatac agatggaaga atttctcaac gtattggaat gactaacaat
     7921 tttcaaatga ttaaataat
//
LOCUS       DADVXK010000113         7919 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.114, whole genome shotgun sequence.
ACCESSION   DADVXK010000113 DADVXK010000000
VERSION     DADVXK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.114"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1313)
                     /locus_tag="KB909_002466"
     CDS             complement(<1..1313)
                     /locus_tag="KB909_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838431.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFL"
     gene            complement(1433..2080)
                     /locus_tag="KB909_002467"
     CDS             complement(1433..2080)
                     /locus_tag="KB909_002467"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBB6838432.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(2164..3591)
                     /gene="uxaC"
                     /locus_tag="KB909_002468"
     CDS             complement(2164..3591)
                     /gene="uxaC"
                     /locus_tag="KB909_002468"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6838433.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(3665..4744)
                     /gene="uxuA"
                     /locus_tag="KB909_002469"
     CDS             complement(3665..4744)
                     /gene="uxuA"
                     /locus_tag="KB909_002469"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6838434.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(4747..6378)
                     /locus_tag="KB909_002470"
     CDS             complement(4747..6378)
                     /locus_tag="KB909_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6838435.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            6682..7353
                     /locus_tag="KB909_002471"
     CDS             6682..7353
                     /locus_tag="KB909_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6838436.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT         2592 a         1557 c         1061 g         2709 t
ORIGIN      
        1 aggaaaaata aaattaatcc tacaatcaga aaacaaattg atggaattaa tgttgaagcg
       61 ttatataact tttctaaaac atctcccgtt tgtacatttg ctaaagagtc atagcctata
      121 atagaaagag tccaacctcc gacgcctcca gctagagctt gacctatttt tctagcaaaa
      181 gaatataccg catatacggt cccatcttct ctttgatcag actttacttc ttgatcatca
      241 ataacatcag taatatttgc ccaaataaca gtattaaaca cacccaaacc catatagcca
      301 accgaactaa gaattaagaa tacatacata ttactagctt ttatcaaaaa taagatcaaa
      361 tatactattg ctgaaaagaa cattcctact gatgccagtt ctttttttcc atatttttta
      421 cttaaaaaca aagttaaagg cgaaacaact attaaaacca aaataggatt gataaaattc
      481 attaaaacta ttccctgtgc atcattatag taatcaggaa atacataatt attcatactc
      541 ataattaata attgagcaag gagtaagaaa atagccgcac caattataga aagtaatgcc
      601 ctatttttaa ctaacccttt taaagatttt aacaatgaaa ctttgtattg agattggtca
      661 attcttactc gttcagtagt tagtttataa catattaaat aacaaataag tgcacatatc
      721 gaaaatattc ccgcaacaat tgtaaaagtt gatccaccac gaactatttg agcgcctgaa
      781 tcatctcttg tataaataaa taatggtgtt aatacaccaa tgaccaaact tgctaaagta
      841 gctccaacat ttcggaatgt cgatagcatt gttctttctt ctgtaataga agtaatagct
      901 gatgccattg atccataagg aatatttata gatgtgtaaa aaatactccc ccataatata
      961 tacgtaacat acatgtatac taccttaacg ctcatagaag ctgaaatcat agaagtttga
     1021 tacattaaaa aacttgctaa agcgactgga ccactcattc ttaaaatcca cggtttaaac
     1081 ttaccctgct tagttgcttt cgatctatca acaatacgcc ccatagttac atcagtaact
     1141 gcatcgataa atcttgctac taaaaataat gttccaacgg cagctccgct tatccccaat
     1201 acttttgtat aaaagatcat taaaaaagaa ctagcaaaaa tgaaagtaaa atcgtttcca
     1261 aaatctccaa acatatatcc tattttgtct cttataccaa attttctttc catacaattc
     1321 tctcccttct gttgttaagc gttttcattc tgatgaaagt acgtactata ctctgaagcg
     1381 taaagagtca gtatttattt tttacatttc agagtattat ttgttttttc tcctaataat
     1441 tctttatctc ataaaactta tctatatatt tactagctac tcgacttact tcttcaaaat
     1501 cacctttttc aacagaagcc aataaattcc cacctacacc aactgcaaca actcctactt
     1561 caaaccaatc ttctaagttc tctatactta ctccgccagt aggcattata tttacgtgtg
     1621 gtaatggagc ttgataggct tttacaatgg atggaccaaa agcagaacct gggaatagtt
     1681 taatgatatc tacgccagca gtaagtgcct cctttatctc agtaattgtc atacaacctg
     1741 gtaaataagg aatttgatat aaattacaaa tctcagctgt ttgtcgatca aaagatggac
     1801 taacgatata ttctgcccca gccataattg cgatacgagc agtaaacgca tctaaaaccg
     1861 taccggctcc gattattaca tctttttgat cagcatattt tttagcaatt tctttgatta
     1921 tttcttcagc attaggaact gtaaaagtta gttcaatccc tttaattcca cccgcaataa
     1981 ttgaatttat tgctttaatg gcctcatcct tatttttccc acgtacaacc gcaatgactc
     2041 cagccgcttc taacttactt aaaatttcta cttttttcat atctatctcc ttcctttatg
     2101 gatacatact ttgtctagct gtactaactt acaaagaata aatttaagct tttatttcaa
     2161 gtattatttt ctacttccga tttcaaaaaa attaaaataa ttatacgcat tacgataaca
     2221 aatattctcc actatctgac taagatacat ttcatcatct ggaattcggc ctgctttaac
     2281 ccactcgctt agtaattgac ataatactcg acgaaaatac tcatggcgag gatagcttag
     2341 aaaacttcga gaatcagtca acatacctgt aaaattcgac aacaaacttt gttgtgccat
     2401 cgtagtcaac tgttgacgca ttccttcagc tgtatcattg aaccaccaag cacatcccaa
     2461 ttggattttt tgaatcatac ccccttggaa gctttgcatt gctgttgcta gtggaagcca
     2521 atcagttgga tttaatgaat ataaaattgt ttttggtaag cacccactct tttcagcggt
     2581 atcgaacaat gctacaacat tttgtgtcaa actagcttga tcccccatcg aatcaccacc
     2641 gacatctact ccaatttgtt cctttaatat acttgaatta tttcttaaag catttaaatg
     2701 catttgcatc gtccaaccat atcttgtata ctcagacatc aaatgtaatt gaatacctgt
     2761 aacaaattgt gcaatttctg ataaatggaa atccgttttt cctgctaaag cttttattaa
     2821 cagattgtcg agtatttttt catctgctat ttcataaaaa taagtattca aaccgtgatc
     2881 tgctaatcga cagccaattt gatgaaaatg atccactcgt tggctcaatg cttgcttcaa
     2941 cccattaaag tctttgattg gtatagccgc tgtttgacta agttttaaaa tatagttcga
     3001 aaagcctgat gatttgatac tccagacctt atctggacgg aaagtaggta ataccttgaa
     3061 agaattatcc tgtttagaaa gctcagtatg ataccacaag tcatctgtag gatcatccgt
     3121 tgtacagatg gctttcacat ccatcatctc caacaattct ttcgggcgat aggaatccgt
     3181 ttgaattttt tcgttagcac gtcgccaaat ttctggtgca ttcttctcag aaattgtcaa
     3241 atcaatatca aagtaacgtt gtaattccaa atgagaccat tcaaaaatag gattacctgg
     3301 cgccttctcc actgttttta caaaagctaa aaatttttca taatcatcac ctggaccact
     3361 gatcaactct tcttctatac cattagctcg catcaatcgc catttataat gatctccagc
     3421 tcctttatca tttaaccata cctgagtcaa attcttgtat tgcttatttt ctagcaaata
     3481 tgctgggtct aaatgacaat gatagtcgat aattggttgg tgttttgcaa atttatgaaa
     3541 aagtctttta gctatttcat tctctaataa aaagttctta tctaaaaaca tatttaaaca
     3601 ctcctttcct tccgttagtt tttagaagag aaaatttttc ctctaaataa actcccttat
     3661 ataattattt actcgccccc ttttcaagcg cttcccaaat accatttaaa taaactgcac
     3721 ctagagctcg gtcatataat ccataaccag gtctaccggt ttctccccaa atcatccgac
     3781 catgatctgg acgaatatag ccattaaatc cattatcgta cattgttttt aatatcttat
     3841 acatatctag agaaccatat tctgatttat gcggcgcttc gtaaaaatcg agtccattgt
     3901 cacttaaata tttgatatta cgaacatgtg caaaaggaat ccgatcccgt tgacaaaatt
     3961 cagatagaat ttcatagaca tcattatctg gtcgttctgc aatacttcca gtacataatg
     4021 taataccatt agaaggagaa tccactacat tacacaacca atctaaatcg tcacgatttt
     4081 taacaatacg aggtaatccg aaaatggaat atggtggatc atctgggtga actgccattt
     4141 taatcccaac ttcttcacat gtcgggataa ttgctttgag aaaatatgca aagttctctc
     4201 gtaatttctc ttcatcaact tctttatagg cttctaataa ttgcttaatt tgtgataacc
     4261 gatgaggttc ccaacccggc aattcaaaat tattagtaga attttctact tctctaataa
     4321 tttcctccgg atcagtaggg atattttttg aaatataggc taacgtagaa gacccatcat
     4381 ctaaacgata atccaaatcc gattttaccc aatcaaatac tggcataaaa ttataacaga
     4441 taacctcaat cccaaattct gccaaattgc gaatcgtctg tttataattc tcaatgtatt
     4501 gatctcgtgt tggtaaacca attttgatat catcatgaac attaacactc tcaataactt
     4561 tcaaggtaag tccattggct tcgacttcat cttttaaaga tttaattcgt tctctcggcc
     4621 aaacctctcc ggctggtata tccattaatg ttccaacaat tcctttcatt gctgggatct
     4681 gacgaatttc ttgtagtgag attttttctt catttgcccc ataccatcta aaagtcattt
     4741 ccatagttac tttcctccaa cttctgttat atatttattg attgttttac gaactgcttg
     4801 aggacctact agcatttcgc aaaagatttt ttcagttttc tttcctaccc caacttgata
     4861 taaatctaaa ccaaagattt ctttattttc taaaatttcc tgtaccgcac aatgaatctt
     4921 tgaaggatct tgttcaccta atttcaatac tgataattta tcctgcaact ctaccaataa
     4981 cggatcagga cttggcacaa aattttcccc ttgatcatcg actgccagta aataacgtaa
     5041 ccaagcagca atagcgatag gaataaatgt tagattttct gcatttccgt ctttttcgac
     5101 atacttttta attgtttcac catagcgaat cgctactttt tgagaagtat ctgttgcaat
     5161 tcgttgtggt gtatctggaa tatagggatt aggcaaacgt ttattaatta cttcatcaat
     5221 aaattgtttt ggatcaataa tgcctggatt ttcaactact ggtaaacctt ctaaataacc
     5281 tattcctttg attaaaccaa ccaaatcatc atcctgcatc tctgctgaaa ttgattgata
     5341 tcctagcaga caacctgtta ctgccaaagc agtatgaagt ggattcaagc ttgtcgtaac
     5401 cttcatgatg tctgctttat caaccgtctc tctatctgtc ataatcacac cagccttttc
     5461 caatttaggc cggccatttg gaaaactatc ttcaataact aaataatgaa ctacctcagt
     5521 attagtgaaa gcagcaatat tggtatgttt ttttgtgtga atgatatcta aatcctcgag
     5581 ccccatcatc aatagatctt cctttacatt ctctgaagga tttggcgtaa ttcgatcaat
     5641 catactccaa ggaaaagtca ctttttcttt atcctttaaa taagcaataa atttttcaga
     5701 aacatatcct tctttttgcc aagcttctgc aatcgtaaaa atactatctt gaaaacgttg
     5761 accattctgt gagaaattat cagtagaaac catcgcaatc ggcaactctc cagcattaaa
     5821 tctgctatat aacaaggatg ttacaatact catcgtatgt tgaggattgc taggtccaga
     5881 tttgatatca gctttgacta ccgaaaagaa ttgcccttta gaatctttta aactgtaacc
     5941 tttttcagta atagtaaacg ttgtaaactg taatttagga tcttcaaaat atttaaccac
     6001 tctttgatag tccgctatat tcttcggatt gcaatataaa ctatcagccg ttactgccaa
     6061 aagtcttttt ttgagttcac catctccact cataacaatt tccaaaatgt cattgttata
     6121 gtcatgataa gctttttcca ctacttcttc atcaaatgtt tcacacacaa ctactcctgt
     6181 ttctaattca ttttgatctg ctaagcattg agcaatttct gcatgaaatc ctcgataaag
     6241 atttcctcca ccaaaatgaa gccatactgg atgttgctgg ccttcttgct taacttcttt
     6301 gacatcaaaa cacggcagta gaatctgcat ttcattgaat tcttcgatag aattttgcca
     6361 atttttaatc gaaaccataa ttaacctcct caaactgata tgttagtttt gatacatttt
     6421 atattttaaa acccattgta accgttgtca atataaaaag ggaataaact tgcttttttc
     6481 taccatatca gaatgattgt attttttatt cagaaaaata aaatactcct tctttttgga
     6541 ctgattttat cgaaacttat tttttctttt tttcatgtat tcttttattt ttataactag
     6601 tgtattactt caaaatttga tattatatgg catgaacaga attaaaatat cagttaaaat
     6661 aaaagttaag gagcattgtg tatgacaatt aaaactagtc tccaaaatca agcttaccaa
     6721 tctattcgcc gacaaattat ctatgctgac ttagaacctg gaaaaaaagt atcagaaaaa
     6781 aaattagaag aaacactttc tattggtcgt acaccaatac gtgaagcact gattcaactc
     6841 cgacaacaag gtcttgttga tacaattcct caaagcggaa attatatctc attaattgat
     6901 ttagattcgg ccaaaaatgc tcgatttgtc agagaacatt tggaacgaca aattatgtta
     6961 gagtgttgtg ccaaaatgaa taaccaaaaa aaacggattt tagaaactat aatttcagaa
     7021 caagaaaaag ctgttagtca aaaaaatgct cgtagttttt ttcataatga taatttattc
     7081 cataaagctt gttttgaaat tgcagagcga gaagaagtat ggcaatggtt agaaaataac
     7141 aatacacact tagaacgatt tcgatggcta cgagtaaaaa cggaaggatt aaagtgggaa
     7201 aaaattatgg aacaacatta tcaactattt gaggcattaa caaaacaaga tccagaagaa
     7261 gctaactttc taacatcgtt gcatcttcat ttaatgctta atgagcaaaa tattgtttta
     7321 gctactcatc caaaatattt caaaaatata taacttttaa ctctttttaa attaaatggt
     7381 tgttctgatc agaaaaatat cgcttgtttt cttattatgt aatatatttc ataaactatt
     7441 ctgcataaca actattgttt gtacttttta cattggataa ctaattatga ctgctgataa
     7501 cttttgatat taaactagta tctccaatac aaataaaaaa tagatatctt gttcatcaaa
     7561 attagttcgt ggatacttac cttcatttac atcattcagc ggtttcccat tttcttttat
     7621 tctattattt cattttctaa tagacttggc ttcatttcgc aatacttttt ttcaataggc
     7681 atcaaattgg tgttgtttag atatttagtt gtagttttgt gacatgataa gtatgctcct
     7741 ttttctcttt tccactaata caacgatcaa agggtgcttt tttcaaaaaa ctagaaaaat
     7801 caaaataaga ttcgtatttt gattctatat atcctgtttc aactacatct tatatttcac
     7861 aatagaataa atagcctttt gcatagctgc ttaacttata agaaattgca atttacttc
//
LOCUS       DADVXK010000114         7678 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.116, whole genome shotgun sequence.
ACCESSION   DADVXK010000114 DADVXK010000000
VERSION     DADVXK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.116"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            17..2344
                     /locus_tag="KB909_002472"
     CDS             17..2344
                     /locus_tag="KB909_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6838437.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2470..2799
                     /locus_tag="KB909_002473"
     CDS             2470..2799
                     /locus_tag="KB909_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6838438.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2839..3843
                     /locus_tag="KB909_002474"
     CDS             2839..3843
                     /locus_tag="KB909_002474"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6838439.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3840..4286
                     /locus_tag="KB909_002475"
     CDS             3840..4286
                     /locus_tag="KB909_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6838440.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4436..5251
                     /locus_tag="KB909_002476"
     CDS             4436..5251
                     /locus_tag="KB909_002476"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6838441.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5457..6629
                     /locus_tag="KB909_002477"
     CDS             5457..6629
                     /locus_tag="KB909_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6838442.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6839..7324)
                     /locus_tag="KB909_002478"
     CDS             complement(6839..7324)
                     /locus_tag="KB909_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838443.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQEAI
                     AQQQAEQARQQSAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATL
                     S"
     gene            complement(7321..7515)
                     /locus_tag="KB909_002479"
     CDS             complement(7321..7515)
                     /locus_tag="KB909_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838444.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
BASE COUNT         2573 a         1454 c         1533 g         2118 t
ORIGIN      
        1 tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc aacgtatatg
       61 tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact tacatcccat
      121 tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta tttatgtaaa
      181 cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa atagtccacc
      241 ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg agacaacctc
      301 aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag cagcaaaagc
      361 agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta ctgttgcggc
      421 cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat atgccaaaga
      481 tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt tacaaggcgt
      541 aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt ttattggctc
      601 cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg tggctaccgc
      661 tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt ttacaccctc
      721 aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg gtatacagtt
      781 agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg ttgatggtaa
      841 gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca atgcgaatcg
      901 gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa cgtacgggac
      961 tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag cagtaacggg
     1021 ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg tcgatacggt
     1081 gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt ttggacagat
     1141 gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag acctgacgac
     1201 taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgatag aaacaaagaa
     1261 ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa tcgtaaagga
     1321 cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg caacagtatc
     1381 aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga tcgttaaata
     1441 tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca gtattgatca
     1501 aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg aagtaactgc
     1561 gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac tagctaaact
     1621 agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct atacgattaa
     1681 gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa aagcaggtgt
     1741 cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc cagtacaagt
     1801 ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata tggttaatgc
     1861 tggcagctat acaattaaac taacgaatag cggaatagac aaagtcaaag cagcaaatcc
     1921 caagttgtca tttactgata tagccaacac atcaggaact tataccatct ataaagctaa
     1981 cgcagtgatt actgtcgatg acgctgcctt taattatgat gcccaaagtc actcgatttc
     2041 ggttggaaat ctccacgtta ccggtgttgt cttaggcgaa tcattggatt ataccctaac
     2101 agttaacagc cggacagata ttggatcaca aatagtaacg attagtttag gcgaaggaag
     2161 tgtaaacaat aattatacga ttatcgcaac agataccgct aagttgacga tcaatccgac
     2221 tctcttgctt ccttcgacag gtgggatagg tctactgccc tttgtctttt taggactgat
     2281 ctttattttt tctggcttct tttattttat ccatcgtaag aaaaaagcag gtgaacagcg
     2341 atgaaaaaaa caaaaaatgt acgtgtggat atatttgctg ttctcttttt tatcctactg
     2401 gtctttttta taggttctcc gactgtgtca gctagagaat cacctattac atttactttg
     2461 cataatcgaa tgttcgaaag cgataagatg ccaagtatca gtcaaaacga cggaataaat
     2521 atcccggata actttcaagg agtaaaaggg ttgaacggcg ttactttcgc tatatatgat
     2581 gtctcggatg aattttacaa gctgcggtca gaaggaagta gtgtggaaga cgcacaaaga
     2641 aaactagcac aaaaaagtga tagtgaaaaa atactggcag aaaatgtgac aaaaacagta
     2701 gacgaggaag agggcattgc ttcttttagt gcatcggaca aagatgagca aggtcgtgac
     2761 gctgtttacc gatttacgga aataaagact tcagattaag taaaagaaaa atcagcacca
     2821 tttgtcgttg tgcttcctgt gacagattca tctaatcata aattgacgac catccacttg
     2881 tatccaaaga gcgaacaaaa aatacctgct gcactcacat taacaaaaac agtagagaat
     2941 aagcagacag attttgcaga tggggataaa gtcccttatc tcatcaccgt aacaattcct
     3001 gagaacatca acgagatagg aacctatacg atcaaagata cagctgatcc tcagttatgg
     3061 ctagaaccag aaacgatcga ttttttgatt ggtggagaca agattcatac atttcacaca
     3121 caaaaaataa aacatggttt tgtcttatca gattctggaa aagatcttag ttcgtttgct
     3181 ggaaaaaaat taacgatccg ttaccaaatg acattgaaag aaaacagtga aaaaacgaca
     3241 tttgataacg atgtacgttt gacgactgac aatcaaacag tagaaacaca tcttgccatc
     3301 caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa cgaaacaaaa actagcagat
     3361 gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc aagaaaacgg gataaatcat
     3421 tgggtagcca aagatgattc aagagcaacg atttttactt ccagtaaaga tggaacattt
     3481 tctgtccatg gattgtcttt tggaagttac gaactagtgg agattaaacc gcctaaagga
     3541 tatatattga gtcaatcaac cattctcttt gaagttgaaa aaggcagtta tgatccgctt
     3601 catcctatac cattggaaat catcaacgaa ccaaaagcaa atccgacgaa taatggaaaa
     3661 acgccagttc agatgcagac aaatggtcca tcaaatgaaa aaaatggagg aagctttcca
     3721 aaaacaagcg aagagatgct tggaggtttc tcaattttag ggttattgct agtcctttca
     3781 acagggacag cttggtttta taaaaaacaa caaaaaggaa acaataggag ggaaataaaa
     3841 tgaaaaacat caaaacaaaa atatggacgt ttttaggaac tgctatcatg ctgcttcctt
     3901 tcgttctcgg cctaggaact gcagaggttt ctgcagccgt atcacctaca ccagaaaatg
     3961 ttacggttaa tttgcataaa ttgaaattca cttcagcacc agaaaatcaa ataaacaacg
     4021 gaacggaatt gacatttccg aatagcgaac cgttgaacgg cgttgaattc aacgtatatg
     4081 acatcactgc tacgtactat ccaagtaaag acacagcagt tccagcagac gctacaccct
     4141 tcgcaagtgt aacgacttct ggtgaaggat tagctaacct gactcttcca ggtaaatctg
     4201 atgggaaaga tgctgtatac gtctttgtag aaacaccaaa gcccggtgtc gaaacgtcgc
     4261 caaatatcgt gttaagctta ccctagaccc tgacaaacct ttagacacga ttcacctata
     4321 tgctaaaaat gtcatcaaag aaagcaatat caaaatccag aaagctggga acttttcagg
     4381 ggtagataag ttagcagggg cgcaattcca gatcaaaaat tcagagaatc aattcgtgac
     4441 cggttttgat gaaaacactg gtgtcgctct ctatgatcct gctgagtcag cgttgacatt
     4501 cacaactgat actgaaggat ccatcagtgt caatggatta atagacggca attatacttt
     4561 agttgaaaca aaagcaccag atggttatca attaaccaat ccacaaaaag aaactacttt
     4621 tatagtaaaa aacggaaaat tgcaacaaac aaccggtatc atccatggcg cagatgaagc
     4681 caatcttggg aatccaaacg gtgtagtcaa tcgggaaaat acaactacgg ataacacgat
     4741 tactgtagaa aatgtccaaa actacggtga tttccacttc atcaaacaag atgtgaacac
     4801 gcaagaaaaa ttagccgatg cagaattttc tattctaaga gcaaaagatc caactgttaa
     4861 attaatgaaa aaaatagcaa accttgcctc aggagaatac ccatatgctt ggtcagatga
     4921 agtcacaggt tctgactggg aagaagtgaa attgatttct gattcagaag ggaaattttc
     4981 aatcgaaggg ctgaaacaag gggcatactg ccttcaagaa acaaaagcac cagaaggcta
     5041 cgcattacct aagaatgaag ctgcgtacac tgaatttaca gtagatgatg atccaacaac
     5101 ttctgatgaa acaacgatcg ataaccaacc taaaggaatc ttgccttcaa ctggtggtat
     5161 ggggatcatc gtattcatct tggtaggtac tgctttagtt ggaggagcag tgatctattt
     5221 caaaaaacgc catcaagaaa cagaagctta aactattgga aacaaaaatc atacgataaa
     5281 taaacgatag tgattcaaat ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt
     5341 cgctcaacaa acggcaaaat aggaggaact attttgccgt ttgcttcgct aatactcagg
     5401 tcaaggcgct gatttcacaa cctcttcata tacatattag aaaataggtg gacatgatga
     5461 ataaaagcag aataagaata ctggacatct tcatggcaat cattttagtc gttgggatcg
     5521 ggatcttttc ttatcctttt gtagaagatt cactgaatga ttttcttgcc cagcaaatga
     5581 tcatccatta tcaaaagcaa gcatcgaata agaattcaga ggaaataaaa aaacagcagg
     5641 aaaaaatgac aaagaaaaac caacagttgg cagagcaaaa cgtatcacca gggataggca
     5701 gtttcaacca agcagttgat gcaaaagcat taaaagattt acctagtaat gcctttttta
     5761 tggaacatat gcttggagtc atcgaaatcc caaaaatcaa tgtcagctta cctatattcg
     5821 atcagacaac ggaaatattt ttgcaaaaag gaacgtcatt attggaagaa agttcttatc
     5881 cgactggcgg gaaaaacacc catgccgttc tttctgggca tcgtggactc ccagaagcaa
     5941 aattatttac agatttgcct aagttgaaaa aaggagacca gtttttcatc cagatcaatg
     6001 gaaagacatt ggcgtatcaa gtagaaaaaa tccaagtggt cttacctgat gaagtagatt
     6061 ctttgggtat ccaaaaaggc agagatctcg tgactttgct tacctgtact ccttatatgg
     6121 tcaatacaca tcgactgctt gtgacggggc atcgtattcc ttatcaagca aaagaggcaa
     6181 aaaaagcgat ccaaggaatt gatcaatgga aaaaatggaa attttttatt tggtttatcg
     6241 gtatactact tggatcaatc ggcttagttt ggctactcat cgcttattta gattctttgg
     6301 ccatcgctaa gcgaaactat cctttatctt tttatgtaaa gaacacaaac ggacgaccaa
     6361 tcgaaggaat ggtcttttct gtaaaaacgc tcaacggcaa acactatatt actagagaaa
     6421 aagttccatt tgtgaaagct tctgatgaat acggactagt gagattttct gatttaaaag
     6481 gcaggaacta tcgcttgcaa catgaggagc tcctgcttaa aatccatgta aaacataaac
     6541 attcgaaaca gttttcaatg aaattgaaaa aaggaagata taaactgcga aaagaaaaag
     6601 aggtgtacta tttgattgag aaagaatgaa tgaagatgtc caaaaaagca gagggaacag
     6661 actaaatgaa aaaagagaga agctgacgaa atggacgtgt aaactgttat ttttggttta
     6721 ctatctggaa cgccatcttc tattttttta tgtttcagaa gaattttatt attatagtat
     6781 aacttttgaa ttagtttcca taacatttgg agcaaggggt taaaccacga gcttgagctt
     6841 agcttaaagt ggcaggggta tacgtaccat ttccacattt atgtgtatgg tattttgaac
     6901 cggtcggtgt gacatagaca gtttgttcat tattttgctc aggagctgcg gcttgtgcct
     6961 gctgagaggc ctgttcagct gctgattgct gtcgcgcctg ttctgcttgt tgctgtgcga
     7021 ttgcttcttg cctcgcctgt tctgcttgtt gctgtgcgat tgcttcttgc ctcgcctgtt
     7081 ctgcttgttg ctgtgcgatt gcttcttgtt gcgcttgttc tgcttgttgt cgtgcaattt
     7141 cttcttgctt tttccgttct tcttctgctt cttttgcttt gattgtggaa tcaattgcag
     7201 caagacggct tgtcaactct tgtttgtttt caggtagcgc ttggatagct gctgaagcag
     7261 ttgcatagtt ttcttttgta ggatttgctt cagcttgtga caaagcagat tccgcttctg
     7321 tcactttttt tctagtgcag ctttttccgc tttttgtttc tcttcttttt tcttttcaat
     7381 ttgttcttgt tctttcgatg aatctgccgt actttcggag atcgtggtac tgctgctgga
     7441 agcctgatct gaacttgtgc tttgagtagt agacgtagta gcaccacacc cactcaacaa
     7501 acttcctgcg accaaaaaca atgcaactaa ttttttcgct aaatttcctc cttaagtaaa
     7561 aaacaaccgt tttcaataaa tgtccttttc aattgtttac ttacttgtta taataattgt
     7621 gttatgaata gtgattgagg aaacttaatc taatcccgtg ttgatacacg ggattttt
//
LOCUS       DADVXK010000115         7600 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.117, whole genome shotgun sequence.
ACCESSION   DADVXK010000115 DADVXK010000000
VERSION     DADVXK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.117"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(943..1356)
                     /locus_tag="KB909_002480"
     CDS             complement(943..1356)
                     /locus_tag="KB909_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBB6838445.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="KB909_002481"
     CDS             complement(1812..2297)
                     /locus_tag="KB909_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838446.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="KB909_002482"
     CDS             complement(2436..2651)
                     /locus_tag="KB909_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBB6838447.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="KB909_002483"
     CDS             2875..3675
                     /locus_tag="KB909_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6838448.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="KB909_002484"
     CDS             3694..5562
                     /locus_tag="KB909_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6838449.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="KB909_002485"
     CDS             5555..6046
                     /locus_tag="KB909_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBB6838450.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="KB909_002486"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="KB909_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBB6838451.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="KB909_002487"
     CDS             6606..>7600
                     /locus_tag="KB909_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBB6838452.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DADVXK010000116         7511 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.118, whole genome shotgun sequence.
ACCESSION   DADVXK010000116 DADVXK010000000
VERSION     DADVXK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.118"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(324..1772)
                     /gene="cls"
                     /locus_tag="KB909_002488"
     CDS             complement(324..1772)
                     /gene="cls"
                     /locus_tag="KB909_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6838453.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1924..2817)
                     /locus_tag="KB909_002489"
     CDS             complement(1924..2817)
                     /locus_tag="KB909_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838454.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2801..3487)
                     /gene="ftsE"
                     /locus_tag="KB909_002490"
     CDS             complement(2801..3487)
                     /gene="ftsE"
                     /locus_tag="KB909_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBB6838455.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3592..4693)
                     /gene="prfB"
                     /locus_tag="KB909_002491"
     CDS             complement(join(3592..4620,4622..4693))
                     /gene="prfB"
                     /locus_tag="KB909_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBB6838456.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4819..7353)
                     /gene="secA"
                     /locus_tag="KB909_002492"
     CDS             complement(4819..7353)
                     /gene="secA"
                     /locus_tag="KB909_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBB6838457.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         2007 a         1658 c         1306 g         2540 t
ORIGIN      
        1 aaatcattca tagggaagtc ctcttttctg tgaattggtt gtcgttaact ttattctaca
       61 gaagggactt ccttttttgt atggattttt tcatttacac aaaatatttt atactctcat
      121 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
      181 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      241 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      301 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      361 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      421 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      481 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      541 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      601 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      661 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      721 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      781 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      841 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      901 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      961 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
     1021 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
     1081 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1141 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1201 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1261 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1321 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1381 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1441 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1501 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1561 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1621 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1681 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1741 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1801 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1861 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1921 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1981 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     2041 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     2101 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2161 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2221 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2281 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2341 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2401 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2461 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2521 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2581 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2641 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2701 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2761 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2821 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2881 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2941 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     3001 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     3061 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3121 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3181 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3241 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3301 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3361 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3421 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3481 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3541 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3601 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3661 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3721 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3781 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3841 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3901 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3961 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     4021 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     4081 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4141 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4201 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4261 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4321 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4381 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4441 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4501 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4561 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4621 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4681 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4741 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4801 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4861 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4921 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4981 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     5041 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     5101 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5161 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5221 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5281 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5341 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5401 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5461 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5521 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5581 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5641 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5701 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5761 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5821 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5881 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5941 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     6001 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     6061 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6121 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6181 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6241 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6301 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6361 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6421 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6481 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6541 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6601 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6661 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6721 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6781 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6841 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6901 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6961 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     7021 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     7081 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7141 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7201 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7261 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7321 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7381 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7441 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7501 gaggaaactc a
//
LOCUS       DADVXK010000117         7117 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.119, whole genome shotgun sequence.
ACCESSION   DADVXK010000117 DADVXK010000000
VERSION     DADVXK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.119"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..563)
                     /locus_tag="KB909_002493"
     CDS             complement(<1..563)
                     /locus_tag="KB909_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBB6838458.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="KB909_002494"
     CDS             complement(750..1400)
                     /locus_tag="KB909_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838459.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="KB909_002495"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="KB909_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBB6838460.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /locus_tag="KB909_002496"
     CDS             complement(2912..3910)
                     /locus_tag="KB909_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBB6838461.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="KB909_002497"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="KB909_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBB6838462.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="KB909_002498"
     CDS             complement(4926..5657)
                     /locus_tag="KB909_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBB6838463.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="KB909_002499"
     CDS             complement(5661..6926)
                     /locus_tag="KB909_002499"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBB6838464.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
BASE COUNT         2146 a         1511 c         1102 g         2358 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaac
//
LOCUS       DADVXK010000118         7081 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.120, whole genome shotgun sequence.
ACCESSION   DADVXK010000118 DADVXK010000000
VERSION     DADVXK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.120"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..436)
                     /locus_tag="KB909_002500"
     CDS             complement(<1..436)
                     /locus_tag="KB909_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838465.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLN"
     gene            complement(590..916)
                     /locus_tag="KB909_002501"
     CDS             complement(590..916)
                     /locus_tag="KB909_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838466.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(953..1318)
                     /locus_tag="KB909_002502"
     CDS             complement(953..1318)
                     /locus_tag="KB909_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBB6838467.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(1355..1570)
                     /locus_tag="KB909_002503"
     CDS             complement(1355..1570)
                     /locus_tag="KB909_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838468.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            1699..2034
                     /locus_tag="KB909_002504"
     CDS             1699..2034
                     /locus_tag="KB909_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838469.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(2110..4107)
                     /locus_tag="KB909_002505"
     CDS             complement(2110..4107)
                     /locus_tag="KB909_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838470.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(4205..4480)
                     /locus_tag="KB909_002506"
     CDS             complement(4205..4480)
                     /locus_tag="KB909_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838471.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            4712..5446
                     /locus_tag="KB909_002507"
     CDS             4712..5446
                     /locus_tag="KB909_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838472.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            5485..6627
                     /locus_tag="KB909_002508"
     CDS             5485..6627
                     /locus_tag="KB909_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838473.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         2386 a         1295 c         1021 g         2379 t
ORIGIN      
        1 cattaagtga cttctctttt atatttccat ctaaaaactc tgtatatatg gcttgagcta
       61 tactaaaaca aagctggcct tgttctaata attttacatc attagttagt aaagctgtgt
      121 tcacgttatc aatcgcttca agaagagtat ctttggtgtc cctaacagct ttaggtgtgc
      181 cttctggaat ttccctactt gatacctcgt ccattttatc ttccataaac cccttaaaat
      241 catatctttc tcccaaatcc atagaagttt ttgagaaagc tttcatttct gagtctattt
      301 cttcaataat atttaacatg tctgatacat attgtttagg ctgattcgtt tttaatctat
      361 atgtggtaaa tatctcaatt cctccaatta tcaataaaat tgccaaacaa atccataata
      421 attttttctt tttcattttt cctcctatac actgctgtta taacagtgac taatgtaaag
      481 attttcccag caatcatcag actattattt acagggaatc aaaaaaactc cttagtaagc
      541 ttacaccttt aggagttcct gtttgaacgg tatgcataat acatttaaat caatttaaca
      601 ttaacacctc agtatatggt atctctacat atacacggtc tttttttgga tagtactcga
      661 catttatatt gatagcactt ccattgtcta acgtagcttt agcccggtac gtgttatcac
      721 cattatcatg agtgatcgtc acatcatcac atgtccgatt taagttatac tgttcttgta
      781 aaatctgagt taccaatggt acagatgact tctctagtcc agatgaaccc gtcattcttg
      841 aaaaaattat acctataata gccaatacaa cgatacctat aatgacaaac ttcttattca
      901 tatttacttt attcaacttt ttatctccta tctccaaaat gattttctct catcagtaac
      961 tcattgacat ccccaatagt acaccaaaga tggctccagc tacccctgct atcatcaaaa
     1021 tcgtacccat ttgttcatct ttctctcgat ataagtaacc cataataaca gcaacagcac
     1081 caaataccac aggaataaat gctaatgata ctaccataga aatccaacca ataatcaaat
     1141 acagcttccc tgtctcttgt ccatgtacga tttgttcctt catttcatta attgtctgct
     1201 cagtactttt ctttactgtg tctgttccgg ttgtctcatc tgtttcttgt aatgctccgc
     1261 aaaactggca atacttactt tcatttgtta tttctttacc acattttcta caatacatgt
     1321 cttctcctcc taaaatcatt caattgctta ttagctaact gtttacttta ttaaatacat
     1381 cagaaaacag ctcatttatt ggtacactta atatctcaga aagcattttc atttgatagg
     1441 gtttaggaat cgttctccct gtttgccacg aacttacaca ttgctgtgta acattcattt
     1501 ttttggctaa ctcagtttgg gaaagtcctt tttcttttct gtatcggctg agattactta
     1561 cttttttcat gattctcccc tcctgtttta ttatatacaa caatatgatg tatttcaact
     1621 cataaaatat ataaatactt caaatgtcat tacaaataca acaacttgtt gtactctact
     1681 gagaaggggg gtgtattaat gaaacagaag caatatgcaa aggtcattag agaaaagcga
     1741 aaagcactcg ggtggacaca aaaagaatta gctaaaaaaa tcttctctac acaacaggca
     1801 gtagcaagat gggaaaattc tgtaacagaa cctaacctcg atagcttaac agctctttct
     1861 agagccctag gaacccctgt aagccatttt ctagacaatg ttgacataga ttatgaggaa
     1921 gagtttttgg ctctctatcg ctctcttagt actgaagatg caattcgaac aattgactat
     1981 atgaagctat taaaaaggca agaaaatgaa cgcaatcagc tattgaaaga ttgaaaaata
     2041 aataacccac cgaactttaa cggtgggtgt attgagatga aataagatta agagctatgg
     2101 ataacctgtc tagtttaata taattgggtc tcttctattc cttactctcc gtccatcatc
     2161 tcttgttaca cttgtaaatt gataaatagg aactaattca actcctgata atatcaattc
     2221 ttttattact tcatctatcc ctgccccttt cgctagatat actaaaaaac tactgcttgc
     2281 tttcacattg tatagtttct taatatcctt agaagctcgt tcaagagtga atccttgttt
     2341 aacaaagtag cctctgtttt ctattaaagc atttttcacg ctgttatccc tgacatttcg
     2401 taggcgttca caaacagtgt taataagttc tttttctgtc attagatatg tcccttgcca
     2461 cgataagccc tgtaaaactt catgtgcttc atctaaaatc aattgttttt ccttgctaag
     2521 ttctgatcgg gaattttgag gaaatactct tttagcctct ttttcgttaa aacatatctt
     2581 aacccattca taagaaaaat attgatatgt aaaatgaaat ttttccagaa gtggaaggat
     2641 atcttcattc aatttttgaa tcacagaagt tgcattaaaa acgtctaatc gatagacatt
     2701 gcttctctta tgtttaaagt ttcctaacgc tttctcttcc tttaacctat ttaggtattc
     2761 gagcatcttc aaaggaacat cttcatcatc taattttttt atcaatccta taaaagtcat
     2821 aagtgatagt aacttattac atttatctat gtcataagtt ttaccatagt aagaactcat
     2881 ttttttagct aattgttccc ccgacaaaat acaagtcaca ctttccttac tatcatcaaa
     2941 aaaattaaca tcagaaagca agacatcata gacacgtcgc atttcctcta gataattcct
     3001 tattgtcctg aaaagtttgt ctttcattga ttcaagagtg tcaaaaagta cttttgattc
     3061 ctctttcaat tttcgaaaat gtgtaggata caagtctagg ttctctaata gccaattaaa
     3121 tgtttctacc cgactgtctt tctttaaaat tagcatcaca actccaataa aattttcact
     3181 gatatcacaa ttactggaat gacaataaaa aatggaatgc ccagttttac tggtaaaaat
     3241 actagcagag ggattatgat cgttgtgaaa cagacatctt aagtttttac ttgacttaag
     3301 taatttattc atatcaatgg ttaacaatct ttcataaatc tcattaaaag acatgtcgga
     3361 ggaatcaaac aggcagtctt taaaccactg tttcatttct tctttgtcgt cattttttat
     3421 caacttaaca aaatcggttt cattgactag ttcatactct ctccctgaat cactttgaca
     3481 atttttagaa catgtcatgg taaaatcaat cggaagctca gtaatatcta acatgttgtc
     3541 ttcattaatt attatcactg catctgactt atatcctcca aaaaacattc tattcgaagc
     3601 atttacattg tcatcacacc cggggatgtt ctttttcaag tattcgtaaa cagcaaccat
     3661 tttaccatag tcagtaattg cttcttttaa tagaaagaca atcttgtatt tttctagatt
     3721 ttcagagtac cgaatacttt tttgtatcgc aaacgcagaa ttatgaacta aattgataga
     3781 taaaaccttt tctatgctta agtatctact atcatcttta ctcaaatcta ctaccttccc
     3841 cttctcatct ttaacagtgt tatcgacatc cagaataatt actctggttt ccacaaaact
     3901 ctccttgtca ttgcctttat tctttgtctt gcttggaata aatgattgtg atgaatttag
     3961 tatctctaca aactcatctc ttgtaacttc tctatagtta tctaaacacc tatctcttac
     4021 atcagttttt tctttttttg taactggctt ctctaataat ttttctttat ctacataaat
     4081 tggaatatta atcattgatg tttccatttg tgtttcctcc ttataaaatt ctgttaaaga
     4141 ctaaaacata cagataataa aaacaaactc tttattacta tatgttttag tcttatttgt
     4201 ttactcaacc tttataccgt tccatgaaac tatcaatatc agatttttta aatctaatga
     4261 ccgtatcaat ttttataaca ggtaacccgt attgagaaac atattttcta atcgttccta
     4321 ctgatacacc tagatattca cttgcctgct gatagtccat atactctaga gtgactccag
     4381 aaataatgtc ttctagcata ggctttagca ctgtaattat ctctttcact tgttgttcaa
     4441 cttgtataga aacaatgcta tcaatgattt gtagagacat atttccccct cctttcgtga
     4501 ttgcttgaac aaattttcta agaattatct tcgtattttt tgctcaaaat aaaagtattt
     4561 tgttattaac cgattaatca aacaaaaaat gattaccagt tcatcgacat acacataata
     4621 cctcgataaa aaaggggtgt caatagtttt gtaaaattta tttacaacac cccttttttg
     4681 aggtatacta attttaggag gtgtggtcaa tatgataaaa cgtccaccaa taaattattt
     4741 agaacgaaaa aagatactcg gaacaaaaat aaaagctata agaaagagta aaaaattaac
     4801 acaaccagca tttggtctta tgattaacaa cggtcaatta attgacaaaa agactatcta
     4861 cgaatgggag aagggaacct atttaccaat accagagcga ttatcccgaa ttgctgattt
     4921 gggaaatatg agtatagagg agttagtttg tggcaatgta gaagaatata ttttgggaat
     4981 tattctttat agagatagca ttgtactaga tggtataaca tttccagata aaaacctgtt
     5041 ccagcatctt cgtcaacagt tcccaccagt acactctaat ttagatacat ggctggatag
     5101 atattccaaa ttagaaccag agatgcaaga atttattgct aacaagactt gtaataaagt
     5161 taaaaatgaa aaaattagtc ttttcaatat cttaaaaata gaagaattat tcatcaatgc
     5221 tattgtagaa gaatttgaca ataacattct tttcctcact agcagtatag aagaactact
     5281 agaaagaatg gtagatgaat ggctacctat tcaattgaaa gacatgtctt atcccgaaga
     5341 agctgtgaga gaaattactg ataatataaa caagctagaa caaacgattt catcaattgg
     5401 gaaaaaatac actaagaaaa aaatgaaggg aggtgatacc atctagtggt aagtactcct
     5461 tgtaaactaa gaggagatga tttcatggca aaaatatcaa agtacaaaaa gaaaaacggt
     5521 caagtggcgt ggatgtataa aggacacatt gccaccgatc cacgaactgg tgaaaaaata
     5581 aatactacga gaagaggttt tagtagcaaa caagaagctc aaaaagatta tgacgagtac
     5641 agacatcaaa tattatacgg tgttaaaaag aaagcacctg atatgacatt tgaagacctg
     5701 tataatgaat ggataactca tcagcgtacc agtgttaaag cttcaacaat cgcaatctca
     5761 gtaagatacg caaataatca aatacttcca gcatttggta agcttaaact atcgaatatc
     5821 tctgtcccat attgtcaaaa agtggtagat gaatggcaca gtaaatatga aagttacgat
     5881 tatatgagaa aacagactgc acaaatttta cgctacgggg ttgcaatgca atatattgac
     5941 aataatccta tggaaaaaac acttcttcca cgaaaaaaag agtatgagaa aaatcgtaaa
     6001 ttttactcaa aagaggagct taataattta ctggatgctt ttaaagattt tggtaacatg
     6061 aaacaatacg ccttcttcag attattggca tacacaggta tgagaaagag tgaagtactc
     6121 gctttacagt ggaaagacat agacacgttt aataaagaac tacatgtcaa taaaactctt
     6181 gctgtagatg aatttggtaa agttataatt caatctccga aaacaagagc ttctagacga
     6241 gttatctctt tagatactga gactctttct atcctcaaca actggaaatt acagcaaaaa
     6301 gaagagtatt taaaacttgg atacaatact agctctaaag agcaacatgt ttttacaaca
     6361 gttaaaaaca ctctatacat tccaaacact gttaatgatt ggttaagata tattttgaaa
     6421 aaatataact tgcctcgtat tacacctcat gggtttagac atacacatgc tagtttatta
     6481 ttagaagcag gagaatctgt caaggtagtt caacaacgat tagggcatga aaatagtaaa
     6541 gtgacattag acatctatgc acatattaca aataatgcac ctaagaaaac aggtcaagac
     6601 tttgctgata tgatggctca tcagtaaaag agctggtcaa aatctggtca tttctagtat
     6661 acaggcaaaa caaaaaagct agaaccctta tatatcaagg gttctagctc ctataacagg
     6721 tttacccaac actgccttcc aatgactctt ttgggaatca gaggaaagaa tcaggcttta
     6781 tagagatatt tcatctaaca aattacttta gactgacagt atatatcagc aggtactgtc
     6841 atcgggaacg tagccaatat cgtatccaaa acagcaggta gagaagctat ttgaggattc
     6901 aagttattct atttcaacca tgaagttaag ttcattaaaa ataaagatag ttggtatttc
     6961 aataattttt gtatagagtt aatcacttta ttgatgctaa ttcatcttga ttggtattat
     7021 aatcgtattc aagttgcgtg gcgtgctttt gctagaaaat atataactgt tctttataaa
     7081 g
//
LOCUS       DADVXK010000119         6625 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.121, whole genome shotgun sequence.
ACCESSION   DADVXK010000119 DADVXK010000000
VERSION     DADVXK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.121"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1273..1938)
                     /locus_tag="KB909_002509"
     CDS             complement(1273..1938)
                     /locus_tag="KB909_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838474.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2118..4100
                     /locus_tag="KB909_002510"
     CDS             2118..4100
                     /locus_tag="KB909_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBB6838475.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="KB909_002511"
     CDS             4104..4742
                     /locus_tag="KB909_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838476.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="KB909_002512"
     CDS             4770..5198
                     /locus_tag="KB909_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838477.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5655..6566
                     /locus_tag="KB909_002513"
     CDS             5655..6566
                     /locus_tag="KB909_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6838478.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         2279 a         1004 c         1220 g         2122 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag cagcggaaga agaaaaacaa aatcgataac
     5401 atttgttcta agaattagtt acgttaaata cggaacgcaa gatagacttg aaaaacggta
     5461 acaaaagaag tagtatatta aggtgtgatg tgctacttga catttattct gctgagcgaa
     5521 ctttctggat tgtgtagcct tatatctatt caggacgtat cgagcagatt agtaaaggtg
     5581 ttcttgatga ttttcatctt gaacaccttt gtttttagca attcgcaaaa aacgaaaagt
     5641 aggagaattg ataaatgaaa aaaagatttt tagcacttgc catcgtacta ggcactggct
     5701 tattgtcagg ctgtacgaat gccggtgaaa aaacagccgt tagttataaa ggcggtacaa
     5761 tcagcgaaca agaagtaatg gatagcttga aaaaaatgca aggagcagat tccgctgtgc
     5821 aacagttgat cgtttatcaa gtatttgaag ataaatatgg agatgacgta tcaaccaaag
     5881 aaatcgattc tcaatatgat caaacaaaga aacaattggg tgattcattt gattcacaat
     5941 tgaaatctgc aggttacaca gaacaaacat tcaaagacag tatcaaacaa agtctagcct
     6001 ttcaagaagg tctaaagaaa catatcaaat tgaccgatga agatttaaaa acggcttggg
     6061 aatctttcca tccagaagtg gaagctcaaa ttatccaagt agcaagtgaa gatgatgcaa
     6121 aagatgtgaa gaaagctgct gataagggag acgatttctc taaattagcc aaagacaagt
     6181 caactgatac tacgacaaaa gaagatggcg gaaaagtgaa atttgattcc actactacaa
     6241 cggttccggc agaagtcaaa gaagcagcct ttaagttgaa agatggtcaa gtttctgatg
     6301 tgatcacttc taccaatgct tcaacttata ctacggaata ttatgtggtt aaaatggtga
     6361 aaaaccaaaa caaaggcaac gacatggata aatacaaaaa agaattgaaa gaaattgcaa
     6421 cagacacaaa attaagtgac agtaccttcc agaataaagt aattggcgaa gtattgaaag
     6481 acgctaatgt aaaaatcaaa gacaaagact ttgaaaatgt tttgagtaca ttcacttcag
     6541 attctagtac agcaagtagt aaataagcgg tataaataaa aaatatgaac tatttaaatc
     6601 aataaaactg ttcatctaaa tcttt
//
LOCUS       DADVXK010000120         6504 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.122, whole genome shotgun sequence.
ACCESSION   DADVXK010000120 DADVXK010000000
VERSION     DADVXK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.122"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            101..1519
                     /locus_tag="KB909_002514"
     CDS             101..1519
                     /locus_tag="KB909_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBB6838479.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            1590..3059
                     /locus_tag="KB909_002515"
     CDS             1590..3059
                     /locus_tag="KB909_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6838480.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            3069..3536
                     /locus_tag="KB909_002516"
     CDS             3069..3536
                     /locus_tag="KB909_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6838481.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            3572..4444
                     /locus_tag="KB909_002517"
     CDS             3572..4444
                     /locus_tag="KB909_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6838482.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            4525..>6504
                     /locus_tag="KB909_002518"
     CDS             4525..>6504
                     /locus_tag="KB909_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6838483.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIF"
BASE COUNT         2211 a          894 c         1310 g         2089 t
ORIGIN      
        1 ttcgtcgatt taaaaatatt tttatgaaac gggttgacat atgaaacggg ttgacatata
       61 ttagttgtga agataaaaac cttttcactg gaggaagaaa atggagaaat tattaattaa
      121 aagcaataat catcaacttt actaccaacc taaggatgtt tgggtcggag atgttatgcc
      181 ttacgggaaa gaaggaaaat tctttattta tcatcaacgt gatactagaa atccagttcc
      241 ttttggagaa ccgtttggct gggctttagc aactacgaaa gattttgttc attttgaaga
      301 ctttggggaa tctcttttaa gaggggatga caatgagaga gaccagttta tctacgctgg
      361 ttctgtattt gaggcaaatg gaaaggttca cgcattttat acagggtata atcgtgaatt
      421 cttagcgcag ggaaagacat ctcaagtgtt gcttcatgct gagagtgatg attttgttca
      481 ttgggaaaaa tcagaaacag cattggagtt agaaccacaa gaagggtatg atattcgaaa
      541 ctggagagat ccatttgtcg tttgggatga tgaaaaagaa gaatatttgc taattttagg
      601 ggcgcgaaag ggtcaggata aacatctaca aaccggacgt ttagtggaat ttacatcaaa
      661 agatttaact aattgggaat tcaaaggtga tttttgggct ccgggattgt ataccatgtt
      721 tgaaatgcca gaacttttca agattggtga ctggtggtat cttgtctatt cagaatactc
      781 agatggaaat aaaatactct atcgaatgag tcaaagtttg gaaggtcctt ggattaagcc
      841 taaagatgaa gcttttgatg gacgggctta ttatgcaggt agaacagctt atgatggaaa
      901 acgtcgagtc ctatttggat gggtaccaac aaaagatcaa gaaaatgata aaaacaatta
      961 tttatgggga ggtactttgg ttcctcatga agtctatcaa aaagaggatt tttcacttgg
     1021 ggtaaaaccc atagacgaag tgtggaatgc attcataaat ttacatgata ttgccgatgt
     1081 agagatagaa acagcagaca caagagaaga agtaacgctt gtcaaaaata gtggaacttt
     1141 gtttaattta gaaacaacaa tttcatttga tgagaatctt agtgactttt cactgagatt
     1201 atataaaaac cttgagacag atgaatctta cgaatatcgc ttcaatttag atgaggggcg
     1261 tcttacattt gataaaaacc cttgttaccc ttggtttcaa tatatggata aaggacttat
     1321 tagacctata tctttaaagc ctaaccaatc ttataaacta aaagtgattg ttgatgacaa
     1381 tataatgaca ctttatattg atggaatcgc tcttaacgct cgtgtacatg gttgttttgg
     1441 tcaagcaatt actattacag caacaaatgg atcaatgact gcaataaata ccaagttttc
     1501 aaatgaaata aagaaataat aaacgtcaat catgtggcag gtctgaaaat caaacatgac
     1561 ctgtcacatt taaaagggag gataaatgaa tggactacaa aaaaattgcc gaagatgtat
     1621 tggaaaacgt tggaggaaaa gagaatatct caagcgctac acactgcatt actcgtttac
     1681 gtttaattct taaagacaaa agcaaagcga atatggaaat gcttgaggaa atagaaggtg
     1741 caaaaggtgt tcttttcaat agtggacagt tacaagtaat tttcggaaca ggtataattg
     1801 aaaaggttta caaagagttc gttgaattga caggagctaa ggaagtatcc gtttctgaaa
     1861 tgaaagacga aggagtcaat aattcaggaa atagacttca acgagctttt aaagttttct
     1921 cggatatctt tattccgatc attccagctt ttattggggc agcaatggtt ttaggaattc
     1981 gttcgttgat taccactcct ggaatgtttg gaatggatgg ctcattcgct gatcacaatg
     2041 tattcctaaa tgatttatcc aaatttctgg gtattattgc aaccacattt gattatttac
     2101 cagttttagt tatgtattct gcaacaaaac gttttggcgg aaaccctatt ttaggattac
     2161 ttgtaggatt tgttatgatt catccaggac tagccaatcg gaatgatttc gtcatgggaa
     2221 ctataaagcc tgattattgg catttatttg gattaagcat tccagcagtt gcgtttcaag
     2281 ggggtgtttt tccagcaatt ttgacttctt ggtttttagc aaaagttgag aaaattacaa
     2341 ataaatattc tcctcaagta cttgcttaca ttttagtccc aactgtgaca attgttcttg
     2401 ccaactttgc actattttta gtgtttggtc cattggggaa ttttatcggt aatgttttag
     2461 gtggaatcat tgatttccta tatatgaaga tgggtgcctt tggtgctttt gtttttgcag
     2521 gcgcgttaca accattagtt gtaacaggaa cacaacatgc tattcaaggt attgaggcaa
     2581 acttagtcgc aacaactgga ttcaattata tccaacctat ttggtcagtt tcaattattg
     2641 cccaaggtgg cggttgtatt ggtatgtatt tactctttaa gaaaaaatct aaagatagag
     2701 atattgcgat ttcaagcttt attccaacac tggtaggtat tactgaaccg gctatctttg
     2761 ctgttaattt gaaatattca atcgttcctt ttgtttgctc gtttattggt gctggttttg
     2821 gtggagcatt tatgaaaatt tttgatgtaa aagccattgg acaaggattg actgtattgc
     2881 caggtctgac tattgctaat ccagttcttc cttatatatt tggtaatctc atagcattca
     2941 ttttaccaat catttttatt ctcgcttatg ataaatataa agtgtttatc cctgaagcta
     3001 aacaccgtaa atttgcagaa aaaactgact caaaaaaatt gccagttcaa gtaaagtgag
     3061 atgagagcat gttaaatttt tttagaaaaa atgaaataag cgttgtagca cctgcaaccg
     3121 gtgtttttga aaaactggag aaattaagtg atccagtctt ttcaaaagga atgatgggac
     3181 aaggatttgc aattgatgca aaaaacgaaa cgattgtatc tccaatcgat ggttttgttt
     3241 caagtatttt tcctacaaaa catgccttag gaataaaaac aaaatcagga attgagatac
     3301 ttgttcatgt aggaatagat acagttgagc taaatggtga gggatttgat attaaagttc
     3361 aagaaggaca aaaagttaag gctggggata ttcttatgac cattaatttt gtagtttttg
     3421 aaaagaatca caagactaaa gatgtcattg ttgtttttcc agactaccaa gacgaaattt
     3481 tcattccgaa acttgaagaa gtaaaacaag gacaagaatt gtttgttctt ggctaatgat
     3541 aagtaattaa taatagaatc gaggaaaatg tatggttttt ggggctattg aagctggtgg
     3601 aacaaaattt gtttgtgcca ttggagataa agatttgaac atatttgaaa aagtcagctt
     3661 tcccacgact acacccaaag aaacaatgaa tttagtttta gattttttta atcatcataa
     3721 agatgattta gaaggtatcg gagtgggatc gttcggtcct attgatattc attgtgaatc
     3781 taaaacgtat ggcttcatta aatcaacgcc aaaacttgct tggcaggatt ttgattttat
     3841 tggaagttta aaaaagcaac ttaatattcc aactgcttgg acgactgatg taaatgcctc
     3901 ttgctatggt gaatatgttt ctggaaatgg cagaggcctt tcaagtgttg tttactatac
     3961 cgtaggaacg ggcataggag gtggcgctat ccaaaacgga aacttcattg aaggttttag
     4021 tcatccagaa atgggacata tgcttgtaaa acgacacaat aaagacaact tttctgggac
     4081 atgtccattc cacggagact gtttagaggg cttagctgct ggtccggcaa tcgaaagaag
     4141 atcagggaaa aagggacaag aagtgactga aaatgacgtt acttgggaaa tagaagctta
     4201 ttacattgct cagtgtgcat ataatacaac attgatgtta tcacctgatg tcattatatt
     4261 tggtggcgga gtaatgaaac aaaaacactt aaaaaagaaa gtacaagata agtttattga
     4321 gttgatcaac ggatatgtcg ctattcccga tgttgacaat tatattatga caccaaaatt
     4381 gttagataat tctggtattg taggttgttt agctttagca agagacgtta aagaaaaatc
     4441 ttaatttgga aaaaagatcg tctcgactat ttgtttggtt gatgcgatct ttttttcaat
     4501 tagtaattga agggacgcct aaaagtgaaa aaaaaaatga aagatgaagt attagagtat
     4561 atcaaaaata atttaaagta ttacgatttt tctgctcaag atattgcaat gaaattttgt
     4621 attaaaagaa atgtcgcttc ccactatttg aatcagttat tttcagatgg aaaattacta
     4681 aagaatgatt ctgttagacc agtaatgttc aagtataatc aacaaaagcc aaaagactgc
     4741 ttttctaagt ttattggagc agacatatct ttgaaatcca ctatagataa atgcaaagct
     4801 actgtaatgt atccccctaa tggcctccca ttaataataa aaggaaacag tggcgttgga
     4861 aaaagttttt tagcaagttt gatctatcag tatgctcttg atagaaaagt aattcataat
     4921 gacgcaaaat ttgttgttgt gaattgtgca gattatgcaa ataatccaga gctattgtca
     4981 gcagttttat ttggatataa aaaaggagcc tttactgggg ctgaaaaaga tactgcaggg
     5041 atgctatctt ctgctaatgg aggatacctt tttttagatg aggttcacaa tctaagtgca
     5101 gaaaaccaag agaaattgtt tcttcttatg gattctcaaa agtatcgtaa acttggtgaa
     5161 agtgtgcaat gggagtatgc aaatgttcgc cttatcttag ccacaacaga agataaaaat
     5221 acctctttgt tagcaacttt tagaagacgc atcccagctg aaatcactct gccagattac
     5281 aataatagaa gtacatctga aaaaattcaa ttattatttg aatttcttaa agatgaagca
     5341 attacgattg attcaaaaat attttgttcg attgaacttt ttactgatct tttatcgaaa
     5401 acatttgaag gaaatgttgg agaattgagg aatgaaatca agcttctttg tgcagaaggt
     5461 tatttaggaa ataagagaaa gtcttcaatt tatttagggg acaaactaga cagcggtttt
     5521 tggatagatc cagaaattag tatagattta aaaaaaatgt ttcttaaatc actttctgaa
     5581 attgatttga ttgaactttt tcaaaatcac atttcaattg aagaaagcat gagtcaatta
     5641 agagatagaa tacttaaaga gtgtgcaggt tcttctgagt ataattattt agaaagtgac
     5701 gaatttatag cattaagaaa ctatgttgtt aataaaatat caccaattat tgattcgaca
     5761 ggtctatgtt tattagatga attcttggcg gatatcagtc tatttataat gtttattgat
     5821 gtaattgaag aaacatcaag aaattttttg ctgtctaagt tcagaaaatt tcgtatgaaa
     5881 aatgataaac aaaaattatt ggcaaatgag atttggagta gtttagaagt cgaagaaagt
     5941 aaacaagaac ttttgttgaa atggatactt tttcttgtaa agaagttcta tgtgaaaata
     6001 ccagaaaccc attgtctgat agttatgcac ggtaaaataa cagcttctgc gatcgcaagg
     6061 gaaacaaata agttgctgaa tacatatgtt tatgaggctt tcgatatgcc aattgaaggt
     6121 gagactagtg acttaattaa cctaatcaac aatttttgta aaagtataga tacgacgaat
     6181 ggactcattc tgctagttga tatgggatca ttggaacaaa tgtatgaaaa aattgaatcc
     6241 aatgtaatag gtgatttggt aattttaaac aatgtttcta cagctttagc gattgaatgt
     6301 gggattcaag tttgccaaaa aaagccaatt agtcattttt accagatgga ttttgattcg
     6361 tttcaagtta aagttcagta ttataaagga ttatcacaaa agaaaaatgt aatagtatct
     6421 tgtctctctg gtgaggggat ttctgaaaaa gttaaggata ttttaaaacg gtatctcgat
     6481 aatcaagtgg agattttgat tttt
//
LOCUS       DADVXK010000121         6439 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.123, whole genome shotgun sequence.
ACCESSION   DADVXK010000121 DADVXK010000000
VERSION     DADVXK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.123"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(99..1229)
                     /locus_tag="KB909_002519"
     CDS             complement(99..1229)
                     /locus_tag="KB909_002519"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBB6838484.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="KB909_002520"
     CDS             complement(1878..3080)
                     /locus_tag="KB909_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838485.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="KB909_002521"
     CDS             complement(3140..3343)
                     /locus_tag="KB909_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBB6838486.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="KB909_002522"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="KB909_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="KB909_002523"
     CDS             4880..5692
                     /locus_tag="KB909_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838487.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1932 a         1315 c         1009 g         2183 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaat
//
LOCUS       DADVXK010000122         6415 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.124, whole genome shotgun sequence.
ACCESSION   DADVXK010000122 DADVXK010000000
VERSION     DADVXK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.124"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..316)
                     /locus_tag="KB909_002524"
     CDS             complement(<1..316)
                     /locus_tag="KB909_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HBB6838488.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILT"
     gene            complement(370..2187)
                     /locus_tag="KB909_002525"
     CDS             complement(370..2187)
                     /locus_tag="KB909_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6838489.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            complement(2201..2965)
                     /locus_tag="KB909_002526"
     CDS             complement(2201..2965)
                     /locus_tag="KB909_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBB6838490.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            complement(2993..3691)
                     /locus_tag="KB909_002527"
     CDS             complement(2993..3691)
                     /locus_tag="KB909_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBB6838491.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(3703..4482)
                     /locus_tag="KB909_002528"
     CDS             complement(3703..4482)
                     /locus_tag="KB909_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBB6838492.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(4498..5442)
                     /locus_tag="KB909_002529"
     CDS             complement(4498..5442)
                     /locus_tag="KB909_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6838493.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(5488..6267)
                     /locus_tag="KB909_002530"
     CDS             complement(5488..6267)
                     /locus_tag="KB909_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838494.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT         1694 a         1324 c         1142 g         2255 t
ORIGIN      
        1 aagttaaaat tttgttctca caaatgtcga tgactttttc tgaagaaact aatacaactg
       61 agtctgtttc attttcaata tattttttat ttcttgataa tgttgataat tcagtatcaa
      121 tagtaggaac aattaattta atttcaaaaa actttattac ttttattaat tcctcaatat
      181 aattactttc tgaaacttta ggtaatacta ttttttcgtc acacatatat agtgcgggtg
      241 ctagttcaga gcaatctgct ccaatgattt ttccttccat ttcattattg tttaatgctg
      301 ttttaaatgc attcactagt tcacaacgac gtccacaact taatattaaa atattcaatt
      361 tttaatctcc tatctattcg aagcatttgc aaaagtgaca atgtctttag ccaattgttc
      421 atcgtcttgc ggcaggctct tgacaaaatc catcactttt tgtattgagt aacctttgat
      481 gtttcctaca aagattttct cataaactgc ttcatcattt ctttccttat ccaacaatag
      541 ttcttcatat agtttttccc ctggacggat acctgtttca atgatttcga tttcgtcttc
      601 gctatacccg ctcaatcgga tcatgttttt cgctaggtct acaatcttca ctggttcact
      661 catatctaga ataaaaattt cgccaccttt tgctaatgcg ccagattgaa taactaaacg
      721 actagcttca ggaatcgtca taaagtatcg agtcatacga aagtctgtta cagtgattgg
      781 accaccttga gcaatttgtt ctctgaatac tggaatcaca ctaccgcgag aaccaaggac
      841 attcccaaat ctgacagctg agaatttcgt acagccttct tcattcaatc cagtcacaat
      901 catttcagcg attcgttttg ttgaacccat gacatttgga ggattgttag ctttatctgt
      961 cgataccatg acgaagtttt tcacttttgc tgctttagct gcttctgcta cattttttgt
     1021 accgaaaata ttgtttttga ctgcttcttt tggattatat tccatcagtg gtacatgttt
     1081 atgagcagct gcatggtaga cgatatctgg atgatattgt tccatgatct cattgatttt
     1141 ctcgcgatct tggatatctg cgatgatcgg tacgatttct gtaggacaat tttgatgatg
     1201 cgtgcgtaac tcacggtcaa tcaagtagat cgagttctcc ccatgtccta aaagcaatag
     1261 ctttgcagga ttgaattgaa tgatttgccg acagatttct gaaccgatcg atcctcctgc
     1321 gccggtgaca agaatgactt tgtctgtgat ctgatctttg atggattcaa tatccagctt
     1381 tacctcatct cttcccagta aatccactac gtcaattgtt tttaattttg atacgctaat
     1441 tttccctgaa gcaagttctt ctatagaagg catcgtgttg actttcacac gagcggattc
     1501 gactaactcg aagattcgtc gtaatttttt tcttgataag gaagggatag cgatcgttac
     1561 catttgaatg tcatattttt caatcaattc cggaatatct tttaatgcac ctaatacttt
     1621 ttttcctgaa agatacgtat ttcttttatt tggatcatca tctacaaacc cgacaacgtg
     1681 gatatcttga gccgttttgg atccaagaaa gctgttgtat aaaatacgcc cgccttcgcc
     1741 agcaccaaca atcaatgtat ttttagcaga atctgctgat acgtatctca tattttttgt
     1801 ttcgatgtag atacgccaga tcaatcggct accgatgatc aataagagcg aaagcagata
     1861 agcaaagata actaaccgta aactgtatcg ccgattaatg aacagcagta tgaggatact
     1921 tgaggcagca cttgcagata gtgaactaaa aattgcaatg atctctctta aatttgtata
     1981 gcgattgatc cgagtgaaaa ctttgaataa actaccataa aataaataaa aaccaatcga
     2041 caaaccgata gagattaaaa taagatccat tggtatagat acaaacggct tcatgaattt
     2101 agctgctgca atatttgcag caattaataa caagctgtcc acaaaaacca atgtggcaat
     2161 ttttcttctt cttgttaata taaacacttt ttaattcccc ctaaaataaa ccaaacttct
     2221 tcttttttac ctcttcatag tctggataac tgatttcatc cccgttgatc agatcctttg
     2281 caacttgctt catctgtact actttttcct taccaaagtc cttggcaatc tgctcatagc
     2341 actcttttaa gtaaaaggtg cgcttagaga ctccgtgtgc atcagaagca gtcatctgca
     2401 cgagattatg tttgaccatt gttttagctg ttttctgaat atctttgcca aataccccaa
     2461 cataacttgg cgcagtaagt tgggccaaac accccatatc taggaacgga agcaaatgat
     2521 tcgggtcttc gcgaaaatgc gcgttgcgtt ctggatggac gatcactggt gtctttccta
     2581 gttctaacaa ctcaaaaaaa agccgttctg catataacgg cacttccagt gtcggaaatt
     2641 cgatcagaag atatgtatca tctaaatctg taaataaaat ttcatctcgg tggatgtctt
     2701 cgatgagcgt tccggtaata cgtacttctt gtccttccaa taacgtcaaa ggcaactgtc
     2761 ttttctctaa ttcggcttgt aacgaagcga ctagagaaat gacttgtgat ttttcattgc
     2821 tgtattttcc attattgtgg tgtggtgtgc ataaaatatg cgtgatgcct tgctgaatcg
     2881 ctttttcagc cattgcaata cttgcttcta agttttctgc cccgtcatcg attcctggta
     2941 ggatatggca atgtagatcg atcatttctc ttgtctcctc tcttcttatt ccttaatttc
     3001 cgtagtaata accagcatct ttgctatgtt ctgctccgtt gtatacaaca cctaaaactc
     3061 gtgcttgtac catctctagc agttcttttg ctttattcaa tgattcttta cgtgatgtat
     3121 tttcacgtac gaccaataaa gtgccatccg tttttgaaga catgatctgt gcatctgtta
     3181 cggctactac tggtggcata tcgaatatca ccacgtcaaa taactgtctt gcttcgtcta
     3241 ggatctgatc cattcttggc gaacttaaca attctgatgg gttgggtggc ttaggtccac
     3301 taggcaaaat cgacaagttc tcgactggcg ttcgttggat tacatctgct acacttcctg
     3361 atgaactaag tgctgtactt aatcccctgg cattgttcag ctggaatgtc ttatagacga
     3421 cgggtttacg taaatctgca tcgactagta gaactcgttg accggattta gcaaaaacga
     3481 ctgcaatgtt tgctgcagtg gtggattttc cttctccagg acctgatgaa gtcacgacaa
     3541 tcgttttgat ttgctgacca gctgcggagg caaactggat attcgtccgg atcgtacgat
     3601 attgttcggc gattggtgaa gatgggtttg ttaatgtgat caaactgact gcatgagttt
     3661 gtgctgcttt ttgtttctgt gttcgtgcca tttttcttcc tcctagactc ttgagcggct
     3721 tctgcgtgat ggggctgttt tatcgtttgt agcttttggt cgtgcaggag ctgttccttt
     3781 tttacggata ccagcgttca attctttcgc tgacatttct ggaactgttc ctaagattgg
     3841 gaatcctaat gcatccgtca catatttttc atctttcact gtccgatcaa gtaattcgaa
     3901 taagaatgcc agacctacgc ctaccatcat tcctaatact aagccaatca ctagattcaa
     3961 tttattattt ggcgaaacag gtgtcgtatt ggcaactgca cctgaaataa tcgagatttt
     4021 atcgacattc atcacgtctt ttgcgttctc ttggaaaact tgtgaagttg tgttagcgat
     4081 ctgttgagca gtcactgcat tcgtgcttat tgcctggatc gagaacattt gtgaattttg
     4141 tgactgattg acggagatcg catctttgat ttgtccagca gtcattttca cattgtcttc
     4201 tgtttctaaa cgatctttga cttcatttag tactaaatca ctgacgatca tatctttata
     4261 cgtattgatc atttgcaggt tcgtattgac atcattgaca tttgctgtgt ctgattgtgg
     4321 cagtgtcacg atcaattgtg cttgtgaact gtattttggt gtcaagatga aaaatgttac
     4381 gattcctgag atggccaagc cagcaaacat tgagatgatg attgttacca agtgtttgcg
     4441 taatgtttca aaaatttctt tcaagctgat tgtctcttcc attttttctc cactttccta
     4501 tttattctct agattcattt gatcttttaa ttcttttttc acacgatcaa gttcttgatc
     4561 gctgactttt tgataggaga tattatcttg catgaagcct tctccttgca gctgatcttg
     4621 cttgatcgta ccaaatgcct cccgataatc taaagcgatt tttttcattt catcaaagct
     4681 catgtctgtt ttcatattcg actctagagc attcaaaacg gattgatagt tgctgacacc
     4741 gtttaaactc aatacttttt ttgctacacc ttctacgatc tttctttgac gctcttgtct
     4801 accatagtca ccatttggat cttcataacg catacgagaa taagataatg cctgatcccc
     4861 gttcaatgta attttaccga ttggaaagtc atagccatct tgtgagaaag tgaggtcatt
     4921 attgacttcg ataccaccaa ctgcatcaac gagttccttt agccctttca tattgataga
     4981 gacatagtga tcgattggga tgtctacata tttttgtagg gtatccatcg ccatggcagc
     5041 tccgccgaat gcgtaagcgt ggttgatctt gtcttttgtg tcacgaccta cgatgtcgac
     5101 atacgtatct cgaggaatgc tgacgatcgt tgtctgtttg tcttcaggac tgactgtggc
     5161 aaccatcatc gtatctgatc ttccttgatc gacccgacct aaatctccag tatcaatgcc
     5221 catcaataga acagagaaag attcttgttt gtccagatca actggtttcg ttcgttctcc
     5281 ttgggttcgt tccactgatt cgtaagtttt ctcaatagaa tgtgagagat ccagatataa
     5341 ttttgctcct actcctacaa ttgctaatac taatacgata agaactgcta aaataatcag
     5401 aaatattttt ttccctcttg attttcttct tcgtcttgcc atagtttcct ccgtttgcta
     5461 accttgcttg aatcaacgtt ttaactgtca ataacttata ttgctatagc ccatttgctg
     5521 agcaacagtt tgtgcttttg ttgcgtatgc tgcgcttatt ttttcattcc ggatctgctc
     5581 tatttgactg agcgccgtca aatattgatc gtaagtagcg gtggcagtca cttgaccatc
     5641 cttcaacatc gtatcgaata actgatctag ttgcgtgact tgcgcgatct gagtatcagc
     5701 gaatcctaga tattgcataa caaccgtttt ccaaggacta tctttaaaaa agctcatatt
     5761 ttcacgtaca cgagcgacat ctgcacttgt caccttttct ttgatgacga catcgtctac
     5821 agcttgctgc cagtttgata catttttagt aaataaatcg ttgacagctg tctggatctt
     5881 cagttttgat tctgcactat ctaactgtgt cacgattgct ttcttctcat cttggattgc
     5941 aacagcttct ttaggcaatt ctgattcttt gatgtcgtaa tcatctgctg aaagtttgac
     6001 agaggatagc ttatttgaca aacttgtgat tgtttcttct gttatttcag ggtttagaaa
     6061 atttttttct tttgtactat acagcttgtc tacttctttt gataaagaag tcaaggtgtc
     6121 tttttgattg gtgatggcag attctgcata attgatccgt tgctgatgtt gccgctgatt
     6181 attgatatgg taaccaaaca aacagatcgc aatagcacct gcacctaccg ccacagcagt
     6241 caatgacttg acgaatggct tttccataga ttcactccta agtattgatg atagataaat
     6301 taagatataa ttcacataca taaaaatgac agctttttat tttaaaaaac ataattaaat
     6361 taatatattc acagaaatat ttgtaaacaa gttttcccta tataatcata ccaca
//
LOCUS       DADVXK010000123         6396 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.125, whole genome shotgun sequence.
ACCESSION   DADVXK010000123 DADVXK010000000
VERSION     DADVXK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.125"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..2587
                     /locus_tag="KB909_002531"
     CDS             <1..2587
                     /locus_tag="KB909_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBB6838495.1"
                     /translation="LNKKTVSHIFSTADSQAIINYLEKQKLSEGTVNITYNPIKQEVI
                     TQKKHSVRDNDIEKIRFVFIDIDPKRKEGSATDSEKKKAENVMEQVERYLKEKRIESF
                     VKVDSGNGYHIFLPINEQPNNHETILTIQNFLQLLHRRFGVEDEVDIDTSVYNPSRLC
                     KLVGTPAVKGKSTKERPHRLSSFLSIPDNIDRSNCFKILEQIVEENSMMSTSRVKSHP
                     SFREVLPFIQADYKQWLAHYPELTYTIKEGDHKGVTLLIFDECPLRKHTNNSNGSCLS
                     VTADNKIRFHCLHASDKNKDIQDFVKKYPLPKPVNPSVESLESNQEYYFDQFKLNQEG
                     VFLVKEGQEEKVACPMFIKQIRKNIEQKVITLVLAYYVDHCWDEIEIEGGCLQTNNFK
                     QLAKHGLIIKARREAEVVDFLQIQRENAPIFFEHESLGWKKENEAMIFQLQDSFGREI
                     PSVLTKNSCYQLTTNGTEAEFDALVHKYVLGTNLELAWSIGIASIVLGYLNVTKANTF
                     LSLLINLQGKSTTGKTTTLHFIASLFGNPTTVLRNMNATNKAIIKLASNNQGGVPLIL
                     DELGAATQNNFSSLIYQLASGEERLRLDSNCQLMPQETFSVLTLTSSEERLENYFNEK
                     LTGLKVRYIEFSDIKFTKDANHAEKVKSLSSNTFGWGIKLFLLKLFEQGITKIEATFV
                     EAQKKLWAVLPEHSLKQRIGNNLALIYSGALLIQDILGYPLRLEHIQTVLINSYEQLI
                     VDTSLGSEQTVFDRVKTLLVMNSHKFLTNSDNKHTPSTIWGKVSIQKNGDIKVNIFPI
                     PFEDLLRREFQVKDLTYLFRQLLDSGNMCAEKGRRTKRIHMNRQVLPTYEILLPSSLK
                     SYFRL"
     gene            2769..3008
                     /locus_tag="KB909_002532"
     CDS             2769..3008
                     /locus_tag="KB909_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838496.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3024..4397
                     /locus_tag="KB909_002533"
     CDS             3024..4397
                     /locus_tag="KB909_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6838497.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4401..6035
                     /locus_tag="KB909_002534"
     CDS             4401..6035
                     /locus_tag="KB909_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6838498.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6198..>6396
                     /locus_tag="KB909_002535"
     CDS             6198..>6396
                     /locus_tag="KB909_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838499.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2241 a         1046 c         1290 g         1819 t
ORIGIN      
        1 attaaacaag aaaaccgttt ctcatatttt ttctactgca gattctcaag caattattaa
       61 ctatttagaa aaacagaaat tgtctgaagg tacagtaaac ataacttata atcctattaa
      121 acaagaggtg attacacaaa aaaagcattc tgtgagagac aatgatattg aaaaaattcg
      181 gtttgtattt attgatattg accctaaaag gaaagaggga agtgcaacag atagcgaaaa
      241 gaaaaaggca gaaaatgtta tggaacaagt agaacgttat ttgaaagaaa agagaataga
      301 atcatttgta aaagttgata gtgggaatgg ctaccatatt tttcttccca taaatgaaca
      361 accaaataat cacgagacga ttcttactat tcagaatttt cttcaattac ttcaccgaag
      421 atttggagta gaagatgaag ttgatattga tacttctgtt tataatcctt caagattatg
      481 caaattagtt ggtacaccag cggtcaaagg aaagtccaca aaagagcgtc cgcatcgttt
      541 atctagtttc ctttctattc ccgataacat agatagaagt aattgtttta aaattcttga
      601 acagatagtt gaagaaaatt ccatgatgtc aacctctaga gtaaaaagcc atccatcttt
      661 tagagaagtg ttacctttta ttcaagcaga ctataaacaa tggttagctc actatcctga
      721 attaacttat accataaaag agggcgatca taaaggagtt accttactta tatttgacga
      781 atgtccatta agaaaacaca cgaataattc taatggttct tgtttgtctg ttacggctga
      841 taataagatt cgatttcatt gtctgcatgc ttcggataaa aataaagata ttcaagactt
      901 tgtaaaaaaa tatccgttgc caaaacctgt aaatccttct gtagaatcat tagaatccaa
      961 tcaagaatat tattttgacc agtttaaact gaatcaagaa ggagtatttt tggtgaaaga
     1021 aggtcaagaa gaaaaagttg cttgtccgat gtttattaag caaatacgca aaaatatcga
     1081 acaaaaagtc attacacttg ttcttgccta ttatgtcgat cattgttggg atgaaataga
     1141 aatagaaggt ggatgtttac aaactaataa ttttaaacaa ttagcaaaac atggcttaat
     1201 cattaaagct agaagagaag ctgaagtcgt tgacttttta cagattcaac gggagaatgc
     1261 tccaatcttt tttgaacatg aatctcttgg ctggaaaaaa gaaaatgaag caatgatttt
     1321 tcagttacaa gattcttttg gacgtgaaat tccttctgta ttaactaaaa actcatgcta
     1381 ccaattaaca actaatggta cagaagcgga atttgacgca ttggttcata agtatgtttt
     1441 aggaacgaac ttagaacttg cttggtcgat tggtattgct tctattgtgt taggctattt
     1501 aaacgttacg aaggctaata cttttttgag tttactaatt aacctacagg gcaagagcac
     1561 aacgggtaaa accactacgt tacactttat tgcctcttta tttggaaatc caactacggt
     1621 tcttagaaat atgaatgcta ccaataaagc cattataaag ctagcatcaa acaatcaggg
     1681 aggtgttcca ctaatactag atgagttagg agcagcaact caaaataact ttagctcgtt
     1741 gatctatcaa ttagcttcag gagaagaaag gctaagatta gattctaatt gtcagcttat
     1801 gccacaagag actttttctg ttttgaccct tacctcttct gaagagcgtt tggaaaatta
     1861 tttcaatgag aaattaactg gtttgaaagt tcgatatatc gaattttctg atatcaagtt
     1921 tacaaaggat gcgaatcacg cagagaaagt taaaagtctt tcttctaata cttttggttg
     1981 gggtataaag ttatttcttt tgaaactctt tgaacaaggg attacaaaaa ttgaagcaac
     2041 ttttgtcgaa gctcaaaaaa aactatgggc tgttttacct gaacattctt tgaagcaacg
     2101 cattggtaat aatctagctt tgatttatag tggagccctc ctaattcaag atatactggg
     2161 ctatccttta cgattagagc atatacagac ggtgcttatt aattcgtacg aacagttaat
     2221 tgtagatact agtttaggaa gtgagcaaac ggtatttgac cgagtgaaaa cattgttggt
     2281 gatgaatagc cataaatttt taacaaacag tgacaacaaa catacgccca gtacgatttg
     2341 gggaaaagta tcaattcaaa aaaatgggga tattaaggta aatatttttc ctatcccgtt
     2401 tgaggacttg ttaaggcgag aatttcaagt aaaggatcta acctatcttt ttaggcaatt
     2461 gcttgattcg ggtaatatgt gtgcagaaaa agggagaaga acgaaacgta ttcacatgaa
     2521 tcgtcaagtt cttccaacat acgagattct attaccttct tcactcaaat cgtattttcg
     2581 attgtaattt agaataaacc aaagtatgaa agtgaggcac catgttatgg aaatatttct
     2641 tattgattta gcaaaacaac tgattactta tctgtatgat agcgagcaaa cccaaacgga
     2701 agtaaatgaa gcttgatcta tgcttcattt acttcattca atcaaacatg aaagaaagga
     2761 aaattctaat gactaaaaat aaaatgacac taaaagcaga ggttcttctg tatattcaag
     2821 aacatttttc aaatcaagcc ttttttacaa aaccaattta cttggatttc gaaataagag
     2881 gggtatctgc tggatctatc gggggtactc ttcaagcgtt gaagaacgaa ggatatttag
     2941 aaaatcactt tgtgcaacgt tcgttcaata gaagagtcgt gaaaaaatgg tatttagttc
     3001 attcatagag aggggaatca agcatgcgtg tggcttgtta tgatcgaacg tctgtttatg
     3061 aagaagcgaa aattagtaat gacgctcaat atgatgcagt gaaagagtat gttttagaga
     3121 aatatgaaca aattccccaa cgattttcag acaaaggaga atcaggggaa aaagcggagc
     3181 gtccagcttt tcgacagctt agagcttggg tttgtgcgtc agaagaagag ggggtgatct
     3241 atgtttggcg ttatgatcga ttggcacgtc aagccaaaat agccttagaa tttattgagt
     3301 tgtgccaaca acatcaggtt caagtgtatt cgatttctga acctcttcct gcttctttct
     3361 cacacgcgtc aacgaataaa ctatttgtgc aattattgtt cacttttgca gaacaacaac
     3421 gaaacgtcat tattgagaat gttcgtgccg gactttccta taaaaagcaa caacggcaat
     3481 atttgtcttc tgcggtacca tatgggtatc gtttagtgaa tgggaaaatc caacaagaag
     3541 tacacgaagc aaggattgtt cgctatattt ttcaacttta tttgaccaaa aaatatggct
     3601 acaaaaagct ttgtcaacga ttgacgcaac aaaagctttt cttccgcgaa cgtccttttc
     3661 agccctatca tatttatagt atcctaaaaa atccattgta ctatggcgaa atcaaaggag
     3721 gatctttggg gaagtatcta ggaacctttg aaccgattct ctcgaaagca acctttttac
     3781 aagcccaaga gattcgccaa tcaaggtgta cagctaaaaa agatacgtat ctgtacttat
     3841 tacgtcaaaa aattcggtgt cccttctgtg gtcgtcatct gagttcgaag tatcaatgga
     3901 atacaaagaa gacgaagacg cttcattatt atcattgtac cgaccgaagc tgccaaggaa
     3961 tttttcttcg ggcagaaagg gttgagtcag aagtattgga aaagatacag gctttttttc
     4021 aatacgaagg cgtctatcaa gccttgattg cccaattaac gcaacaatta gccgaaaagc
     4081 gaaaagatga aaaacgcaaa gtaatccaac aaaagaaaca agaagcacaa tggattaagg
     4141 catttgaaga gggcaattgt tcactggaag aactcaagca acaactgcaa gctcttcaaa
     4201 agccgatgtc tacttcttcg tttctttcac tccaacagtg tgaagcaaaa gtgaaagaat
     4261 ggcttcaact aaaagacctc tctagtcgac aattattatg tgactatgtt tgtcggattg
     4321 aggtaacaaa ggataaaaca gtttgtggga tttacttccg acaactgaca caaaatattt
     4381 tagaaaggaa cgaatgatct atggaaatga tacaaaccaa acgagtcgca ttgtatattc
     4441 gcgtgagtac acaagaacaa gctttagaag gacatagtat tcaagcacaa gaacaaaatg
     4501 gacgacagtt tgccgaacgg atgggctatg aagtggtaga agtttatgcc gatgaaggaa
     4561 tcagtgggaa atccacaaaa aatcggttcg cctatcaacg aatgatgaac gatgctcgga
     4621 accatcgttt tgatctacta gtgatttgga aattgacccg tctcggacgc aatatgttag
     4681 atgtcttaca aacagtcgag gaattattgc gatatgacgt aggattacat tcgatctcgg
     4741 aacaatttga cgtgaccact tcgacaggta aattgatgtt acaactcctt gggagtttcg
     4801 gtgaatttga acgcaaccaa attgcggaga atgttcaaat gtcaatgcaa agcttagtga
     4861 aagataaaaa gcgttatgca ggaggccgac gtttaggcta tgtcagtggt attgacacga
     4921 atggtcaaaa acaattggtc attgaaccag aagaggcgaa aattgttcgt ctgatctatg
     4981 caaaatattt aggcggagca gggtatcgag cgattgccaa ttttttgaat cgtcaaggat
     5041 atcaaacagt caaaaagaat gctttttcta ccacggcagt caaagatatc ttacgcaata
     5101 aaatttatgc agggtattta gaatatgcgc gctacatcaa ttgggaaacc aaacgacgga
     5161 aggggaagaa tccgagaccg attttagtga aaggaaccca tgaaccgatt atttcggaag
     5221 aagattatca aaaagtacaa gaacgccttg ctttagaagg aaaacaaccc aaatggaacc
     5281 atacaggtga aaatgtattg acaggcttgt tacgttgtcc agaatgtggc gcaccgatgg
     5341 cagcgagtaa tgtcacaaat accctaaagg atggcacaaa gaaacggatt cgatattatt
     5401 cttgttcagt ctttcggaat aaaggagcaa gtgtgtgtca tgccaattcg attcgtgccg
     5461 aacaagcgga aacatttgtc gccgaccgat taaaggagat cgttcagcta ccagaagttc
     5521 ttccccgatt ggtggcagcg ttaaatgaag aaatagtgcg acaaagccaa ccattggaac
     5581 aagaactcgt ggtgttactg gaacgaaagg aagaattgaa gactaaaatt gaaaaatggg
     5641 aagctgcttt ggaagatagt cctgaattgt ttccgatgtt aaaagaccgc ttagacgaat
     5701 tgactgaaaa acgacgacag ttgcacattc gagaaaatga aatcttaggg atctttcaac
     5761 aaggagagcc gattcaagtc aaagatgtcc aacggatatt gactagtttg gatcgttttc
     5821 ttgcccagag tgagaagaag caaatcaaag ccttgtatcg tacctttata gagaaaataa
     5881 cctttgatcc taaccataag gagatgttgg aaattacgat gaaattcacg catgccgtgg
     5941 tacaacaatt gaatgagcaa tatcaaatag ccgtatccaa aacaaaggat acggctattt
     6001 ttgtgttaaa aacacccttt acgttaacga tctagtctag gttatatcaa acaacgttag
     6061 aggggcgcta acgcttctct agcgatttga aatcgttaga gaagtagtta gggaggtcct
     6121 tatcataaat agggatattt attaatgaat atttgaaata taattgtata taagaattaa
     6181 aaagagtggg gatagatatg aaaaagatgg gtaagtgtat tttatgtgaa aaatacactg
     6241 aacttactaa agaacatgta ccacctaaaa aatcagggaa tactggaggt aaaaagacca
     6301 gaactggtaa tttagatgat ttccttaaga gcgattttac aaaaggtgat tttccgaagg
     6361 ggattaaaag gaaacctcaa ggaaatgttt attata
//
LOCUS       DADVXK010000124         6377 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.126, whole genome shotgun sequence.
ACCESSION   DADVXK010000124 DADVXK010000000
VERSION     DADVXK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.126"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..194
                     /locus_tag="KB909_002536"
     CDS             <1..194
                     /locus_tag="KB909_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBB6838500.1"
                     /translation="NELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLGLVPVES
                     VEEVLGMKIEVEEDFQNHG"
     gene            187..336
                     /locus_tag="KB909_002537"
     CDS             187..336
                     /locus_tag="KB909_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBB6838501.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            490..1155
                     /locus_tag="KB909_002538"
     CDS             490..1155
                     /locus_tag="KB909_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6838502.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(1439..2524)
                     /gene="xerS"
                     /locus_tag="KB909_002539"
     CDS             complement(1439..2524)
                     /gene="xerS"
                     /locus_tag="KB909_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBB6838503.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            2858..3091
                     /locus_tag="KB909_002540"
     CDS             2858..3091
                     /locus_tag="KB909_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBB6838504.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            3088..3495
                     /locus_tag="KB909_002541"
     CDS             3088..3495
                     /locus_tag="KB909_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6838505.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(4632..5150)
                     /locus_tag="KB909_002542"
     CDS             complement(4632..5150)
                     /locus_tag="KB909_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBB6838506.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            6268..>6377
                     /locus_tag="KB909_002543"
     CDS             6268..>6377
                     /locus_tag="KB909_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838507.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT         2188 a          999 c         1037 g         2153 t
ORIGIN      
        1 aaaatgaatt aatgaaatta ggttatggga agtatcagtc tgagagaatc atacgacagg
       61 caaaagcaat tatggcttca aaaagctata cctattacga aaatagaaga ttaggactag
      121 tacctgttga atctgtagaa gaagttttag gtatgaagat agaggtagag gaggattttc
      181 agaatcatgg ttaattttaa aaaagataaa aatgggaaat atcattttac tgctagtttg
      241 ggattcgaca aacgaacagg gaaaagagta caaaaaaacg tagaggggtt aaaacagtta
      301 aagaagaaaa aaagcgtata ccgaacttgt ttctaattat ggaaaagaag cagaaacttc
      361 tcaaagtact atgttgtttg aggagttttt ttataaatta ttcctacctt attatcaagg
      421 gaaagtagaa gaaagaacat ataaaaatcg gttatctaca atcaaaaaaa cttttcttat
      481 ttctttaaaa tggagttaag agaaatacgt ccaattgaca ttcaaaagtg gcaaaataat
      541 ttattgagca aatataaaaa ttcttatgta agaaacatgt atgggatttt tcagatgtca
      601 ttagatcgag cagttgtttt gggactactt gaaaaaaatc ctgcaaaagt tattggaaat
      661 gtgaagaaaa ggaaaactac agttgatttt tggacaaaag aagaatttac aaaagttatt
      721 tcaacttttt atattgatga tttgtaccaa cattttggtt ttatttgtat gtggttactt
      781 tttatgaccg ttatgcgttt gggagaagcc actgcattaa cttggaaaga tattgatttt
      841 gaaaataaaa acttgcgtgt gaataaaaca ctctattata agagagccaa aacctatgag
      901 tttgtagaac ccgaaacggc ttctagtatt cgtacaatcg aactagacga caatacaatt
      961 acctttttaa aagcttggaa ggagcgtcaa gtttcaatag gaggcatgtc gtttgtactt
     1021 tcttataatg gaacacctac tcagaaatat acaatccgtc atattatgag aagacatgca
     1081 acgatcgttg gtgttcatat aatccgcata cacggattaa ggcatagtca tgcttctttg
     1141 cttatatcac aataaaaaga tgcacttcga attaaagaaa ggttaaaaca tgctgatgta
     1201 caaacgactt taggaactta tggtcatttg tatctaaatt cattgagaga gataacaaat
     1261 gatcccacag attatatcca aactaatttt tctaaaatca aaccgacacc tatttacgat
     1321 aataaaaaat aaatgataaa caaaagtagg atcacaccaa aagaaacaca ctagaaaaac
     1381 tataatacag gcttttctag cgtgttgttt cttatttccg cctatttata cattatactc
     1441 ataaagcatt taatgcatcg atcgtagccg cattgtctat atgggtatat aaagttgttg
     1501 tattggtact tgaatgtccc aattgttggg cagttaatac caatgaattt gtctgttggt
     1561 agagtctagt agctaatgta tgacgcagtt tgtgagggct gacttgaatt ctaaagcctt
     1621 ttgaatattt tgctaccatc cgttcgattg caataccgga tatacgcttg gcttctcctt
     1681 ggtaaattgc tagaaataaa gctttttcgt tttctgttac tttatatcgt tctttccgaa
     1741 tagctagata attagctaaa tattccattg cgaatgctgc tatattgaca gcatctcttt
     1801 tatttccttt tctagttact accacattat tcttatctaa agataggtca tctaaattaa
     1861 tatttataac ctcggagagt ctcaatccag atcctaaaat cagtgcattg atcgccaggt
     1921 ctctttctac atctcgttga taatagatca aagctcgttt actcaaagta tttttatatt
     1981 cattggcaat ataatctaga taattttgtg tatccttatc tagaaataat tttttctcaa
     2041 tggcattggc acgtgcagct aacgtagttt tatctgtgat ggttgctact tgatccatag
     2101 gattattgtc taagtatggt tttcctagag gattattgga acttttcgaa agatatttaa
     2161 atagaacctt taatgccgtg atatttctat tgatagtaga agtagataga cctaagttat
     2221 tattatcttt gagcttagtt tttgttgtct ctttttttac attttctttt gtgcgacgtt
     2281 tcaaatgaga tttgtacaag tttaggtcat aggcagttaa ctgtcttatc gaggtgatag
     2341 aagtatcagg aacgatagac tcactcagaa gccattcata aaagagctta taatttttta
     2401 gatattctaa agtggttcga ggtgattgat ctttatcctc acgatcttga acaaaatctt
     2461 ttatataatc gggcatatga agtatgattg tatctatttt ttgatatatt tctgtatttt
     2521 tcatgtcatt catcctttca ataagtaggg gagaagagta tctctataat tggactatac
     2581 caattataga atgttttgtc aattggtatg ctctaaaatt tattaatttg tttcaaaaaa
     2641 agcatataaa caggtatacg tttaataatt taaaataaat ggtatacata aatagggaag
     2701 gaaatagaag ggagcaatct aaattttttg aattttctta attaattata tagaaagaac
     2761 aatctttcta tagagttaga catgagaggg actatgcttg atttaaaatc aacaagcgta
     2821 tatactgtat atacaaagaa aaaggaggga gaagactatg gcaattaaag aaagaaaatt
     2881 tagggaagtg gggaactcag tagtattaac tatttcaaag gagtttctta aagaaaatgg
     2941 gttaaatccc ggagatacgg tttttttaga tgaagaaaaa cttcgagcgg caattacaaa
     3001 aaaacaagcc ttatctgatg aaattgattt agcaatatct caagcattaa ctgaatatga
     3061 tactactttt agagagcttg tcgataaatg agtattcatt acctagaagc caaagatatt
     3121 ataaaaatga atgtaatcca aataaaaaaa tactctccta atgaacccct tggtgtaaag
     3181 gatgcgaatg ctttagaaat gtgtgtaggg caacttcgag cctcagcttt tggtgaagag
     3241 gtttatcctt cgatttatga aaaagcagct atcctactta tacaattgat aaagaaacat
     3301 ccttttcaca atgcaaataa acgtactgct ttcttagcta cttttgtctt tttgaaaatc
     3361 aatggacagc ttttagctat tgatcaaaaa gatgctgtaa atttagcggt atatattgct
     3421 acgtatgata aggatttcga tcaactaaaa tatgaagtga tcaacactat aaagacacat
     3481 acgcagccca tttaaggagt tactgtatgt gtctttatag ggttattagc tgctatagcg
     3541 aaataattga agtaaattac aaatagctat aattcaaatc caactatata gaaaacgtaa
     3601 attttctata tagttggatt aagataacga ctatttattt tatcatattt ttactatacc
     3661 ctatactttt acttggtata tttatgaata atcgcaaatt tacccctata ctactagttt
     3721 gtaagttaga ttaataaaaa tactaaagtt atttgttctt ttattaaata cacctacaac
     3781 ttataaattg atggtattta gataacacga aagaataaaa ataacagctg atagtaaagt
     3841 ttgttgacga ttgctactca atcgaaagtg agttagtgcg tatgaacttg cttctgaaaa
     3901 cttatgaaat gaaagacctt ttacatcttg cagaaatcgt tactgggatt aaactaagca
     3961 ataaaaacta atgttcccct cattctttga acttctacta tttgatttat ttattctgat
     4021 aaatgacgat ttcaccttca ggatcttcaa atcccgtata gaatttattt aagatctctt
     4081 cagtatcagt aataggatag gcgataggcc acataccctt tgatggttag aataaactgc
     4141 tcaaaatctg tatcgtatgt tggctttagc atattaacaa aggctatctc caaattataa
     4201 accataagcg ttgaatcgtt cttaacaatt tcaattcttc ctaacccaaa gtcagaagat
     4261 ataattaccg gacttgcctt acccttcatg tgggttgttg agattccata tttaaaggga
     4321 attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa taaaaaaatc tttcccctgc
     4381 tagtctccta agtccctttg tagcggatat ggcaccataa tctcatttta tcgaagtgag
     4441 tcatggttta tctgttggcc aaccaaaatt gatacaatct aacgatgcac cctctacggc
     4501 attctagggg agtgcacttg cattcaccca ataaaaaccg gcagttagca aagaacttat
     4561 gtagtcgtat gttcttactg ttaacataca agaggtctcc tttccacaat tgcttagcag
     4621 taaacgggaa tttacaaagc taatctcttc cattttctta tctttgttct aaaagtccca
     4681 aatggagcaa ctgtatttac atgaataaat ttatatactt cccatacagc cgttttggtt
     4741 gcctcgtctg cccattttct tttgtgtgca gtgaatagat cttcatcact cattgaatca
     4801 atcatcatgt taatatcatc aatattacga ttgagaattt cctctaattc tttcaatggt
     4861 agatgtgcat aggtatttgt aaaccactta tataactctc ctaactgatt ccatttaaat
     4921 tgatcagaag gcgttttaac agataatcca tttctttcat cattttccca ttttagaatt
     4981 aaattcgtcc aaccaacttg atatgctaaa ttttcagcag gtgttctatc cacttcctca
     5041 actcttttat ccttcaattc ttcaggaata gtttcaaatt ctaaaatata tttagtataa
     5101 gtcctattta tttctttttt taattcttct ttatttttat atgttctcat tatattacct
     5161 ccataaattc ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc
     5221 cgttctacaa tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata
     5281 aaatatccca acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg
     5341 aatatatttc ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc
     5401 aaaatcatgt taactactat caattactaa taaaaactac cactttaagc gttaagaact
     5461 gttaagttta gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg
     5521 taaaactcaa aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg
     5581 gtaaaaaata ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga
     5641 aacagctaca aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc
     5701 catattcacg cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt
     5761 tttaggaaat tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt
     5821 caccagatat tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc
     5881 accgcgaatt tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa
     5941 ttaagggatc aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt
     6001 aaacaattat agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga
     6061 ctttcttatt ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt
     6121 tacgagtact attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac
     6181 ccccacttag cttggatagg ctacaattaa ctagacagaa aaattaaggt gtgtagacta
     6241 gaagaaaaca taccaggagg aatttttatg tctaagagaa cacgaagaac tttttcacaa
     6301 gaattcaagc aacaaatcgt caatctttac ttagctggaa agccacgtgt agaaatcatt
     6361 cgagaatatg aactaac
//
LOCUS       DADVXK010000125         6324 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.127, whole genome shotgun sequence.
ACCESSION   DADVXK010000125 DADVXK010000000
VERSION     DADVXK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.127"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..270)
                     /locus_tag="KB909_002544"
     CDS             complement(<1..270)
                     /locus_tag="KB909_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838508.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYF"
     gene            complement(478..1404)
                     /gene="glsA"
                     /locus_tag="KB909_002545"
     CDS             complement(478..1404)
                     /gene="glsA"
                     /locus_tag="KB909_002545"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBB6838509.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(1427..2854)
                     /locus_tag="KB909_002546"
     CDS             complement(1427..2854)
                     /locus_tag="KB909_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838510.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(2885..4099)
                     /locus_tag="KB909_002547"
     CDS             complement(2885..4099)
                     /locus_tag="KB909_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBB6838511.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(4440..4682)
                     /locus_tag="KB909_002548"
     CDS             complement(4440..4682)
                     /locus_tag="KB909_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6838512.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4714..5271)
                     /locus_tag="KB909_002549"
     CDS             complement(4714..5271)
                     /locus_tag="KB909_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6838513.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(5284..5472)
                     /locus_tag="KB909_002550"
     CDS             complement(5284..5472)
                     /locus_tag="KB909_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6838514.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5485..6051)
                     /gene="amaP"
                     /locus_tag="KB909_002551"
     CDS             complement(5485..6051)
                     /gene="amaP"
                     /locus_tag="KB909_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6838515.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         1906 a         1324 c         1078 g         2016 t
ORIGIN      
        1 aaaataagat tgaccgtaca gaaactgtgt gagctcagaa agagcaatac catgtttgaa
       61 tacgagttta tacttatgct tctctcttac ttgttctttt atacaatatt ctagacactc
      121 ggctagactt tctagatcgt gaaggatcgt tggtgtagtc acccttagag aaatagctgt
      181 ttgttcgatg tctatttctt ggaattcaaa taattgttca cacagataca cttttctaaa
      241 tatatttcgc tcgatgtaat tttccagcat tcctgataca cgcctccagt ttttcttatg
      301 attttattta atcatatctg taaatcgtat ttttgtttcc tttttattta gaaaagccct
      361 ttcaaaaacc aataaaaaaa gaaactggga caaaagtcaa acaagctcac aatttcagcc
      421 tcattgtagg tagctttgag ccgtttggac ttttacccca gcctctttca agaatggtta
      481 ttcaaagatg tcagcgtcta gttctttgac tacatctttc aacaattgga taccagctgc
      541 gctgttacca aatggatcta gtgccgggct gaagacacct atgccgtaac gatttggcac
      601 agctgccatc aacccgccgc ctacaccgct ttttgcaggt acaccaacat ggacggaaaa
      661 ctctcctgat tcatcataca aaccagcagt tgtcataatt gatttgacga ttgtagcact
      721 ttcttcagta atgatttgtt tgccattcca aggagcaatt cctttatttg ccagcacagc
      781 agctaatttt gctatgcctg tagcggtgac attgagggag cattgtctga aataagcatc
      841 gagtatctcc ggtacgtctc cttcgatcat ttgattacct ttcatatagt aagcaagaga
      901 gcgattgata tcacctgttc ttgattcaga atgatagatt tcttcattca atgtgatatt
      961 aggatcatca cagatctctt tcataaatga caagattcgc tcaaattttt catctgcatc
     1021 tttaccggca atcaacgagg ttgttgcaat cgctcctgca ttaacaaaag gattcattgg
     1081 atgtttgcga tgattgattt ccatattcat gatagaattg aaggcaaaac cggttggttc
     1141 cgtgttgatt gtttgaaaga ctttttctat tccgttgtct ttgattgcta ataacaatac
     1201 gggaactttt gacatgcttt cgatggcaaa gcgcacatcg gcgtctcctc cctcaatcag
     1261 ttgttttgta tccaaatcat aaatcgccat acctaattgt ttgggatcca cttcagctaa
     1321 tgctggaatg taatccgcca cttgtcctgt ttgataatag tggaaatttt ttccaatcaa
     1381 ttgttctaat tcttttactt ccatttgaat aaccagcttt cattttttat ttttctgcat
     1441 gctggaattt atgacggcat gcgtagatcg taaatggaat aactaagacg ataagataag
     1501 aaacaatcag aatcgtttca taaatcccat gctgtccagc tgcgatacta gcaggtggaa
     1561 caaatgagat acaaaaagca aaaagtgaag tcaaaagacc taaacaagca acgattactt
     1621 ttacaacttt tccgcctgga acctgatagg ctctttcaag actgtcatct ttaaaaacca
     1681 gcttcaaata gcccgcgaaa aacataaagt acaacatcag gtagattaca acagtcaatg
     1741 acatcgctgc aagaaatgaa agattattcc ccccgccgct taatgtaaag acggctgccc
     1801 agattgttgc aacgatccca tttgcgatca tcaaatgagc aggaacaccg tgtgtgtttt
     1861 cttttgcaaa atattcagga agtaatcctt cttctgctgc tacgtgaagt gcttttgaag
     1921 gagaggttac ccaagaagca atttctccga tgacacctaa acaaacaaga atcgcaagaa
     1981 ttttcgcaat ccatgcaaga tttggatcaa tgtgtcttaa taggaattct aacgattgaa
     2041 tcacccctgt attaagagac aaaccatgtt gaggtactgt agtagcgacg gtcaatccgc
     2101 caaaagtatc taaaatgatt gccagaataa ccaatacaaa cattgctaat ggataatcct
     2161 ttttagggtt ttccatttca tttgcatgac tggcagatgt ttctacgccc atatatgcta
     2221 aaataaagga aacaaaaaca accagcgtag gcaatttcga aaaatcagga atcaatgttt
     2281 tcatagacag tatcgtttgt agtggagcgc ctgaagcgac ataatggatc cctaagccaa
     2341 acaagactaa tgctggcaac aagataccag ctacaaaacc gatccgagca atcaatgaag
     2401 tgtatttggt tccttttaac tgtgagagta aaatagccca gaaaataatc aataggattg
     2461 ccaatttcag atatttattg ttttgtatag caccaatacc cgttgcatag gataatgcac
     2521 cagttaagaa atacagcatg gtcaagtagc caactgttat ctcaaaccat tggaaaaaga
     2581 ttgcggcaaa accgaatcgt tttcccaatg tgcgactgac ccaagtatag acaccgcctt
     2641 tttcccatcc tttcaccgtt gccatctctg ctgcgcacaa tgccacaggg ataaaccata
     2701 gcaaaccgcc taataacaag aaaaatacta agctgaagcc tgaggtcgcg aatgtgggat
     2761 attcatataa tgaaacgacc attgagatgg tcatagccaa aaagccaaag aacgttaatt
     2821 tttttgcagg aattttcgtt ttgctttgtt gcatgaatct tcctcttttc tatttgaatt
     2881 tgtttcaatt gagtttgttg ccaaagaaga aaaagtccaa tccttcttct tgttcttctt
     2941 ttgtagtagt gatcgttgta aagtgcatcg ccgattttaa aatcactgtt gtcagcacat
     3001 aggcatacac ggcagtaatg atgacaccaa tcacttgaat ccctaagaag taccagctgc
     3061 ttggattcgt tagtaaatgg ctgttagatg caaagatccc tatcagaatc gtacctgtga
     3121 atccgcccat gccatgaaca ccccacacat caagtgcatc atcccattgt ttctttttac
     3181 gaaaatcaac agcagcatga cagacgatac ccgcaatgat cccaatcagc atggcacttt
     3241 ttgcttctac ataaccggca caaggcgtaa tggctgccaa tccagcaacg gatcctgtta
     3301 gtacgtcgac aaaatcaaag ccatttcctt ttacttttgc aatgatcagc caagtaatca
     3361 tcgcaaatgc aagagcgatg aatgttgaac caaatgcatt gactgcttgt tcatctgctc
     3421 gaagtgcacc accggaatta aaaccgaacc agccaaacca aagcagtcct gtaccgatag
     3481 cagctgccat aagactgcta tgctgacttc tttctcctaa aggaatcttt ctttgaccaa
     3541 gtgtgaggat acatgctaaa gagccgaatc cagctgtcgt gtggatgact gctccaccag
     3601 cgaaatctct aaatcccatc tgatccaaaa atccgccacc ccatatccag tggcaaacag
     3661 ggaaataaat cagcagattc caaaaaataa caagtataat atagcctttt aaattcaatc
     3721 tccctgcaaa agctcctgtc atcaaaggaa cggtaatcac gataaacatc agttggtaaa
     3781 gaaagaacat taaaaatgga atcgttgcac catgaaacat gttggggaag cttgtaacat
     3841 gtctcatcaa aaagaaatct gccgggtttc caataacacc gccgatatcc cgtccaaagg
     3901 ccaatccgaa tccaccaaat acccacataa tcgttgttat cccaacggag agaaaagatt
     3961 gagacatgat cgttagtata ttattcttcc gtgctaatcc gccgtaaaaa aaagctagac
     4021 caggagtcat caggcaaacc attgctgtac ataaaatcat gaatgctgta tctcctgtat
     4081 tgataggtaa tgtattcatt tttttcgcct cctttctacg attacgagta taaaagaagg
     4141 tgtagttgtt tttttcttct gtttttttga attaatactt gcatttataa aagacagaca
     4201 attaataaaa gcttgatgtg ttgtgctctt tttcgttttt cacacaaata aagacaaaaa
     4261 ataaacggtc ttctttttat agaaaaccgt ttattttcgt ctttttttat ttttaaagat
     4321 attttttcat aaggaataaa gaatacttca tataaaatat ataaaaaaga accgcagcga
     4381 gtgtcgctac ggttctcaaa tttgttcttc atttcaacat aagtttttct tcaatttgct
     4441 tataatttac gtgcaaagaa tgaaacgact aatactaaaa tgattgcacc gatcaatgat
     4501 ggaatgatag ccattcctgc aattgttggt ccccaagttc ctagtaaagc ttgtccaatt
     4561 gctgaaccta ctaaaccagc aatgatgttt gcgatgatcc ccattgatga tcctttattc
     4621 gtgattgctc ctgcaattgc tccaatgata ccgccgacga ttaatgccca aataaatccc
     4681 attttaaatt cctcctaact gacttcttac ttcttattgt acacgtggtt cgttattttc
     4741 tttgactttt tgtgcacctt tgcctacagc agattttgct ttatctgttt ggcgtgaagc
     4801 aaattgtcct gtggattttg ctgcttctgt tactttgtct tgtactgttt cttgatcttt
     4861 ttggtattct tcttgtgttt tgatgtctgc aacattcaca ttcacttcga taacatctaa
     4921 atgtgtcata ttgtttactt cagtactgat caattctttg atttggttgt aaatatcttc
     4981 gatgtcttta ccgtattcta cgatcacatc tagatccaca gctacttgtt tcttacctac
     5041 ttctgtattg atacctgctg ttacgttatc tgtgttgact aatttttcag ccatatttga
     5101 gaaaaatccg ccatctaatg tcaatagacc atctacatct ttcaatgcat aaccgatgat
     5161 tttttggatg actttgtctt cataagtcaa ttcaccattc atcatgcggt tttctccttt
     5221 ttcatttgcc aaaactgatc catttgttgt attcatgttt ttgttttcca tctttgtttc
     5281 ctcctatgat ttaaaaaatt gatcaactat tcctgactgt ttcaaataaa aaccgattcc
     5341 tgcgccaatt gctgtcatga ttatgatcaa caatgtcttg aaaaatccaa tcgttaacca
     5401 taaaacagct agcagtagtc caagaccccc aaagataata gggagcttgt atgctgaaaa
     5461 tagttctttc attatttggc cctcctattc cactcgagag tgcttgtagt ctcttgtatc
     5521 ttcttgttct tcataaccgc tgtatgtgac tgccactttg accgtttctt ttgttccgag
     5581 tactttagtt acttcttctt cgatatcttg catcaataca cctgttttcc ctactaatga
     5641 agaagttcgt ttcaagtctc cgttgacatg gatatggatt cgatttttcg ttgaacgtat
     5701 ccgtacttta ggtgaatgaa tgaactcttc ttcgtgtaaa tgggaacgta ccaacccttc
     5761 gatcgctttt ttgtcgattg ttagtttgcc atcttcccgt ttcataacga aagttcctct
     5821 tgactttgga tagaaaagaa cgactagcaa gatgataata gcaagaacgg caaatactac
     5881 agctgcccag aaaatatatt gttgcatgta gtaattcgtt aaagtaaaga agcgaaatcg
     5941 ttccaattgt tcaggcataa tatacggcgc attgatcaac gcaatcgcta gaaatactga
     6001 aagtagcagt aaactcatga taacaccgat tatttttaac cccttattca ttttccacct
     6061 cctataaact tatttttacc ctgtaaataa ctctaccgac aatcacagta tagatagcga
     6121 acagttagca tagcatcagt aaataaagcg ctaccaaaca ttgctggatc ataacggcgt
     6181 tttattgcca gtctgatact gaaataacaa ttgcttactt attctctatt tacttttgat
     6241 tgctggctat acttaaagga tattattcaa gattaaaaat tgcaaagatt atgctcagtt
     6301 attattacaa gattctattt attt
//
LOCUS       DADVXK010000126         6267 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.128, whole genome shotgun sequence.
ACCESSION   DADVXK010000126 DADVXK010000000
VERSION     DADVXK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.128"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(41..229)
                     /locus_tag="KB909_002552"
     CDS             complement(41..229)
                     /locus_tag="KB909_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBB6838516.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="KB909_002553"
     CDS             499..861
                     /locus_tag="KB909_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6838517.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="KB909_002554"
     CDS             913..2595
                     /locus_tag="KB909_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBB6838518.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="KB909_002555"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="KB909_002555"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBB6838519.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="KB909_002556"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="KB909_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBB6838520.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="KB909_002557"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="KB909_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6838521.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT         2080 a         1092 c         1430 g         1665 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcga
//
LOCUS       DADVXK010000127         6173 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.129, whole genome shotgun sequence.
ACCESSION   DADVXK010000127 DADVXK010000000
VERSION     DADVXK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.129"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            725..811
                     /locus_tag="KB909_002558"
     CDS             725..811
                     /locus_tag="KB909_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6838522.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="KB909_002559"
     CDS             complement(932..1621)
                     /locus_tag="KB909_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838523.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="KB909_002560"
     CDS             complement(1866..2780)
                     /locus_tag="KB909_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6838524.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="KB909_002561"
     CDS             complement(2762..3142)
                     /locus_tag="KB909_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBB6838525.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="KB909_002562"
     CDS             complement(3592..3879)
                     /locus_tag="KB909_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6838526.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="KB909_002563"
     CDS             complement(3899..4123)
                     /locus_tag="KB909_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBB6838527.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="KB909_002564"
     CDS             complement(4578..4748)
                     /locus_tag="KB909_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838528.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="KB909_002565"
     CDS             complement(4763..5296)
                     /locus_tag="KB909_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6838529.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="KB909_002566"
     CDS             complement(5317..6159)
                     /locus_tag="KB909_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6838530.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DADVXK010000128         6124 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.130, whole genome shotgun sequence.
ACCESSION   DADVXK010000128 DADVXK010000000
VERSION     DADVXK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.130"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            67..912
                     /locus_tag="KB909_002567"
     CDS             67..912
                     /locus_tag="KB909_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6838531.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1193..2413
                     /locus_tag="KB909_002568"
     CDS             1193..2413
                     /locus_tag="KB909_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBB6838532.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2410..5130
                     /locus_tag="KB909_002569"
     CDS             2410..5130
                     /locus_tag="KB909_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6838533.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5114..6058
                     /locus_tag="KB909_002570"
     CDS             5114..6058
                     /locus_tag="KB909_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6838534.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2286 a          961 c         1197 g         1680 t
ORIGIN      
        1 gtatatgttt tgtgagaaat ttagacttac aataagcagt gaatttataa tcaacgtata
       61 ggagacatgg atgaaatgaa actaattggt atagatttag acggtactct tttgaattct
      121 gaccagagca ttagtcaaaa aaatgcaaga acaatgaaac atttaccgga agactgtttt
      181 ccattcattt gttctggaag agaagtagaa gacattaata atattctcaa aaaatctggt
      241 ttaaggatac cagcagtagg gttaaatggt tctgttggat ttgatggaga aaaaaagata
      301 tttgagtctt ccttcgataa aaatgatgta aaaaaaattg attctgtcct atcgaaattt
      361 ccaaccaaaa tatatacaaa tctcggaagt tatgaatctc agaattataa aaataaaatg
      421 aaaaaaattt ttcacgaggt agggagtgaa ttttctatca aagagctaaa ctatgagctt
      481 gagtatgaaa aatctatttg ttcaatccct tataataata ttgaggaaat tatagaaaag
      541 gatgctatca gcatttacaa attttttatt tttattccta atcgtcaatt gaaagctaat
      601 atatttaacc atttgaaaaa gatgctaaat gtgtctgtta ctgaatcggc acctgtaaat
      661 attgaaatcg tacctcaaaa tgtatctaaa ggtgtggtgt ttgatcgttt ggaatcaatc
      721 tacaatttaa agaaaccttt gagaatcgcg atcggagata gtttaaatga cttatctatg
      781 tttgaaagtg cagatattag ttttgcaatg ggaaatagtc atcaagaaat catgaaaaaa
      841 gctgattatg tcactgtttc aaatgataaa gacggagtat ctcaagcatt tgaaagaatt
      901 cttaccatat aaactaatta aggtagtata gaacatagaa ttctaaatac ggaaaaatgg
      961 agcataaatt ccagtacaaa tagtacttct tcagtgtcaa acgaagcgaa tataacatag
     1021 atatttagga ttgtgacaaa aatcatgtca caatcttttt ttcgaataaa cttatttttt
     1081 gaagtcggcc atttatcgta atttctttgc ataatacgaa caaattttcg gttattgatg
     1141 aaaaaaaaca ttgaaaatgg tatgataaaa gaaaaaaagg aggaaatttt taatggtgaa
     1201 atttatccat gcggcagatt tacatatgga tcggtcattt gaaggactga caactcttga
     1261 taaaactgta caggaaaaac tattgaagac gaatctgacc gttttatcaa atatcattga
     1321 acaggcaata ataaataacg ttgattttgt tttacttgca ggagataatt ttcatcaaaa
     1381 tcgtccttca ttaaaaatac agaaacattt ttcagaacag atgaaacggt tagaaaagaa
     1441 ccatatacct gtatttataa tattcggaaa tcatgatttc tatcaaaaag agcggtattg
     1501 gttctccttt cctaaaaatg tccatttatt tacatccgaa acggtagaga caaaaaaaat
     1561 aacgataaaa agtggagaaa ctgtctctct cagtggattt agttatcgtc aaccgtggat
     1621 tcaaaaagac aaagtgatgg aatttccttc tagagaactc acagattacc atattgggtt
     1681 gtaccacggg gaacctggcg tctctcaaaa aggaaactat gctcctttcc aaccctcaaa
     1741 gatgcaagaa aagggatacg attattgggc tttagggcat atccatgtgc caacggtctt
     1801 aaatgaaaag caaacaattg tttatccagg tgcgcctcaa ggtcatacta aaaaggaaca
     1861 agcttctaca tctattctac tagttgaatt aagtaaagga agttgccaaa tacatccgat
     1921 taaagtagca gaggtctatt ggaagacaaa ggaaatatca ttgaggaaag caagaacgac
     1981 aaaagaggtc attgttcaca ttcgtcagca gctttcaaaa gtagaggatg gatttagttt
     2041 aattgagata aaattaaaag attatgacca tctcaataca gatgttttgg aacggataca
     2101 atcaggagag ctattagact atttgttaga ggaattctca gataggataa atgatttctt
     2161 tatttggcgt atttctctca tagagaatac tttttatacg aagaccccac ttgctgcttc
     2221 tgctaaattg atggaacagt tatttcaata ctatcagaca cctcaagatt tccaacaaat
     2281 tttaaatgaa gtatatagtc atcaagaagc ggctagaata ttgagcgaac tgccggaata
     2341 tcaagaagaa acacttgaaa aagccaagca gctgcttaat caagattttt tatttgagga
     2401 ggatcaggaa tgaagatttt aaggatcgag attgctgctt ttggaaaatg gcgtcaaaaa
     2461 agttttgact tttattcagg caatcagctg atctatgggg gaaacgaagc aggaaaatca
     2521 acgatttatc aatttattca agcaatatta tttggtttcc cttcaaaagg ccgtaaaaaa
     2581 aaggattata caccaaaaga cggctcagcc tatggcggca aaatatggct taaacatcct
     2641 gtatatggtg aatttgctgt cgagcgctac aagcagcaaa atcgcggaaa atcgaaggtg
     2701 tggctggggg atcaagtggg aagtgatgag ttactagaaa aactgatcgc acctttgacg
     2761 aaagagttat tccagcaggt atttactttc cagcaagagc agttgatgga actagatcat
     2821 ttgagagaaa aagagctaca tgatgcgctg atttctttag gcatcacggg cagttctcaa
     2881 gtattccaaa agcggcaaga atattatcag aaagcacaac aattattcaa gaaaaaaggc
     2941 caaaaattac taatcaatca aaaattaaat gaatggaaag agctgcaaga aaaaattcat
     3001 caaaaacaag aacaggaagc ttattttggc aagttgatcc aacaagaaca ggaatacgag
     3061 tcgcaacagc agcagttatt ggcacaatta aaagaggcga acaaacaatt ttcattagcc
     3121 agacagcaag aacttaattt ttctttatat gaagaatggc aatctctcaa aaaaaacagc
     3181 actacaggtc ttcctgatga gcaacttctt ttagatctgg agtctttctc caaacggtat
     3241 cagcaaacaa atgagcgttt ggaagaatta gaagcaacac tggaaaagca tagcgggatg
     3301 gatcagcagt cagccagata ttatttttat ttagagcagg agcaggaact aaaagatctc
     3361 cagcaacttc aatttacagc ggaacaatta aacgaagaat ggcaaagatt acaaattgag
     3421 actagagaaa caaattcaga attgaagatt ttggaacaaa ggtggcattg gcagaaaaat
     3481 ccgttaccgg aagaattttt atatgaagaa gaatggaagc atcttctggc tgaagaaaga
     3541 aggattgctg atctagaaag ccagatttct gtgcgtctcc aaatagctaa agaacagcaa
     3601 gagatgattg aagcagaagt gaatgacttg gaagagacct atccagcatt attacaaaat
     3661 cagtcagaga tagcaccagt ctcttcatct aaaccgtata tgctgatggc tggcggagca
     3721 ataatcattg caggtatatt tgtaccaatg cccttgaaag tgatcctttt actaattggt
     3781 gcaggcatga ttggctattt cttctacaaa aggcaaccaa aaattaaaac taaaaatgat
     3841 ttctctgaga taaaaggaat gtggcaagaa aaactaggac aacttgatct agccttagct
     3901 caattagctg aagcagaaga aaaacaaaag agaactggag aagaaaaaca gattcttcag
     3961 caagaagtat atcgttttgc ggatcatcgg cacttaggaa agatggatac gctcaaactc
     4021 atgaaagaat atggacagga agtcatagat tatcagaaat tatatggcgt atttgagcgg
     4081 aaacataaaa gagaacagga aatacaagaa aaactacgac aaatcgacca aaaatttgag
     4141 tttgttaaag aatggttacc gatacaagat aagacaattt cagaaaaaat ggtattgctt
     4201 tcccgtttta tacaagagat ggaacagatg aaatttgcca gaagctatca gcaaaatact
     4261 ttattgaagc aagaaatcaa tcaattgaaa aagaaacaaa aagtatggat acaagaatac
     4321 agcgaacaat tgactcaagc aggcttatct tatccttcgg aagtacctgt ctttttacaa
     4381 aaagccaaac aagccgaaca gcagatgaaa agatacaatg aattatcgga aatgcttact
     4441 ccactatttc ctgaagagct gacaaaagag aaattatctg taagactgcg ccaactgaaa
     4501 gaaaagcaat cccaactcca gcaagaagaa aaagaagcaa gtgaaaatcg gcaacgactc
     4561 caacttcaag tagaagagtt gcaaagagac ggcacattgg acgaacttta tcaacaagct
     4621 agccggcaaa aagcaaaatt acaggaatta ctggaggaat ggggagcact tgaaatcgcc
     4681 gggacattct taggtgatct ttcaacagag atgagtgaaa gacaattacc ccagttgtta
     4741 agagcagcag gtgattattt aggtatttta acaaaaggaa attatcagaa gatattactg
     4801 aaaaatgata cactgacttt aacagacgga tatacagaat ttcccatcta tgagttatct
     4861 acaggtacga aagatcagct gattatggcg atgagatttg cttacctctc attagaagct
     4921 aaccgttcga tatgcccgat catcattgat gatggctggc ttcattatga tcatcagcga
     4981 aagtatcaat tagctgaact tttagctaaa tttggagaaa agtatcaaat aatttgtttt
     5041 tcttctgata aagaaatggt aagctattac catgagatga accaaatcgt aaaacaatta
     5101 gaaggagcaa ataatgaaaa aaattcgtga tttagtaatc gatgagcagt ttgaacaatt
     5161 tgtcctgatc aaaagtgcag atgtaagaat cgctaaaaac ggaaaaaaat ttattgcttt
     5221 tactttccaa gatacttcag gtactatcga tggtaaatac tgggatgctt cggaggagga
     5281 aatcaataaa tttacagccg gcacagtcgt ttttctaaac ggtaaaagag aggtttatca
     5341 aggaaaccct caagtaaaga ttcttcatat gcgcttaaca agggtagatg agccaggaga
     5401 gcctagttta tacatggaaa gagccccttt gaagaaagaa gaaatggaag aagaaatcaa
     5461 tcaattgttg tttgagatca ccaatgcgca ttggaatcgt attgttcgct atctacttaa
     5521 taaatatcaa aaacaatttt ttgagtttcc ggcagcaaaa agaaaccatc atgcatttgc
     5581 cagtggatta gcttatcata ctttgacaat gcttcactta gggaaatcaa tcgccgatga
     5641 atatcctgag ctgaatcgag cattgttgta tgctggtatc attttgcatg atttaggaaa
     5701 ggtgattgaa ctttccggtc ctatgtcgac agaatatacg cttgcaggaa atttgatcgg
     5761 tcatctggta ttgattgacg aagaaataac taaagcctgt cttgcgttga aaatcagcga
     5821 agctgacgaa gatgttctcg tattacgtca tatggtttta gcacaccatg gcttattaga
     5881 atatggctca cctgtacgtc caagaataat ggaagcagaa atattacatc aaatcgacaa
     5941 tatcgatgct tcgatgcaga tgatgttgac ttcgattcgt caaacagaac caggaaaata
     6001 caccgatcgg attttcggta tggacaaccg aagtttctat gtaccaaaag atttatagca
     6061 aaaatttatt tttttcattc aaaacaaaaa aagcgagaca taagtcttcg ctttttttgt
     6121 tttc
//
LOCUS       DADVXK010000129         5939 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.131, whole genome shotgun sequence.
ACCESSION   DADVXK010000129 DADVXK010000000
VERSION     DADVXK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.131"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(489..992)
                     /locus_tag="KB909_002571"
     CDS             complement(489..992)
                     /locus_tag="KB909_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6838535.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1351..2376
                     /locus_tag="KB909_002572"
     CDS             1351..2376
                     /locus_tag="KB909_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6838536.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2699..3577
                     /locus_tag="KB909_002573"
                     /pseudo
     CDS             2699..3577
                     /locus_tag="KB909_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
     gene            4053..4169
                     /locus_tag="KB909_002574"
     CDS             4053..4169
                     /locus_tag="KB909_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6838537.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5097..5435
                     /locus_tag="KB909_002575"
     CDS             5097..5435
                     /locus_tag="KB909_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838538.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5529..5759
                     /locus_tag="KB909_002576"
     CDS             5529..5759
                     /locus_tag="KB909_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838539.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT         2020 a          892 c         1087 g         1940 t
ORIGIN      
        1 acttaaaaaa taacgacaca gaaaataccg tgtctcagat ttctctacta cttctaaaaa
       61 ctactgtttt tttcctttga aatgccttca aaaagtagga tcaggcagaa tatactggca
      121 gaatcaagga gaagggagcc taaataagga gaaaaaccat agaaaatata aagtaattac
      181 ttataaaaca agctttttat agaaaaataa tatacctgag tagggtataa attaagacgg
      241 aattcctttc tagattgaga tattgactag gaagaatgtt aagattttaa gcctttaagc
      301 taaaaaaaaa ccctttttgt taaataaggg gaatatagcc tgtcagtttc aaactgcaag
      361 tcgtcctgct gcaataatat agtagattag agatgaaaat agattttttt aaaccaatga
      421 ctgaataaaa agaccgtcat agatacacat tggaatgtgt ctattacggt ctttttttac
      481 gaacgatttt attgaagacg gacagttcgg gtcaaaaata aaaaagctac gatcagaaat
      541 aagaataaaa tgtatcccaa aataatggct agacggtcta acttatttgt cgatagatgt
      601 ttgtttagaa gttgataggc ccataaacct atcagtcctc ctgttgtatt agttatcaaa
      661 tcagtgatgt ccgctacgcc aataccgaat aggaattgaa tcaattctgc caagaagctt
      721 acaaggaaaa taatccctaa ttttttagaa aaagaaagtc tcttgaaatt gacattcaaa
      781 agcaccccaa aaggaaaaaa gacaatcaag ttataagtgg tctcacgtaa taccgtcgta
      841 ttttcaaaag aaaaagtaga aaaagggacg agattgacat tgctgtaaga ataagtgaga
      901 aattgtggaa gattaaatga tagcttgaat aaaatcaacc ataatagaaa gaataaataa
      961 atccctaata aaaattttga tacataccgc atagacatct cctccattta aaaagtatac
     1021 catcgaaaac cgctgaaaaa tcataaaaaa gtatgaagtt taaggaccaa cgtagttatc
     1081 gtacgaaaat tagaagcttt tttttgttgg gaatccggtt tctttaacaa agctaagata
     1141 gcgagttgct tggaaaagtt gctatctttt ttctgtcaaa acgactcgga atgttcgttt
     1201 tttgttctaa tttctccaag ttgtttactt tttgatacta agtttatgaa aaatcaagaa
     1261 atagttgtta tactaggtaa tgctgacaaa cgggattggc atttcatctt ggttcagctt
     1321 tttttccaat tactaggaag gagggataga ttgttcaaga cttattttcg tttcaataaa
     1381 atacaagata atccttttcg tatcatgaat ctgatgctac ttatctttat tgtattatgg
     1441 ttaggttaca taaatcatga ttttttgatt tcaagttttt catcattagg gatctttact
     1501 tttttctatt atcaaaacat accgatgaaa tatttgctga aacgtatgtt tctgatcggt
     1561 tgcggactgt tggttgcttt cgttttgggg atcttatcga cttatgtttt atggcttgaa
     1621 ccatttgccg tagctttggt tgctttttcc agcagattcg tgttgcgatt attccatatt
     1681 tctaaaccag gtggcttgtt ttttgcgatg ctttctgcca tgggaacgag catgcagctg
     1741 ccaatcgctc aattaccgat cgtctcactt tattttttta tgggtgtcgt ttttgccctg
     1801 attgcggcag tgattacaaa attactggat tcacggcctg agcagacaat tgaaaaagca
     1861 actttaaaag aaagatttca cgaagagcct ttagtgatca ttgattctgt tttctacagc
     1921 gctgccttat ttctttccgt ttatgtcagt cacggcttga atctgcataa tccttattgg
     1981 ttgaccttgt catgtgcatc gattttgcta gcagaaaact tggatgcgat gaagcatcga
     2041 caagtccaat atctgattgg atcgatgggt gggttatgtg tgtcggcatt cttgtcattt
     2101 gtgccgttta cgcagttgca gaccattttt ctgatcactt ttctatatgg aatcgcacaa
     2161 tttctagttg ctagaaatta tgcagttgct aatatttttc ttaatccgat ggcgttgatg
     2221 ctatctacac ttattcgtgg agcatacttg atttctttga tcgaatatcg ttttttaggg
     2281 atcgtcatag gaagtttcat cggtttaggt gttgcgtggg taatgacggt tggtttgcaa
     2341 cattatttaa cggttgttcg tcaaaaatta gaatagaagg acaaatatat gtgccaaaag
     2401 aggttatgac aagatttttg tcacaacctc taattcaagg tgttcaaaag ccagattctc
     2461 agcattaagt caaattcaca caaaaatgtg gaaaggaact ttcaaaaaaa ttttatattt
     2521 attctatcaa aaaattttgt ttatgatggt aactgaataa actttcctga gatggtcaat
     2581 gctttccttg aaagtcttac agatattctt tcttcataga aagtttaagt tttatagtta
     2641 gtgtacaata aaagtatgtt tataccatat ggtgtccgga taatcagtca tttaaacaat
     2701 gaggttcaaa gatatgaaaa ggggaaattt gatgaagaaa ataagcaatg aaatccaaat
     2761 tctggcagaa actttaactc ttcccaaagt cgttatagag caaatgattg tacaagcaaa
     2821 aaacatcctt gatgaggtgt ttgagcaata tagtcatgaa ctaatggatc ctaataaagc
     2881 aaaggcgact gcaaagaaaa tagacaaagt ctatgaagag gaaccttttg cagcattagc
     2941 tatttatcta tatgcagctt ctcaaagttg gaaaaaaatt tatcaaccat tgaagattcc
     3001 aagaactatc tatttggcaa caatgaatgc ttttactaga tttattcatg aacatttcca
     3061 agtaacagga agctatcgct ttgaccgtgg tttttggatt tggcattaca ctagtggctt
     3121 gatctttcgg attggtgaat tggagtacga aatgacatat tttccgaaag ggtacacgga
     3181 tctaagatta gaaggaaagc agtgcctttc tcttcatatt ccttccgatg cagatttatc
     3241 tcagaataag ataagagata gttacgaaag tgccattcgt ttttttgaac tttattttcc
     3301 tgattaccat taccaagtga tgtacacaga tacttggtta ctatcaccca atcttactaa
     3361 atagttgaaa aaagagtcaa aaatctgtct ttttgcagcc gattatcgat tattatcagt
     3421 tgatgaacag gacgatagtg gagtcccttg gatctttgga cgagtagatg cccaaataca
     3481 tgattatcca gaaagtacga gtttacagcg acaagcaaaa gagcaattgc ttgcaggcga
     3541 gcacattggc tctggcttag gtattcttac ttcataagtt tagtacttcg aaatagttta
     3601 aaagagcgtg agacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg
     3661 gcggaagcag aagcaactcc ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa
     3721 ttttcgtgaa tttcttctta tttcttggag ttaaacgctt ctgtcccagc ctctttttta
     3781 gtgttctatc gaacacacag tacgttcaat aggtaaacta gctataacaa tagatattaa
     3841 agttaacgga caagagggcc ttttttaggt agctaaaacg taataatgaa aatttatttc
     3901 cagagatagg agtcaatcag ctagtctgat cgactgtttt aacaagttga ctttcatttt
     3961 aacttttgat accatttaaa acacaaatcg taattgtttc gatttgtgtt ttttagcatg
     4021 actacaatca aagaagaaag tgggtcgtcc atatggaaaa aacagatatc tcaagtgcat
     4081 accgccgctt gaaaagccca aatatcaaaa cacgaaaacg tgcgctgaag atcatcaaag
     4141 atgtgaaacg gaatagtggg aaaaggtaag aagaaggaaa cttaattaaa aaaatagccg
     4201 aaaaacgttt ttcggctatt ttcaataatc ggtttttgtg taaggtttcc gaaagaactg
     4261 ctgttgattt tccattttta acatatgata aattggtaga atctttcttt tcaaattgat
     4321 accattccct aattccagtt atatagttaa ctacagaacc acaaagcacg tacgtttata
     4381 aaagtattat ctgtagttat ttttcaattc cctttcaacc tcttattttg accagtagta
     4441 ttgatcactt taccttttaa cacctttgtt cgtttttgaa acatttttag tcaagaatgg
     4501 aaacgtaact acataatcaa aggttttgcg aaatatttca tgaaatattt catgtagaag
     4561 cgagcaatac ggttgcaaat aaccattatc gtttaataag cagttacgaa agctcccaat
     4621 atctctaacg ttcagctcac tccatttctt ttcttcaaaa aaatcagtga ttcgtatctc
     4681 tttctatttg tcgaaaaagt taactttaaa aagtaacgcc gaaaaaatat gcaaaaaaat
     4741 aaaaaagcag ttactattgc tagaataaca tcaaggaata ataagttttg gttttcagat
     4801 aatagtcgat aagttgtgta ttggaatttt agatacagta ataaagtatt tttcatgaaa
     4861 ttttgtgaga atcactatta caagtatctt taataaaatt aatggttaag gaggaactta
     4921 aagtagaatg taaatgaata gttgtagtca gtcgattgtg atactagact caaagttgca
     4981 ggaataagtt tttcaatttg tgattggaag ataaaaaatg aaaaagaagg gctttttttt
     5041 atactttgtt gattgtagtg tttattttcc ctctgtttag ccaagtaaca ttttctatga
     5101 ctcaaccagt ttcaagtgag gaacatgata acctttttcg tgctacagaa gagtttaaga
     5161 aatatcagga aaatattgtt ccggagactc cattagctag tgagccaatt actgatattg
     5221 atggaaacca aataggatgg tatatacagt acgaagttat ggtggtaaat aatgactcaa
     5281 tagtaaaaaa tacagtaggc ttagagctaa caccgattga aaaggtgagt tcattgttaa
     5341 cgtatattta tactgatgaa agtgacgaga ctgagatcat tttaacggat tactcaaaaa
     5401 ttgctactga taaaaagtat atattgtgga tgtagacact agtgaaatac tttatgatat
     5461 agaaattgat gaaaatttac tagatgtagc acaagaaatc gatcatcaaa agcaggaagc
     5521 tattcgatat gctggtagaa aagggaaaag aaaatattta ttacgtgaat gtagcaaaag
     5581 ttagagaaga tgaaaatgag tggaaagaat tcaagagtcg ctactcaatt aactcgactc
     5641 cgacatttac agtttacaga gaaggatcga tagaaaaaac tgttttttgg actaaagaaa
     5701 gtggaatgtc tttagctgaa gtagaagagt ttttggatta tgttagtatg caacagtaag
     5761 ggagttctta ttatgaaaaa ttttgacaca tattatgtta ttgttttttc gatatctttg
     5821 ctgttaatat tactaacttt aatgcagtat aaagagtatc cagagtattt tattttaact
     5881 tttgtatatt tagtaagtag ctacacactt ctatataaat tcagaagttc ttctagagt
//
LOCUS       DADVXK010000130         5779 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.132, whole genome shotgun sequence.
ACCESSION   DADVXK010000130 DADVXK010000000
VERSION     DADVXK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.132"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..813
                     /locus_tag="KB909_002577"
     CDS             <1..813
                     /locus_tag="KB909_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6838540.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="KB909_002578"
     CDS             807..1229
                     /locus_tag="KB909_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838541.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="KB909_002579"
     CDS             2363..3331
                     /locus_tag="KB909_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6838542.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="KB909_002580"
     CDS             3341..3829
                     /locus_tag="KB909_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6838543.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="KB909_002581"
     CDS             4125..4406
                     /locus_tag="KB909_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838544.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="KB909_002582"
     CDS             4408..4824
                     /locus_tag="KB909_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838545.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="KB909_002583"
     CDS             5438..>5779
                     /locus_tag="KB909_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6838546.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2154 a          980 c          948 g         1697 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 ccataggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcggctgg atcggttggt
     5281 agaggggcta cttggcatag tgtacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DADVXK010000131         5696 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.133, whole genome shotgun sequence.
ACCESSION   DADVXK010000131 DADVXK010000000
VERSION     DADVXK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.133"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..434)
                     /locus_tag="KB909_002584"
     CDS             complement(<1..434)
                     /locus_tag="KB909_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBB6838547.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDA"
     gene            complement(447..671)
                     /locus_tag="KB909_002585"
     CDS             complement(447..671)
                     /locus_tag="KB909_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838548.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(775..2685)
                     /gene="ltrA"
                     /locus_tag="KB909_002586"
     CDS             complement(775..2685)
                     /gene="ltrA"
                     /locus_tag="KB909_002586"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6838549.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(3431..3568)
                     /locus_tag="KB909_002587"
     CDS             complement(3431..3568)
                     /locus_tag="KB909_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBB6838550.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(3565..4749)
                     /locus_tag="KB909_002588"
     CDS             complement(3565..4749)
                     /locus_tag="KB909_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6838551.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(5008..5298)
                     /locus_tag="KB909_002589"
     CDS             complement(5008..5298)
                     /locus_tag="KB909_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838552.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(5288..>5696)
                     /locus_tag="KB909_002590"
     CDS             complement(5288..>5696)
                     /locus_tag="KB909_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6838553.1"
                     /translation="RVYEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFP
                     NSTSRRGRLGKQSVHTLLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVN
                     SDSQLYKQAGNSVTVPVIFDIARRLKELDVHGL"
BASE COUNT         1524 a         1285 c          903 g         1984 t
ORIGIN      
        1 cacgcatcaa aatcaatata cgtcttcaag tgttctggta cttctccaaa atcaccagct
       61 tctacaatca agaaatatgc tacatcactc atatcatcgc aatctggata atagataata
      121 tcatccacat gctctaccat ctcctcaaaa gaattgaaga aagcatgttg aatctcagaa
      181 gcaacttcac caactggcgt tccttcaagt tcctccgcta agccacacaa ccgattaatt
      241 tcctcaattg gcgtatactc atcaatctca aagggaagtt cataatcatg aattgcatat
      301 tcctcgtatt cgtcatttaa cccaattcgt tctttcactt catcaaaatc gacaggtggg
      361 gtaaaccacg cccccaccaa ttcaccttcg ttatatttcc cgaggttcgc aatataaaca
      421 cgcatctgtt ccatcgtgct tcccccttac gcaccgacaa ttcggttaaa caaactgagt
      481 aagacatcct tcaccccaga agcattaaag accaatccga ccgcaatcaa agcaatcacc
      541 aaaaagccaa tcagtttgga aaactcccgc ttaaatccta aaaacaaacc aatgaccaca
      601 attgccagta agactaagga ttgggcattg gttaaaaacc attgatatat ggataggtaa
      661 gttcctgata ttataaatat ctcaaacttt tccccccatt cacacggagc gtgcgacttt
      721 caccgcactc cgcgttccat cgtgtttata ttgaaaagta tttatgtagt agacctatat
      781 caagtttaat tcttgattgc cagctaatac tctatattta tttagtctta tgagctggac
      841 tttatttagc ttcaatagag ctatatattt ttgtattgtt tcttctgttt tagcgtgtat
      901 tagacggtgt accgcctctt ttaccaaaat aagattttta taatcgtcat ttccaccagc
      961 tccagttggt acaatatgat gacaatgtat ttcattagct tgttgaaatt cttccagagt
     1021 tatagcacat tttccatgtt gagcagaaaa tagcgaaatt cgattgtctg cgtattctat
     1081 tgtgcgattt tccaaagata atttcattaa ctggtacatc agtaatttat caacacttag
     1141 attggtgtgg ataaattttc ttccctctag agtgtagcaa ttcgctaaat acacctttgc
     1201 cattggtttt ctgtgttgga tatatccaac agggaaaata ggttcgccct cgccagcaac
     1261 ataccgaagc attttagatt taccatatct tgttgcctcc tttgtcgtaa gttgtctgcc
     1321 tgtttttctc aatctgcccc ttttgtttgt acctaatctg ttagtgaaga tagccattac
     1381 agctctattc agtttcatac aatccagatt tacattcgtt gcaatctgat aataattttg
     1441 catacctaat accattgaat tataaagtct tgtttcttct aattccgttt tcccttttga
     1501 gggagaagca attttctttg cctgtgatac cagcttgtct ttttggtttt tgaattgttt
     1561 atcacttata tgtgatttaa caactaactt ctttcttctc ggtatcattt taatcttgaa
     1621 accaagaaag tcggagtatc tttttctaac atttacaatt cttgtttttt cttgtgatac
     1681 ttccaatttt aatcgttgtt caatccattg agtgattgct attttggctt tttcagcact
     1741 ttccttgtag cggcagaaaa ctctaaaatc atctgcataa cgaaccatat acatttcctt
     1801 taactttgtt ttcttcattt ctttgtaagc gttgctttta catgggctac cgcttttatt
     1861 gatatgaacc acatagtttt ttgtaacagg attttcctgc cattggcttt ctacccaatg
     1921 gtctaactca ttaagaacaa tgtttgctag tagtggggat attattcccc cttgcggagt
     1981 tcctttctct ggatatgtta ttgtaccgtt agtcattttg attggagctt ttaatatcct
     2041 ttttaaaatg aatatcaagt gcttgtcccg tattcccata gcccatatct gttttatcag
     2101 cttggaatgg ttcacgttgt caaagaaacc cttaatatca aattcaatca cataatgtag
     2161 ctggctgatt tgtaggcggt tataggttgc ttttattgca ttttcaactg acctattagg
     2221 tctaaaacca tagctgtttt cactaaattt agcttcgcag attggttcta atacttgttt
     2281 tatacattgt tgtataagcc tgtcccacat acaaggaata cctagaggtc tggttttacc
     2341 atttggtttt ggtatttctt ttcgcctcac tggcttaggt cgatacccat gtggactgcc
     2401 tgcaacaatg tatcttactt ttttgacaac tgtttctgct ggcaatttgc caatatcttt
     2461 aattattgta ccgtctgttc ctgctgtttt actgcctgca tttgctttga tatttcgata
     2521 tgccagtaat atattttctc tcgataggat aatatccata agatgagtga aaatatctcc
     2581 attcttactt ttggcatata aatcatcaaa ggtgttttgc atttcgtaat attcagcgtg
     2641 tcttaaatct tctacacaca atgtttcatt tttattttta ggcataaggc ttcactcctt
     2701 tacttgaaat tgagtgagct tttttatctt actcgtaatc cttattgaaa caacataata
     2761 cttttctaat atatacacga cttgagggca ttcctccatt ctcattacaa gaatttctta
     2821 ggttcgccct ctgcttttca gcattagttc aactgcttat tgttcttcgt cagtttattc
     2881 tcttgatgag aacccaatac ctttcctcgt tccgataatc ttatctatac atatatatcc
     2941 ttaggtcact agctataagc ctgctggctt gataccgcct gtaacgttat atggcatttc
     3001 ataacctata ttcttacttt gccacaccag ctacgatttc tcgtaccttt gcatttctac
     3061 aaagttcaaa tttagacccg tacattcgct gtttcgtcag ttccttatag aacattctaa
     3121 ccatagatat tttatagacc cccgacctgt tggatacgct acccacctct ggatagtttt
     3181 cgatagaaga tatatgttca tcaactatta cggtatcttt cagccgtctt taccgagctt
     3241 caaacattct gagtttcctc atacaatgct tgtcggaggc tcagggcagg cgtttcagag
     3301 cgttacttca tcattccacc tgtcagatta tcagttctcc taataaccaa actttttcgt
     3361 tcttttatta gtgccttagc ttttcactaa ggaacgagtc gcacataaat tttgtccgaa
     3421 attcatcttg tcactttcct ttcttttcca ttgctcgatc cgctgctgca cttgcattca
     3481 tcaagcacat cacagtaaca ccaagcatac tgccaccaaa taccaaaaaa atatctttta
     3541 caattcccat gacgattcct cttttcatat aatcaaattt tcaattgcca tactttgttg
     3601 ctccaaaatc tttttatgtc ggtctgataa gcgtgcattc tgtaccatat cctggatata
     3661 ggttgtccga ttcaatcgat ccaactcctt agccattttc cacgtagggg cgacttgtcg
     3721 gcctagccaa ttcaaggttc gttcaatggt atacggtttt ggctcggaag ttaattgaat
     3781 ctctttccga ttccgtccaa taaaacgccc ccattgttca ttcaagggcc agttggttcg
     3841 ccttttacct tctactttat ccgcaaatcg caagtaacga ttgataatgg aaaacgtggt
     3901 gctctcaatg ctacgacctt ttaacaaatc ttgaatcgca tgaaaagcac ggtcattttt
     3961 cagtcgaatc tcaaaacgat ttttcgtctc agtttggtct aatggaatcc ctaacttgat
     4021 atattgttca tagtcttttt catacaaaca gaaataaacc tcactcttga gactgccgat
     4081 atataaggta ttgcccatgc cgtccttttc atcagccttt aaaagttccc cggaacgata
     4141 acttttaaag gtacgaaaca aggagataca ttcttccttc tgacattttt tcgttagctc
     4201 aggtatatcc aatagcccca ctcgatcatt gattgccaag tccaagcgtt tcatcacgcc
     4261 accggccttt agacaatcct cgaaaaagtc gtaccagcta cgcttttgag cgagtaaaaa
     4321 agtttcaaat tgtcggcaac ctcgcccctt taattctaaa agcacacctt tatcttcttc
     4381 atgagacaac atcaccacaa tatcacccat gacatactgt tcttgatagg agtaaaaggc
     4441 ataatcttca tggagcatat actcaaattt caaatggaga atttcttgaa taatttttcg
     4501 tgcatccgtt gtgggaaagc gaatccttac atagtcaaac agtaacgtca aaggcaaatc
     4561 gggattaaag ctttccagtt ggtcaaaaat tttcctcatg gtttttatag atgcggttac
     4621 gccaccattt tctatctgat ttaagtacgg ccgactaagt ccacaagccg tagccaattt
     4681 attttgtgaa acgccgtatt cgttgcgtcg gtcttttaat agccgataat ctaaattccg
     4741 ttgtgccaag ttctcacctc caaattcaag gtgttaactt tttcaaatga gttaacacct
     4801 atacaaatta cttactatct ttgatacaac aagcattctt aatggttgct tacttatttt
     4861 ttgtgttttt gtacccccct gttagatacg ggggtgagac atcatggtcg gctaacgccg
     4921 tccatgaaca ggcacagcac cacggaggat ttctgcttcg cgaatcctcc gcggtcagcg
     4981 cctaacagtc agttgtgttg gtttaggtta ctcatctgta ataccattta cttccaactc
     5041 tgctttcatt tctaacaagt attgacgaat atctggttct tttgcttggt ccgcaatccg
     5101 ctcaaattct gcaattactt gatttatttc aattcgagca tccgtctcct cattcattaa
     5161 atatggatcg ccagcgactt tgacaccatt cttgcgaata tcaaatttta accgtcgcaa
     5221 ttgttcttct aattctgggt ctgactgaat ctttccaatc acccaataaa tttctccaat
     5281 caactcatca taaaccatgt acatccaact cttttaatct tctggcaata tcaaaaatga
     5341 ccggaactgt tacagagttt ccggcttgct tatacaactg actatctgaa ttgacttgag
     5401 aatctcgatc aaaagcccaa tcgggaaagc cctgaagtcg ccaacactct ctaggtgtta
     5461 gcttccgaat ttgatactga tccgtgacga tcgcttgttg gtctcctgtt agtaaggtat
     5521 gaacactctg ttttcccaga cgacctcggc gacttgtgga attaggaaaa gccagattca
     5581 cactgtcttc tggcttcacc tcttgatatt ctgtttcatt ttttcgaatc atgatttttg
     5641 taccaccttg tttcgttgac aaggtggggg cggttccagt aacttcataa actcga
//
LOCUS       DADVXK010000132         5679 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.134, whole genome shotgun sequence.
ACCESSION   DADVXK010000132 DADVXK010000000
VERSION     DADVXK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.134"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(240..606)
                     /gene="ssrA"
                     /locus_tag="KB909_002591"
     tmRNA           complement(240..606)
                     /gene="ssrA"
                     /locus_tag="KB909_002591"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(777..1550)
                     /locus_tag="KB909_002592"
     CDS             complement(777..1550)
                     /locus_tag="KB909_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6838554.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1694..2044
                     /locus_tag="KB909_002593"
     CDS             1694..2044
                     /locus_tag="KB909_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6838555.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2025..2741
                     /locus_tag="KB909_002594"
     CDS             2025..2741
                     /locus_tag="KB909_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838556.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2741..4189
                     /locus_tag="KB909_002595"
     CDS             2741..4189
                     /locus_tag="KB909_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6838557.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4260..4769)
                     /locus_tag="KB909_002596"
     CDS             complement(4260..4769)
                     /locus_tag="KB909_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838558.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4759..5484)
                     /locus_tag="KB909_002597"
     CDS             complement(4759..5484)
                     /locus_tag="KB909_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838559.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1936 a          984 c         1120 g         1639 t
ORIGIN      
        1 gtttttcctt ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt
       61 ttgtaaagta ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt
      121 tttgaatgct attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa
      181 atgctcaaac ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac
      241 aatggagacg gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt
      301 catagtcaac tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc
      361 gctagtctga tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa
      421 gttaggaccc ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta
      481 ggcagctaaa gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt
      541 tacgtagacg taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac
      601 gtccccgtta gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat
      661 tgggataaat tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt
      721 tcttaagaaa aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa
      781 atcagatcaa aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata
      841 aaggtagaaa gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa
      901 gcttccaaca aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc
      961 agctgaagtt ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact
     1021 gtatcgatcg agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag
     1081 tattcgtcac ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct
     1141 aaaggatcaa tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg
     1201 ctatgaccgg tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac
     1261 tgtacatgat catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct
     1321 tcgccgtcta ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct
     1381 tccatgatag agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg
     1441 ttttctttta atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct
     1501 agtaatgttc catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact
     1561 ccttttttat tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg
     1621 aagaattcct gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt
     1681 taggagggaa agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct
     1741 ttttcggatt ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc
     1801 cgcaaaaaca gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct
     1861 tatgggctta ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta
     1921 ttttctgatt gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga
     1981 aaagaaatta cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga
     2041 ttgaagataa tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg
     2101 aagcaacttt caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac
     2161 attgggatat gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa
     2221 gagagatccg caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg
     2281 aaagcgatca ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca
     2341 gtcctctgac gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag
     2401 caagagaaga agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga
     2461 tgaatacgaa aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta
     2521 aagagttcga tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc
     2581 agttgcttga attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc
     2641 atatcaagaa attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt
     2701 ggggagtcgg ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca
     2761 actcttagct ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac
     2821 acaactgaca aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga
     2881 atcagttgaa aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca
     2941 ggcgtttcaa aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt
     3001 tatatttatc gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt
     3061 taccttaaca gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc
     3121 gaataaaaat attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt
     3181 gaatcatgaa ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag
     3241 cgttcgtcca attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt
     3301 tattgccagc tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc
     3361 gacgaaagaa gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga
     3421 atttgatgag ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc
     3481 agaaattgaa gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat
     3541 gagaacacct cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc
     3601 tgaaaatcag cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg
     3661 tttggtgaat gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat
     3721 taaaaaattc aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc
     3781 agaagcagca ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga
     3841 ttatgaccga tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga
     3901 aaacggccaa atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga
     3961 agatacggga attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa
     4021 agtagatcct tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt
     4081 gcagcaactt gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg
     4141 aacaaaattc gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg
     4201 tataaaagat catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt
     4261 tagcccgcgg gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta
     4321 aagagtaaga taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct
     4381 tggatctcca atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg
     4441 gaaagcaagg catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc
     4501 gcacaattaa gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt
     4561 ttgatttctt tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac
     4621 atcggccaat ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt
     4681 ttcaagtgct ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt
     4741 tcagcatgaa tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg
     4801 gataaaaaaa gtgaaaggga atagactaag aatgagacag catccactga gcccaataag
     4861 agtttgggca aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt
     4921 aaaaaaagtc tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg
     4981 gatatctggc agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc
     5041 ataaactgac tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg
     5101 aaagaacagc tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg
     5161 ccaattgatc aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag
     5221 gaaggcaaat agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc
     5281 taaagccgga agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac
     5341 ttgattggct aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc
     5401 agaaaagctt gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc
     5461 agtagcatag cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata
     5521 tgaataaagt atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta
     5581 aaaagcaaga ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa
     5641 cactgtttat tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DADVXK010000133         5603 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.136, whole genome shotgun sequence.
ACCESSION   DADVXK010000133 DADVXK010000000
VERSION     DADVXK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.136"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(29..1261)
                     /locus_tag="KB909_002598"
     CDS             complement(29..1261)
                     /locus_tag="KB909_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBB6838560.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="KB909_002599"
     CDS             1516..2085
                     /locus_tag="KB909_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6838561.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="KB909_002600"
     CDS             complement(2263..2703)
                     /locus_tag="KB909_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBB6838562.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="KB909_002601"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="KB909_002601"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBB6838563.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="KB909_002602"
     CDS             3657..4580
                     /locus_tag="KB909_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBB6838564.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="KB909_002603"
     CDS             complement(4805..5044)
                     /locus_tag="KB909_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838565.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="KB909_002604"
     CDS             complement(5049..5468)
                     /locus_tag="KB909_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6838566.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
BASE COUNT         1720 a         1057 c         1043 g         1783 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat att
//
LOCUS       DADVXK010000134         5358 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.137, whole genome shotgun sequence.
ACCESSION   DADVXK010000134 DADVXK010000000
VERSION     DADVXK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.137"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..273)
                     /locus_tag="KB909_002605"
     CDS             complement(<1..273)
                     /locus_tag="KB909_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBB6838567.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(245..1198)
                     /locus_tag="KB909_002606"
     CDS             complement(245..1198)
                     /locus_tag="KB909_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6838568.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1810..3303
                     /locus_tag="KB909_002607"
     CDS             1810..3303
                     /locus_tag="KB909_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6838569.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3438..3734
                     /locus_tag="KB909_002608"
     CDS             3438..3734
                     /locus_tag="KB909_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6838570.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3835..4686
                     /locus_tag="KB909_002609"
     CDS             3835..4686
                     /locus_tag="KB909_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838571.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4707..4990
                     /locus_tag="KB909_002610"
                     /pseudo
     CDS             4707..4990
                     /locus_tag="KB909_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1835 a          829 c         1016 g         1678 t
ORIGIN      
        1 atcttttgat cgtctattat atataatccg ttcctcgtcg tttaaagtat caacataggc
       61 gtccattgca agtttgacta tttcatacat aggaatatct tttgcataac taagatcccg
      121 aatggttttt agtacgggag gatctacttg aactggtttt ctttctttcg cagtgtactt
      181 tcgttcccct aactcgacat taatatcatc tttaattgaa atatcttcag caccaatttt
      241 cttcttatct ttgttcgttg gtaataatgc catttagttt aatctccttt ccaagaggta
      301 ggatatgatt ggccattgag tcagcatatt taggtgtata atcaaatcct tcaatatcac
      361 catgttgttc atagtattca attctttctt ctaattctgt aaagatgtct gcaaaaatag
      421 cccaccatct tcgatctaca taatcattta attggatacc attctcacca tacatttcta
      481 accgatccga gcctttaaca atgcttttaa aaatgtttga ttcaccatac ttatcaattg
      541 ttttttgata gtttgcgtgt tgagaggaac gtcgcactga gaaaagaaca ggcaaaattc
      601 caatgatttg aagatgagac tcttcaaaat tcgtgacaat cggaactaaa actttattaa
      661 taaaatcttc tgttccttcc attgcgtacc gttttaattc ttgcattgca ataatataat
      721 ctgcagcagt taagaatgca cgaaccacat tatctgttga tggtgggcag tcgataaaga
      781 tataatcgaa attttttctc aattcttcta aaggtttaat gaaggccaat gatctcttac
      841 gacgatcagg atatttttcg gacaagtatt cattaagttc ttcagatcca ggagagccag
      901 ccataatata taaatgtgga cttacttgag taatacctga aacccagtcc ccttttttga
      961 ttgctgcaga catggatcga tcaaagctag taatttgata cgttgatcca atgttggaag
     1021 tagtatttct ttgttggtca taatcaatta gcaacacgtc tttttcaaaa agttgactag
     1081 aaacaatcgc taataaatca ttgtctgtag tcttaccaat gccgcctttt ctacctgtaa
     1141 gcattacaac ttttcctagt ttatctgatg ttttaaatgc agtccgtaag ttttccatag
     1201 ttccctccaa tttcctatac taaatatatt tagtatactt catatactta atatattcga
     1261 tatatctaat atactccaaa ttgataagaa ttcagacttt ataaggaata tagtggatat
     1321 actaaatata tttgctatat tcagtatatc agatatattc aaaatgtcaa aatatatttg
     1381 tgcgttttgc gttgacaatt tagagtgaaa agaggtaaac ttaattctat agaaaccaca
     1441 gataattcac tatttacaaa gtagcaaaag cagtggtact ctttaaacag aaaaattaca
     1501 taaaaaaaag agacggaaat aattgatttt agcagaatca attatttctg aatcacatgg
     1561 ttaggacatg tgttcacgct cgtctcaaga atatgtaagt agctaccaac tacttatatt
     1621 aaaagttgat cggatacctt ttccgattgc ctttattcta ccaaaaaaag gcgagcaact
     1681 caacagaaga acgtttattt agtgtactta aattaaatat tcttaaacac tgaagagaga
     1741 acacatacta tggctgagat taaagctaaa ctgtgttctc tttttgtttg agaaaggacg
     1801 ttacaatcga tgttgagcga aatttattca gctattctta aaaacggctt acgtacatac
     1861 aaatatcgaa acagcaccat gaaacctgca ggtcatattg attccagtag gagtggtgct
     1921 atctttgcgt accgtagcaa gcaattaatg aatgttgggc gtggtatggt cattacttcg
     1981 gaagaagcta ttttagagaa cgaaaagaaa ctaacgcatt ggacacctaa tacctatcgc
     2041 tttggtactt atgcggatga ttatcgaaca gtggttaaag gtcattctga gaaaaactta
     2101 agtcaaatca acacatttgt agttgatatc gattcaaaag agaaccatca aggcgaaatt
     2161 attttagcct gtttagatca agtgggctac atgccaacgc taattttaga atcagatcat
     2221 ggttatcaag tttattttgt actaaagaca ccaggctatg tcacaaagaa aagcaatttc
     2281 aaggtgatcg atgtagcaaa aaaaatttca aaaacaattc gtctacagtt ggctgaaaaa
     2341 ttgtccggag tggatctagg atgtaaccac ttcggaattg ctcgattccc acaagaaaat
     2401 aatattgttt ttaaagaaat gaactatcag tattcttttg ctgactggat tcaatggtcg
     2461 atgaagcttg aatcagatca aaaaacaaaa gaagatcgag aacgaaaact aattgtcttt
     2521 cctgagaaaa aagaaattcg tcaagtagat gaaccgtggt tcgatatgtt acttcataaa
     2581 gcaaacatcg tcggcggaga aggacgtctt ggtcgaaata atgtgatttt cacgctttct
     2641 ttagcttatt actcttcagg ttatgcattg gatacttgcg aatacaatat gttcacattc
     2701 aacgaacggt tacaggaacc gctatctgaa gcagaattag taaagattgt acgtagtgct
     2761 tattctggta attatcaagc agcaagcaga gaattcatta ttgaattgtg ccagcaatgg
     2821 gtttcaccaa ccttaaaaaa taatgatctg ttcattcaac gacgtggctg gtggaaattt
     2881 aaaaagccac gagatcaaag aaaatatagt cataaaaatg aatggaaaga agatctattg
     2941 gcttatctaa gcgaaaaaag tcttgctagt gagccttatt tgaacctgtc aaaaaaagaa
     3001 ttggcttcac aactaacgat gcccaagcga acacttgata agatcttaaa tgagttacga
     3061 gaggagaata aagtcttcta caaggtaaca cgaggaagaa atggcggaat gatcattgct
     3121 tcagtcaaaa cgttgttcgc gagggttatt caactaagta aagaaaagag actagattat
     3181 tcaacaagga tcacagaggt atttggactc aacgagagct tagtagaaga gacatttaga
     3241 caattatcaa cccccttgaa ccctcttaaa gaagtgaatc tttttgaagt agatacaggt
     3301 tgaaaaataa aaggtgcaaa ttgccttata caatatatct atgatacttc tgtaggtgtt
     3361 gctccctttg cctagctacg tgtaggtggt atacttataa ctgcgtatgc agtcttatgt
     3421 atcatggagg aagttgtatg tcgttaaaaa attatgtcta ttcacatcct gttaatgtgt
     3481 ttatcattgg tcgtttggga ttatctgtgg aagtgttctg tgagctttat ggttttaagc
     3541 aggggacttt gtcttcttgg gttaccaggg aaaaaacagt tgcttctttg ccgattgagt
     3601 ttcttcatgg gttgtcctta gcttctgggg agactatgga tcaggtatat gattgtttgt
     3661 gtgtgttaga gcaggagtat attgagtata aaatagctaa cgagttaaga aaaaggaaga
     3721 agtatatcca gtagtagttt ttatttactt aaaaaattgg ttcattgagc aacctatcgc
     3781 tgctaaagta gcaaaggaaa acgttaaagg aaagaattta gggaagaaat cgaaatgaaa
     3841 tcggacgact ggattgaaca cacctggctt cctctgaaaa gaaatagcaa acgaaagaaa
     3901 ttttgggtat tgcaattatg gccattagga aaactttgta gttacggggc acgacttatt
     3961 cttgatttaa ccgtttactc gattggagta tttggaacgg cttattactt gataaatgat
     4021 cccaatagga ttgcagcatc agacattttt acagtgctaa tgacgttgat ttttgtcatg
     4081 ctattgtcta tttttactca attagtcatg caatttacca ggcaaaaatt aacagcagga
     4141 aaacttttca aaagcctatt cgatttaatt gttgtaaatg caattctagc gactttaata
     4201 aaacaaattg aacaatctgg aagaacaaca aaaggagtga aggatttttt attgacgttt
     4261 attcactttg taaatggaca catgtatttg tttgaagtgg gtattattct cttttttgtc
     4321 gggtatgtat ccacgaaact tattaaacgt tcaattgaaa aagaaattga aattgacctg
     4381 attccgacac ttcttggtta tgagtacaat gttgattttg gaagatatga cgaattgatc
     4441 aatacggata tcgttcacac gagtatccat gaatctactg ttaagggcat cagatctatt
     4501 ttaaaaaatg gccaggaaat gaaagcaata gatcgaagaa aagagatcta caatttttat
     4561 gaagtcgaag caagcctacg atatggcatc ggaaaattgt ggttagatgg aagtaatatt
     4621 cgtcaaaaca aaccatacat tttttggaac agtagtgatt tagaacttcc aatgaaagat
     4681 aaataattat ggagaatcgt ttgaaaatga ttcctctata caggattgtg cttatagttg
     4741 gcatggagtt aaaaacctta aagaaggagc agttattcaa agtgaaagaa cgtcataatc
     4801 agttactatg tagtaaaacg ggtacgatga acattgaata ccgaacagaa tatttagaat
     4861 taacgaatca aactgatttt ttgttgattc gaaagcaaca agagcaagaa aaaaattaat
     4921 ggctacttat agccaattga ttgatgaatg ggaacaattc aaggaatcta aaattccaga
     4981 acgtctctaa aagcctttat ttgtaaagag cataaggaaa cgtgggaaca ctttttaaaa
     5041 aaagtgttcc aataggctgt gcctattacg tttctcaaaa ataaatgtgg gaacaaaata
     5101 tttaaaaata ggatagtgaa aggatagtga aggatagtaa aaggagggta gtaggatagc
     5161 aaaaaggata ggctcctttt cgctatcctt tttaaattgg aggaattaat atggaagtaa
     5221 gaataagaaa tgtggatgag aaaatcgtaa gagaaattga tcgaagatgt gacgaacggt
     5281 tctgttgcaa agttttaaat ctactatcaa ataaggtaga ataatagaaa aagatagcag
     5341 gaggaatgac gatgaatc
//
LOCUS       DADVXK010000135         5226 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.138, whole genome shotgun sequence.
ACCESSION   DADVXK010000135 DADVXK010000000
VERSION     DADVXK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.138"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            151..2085
                     /locus_tag="KB909_002611"
     CDS             151..2085
                     /locus_tag="KB909_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6838572.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            2542..2958
                     /locus_tag="KB909_002612"
     CDS             2542..2958
                     /locus_tag="KB909_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6838573.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            2972..3538
                     /locus_tag="KB909_002613"
     CDS             2972..3538
                     /locus_tag="KB909_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBB6838574.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            3561..4547
                     /locus_tag="KB909_002614"
     CDS             3561..4547
                     /locus_tag="KB909_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6838575.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(4702..>5226)
                     /gene="scm"
                     /locus_tag="KB909_002615"
     CDS             complement(4702..>5226)
                     /gene="scm"
                     /locus_tag="KB909_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6838576.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         1592 a          956 c         1149 g         1529 t
ORIGIN      
        1 gctttatttt aaaatttgaa aaaaatccaa aaggagttag acaaaagaac agaacatcta
       61 tataatatat ggagattgtg taataagtat caaactaaaa gaattatcat atattcatta
      121 tatagatagt ctataaggag cggatgatca atggcaaagc aaaatattgt cgttgtagga
      181 gcaggatatg ccggtgtttc agctacaaaa tacttggcaa agaaactgaa aaaagaagat
      241 gtagcaatta ctctgatcga tcgtcattcg taccatacta tgatgaccga gttgcatgaa
      301 gtagctggcg gacgtgtaga accagaagca atccaatacg atctgcagca tttgtttgct
      361 cgtcaaaaga atgtacaact tgtcacagac actgtaatcg gtatcgataa agaacgaaaa
      421 atcgtcaaga ccaaattagg ttcctatcct tttgatcagc tgatccttgg aatgggcgga
      481 gagccgaatg actttggtac acctggtgtc aaagcacacg gattcaccct ttggtcattt
      541 gaagattctg taaggattcg ggaacatatt gagaagacag tagcaaaagc tgcattggaa
      601 ccagatgatg aactgcgtaa agccatgctg actttcgttg tctgtggttc tggatttacc
      661 ggtattgaaa tgattgggga actgatcgac tggaaaaatc gcctagccaa agattataaa
      721 ttagatccaa acgaaatcac actgatggtc gtagaggcaa tgccgacgat cttgaatatg
      781 ttggatcgaa atgatgctgc aaaagctgaa cgctatttgc gtaagcacaa cgtggaatta
      841 ttattgaatg caccaatcgt agaagtggct gctgatcata tcaaattgaa agacggacgc
      901 aacattccga ctcacacact gatttggaca gctggtgtca aaggaacttc tgacgctgct
      961 gactttggat tagaatcagc acgcggacag cggttgatcg ccaatgaata tatgcaggca
     1021 aaaggctacg aagataaaaa catctatatc attggtgatt tagtctttta tgaagaattc
     1081 ccaggaacac cgacaccgca gatcgttcaa gctgctgaac aaacaggaca cacagccgca
     1141 gcgaatatcg tggcttcgat caaaggcgga gaaaagcata aatttaaagg aaactatcaa
     1201 ggatttatgg tttctattgg tgccaaatgg ggggtagcta acctatttga taagatccat
     1261 ttaagcggat ttttagctat cgtaatgaaa catatcgtga atttgaaata cttctttgat
     1321 attcgttctg gttattatat gttccaatat ttaatgcatg agtttttcca tatcaaagat
     1381 gatcgcaacg tgactcgagg acattcttct cgttacggca atgtcttatg gagtgtgcca
     1441 cttcgtattt tctatggttt agtttggttc gttgaagctt ccaaaaaaat cattgggaat
     1501 ggtgaagtgt tcaaaccaag tacttggttt ggtgaaggat catggttcac tggaaacagt
     1561 gtgttccctt ggacatggga atacaatgta acagatgttg ccagtggtgc ttctgctgct
     1621 ggtgatgcaa ccacagctgc cagcggagca ggggcaagtg ccggagaagc agcgactcaa
     1681 gctgcacatt ttggtttgag ttatgcatac ggtgaagaac caatggctgt gattgagaag
     1741 tcaccagact ggttcacaaa gatcatgcaa gtgatcatgc caaacaatga tgtagcaatg
     1801 ttcttccaaa aattcatggt attctttgaa attgccttgg cattagcatt gattgctgga
     1861 ttattcacat ggctatgcag tgcgacaacg attgtattgg tgatcacgtt ctgcttatca
     1921 ggcatgtttt actgggtaaa catttggttc atttttgttg ctttcgcatt gatgaacggt
     1981 tccggacgtg cgattgggtt ggatcgctgg gtaattccat ggctacaacg tacactaggt
     2041 aattggtggt acggtagacc aagttcccag tacggcaaga aataaataga taaagaacgt
     2101 tatttgaatg caagatttca atagaaaggg gctgagacaa accgtcacag cctccttttt
     2161 atgtaaaatt aaaggaataa gatgcccgag ataagcctcc atgagcaaga cacaggtgtc
     2221 acaacctctg ttacaacctc ttgttataaa cggtgttcca gaagtagctt cttcgaaaaa
     2281 taagccgaaa tttcacaaaa acttgaaaag taattttcgt aaattccttc ttatttcttg
     2341 aagttgccca cttctgtcac aacctcttgt tataaacggt gttccacctg ctgcttctcg
     2401 gtaataagcc caaagaatta gaaaacatgg aaagctgttt tctattcttc gttcttatta
     2461 ctcaaagcaa gacacaggtg tcacaacctc ttgtttttat gctaaaattg ggtgagttaa
     2521 tctggaaaaa ggagaacaaa aatgagcctt aaagaatttg ctgaaaaaag tctgctcaaa
     2581 ccttgggatg tttttattat tttgcttttg actgttcttt cttttttacc agtcatgatt
     2641 tttggtcttc agcaaaacac cgcaacagca gaaaaagaag cggtactgcg tgtggatggc
     2701 acagaaatca aaacattccc tttgatggct ggagaagaga gcaacacata tacttacaaa
     2761 gatgaacacg gagattataa cttgatcgag atagatggcg atcgagtacg gataaaagaa
     2821 gcagattgcg atgaccagat ctgcgtacgt cgaggctggg caacgaaaaa tggcgaaacc
     2881 atcgtctgtt tgccacataa attagtgatc gaagtccgtt caacagatgg aggtgacgaa
     2941 gacagtctga tttattagac cttcacacac catgagtaaa ttacaaaaaa tgatttatat
     3001 ttcgctactt gttgcacaag gagtgatcat tggtttattg gaaaatatga tcccttatcc
     3061 tttttctttt gcgcctggtg caaaactagg cttagccaat ctaatcacga tcgttgccat
     3121 ttttaccatg aaaaaacgag acagcttctt actactttgg ctacgactat tcctgactac
     3181 tttgctaggc ggaacgattt ccacattcct ttatagtatg agtggtgctt tgcttagtta
     3241 ttttggaatg ttattggtca agcaattagg accaaaacgt gtcagtatca tcggaattag
     3301 tgcggccggc ggtttcatgc ataatgtcgg acagcttttg atggcttctt tcattgcaca
     3361 atcatggaca gtcatgttgt acttgccagt cctttcagtt ttagggattt tatcagggat
     3421 tgcaatcggg atcgcagcga attatctttt acgacatgtg cagacacttc aacgattcca
     3481 aaaagattat gagcagggaa ccaaacaaaa atggagccca atgtttacca aaaaataatc
     3541 gtcacacaag gagttttttt atgaagctac atccaatgtg ggaaaactat cctgctttaa
     3601 gtaaagaatt gacagaaaca ctaaaacgga tggaagaaac tgtccgcctg aaaaacaaac
     3661 ctgtcgaaca agcaatcaaa gaaacgatcc atgccggcgg aaagctgttg cgtcctgcct
     3721 atcagctatt gttctcacaa tttggaccag agcaagatcg agacaaagcc atcgctttgg
     3781 cagcttctat cgaaatgctc catacggcca cactgatcca tgatgatatc gttgatgaag
     3841 cggatctgcg acgtggtcag cctaatatcc gtagtcagtt tggtaatgtc gtttctgtct
     3901 atgcaggaga ctatttattt gtctgctgtt ttaaactatt gtctgattac tccacttcct
     3961 tgaaaagtct ccaattgaat tctcgcagta tggaaaaagt attgaatggc gaattagggc
     4021 agatggatga tcgctataat tatgaacttt ctgtaaaaga atatttggaa aatatttcag
     4081 gtaagacagc tgaactgttc caattaagtt gttctgttgg cgcttttgaa agtggaacaa
     4141 gcgagcgctt cgcaaaaaaa gcaggagata tcggactttc tatcgggatg gcctttcaga
     4201 ttatcgatga tattttagat tatacaaaag agagccagga aatcggcaaa cctgtactag
     4261 aagacatgcg tcaaggggtc tattctttac cgttgatcta ctctttgcaa aaaaacaaac
     4321 caaagctact accttattta gagaagaaag cggcaatgac agaagaagat gtcgacgccg
     4381 tacgcaaaat cgttgaacat acaggaggcg tggaagaagc taggaagtta gcggcctctt
     4441 acacagaaaa ggctttgaag gaaataaaga aattacctgc cacctctctt cgaacaaaag
     4501 agaatctctt ttcccttacc caactgattt tggatcgcaa agactgaata gggaaaggtt
     4561 cgatacgtaa ataaatttct cagaaggaaa tctacgtgtt ttttgacaaa ttgaattgta
     4621 gttcttgtat ttatgataaa aagcaaaaat aaagagcaac gtccgttagc gacgttgctc
     4681 ttttttatct tgaatatttt tttacctttt cgatttctta taactcataa aagtgattct
     4741 taaaccgatt acaagtaata taacgcctgc gagtgttatc caattattcg attgacttcc
     4801 agttttagga agtgctcttt ttgatttgtt tccattgtca ttgcttgttt tattagttaa
     4861 gttaaagttc gtcctgttat ccgaacttgt ttttgagaag gagacacttg catgacgtgt
     4921 atcgcttgtg gtagacgacg tgtctgtact atcgcttgaa gttgatgaat ctgagctatc
     4981 acttgtggta gaggatgtat ctgtactgtc acttgaagct gacgtgtccg tgctatcact
     5041 tgtagtggta gatgaatctg agctatcact tgtggtagag gtagtatctg tactgtcact
     5101 tgaagctgac gtgtccgtgc tatcacttgt tgtggtagat gtatccgtac tgtcgcttga
     5161 agctgacgtg tccgtgctat cacttgtggt agaggtagta tctgtactgt cacttgaagc
     5221 tgatgt
//
LOCUS       DADVXK010000136         5174 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.139, whole genome shotgun sequence.
ACCESSION   DADVXK010000136 DADVXK010000000
VERSION     DADVXK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.139"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            32..388
                     /locus_tag="KB909_002616"
     CDS             32..388
                     /locus_tag="KB909_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HBB6838577.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            404..754
                     /locus_tag="KB909_002617"
     CDS             404..754
                     /locus_tag="KB909_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HBB6838578.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            783..1562
                     /locus_tag="KB909_002618"
     CDS             783..1562
                     /locus_tag="KB909_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HBB6838579.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1573..2235
                     /locus_tag="KB909_002619"
     CDS             1573..2235
                     /locus_tag="KB909_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HBB6838580.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            2254..3360
                     /locus_tag="KB909_002620"
     CDS             2254..3360
                     /locus_tag="KB909_002620"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBB6838581.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3350..4441
                     /locus_tag="KB909_002621"
     CDS             3350..4441
                     /locus_tag="KB909_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBB6838582.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4454..>5174
                     /locus_tag="KB909_002622"
     CDS             4454..>5174
                     /locus_tag="KB909_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBB6838583.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSM"
BASE COUNT         1646 a          856 c         1245 g         1427 t
ORIGIN      
        1 acaaatgata ttttacgagg aggaaacaat catgattaaa gtagttattg cagaccgtat
       61 gggtaaagga caaaatgtgg ccaaaggggt agaagcagct ggtggaaaag cagttgtcgt
      121 accaggaatg ggggcagata tgcgtttggg cgatgtgatg caacaagagc atgcagatat
      181 gggtatctct ttttgtggta gtggtggtgc aggtgcatta acagcagcaa caaaatatgg
      241 ctatccagaa cgacatggta tgcgttcgat tgaagaaggg atcacagcta tcaaggatgg
      301 caaaactgtt ctaggtttcg gctttatgga tcaagaggaa ttagggaaac gtctgacaga
      361 agaatttatc aaaaagcatg gaaaatagaa agagggacat gaaatgagcg ttcaaaagac
      421 aattcagcaa aaagttatcg tctccggtaa aggggaaaca aagcaacatg cttttgcatc
      481 agcgttagca gaaattcaaa acaaaataat ggaacaatca aacgtattat tgcgaatcga
      541 accagtcaat gtggatattt taaaggcggt cgaaaacaaa tacacagaac gctttctatt
      601 tttcttcttc ccacggcaac gtattagcta tgaagtcgaa ctctctgtta ctgtggctgt
      661 aacagaaata aaattggcag acatatcgtt cagccagcaa atgactgaag atccaaatgg
      721 gattgccatt ccatttgtaa ctaaaaaaat ctaattttga atcataaggg ggaaagaata
      781 acgtggattt cgtaatcatt ctagtcaaat cggtcattat cgggggatta cttggttttg
      841 cagcatctgt cggggcagct cgaatgtttc atgcacctaa tacacaaggt ttaggagctt
      901 ttagaacatt aggcgaaatg aatgcctgca tgggtgatcc agcttctcat ttttcatttg
      961 gtttaggctt tttctttaat gcatgggctt cttcagttgg tgctggtgca ttcacacaag
     1021 atgtgacgca tcgaatcatt cccaattggg cagcggcagc acttctagca aaaaacaaag
     1081 atgtcaccca gaccatgcat gatccgaaaa aaatggggat cattggagcg gttatcgggg
     1141 cagtggtggt agccttctta aacacaacag ctgcagcaat tccagaggcg ttacaagtga
     1201 cggcggtttc cgttttggta ccagcagcga cgattctgat caatacagta atgccagtta
     1261 ttttttggtt ggcagcttta gacgcaggga aacgaactgg tttttggggc actctttttg
     1321 gtggtatcgc gcaattgatt atgggaaatg cggtacctgg tgttgttcta ggaatcttga
     1381 ttggtaaagg cgtcgatgag agcggttgga atcgcgtcac gaagagcatg atgatcgcta
     1441 ttgttttatt atttattttc agtggatttt tccgtggatt tgatatggaa atgatcaaga
     1501 gcttccagct tcaagtgcct aattggcttg ataacttgca caacatcttt agtgtgaaat
     1561 aggaggagaa tcatggagac aacagaagaa caagcaaaag tattagaagc aaagcggcaa
     1621 aagagctttt ggtttgcaga ctggtctttt ccgctaatcg taggaattat gtccgctgct
     1681 gtatttgcag gaacacacat gtatgtgatg tatggtgtgg gtgcattcaa tgaagtttcg
     1741 atcgtggcga tgttaaaagc cgggctggat ggcggatcct atggcgcagc ggcagcgttt
     1801 ggtgctagtt tcttatttgc cagaatttta gaaggctctt tagttgggat cttggactta
     1861 ggcggttcga tcctaactgg gatcggaatt ggggtaccag caattctctt aagtatgaaa
     1921 atagcggcac caatcgataa ttttgcactc tctttattga ctggtttggt tctaggtttg
     1981 attgttggtg gcatcattgt cttgattcgt aaatttacga tcaatcaatc aaattccact
     2041 tttggtgctg acgtcatgat gggggcagga aattcatctg gacgtttttt gggtccatta
     2101 attatattaa gcgcgtgtgc agcatctatt ccaatcggca ttggcgctac attaggagca
     2161 ctaggattct atgcttggaa aaaaccaatt gctggaggtg ctattttagg agcaatcttc
     2221 ccggcagtaa attaatagaa agagggtcat taaatgtttg atactttgat taaaaatgga
     2281 aggttagttg atggatctaa aatagaggtc gctatagaaa aaggcatgat taaagcagtt
     2341 gcagcagaaa taaatcagcc ggcgcaagaa gtagttgact tggagggaaa gtattattta
     2401 tccgctgggt ggatcgatga tcatgtccac tgctatgaaa agatgaatct ttattatgac
     2461 tatcctgatc agataggggt cgaaaaaggt gtgacgacgg tcattgatgc tggaactacg
     2521 ggagcagaaa acatccgtga attttatcaa ttgacgaaat cggtcaagac aaatgtgtat
     2581 gcgctaatga atatctctaa atggggcatt gtcaaacaag atgaacttgc tgatctaaca
     2641 aagattcaag aagatctagt aagtactgcg ttagcagaac tgccggaatt tattgtcggg
     2701 attaaagcga gaatgagtaa gacagttgtt ggtgaaaatg gcattaagcc attagaatta
     2761 gctaaaaaaa tccagacaga aaacaatgat ctgccattga tggttcatat cggttctgca
     2821 cctcctgagt tagaagaagt attgtcaaga atggaaagag gcgatgtatt gacccattgt
     2881 tttaatggaa aaccaaacgg tattttagat ccaaagacag atcaaattaa aaactttgtc
     2941 tgggatgctt acaataatgg tgtcgtcttt gatattggac atgggacgga tagctttaat
     3001 ttccatgtgg cagaaaccgc actaaaagca ggaatgaaag ctacctctat tagtacggat
     3061 atctacatcc gcaatcgtac aaatggccca gtttttgatc tagcaactac tttagaaaaa
     3121 ttgagggtag tcggctattc ttgggaagaa atcattgaaa aagttacagc agttcctgca
     3181 cggaattttc atttgaagaa taagggccag ttagctgtca attatgatgc agatttgacg
     3241 atatttgaga ttgttgaaaa tgaaaaggaa ttgaaagatt ccaacggatt tacacgtata
     3301 gctaaagaac aaattttacc gattaaaaca attattggag gcgtcatata tgacaattag
     3361 ctatggaaag tttgatttaa aagaagtcat taatgcatcg ggaaaaatga cgatcctagg
     3421 ggtttctaag gtatctgaaa gtgtcctagc agcacaacga tttggaggcg agcatttttt
     3481 tgagatgagt gatcttgcca tcaaaaccgg cgcttatctt tctcaattac tgaaagtgga
     3541 agatgcgcaa atcgtttctt ctgcttcagc agggattgct caatctgttg ctgctttaat
     3601 cggacagggc gacatgtacc atgtctatca tccctataca gaaaaaatcg ctagacggga
     3661 aatcatcata cctaagggac ataatgtaga ttatgggaca ccggttgaag taatggttgc
     3721 tcaaggtgga ggaaaagtca tagaagctgg ctatgcaaat atgtgtacac cggaacatgt
     3781 ttccatgatg attacggaaa aaactgctgc gcttctatat attaaaagtc atcatgcagt
     3841 tcagaaaagt atgctgacgg tggcagaaat ggtagaagtt gccaaagctc atcgtttgcc
     3901 attgatcgtt gatgcagctg cggaagaaga tttattcaaa tatagcgaaa tgggcgttga
     3961 cttagtgatt tactctgggg caaaagcaat cgaaggtccg agtgccggac tggtcatagg
     4021 aaaaaagaag tatattcaat ggattcggct acagtctaaa ggtattggcc gagcaatgaa
     4081 aatcggtaaa gataatattt taggctttac ccaggcacta gaagattatt taaaaaatgg
     4141 gagcgaatcc ggtgactcca tgaagcaacg attagcgcct tttgttaacg caatcaatca
     4201 acttcctgac ctttcagcga aaatagttca agatggtgcc ggcagagata tttatcgagc
     4261 aagtgtaacg attaatggcg ataaaagtgc gaaagaagtc attcaggaat taaaagcacg
     4321 aaatccagca gtctacaccc gagaatatca agcaaataac ggaatcattg agttcgacat
     4381 tcgttccgtc agccaaaacg aaatggaaaa aattataaaa agattgagag aaatcatgta
     4441 ggaggctttt aaattgtcag ttatcccaaa ttattataaa aatcgtgtat gtttaaatgt
     4501 attagctcat tcagttgaaa atgcaaaagc atgctatgaa gcagcggaag ggcatgtcgt
     4561 actaggtgtg ctatcgaaaa attatgctag cgatgaagca gcaatcgaag atatgaaaag
     4621 gtaccaagac gcaaccaata atgcgttgtc agttggatta ggcgctggag atccaaacca
     4681 aagtcagatg gtttcgcgtt tatctggggt tttacaacca caacatgtca atcaagtatt
     4741 tactggcgtg gggacttctc gtgctttatt gggccaaaat gatacagtca tcaatggatt
     4801 ggtttcacca acaggtaaga tcggctatgt caatattgct acaggtccgt taagttcaca
     4861 agcgccagca gctgaagtgc ctattgaaac tgccattcaa atgctgcaag acatgggagg
     4921 tacttcaatc aagtatttcc cgatgaaagg cttagcacat agggaagaat ttaaagcagt
     4981 tgcggaagct tgcgcaaaat atgaattcta tttagagcca acaggaggaa ttgatctttc
     5041 aaactttgaa gaaattctga aaattgcaat cgatgcaggt gtaaaaaaag tgattcctca
     5101 tgtttatagt tcaattatag ataaagaaac aggagatacg cgtataggag acgtaaagat
     5161 actattaagc atgg
//
LOCUS       DADVXK010000137         5085 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.140, whole genome shotgun sequence.
ACCESSION   DADVXK010000137 DADVXK010000000
VERSION     DADVXK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.140"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="KB909_002623"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="KB909_002623"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBB6838584.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="KB909_002624"
     CDS             complement(1297..2133)
                     /locus_tag="KB909_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838585.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="KB909_002625"
     CDS             complement(2317..3534)
                     /locus_tag="KB909_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6838586.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="KB909_002626"
     CDS             complement(3683..3862)
                     /locus_tag="KB909_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838587.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="KB909_002627"
     tRNA            3917..4000
                     /locus_tag="KB909_002627"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="KB909_002628"
     CDS             complement(4240..4818)
                     /locus_tag="KB909_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838588.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1569 a         1042 c          811 g         1663 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagtt
//
LOCUS       DADVXK010000138         5067 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.141, whole genome shotgun sequence.
ACCESSION   DADVXK010000138 DADVXK010000000
VERSION     DADVXK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.141"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..436)
                     /locus_tag="KB909_002629"
     CDS             complement(<1..436)
                     /locus_tag="KB909_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838589.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFE"
     gene            complement(743..1840)
                     /locus_tag="KB909_002630"
     CDS             complement(743..1840)
                     /locus_tag="KB909_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6838590.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            complement(1948..3975)
                     /locus_tag="KB909_002631"
     CDS             complement(1948..3975)
                     /locus_tag="KB909_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6838591.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            complement(4120..4851)
                     /locus_tag="KB909_002632"
     CDS             complement(4120..4851)
                     /locus_tag="KB909_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6838592.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
BASE COUNT         1432 a         1024 c          804 g         1807 t
ORIGIN      
        1 tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat actttataag
       61 ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata tatttttcct
      121 gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga gataacagag
      181 ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg acggttactc
      241 gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg atcgtttttt
      301 tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac tctgataaat
      361 ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct ttgcttaaaa
      421 aaaactcata attcattagt catcagctct ttctacgtat attactttcc atgcattcac
      481 caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca gcgattcttg
      541 tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt tttatttggc
      601 ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc atttttatta
      661 ataaaatggt atattttata ttgttataaa aagagcccaa ccatcctaca ataataaaaa
      721 tttactattt gttatcttaa ccttactttt ctttctcttc tttttttctc aaaacaaaca
      781 aaagtatgca taataaaata aacaataaga aaagtgaagc tactaagata taaatccaat
      841 tattgtcttt tttaatcgta acatccgtcg tgttcaattc cttggctact tttccgtcta
      901 ttgtaaaatc tttttcaaat acccattgat tggtatagtt gatcgtagta tttccttttt
      961 ttctcgaaaa ttttccattt tcattttcat ttcctaaaac agtcattgta aggtgatatt
     1021 cacctggggt tagcggttga ccatttaaag cagttggaaa agaaaaattt gtattcggcg
     1081 caatctgcaa tccttctttt tcctcttgat ataaaacttc agaatgtcct ttttttgtaa
     1141 tttttgtttc aataactact tgattgatat aggttttttg atcattttga acgtttgcta
     1201 agatgacatt tcttgcattg atttgatctg gtttaacttc atgaagagta aggttcggag
     1261 caacttcgtt cagtgtctgt tgcatcaaca aagcaataat ataggtgtat tcattctcaa
     1321 tcgataagct ttgatcctta gtttctgttt ggtccttttc cgtctggatt tcttggaatg
     1381 tgatcccacc agccaataca ccatcaaatc gctcattcgg catcctgaca tgaaaagcaa
     1441 cggtttggac acttttaggt tttagcgtca ctatctgtgg atagctcaca taatctacca
     1501 gatcaaagat caggctcatg tctttttcaa tctcgttttt tccgtattca accatcacat
     1561 ttgaattggt ggttgcgcta ttcacagaaa tatcgatttt cacttctttt tctgtatcat
     1621 ttctcaattc cgcttttact tctacttcct gatccggatc aagttgaaga tcgaagtaag
     1681 tttttctctt gtcgatttga ttctctgaag ttatcggcgt cactgaaaaa ttaaatgcac
     1741 tagctgacac tgatatattg ttaaaaagtg cccctaaaat aactaggagt gttataaata
     1801 attgttgttt tggtctcaag aaaatcgctc ctttaatcat atgtaagaga agactataac
     1861 aaaatcttgt ctctgtggga cacaagagcc tatggtacct gtgcccttct tgaaactcaa
     1921 taattttgtt atattcttct cttcctgtta atttcctggg acatctgcaa gtatccaaga
     1981 tagtttcccc tcaaaggttc cgattctttg gttttctaca ggaatattta ttctgattcc
     2041 acgatgagct gtagaatcta aaagagagga caaatcgctt tcaccctttt gatcactttc
     2101 gaaaatcgta acagcggatg tccctataac cgttgtattt tcagaggtaa caaaggaaag
     2161 agcttctgga agctcaaaat ctccatttgt aagaactttc tcttgtttca attgtaattt
     2221 ccaacttcca aaagcccgtt catctataat tttcaaccca cctgaaaact gtccgaattc
     2281 acttaatggt ctactggata ttttatgttt tccaaaattg acatattgag gagcagttga
     2341 gagataaagt ttgccttttc tgtaataaaa atagatatcc tctgtatttt cggagaagat
     2401 gccttctgta ttcgctgaat ccgagtcaaa aacataccct tcaatatcaa taggagtttc
     2461 tttatacttc tctcctattt tcccagtgat tgttttcatt tcagcaatat caatctgact
     2521 gtctttatct ttataataaa catggatatc tatctccttc agctttgcga tctttaggtt
     2581 tatttcattc gattgctcaa tcaaattccc gttttcaagg tattcaaaat gcatagtgag
     2641 tactttttca ggaattactt cctgcaaagt tgtctccaat tcgattatta acgtatctcc
     2701 agcaataaaa taatctgtca gatttagcgt gactcgattt ccggttatca agatatcttt
     2761 ggcatcaatt tgatttccat tgatcaagat atgctcggga atagttaatt cttgtgggag
     2821 gtcgatacta gtctgcattt tcttatattc aagaaaatcc ccctcgacct tcaatgtatt
     2881 tctgatagtt atcttatcgt ttcctccagc ttcagcgatg gccccataat cactatcgtt
     2941 gacttttaca tcagctgttg atgtgacatt cgatggaagt cgcgtgacag cgacagcatt
     3001 ttcttgaaaa aaagtacctg ttgaagaagt aaacccccaa tttacttctg tagaaccaaa
     3061 ctgcctaatg agatcaggta taatccgaga agagcgaccg acaccttcca aatcataagt
     3121 aagacttctt tgctccgcgt cccatttaat tattaacaag cgccatgtgc cattagaaag
     3181 aaatgtagga gctaccgtca cgccagtatg ctctccagaa taattattat tatttggttt
     3241 aggcgtgaca aaagcgacat gtccatgccc tctattatca gcagttatct ctcgatccat
     3301 tcgatcagaa gaaccactat ttttatacgt atcaaactca atcgagagcg cattcgcaat
     3361 gtaaggttgg ccagaacgag tagaatatga gccaattccc atacctggcg atccaataac
     3421 ttgactggga ttactagcca ttctaggatc gccagtcaat gtaaaggtca tgccatctcc
     3481 cgctctatct cgttgatttc ctaagtataa ataagattta aatgtaaaat ccgagagtaa
     3541 actaatcttc ttatttgacc aaatagctcc tctttgagac ctttctgctg ggttcaactg
     3601 cagtaacttc ccattttcca atatggacgt gctagtaccg ataggtgttt gaaaaatttt
     3661 atcgatagaa ataatattgg gatcgtcagg cagctcaacc gcagaaattg gtgcatcttc
     3721 tagtccttgt ttgtccgaac cctcagcttc tacgttgtca gtggtctctc cactactcga
     3781 aatacttaaa tcctcactgc tttcttgtgt ctggttggat tctattaaac tgtcgaatgt
     3841 cgaagtgagt ttgctttctt cgtctcttct atttccatgc tccaactgat tcaattccaa
     3901 agagtaccct atgatcggaa agatattagt cactaagaga ctgcttaaaa tgagcacgat
     3961 cctcctcttt ttcaatatat cttttcctcc tgatcgttaa attcctagat gaactattcg
     4021 tatccaaaca aatttagcct agcctttgac aatttttgct cgattacctc gcaagacaat
     4081 atgactacgt atttattttt aacagttctt ttcagtaaac tagttgttag gtgtatcttc
     4141 taatgtccaa actaatttag tggaatattg ttgcgctaac ttgacagatt taccgggtac
     4201 cgaaagctgt accgcatctt gattttcatt ttcatttgca ccaaatcgat agacccaagt
     4261 ccccacacct gttcctgatt tagcattaat tgctaacgta ttgtttcctc ccggtgtcaa
     4321 cgttaattca gaattcaccg tttgcggcgt atatgttgga tcaaccaaag aaacagcctg
     4381 ccctttcgta aatttcagct gtgctccaac tagttcatcc ccactggcag ttttaaactg
     4441 ttctggttga gagacactta atttccaccc agataaggta cttctcctat ctgtcacttg
     4501 gacatatgtc ggttttctag acccatcgtt catcacatca gcagctgcat aatacgtttt
     4561 atccgcagta gaaatttttt gagtcccaaa tttgaatttt gatccataat caatcgataa
     4621 tgcccctcct gttccagggc ttggaggatc tgatggatcg acaggtttat tgggatcagg
     4681 attctctgga tcaacaggag gagttacacc ctcatctcct gcttcaaatg taatcgttcc
     4741 ttctgtgtta tattcctttg ggtatacttc agttgcagaa acaaaagtcg tacttgctac
     4801 catgctgaat aacatcattg ctgctgttaa tacgatttct tttttcatca ttgacattcc
     4861 tctttcttta tttactaaac atatcagtcg attggattaa tccatagcaa aattctgttt
     4921 tacgatactt atgaaataaa agaacataga cctatatttg gtcctatgta tcgattagtt
     4981 ataaatgatt atcagcccga tttgatttct agtttttatt gcaacttgat gcaaacacaa
     5041 tctagaaata cagctgtcat agccttt
//
LOCUS       DADVXK010000139         5025 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.142, whole genome shotgun sequence.
ACCESSION   DADVXK010000139 DADVXK010000000
VERSION     DADVXK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.142"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            283..522
                     /locus_tag="KB909_002633"
     CDS             283..522
                     /locus_tag="KB909_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838593.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="KB909_002634"
     CDS             complement(884..1144)
                     /locus_tag="KB909_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838594.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="KB909_002635"
     CDS             complement(1329..1826)
                     /locus_tag="KB909_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBB6838595.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="KB909_002636"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="KB909_002636"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBB6838596.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="KB909_002637"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="KB909_002637"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBB6838597.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5015)
                     /locus_tag="KB909_002638"
     CDS             complement(4548..5015)
                     /locus_tag="KB909_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838598.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1043 c          771 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaa
//
LOCUS       DADVXK010000140         4969 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.143, whole genome shotgun sequence.
ACCESSION   DADVXK010000140 DADVXK010000000
VERSION     DADVXK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.143"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            81..380
                     /locus_tag="KB909_002639"
     CDS             81..380
                     /locus_tag="KB909_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838599.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            645..1520
                     /locus_tag="KB909_002640"
     CDS             645..1520
                     /locus_tag="KB909_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838600.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            1517..1735
                     /locus_tag="KB909_002641"
     CDS             1517..1735
                     /locus_tag="KB909_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838601.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            1722..4349
                     /locus_tag="KB909_002642"
     CDS             1722..4349
                     /locus_tag="KB909_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838602.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            4364..4582
                     /locus_tag="KB909_002643"
     CDS             4364..4582
                     /locus_tag="KB909_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838603.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
BASE COUNT         1941 a          617 c          991 g         1420 t
ORIGIN      
        1 ttttttacgc aatttgtatt tatttgtact tataaaggta gaggagttat agaataatta
       61 attaaaaagg agaggttttt gtggaagcaa taaaattaat gatttcagaa gaacaggagg
      121 aaatgtttct aaagcagttt tatcaaattg ctacaaaagc tattgaaaag gctcaagaaa
      181 atgcggggat gacaagggaa tatctcaatc aaaaagaaat ggcggaatac ttaaatgtga
      241 gtgaaaactt tttaaaaaat gctgtgagaa atgagggatt gcccgtagtt gaattagggg
      301 caagaaaatt ttattcgaaa aaggcagtta atgagtttat gtttgctcga atgaaaagag
      361 gggaaaatat tggaagatga tgaagtagaa attataaaaa aatgctttaa aaaaagaaaa
      421 aaagtgttcc caaaagtttg cagactgggg gaacactcaa taataaagtg ctgagaaaac
      481 tttatttata gctattatat caaaaaagaa ggtgaaaagg tgttttcttc tggaaatgtt
      541 gtagttgaca aacttagaga aataaatttt gacggaaatg taatccacac acatggtacg
      601 atcaattaag aaaaaaaacg aaaaaaggtg ttgagaagcc ctatttgaat gcaatagtta
      661 tcttagcaga aattacctat tggtatagac ctaaaaaaat ttttaacgat gatggtcagc
      721 tacttggtta tcaaaaaaag tttcttgaag atattttgca aaaatcatat aagcaattaa
      781 gcaaaaaaac aggattatca gaacgagcta taaaagatgc aattgtgtac ttagagaaaa
      841 aggggattat caaaagggtt tttagaaata tttattatga gaaaagagca gttacattat
      901 caaatgttat gtacattgtt ttaaatgtac ataaattgat agaaattact tttcctactt
      961 tggattgcga aaaaaaggag tatatgccga aaattcgtca gaggggtatc gaaaaaaaga
     1021 gatatgtctc tttaaaaaaa ggtagaggta tgtacaaatt tgtatatacg tatacaaaga
     1081 ctacttcaca gaacatatca aagactactc tcgttatgga agaagaggat attaatataa
     1141 agaggattta cagtaagatt agtgttcttt atgacgcaaa taacgaagat ggtcgaaaat
     1201 tatttcaagt gtatcactat ttgagaaacg ctaatgtaga tacagaagat atcagaaaaa
     1261 tcattgaata tttatctgaa aatactcagt atcttattgc tgagtgtatt ataaaacaac
     1321 atgaagcatg cttttttcaa agaaaaactg aagaagggtt atacgattat gtaacatatt
     1381 ttttgaatgg acttcagaaa agatataaaa gtcaattttt agaaaatgta gagcctatag
     1441 atcagttcaa aaaagctttc gaaatcaaag agttacctga aattactatg cataattggt
     1501 tgaaaggaga agaatcatga ttaaaaatcg cttaatagat caaatgtggt gtcttgatca
     1561 aaatacagat actctcgaat taatcgagag tatctgcttc aacacagtag ttctcgattt
     1621 aagagctgaa aatgacaatt gtgtaactca tatcataatt aatcaaaaaa tggctcagca
     1681 gctctctgag agcctaagaa aatgggctga aggagaaaac tatgaaagca attaaagaaa
     1741 aaatcgttag tagaaaaata aactggttag cactcagtgt acttgtttta atgattagcg
     1801 ttgtttttac aagtaatatt gttgaagcta gcattttcaa ttggtttgat gacacaaaaa
     1861 gtcaaacaga gtttttgaat aattctcttt atagacctta cctaaaaaaa tacaatggag
     1921 atttccttag tcagttcggg atttggcttg gatgggctgt ggtaaaaggc atgtttactg
     1981 tgactgattc gattcaaaat atgattccag atgtgttgga tttgttcaat ttcattgaaa
     2041 gtacagggct aaataatgtt tatcaatcag tcataaatac aattgtcgtt ggattaatga
     2101 tcctttcatt gatgtttgtt ggctacaaga tgattactgg aaaaggaaca atagatttaa
     2161 gatctgttgg aatgaatata gtgatgtctg tagcgttaat tcttttaatg ccaacaatga
     2221 tttctagcgg tattcaattt gccaaaatat tttacaatga tgctactacg attacaaatt
     2281 cagatgacgg agtcgcttgg tcattgataa aacaaggagt aacagatctg gcatatatta
     2341 ataaaacaga tcaatactca agcattgata aaacggagga tcgaaataag ttaacacgaa
     2401 aaaattttca acagacagat ttaacacaag tgttgacgga taaagtgatt gataaattgg
     2461 aaaaagaaaa tccagctgcg gataatcttc gctatgaatt agttgaaaat tctaataatg
     2521 aatttgttgc cacaaagttt tctgataact tcttatcaac attttctgat agcttgaaat
     2581 caggttatta tcgatatcaa gcaaatcttt gggggatttc gattgggttg acagcgttgg
     2641 caatcgccta tgtgttcagc gcgtttgtga tcattacagc aatattagaa cttgcattta
     2701 aacgtgtgtt aggtgttctt gtttttgcga cagatattga aacaggacaa cgttcaaaag
     2761 ttgttttatc cgatatttta caatgttact taacagttgg atttcaaggg tttggactat
     2821 ctatgtttgc tatgtttatc aattttttaa atgctggaca aggtatctcc acaaatattt
     2881 ttataaaaac aattgcttat atctgtgctg tgtttgtgct gataaaaggc agtggaacag
     2941 tcatgagata ctttggtgtt gatattggac tcaaagaagg ctatgggcaa cttgcttctg
     3001 cttttggtat gggcgcaatg ctgtttagaa aaggatcaac tggatttaat cgtgctaaag
     3061 gaagcggaaa tggaaatgga tcagacagtg gagaaggaga agatcgaaaa ccagaaaaga
     3121 atttcggcga aactctatca aaaaaagctg gcaaaactgg aagagctttg ggatatgccc
     3181 atgaacgtgg attatcaggt ttagcttcag atggagctac aatggctagt gaaagagcaa
     3241 taaaaccatt taagagtatg cgtgatatgg ctaatgatac caagaataag ttcaaagaag
     3301 gtttagatga tggtacagtg tccgctatta ataaaaatag caaacctatg ttagctaaaa
     3361 ataaagaaga tgaaactgga aaatatgctg attccatgcc aacacgtctt tcggatagaa
     3421 aagatggtgc taaggttgaa aatgccgata gaattatgtc tagttctgaa cgtatgcgtg
     3481 aagcaatgaa aaataatgct gaatcgaata ataatcctgt aagtgcaatt cagcaaaaag
     3541 ttcaacaaga tattgaagaa cgtaaaaatg ctatgcacgg tcaagctaag tctgctgaag
     3601 aattaattaa tcagaagcga caagaagcta aatacacgcc tgaagcaatg aatcgtgagg
     3661 aaatgttaag gaaacgtgta gaagggcgta caggagctaa tacggacgaa aaagaagcgt
     3721 tgaccaaaga aagaatccaa gaagctaaaa actcaaatac cggattagaa aaattggtca
     3781 aagaaaatct acaaaattct acaagtagtc aaggtggccg atcagtagat gtccgagaaa
     3841 atattcaagg ttcattgaat ggtcatgtcg gacggaatgt tgatgtaaga gagaatttac
     3901 aaagctcttc aaatggtcaa ggtactaaga caattgatgt tcgagaaaat gtacaaaatt
     3961 ctacaagtag tcaagggttt aaatcaatgg atgtaagaga gaatgtacaa aattctacaa
     4021 gtagtcaagg gtttaaatca atggatgtaa gagagaatgt acaaagttct acaagtagtc
     4081 aaggattcaa aacagtagat gttcgggaga acgttcaaaa agatagtgga gaaatgaaag
     4141 aaaaaacaca aaaaatcaat atcgttgaag acagaaagtc agcgaaaaaa tttgattcaa
     4201 atcatgaaac agtgattatt gatagtgaaa tccgtgaaaa tgataaggga tcaaaaccaa
     4261 gacgaagatt tacctatgaa gacaacgagt tattcagaga tacacttaat gatcctaatc
     4321 cgcttttcga taatctatta aaaaaataaa agggggaatt gtcatgaaat taattctaaa
     4381 gattagtacg catgatttct tagaacttga cgaattatgt gaatcagtaa agaacgcaac
     4441 aaatgaaaaa atcacggtca ctaattatat tgaactgatg attcaagaag aattaaagat
     4501 gaaacatgag ataaaaaaca acttgaaata ttgttatcta gaaaaaagtg aagagataat
     4561 ccatgaatta aatggctttt aaaaattgta tttgacatga atttacgaca aggaattagt
     4621 ggggattaag cgattattct cttccacttt agagaaataa tgggttaaaa agccagaata
     4681 cgtagagcaa tattgacaac ctataaagga gctattgttg aaaattgaag taacaaaaag
     4741 ataaagggag gtttacatct atcagattaa aagtgatagt acacccatga aacctgcaaa
     4801 agagttgaac ctaatgtata tcggtttaac tctttttatt tgcaaattaa aaaaatatca
     4861 ccgaagtgac gaatgaaact atgaccaaat taagcaagaa aatatatctt gcaaataaag
     4921 tagtataaaa agatattgat aaagccaatc aaaactttga atttcaaac
//
LOCUS       DADVXK010000141         4933 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.144, whole genome shotgun sequence.
ACCESSION   DADVXK010000141 DADVXK010000000
VERSION     DADVXK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.144"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            85..972
                     /locus_tag="KB909_002644"
     CDS             85..972
                     /locus_tag="KB909_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6838604.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="KB909_002645"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="KB909_002645"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBB6838605.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="KB909_002646"
     CDS             2274..2720
                     /locus_tag="KB909_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6838606.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="KB909_002647"
     CDS             2993..4345
                     /locus_tag="KB909_002647"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBB6838607.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="KB909_002648"
     CDS             4516..4803
                     /locus_tag="KB909_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838608.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DADVXK010000142         4912 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.145, whole genome shotgun sequence.
ACCESSION   DADVXK010000142 DADVXK010000000
VERSION     DADVXK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.145"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="KB909_002649"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="KB909_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBB6838609.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="KB909_002650"
     CDS             complement(2066..3064)
                     /locus_tag="KB909_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBB6838610.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="KB909_002651"
     CDS             complement(3290..3943)
                     /locus_tag="KB909_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBB6838611.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="KB909_002652"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="KB909_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6838612.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1455 a         1022 c          754 g         1681 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttttaaa
     4801 aaaatgaaag ttatctaagg ttaatataca gtaaaaccag cattctcgct ttttttatca
     4861 tttaaaaatt agagttttca aatctaattc aaattttcta aacatatgaa ac
//
LOCUS       DADVXK010000143         4862 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.146, whole genome shotgun sequence.
ACCESSION   DADVXK010000143 DADVXK010000000
VERSION     DADVXK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.146"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(173..1192)
                     /locus_tag="KB909_002653"
     CDS             complement(173..1192)
                     /locus_tag="KB909_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6838613.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1189..1413)
                     /locus_tag="KB909_002654"
     CDS             complement(1189..1413)
                     /locus_tag="KB909_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6838614.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1410..1703)
                     /locus_tag="KB909_002655"
     CDS             complement(1410..1703)
                     /locus_tag="KB909_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838615.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1740..1877)
                     /locus_tag="KB909_002656"
     CDS             complement(1740..1877)
                     /locus_tag="KB909_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6838616.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1879..2310)
                     /locus_tag="KB909_002657"
     CDS             complement(1879..2310)
                     /locus_tag="KB909_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838617.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2324..2818)
                     /locus_tag="KB909_002658"
     CDS             complement(2324..2818)
                     /locus_tag="KB909_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838618.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2818..3267)
                     /locus_tag="KB909_002659"
     CDS             complement(2818..3267)
                     /locus_tag="KB909_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838619.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(3271..3891)
                     /locus_tag="KB909_002660"
     CDS             complement(3271..3891)
                     /locus_tag="KB909_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838620.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(3891..4799)
                     /locus_tag="KB909_002661"
     CDS             complement(3891..4799)
                     /locus_tag="KB909_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBB6838621.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
BASE COUNT         1327 a         1050 c          764 g         1721 t
ORIGIN      
        1 aagccataaa caatcaacca gtagaatgtg tggcaacaaa cctgttatcg catagcttgg
       61 agtgtgacta ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaatga
      121 tttttatagt tgtcaatata gttatgtaat gctcctcaac gaggagctat ttttatcgtt
      181 taggaatatt taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc
      241 cctctggatc attcgttgcc cgcatcatga catagacttt cttattaggg aagttacgca
      301 tgttaaaaga tacatgatag ccaacatttc cagaagtatt ataagcttga tttacatctg
      361 ctctataaat tccatcagct cttactcgag ctaattcttt cccagtattg taatccataa
      421 tgaagatata ctcgtattta tagttagcaa tgtgccatcc agctacatgc aaatttgcat
      481 tttcgatttc tccaaactga tcaatgtggg cgtaattcgt tccatctgtc agtgtaggat
      541 tagctgcacc agctcgtgtt ggatcaatga caggcttgtt ttcagaagtt gttggatttt
      601 catcggtaaa tccatgagct aaatcatatg ctaatttttc tttacttacg cccatttcag
      661 aaagataacc gtaaggatct gtatgatcgc cccagatgtt ttgtgttacc cataaatgcg
      721 atttgattcc cggttggtta taaggagtgt ccaacgttaa tggaatacca tatttcattg
      781 ctgaatctct agccaattca acgtatgcct tgtagttttt ctcaaacgtt gctttatcat
      841 gtgtgtgttg taactcaatc tgcacaggac tgttggcatt agcatacgaa ccagcaccgt
      901 actgtacata accaggttga ccgacttgat aaacaattcc gccgtctccc acaatataag
      961 cagtataagc gctagtccat gaacgttgca tatactgcgc ttcattgcgt cctgttgctg
     1021 tttcattagc cgtttcatgc agtaaaatat actgattatt tgctacttgt gagctacctt
     1081 catttgcgcc caaattaaat tcattgttga tagtataggc aaatccgtta attggcaata
     1141 aaaaaagagc cgttaacagg ctcatcgcag taatagtaat tttctttttc atttgtttcc
     1201 tccttcttcg ctttcagccg agaacatttt gtaggttcga tttgatacac ccaacacact
     1261 ccctaaaaac gcgccaaaac cagtaatgat gacaacacag atatctgtgt actgccaatt
     1321 gagcgcttta ccaactaacc ccacgaaagt agctagtgcg ggaataatta ccagtgcgaa
     1381 ccattttagt acttcgaacg ttttattatt cattttcttc tctccctaaa caaagttttg
     1441 atttgttgcg tgtgttccac caatttttct gtatgtgtat ctaatctttc atcgtgtttc
     1501 tttagttctt catgaatcat caatcgatct gatttgctcg attctaaatc tttagtcagc
     1561 aaatctaaat tgtggcttac ttttgaaaga gtctcagtaa ttttcgagaa agatgcagca
     1621 atcggtctaa ttactaataa aatcaaagaa acgatagcgg ttattgatcc tgctatcatt
     1681 ccccattccc ctaaattaat catgtgacaa ctcctttacc ttaaataaaa acgcatcaat
     1741 taagatgcgc tcttatcttt attaatgatt ttatctgctt cttcgtctgt aatgcataat
     1801 ggaacgaaaa ccattacttg ttcgttagtg aaacagcccc agtcatacat tagtttgata
     1861 tcttcatatg aatacatgtt acttcccacc ttgtaattgt tttttgattt cttcgatttc
     1921 cttggtattt tgtacagaag caagcatcgt ttttgaattc aactgcgcta aactttctga
     1981 cttttctttc aataagacat tttcttgctt gattgctaca ttgtttagca ttgctttaga
     2041 atttagctgt ttcaattcat cattttctgc cttcagcgtt tcgtataatg ccttaatatt
     2101 agccaattca tctacgctat caacagcatt cccttttttc tcttcttcag tagctaactc
     2161 aacccactgt tttttatcaa aatcaaatct tggtctccag ttaggaactg gtggtttaat
     2221 ctctgtacag ttttcaggga tattttcttg attgttcaaa atgatttgct cgaatccgta
     2281 aggcttgatt gatttgtaaa ctactttcat tagatttcct cccttaaatt gaataagtga
     2341 taacaaatga ataagctgat ccataacttg aatttcttct ccatttaatg gctccgtctg
     2401 cgccaataga tagttgagca ctgttcaaag tagaacggtc tattgaccca accagttgtt
     2461 caaaactaat tggtgtccga tagccttctg gaacagttaa aataaccgaa tcattcccgc
     2521 cactactttt tccgtttaaa gccacaaaat atatagaaac tgtttttcct tcacgataaa
     2581 gctttgctgt ccctgtatta ccgttagtga caaccagatt taccacttca tatctgttat
     2641 catcagtcgt caaaacacgt ttattattga ttgttacaga acctgaaaaa ttcttatgtc
     2701 ctgcaatggc ttggtctcca tctgtctgca ccaatgcttc tttaccatca atagcttcta
     2761 catgcgtttt taagtattta gcaactccgt cttcttttaa ttgaacaata tcagccatta
     2821 aaccgtcccc actttctcaa atgtaatatt cgctaatcca tcaagtttca ctttatcggt
     2881 tgctgacatt aaacctgctg tcgtagttgt agcattacct ggatttttct gtgctccagc
     2941 tgcaattcca tccaacttag ttttatctgt ggacgacatc aacccatttg ctgtagttgt
     3001 agctacagct gtagttgtgg catttattcc aggatcacct ttatctccct ttggtaaaac
     3061 aaaattaaat ctagctgcag atgatgttcc tacattcgta acagaagcgg ttgaaccact
     3121 agaaacggtt cctatggtaa ttgttgctgc ttggccagga tcgcctttat ctcccttcac
     3181 cgttgttggt ttgccttcta tagcattcca atgagtttgt ggataaacct gtacattgct
     3241 ttgttttatt tttacgatat ctgtcattct ctatacctcc ccaatttttt caaaagtaaa
     3301 atttggaatt ctttcgtttg tgtaattttc tgcttgattt acagcttctt ggaatttttg
     3361 atctacatat gactgattga caccaccagt cccactacca cctgtagaac taattgttcc
     3421 atcttcatca atagtgatgt tttctccagc agtataattt ttcagtgaat cgagtttttc
     3481 ttttaactcc agcgaaaaat tgacatcaga ttgtctgact gcagagactt tccctgtctc
     3541 atcaatcgtc aataattcac caacttttat gccacccaaa cggtcgatag tggcaactgg
     3601 caacacgtag tcaccttctc cactgtttaa aattttttga tacatttctg ccgtgataat
     3661 gccgtcatct tcttcacttg catagggtaa ttctgtgaga acattctcta atcccaaatc
     3721 ttctttagta atgacgacgg ctccaatttt tccattaaca gataaaactg ttgcttctcc
     3781 tgctattatt tcttctaacc caagaactgc ggaagcatgt gtgattggaa agaattggcg
     3841 ttgtacaccc gttttttcat ccgtttccat cattcgttta gttttagcca ttagatcacc
     3901 ccaactttct caagagtgaa cacattttgc tttggatcat caacggttgc gatgatcaag
     3961 gctccttctt caatcgggaa tgctacagtt ccaacttttt cgacttcatg attatctgaa
     4021 aagagatcat cctgcaaaat atcagtcact tcaatctccc cgtattcaat cgtgaaaagc
     4081 gttgctcgca atttctgata taaatagtcc atatctgcca gcaaacgctc tgaaatagac
     4141 gcatgacgaa ctccttgaat atctactcgc gcatccgtta gttcggctaa catgactcca
     4201 cctggatcaa tcgtctttaa aatatccttg attgattcaa accatgccaa atagtctgat
     4261 tcttgtcctt ctctccaatc ttggaaactg tgttcctgtt cttgtctcca acgttcaaat
     4321 tcttctttcc tttcattcat ccagtccgta aaatcgcctt tattttcatt aataaagtcc
     4381 gtcatatccg caattaaatc ttcgattgat tgccaataag aacccatttc tccttctgtt
     4441 tttgaaacag cattaatgac aaaataagag aagtcttgag ttgttccaat caagtcttct
     4501 cctttaaata taatgaaatt ggctgtttgt cgatgtaaac actgcatgga atatttatca
     4561 aaaatatagt taattttccc ttttttagca tccacaattt ttgtttctaa ttggactgga
     4621 tatttcccac ctacaactga ttcaaaatat accttacatt ctgataaatc gtagggaaga
     4681 ccattttcaa ctatagtcgc ttccataacc tctgtattct tattgccttg tcgaacttga
     4741 atcatcccca cgtaattata gggttctgtt gtacttaata tgacattcca ctttgccatt
     4801 aaatcacctc cctattttgg tggtatgaca atggaagaaa ttgcacttgc actataatac
     4861 tg
//
LOCUS       DADVXK010000144         4766 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.147, whole genome shotgun sequence.
ACCESSION   DADVXK010000144 DADVXK010000000
VERSION     DADVXK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.147"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(207..1169)
                     /locus_tag="KB909_002662"
     CDS             complement(207..1169)
                     /locus_tag="KB909_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6838622.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="KB909_002663"
     CDS             complement(1171..2610)
                     /locus_tag="KB909_002663"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBB6838623.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="KB909_002664"
     CDS             2795..4741
                     /locus_tag="KB909_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBB6838624.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1515 a          817 c          790 g         1644 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatgga
//
LOCUS       DADVXK010000145         4761 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.148, whole genome shotgun sequence.
ACCESSION   DADVXK010000145 DADVXK010000000
VERSION     DADVXK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.148"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..191)
                     /locus_tag="KB909_002665"
     CDS             complement(<1..191)
                     /locus_tag="KB909_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838625.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(201..1016)
                     /locus_tag="KB909_002666"
     CDS             complement(201..1016)
                     /locus_tag="KB909_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6838626.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1278..1721)
                     /locus_tag="KB909_002667"
     CDS             complement(1278..1721)
                     /locus_tag="KB909_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBB6838627.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1855..2193)
                     /locus_tag="KB909_002668"
     CDS             complement(1855..2193)
                     /locus_tag="KB909_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6838628.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2181..2558)
                     /locus_tag="KB909_002669"
     CDS             complement(2181..2558)
                     /locus_tag="KB909_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6838629.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2782..3975
                     /locus_tag="KB909_002670"
     CDS             2782..3975
                     /locus_tag="KB909_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838630.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4141..4563)
                     /locus_tag="KB909_002671"
     CDS             complement(4141..4563)
                     /locus_tag="KB909_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838631.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT         1399 a          902 c          826 g         1634 t
ORIGIN      
        1 atgcaacctg gaccaataaa aagtaaagaa aaaataaagg aaaagacatt ccttccatct
       61 atcgacaaaa ggaacgcagc tgctatatac aagatattga cacaccaaaa acaaaggcta
      121 cttgccaatg attgatacaa ccaataaaag aattccatat aaacattttt gtcaaaacgc
      181 tgctctttca taatcacctc ctattccttc attcctgatg aagcgatccc ttctacaaaa
      241 tatttttgca tcgctaaaaa tataaaagca acaggaagaa cagaaacaac tgaggcagcc
      301 atgattaatg cgtactctgc atcaaatagc ccaataaaca ttttcaaccc taactggatt
      361 gttttatttt ccgtagaaga caaataaatg aatggcccca tataatcgtt ccatgtatta
      421 acgaatgtga tgatcgtcaa actggcaatc gccggttttg taagaggtaa aatgatcttg
      481 cgatagattc cccactctga taagccatcg atccgcgcac tctcacataa agaatctggg
      541 atactactgt agtattgctt caacaagaac acaccaaaag cattgaacgc ttgtaatagc
      601 accaacgacc acaacgtata tgttaaaccc acttttctca tcataatgaa ctgcgggatc
      661 atataagact gccaagggac agcaatcgtg ccgatatatg ctaaaaataa aatatcgcgc
      721 cctttaaaat ttagtttaga aaacccgtaa gcagcaaaac tagaagtaaa caactgaatc
      781 aacgtgatca caacgcttaa aaaagctgta ttcttaaaaa atgtcactaa aggaatacga
      841 gaccaaataa ccagataatt ctctaaatgc caagttttag ggatccattg aatcggaatc
      901 gtgaacactt cattatttgc tttgaatgaa gcagaaacca tccataaaaa aggaatgatc
      961 gtcaataaag ctaatacaat cagcagaatc atacccaacc attgaataaa gggcatgttt
     1021 tttgaacgaa tttttgcttt ttttctttca tttcgaacac ctccaaagtt ataatcttca
     1081 tttctttgta atgattacaa tccagaacaa cggttattat agctgattca tttccgttct
     1141 tcttatgttt gtaagcgctt atttaacaag ttatgtaaat ctctttattt tttttgattt
     1201 aaaaatgaaa aaatacaaaa gcaagactgt catacgtctc gcttttgtat tgaaatttct
     1261 tcgattagag atacttatta ctgttcaaaa gcttctttga aacggtgaat caattcattg
     1321 actacaggtg ataaaatccg attctttttc cagactagca tgcagttcgt ttcaatcatt
     1381 gggtcaagcg gaacgaatgt cactcgcttt gaaagatgac ttacagcacc ttctatgact
     1441 aaagcagcac ctacctgatt ctcaattagc gcaaatacat tgaaaatcaa attgtacgtt
     1501 cctgtgatca gcaactgctc cttttttatg cctaaccagt cagcaaacat tcgctgtatt
     1561 tctggacgct ttgagatcaa aagaggtaca ttcgcaaagt cttcttttgt tatcacgtct
     1621 ttttttgcta aaacagaatt ttctaaaatg agcaatcccc atttttcctt tcttggtaac
     1681 aaaatcgttt cgtatttctc tgtatctact ggatctagca aaatcgctaa atctaacagg
     1741 cttttttcta gtcactccgt gatatcatca cttgttccgc tgtggatatg aaattgaacg
     1801 ctgggataat cacggatcaa cttttctagt aatagtgcca atgtattcga attatcagct
     1861 tccacacagc cgatcgtaaa tcggccgctg aataattgtt tttttctgtt ctcgaattct
     1921 tgagtggttt gattcgttaa atctaaaatt tcttctgctc ggctttttta gaaaataacc
     1981 tgcttctgtc aagatcattt tgcggttttc gcgtacaaac agttctgttc ctagttcctc
     2041 ttctaactcc ttcagttgtc ggcttaaggt tggttgtgta agatgtagaa cttctgcggc
     2101 ttgagagatt gttccttctt ctgcaattgt ccaaaaatat tttagtaagc gtaactccat
     2161 agcgatgctc cttgattttt ttacttgata cattccattt tatttctaga taacacacga
     2221 tcatatttct tgatttttcc ttgtaaacgt tccaaacact cttgcatttc agcaatttct
     2281 ttcgtcaaaa gttcactttc ttcaatcaaa agcttacgcc gctcaaatac agttgcttct
     2341 ccttcgctag ataggcgaat atattcaatc aaagactcga tcgataatcc ggcatttcgc
     2401 atacagatcg taaagtcgac ccattttagg tcttcttctg tataatcacg gattccgcct
     2461 tttgtccgat taactggtgg aatcaacccg attcgttcat aatagcgcaa tgtatcggcc
     2521 gaaatgccct tttcttcact gacttgtttg atattcatct gatcactctt tctcttaatt
     2581 tcttgccact ttacttatgt attttattta ttctacaact ttaagtgtac tccaagtcaa
     2641 tactcatttc tattaaaact aagctggatt atctatatcg gttgtttgtg tattatttca
     2701 aataaaaaag tcttgttttt ttattctttt ttggatatac ttttaacaat ttagggaaat
     2761 tttaggaaaa ggggtataaa aatgacaacg tatcagcgaa aggtattatt atcgacatcg
     2821 gcgggaattg ctttagagaa tatggatatt atgtttttag ctttttcatt atcttcaatg
     2881 attacttctt ttcatattag tggtacgcaa gcgggtttca tttcaacgat cactaatttg
     2941 gggatgctca ttggaggtat tttttttggc atcatagctg ataaatatgg acgtgtgaaa
     3001 gtattttctc aaacggtcct tctgttttcg attgcttctt tattgatgta ttttgcttca
     3061 aacatctact tggtttatct ctttcgcttt atcgcaggtg taggagcggg aggagaatac
     3121 ggggcgtgta tgtccttgat ttccgaaagt ttttcaaaaa aacaaattgg acgagcttct
     3181 tcggttgctg gtattggtgc gcaggtcggt gcggctttgg ctgcgatttt agctgctgtg
     3241 atcattccaa cgtttggttg gaagatgttg tatgtcgtag gtgtactgcc ggtgttgatg
     3301 gtcttgttca ttcgtcgcgg cttgactgaa ccaaaggaat tcaaatctgt acaatctgcc
     3361 gaaaagaaaa ccaaacttag cagactgttt gaatcaaaac atcttgcttg gcaaacatgt
     3421 ggccttagta tcatggtaac tgtccaaatt gccggctatt ttgggttaat gaattggctg
     3481 ccttcaatta tgcaaaatcg attagggctt tcggtttctg ggtcttcatt gtggatggtc
     3541 agtactattt taggcatgtc tttggggatg atgacttttg gcataatcat ggataaattg
     3601 gggcctaaac tagccttttc tttgttttta atttgttcat ccttatctgt ctatctactt
     3661 gtgttagccc atagccagtg gagtttggta gcagccgctg tgatagtcgg ctactttatc
     3721 aatggcatgt atggtggata tggcgcagtg attagtagtt tgtatccaac agaaatccgc
     3781 gcgacggcga ataatttcat tatgaacctt ggacgagctg ttggtggttt ttcttctatc
     3841 gtcatcggtt tcttgatgga tcattatagt ttaactgccg taatcttgtt tttgagcggt
     3901 atttacctag tcagtctgct ggtcttgaca actcttactg gtgttacagc attaagggaa
     3961 agcttgcagc attgatagtt gagtctgtaa atgacaagaa agaggtgtgg caaaagcttg
     4021 catctgcggt aataagacca gccaaatcaa aaacatgaga cactgtttcc gtttggctgg
     4081 tcgtattact tgatgcaggg cagctttttc aactgctaat ttccttctat ctggcggcga
     4141 ctattctttg acgtccgtca tttcaaagta ctttactaat aacttagcat aacgaaaaac
     4201 tgtggataca ctcgtatatt gagcgtctgc ataatcttcc aaatttttct caggatgttg
     4261 atacatgaat tcaatcaaat gataattata tgattttctg tagaaatgaa gataaataat
     4321 gtagattggg aagttctcct gcttttccat agaaaagcgc cgattattct cattcttcaa
     4381 aatgacctta tcaggatatt tttggaacaa ttcttctaaa tctgttagat aattcaagat
     4441 agacttactt gataccttca attcgttttg tagttcttct attgaacacc aacgttctgt
     4501 ttcaagcagt aaatgaatca ttttaatttt cttttgagaa acttttgtta aaaaagtctg
     4561 catattttct cctcctgtat ctactttact atactacata caagaaaaaa aacggataca
     4621 aatatcatat tgtcacaccg tcaatagtgc ataaacctgt tattatttct ctttttttcc
     4681 taagtattct attgatatga atcatttaat cgtttattat ataaatgtca ataatctaat
     4741 aataaaataa cgtacatatt t
//
LOCUS       DADVXK010000146         4748 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.149, whole genome shotgun sequence.
ACCESSION   DADVXK010000146 DADVXK010000000
VERSION     DADVXK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.149"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..611)
                     /locus_tag="KB909_002672"
     CDS             complement(<1..611)
                     /locus_tag="KB909_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838632.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQ"
     gene            complement(759..1301)
                     /locus_tag="KB909_002673"
     CDS             complement(759..1301)
                     /locus_tag="KB909_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBB6838633.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1436..1825
                     /locus_tag="KB909_002674"
     CDS             1436..1825
                     /locus_tag="KB909_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838634.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1829..2593
                     /locus_tag="KB909_002675"
     CDS             1829..2593
                     /locus_tag="KB909_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6838635.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            2722..3669
                     /locus_tag="KB909_002676"
     CDS             2722..3669
                     /locus_tag="KB909_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6838636.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3799..4539
                     /locus_tag="KB909_002677"
     CDS             3799..4539
                     /locus_tag="KB909_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838637.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT         1649 a          783 c          943 g         1373 t
ORIGIN      
        1 ttttgtttgt tttttctttg ccacataaat acacctagac tgacgatgaa gagcatatcc
       61 aacagatttc ctgcgacttg gatcgtcgaa gggttggtca gtggcattaa agcaaggaca
      121 aaaaaggaaa acaagctgta aataaaacag gtgacaggaa ctaatcgaaa gaagagcgga
      181 catttcaatt ggctaaaaat gagtgaaaaa ataaaataag taaaaatgga taaaatcacg
      241 actaaaccat tcatgataaa gaagaaaagc gtattgtgat taaacgaata aaaaagaatt
      301 gctaaaaaag aaaacgtttt aaatgcaatc aatacgcttg aagcttcgtt taacgtacca
      361 ggatgtcgat gaaaaaaata ggcaccgaaa taaacagaaa acagtaagcc gcaaagagaa
      421 gacaaaatca aaaaaaacgg attttcttcg gcttctgtga tatcagaatg atccaaaagc
      481 aaccagccta atgcactaga aggcgcatgt gaggtcttaa ggtatgaata acatagaaaa
      541 aataagatcg tcaaagttgc aaaaaaagag cctaaatgta aaaaattagt ggttctacgt
      601 tgaatttcca taatatctcc aaattaaatt gataagtata taaagtataa taacaaattg
      661 atgagtatat gtcgatgttt tttaatcaaa ataataaata aaaactgtct aacatttaaa
      721 atttaattta gatattagac agtttttaag tttgtgagtt attttccttg tcgttttctc
      781 acttttttag tccagaaacc acctgaaata tattttggct cataagaaat gataaaagca
      841 cgctcttcga tttctttgat caggcgatac agttcacgtt cgctttttct aggagaaagt
      901 atttcgagaa ctagccgctc accttccagc cccattgcag aagtctgtgt cacaccataa
      961 ccgtgttctc tcagtatacc cggcaaactt ttatcttctg cgctatttgc tggcaaaatc
     1021 gttgtgacca tgatgtatcc taatgccaat ttgtcttcaa tcaaaattcc gacactgata
     1081 cctactgcgt aacctaacgc atagacaaat aaattcagtg gattatctaa acgatctaaa
     1141 acaagggata agccgacgat ataaatcgtg atctcgacca tactgacaag tggagcaatc
     1201 agtcgatagc ctttcattgt caacatgaaa cgtaacgtgt tcagagtgat ataagcaaaa
     1261 ttaatgagga agatcatccc caacattttt ggatcaatca tttgtaaaac tcctttcatt
     1321 tatataacaa caatatcaaa aaaaatcgta agtgaagaaa aattgaaact ttatacatac
     1381 aaaaaaatga taaaatgatt ataatagaat tataaagata ggttaggtga ttaaaatgaa
     1441 aacggtcaat cgtgtgtttt gtgccagcca cgtgctaagt ctccttctca gtatatactt
     1501 aggtgtctat tcgattcaac agccaattga ggtagagaac attgtttttc agatgtcgct
     1561 gacagatggt ttaattttaa gcgttttttt ctttttgata ctgtttattg gtaatatttt
     1621 cggtagcgtt gccagttttt tgaatttttc tatttatcca ctcctttcgc tagcattagg
     1681 agtggtggga ctttgttctc tgtgcttatt tcccgagcca ttcagtcctg catttatatt
     1741 atttggtaca ctgaacctgt tccagacaac tgttggagca tggttgctat ggcgatcagg
     1801 aaatttaatg aaaataggtg agtaacaatt gaatccaatt atattgaaac gttctgtcca
     1861 tcatattcca gtgttagaag ttgttctgaa agaattaaga gaggaacgta ttcccgttgt
     1921 catctattat cacggatggc agacaagtaa ggagttagtt ttgacgcaag gaagaaaaat
     1981 tgcgcagcag ggcattcgtg tgatcctgcc agatgcgatg aatcatgggg agcgcaaaca
     2041 gccggtttct tctattccat cctatacatt ttgggatagt atctacggaa atctgtttga
     2101 atttgacaca cttatcaagc atttagaaaa aagaggtctt ctacatgatc agcttgcagt
     2161 tggcggggtt tcgatggggg gaatgacaac atgcgccttg ttggctaaac atcctcatat
     2221 agtagcgggc gtgtgtttga tgggttcccc tgcacctttg gaatatggaa aagaaatcgt
     2281 aaggcgcgca tcggaatata attatgtcgt accaaaagac tattttgatt tgatttcatg
     2341 ggttaagagc tatgatttgt cattgcagcc ggaaaagtta gctggacgtc ctctgttctt
     2401 ttggcatgga caagctgacg aaaaaatccc ttatatacaa acggaacgat ttgtagaaaa
     2461 aaatcggcat aagtcttacg gaaaagaaat tgtttttcgt tcctcaaaaa cacagcgaca
     2521 tatggtacaa atacaactaa tggaagaagc ttccactttt ttagcaaaaa atttgataaa
     2581 aaagtataaa taattgaaac ggaaaatcac tcatgacgat agaggatttt ccgtttttta
     2641 ttttgggcta taataaactc tgttaggaaa atttggtata attgatagta agaatgacaa
     2701 catgttagaa aggaagagag catgcccact ttagcagatg ttgcaaaacg tgccaatgtt
     2761 tcaaaaatga cggtctctcg agtcatcaat catccggaac aggtgactga cgaattgaaa
     2821 gagttagttt tctcagcaat ggctgaactg gattaccgtc caaatattgc tgcaaaagca
     2881 cttgtcacga atcggtcgca gatcatcaaa ttatttatac tggaagaaat cgacacaact
     2941 gagccctatt acatgaattt gctgatggga atcgctaaac ggatcggtaa agcgcattat
     3001 tctctccaat tagttacaaa tgatgccttc gacgtcggtt cttgtgatgg atacatcatc
     3061 acaggtgtca gaaaaaaaga cttcgattgg atcgaccgtt tggaaaaacc agttgtcttg
     3121 tttggggaaa attctgaagg atatgattat gtagacagcg ataatgaata tggtacagca
     3181 aaagcaacgc aatatgcctt agaaagagat tatcaaacga ttatttatat cggtatcgaa
     3241 gtggacgagc cttttgaaat ttcaagggaa actggttatt tatctgtgat gaaggaagtt
     3301 gatcttccta gtaaaatctt gcggtttcca aatcattcga cagaagtaga aagatatatg
     3361 acagaaaact gggcagattt tacagataaa acttgttttg tatgtagttc agatcggcta
     3421 gcactaggag cagtaagagg gattataaat gctggaggac acttgcccga agaatttggt
     3481 gtgattggat ttgatggggt atttttagac caaatcagtt cacctaaatt gacaacgatc
     3541 aagcaagata ttatacgtat gggtgaagta tgtggagaaa tgttgttaaa aaaaatagaa
     3601 gaaaaagggg cgagtcaagg ttatcgtcgt ttttttcctg aactagttat cagagagaca
     3661 acgaattaag tcttattact atatatatat ttatgaaatt catcgctatt ttcttaaaat
     3721 aatcagcgca ttgctactga aaacaatgaa tctgtgctat tattgagaaa agttccattt
     3781 ttgagaagga tggtttgaat gaaagaaatc agacgaaaac atttccgttt tcctgcgtac
     3841 gatgatgagt taggcgtaaa attaaccaac gacaagaagc gagtattatt tgacggacaa
     3901 gaagatcttt tgactgaaca gaatcagtcc ccgtttgaac agatgaaaga atttcatttc
     3961 acgaacacga acaccgagaa aatccgtcgc aagcgtcgtg caacaaatgg attgaagtca
     4021 gctccgcgta aggaaaattt ggaaaagcat aaaggaaaat taccggatta taccggccat
     4081 taccaatcag aaatcacatc gacaggacga aaaaaacttt ttggtgattc ctctcgttct
     4141 gtcagacaaa gtgaaacaag gacagagtcc aagcatacta cacgaaacgc atctgttgac
     4201 acgaaggtgc gggagcgttc ttattttgtt cctaaatatg tacccgcatc gattatccca
     4261 gaccctagag aaagcaaaat ttctgaggat catttaatcg aatcgatgaa aaaaacggat
     4321 gactcttatc tgttgttcga tacagaaccg acgccgtatc aagaaaaaag aaatggtgag
     4381 ccgtctgtac gaacattcaa tcgaacaaaa acgttagagg aaacaaagca gtcagaagaa
     4441 aaaaaatcga aaaaaagcca tggtatctta gaacgctcat tacaaggatt gatcgatgat
     4501 caaggaaact ctttgggaga aaatagctat tttaaataag tgatatacaa atttatattc
     4561 ggctacagtt ggaaaggaaa cgctgcggcg tttccttatt ttatactcta tccgaaagtt
     4621 tatatcgtat cctcaaattt ttttgagttt aagcgaattt tttctcccaa taagtaagaa
     4681 aataatggca aaataaaaaa acaaactatt ttcgcagatc gtttgcaaaa atagtttatt
     4741 tttttata
//
LOCUS       DADVXK010000147         4739 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.150, whole genome shotgun sequence.
ACCESSION   DADVXK010000147 DADVXK010000000
VERSION     DADVXK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.150"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(402..776)
                     /locus_tag="KB909_002678"
     CDS             complement(402..776)
                     /locus_tag="KB909_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6838638.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            complement(799..2199)
                     /locus_tag="KB909_002679"
     CDS             complement(799..2199)
                     /locus_tag="KB909_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBB6838639.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            complement(2203..2613)
                     /locus_tag="KB909_002680"
     CDS             complement(2203..2613)
                     /locus_tag="KB909_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6838640.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            complement(2631..3122)
                     /locus_tag="KB909_002681"
     CDS             complement(2631..3122)
                     /locus_tag="KB909_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6838641.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            complement(3132..3923)
                     /locus_tag="KB909_002682"
     CDS             complement(3132..3923)
                     /locus_tag="KB909_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6838642.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            complement(3916..4689)
                     /locus_tag="KB909_002683"
     CDS             complement(3916..4689)
                     /locus_tag="KB909_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6838643.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
BASE COUNT         1498 a          974 c          627 g         1640 t
ORIGIN      
        1 gagtgagcat ttttcgaaaa atactaaaaa tttttcaaaa taaaaaaagg catacagaca
       61 ataaactgtc tatacgcctc acagactcta ttctatacat ctaattttgg ctgtcctgca
      121 aaaaatatgt gttagcctcc atcgaaagat caaactttgg aaaacatcat tataactttg
      181 cttggtaaga gctttgctaa aacatgatat gacttgtata caaaatgtgg agtgtattcc
      241 aataaatagg aaggattaca aaatttgaaa ccaaataagt aaaaaatact gtcactttga
      301 attaatttga aatagtaaat tctcattaaa ctattgaaat gctgatacca aaaaatgaag
      361 tacttttcgt tcataccaac ttagagcact tcgttatcta tttatttctt catttggctt
      421 atctctataa tctcatgatt tggtccgtag aaattaaagt aacggattcc attttcccag
      481 aacggtaatt ccataatatt tttatctaat aattcatatc ctaaatcttg aattgaattg
      541 aatacctcat ctatgtcatc cgtatctaat gctagatgat caatggctcc tctacactca
      601 gtagttttat cttcccatat ttctattatc gttccattca actcgaaaaa gccgacttta
      661 cttcccacat tcatttcttc attaatcaga ctaaacccta aggattcata aaagattttt
      721 gaagctccaa aatcttttgt tggaattcca atatgttgta aaccatttaa tttcacttac
      781 atcatccctt caattgtttt aaaatccaca ttcataattt attgaatagt ctagtttatc
      841 taccttgatt gctccctccg taacagtcat acttaatgct gttccgactt tatcatacat
      901 tctagtactt aaagcaacat tatcaatata taaaacagct atcgtatcat caacaattaa
      961 ctttagttca tattctttgc ctatttccaa aaatagtggt cgttgcagcc ccttatcaaa
     1021 catttgaggc caaggatagt tcggagtttt tccgaaagta agctgattat taatcaatga
     1081 aatacgaaat tcgtatcctt cttgagtatc actatctaca aataatttta aagcaaactc
     1141 ctttgttaac gatgtaatag tcaaagttgt ttcaaataga aaataatctt cgattttagg
     1201 aacaattact ctttcttttt ttccaaattc tttctctaac ttaaaacttg aaaatggagt
     1261 gatttcttta aaattctcaa ttattttttc aggcagttta acaccaagag ttttgtctgt
     1321 cttttgaata atttgatgtg gaacaagtgc accgccccaa tcccagttat tttgatcgtt
     1381 ctccccttct tttgttgcca cccagccagt tagaaaacgg ccagtttcat tagttccgac
     1441 tgttcttgct gcataatagg cttttccgtc gaaagcttcg tctactggtg atttccaatc
     1501 tgaaaataat cctgctccga ctcgatattt agtcttttta tcttcacaat actctgaaaa
     1561 aagtaaatac cacgttccat caatttcaaa tatatcaggc atttcaatca tgttaaattc
     1621 attattagcc cagtagtctc ctttgaaatt ccaatctttt aaatcttcgg attcaaaata
     1681 gaccaatctc cccgtcggct ttttcttact tgctggtttt ctagctccta gtatcaaaac
     1741 gtattttcca tgatcttgat caaaaattgc aaaaggatcg cgccaatcat tcttatcata
     1801 tccttcttga ggaacaagtt ttgctgcttc gccatccttt ttccaatgaa ttaaatcttt
     1861 agaacttgca atcattaaca cttctgaagt ttttccatcc aacttagctt tgcgattatg
     1921 tccagtatac aaagctaaat actcattgat tccttggaca atacttccag cgtaaatgta
     1981 ttgatcaatg tcatcgttgc caccacgatg aattacttcc ccgtattctt caaatttcac
     2041 aaaatcagtg gttgtaacta gtgaccaccc aaaaggatca gttaaaggtt taggatttct
     2101 cgtatctcgt tgatgaaata gataaaaagt tccatcttta taaaaaggca tgcaatcccc
     2161 aaaccaaaaa tctttaggct tgtaaaaaat tttttgcatt tatcactcat cctcttcgtt
     2221 agtatgtctt tgcatatctg caagacacgc aattgtattc atatttctta gattttcgat
     2281 gatatcatcg cttttttttc cttgtaatct caaattgaca gcctcaatca aaattcctaa
     2341 attcatgcca ccaagaagtt gaaacccatt ttgaaatact tcacttcttt tagcaaattc
     2401 gttgaaaggt gttccaccaa tcaagtcagc aaataccata acttcttgat tttttacttg
     2461 agaaactatt ttttcaatgt tttcacggaa ttcttcaatg cctgcatctc caagtgttac
     2521 cacatgacaa tttaaattat cgccaaaaaa catttttaat gtatctacaa atccaatggc
     2581 aatatttcca tgagatgtaa ttataaactc catccactca tcctctgttc ttaataaata
     2641 aaatccttta aaaattcttt tgaatctcta ggagtttgta tcactgtcac ttcaactcca
     2701 tcactaatta gttctttaaa agcctctctc tcttcttcag taatatttat cgtcggacgg
     2761 atgcgttctg ttccattcct tcttgataaa tttcctacgt ttacacttgt tattggtaaa
     2821 ccgttatcaa tcaaaaattt aacatcgatt ggagaaactg caacaataag aactttttgt
     2881 ccttcatatt taccagaaag aatattttta actgctactt cccttgtaat tattgaagtt
     2941 ctaacattag gtggtgcagc gaggcgaact acagcttttt ttacgtcatc attggctact
     3001 tcattattaa taaccataat tctgttagca ctcaattgat ttgtccattg tgttgctact
     3061 tgtccatgaa tcattcgatc atcaatacga acatgtataa tacctttcat tttttcatcc
     3121 atattcaaca cctacttcaa aatatttaac gctcttaacg caatagaaac tactaagatt
     3181 aatagaatta cataaactgg tttaaccttt cgtcctaaca aataatacac aattgctact
     3241 acacatgcag gtaataaacc aggcataact tgatcaaaga tttcatttcc ggtcattgtt
     3301 aagtcgcctt gtttaaattc aaagccaaca ttcactttta caactgtggc aatgagtgca
     3361 ccgaccacca ttaaccctaa aattgatact gcatcagtaa tagactttaa ttttgtttca
     3421 atttgagtta gtaggctcgc acccgattct ttcccagcaa ggtataaagg ataagcagta
     3481 atccttaata aaattgatgc cagtatccac aaaataattc caacaaaact accttccaat
     3541 gccatattag ctgcaattgc tccaaaaata gtccatggaa taactacaaa tacactatct
     3601 ccaattcccg ctaaaggacc cattagacct gttttcagag cacttactgc ttccaaagac
     3661 ttattttttt cttctttttc aattccaaca ttcataccaa taatgtaagg cgctgtatac
     3721 ggcgtagtgt taaaaaattg taagtgagct aaaacggatt gtttcattcc ttcaggatca
     3781 tctttatatg tgtccttgat aaaaggaagc atagaatacg cataacccaa cccttccatt
     3841 ttttcataat ttaatgaagt tgcaccattg agaatccacc ggaaaattac ttgtttgtcg
     3901 atttttgtca gtttcttatt catcttcgtc aaaacctcct gttgcagctg gtgctacttg
     3961 agtattattt gatctatttt tatatacgat tagtgcgatt gcagcgccaa gtaacgaaat
     4021 ccctaaaatt ggtatttgga aataaactgc caaaacgaaa ccaactaaca aataggcaaa
     4081 gtaatctttt gtaggtaaat atttaagtag cattcctatc ccaacagcag gtaatagtcc
     4141 ccctgctacc tttaaaccac cggtaaccca ttcaggaata taattgattg cacttcccac
     4201 taacgttggg cctaatatca cagttaacaa aacaggaatt ccagatacaa agcttgtatt
     4261 aattgatgcc aaatattgca tccactctaa tttttgataa tcttcttttt gtgcgaattt
     4321 ttctgccttt tgttgaaaaa aaatgtttgt tgaccacttt agaacatcta gttgtacaat
     4381 taacattgct accggtattg ctaaagttat tcctatagaa gcatcctggt tagttgagat
     4441 tgctaaataa gtaccgatca atgctgctgt ttgataatcc ggtactgatg caccaccaaa
     4501 actagtaata cctagtgtca ttaattgcaa agtcccaccg atataaagtc cagtttgaat
     4561 atctcccata ataagtccgg tcaagaaacc tgcaacgaca ggttgggagg ttccgatttt
     4621 gggcccttcc ttatcccagt taatgaaaaa tccatacaac acaactaaaa atgtttgcca
     4681 aaacgccatt ttgttctctc ctttcttctt atacttttat ataagcaatt actgtgcca
//
LOCUS       DADVXK010000148         4706 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.151, whole genome shotgun sequence.
ACCESSION   DADVXK010000148 DADVXK010000000
VERSION     DADVXK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.151"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1014..1304)
                     /locus_tag="KB909_002684"
     CDS             complement(1014..1304)
                     /locus_tag="KB909_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838644.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="KB909_002685"
     CDS             1706..1942
                     /locus_tag="KB909_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838645.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="KB909_002686"
     CDS             1949..3901
                     /locus_tag="KB909_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6838646.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="KB909_002687"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="KB909_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6838647.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1614 a          818 c          768 g         1506 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagt
//
LOCUS       DADVXK010000149         4701 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.153, whole genome shotgun sequence.
ACCESSION   DADVXK010000149 DADVXK010000000
VERSION     DADVXK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.153"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            76..1581
                     /locus_tag="KB909_002688"
     CDS             76..1581
                     /locus_tag="KB909_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HBB6838648.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
     gene            1878..2969
                     /locus_tag="KB909_002689"
     CDS             1878..2969
                     /locus_tag="KB909_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBB6838649.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(3037..4515)
                     /locus_tag="KB909_002690"
     CDS             complement(3037..4515)
                     /locus_tag="KB909_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBB6838650.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
BASE COUNT         1524 a          695 c          802 g         1680 t
ORIGIN      
        1 ttcctacagc aatttaataa acgtctttaa tatttaagct taataaaaag ataaaacaag
       61 tcaggagttg caaaaatgga aagaactgct cggctcaaaa aaaacactat ttgggctctg
      121 gtgtttcaaa taacttctat tgtctgtggt atgatcttgc tacgtttgat attaacaaag
      181 tacggatccg aggttaatgg aatgattagc tctattaacc aatttctaca aattatttct
      241 tttttacaat taggagtagg cgctgtaatg caatcaactc tatacaaacc actagcagaa
      301 aaggataatt taatgataag tcaaatctta gcttctggag ggaagtttta tcggcaaatt
      361 gcatatattc tactagtata cgtgggtttg ttacttgcag tctattatgt tctcgttcct
      421 aatgaatttg ggagatcata tacaatggca atgattgcaa cattaagtat taattcattt
      481 gctcaatatt attttggtat tgttaatact ttgttattaa gtgctgacca gaaaatttat
      541 attacgtata ttgcacagac aatagcattt atttctaata cagttgcatg tgctttatta
      601 attagtctga acacagagat ccttatggta aaacttatta ctgctataat ttatcttgct
      661 tgtccaatat attatagatg gtatgtggat cgaaactata atataaagag gaatgtgtca
      721 tatgataagg aaccgatccc tcaaaaatgg aatggggttg cacaacacgt agcttctgtt
      781 gtactagata gtactgatgt tgtagtgtta tctatatttt ctaacctgat atatgtatct
      841 atatataatg tgtacaattt agtaatatac ggagtaaaac agctattcat ggctatgaca
      901 aatggcgttc aggccttact aggggaactt tgggtcagaa aagaaataga agttctttac
      961 aaaacatttg catggttcga atggattgta catactttga cagtttttat ttttggctgt
     1021 accggtatac taatcgttcc atttattcaa gtatatacaa gaggagtaac agatgctaat
     1081 tataatcaat tatcattcgc agctttactt gtaactgcta acgcacttca ctgtctgcgt
     1141 acaccttatc atgtaatgat aaaagcagct ggtaaatata aagaaactca aaatagtttt
     1201 ataattgctt ctttgttaaa tttaggttta tcattaattt tggttaaacc actagggcta
     1261 gttggagtag cattaggatc tctaatttca atcacatatc atacactttg gagtgcaaat
     1321 tataattcaa aatatttgct taaatggccg atgaaaaaat tctataaaca gttatttgta
     1381 aacatcttaa ctgtagttct ttcttttggg gcgacatcac aattgaaaat gatgtcaatc
     1441 acatatttgg attggattgt tctcgcaatt aaatgtgcag ttattgtatt tatatgtata
     1501 atcctagtta atgttttatt ttatagaaga tatgtagtaa aaataattag taaaatcatc
     1561 gtaaaaataa agaaaattta atacacaata aatgttttaa taaacttaat aaaattatat
     1621 ttgccaaaat tagacacata tattaaattt tttcttttaa ggttacttat gtgatcaaga
     1681 ataatttcta ttcgttttag aataagttaa tagataatag aaagaagtgg gttgcttagc
     1741 aatttcctat ctgtataatt attctactac gtgcaaagat tagaatgata aaagtgacaa
     1801 tagataagtc taaataagat tttttaatat ataacaaata tgtattcata agaaaaaaag
     1861 aaagtgagtg ctaaaaaatg ctggaattaa acacgtcctt atcaaataga acaatattaa
     1921 taactggcgc agccggtttt attggatcaa atttggttct tgagttatta cgtactcagt
     1981 catcaataaa aatcattggc attgacaata tgaatgatta ctatgatgtc tctattaaga
     2041 actatagatt atcagagata gaaacggagg caaagaacca tccaggatct acttggaatt
     2101 ttatcaaagg ttctattgct gataaagcaa caattgattt catctttgat aattataaac
     2161 caagtatcgt ggtgaattta gcagctcagg caggagtccg ttattcaatt actaatccag
     2221 atatgtatat cgaatctaac ataataggat tctataatat tcttgaagct tgtcgtcatt
     2281 catatgataa tggagaatct ggtgtggaac atttagtgta tgcctcatcg tcttccgttt
     2341 atggtactaa taagaaaatt ccttattcta cagaggataa agtagacaat caagtatcgt
     2401 tgtatgcagc aactaagaaa agtaatgaat caatggcaca tgcatattct aaactttaca
     2461 atattccgtc tacagggtta cgtttcttta cagtatatgg tcctgctggg cgtccagata
     2521 tggcttattt tggttttact gataaacttc gtgctggtga taatatccaa atattcaatt
     2581 atgggaattg caagcgtgac tttacctata tagatgatat tgttgaagga gtaaagaggg
     2641 ttatgcagtg cgctccagag aaaattgatg gggaagatgg gctaccaatc ccaccatatc
     2701 atatttataa tattggtaac aatacgccgg aaaacctact agattttgta gatattctac
     2761 aacaagagct aattgcagca ggggtgctac cagaagatta cgactttgaa tctcataccg
     2821 aactagttcc aatgcaacca ggagatgtgc cagttactta tgcagatact agtgcgttag
     2881 aacgagattt tgaatttaaa ccaagtacaa gtttgcgtga cgggcttcgt aaatttgcgc
     2941 agtggtataa gtctttttat gaagtataat tgtatttttt tacttataaa agtttataga
     3001 aacacctcag acactacaaa tctgaggtgt tattttttaa tctcgttgaa ataaatctct
     3061 ggtatatact ttttctttta catcatcaag attactatcg taacgattag caataatact
     3121 gtgactgata tttttaaaat catctaaatt atttattact tttgaaccaa aaaatgtagt
     3181 gttattttca agtgttggtt cataaattac aatagttgcc ccctttgctt taattcgctt
     3241 cataactcct tgaatagatg actgacggaa gttgtctgaa ttactcttca ttgtaagacg
     3301 gtatacacct atgactacct ctttttcttt ttctgcattc cacgaactgt tagcctcata
     3361 cgtgccagca agttctaaca ctcgatctgc tataaagtct tttcttgtac gattactatc
     3421 gacaattgca cttatcatat tctgaggaac atcgttatag ttagtgagaa gttgttttgt
     3481 atctttcggt aaacaatagc ctccatatcc aaaagatgga ttattataat gtgtgccaat
     3541 tcttggatct aagcaaaccc cgtgaatgat ttcttgtgta tttagtcctt tcatttctgc
     3601 ataagtatcc agctcattga agtaagatac tcgaagtgca aggtaagtat tagcgaataa
     3661 tttaactgct tcagcttctg tgaatcccat gaaaagagtt tcgatatctt ttttgattgc
     3721 tccttcttgg agtaaatctg caaaagtgtg agaggcttct cgtaaagttt tgtcagtttg
     3781 gtccgtgccg acaataattc gcgaaggata tagattgtca tataatgcct tagattctct
     3841 gagaaattct gggctgaata gaatattttt agtattgtat tttttacgaa tactttcggt
     3901 atagcctacg ggtaccgtcg acttgatgac cattattgcc tttggattga cttctaacac
     3961 caatttgatt actgactcta cagcagaagt atcaaaataa ttttgtttac tatcataatt
     4021 tgttggagca gcaatgacaa caaaatcggc ttctctatag gcggctgcac catcagtcgt
     4081 tgcaattaaa ttaagatttt tttcagctag atatttttca atgtaatcgt cttgtattgg
     4141 agatttctta ttgttaattt gttttacttt ttcaggaaga atgtctactg ctgttacctg
     4201 attgtgctgg gcaagaagag tagcaatgga aagacctacg taaccagtac cggctacagc
     4261 aatattcttc gactgatgtt ttgttctgtt tgatttattt gattcattta taaatagatc
     4321 tgttggttca aaatttagaa cttctgctaa tgattctaat tgttgtattg acgggataaa
     4381 atcgagagat tctaatcgac taattaaggc acggttgata ccagtagcta ctgcaagttg
     4441 ttgttgtgtc attttcagag attttctaga atcaataatg atttgagcta aacgtttttg
     4501 agataacttt ttcatgatgc actccttttt ttgttgctaa taataacaaa caattttttc
     4561 ttctataaca gaatagctta ttattaataa aactgtcaat ttttttattg attaaaaaga
     4621 tattttttga ttttaagtat tttcaattat ttttttgtta tttaaagtaa ctttatagat
     4681 tgtgaataac tttatacata a
//
LOCUS       DADVXK010000150         4620 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.155, whole genome shotgun sequence.
ACCESSION   DADVXK010000150 DADVXK010000000
VERSION     DADVXK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.155"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            153..959
                     /locus_tag="KB909_002691"
     CDS             153..959
                     /locus_tag="KB909_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBB6838651.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            977..1684
                     /locus_tag="KB909_002692"
     CDS             977..1684
                     /locus_tag="KB909_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBB6838652.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1681..2652
                     /locus_tag="KB909_002693"
     CDS             1681..2652
                     /locus_tag="KB909_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBB6838653.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2645..3673
                     /gene="vanB"
                     /locus_tag="KB909_002694"
     CDS             2645..3673
                     /gene="vanB"
                     /locus_tag="KB909_002694"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBB6838654.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3679..4287
                     /locus_tag="KB909_002695"
     CDS             3679..4287
                     /locus_tag="KB909_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBB6838655.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4353..4526)
                     /locus_tag="KB909_002696"
     CDS             complement(4353..4526)
                     /locus_tag="KB909_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838656.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1300 a          972 c         1230 g         1118 t
ORIGIN      
        1 attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga aaactacaga
       61 ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca gccacaaatc
      121 gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat cattccaatg
      181 cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt ctatgtgcgt
      241 tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct tccgtattgg
      301 aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact gacgtagtgg
      361 agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa caggaatgga
      421 gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg gagcttgagc
      481 aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa gatttgtttg
      541 atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga acaacagaaa
      601 aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc tacacctctg
      661 cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc gagcatcagc
      721 ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac gaggtttata
      781 gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca ccagacaaga
      841 cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc atcgaagctg
      901 ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca gaaaaatgag
      961 aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt tcctgcttcc
     1021 aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg acggctgtcg
     1081 ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa cggattgcgc
     1141 attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg tgttcaactt
     1201 aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa ccttttcttt
     1261 ctggttgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg aagtaaagga
     1321 gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt cagagggctg
     1381 gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatggg tgaccttaga
     1441 tgatgagaaa atcatcggtc aggtgttcgc cgacaaagag ccccaagcat tatacaaaat
     1501 tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat atgcccaggt
     1561 taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc tgctttatac
     1621 aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagg aggagaacca
     1681 atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc aaatgctttc
     1741 cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc gatatcggca
     1801 gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taagccataa gtccgaggtt
     1861 tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc tacccgcagc
     1921 atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc ggttggcacg
     1981 gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct gatggccata
     2041 cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt ggatcgtatc
     2101 cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca tatcgggcaa
     2161 gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga taacagccga
     2221 aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga tattgttacg
     2281 ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca aattggagag
     2341 atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga taccggggcg
     2401 ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt gttggagggc
     2461 gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc ctttttgtcg
     2521 cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta cactgagcgt
     2581 gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga aaggagttta
     2641 cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg aacatgatgt
     2701 gtcggtaaaa gccgcaatag aaattgctgc gaacattgat acggaaaaat tcgatccgca
     2761 ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat gtacggaatg
     2821 ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg ggctgcttgt
     2881 catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg ttttgcatgg
     2941 caaatgcggg gaggatggtg cgatacaggg gctgtttgta ttgtctggta tcccctatgt
     3001 gggctgtgat attcaaagct ccgcagcttg catggacaaa tcactggcct acattcttac
     3061 aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt gataaaggtg acaagccgga
     3121 ggcgggtgcg cttacctacc ctgtctttgt gaagccggca cggtcaggtt cgtcctttgg
     3181 cgtaaccaaa gtaaacggta cggaagaact taacgctgcg atagaagcgg caggacaata
     3241 tgatggaaaa atcttaattg agcaagcgat ttcgggctgt gaggtcgggt gtgcggtcat
     3301 ggggaacgag gatgatttga ttgtcggcga agtggatcaa atccggctga gccacggtat
     3361 cttccgcatc catcaggaaa acgagccgga aaaaggctca gaaaatgcga tgattacagt
     3421 tcccgcagac attccggtcg aggaacgaaa tcgggtgcag gaaacggcaa agaaagtata
     3481 tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt tttttgcagg aggatggcgg
     3541 catcgttcta aatgaggtca ataccctgcc cggttttaca tcgtacagcc gctacccacg
     3601 tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt gacagcctga ttacattggc
     3661 gttaaagagg tgataagtat ggaaaatggt tttttgtttt tagatgaaat gttgcatggc
     3721 gtccgttggg atgccaagta cgccacatgg gataacttca caggaaaacc ggtggatggg
     3781 tatgaggtga atcgcatcat cggcacaaag gccgtggcgt ttgctctgcg cgaggcacaa
     3841 atccatgcgg ctgcgcttgg ctatggcttg cttttatggg atggatatcg gccaagaact
     3901 gcggtggact gcttcctgcg ttgggcagcg caaccggagg acaatctcac aaaagaaaaa
     3961 ttttacccca atatagagcg agccgagttg attacaaagg gttatgtggc ctcacaatcc
     4021 agccatagcc gtggaagcgc aattgatctt acgctctacc acctggatac aggggaactt
     4081 gtttcaatgg gaagtaactt cgattttatg gacgaacggt cgcatcatac agcaaaaggg
     4141 ataggggatg cagaggcaca aaatcgaaga tgcttgcgta aaatcatgga aagcagcgga
     4201 tttcagtctt atcgctttga atggtggcac tataagttga ttgatgagcc ataccccgat
     4261 acctatttta attttgccgt ttcataatga aagtattggt tttgtatcag attttggatt
     4321 tgataaaatc tatgctggtc atggacaatc ttttactgga aagtggttaa agcatctttt
     4381 gtaatacatt gcaaattata gtattcaatc tgcccagcgg cagaaaagaa aaaaaccgct
     4441 gttgggcaga cctttcccac gcccattttg tattttgctg gcggcggttt tgagaaatca
     4501 aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc cataggagga tgccgctatg
     4561 ctgttttgct attgccatgc tctaatccac ttccaccact caaaaaaagc cttgcccctc
//
LOCUS       DADVXK010000151         4590 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.156, whole genome shotgun sequence.
ACCESSION   DADVXK010000151 DADVXK010000000
VERSION     DADVXK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.156"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            186..2855
                     /locus_tag="KB909_002697"
     CDS             186..2855
                     /locus_tag="KB909_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBB6838657.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="KB909_002698"
     CDS             complement(2946..3566)
                     /locus_tag="KB909_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6838658.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="KB909_002699"
     CDS             3680..4219
                     /locus_tag="KB909_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838659.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="KB909_002700"
     CDS             4216..4554
                     /locus_tag="KB909_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBB6838660.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1420 a          790 c          860 g         1520 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt
//
LOCUS       DADVXK010000152         4462 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.157, whole genome shotgun sequence.
ACCESSION   DADVXK010000152 DADVXK010000000
VERSION     DADVXK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.157"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(52..522)
                     /locus_tag="KB909_002701"
     CDS             complement(52..522)
                     /locus_tag="KB909_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBB6838661.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="KB909_002702"
     CDS             complement(681..1139)
                     /locus_tag="KB909_002702"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBB6838662.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="KB909_002703"
     CDS             complement(1310..2455)
                     /locus_tag="KB909_002703"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBB6838663.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="KB909_002704"
     CDS             complement(2468..3385)
                     /locus_tag="KB909_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBB6838664.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="KB909_002705"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="KB909_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBB6838665.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1374 a          830 c          849 g         1409 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt tt
//
LOCUS       DADVXK010000153         4319 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.158, whole genome shotgun sequence.
ACCESSION   DADVXK010000153 DADVXK010000000
VERSION     DADVXK010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.158"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            4..1293
                     /locus_tag="KB909_002706"
     CDS             4..1293
                     /locus_tag="KB909_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6838666.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            1312..1719
                     /locus_tag="KB909_002707"
     CDS             1312..1719
                     /locus_tag="KB909_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6838667.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            1742..2611
                     /locus_tag="KB909_002708"
     CDS             1742..2611
                     /locus_tag="KB909_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBB6838668.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            2613..3233
                     /locus_tag="KB909_002709"
     CDS             2613..3233
                     /locus_tag="KB909_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6838669.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            3683..4288
                     /locus_tag="KB909_002710"
     CDS             3683..4288
                     /locus_tag="KB909_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6838670.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
BASE COUNT         1431 a          738 c          940 g         1210 t
ORIGIN      
        1 aacatgggcg ttatcaattt tatcatcgaa aatattttga ctcaggcatc gatcaccatt
       61 gcattgattg ctatgttggg tctactactg cagaagaaat cagcaggaca agtcatctct
      121 ggcacgttaa agacactcct aggatttcaa gtgttgagtg ccggttcgag catcatcgtt
      181 ggaagtttaa cttatttcgg gaaaatcttt actgaaggat ttcatatgca agggatcatc
      241 ccttctattg aatctatcaa tggtcaagca atgaatgatt tgggtttagg tagagatatt
      301 gcactgacgt tcttagccat ttttgtattc aatattattt tggctcgttt cacaaaatgg
      361 aagtacattt ttttaactgg tcaagcaatt ttatggatgg caacgatgac gacagtcttt
      421 ggctattttg ccggtctgcg agggatcgta ttgatcttgg tcggtggttt tatcggagct
      481 tgtttcgcca ttgctatgcc ggcagtagcg caaccgatca ttcgtaaaat cactggatca
      541 aatgatattg ctttaggtca tttttgtacg atcgggtact tatttgaagc cggtgttgct
      601 aagctttttg gtgagaaagg cgaaaataaa aagtcgatcg aagatatcaa gttgccgaca
      661 catttcgaat ttctgcaaga tacttatttg tctgtcatgg tcgtgatggt cccgctatat
      721 atcatcactg ttttatttgc aggcgaacca ttcgcttctg aattatcagg agatcaaaac
      781 tatatcatgt ttgccttttt acaagccatc caattcgtag tgggtgtgta tgtattgcta
      841 gctggtgtac gtctactgtt aggtgaaatc gtgccggcat ttcgagggat agctatgaaa
      901 ttagttcctg atgcgatccc tgccttagat tgtccagttt tctttcctta tagcccaaat
      961 gctgtcattt taggtttcat tacgacaacg attggtacga ttattgccat gtttactttg
     1021 cccatgttcg gcttagcgat gattttacct ggtatgctaa ccaatttctt tgccggaggg
     1081 acagcaggga tatttggcaa cgcagttggc ggacgccgag gagcgatcat tggcggtatt
     1141 gctcatggtt tctttattac attattgccc gctttgctag taacgatctt taattcgatg
     1201 ggattcaaca atgctacagc aaccgatgta gatacagtag ccgcagcact cttatatgcc
     1261 tggatcttaa gcccagtttt gaaagcattt taattgaaag tagggaaaat gatgtttgga
     1321 ttttttaaga aaaaagaaaa agaaccgaaa aaagttctgg caaaagaaga aaaagcccta
     1381 tcgccagaag cgaccgaaaa gattcaatca gagattacac aattgaaaca agagatttcc
     1441 actacccaag ataagcataa attagcgaaa ctttatgaac aagttggact taaattttct
     1501 gaattgtatg tgaacgatca agccatccaa tatttagaaa agagtttgga aaataaacag
     1561 acgatcggag atgggtataa aaaactgatg agcctctata accagaagcg tgcagatgct
     1621 gctcgtgctg gtgatgatca agggatcgat tactacatgg gcaaaatgga tgagatgcga
     1681 caaattgcaa aacaagtaac gatcaaagga aacaaataaa aagataaggt ggcaataaaa
     1741 gatgtataca acattgaaag aagtaacaaa aacagcagaa gagttgaatt ttacagttgg
     1801 agcttttaat acgcataacc tagaaatgct tcctgctatg ctaggcgcag caaaagaaat
     1861 gggttcgccg atcattattc aaacaagtgt cgataccgct aaatatatcg gcatgcatgt
     1921 gttagtcaat gtaatgacag ctattgcaga agaagaaatg gttgatgcag tcttgcactt
     1981 agaccacgcc cgagactttg atgatatcaa agaagcaatc gacagcggat atacttctgt
     2041 catgtatgat gggtcccatc tgcctttcaa agaaaatatc ctgaagacaa aagcagtagt
     2101 agaatatgcc catgcgcacg gtgtttccgt agaaggagaa cttggaacaa tcggcggtac
     2161 agaagaagga atccatgtcg ctgaaaatga caaggtatat acaagaccgg aagacgcagt
     2221 gaaatttgta gaagctacag gcgtggatgc attagctatt gctatcggta cgaatcatgg
     2281 acaattcaaa tcaaaaacag aagtaaacat tcccttgctg aaagaaatcg atgcagtagt
     2341 tgatgtcccc ctagttatcc atggaggaac aggtgtgaaa gaagaagatt atcctgaatt
     2401 gatcaataac gggatccgca aattcaatgt tggaacggag cttttagtca actggacgaa
     2461 agtagctaaa gaaaccttta gtgaaacaga aatcaacaag tctcttcgcc ataatgtgat
     2521 tccagcaaat gaagcagtaa aagaaattgt caagcataag attggactgt ttatgaactt
     2581 ggaaagtcca attaacttag gaaataaatg agatgaaaaa gtatttcatt cttctggctg
     2641 gtagtcctgg tacaggaaaa acatatctta tgaataaact acgggaacga tttccagata
     2701 tgtatgccat cacgctcgat gaaatcaagg aatactatgc agaatccatc gggtttaaca
     2761 atttggaaga acgggcggaa caagaaagga cgaaagttta tcctttctat tacaaagcac
     2821 ttgatttgta tatggaagca ggaaagaaag tgattgtgtc cgagtatcct tttagtgata
     2881 agcaaaaagc acgactccaa gaattagcag atagatacgg atatcaggtg atcacgattc
     2941 gcctaacagc agactttgaa gtgttatggc aacgtcggta caaacgtgat cgtgaatcag
     3001 atcgtcattt gagctatatc atggatcatt atcactatgg tgacgtattg gaagatcgaa
     3061 cgaaagggac caatcatatt acgaaagaag cattcaaaaa gatcatcgcc gaccgaaaat
     3121 atgacaaatt ccagttagga acactatatg aatttgatgt aacagactat actcaagtgg
     3181 attacactcc actattggat aaattagaaa aagaaatcaa tgacaataag taacaaagaa
     3241 atggcttaat atcgaaaaat tggcttttga acgctgttta ccgagaggtc gtgagcctgt
     3301 cgttcagctc cgagtcacaa ggagcaattt caaaaaaaca gcttctcatg tttgatgaat
     3361 attgtgactt gtgaccgagg agttggtagg agaacaccgt ttagtgggga ggttgtgaaa
     3421 aagctgtcct gcctcaatta ataagaacag ccagacaaga atagctcgtc atatttttcg
     3481 tttggtgggg cttattaccg cagatgcaag cttttgaacg ccatttattc acagccccag
     3541 agaagtcgaa tgtcttttgt tctcgagttt tttaacattc ttttatttat tgcagatttc
     3601 attatattta tttgccgtaa ttaaaccagt cttctatact tgattacata gtcatacatt
     3661 tgctaaaaaa gaagggaaga gaatgaacaa gaagttggct caatacaaaa gactactcgc
     3721 actttctcaa gctggtctat attatggaaa agatgtattt gataaagagc gttttgagga
     3781 gatccggacg atttcattgg aactgatcag tgaaatagga aaagaaactt tcgaagaaat
     3841 aaaagcgctc acaacgattg gagaaggaca tccaacacca aaagtagatg ttcgtgccta
     3901 tatcaaaaaa gatggcaagg tcctactaat cgaagataaa cggacgaaag aatggtcact
     3961 tcctggtgga tttgctgaaa taggattgtc tcctgaagaa aatgtgcgta aagaagtcta
     4021 tgaagaaaca ggattaacag tagaaactac tcagttgcga gcagtttttg atacgaataa
     4081 acaaaaagat attccacagc tttttcagta ttataaactt gtttttgctt gtgcgatcca
     4141 cggtgaagag gccaagttta ttgagaataa tgaaacttcc aacatgggat tttttagtat
     4201 agaagagttg ccaaagctat cagaaaagcg aacaacgaag aaacagttac ttattttaga
     4261 aaacaaaaac cagatctatt gtgattgagc tttttcgtaa aagaagaaaa gaatatact
//
LOCUS       DADVXK010000154         4311 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.159, whole genome shotgun sequence.
ACCESSION   DADVXK010000154 DADVXK010000000
VERSION     DADVXK010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.159"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(107..1873)
                     /locus_tag="KB909_002711"
     CDS             complement(107..1873)
                     /locus_tag="KB909_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838671.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1833..3587)
                     /locus_tag="KB909_002712"
     CDS             complement(1833..3587)
                     /locus_tag="KB909_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838672.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3697..4266)
                     /locus_tag="KB909_002713"
     CDS             complement(3697..4266)
                     /locus_tag="KB909_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBB6838673.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
BASE COUNT         1455 a          814 c          601 g         1441 t
ORIGIN      
        1 ttctttcgtg tattcaaaat tagatgctgt ttaataaaat tattcttttt gaaaaagaat
       61 tataactata tcccaaaaat tgtaggttaa tttaaagcct atttcatcat cgtgattgag
      121 cttctttttc atagacgaat ttctcagata gtttagtttt ctttatgaga tttttgtata
      181 tttctgacct tcgatacaac tcattatgag taccttgatc aactagtttt ccttgatcca
      241 tcactacaat tttatttacc ttttcaatag acttcaagcg atgcgatata attagtactg
      301 tcttatcttg tattaaacga tttaaacttt cctgaatacg tttttcattt tccgcatcta
      361 aactggcagt aatttcatct aaaattaaaa ttggcgcatt tttcaaaaaa gcccgtgcta
      421 tggataggcg ttgtcgctct cctccagaaa gtgaacttcc gttttctccg accaatgtat
      481 gataaccgtc aggtagtttt tcaataaagt cttcgcagtt agctaaacga gctgcttttt
      541 tcacttcctc atctgacgct tgactatttc caatacgtat attttccaaa atacttgtat
      601 taaacaaagt tacctcttga aaaacaatag cgattttgct aaacaaagaa gctggagata
      661 cacgtttaat atcataccca tcaattaaaa tacagccttc atcataatca tacagtctag
      721 acactaattt caagatacta gttttcccgg aaccactagc acctactaac gcagtcactt
      781 ctccttgttt agccgtaaaa gagatatgat ctaaaattgg ggtattgtta tcatatgaga
      841 aagagacatc tcgcaactca atgtcaaaag atttcagagg actatctgat ccctcttgga
      901 tactggtttc cttcatagct ctaattcgct gtattttagg agctaaataa aatatttcaa
      961 gcactgcttc tttcatagaa tcgaaggaat cctttatttt tattgcggct agtaagtaac
     1021 caacgacgta gagtatagtc acttcacccg ttaacagtaa gtgaacacct actagaatga
     1081 ctactgctaa actaacatat gagaaaatag aggataaggc catgactgaa aaagtactta
     1141 attctacctt taaatgaatc ctttcactct cttccatttt tttgaaaagt ctgtcttgaa
     1201 cttttttaga tagattaaag ctattaatct cttgctgcaa ttctatagtt tcttgaaatt
     1261 cttccgagtt ctctctcaaa gtatcgtaat atttagtatt ggctttcgtt tgggatttct
     1321 ttgataacaa gattaagaca aaactaaata acgttggcaa aataacagct aatcccattt
     1381 tgacattacc aaccaaaagc atcactgaaa taaaagggaa aaacagagcc ataccgccgg
     1441 ctttaggtat tgcatgactc atcgcatgct caataccttc aacgtcagac atgatagttt
     1501 gagataaatc tgataaatta tgttttgaaa aataggataa tggtaaattt gacaaatcgt
     1561 ctgcaatttg cactcttaaa tgcgcacttt ctttataagt actattatat aagttttcat
     1621 actccctatc taacaaccaa tacatgaaaa gcaaagtaac aaacgatacg gcaaaataaa
     1681 gccaacgggg ctttgtattt tctaaaacta attcgtctat cagcatcatt ataatgaatg
     1741 ctggtaccat attaatgcag tatacaaaaa aactagaaat agaagcttta gttaaagctt
     1801 ctgcgccctg atcacttaaa gcaaatttgt ttttataaaa acttttcatt gtcaagcctc
     1861 caatcatttg cattctcata attagtgacc aattgtttat acacttgatg tttagccatt
     1921 aattcattat gatttccacg ttctactatt ttcccttctg acaagacaag aatttcatct
     1981 acagatttaa tgctggataa tcgatgagct atcataataa ctgttttttc tttcatcaga
     2041 tgttgaaaag ccttttgtag ttcatactca ttatctggat caatagatgc actggcttca
     2101 tccataataa caatctttgc atcttttaaa attgctctgg caatagctat acgttgtttt
     2161 tctcctcctg acagataaac tcctttacta ccaattaagg tatgctctct ttcgggaaat
     2221 ttttctaaaa tcgattcgca accggctaat cttagcgcgt caaatacttt acttgctggc
     2281 gcttgaggat ttgctataga aacgttatcg taaatactct gattgaatag tttcgtatct
     2341 tgaaagacaa aagcaattgt gttaataatt gtgtcttttg aatagtgatt taaaggctta
     2401 ccaccaattt taatctgtcc cttatccaca ttgtagaaac ctgaaattag tttagctatc
     2461 gtactctttc cgcttcctga ttttcctact aatgcataaa ttcttttttg ttctaaaact
     2521 aagttgaaat tttctaaaac acactcttct ttgtatgaaa agctgacatt ttcaaatgca
     2581 atgtcacaat ttttaatctg tgtctcgttc ccatatttta gttggtcttg cttcatttct
     2641 aaataaaggg agtctagtgt ttcgactgca tatcttgctt caaacaagtg catacttaca
     2701 tacattattc tcatgaaaga aacaaaaata attccactta aaaaaaacaa catcaacaag
     2761 tcaacagcta atatcttggg agtggtaaga gaagttataa aaaaggttat aggaactatc
     2821 aaaatgcaaa ctatgccaaa aaatagccat tgaaaaagaa caaaaggtgt tttcccactc
     2881 aaagaatact tatatgcaaa cttagcataa tcgttaattg ctttattcaa ggctttaaat
     2941 gatgttactt tagcaccaaa tatctttata acttgaattc cgcggatata ttctaccgtt
     3001 tcagagctta acacatctaa cgattcttga tatttttgaa taaaatttgt attctctgtc
     3061 attttcttta acaagaatac accaattact aacatggcga ttagaaccaa tccaatttta
     3121 aagttaatga aaaagcctaa ggcaactgat aaaacaggtg ttactatggc ttgagcacta
     3181 tctggaatca agtgagcaat tgccatatgt gttttagccg cgttgtcatc aattgtcttt
     3241 cgaatatatc ccgaagaatt taaatcaaaa aaacgaaaac ttgcttctgt taaaccgcta
     3301 attccctttt ttctcaaatt agtctctaag cgaaacccaa ggatatgaga aaataagcca
     3361 gaaaaaatat aaaataaagc tcctaaagtt aaccaagcaa cagtttgaac cgcataactc
     3421 ttagctaaat attcatctcc tacaataatt agagactgaa gaaatttgta aatactgtaa
     3481 tatccataga ctgttaatac gacagaaaaa tcagaaaata aagtggctaa ccatccgtag
     3541 tatttcattt tagggacata actaaataat tttttgtata ctttcatttt ttcctccccc
     3601 gcattcaatt tcttctctta ttcgtttaca actgttaatg ctttccgtaa tagcgtaaat
     3661 tagagatgta caaacagata aaaggtaaac tacgttctat tttttgtatt tttttaagac
     3721 ttttcttcca atcaatacac caatcataga taaacttgct acaactaaca ctgaaatgat
     3781 tccccatata cctaccgcat agtggatcat tgcatccatt gttgcagcag attgtccttt
     3841 atctatccaa tcttgacgaa aacgatctgt aaagaaccat ataggaatcc actgtccggc
     3901 agcactgcct aattgcatta gagcccaaga cgcaacttga ggaattgctc gatcatatcc
     3961 aaatacagat agaataatat cagctaagat cgccatacta atcgaactga taaaccaagg
     4021 taagtacgcc ccgcccatta acgtaaaaaa taacaataaa acaattgtgt aaatagtaaa
     4081 aattcctttt ctagggtagt tatagctaat ataaacaaat atgattccag ataataatcc
     4141 aaaaatcccg ggggatatgc tgtgaccaaa cgccccacca atactactaa ccattattga
     4201 aaaaaagtaa attactaggg aaataactgt agctaaacca ataaaaatat aatcttttgt
     4261 tttcatatat attctcctca attctatttc gttatgtcat taaaaatctg t
//
LOCUS       DADVXK010000155         4169 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.160, whole genome shotgun sequence.
ACCESSION   DADVXK010000155 DADVXK010000000
VERSION     DADVXK010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.160"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            75..503
                     /locus_tag="KB909_002714"
     CDS             75..503
                     /locus_tag="KB909_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6838674.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="KB909_002715"
     CDS             490..732
                     /locus_tag="KB909_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838675.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="KB909_002716"
     CDS             complement(1032..1247)
                     /locus_tag="KB909_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838676.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="KB909_002717"
     CDS             1354..1668
                     /locus_tag="KB909_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838677.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="KB909_002718"
     CDS             1772..2950
                     /locus_tag="KB909_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6838678.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            3353..3646
                     /locus_tag="KB909_002719"
     CDS             3353..3646
                     /locus_tag="KB909_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBB6838679.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1419 a          624 c          814 g         1312 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttt
//
LOCUS       DADVXK010000156         4092 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.161, whole genome shotgun sequence.
ACCESSION   DADVXK010000156 DADVXK010000000
VERSION     DADVXK010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.161"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(202..1707)
                     /locus_tag="KB909_002720"
     CDS             complement(202..1707)
                     /locus_tag="KB909_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6838680.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1704..2390)
                     /locus_tag="KB909_002721"
     CDS             complement(1704..2390)
                     /locus_tag="KB909_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838681.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2583..4004)
                     /gene="gndA"
                     /locus_tag="KB909_002722"
     CDS             complement(2583..4004)
                     /gene="gndA"
                     /locus_tag="KB909_002722"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBB6838682.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1127 a          861 c          696 g         1408 t
ORIGIN      
        1 tttattattt ttaaacacga atattacagc attttattgt tttttcgttc atctaaaaga
       61 tacttacatt taattaacgg atgttattct atttaattgt tcgctagttt ttttataatg
      121 acatccctga atttctcact tgcttgtatt ttgtacctta ttctttgttg gatatataaa
      181 aaaacaagta aagcacatgc tttacttgtc ttctgccttt gcgataggaa taaagattct
      241 aaaaattgtc ccttgcccta ctacactttc tgctaagata cgtcctttat agttttcaac
      301 cagttgttta gcgatagaca accccagacc atttccaccc ttcgttctag ctcttgcttt
      361 atccactcga taaaaacgat tgaagatctt attaaggtct tctttgggta ttccttcgcc
      421 aaagtcctga atcgcgatct caaattcatt cagagtggaa gaaatagaga tatggacttc
      481 ttttcgtgta gttgaatact ttactgcgtt atccaatatg ataatgatta attgttcaaa
      541 gtgattacga taaatttgca gggtcacttc ttttgtcaaa tcatcatcta aagtgatcac
      601 atagtctgga tataatatct tgaaattatt ataaacttga taggtgactt cttttccttt
      661 agttgtttca ttcgcataat gaacatctac ttgttctgct cttgataagt ctagcatctc
      721 ttgaactaag cttttcatac ggctgatttc ttgcatgctg gcgcttaatg attcttctaa
      781 tatctcagga tcatctttcc cccaacgatt tagcagacta agatgccctt caataattgc
      841 aacaggtgtc cttaactcat gagatacgtc ttccacgaat tgctcttgtt gttcaatata
      901 caaacgcata cggtcaagca tctcattgaa tatttcagct aaatctgcca attcatcatt
      961 tgtgtcgatt tcaggcatgt ggatatctga ttgcggatct ttacgtatag tatccattgt
     1021 atctctgagt accttgagtg gttttaagaa ataagaagat aaaaagaaac ctaaaatact
     1081 acttaagatc aaagaaacaa cttctaaaac aataagagtc aataatagct tatttcgaat
     1141 atcatagaaa gaagataatt catagaagct ttgcgcatag ccgatctttt ctcttgtacc
     1201 tttagaatat ataggctgga tagataaaaa gccagttttt ccttctagtg taacgatcgt
     1261 tggaacttta cgtgtagtct gaatcaggtt tcgactgttt tcatgggttt taaaaatcaa
     1321 gttctcgtcc aaatcataaa cataaagatc cattgatggc tgccctagct cagctataaa
     1381 gggatcgatc ttcattaagt ttccttcgac cagtgaagta tgatctacga cctcatctcc
     1441 gtcatttgtc gctttcgtca gattacgata cgtatttact aatgtcagtt cttcatccga
     1501 gttagccaaa cgagaagcta cttctgaaat cgtacgctct acattgtttc tttcttttgc
     1561 cacaatcaga ttgatagatg atttataggt aatgacagcg aaaattgtaa acacaacgaa
     1621 tatgaagaaa gaactcgcaa aggcccactt gattgtcaag gagggccctt tcagttctct
     1681 tttttccgat tttttcggct ttatcacgag cgcatcacat aacctgttcc gcgtacagtt
     1741 tggatatagc tttcctcccc gggaacgtca attttgttgc gaagataacg aatatatacg
     1801 tccactacgt ttgtttcaac ttctgtttcg tatccccaca ctttatttag taaaacgtca
     1861 cgtgctaata ccacgttcac gttttccatt aaagtaagca gcaactcgta ttctcttttt
     1921 gttagttcaa ttacttcatt tccgcgacgt acgacacggt tttctttttc gatagtcaaa
     1981 tcgcgataag taatagtagt ttgtttagcc acatttttat cgccttcaat atcgattcga
     2041 cgcaacaatg cacgaagacg tgctaataat tcttcgatag caaatggttt gacgatgtag
     2101 tcatctgctc cgtggtcaag tccagataca cgatcgatca cagaatctct tgcagtcatc
     2161 ataatgattg gtgtattttt gacttggcgt acacgtctgc agacttctaa accgttcaat
     2221 tctgggagca tcagatccaa caatatggca tcccactcat tatttaatgc cgcatctaaa
     2281 ccagttcggc cgttgtagtg gacttctgcg ttataccctt catgcttcaa ctctagctcg
     2341 acaaatcgtg ccaagttctt ttcatcttca atgattagaa tattgctcat ttattatttt
     2401 atcctttcta ttctactggc tttttaaaaa ctctatcatt ataccgataa tatgcttaaa
     2461 aatctatagt cattttatca tggatagcaa ttttaaaaaa gagctgaagt ctactcataa
     2521 caatcgactt cagctctttc gtcctctttt tattttctca tttcctaaca gccgaaagac
     2581 tattattctt catggtacca tgagtaatgg aagattcctt ctttgtcgac acgctcatag
     2641 gtatgtgcgc caaagtaatc gcgttgggct tggattatat ttgcaggcag acgttctgct
     2701 ctgtatgaat cgaagtaagc gatggctgat gagaaagtcg gtacaggtac gccagcttgg
     2761 acagccaagg caacgacgtc tctgactgat tgctgatatt ttttcgtgat ttcaacgaag
     2821 taatcatcta gcaataaatt ttcgatctca ggatttttgt cataggcatc cgtaattttt
     2881 tgcaagaatc gagctcggat gatacatcca gcgcgccaga tttttgcgat ttcaccaaat
     2941 ggcaagtccc aatcaaattc ttttgaagcg acacgtaatt gagcaaatcc ttgggcataa
     3001 ctcatgattt tactgaaata caacgcttct cggatttttt cgaccaattc ttttttgtct
     3061 cccgtgaact caaaatcgtt cgtacgagac aaaatcttgc ttgcttgtac gcgttcttct
     3121 ttataagcag aaatatagcg ggcaaataca gattcagtga tcaatggaag tggcacacct
     3181 aagtcaagcg cgctttggct tgtccattta cctgttcctt tattcccagc tgcatcaagg
     3241 atcacatcta ctactggttt acctgttcct tcatcgtctt tacgtgtcag aatgtcagca
     3301 gtgatttcta tcaaatagct gtctaattcg ccttgattcc attctttaaa gatatcagcc
     3361 atttcttcta ctgaaaggtt taaaatattc ttcattaagt cataagattc agcaatcagt
     3421 tgcatatctc catactcaat accgttgtgt accattttca cataatgtcc ggctccattt
     3481 gggccaatat atgtgacaca tggtgctccg tcttctgctt ttgcagaaat ttgctctaag
     3541 attggtgcaa ctagcgcata ggcttctttt tgtccaccag gcatgattga aggtcctttt
     3601 aaagctcctt cttcaccacc ggaaacgcct gtaccgataa agttgatgcc agagttggct
     3661 aactcttcat tacgacgcat cgtatcttta aagaatgtat ttcctccgtc aatcaaaata
     3721 tcgcctttat caaggtgagg aagtaactct tggattgttg catctgttgc cggtcctgct
     3781 ttgaccatta gcaagatccg acgtggtttc tcgatagatt ctacaaattc ttcgattgta
     3841 tatgttgctt tgaaattttt atctgggtgt tcttctacta cagcggttgt tttagcccct
     3901 gtacgattga ataaagccac tgaatagccg cggctttcta tgttcaaggc tagattttta
     3961 cccataacgg ccataccgac aacgccgatt tgttgttttg acatatgaac tcctcctaca
     4021 tacgggattt ctccctaatc tcttacatta tagcttaaca cggctacatt gcaaactaaa
     4081 gaacaacata tt
//
LOCUS       DADVXK010000157         3904 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.162, whole genome shotgun sequence.
ACCESSION   DADVXK010000157 DADVXK010000000
VERSION     DADVXK010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.162"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(103..1374)
                     /locus_tag="KB909_002723"
     CDS             complement(103..1374)
                     /locus_tag="KB909_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6838683.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            complement(1658..2605)
                     /locus_tag="KB909_002724"
                     /pseudo
     CDS             complement(1658..2605)
                     /locus_tag="KB909_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            2617..3090
                     /locus_tag="KB909_002725"
     CDS             2617..3090
                     /locus_tag="KB909_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838684.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            complement(3263..3817)
                     /locus_tag="KB909_002726"
     CDS             complement(3263..3817)
                     /locus_tag="KB909_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838685.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
BASE COUNT         1255 a          714 c          593 g         1342 t
ORIGIN      
        1 ctaattctag tgaatttgcg acgaggaact gctagatcac agttcattct ctctatcgtt
       61 cggatatttt attgttaact atacttattt cacagagctt ttttatttga ttttgtgaac
      121 agagtctcga gaaatcaatt ctccctctaa tagtagtact tgatttttta tttcttcttg
      181 tttggccagt ccaatcagtt ggtgaaaagc aatcgccccc ttgttacctg gatttagtcg
      241 tattgttgtc aacgcaggat ccattaattc tgcaaaagta atatcatcaa atccaataat
      301 cgataattgt tccatcactc gtttattctt attttttaaa aattttacta atttagccgc
      361 taaataatct ccagtaacaa caattgcagt aaattcagct aattcttgat aaattcgctc
      421 aaattcagag ttgttatata tccaatgcga tttaaaggtt aaatgatatt tctttaatgt
      481 atcgatataa gcttgatgtc gttcttgaat aacacttggt tcacctacaa tgtagtcaaa
      541 agaaagaaac gctattttct catgaccata atgaatcaaa tgttccactg ccaatgtact
      601 agcttggtaa tcatttgtat ttacaaataa acgattcatt tgttgttcaa gttctcttaa
      661 tgtctctttt gaaagatgcg tatcaatata aacaacagga ccatcaaaaa cgttatttaa
      721 ttccaaaaat tcttttacac gtacaccaac aacaatgaac ccctcaaaac gccaatttct
      781 ctgaatagtt ttaacatctt ctgctgaatt aacattatgc accaatacaa aataaccatg
      841 attctttgcc tgttcctcaa ttccagacaa aacttctgcg gtaaatggat cagaaaatac
      901 aaaatcagca ttatcaatag ccgaaaaata aagcaatcct attaaaaatg caatcgtctt
      961 accgattccc tgacagacag aacacattcc actaggatca ttaaatgaat aagcatttgc
     1021 atatcctaaa ctaggtgttg caaaacatga aaacaacaca cgaaataacg cattgatgtt
     1081 agtaatcgtc cctaacgttg agcgcgcact gccaccaatc ttcttttgat tgaccacaat
     1141 cgccgtagaa agattatcaa tctcatcaac ctctggacga ctgtatttag gtaaaaataa
     1201 acgggtaaaa ctatcatagg tgtcattcag ttgacgacca gcttcttggg taatagtatc
     1261 aaaaacaatc gatgattttc ctgaaccaga tacgctggta aaaatactaa ttttattttt
     1321 gggaattttg agactgacat ttttaagttg tttctcttgc gtggataatt tcaatatact
     1381 cgttcatttg gtactcccct ttattttgaa atagttgaga atgtttcaat gagacacggt
     1441 atttttggca gatgtttagt ttacctagaa agaggtataa aaatcaagaa aaaaagagag
     1501 gctgactcat aagtagtttt attagtcgaa aatgatagtt tataaaaata ggaaccgcat
     1561 caaatcaaca ttctttagaa tggatttgat gcgtttttct ttattttttg acttatgagt
     1621 caacctctta ctcttcgtca tggatttgat tagctaatta ttgctccact tgttcacgaa
     1681 tgaaatttaa gtactgcggt aaaaataaag gaatttcttc aaagcgtgga ctttgatttt
     1741 catacgcttt tgcatctagg tttccttccc ctgtagcaat ttcaatcaat aattgatttg
     1801 ggtcacgata ataaagtgat acaaaaaatt cacgatcttt tattcctgaa tttataaaat
     1861 tgcgctcttg taattgtttg tcgatgcgtt gtaaatcaga tttattttct acgccaaacg
     1921 caacatgatg gacgctacca atcccttcaa tggcaactgg attctcacga tcttgaataa
     1981 tctgaacttc ttgatagaac tgagtgtctt gattttctaa gattgtcact cgttgatgac
     2041 ccgaaaagaa actgacgtat tctttgtgct accagcctac cgacaataac tctcgttcag
     2101 tcgcatcgga atattgtacg cgtagttgaa tggcatcaat tcctaaaatg gcatgctctg
     2161 tagggatctg gtctgtgaca tacgggaaat aatcatcaat atcttcaaat tcgcgtaagg
     2221 gaactaaagc taatcgtgtt gcatctggcc cttcaaaacg taagataggt cgtccagaaa
     2281 atgattcgat tccataatgg caaacgcctt gtgtttcaaa atatatttcc caaaaatgca
     2341 atgatgcttc ggaaggaact tttagtatcg ttcgttcaat cgtattggtt ccaaaaaact
     2401 ggttgttccc ttcttgtact tcaaaaaaag tcagttcagt tcccacacgg tggtgattat
     2461 ctgaaaaaaa caggtgatac atggtatgat cgtcttgatt aattgttttc attagtaatt
     2521 ttaaaccgag tatattatga taaaagtcaa atgtcggtcg aataaagcga ttcacaatag
     2581 aaatgtgatg aatacgtgcg ggcataatat ctaaaaatga gaatcaaacc tataaaagat
     2641 ggtgaacaac ttttgttttc atcagaagaa aataagcccc tttatttaga ctatgtaaat
     2701 cacaatttga aaatcatcat taaagagaat aacttaaaac atatcacact tcatggtttt
     2761 cgtcataccc attgtagtct gctctttgaa tctggtgcgt ctgtcaaaga agtgtatgtt
     2821 cgacttggac atacagatat taaaaccact atggatgata tatacaccca tatcgcgaaa
     2881 aagcagacag aggaaacggc aattcgtttt gcagatttca tgagttctac agaggaaaag
     2941 caaggaagtt tgcagaaggt caaaagtatg gtcaaaaacg aaaaaagcag actatcccta
     3001 ttagatagtc tgctaaacgt tgagttatca gtatttttct tattccgcag cgtttgcgtt
     3061 tttgagaccg tattgattct ctttttttaa tttcatcctt ttccaaccta aaaatgttat
     3121 ttaattactt agtttatata acacgaacct ataccaagta ccagtaaccc cagcttttat
     3181 tccgcgaact ttatgaaata aaatcgttct agataaaaat agcttttaat ctttgtcttt
     3241 actgtttata aaaattttta aattatacac ctagtttaaa tccacgaagt gatgctccta
     3301 tttcatcttc agttatacca atgtaccttt ttgtaattgc ttgcgagcta tgattaaaaa
     3361 taaacattaa ggtagcaatg tctctagttt tcttgtagta gtgataccca aaagtttttc
     3421 ttaatgtatg tgttcctata tcatctcgtc ctaatttttc tgctatatct gcatatatct
     3481 gatagacacg atcccttgtt atatgtcgac cttgttgccg actcggaaat aaccaatcat
     3541 tttcttcttt accttcagta tataataaaa tttcttctct caaattatct ataaaaatcg
     3601 gttttcgctt acctgtttta tgttcaacaa taataggctt acttttgcct cgtatatctc
     3661 caacttttaa tcctataata tctgacatac gtaacccatt attgattcca aacaaaaata
     3721 aaaaactatc tctttccgga ttacttgttc ttcttagcca aaactgaaaa tcttgtatct
     3781 cttcatttgt ccttaacggt tgtacattat agctcactat tgtttccctt cttaaaaata
     3841 ttctgagtta atgattatgt atatatttta ccataatcat taacttatat atataaactt
     3901 ttga
//
LOCUS       DADVXK010000158         3872 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.163, whole genome shotgun sequence.
ACCESSION   DADVXK010000158 DADVXK010000000
VERSION     DADVXK010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.163"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(716..3865)
                     /locus_tag="KB909_002727"
     CDS             complement(716..3865)
                     /locus_tag="KB909_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBB6838686.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          800 c          635 g         1361 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc tt
//
LOCUS       DADVXK010000159         3747 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.164, whole genome shotgun sequence.
ACCESSION   DADVXK010000159 DADVXK010000000
VERSION     DADVXK010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.164"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..835)
                     /locus_tag="KB909_002728"
     CDS             complement(<1..835)
                     /locus_tag="KB909_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838687.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     IS"
     gene            complement(838..3087)
                     /locus_tag="KB909_002729"
     CDS             complement(838..3087)
                     /locus_tag="KB909_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6838688.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            complement(3184..3639)
                     /locus_tag="KB909_002730"
                     /pseudo
     CDS             complement(3184..3639)
                     /locus_tag="KB909_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         1186 a          696 c          533 g         1332 t
ORIGIN      
        1 ttgaaattat aaagaatata attcccaagt atagggttcc ttttcctatc cacttattta
       61 ttggtccaaa cataaatcct gctagtattc ctaagatagg cattagagct aaatagttac
      121 tagcattaaa gtttacccct ttaatttcag ttgcaattga tgcaaatcgt acagaaatag
      181 caatactatt cattacgagt aagattgcaa atagaactag ggcaaaaacc attggattca
      241 tcttttcttt tacatgattt tcaggtatgt cactattttc atctctaatt tcaggaactt
      301 ttagcgcgaa taagagagct acaggaaacg caattgcata gactaaaaac gaagccgtcc
      361 aattaatgtt cactaaaact ccagcaagaa aaataaggat tgtctgacct aaagcttcca
      421 ttgaatttct aatacctaat agcgttgctc tagtattgcc agagtataaa gagctgatat
      481 atgtcacagc caatgaatta tatactccta aaccggcacc taatattact cgactaataa
      541 gaacggtttg gaaggtagct gtaaatactg gaataattcc tcctatacca gctaataata
      601 aacctaaaat tattgtcttt ttcattccta ttcttttggc aaagtaacta gataataaga
      661 taaacaaaat aacagttata cttggtgcag ttcctaaaag ttcactttga ctttgtgata
      721 tccccaaaga ctgtttcatt tgtggaataa caccattaat tgcttgagag cttgttaaca
      781 ttagtgaaat acttaagatt gctccttttt gaagtaagct tttttggtta ttcatctcta
      841 cttttcctcc tgtgttataa cccaaatctt ggaatcaaaa tcaaatgttt ctgggcgtcg
      901 attctgatca tttatttgtc cactagatgc atctgaacag actagtcctg ctctcatcaa
      961 ttccattcca gatcgcaaac tattttgtcc tacattataa agtccgtcat tatctaaccc
     1021 ttttaatttc agtcggcggt aaggagcatt tacctcattt aatgttttat aatgagcaac
     1081 aatagccgtt ttcttatcat gactaacaac catccacgcg gtttgattat catcatcgaa
     1141 tggtgataat agtctataaa aagtaccatt atgaattatg gttctatatt ttttataaaa
     1201 ggcaatttgt tcttttacaa tcctcaaatc gccttcactt aattcattta agtcaagctc
     1261 atatccaaat gcaccaaaaa aagctacatt tcctctagtt tttataggtg ttatacggtt
     1321 tgtttgatga tttggaacaa ttgatacatg agcaccaata gacgaaagag gatacagcat
     1381 actagttcca tattgaattt ttaacctttc aattgcatct gaatcatcac tagcccaagc
     1441 ttgaggtgca tagtgaagca ttccaggatc aaagcgccca ccacctgatg aacaagactc
     1501 aaatagtatg ttaggatatt ttgttataag tttttcatat aagcgatata cgcctagtac
     1561 atatctgtgg aatacttctc cttgttgatc tgctgacaag tgactgtcaa atacatcagt
     1621 caatggacga ttcatatccc acttaatgta atctaagttt gattcatcaa tgattttaca
     1681 catttgatcg aaaatatttt caacaacctc atctaaccca aaatttaata catattggtt
     1741 cctaccatga ttaggttttc gattaggtgt agaaataatc caattcggat gtgtgcgata
     1801 taactcacta tccttattca ccatttcagg ttcaaaccat aaaccaaatt tcataccaaa
     1861 actacgaatt ttttctgaaa ggctgccgat tcctctaggt agtcttttag gatttacatg
     1921 ccaatctcct aatcctgcac aatcgttttc tctttctcca aaccagccat catctaatac
     1981 aaataattca ataccaacat caaatgcttt tttagcaata tttaccaact tttcttcgtc
     2041 aaaatcaaaa tatgttgctt cccaattatt aattaagaca ggacggtctt tttctcgcca
     2101 cttaccacga gctaagcgtt ttctaaatag ttgatgaaaa gtttgactca tggcatttaa
     2161 acccttactt gaataaacca gaatcgcttc tggtgctgta aatatttctc ctggattgag
     2221 tttccaatta aatccaaatg gattgatgcc aacttgtagt ctagtaacat cccatgtatc
     2281 tacttctgct tgaattaaga agtttcctga gtaaactagt gctgcaccaa tagcttctcc
     2341 ttgattttca tcagtatttt ttctttttaa agtaacaaat gggttatgct gatggcttga
     2401 aatacctcga gtagattcga ttgattgaat tccttgttgt aaagtacgcg acttaatagt
     2461 tctttctcta ccccaagcac cagataattg ttgccattca taatttgcat cgggtaaatc
     2521 caatgataaa ctgctaatat tctcgattat ttgaatatct tttcctttat tcataactcg
     2581 cgcgctacga gtaataacag gataatctct ataaattgta tataataatt ctacttgaac
     2641 atttgtaact gaatctaaaa tataaacttt caatgttttg ctttcatcat tattatcaac
     2701 ataggtagca ggtaaacctt ctagtttagg ttttccttct tccacttcgt acccttgata
     2761 gacaaaatct gataagcgag agccattttt ctgtagtaat gaaatagcag gatgtctaaa
     2821 atctgttgta ccatattcag gaaattcttg ttttaagtgc tctaacgaat atagcaaatc
     2881 gttttcattt ctataggttg tcataggccg atgatgcatc tcaattagat gactatagtc
     2941 attatctggt aagttctcac cataatataa atgcaataat ttaccatctt ccgatatctt
     3001 aaaaatgtaa cttatctcct gattaaacaa atgaaattgt tggttttctg atcgataaat
     3061 aatattcatt tcattatcct tatacataag ctctcctccg tttctttatt gcattataaa
     3121 aaacgctcac ataaatagta agcgtttaaa gtaacgaata tttatcaaaa tcaaatgttt
     3181 agtttattca ccattaatga ttcctagacc taatctacgt tttcgatata ctcccggtga
     3241 aacaccattt gctttcttaa aggctttaga aaaagattgt actgttgaga atcctatctt
     3301 gtcactgatt tgctggattg aatattcagt tgatgataac agatcgtttg caatagaaat
     3361 tttgatttca ctaatatact cttttattga tattcccata tcattcttaa acaatcgtga
     3421 taaataattt tcgtgtatcg atagactgac agcaatatct ttaacagata atttttgata
     3481 cgcattctca cgtattattt caattgtttg acgaacaaaa ggattcatct ttttagtaat
     3541 tatcccttcg ttcagataac tagctgaatt taagaggagt tctaaaaatt tataaacttg
     3601 tttttgtctg gacaattcac tgactagatt gtcctgatct ttcagctgag tgttaggttc
     3661 tgttactaaa tatatagaat tttccatatc caccctccta tgttagattt ggataatttt
     3721 tgttttatta tgtttatatt attacat
//
LOCUS       DADVXK010000160         3738 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.165, whole genome shotgun sequence.
ACCESSION   DADVXK010000160 DADVXK010000000
VERSION     DADVXK010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.165"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            72..155
                     /locus_tag="KB909_002731"
     CDS             72..155
                     /locus_tag="KB909_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6838689.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="KB909_002732"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="KB909_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6838690.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="KB909_002733"
     CDS             complement(1280..2143)
                     /locus_tag="KB909_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6838691.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="KB909_002734"
     CDS             complement(2145..2417)
                     /locus_tag="KB909_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6838692.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="KB909_002735"
     CDS             complement(2434..2643)
                     /locus_tag="KB909_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6838693.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3638)
                     /locus_tag="KB909_002736"
     CDS             complement(2742..3638)
                     /locus_tag="KB909_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6838694.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1148 a          654 c          579 g         1357 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tctttaaagg gcttttat
//
LOCUS       DADVXK010000161         3737 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.166, whole genome shotgun sequence.
ACCESSION   DADVXK010000161 DADVXK010000000
VERSION     DADVXK010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.166"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(178..342)
                     /locus_tag="KB909_002737"
     CDS             complement(178..342)
                     /locus_tag="KB909_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838695.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            637..1965
                     /locus_tag="KB909_002738"
     CDS             637..1965
                     /locus_tag="KB909_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBB6838696.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2167..3000
                     /locus_tag="KB909_002739"
     CDS             2167..3000
                     /locus_tag="KB909_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBB6838697.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            3016..>3737
                     /locus_tag="KB909_002740"
     CDS             3016..>3737
                     /locus_tag="KB909_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBB6838698.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANI"
BASE COUNT         1239 a          591 c          779 g         1128 t
ORIGIN      
        1 gttaatcatg atgtcgtagg ttcgagtcct actgccggag taaataaagc ttatgcaaag
       61 aaaaagaaat ccaatcactt gggtttcttt ttcttttatt attatgatga atcaagcttt
      121 ctgtttttgt cacgtatgtt gtaatcttta cgaaagagta gagttggcta ctcataatca
      181 accatacttc ccatcatcgc taaatacgaa ataaatcagc attcctacac caatcaaagc
      241 acaagctgca ccaagaaaag ggatgacatt cccaaagtta tctgtattca taagtatgcc
      301 accacccaca aacaaaaagc cgccagcaat caggtttttc attttattca tctcctttct
      361 tacgttatag tatttccttc tttcaatgag tattttgaaa gctatcttat tgtatgatgt
      421 tcttctaggc ctcttcttta ttatacaggc cattttcgtt atctcataga aatattcctt
      481 tttatctgaa aactattgta taccgtatga catttttctt catgaagttg taagtatatt
      541 ctcattcaaa tgaaaatttc atcatagaag agattgtatt tctaaattct taagagtaaa
      601 atacgaagta taacttggat ttggaaggat gattggatga aagctattac gcctgatatg
      661 acaacaaaat ttaacaaaca gtttcaagca aatatcaaac agcaggcatt gcagcgggca
      721 gttgtgaaga acggaattac tgcttctgct gaaaatgttt cagcacatgt ggagaataca
      781 ccggtatttt ctatagattt ggctacgggg aaagtggcta atcaaatgca atcggggcgt
      841 tgctggatgt ttgctgcact gaacacattc cgtcataaga tgctgaatca attccattta
      901 aaagagtttg aattatcaca aaattacact tttttctggg ataaatatga aaaggcaaat
      961 tatttctatg aaaacatcat tgcaacagga aaagaggcaa tcgatagccg gaaagtagct
     1021 ttcttactcg ctactcctca acaagatggc ggccaatggg atatgatcgt ttcattattc
     1081 caaaaatatg gcgttgtgcc taaatcggtg atgccggaaa gtgcgaatag ttcaaattct
     1141 cgagatttga ataactactt gaacaaatta ctgcgtaaag atgcagtagt gttacggaaa
     1201 atggttgctc aaggagaaac attagacgct attgaagaaa agaaagaaga aatgctagaa
     1261 agcatttata acttcttagc tatctcatta ggaacacctc caaaagaatt cgattttgag
     1321 taccgcgatg aagaaaagaa ctatcatctt gaccgaggac tgacaccaca aattttttat
     1381 gataaataca tcggtgtaaa attagatgat tatgttagcg tgatcaatgc accaacaaaa
     1441 gacaaaccat tcaatcgttc ttatacagta gagatgctag gaaatgtcgt tggcgggaaa
     1501 gaagtcaaat atctgaatgt tgatatggaa actttcaaaa aattagcgat tgctcagctt
     1561 gaagaaggag aatctgtttg gtttggttgt gatgtaggtc aatcttctac tagaactagt
     1621 ggcatcatgg ccttagatgc ttattcaatg gatgatctat ttgatacgga ttttacaatg
     1681 actaaagctg aacgtttaga ttttggagaa agtctgatga cccatgcgat ggtattgacc
     1741 ggtgttgact tagtagacgg gcaatcaaca aaatggaaag tcgaaaatag ctggggcgaa
     1801 aaagttggaa agaatggctt ctttgttatg agtgatgcct ggatggacga atatacgtac
     1861 caaatcgttg taagaaaaga tttattgacg aaagagcaat taaatgcgtt caatgaagaa
     1921 ccaattgttc tatctccgtg ggatccaatg ggtgctttag catagacgag tatttcaatg
     1981 aagagtatgt agtaaagata aaaagagctg gcttaagcca gctcttttta tctttaaagt
     2041 ccattccctg ttttttatgg tccctgtgct ataattctaa ataaaggata aggattggaa
     2101 ataatccttt tatcattaaa aatatgatga cgaagtagaa taaaattggg agtagggggg
     2161 aaagtcatgg atatccaaac tgttttatct gatctgaaat taaatggtaa agtgattcca
     2221 gttgttggtg gcgatgttaa tcagacctat cgtataaaaa ccgaacatcg tgcttatttt
     2281 ttaaaaatcc atccgaatgt aaaaaaagga ttttttgaag cagaagtaga cggattaaaa
     2341 gaactgtcag cattcgtacg tgtaccggat acgtatatgc taggtgaaac aagtgaaggc
     2401 gcttatttgt taatggaatg gatcgagccg ggaaaagggg atcaacgaga tcttgctgca
     2461 gctttagcta atctccatca gcaaacagcg ccacaatttg gttttcgtaa agataactat
     2521 ttgggtacac ttgttcagaa aaattctttt gaagaagatt ggtggacttt tttctttaaa
     2581 gatcggcttg aatcccagat ttctttggca gaagaaacga atcgatggaa tgtacagcgt
     2641 caagaaaagt atctgcgatt taaagaacgt gtattgaaat cggttgaacc aaaaaagatc
     2701 actccacgcc tcttgcacgg agacctgtgg agtggtaatg tgttctttga ccagcaaggg
     2761 catccagttt ttgtcgaccc agctgtttct tatgggaatc gggaacaaga tattgcaatg
     2821 agccagttat tcggtggttt ccgaccggaa tttttagatg cttatcaaac tatatttcca
     2881 ttagaaaagg gatggaaaga ccgactgccg atttaccagt tatattatct tttggcacat
     2941 ttgaatatgt ttggagaaag ttacggttcc caagtagatc aattactaga aaatttttaa
     3001 gaggagggcg tgtttttggc aaaaaaatat accaaaaagc atgaagtttc atattatgag
     3061 tgtgacatca accaaacgat gacatttcct tcgatgttag gagtagttat caaaacgtct
     3121 gaagatcaaa gcgaccagtt gggaagaggc agtgaattcg tcaatagctt tggacttact
     3181 tgggtcatca cgaattattc catggagatt aatcgtctcc ctagagtcgg tgaagtaatc
     3241 tcagtaacga ctcaagccat ggagtacaat aagtttttct gttatcggaa cttctggatc
     3301 catgatgaag atgggaaaga attagtcaaa atagaatctg ttttcgtatt gatggatttt
     3361 gtgaatcgaa aaatgagcag tgttaatgaa gagatcattg ctccttttga gagtgagaag
     3421 atcaagaaaa tcaagcgtca ggaaaaaatt gaaaagattg attcgggctt catgttgcca
     3481 tatcgtgttc gtttttatga tatcgatagt aatcagcatg ttaataatgc gatgtatttt
     3541 aattggatca ttgacgtatt aggatatgac tttttgacta cgcatgttcc agaaaaagta
     3601 attattcgat ttgataaaga agtagagtac gggaatgaga tcgaaagcca ttttgaacaa
     3661 atccctatcg aaaatggtgt caaaacaaaa catgaaatcc gaatgcaaga acagctgtat
     3721 tgtgaagcaa atattat
//
LOCUS       DADVXK010000162         3715 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.167, whole genome shotgun sequence.
ACCESSION   DADVXK010000162 DADVXK010000000
VERSION     DADVXK010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.167"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..353)
                     /locus_tag="KB909_002741"
     CDS             complement(<1..353)
                     /locus_tag="KB909_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838699.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(613..1161)
                     /locus_tag="KB909_002742"
     CDS             complement(613..1161)
                     /locus_tag="KB909_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838700.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1162..2019)
                     /locus_tag="KB909_002743"
     CDS             complement(1162..2019)
                     /locus_tag="KB909_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6838701.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2305..2591)
                     /locus_tag="KB909_002744"
                     /pseudo
     CDS             complement(2305..2591)
                     /locus_tag="KB909_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2581..2910)
                     /locus_tag="KB909_002745"
     CDS             complement(2581..2910)
                     /locus_tag="KB909_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6838702.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2987..3259)
                     /locus_tag="KB909_002746"
     CDS             complement(2987..3259)
                     /locus_tag="KB909_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6838703.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3259..3522)
                     /locus_tag="KB909_002747"
     CDS             complement(3259..3522)
                     /locus_tag="KB909_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6838704.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1089 a          754 c          473 g         1399 t
ORIGIN      
        1 aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga
       61 tctcgcttat tataatcgct ttcatttatc ctaagagtca aatctttttc caccataact
      121 tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt
      181 aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata
      241 atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac
      301 atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc
      361 tcctcctaat agttttattt tagagttagc tctattactt atttactaac tcaacaacag
      421 attatcatac acttgttaat gaaatcacaa tatctcatta aaacacaccc taaaatcata
      481 accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct
      541 ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt
      601 cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc
      661 ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg
      721 aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc
      781 ttgcttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa
      841 ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa
      901 caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg
      961 tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat
     1021 ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt
     1081 tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc
     1141 aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa
     1201 ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc
     1261 tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt
     1321 gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc
     1381 ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt
     1441 tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat
     1501 cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt
     1561 actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa
     1621 tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt
     1681 gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat
     1741 tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt
     1801 ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt
     1861 taagttcatc acatcagaag tatttccttg catatccaag tcaattatca aggttctttt
     1921 tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc
     1981 acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc ttttctttta
     2041 gcaatattca tttgatacta ttataacata tttattttta gttactacca aaaaaaagat
     2101 atatatgtac taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga
     2161 aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag
     2221 agaatactcg cgactttagt catgtagacg aatcagattt tcgataaaaa agaagccgtc
     2281 cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc
     2341 atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt aagctactct
     2401 atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt
     2461 ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc
     2521 tttcaatggc ttctctttta gctttttaaa tacttaatga catgttttga aggaacgatt
     2581 tcataagcca atttctgttg ccaactcctc tttagtcatt actttagaat tagtaagtgt
     2641 atcttcagca atatctctaa aggaagaatg cattttgttt tttctattct taaattctac
     2701 aagaatctca tctttatcgt agccttctgc aattatatca gacaaaatat cttcgctaaa
     2761 atcataaaat tctttttgtg gttcaacaaa ttcataaaga ataccattct ctaccaactt
     2821 tgcttcaact tcgactccat taggaacatt aaaatcttta ggtactgtca acatgattga
     2881 attgccttgt tttcttgttt ttgtaatcat ttaaatccct catttctaac agtatgtaat
     2941 tacttagtaa atacattata ccacgagata atgtatttac aagtaattac tgtgactcgt
     3001 aatgcgtcct tgctgaataa atttcaacca cgtgttcatc ttcatctacc ttataaacaa
     3061 cccggtgttg tctattcaat cttctagaat acctaccttc atgtgtaggt tttaacttct
     3121 caaatgattg ggtagggaga tagggatctt cctttaaagt ctgaataacc ttctcaaatt
     3181 gaggtttcaa attagactgt ttgattttct ttaaatcagc tttagccgag tttttaatca
     3241 tcacagaata gttattcatt ataagttatc ccaatcaatt tcatcaacat tagtaaatcc
     3301 actatcatct ttttctcgct tacgaacaac acccaaagtg cctatttgct caagtaatag
     3361 cgtttctttg attgctttcc aatcatccaa accaataagc accgcattat tttcactgcg
     3421 ctcactaatg atttcaattt ccgtatgatt ctcatttaca tctttcaaca acttataaaa
     3481 atttttccgt gctgagctag gatttaagac tgtttttgcc atatctactc cccctctaat
     3541 ttatatctcc attctaacgt acttaattaa gtacgtaaat tcgattgttt tgtttaaatt
     3601 ggagtaccaa aacagcattg taaagtgtta tccgtttcct ttatacccgt ggtgctagtt
     3661 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa aacgc
//
LOCUS       DADVXK010000163         3627 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.168, whole genome shotgun sequence.
ACCESSION   DADVXK010000163 DADVXK010000000
VERSION     DADVXK010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.168"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            127..579
                     /locus_tag="KB909_002748"
     CDS             127..579
                     /locus_tag="KB909_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838705.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="KB909_002749"
     CDS             593..1282
                     /locus_tag="KB909_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838706.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..>3627
                     /locus_tag="KB909_002750"
     CDS             1407..>3627
                     /locus_tag="KB909_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBB6838707.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     "
BASE COUNT         1223 a          482 c          753 g         1169 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattg
//
LOCUS       DADVXK010000164         3493 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.169, whole genome shotgun sequence.
ACCESSION   DADVXK010000164 DADVXK010000000
VERSION     DADVXK010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.169"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(45..1511)
                     /locus_tag="KB909_002751"
     CDS             complement(45..1511)
                     /locus_tag="KB909_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBB6838708.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="KB909_002752"
     CDS             1898..2494
                     /locus_tag="KB909_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6838709.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="KB909_002753"
     CDS             complement(2552..3034)
                     /locus_tag="KB909_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838710.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="KB909_002754"
     CDS             complement(3140..3337)
                     /locus_tag="KB909_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838711.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT         1179 a          703 c          575 g         1036 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctgaggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta ttt
//
LOCUS       DADVXK010000165         3445 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.170, whole genome shotgun sequence.
ACCESSION   DADVXK010000165 DADVXK010000000
VERSION     DADVXK010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.170"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1838)
                     /locus_tag="KB909_002755"
     CDS             complement(<1..1838)
                     /locus_tag="KB909_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6838712.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
     gene            complement(1835..2575)
                     /locus_tag="KB909_002756"
     CDS             complement(1835..2575)
                     /locus_tag="KB909_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6838713.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            complement(2565..>3445)
                     /locus_tag="KB909_002757"
     CDS             complement(2565..>3445)
                     /locus_tag="KB909_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6838714.1"
                     /translation="EVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWI
                     DLKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIV
                     NSAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDT
                     IKGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKT
                     PSVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTR
                     QMKRDAGAVGGTLYAT"
BASE COUNT         1081 a          656 c          412 g         1296 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcac taggataccc accagtagat
       61 tctccacctc ccgatggacc accaccttgt ccaggaatta tttcttttcc tttaactgta
      121 agttttcctt gtacatctaa gtctccaaaa taaattgctt taccatttcc taataaaact
      181 aatccttttc ctactttagg agaaatcaaa atatatttgc cgtctccatt tgtacgaata
      241 actaaagaat tatcttcaat aggggttgga gtagaagccc caggaaaagg attaccaaca
      301 gaatcagttg ttccaatcgt tccaattgaa cccttagaat tccaaaattc cattcctttt
      361 ttagttaact ccattatttt ctttttgttg ttccaaattt ggagtagtcc attaactaat
      421 ttcaatacat ctccagtctt gttaaaagaa ttttgaaaga tatctgcttt gattaatcca
      481 gtttgtataa aattggcatt aaatatacta tctaatgtcc aagctgaatt aaaaggcccc
      541 cgccatcctt tcttagaaaa agcaatccca tttttattca ttcttagtac ttctcttgcc
      601 ttttctaaat ctggattatc cataataaag atgttggaag gtttttcttt tggccataaa
      661 actacatatc ctcctgcact gccttgacct gtaatcattg aagaaacata atcattaaaa
      721 tcactcatat aattattcgt tgcataatct tttaatttat cctgaatagt tacagcttgt
      781 tgctgataaa aagcaacttg aatgtctcct gcttctaatt tcaaagtttt ttcagataaa
      841 gaatcgtatt gtagtccact aacctttgat tcaagataaa tattatattt tttatgatat
      901 attttaaatg tatcaaacag accataattt ctaatcttcg caaattcttt cgcttcttca
      961 ctatcagtca acttatcaaa ttcaaccgta atagaaactt taggcttatc acagccagga
     1021 ttgatcgttt taaagtaatt tttagctatt ttatttaagc tcttaatgtc ttttactcct
     1081 tgttcttctg taaactgaac atgttctgta tagacatcag gatagttatt aatataggca
     1141 ctatctactg gcgaaccata aattcgatta gtcgtaccta cttcactttg aggatcagca
     1201 tatggaataa ttcttgtttt tatacctgtc caatctaatt tgaccttcaa accagacata
     1261 tcttttccat accgaatcgt tccaacatta ttgcgacctc ttcgctttaa caaagaaagc
     1321 ttaaatggtt cacgtttaat ttctccgccc caatattgaa gcaatgatcc ttgttcacca
     1381 gcaatacaat ttaaaacatt tctcgcttca aagattgtgc tagaaacagc cgtaatatca
     1441 gaataaagtc gtatgtcaga ttttttatcc attttagttt caataattga tatcgcttct
     1501 tgaccagttt tagagtccac ttccacaaga gtgactaccc gtcttccaag tcgatttgta
     1561 cgactctgag cataaatagt tactgtattt aaaaaagtat ctatatcttt atcatcaata
     1621 aaaaagatat gatactcttc ttgatcgttt ggctttgctt ttatttgata gtcattttca
     1681 aaatattcat caaatctagt tcctaaagga taatccaact ctaattcata ttttccatta
     1741 gctacttcat atatttcaca tcttgtacaa tcctttaaaa ttcctaagcc attcgttgag
     1801 aaatctgttt cagtaggact atatattctt ggtttcatac ttttctccac cacctaggca
     1861 ttatttcaaa tgaatgaata tttttcgtcc atttaatttc attttttcca ggatataaaa
     1921 atggaaaatc taaaaataag gtgacctgat cctgatgttc taaattacca tctaattttc
     1981 gataagcctc ttctaattta gaatctataa ataattctct gtccaacgat ttcaaatcat
     2041 atttatcctt attaatataa aaagaagcat ctccagaacc actcaattta ataagcggtt
     2101 ttgaagaata cttctctggg ttataaattt caaaagtttc tgtttgtcga atagtaaatc
     2161 taccattgta attttcctta aatggtcgaa tactcactgt aaattcaaaa gggacaatat
     2221 ttcctgtttt tcttgttcct ttaaattcag gtccttctat tactacagct tgataaatat
     2281 attgttcatc atagtaaaga ataaaatcac tataagacga catatctaac cattcagtga
     2341 ttcgatcttc ccactcctgc accatatcaa ttgaaggtgc tttatagtaa cactcaatct
     2401 ttctagtcac atttttgtaa tagcctttat caataatgat agaatcattt ccttctcgct
     2461 ctctcaattc aattactcga ctagctgaaa cagaagcagg cctgttttga atatacacat
     2521 taaattcaga agaataatgt tgattaataa aaaattgtcc tctcttaagt tgcatataat
     2581 gttcctccta ctgcaccagc atctcgtttc atttgtcttg tcaattctgt tttaattttt
     2641 gtagtaatct ttcgaaccat tgaatcaggt aaatctccat aaacatttaa atgtaaatga
     2701 atttcttttg tttcactagc agatatattt tgctttgttt gtgtaattgg taggtgactt
     2761 attccattta ctacaggttg aacagacggt gtttttacta aatttgtcat ggtttgatct
     2821 aacttacttt gctctttatc aataccaacg ataatacctt gaacaatatt tttaccaacc
     2881 atatcacgca tccatcttga tggagaatga atatctaaag ctcctttaat ccaatttttg
     2941 atattacctg caataccttt gatagtatct ttcaaagcat tccacttttc ttttacacca
     3001 tttataagtc catcaatgat gttcttgcca atttcaaata aattgacttc ccttaacgaa
     3061 ttaaagattt cttttacccg attaatagca tttgaaacac cattttttag atttgtccat
     3121 gcattttcag cagaattaac aattccagta acaatattcc agaaagagtc cttaatgtta
     3181 ttccatgtat taatcatggt attttttata gaaatccacg tattgtatgc cgtatcttta
     3241 atatttttcc aagtatcttt gaaaaactgt ttaatattat tccaagtagt aatggcatta
     3301 tattttaaat cgatccaagt ttgaataata gaaaacttca attcaatcca tttctgaatt
     3361 gcaaaatatt ttatatcaat ccaaagatta ataaaaaaat actttatgtt taaccaaatc
     3421 gatttagctt gatttaccac ttcat
//
LOCUS       DADVXK010000166         3406 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.171, whole genome shotgun sequence.
ACCESSION   DADVXK010000166 DADVXK010000000
VERSION     DADVXK010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.171"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            155..1195
                     /locus_tag="KB909_002758"
     CDS             155..1195
                     /locus_tag="KB909_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6838715.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2019..2351
                     /locus_tag="KB909_002759"
     CDS             2019..2351
                     /locus_tag="KB909_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBB6838716.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            2970..3311
                     /locus_tag="KB909_002760"
     CDS             2970..3311
                     /locus_tag="KB909_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBB6838717.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1266 a          460 c          646 g         1034 t
ORIGIN      
        1 aaggtagtac ataattcatt ttatttctga ttttaggtag tatttaatta aaaaacagtt
       61 ttaatgcgtt tgcatttttt atttatcttt gctattttcg aaaagagtag gtaattttac
      121 ataaataaaa caacgtgaaa gtagaggatc tacaatgact gattttaaat tttttaaggc
      181 ggatagagtt tacaacgaat tattttatca atttccaaaa gtctttattg tttctgacga
      241 atacaaaaaa atgaaagatt caactaagat tgcctatatg cttttaaaag caagattaga
      301 gatcgcaatc agcaaacggc aaatcgatga agaaggtaat gtttatttta cttatacgac
      361 aaatgaacta tgtagagtat taaactgcca aaaacaaaaa gcgatagcaa tcaaaaaaga
      421 gttggaatcc tttggtttat tattacaaaa gcagatggga tttaacaaac agttagggaa
      481 aaataatcct aatagactat atctagcaga attaaaagtc tcagaaaatg atatctactt
      541 actcgaaaaa tttgatagag agaataggga aaacgttgat aaatcagagg gtatgaaaat
      601 catacccacc ctcgacgaaa aatcagacgc tgaatccctt ggggctcaag agggtatgaa
      661 aatcataccg tgccaaaacg ttgataaatc agagggtatg aaaatcatac cagaacttaa
      721 taataatata ttagacacta atagacacaa tatagacact gaaaaagacc gcctacaaga
      781 tcaattgttg ttagacaatt ttgagacaat tatgacaaac gacagcattg ctacgtttgt
      841 ccctgaacga gtattaaatt tgataaaaac attttcttca agttacagtg aagctcaaaa
      901 aaccgtccag actattcata atgcaaagaa aaaagctgaa atagaaagtg atatttcgat
      961 agtttttgaa gaactcgata gttattatgt caatgcagaa caagaattat acacgacact
     1021 gttaaaagcc tatcaaaaat taaaaaccga aaaagtcgaa aatatccaga acctgatttt
     1081 tgtctatgta aaaaattggt ttatcgaaaa accaatagct gctaaagtat caagtgaaaa
     1141 acgtttgaat tatgcaagct ccccaagcac tattacgaaa gactggttag agtgaaactt
     1201 tactgacaaa gtgattgttg cttcatggag taacattaaa attaaaaatt ttttattatt
     1261 ctaattatat tacgaatatt acaaaataat agctatttta atagaattta taagttaaaa
     1321 tattatgata aaaatcacaa acgtagcctt ttacgtcata agtgttaaaa gaaataatta
     1381 atttcaaata tagaaaaggg aacgtatgtt tgcatactcc ttttttttga gttataataa
     1441 tacgcgaaga gagataattt cattatttaa acaagctaaa aatcttgata ttacttcttt
     1501 tcaggcaata cgaatattat tcgcttacat tttttgtata aatttaattg tctgctatgc
     1561 ttgtgatgaa ttgattttcg ttttgcactt ttggatgata aatttggaca attgaaaata
     1621 caaaaaaaag aaaggcggta tgaactcgga aggctggtaa ccttcgtcag cgttcataca
     1681 cggcattaag atttggccct taatgcgtta acctttcagt gttacggtat tacccgcaat
     1741 ggatttagta taacagatat tcaaaagtga taccactttt tttggctgtg ttaaggttaa
     1801 aaatacgtga tattacgatg aatctatgcc taagcataat gttataaaaa tgtccgtgtg
     1861 gctctttgcc gtatgacgaa cgctgaaatt agagggaacg catgtttgga tgcgttccct
     1921 cttttttgtt tgtcatgaac gaaaatcaat tctctatttt tgaaaaataa caagaaaaac
     1981 ttgttaaaaa tatttaaaga aattgggtgg tttattttat gtcatataca ggaattttga
     2041 gtctcaaaga tatttgtcac tacggtaaac ggtgtaccgc tacagagaaa atcacgaaga
     2101 aactatcaac tggccaaagt aaaaccgttg tgcagtgtaa gaaatatata atccagaaag
     2161 acaaagtctc agaggaaatg atttattaca ttgggaaaca aaagcaaata attttaaaag
     2221 atcctatccc cttaaaagag ctatatccaa caatcaaaca tgtttatgac caaaacggtg
     2281 tactgattgg tcgaagaaaa aatggagtct tgcgttgtac cgcaaaaggg atggggcgtt
     2341 tgatcggctg aattgatcat tctcataact tgtattttat cgtttttcgc ttgcttgaaa
     2401 atattgtcga gacttctaaa ggaacttaga gtcactagaa aaataaggag tagacttgat
     2461 ctatcaacaa ttcccttcgg ggagtgacgg ggtaggtttt aacgattggt aacgtaaaaa
     2521 attggtcaat cgagtaaatg cgcttgtttg gatagtggtg aaatgaattt gtgtaaataa
     2581 taagcgcaga gtaaacaaga gggaatttag aagttagaca agttagaata gcgtctagat
     2641 taatcatgag cagctactaa gggatctaga ctttgacgca aactcatgga ataaggagta
     2701 ggtcttctcg taatggggag gacgcacaag aaattgtgtc gtgtgctgca gtacatgtag
     2761 atacttgcga ggacgttgat tattggatca atcgagcatt taccgctgtc tactagggtt
     2821 tctcgtttcg gacgccataa acgagtcgaa attttttatg tatttttaag taaacgaaaa
     2881 acgataaaat atgaacaagt cctgaataaa gtgaaaaaat tgatataaaa catagagaaa
     2941 atgaaattta cgtaatggag gaatgacaaa tgaaaaatta tgatccgaat atacgattgg
     3001 gcacacatac tattaaggtt tctttccaac gttgggatta caaaggattt gtgacgttta
     3061 gaaggggcgg aaattgtaaa ggattagatg ttttagcatt agacgaggat gatttatacg
     3121 atcaaacatt gactgataat ccaattggat tcggcttgct acctgaagat gatgaaggta
     3181 atgaatggtt taaaatgacg cttatgaatg ataatggaga cgaattatct gttgaagata
     3241 cttggtcata tttgagtgat tatattgtca gctttgaaat cattgaattt gtagcggata
     3301 aagaagaata aaaactggag gaataaattt tacagataaa ggcttagaag gagtcacgac
     3361 gattaataaa aaggtagtat taccttaggc attgagtaag gaattt
//
LOCUS       DADVXK010000167         3331 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.173, whole genome shotgun sequence.
ACCESSION   DADVXK010000167 DADVXK010000000
VERSION     DADVXK010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.173"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            246..503
                     /locus_tag="KB909_002761"
     CDS             246..503
                     /locus_tag="KB909_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBB6838718.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            735..1139
                     /locus_tag="KB909_002762"
     CDS             735..1139
                     /locus_tag="KB909_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBB6838719.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            1158..>3331
                     /locus_tag="KB909_002763"
     CDS             1158..>3331
                     /locus_tag="KB909_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6838720.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGT"
BASE COUNT         1217 a          444 c          624 g         1046 t
ORIGIN      
        1 gatggaaaat aatattaatt atattgactc aggttcagat ttgctgatta ggtggcaggt
       61 aataactaat tttcttatgg aattaaaaaa atacagtaat actcaaacga agttctcttg
      121 aagttataaa gaatacaata aatataaatt tcctttagac tatattaaaa tcagcaatcg
      181 aaggaaaata aaagaagaaa atggtacgca aaatctaact attagagcaa aaacaggaag
      241 ctgctttgga agatagtccc gaattgtttc cgatgttaaa agatcgttta aatgaattga
      301 ctgaaaaacg aagacagtta caaattcgag agaatgaaat cttagggatc tttcaacaac
      361 aaggggaacc gattcaagtc aaagatgtcc aacagatatt gactagtttg gattgctttc
      421 ttatccagag tgagaagaag caagttaaag ctttgtatca cacctttatt gagaaaatca
      481 cctttgatcc taatcagaag tagatattgc cgatcccgat gagattcaca cctactgtga
      541 tttgataatt gaatgagtaa tatcaaatag ccgtatccaa accaaaggat atggctattt
      601 ttgtgttagg gatatacgtc acgtagcttg ttatcaagaa taagtttctt tatttttttg
      661 ctttttctaa aactgagtat gctaaaataa gagggtatat agcaacttta aataagagat
      721 aggagtgtat ctttttgggt gcagaattaa atcagaagtt atttagtgcg gcagataatc
      781 tccgtagtaa aatggatgcg tcagaatata aaaattattt attggggctg attttctata
      841 aatatttatc cgaccgtttg ttggaacaag tggttctttt agcagatgaa tccttagagg
      901 aatatgacac agtaagcaaa caaacgatgt tgtatcgtga attactttca gatgaagaat
      961 caaaagaaga tctgattgca acaatcgttg atattttggg gtatgcgatt tcgccagagt
     1021 atcttttcaa cgtcttagcg gatcaagcaa aacaagcaac gttccaattg aatgatctaa
     1081 acaaagcctt tttagcaagt catatttatg gaaaaatact gtcggcaaaa ttcgaatagt
     1141 gtcgaggagg tgctgtgatg gaagaattaa aagaacgcat tgtcaattat gtcatagaga
     1201 actctgagat taaaaataaa tgggggaaca atacagcaca gaaaatatct gaaaaattaa
     1261 atgttagtcg taatattgtc tctcaatatt tgaatgaatt cgtaaaagat ggagaatttg
     1321 gaaaaatcaa tactcgtcca gtaatcttct tttctttacc ggagaaagtt ccaaatcaac
     1381 aaatttttag ctcttcagag gaagcggaaa aatggtatga tagctctttt agggttggaa
     1441 tagaaagggt tatcggaagt caaggaagtc tgcgaaatgt aattgctcaa attaaagcag
     1501 caatctacta tccgccaaat ggcttaccca ttttacttca tggcgagact ggaactggaa
     1561 aaagctattt agcaaattat gtgtataagg atttgttggc caataattat atagaagaga
     1621 aggcatcttt catttcagtt aattgtagtg aatatgccaa taatccagaa cttttcttgt
     1681 ccaatttttt tgggcatgta aaaggtgcat atacaggagc cgaagatgga agaaagggtt
     1741 tagcagaatt agctaataat ggagtcttat ttttagatga aattcatgca ttgagcaatg
     1801 aatgtcagga gaaacttttt cagtttatgg atacgaggaa atttcatcgg atgggtgata
     1861 atgaaaactg gtacacatca agttgctgga ttatatttgc aacatcagaa ccacctgagg
     1921 ataaactatt atcaactttg ttgagaagaa tacctgtaaa gctaacactt ccaacattag
     1981 acagtcgttc tctttatgaa agaaaacagt taatcaagat attttttaaa tcagaagaag
     2041 aaagactagc aaagaaaata ctgatatctc aacaattatt agatttttta ttaaactatc
     2101 gctttagtga aaatgttggc aatttgaaaa atatcattca attgacctgt gccaatgcct
     2161 tttatttctt agatgatttg gaagaacttt atattcagat gtatcattta ccacaatggg
     2221 tgaatttcaa cggcatgaag gttatgaaaa gacagaatga attaaaatat attcaaatgg
     2281 atgatttgga aaaagtagac gaagttttta atatcaacga acttatagag tatctttatc
     2341 aaacgtggaa gaaagacact gataagcagc agctttttga gaaatatgat agatatttta
     2401 gacaaaagaa tgttgatatc caaaataatt cagctttaac atatcccacc tatcaagaga
     2461 ttcgatttag acagtatgtt aaggaaatag agagagattt tcaaatagaa tttgactatt
     2521 attatcttca aataacgtct atctttttga attcttggat ttatcaaatc caattaacat
     2581 cggacgataa attatattcc ttcatcaatg atattaatag ttggtgtagt cgagaagttc
     2641 aattagtcaa tcgttttatt caaatagggg atatttattt aacaaaaatt caaaaaaatg
     2701 ttttggttat tttatttaag ttaatgtgta gtaaagaatt tcagcaaaaa cgtttagcac
     2761 tgattttggc tcatggagat ctaacggcaa cctgtatagc aagtactgct aataggatcg
     2821 ttgagagata tatatacgac gccattgata tgccactaat gacttcaagt agtgagattg
     2881 cagacaaaat taatagatac ttacaagagt gtaccggata tgaagaaatt attttacttg
     2941 ttgatatggg ttcactggag aaaatttatc taaatttgga actagacgct caaaaaaaat
     3001 tcggactact aaacaatgtt tcaacaagaa tggctattga tgttgcaaat cagatattat
     3061 tagatttacc gcttaaacag attcttgaac aagtaaaaga aaatcaaaat gtggattata
     3121 tttatgaatc atcaaatatt aagaaggata tgattgtctg ttcttgtgca agcggattag
     3181 gaacttcgtt taaattaaaa aggatacttg aagatagctt tccaagggat actgatcttg
     3241 tcatagaaac gtgtgactat tactctttag tgaatgaaaa ctatttatcg gagcttcgta
     3301 aagagaacaa tattcttttt attgttggaa c
//
LOCUS       DADVXK010000168         3312 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.174, whole genome shotgun sequence.
ACCESSION   DADVXK010000168 DADVXK010000000
VERSION     DADVXK010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.174"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            92..907
                     /locus_tag="KB909_002764"
     CDS             92..907
                     /locus_tag="KB909_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838721.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1033..1290
                     /locus_tag="KB909_002765"
     CDS             1033..1290
                     /locus_tag="KB909_002765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838722.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1542..2114)
                     /locus_tag="KB909_002766"
     CDS             complement(1542..2114)
                     /locus_tag="KB909_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6838723.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2130..2735)
                     /locus_tag="KB909_002767"
     CDS             complement(2130..2735)
                     /locus_tag="KB909_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBB6838724.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT         1092 a          612 c          505 g         1103 t
ORIGIN      
        1 aattaattac ataggataat atattaaggt gctggactac aagtaaaaaa tactgtatga
       61 tcatgacaga ttcaagaaag gagcaataag attggttaag atagcaggac tttctaaagg
      121 tggaaaaacc gtttcacaac tttataaaca aaactacaga gactggagac agttcagaaa
      181 aaacattaag gattcttact ttattctacc aacagaactt gaaaaatatt taccgaataa
      241 caaagctatt aatttatatc tgtattactg ttttaaggca aagaatgaag gcggggattc
      301 ctggcattcg gtcaatacca tagcagagtc tctaggagtg acaactaaaa ctataaacac
      361 ctggaataaa accttagttg atttaggtat gattgcacgt atagacgata accatctcag
      421 taaatcgaca attttacttc ctctctctag ttactataaa ttagcccttg atagttcttt
      481 aaaggatgtt accgagagca ctgtccatga aattgatggc aacttggttg cagtttatca
      541 tttgtttgaa tggagaaaaa atgaggctga tgaaaattat aacgttcctt ataacacact
      601 ctgttgtgtt tttaaaagaa aaacacaaaa agatactatc tataaattta tcttggtcca
      661 agatgagaaa ataagtaatt tcgaattaag cactccttct agtaagattt atgacgatgc
      721 atatagattt gaatgtcaag atctagaagc cctcctttcc gcaaataatc taaacaatat
      781 agaacatgaa aactttgttg taaacactag atttaattta gtttctgaaa aggactcaga
      841 tttgttagat ttgctgatag agcttactaa aaatctagat aagaaagaaa acattactgt
      901 actataacta gcatcggtcc atcattaagt ttggactatt agaacacttg ctattacaga
      961 aaaaggtatg ctagccacgc ttactattta ttggtatcaa acaagtatct taatttgaaa
     1021 ggaagatgat ttatggctaa tttatatata gagaacaaag gagacttgaa tgccattatt
     1081 actttaatcg tagttatggt aaaatcaata ggtaatatca caataggaat gctgtttatt
     1141 atattagcag cagtgctgat ttttatgata gttatttggt tcttaaatga aagatctaaa
     1201 gacaatcaac accgtaggga tatggagata aaatcaatag agtcaataga ttatttatcg
     1261 ataataacac taaaaaagcc acgttcctaa acgtgactta cgctgaacga tatgtgttgt
     1321 ttggtagacg aacaaatcgt tcattataaa tatatgatgg tatcctaata tagtaagcgt
     1381 ggctagcata cctttaatta ctttaccttt tacagttacc atacacattt tttgagcaga
     1441 aatcaagtaa ataaaaaaat attatatttc acaacatgct aatagactca tatctagaac
     1501 gcattaagta tttacctgtc tggttcgctg agacttcttt tttaactttc ttcaattttc
     1561 ttctttattc taaaaagcgt actgcgactg aaaccggtta tagcttcaac ttccttatac
     1621 gatttacctg aagtaagcag ttcatatgcg tgcctcttct tcggtgtgat tgttgctttc
     1681 ggacgtcctt ctctgaaatt aggattattc tttcttgcaa acatttttcc ttcttgggta
     1741 cgttccacaa tcatatcacg ttccatttct gctacactca acaacgtccg tgtcaccatt
     1801 cgccccatgg acgtattttc aatcgttcct agattcaaaa ccttgatcgt tacgttatca
     1861 tcgagtaaag gttcaatgat ctctaatgct tctctcgtgt tacgagcaaa tcgatcaagc
     1921 ttcgtaacaa ctatttcatc tccaggcttc agaccagcca acagctgatt gaattttggc
     1981 cgatcccgtt ttgtacccgt aaatttttct gaaaaaatat tcttcttctc tacgccgttc
     2041 tcaagcaact gttgaatttg ttcttttgta ctttgagaag cggttgagac acgtgcatat
     2101 ccatatttcg tcatttggtc cacctacttt tacaaatcat ctatcgtata ctcagaatac
     2161 ccttcataga aatagctgac atcgattcct ttcatatata actcgcgatc gtcaatttta
     2221 tcagtcagag cattggaaat tagatagcgt atttccaaat cgtttatggg acttcgctcc
     2281 attgcagaaa gatagtctgc tttatcgatt aagttccaat ctacaacttt ttgcaattct
     2341 tcctttaaaa tgagatccag ccaaattcta gtacttcggc catttccttc tcgaaatggg
     2401 tgagcgatat tcatctccac atatttcttg ataatctctt caaaagaagt ttgtggcatc
     2461 tgatcaatat gctgtaacga atgttctaaa tacataactg gtgcaaatcg aaaatttcct
     2521 tttgcaatat tgaccgatcg gatttttccg gcaaaatcgt aaatatccga aaatagaaat
     2581 tcatgaattt cagataaacc tttaaatgta ccaacttcga tttcatttat ttttccacaa
     2641 tcgtacaatt ctttcgcttt ttgtttactg agtttttctt caaccttagc caactcaact
     2701 tgattggtta atcccaattt attctctaaa atcatgcgaa atctccttaa ctttatgaca
     2761 taagtttatg aaacactctc aaccccatta tatcgcgatt ttgtttatgt gtcaaaaact
     2821 attaagtttc tgacccccga tagatttttc aagtgtctct attttgcaca gtctagttga
     2881 cctttgatac acctctatat ttatagagaa tctaaaacat caacatggca tactcaaaat
     2941 tctaaatatt agggataaag aattctccta tacaatcaaa aatttccttt atttcgaact
     3001 ccggtcacct aactctattg atctcttaca agccaaagaa tatctctata ctacaaagaa
     3061 acaatagggt gcctggttgg tctctttgtg ttttatttta gaatctagaa cgtaaatatt
     3121 cttgtcattc tgattttatc taagaatatc aattaaatct ttttttgcag cctctgaagc
     3181 gggcattaca gaaaagacca gtccaataac cgaagatacc ccaaccgcta gtaaaatagt
     3241 aaatagatca agtgacacgt ttacctttat caaagaacca acactataag caagagccat
     3301 tcctaataaa ta
//
LOCUS       DADVXK010000169         3301 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.175, whole genome shotgun sequence.
ACCESSION   DADVXK010000169 DADVXK010000000
VERSION     DADVXK010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.175"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(52..2523)
                     /locus_tag="KB909_002768"
     CDS             complement(52..2523)
                     /locus_tag="KB909_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6838725.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            2796..>3301
                     /locus_tag="KB909_002769"
     CDS             2796..>3301
                     /locus_tag="KB909_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838726.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
BASE COUNT          976 a          664 c          595 g         1066 t
ORIGIN      
        1 aaagatacac gagtggttgt tcttttttac tcttttttga gatacttttc gtcaattttc
       61 tcgtttaaat atcgatagaa attttttagc tacgcgacta aacggctttt gctctttttc
      121 atttttacgt tcaaacaaat attctaccaa tgtggtcaaa tgcctaaaaa tcgaatctgc
      181 cgagaaaaat agaatgctca acagcaaaag tgatacagct gagataccgg tgattgaaaa
      241 cagcttatgc aaaaagatga ccgaaaaaaa gttaccgcta gcacagaaaa gaatgatctg
      301 acttctgaat ttattcagcg gtgaacagat tttatagaga acgaggaacc ctactgcaat
      361 caaaagcatg gtagatgctg tagaaacatc tgttttattt agattcaaag tcaccccgca
      421 gatcaccaac gcaccgacta cgatcatatc tgttagtcca cctggcacag ctttttccat
      481 cacattcatg atgaatttcc ctctgattcg ctttttgttt tcttctagag caagcaagaa
      541 agatggaagt ccgatagtaa acaaactaat caatgtgatt tgtgatggtt ctaaaggata
      601 ggtcagagca aagatcactg aaaacagtga gagcaaaaag gagaaaatat tcttcactaa
      661 aaacaagctg gctgatcgct caatattgtt cacaacgcgc cgtccttctg caacaacttc
      721 tggcatgcgt gaaaagtcag aatcaagtaa gaccacttgt gaggcctgca tggcggcttc
      781 atttccggaa gccatcgcta tactgcagtc tgcttctttc atggctagaa tatcattcac
      841 gccatcacct gtcatagcta ctgtattgtt acgctttatc aattgaacga agattttctt
      901 ttgttctggc ttgacgcgtc caaaaactgt atatttttcg acagctgctt catattcttc
      961 ttctgataat ttagatgcat caacgtactg atcagcatgt gaaatccctg cttggacagc
     1021 tacattggat acggtgagcg gattatctcc agaaatcact ttgatggcta cttgctgttt
     1081 tttgaagtaa tcaaatgtgg ctcttgcttc ttttctgata ggattagcaa tcagaatata
     1141 gcctaatggt gtgactgctt ctgtcaatac tggttcttca agaatcccat cgtacacacc
     1201 aaagaccaac acgcgatagc ctttttcagc gaaagaaaca aactcttccg catattccgg
     1261 caattgatcg cgcaaaacca tttcgggcgc tcctaaaaca tacaccttgt ctgccaacgc
     1321 tacactgctg aatttttgga cagaagaaaa aggaataaca tggtgatagg attgatcagt
     1381 ggtttttgta aaatatgctt taacagcttc cattgttgca ttgtctcctg ccatcgcttt
     1441 tgcatagtca gcaatgcatg cttccaattg atctgactga ctgattattt cttgtttttt
     1501 agagacgatc attttttgaa cagacatttt attttctgtg atcgttcctg ttttatctac
     1561 acaaaggaca tttacccttg ccaatgtctc aatgcttttc atattgtgta aaagaactct
     1621 ttgctttgct agtttagtcg cacttaatgc taatgcaatc gtcgtcagca agtacagtcc
     1681 ttcaggtatc ataccgatca atgctgcttc cattgcaacg acactttctt tgatcgtgtt
     1741 tccattaaaa aagtaacttt gagaaaaaag caggataccg ataggaataa tgatgatccc
     1801 aatccatttg atcaattgat taagagaagc aatcatctcc gactgttctc cttctcccat
     1861 tgtcttggct ttgactgtca gctgggaaat atacgaatct gctccaactt tgtctaatcg
     1921 ggcgtaagct tttccggaaa caatgaaact gccggacatt aatggatcac ctatttcttt
     1981 ggttatttca tctgcttcgc ctgtcaataa agcctcatta acttgcagtt tcccttccac
     2041 gacctctgca tctgctggaa tttgatatcc agtctctaaa ataacaatgt catctattac
     2101 aaggtcttct atatctattg tttgttctat cccgtctcgt atgacattga cttttgctgt
     2161 atttaaaaca tttagttcgt ccaagatctt tttggatcga atttcctgaa aaatggcgat
     2221 tcctgtattg gctatgataa ctggtaaaaa agtcaagttc ttataggatt ctactaaaca
     2281 aagcaaaatg gctaagataa gaaagatcaa attgaaatac gtaaatatgt tttccaatac
     2341 gatttgctga tttgttttga atgtgggatc gactgaatta tttgctgcac ctttttctat
     2401 tcgttccttg acttgatctg ccgttaatcc ttctttatac gatggaaaaa gacggatgac
     2461 tttatctgat gatctttgtg ttactttctt ttttttactt cgatttatcc atttattctt
     2521 catgtggcta cctcgattga tttcgttttc tggatatttc caaacttctc ctatccagta
     2581 tagaacagat atggaaagtg ttcctcacat taagcttgca aacacctttc attcctgtca
     2641 tatagcaaaa aaaaagggtt ctataatatt ttgtgttggt ggaaaatcga aggcgatttt
     2701 ctactaacac tttttcttcg tttcaactca aaaagagact cacttttggt aaaatttagt
     2761 cgaccaaaac gtcatcctac caaaggagtc tctcaatgga taatcatact agaaaattac
     2821 tcggattaac agataaacat ttattttttg atgaagaatg gctgattgaa aaagaatata
     2881 aaggcgttca agcgcagttt attaaaggaa aattggatga ctcttcttcc tattgtgaac
     2941 actgtcgatc ggttcgtatt atccgcaacg gttcctatac gacacgcact cagatgttga
     3001 aagtcaaaga aaagttaact attttagaat taaaacgtac ccgttttctc tgccatgatt
     3061 gtggaaggac cttttctgcg aaaacggact tagttgatga acatcatcaa ctaacaaagg
     3121 aactgaagca ggtgattctc atggaactgt acgaaaatca atcacgtaaa ctaatcgcta
     3181 agaagtactt cgtctcggat gggacggtga cacggatctt gcgtgaagca acgaagcatt
     3241 accagccacg tatgaacttc cttccgacgg tgttgtgtat ggatgagttc aaatcaatga
     3301 a
//
LOCUS       DADVXK010000170         3273 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.177, whole genome shotgun sequence.
ACCESSION   DADVXK010000170 DADVXK010000000
VERSION     DADVXK010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.177"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            278..787
                     /locus_tag="KB909_002770"
     CDS             278..787
                     /locus_tag="KB909_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6838727.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="KB909_002771"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="KB909_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6838728.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..>3273
                     /locus_tag="KB909_002772"
     CDS             2322..>3273
                     /locus_tag="KB909_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6838729.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLP"
BASE COUNT         1162 a          525 c          650 g          936 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cag
//
LOCUS       DADVXK010000171         3249 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.178, whole genome shotgun sequence.
ACCESSION   DADVXK010000171 DADVXK010000000
VERSION     DADVXK010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.178"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..558)
                     /locus_tag="KB909_002773"
     CDS             complement(<1..558)
                     /locus_tag="KB909_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838730.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSIT"
     gene            complement(620..1300)
                     /locus_tag="KB909_002774"
                     /pseudo
     CDS             complement(620..1300)
                     /locus_tag="KB909_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1622..1843)
                     /locus_tag="KB909_002775"
     CDS             complement(1622..1843)
                     /locus_tag="KB909_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838731.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(1941..2186)
                     /locus_tag="KB909_002776"
     CDS             complement(1941..2186)
                     /locus_tag="KB909_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838732.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            2426..3040
                     /locus_tag="KB909_002777"
                     /pseudo
     CDS             2426..3040
                     /locus_tag="KB909_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT         1023 a          600 c          495 g         1131 t
ORIGIN      
        1 agttattgaa ctaattaata aagatagaat catcgtagtt ggatacgtag atgaaacctc
       61 aactatagtt cttttccccg tacctttaat agacactaaa ccattgtcat tttctatagt
      121 gctctttttc ccatttactt tcacaactgt tccccaataa ttgaatacag gtaatgtgat
      181 attttgctca tcggcatctt ctactgtata gactattttg gaattatatg ctttatgaga
      241 tgcattctcc caccgatcac caacttttac ttcatgtttc tttaaatgat ctttatattt
      301 caatgcatct aatggtgcat agtcatatag gcctccagtt cttgaggatg tataacgtgt
      361 aacatctttt ttggtcataa ctaaacgacc tttatacgac tgaattttat gcgaataatt
      421 tgcttctgtt gctgcagtca cagtaaaaat aataagaact attcctacaa ggctccacat
      481 actttttttg ttgcttgttt tccactttaa aaacactatg gttaagatta atgaaccaaa
      541 aagcacttga aaacccaagg ttctcggttc tgttgcgaag tttgaaaatc aaacgcgccc
      601 tctctgaact ccaaatatct taggctgtta ttcccattaa taccttgatt tcagtagaca
      661 ccgaaaagcc gaagagcgtt ccatttcttc ggttcttttt atatattcct cgaatggtct
      721 ccatgccctt aatcgtggaa gaggctgtac ggagactttg ataaaattta tttcgtcgtt
      781 taataggtcg atggtcttgt tctattaaat tgttaagata cttcacagtt cggtgctctg
      841 tcttagtata taaacccaca ctctgtaact ttctaaaggc ggagccaaga gaaggtgctt
      901 tatcggtcac aattgctttc ggctcaccaa actgtttatg gagtcgtttt aagaaagcat
      961 aggctgcttg cgtatcccgt ttctttcgta accagatatc taaggttaag ccgtccgcat
     1021 caattgcacg ataaagataa tgccaacgtc ccttaatttt gatataggtt tcgtccattt
     1081 tccatgaata gaaggattgt ctatttttct tcttccaaag ataatagagg actttgctgt
     1141 actcttatac ccaacgataa atcgtagtat gacaaacatt tattccacga tcatataaca
     1201 attcctgaac ttcacgatag cttagattgt aacgcaggta gtaaccaaca gcgacaataa
     1261 tgacgtcttt tttgaattgt ttgcctttaa aatgattcat tactctgtcc tctctgtctt
     1321 ttttctcaat tttacactaa aatagatttt ttggaaaact ttgcaacaga accgttttta
     1381 ctatatactt cttcccagaa cttgtccgtc tccttcaaat tatctctacc tctcgagttc
     1441 attgggtggt ttgcccattt attaaacatg gaatcacctt tctcatactc atatatttat
     1501 gtcctatttc aattatattt atatatgctt aaataaattt gtatcctgaa atttattgta
     1561 atatgaagct gtattttaca tatagtaacc aaagagttaa taaaataaaa agagcgaacc
     1621 attatagatc agctcttttt tcattgctgt ttttaatctt atctagaatc acttcaaatg
     1681 tttcaaaggt atttacatct aactgacata accaaagcaa gtacttcttt tctttgtaag
     1741 tccaatcaat attacggtaa gaggacatta gattatggta ccttgctctt tgttcaactg
     1801 aagccaattc ccagcgtttt tcaaatattt tttcttcttc cattattgat ccctcgcaag
     1861 acgctacctc aaacttaaat aatgggcagc gaaagtctaa ttccttagat ctaagtatag
     1921 caaacaaata tgaaaaaaac ttagaaggta gtaaaagttc ttccgtcttt tgctttgctt
     1981 ctattcttaa tgtgtttcgt tatcggtgcc ctacaaagat tttcattaat tacacactca
     2041 tttattgttg tgtattttct gacatttctc tcttgatcaa ttattttaat tccatgggca
     2101 tcctgatagt tcataggaga ggagcggcta tcagaaatag ttgcacctat ctcttgaact
     2161 tcttttacaa cttctggaaa atccatccat cctgcttcag ctgtcaaaag taataatcta
     2221 taatatttat ctttcctttt caatctaaga aatcgtcacc ccattctttt tcttctatta
     2281 taaactattt aacttttaga attcaaaaac cgtttgtcta tttagagttt accctaaata
     2341 gacaaaaata taacattgaa aaatttagag ttctaacgta tgattagggt gtattataaa
     2401 cgttatagaa aagtagggaa taaatttgaa aattgcttat attagagttt catccatcga
     2461 tcaaaatgaa caacgtcaaa ttgaagaaat gaaaaagttt ggcgctgaaa aaatttttat
     2521 cgaaaaacaa tctggagcga cgattagtca tcggccgatt ttccaggaag ctttagattt
     2581 tgtcagagag caagatattt ttattgtaga agccattgat cgacttggac gcaattatga
     2641 cgagattatc gattcagtga attatctaaa gaagaagaat gtgcgactta ttatcaccag
     2701 tttaccgatc atggctgaag caattggaaa tcctctccta gataaattca tcaaagactt
     2761 aatcatttaa atctcagcca tgattgctga acaagaacgt actgaatcga aacgacgcca
     2821 ggcacaagga attaaaatcg ctaaagcaaa cggcgtctat aaaggtcgtc ctaagttata
     2881 cagtgcagac accaaagatc ctcaacgtcg ccttgtctat aggagtatcg ttcaggatct
     2941 tgagaatggg gttgctatct caaagattgc aacagactac aatgtgacta ggcaaacaat
     3001 ttaccgaata aaaaaagaaa tcgaccaact aattgtatga tttctttttt gaatcacgta
     3061 attattaatt agctttgtca tcaatacaga caatcatttt agattcatct agctaagttg
     3121 attacattta tgttaaaaag aatttagtta acataaatat aattgatgca taaatcgtcc
     3181 ttatttaaag gcatttaaca ttgacaactt agtataatgt atcttatgta aactaataag
     3241 atttgaatt
//
LOCUS       DADVXK010000172         3172 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.179, whole genome shotgun sequence.
ACCESSION   DADVXK010000172 DADVXK010000000
VERSION     DADVXK010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.179"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            147..755
                     /locus_tag="KB909_002778"
     CDS             147..755
                     /locus_tag="KB909_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6838733.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            755..1096
                     /locus_tag="KB909_002779"
     CDS             755..1096
                     /locus_tag="KB909_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838734.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            1338..>3172
                     /locus_tag="KB909_002780"
     CDS             1338..>3172
                     /locus_tag="KB909_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBB6838735.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFV"
BASE COUNT         1095 a          424 c          684 g          969 t
ORIGIN      
        1 cacgttgtgg gacttttttt aatacgatta caatcgatga gcaaatatta tttccaaaag
       61 cctatttacc tgatgaagca gatggtgttc aacatattcg ttttacatta gaatttccac
      121 aatatattga atggagtgaa agataaatgg gagaaaaaag aagtaaaacc ggaattattt
      181 ctgtcgaaaa acctacttgg tttcctttgg aagatgagac agggaatttt ccggtatatg
      241 gtactgcgtt gccaatggga acagcagtaa gtatcaaacc aacagctaat tatgaaacaa
      301 cacaagatta tggggattca gtggttcaag atcaatttac agcttttggt ggtgcagaag
      361 ttgaactgga agcaaatgga tatactcata aagttttatc tacaattact ggagggaaaa
      421 ttgttaaagg tggtgccttg cgttctggag aagatattgc gcaagatggt gcgtttgcat
      481 atagacgtaa aaaatcgaat gggaaatacc gttatacggt cttttataaa ggacagtttg
      541 ctctagattc agatgaaaca tcaacgattg aaggaagtaa agtaagtttt actcatccaa
      601 cttggaaggg ttcatttgta gatgtaccag gacttggata tatgtattca gttgatgaag
      661 atgatgaagg cgtggataaa gcaatgatcg gaaattggtt tacaaaagta gcaattccaa
      721 ttgaagaagc agaactttca ggaggtacag aataatgtca aaatatcaaa caacgattaa
      781 attaacgaaa aaagatgaag aaggtaaata tgagcaagta caatttaaat ctgctgaatt
      841 tctaccaggc ccagtcgtag aagaagcagc agaagtaatg gagggaatgc aaaatgctgt
      901 agatggaaaa tcagtatcag aagcattaag tcgagcttat tcatttattg cagatatttt
      961 gtttgaagga cagtttactg gtgaagatta tcgtcaaggg atcgatgctc gagaaattgc
     1021 ttcgttgaca ggtaagttat taaaatctgt tactgcaggc tttgatgaaa cttatacaga
     1081 aacgaaaaaa aagtaagcga agctctcaaa tatccttttt ttaaacattc gattacttat
     1141 cgagaattag atttaaagac gcaattactc gaagcaggtt ggacgttacc agaaattgaa
     1201 cgtactgact ttgacgagtt aatgcgtctt tttgcttttc gagatgcagt aaaagagcat
     1261 gaggatgttg agtactacga taacttcacc caattttagg aggtgatact ttgaataacg
     1321 atgacctaat tctgaagatg atactagatg aatctggttt tactgccggt atgaataatg
     1381 ctgtcaaaaa gttgaactct tttgatgaaa caatcgaaag aaaaagtaga aatagtggca
     1441 gttcattagg tagtatttgg aaaatatttg ctggaagttt tctagctagc ggagtaacta
     1501 gaatcgtagg agctggcttt gatctaatca agggttccat aagtggagcg gttgatcgag
     1561 tagatacgat gaataacgct ctacgaaatt tccaaaatat gggatttagt aattcagaaa
     1621 ttatgaagaa tatcggaaag aatgggcttt tatctcaagg tattcaagga cttcctactg
     1681 ctttgaatga tgcgataagt catgttcaac ttcttgcttc ttctacaggt gatttaactc
     1741 gttcaactca aatatttaaa gctttaaatg atggaattct tggtttcggt ggttcaactg
     1801 atcaagttaa tgaagctgtt attcaattat ctcaaagttt ctcaaacgga aaagtagacg
     1861 cacaaacttg gaactcaatg atcaacgctc aacttggacc tactctttct gctattgcta
     1921 aaaagatggg aattacaatg ggagatctga aagaaggttt atctcaaggt aagatttctg
     1981 ttgaagaatt ccaaaatcaa ttaatagaaa tggataccaa aggtggcgga ggacttaaat
     2041 cattaagtca aatcgctaaa gattctacta agggaattaa aacctctata caaaatgcaa
     2101 aaacagctgt tacacgtggt gttggtgagg taatagaagg attaaataaa gcattagtag
     2161 attcagattt aggtggattt aagggaatta ttgataaagt gggcagttca atggaatcgt
     2221 tcttaaaagt aattgctgca aatattccta cagcagtatc atttttaagt aatttattta
     2281 acgaaattca aaaatttggt tctgctttga aattcatgat gccctttctt gttcctgcag
     2341 ctaccgcttt tggagcgttc atgtttcaac ttaaaggtat accagcaata ataaaaagct
     2401 tcaataattt taagaatgcc ataattggcg ttggaaattc attaaagatt atgggggcaa
     2461 tagctgctgc taattcattt gttttaatta ttggtgcagt cgttggtgca atagctgttt
     2521 tcggttactt tatggcaacc aatgaagagc ttagaaacaa ggttatatct atttggaatg
     2581 atgtgaaaga ttccgtaatt ggtgtattaa aaaatataaa ggactgggga attgatactt
     2641 ggaattctgc taaagaaatg gcatcaaatg cagttgaggg tgtcaaagat gcttggtcag
     2701 gaacaaagga atggttttct aacacctgga aaggtattaa ggatggggcc acaggtttat
     2761 ttgataaaac agtagagact tcaagaaatg cagtcgatag tgtaaaaaat gcatggtcta
     2821 atatgaagaa atggttttct gatacttggc aaagtataaa agattcagcc agagaaaaat
     2881 ggaatggaat caaaggttct attatgtcag ttgctggtcc attgattaca ggtataaaga
     2941 atgcattttt acatgttact ttttatctag agaccttatg gaataattta gttgagattg
     3001 gtaaaaacgt ctttgagatt ttaaaaaatg ttatacttgc gccggttttg tttattacct
     3061 ccatgatttc tggtggatgg gaagaaacaa aaaataatat gattgctgtt tggaataata
     3121 ttaaagaaag tgccataaat atttgggaat ctataaagaa tatatttgta ag
//
LOCUS       DADVXK010000173         3093 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.180, whole genome shotgun sequence.
ACCESSION   DADVXK010000173 DADVXK010000000
VERSION     DADVXK010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.180"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..520
                     /locus_tag="KB909_002781"
     CDS             <1..520
                     /locus_tag="KB909_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBB6838736.1"
                     /translation="NGSSSVNTFIVNNEKELLFFSEYIDNPLIQEYILGEEYTIDVCL
                     NFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKKMLEKLNAIGHITIQCIKNE
                     KGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKNLRYRENYLDKMIALRYDQA
                     IYLDEKGNVYND"
     gene            492..1208
                     /locus_tag="KB909_002782"
     CDS             492..1208
                     /locus_tag="KB909_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6838737.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            1205..2323
                     /locus_tag="KB909_002783"
     CDS             1205..2323
                     /locus_tag="KB909_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBB6838738.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            2313..2933
                     /locus_tag="KB909_002784"
     CDS             2313..2933
                     /locus_tag="KB909_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6838739.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
BASE COUNT         1183 a          375 c          591 g          944 t
ORIGIN      
        1 gaatggtagt tcatctgtta acacatttat tgtaaataat gaaaaagaat tgttgttttt
       61 tagtgaatat atagataatc ctcttattca agagtatatt ttaggtgaag aatatactat
      121 agatgtttgc ttaaactttg attcgacacc agtaagtatt gttcctagaa aaagaatagc
      181 aactagaggt ggggaaatac tgaagggtca gattattaaa gatagagaac taattgagac
      241 tacgaaaaag atgttggaaa aattaaatgc aatcggacat attactattc aatgtataaa
      301 aaacgaaaag ggaatatttt atttagaaat aaatgcaaga tacggtggag gagcccccat
      361 tagcattaaa tcaggagcta attcccctga atatattata aagatgatag attcaaaaaa
      421 aaatttgaga tacagagaaa attatttaga taaaatgata gcactgagat atgatcaagc
      481 gatttattta gatgaaaaag gaaatgtata taatgattaa agcggtgatc tttgatttag
      541 atgacactct tgtgtctgaa tatgattatg taaaaagtgg atacaaatgt gtagctagaa
      601 gattagcagt gcaaaaaatt ttcccggcta cttttgacga aatatataga gtccttttag
      661 atctttttgc tgaagatagt aaaaatgtat ttaatcgtct atatgactat tttgaaattc
      721 cttatagtaa aaaagaaatt aaagaactgg taaatgtata tcgagaacac aaaccagaca
      781 taaatttttt agaaaatgca gatactttat taacggaatt aagaagtaga ggatacaagc
      841 tggggattat tacagatggg tatgctataa cccaacgaaa caaattggat gctttgaaag
      901 tagactattt ggtagattat atttgtatta ctgacgaatt aggccgtgaa ttgtggaaac
      961 cacaccctat ctcatatctt ttattgttag aaaagtttaa tttaaaggca caagagtgta
     1021 tatatattgg cgataatgag ttgaaagatt ttataactgc caaatcaata ggaatgcaaa
     1081 caattaaaat agaaagagta aatggtattt acagagaaag cagtttgaag ttcaaaagat
     1141 tttaccaagc tgataaaaaa atacgttcgt tatgggagat aaaaaatttt ttgggagtga
     1201 tttcatgaaa agtaaaagaa ttctattagc ttctccacat atgagtgaag aaggatatga
     1261 aaaagagtat gtaaaagaag catttgatac aaattgggtt gctcctttag gtgcgaatgt
     1321 gaatggattt gagaaagaat tagcagaata cgtgggagct agtcatgctg ccgcattatc
     1381 ttctggaaca gcagctatac atttagcttt gaaagcggct ggggtcggta aagatgacat
     1441 agtgatttgt cagtccttga cgttctcagc tactgctaat ccaattctct atcaaggagc
     1501 tatacctgta tttgttgata gtgattacga aacttggaat atgaaacctg aacatttgcg
     1561 aacagcacta gaaaaatatc ctaacacaaa ggctgtatta gtagtacatt tgtacggttt
     1621 atcagctaat ttagacgaaa ttactaaaat atgcaaagaa tacgatgtta ctctaattga
     1681 agatgctgca gaatcattag gaacaacata taaaggaaaa tatactggta catttggcga
     1741 ctatggaatt tattctttta atggaaataa gataatcaca acttcaggtg gcggaatgct
     1801 tgtatccaat gacaaagaaa aggtggaaaa agtgagattt tgggctacgc aatctcgtga
     1861 gaaggcacgc cattatcaac acaatgaaat tggctataat tatcgaatga gcaatatcgt
     1921 tgctggtatc ggtcgaggac aattgaaagt attaaatgaa agaattgaga aaaaacgata
     1981 tattcatagt ttttataaaa aagaattgtc taaattgtca aatatacaat tcatgccaga
     2041 aaataattgg aatgaaccga attattggtt aagtgtcata acaataaagg gaataaatgc
     2101 gaatcatctt attgatgagt tagacaaaaa taatatagaa gcccgcccag tatggaaacc
     2161 tatgcattta caacctgttt ttaaaaatta tgattatatt ggcgatgatg tagcagaaac
     2221 tttatttgac ttaggagtat gtttaccatc agatacaaag atgacagatg aagatttaaa
     2281 atatgtagta tctacgatta aaagagtgat caatgatgcg taaaaaaact ttctatcagc
     2341 tttttgggaa aagaatttta gatatcctat tgtcaggaat tgctctcatc gttttatcgc
     2401 cgataatctt aattgtaggt tttttagtaa gaattaaact tggttctcca attatcttca
     2461 aacaagaacg accaggaaaa agtgaaaaaa ttttttccat gtataaattt cgtacaatga
     2521 ctgacgaaag agaccacaat ggagaatatt tacctgatga aattcgacta actaaatttg
     2581 ggaaaatgct tagagcaaca agtctggatg agctacccga actttggaat attttgaaag
     2641 gtgatatgtc gatcgtagga cctcgtccat tattagtgga gtatttgcca ctatatagtg
     2701 agaagcaacg gaaaagacac aacgtaagac caggattaac tggactggct caggtcaatg
     2761 gaagaaatgc tattagttgg gaagaaaagt ttgatttaga tgtttattat gttgataaaa
     2821 ttagtttctt taatgatctt attattataa ttcagacatg taaaaaagta atcaagaaag
     2881 agaatattaa tacaatcaat aacaatatcc cagaaaaatt taaagggagt taaatacagc
     2941 agcttaatgc aagttttgtg acttgcatta tatttaggta taaatcaaag cgagtatatt
     3001 agaattatat aacatatgtt aaaaaaacgt atagctaata aaagtatgat tttaaaaatt
     3061 tgtgtagagt tttaaatata ctgtttcaat acg
//
LOCUS       DADVXK010000174         3075 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.181, whole genome shotgun sequence.
ACCESSION   DADVXK010000174 DADVXK010000000
VERSION     DADVXK010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.181"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(260..1429)
                     /locus_tag="KB909_002785"
     CDS             complement(260..1429)
                     /locus_tag="KB909_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBB6838740.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            complement(1500..2050)
                     /locus_tag="KB909_002786"
                     /pseudo
     CDS             complement(1500..2050)
                     /locus_tag="KB909_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            complement(2253..2732)
                     /gene="rlmH"
                     /locus_tag="KB909_002787"
     CDS             complement(2253..2732)
                     /gene="rlmH"
                     /locus_tag="KB909_002787"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBB6838741.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT          943 a          533 c          425 g         1174 t
ORIGIN      
        1 ttagacgggc agttatccgt agaagttctt agaatagcta atttacataa ttaaattata
       61 tgaaatttaa gtttgaacaa tatactaaga actcccctta ctataaagtg aaataaatta
      121 gcatatgaat aaccgtgcta ccaagctttt cattaataaa atatttttat taatatttta
      181 taactttacg caagatcata attttgtcgg gagcgtcaat aattttgtgt aaatggaaaa
      241 gcccattctg ttgatcaagt taaaacattg attctaatgt atcatgtatt tctttaaaac
      301 ctttatgaac tcggcataga aacttttgat tatagttgtt gaattgagat actagaaatc
      361 tctccagaga ttcttcatta ggaaattgct cttttctttt ggtatatttc tttaattgtt
      421 tgttaaaacc ttcaatcaaa ttagttgaat aaatagttct tctgattgac ggagggaaat
      481 tataaaaggt taatatagca ggattcatga gcaatttaac cactcgtgga tactgctttt
      541 tccatttatc tatcataaac cttatttgat tatttgcttc ttcttttgaa cttgcttggt
      601 aaactaattt gaaatcgcta cagatttctt gtcgatcact aacacgaacc ttatgagcga
      661 tatttctaga tatatggaca caacattgtt gaaattgagc atttggataa acactatgaa
      721 tactatcgtc aataccactt aaaccatctg ttacgactaa caaaacctct tctaaaccac
      781 ggtcttttag atcttgaaga atctctttcc aaacataagc agattcagtt ggagctatag
      841 taaatcctag aacctcttta gttccatcca acctgatacc aattactata tagacagctt
      901 cttttgatac ggtttgtctt tttaagggaa tatgagtagc atccataaaa atgactgagt
      961 atttagcttc taaagttctt tctttaaatg ccgaaacatc ttcagacaca attttactca
     1021 tatttgaaat agtttgtggt ttgtaataat gaccatacat tttttcgatt agatcagaga
     1081 tttcggacat agtaattcct ttttgaacta gctgaataat agtggtttct aaagagtcat
     1141 tggttctttt ataagcaggt aaagtttgtt gagaaaagtc tccattccta tctctaggta
     1201 ttactaaatt caattcaccg tactctgttt taaaagagcg cgaataattc ccattacggg
     1261 aattacctga attaaatcca gctctatcat acttttcata gtcaagaaat accgttaatt
     1321 cagcttgtaa taaagcgtta atagccaatt ctaggtgacg acgaaacaaa tcatccaaat
     1381 cacctttatt gattagtatt tccataattt ctgtagtaaa atcgttcata tggaagtcct
     1441 cttttctgtg aatgtgttgt ggtaactcta ttctacagaa gggacttcct tttttctatt
     1501 tacacaaaat attttacact ctcttcaacg atattcttgt aagtaattat gccccaacta
     1561 ggatttgtgg gttcatttcc atctggagtt aaaaaaacaa aaattttttt atagttagaa
     1621 taattgcgtt ctatatatat ttggtattta ttaagttgcc ctccagactc cgaagacaga
     1681 attttatttt cgatgcacac cactatttta tttttttccg ataccaataa aatatcaata
     1741 ttcttatttt ctctgtaaac aattaaatct tcatagctat taagtaaagc atcaaaataa
     1801 ttgatagcag ctttggtatc atcattagaa tctatatacc ttttcaaaaa cattttaaaa
     1861 aactcatcag ataaattgtg ggtttcattt ggagcaaaca aaaaagctaa aaaattacta
     1921 tgtcttattt catttttaga tagcttaagt atctgaaata tatttgtttt cccagtccat
     1981 ttagatagtt ttcttcaata tcatccatat cctctaatag attttttaaa cacttttttt
     2041 catctatcat gttttttctc cttgccatta ttctaactaa aattttacgt atttgtttct
     2101 atgtctacat tatcttttta acagtatcta tttttctttt gcaacttact tggctaccaa
     2161 agcaaataaa aaagttattt ataaatttct ccctaccact acctattgct attatttaaa
     2221 atagggataa ttttttctct taaaaaatat cattatttgt ggtatggagc ccccgcattg
     2281 atccggaagg cacggtagat ttgctcgaca aggatcagac gcatcaattg atgtggatac
     2341 gtcatttttc caaaagagat ctgagcattg cttcttttca tgacggcttc gctgagtcct
     2401 aaagagccgc cgataacaaa aacaaggtgg ctttttcctt ggatacctaa ttggtcgatt
     2461 tgtttagcaa aagattcact tgtaggattt ttcccttcaa ttgctaaggc atagacgtat
     2521 tcttgttctt tgattttcgc taagatccgt tccccttctt tttcttttac ttgtctcatt
     2581 tgcgcttcgc ttaaattctc cggggctttt tcgtcaggaa cttcgatcaa ttcgattttt
     2641 gcataggcat tcagccgttt gacatactca ttgatacctt ggatcaggta tttttctttt
     2701 aattttccta ctgagataat tttgatattc atgttttctc tcctttggtc ttcatgctca
     2761 ctttgtttat tataatcaat tttttcgtct atatgtttat tttggctatt tttgttaaaa
     2821 agatttcccc aacagttatg cacaacatcc acaggtttat ccacagaaaa cagtgttatt
     2881 ttaccttatt tcatcacatt cattaggcaa acatacgttt tataagaatt tatccacttt
     2941 atacacaggc tgtggatatg ttttatccct tatttttcca atcctatccg cgtagtttta
     3001 cacagtatct gtggaaaaag aaaatcaaat attttcatct gaaaacaatg atttttccta
     3061 aagtttttca taaaa
//
LOCUS       DADVXK010000175         3047 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.182, whole genome shotgun sequence.
ACCESSION   DADVXK010000175 DADVXK010000000
VERSION     DADVXK010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.182"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(221..1414)
                     /locus_tag="KB909_002788"
     CDS             complement(221..1414)
                     /locus_tag="KB909_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6838742.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(1498..1698)
                     /locus_tag="KB909_002789"
     CDS             complement(1498..1698)
                     /locus_tag="KB909_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBB6838743.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(2122..2355)
                     /locus_tag="KB909_002790"
     CDS             complement(2122..2355)
                     /locus_tag="KB909_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838744.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(2362..2793)
                     /locus_tag="KB909_002791"
     CDS             complement(2362..2793)
                     /locus_tag="KB909_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6838745.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT          675 a          808 c          704 g          860 t
ORIGIN      
        1 tctctcttga tcaaaaaaat cctcagaatc gacaaaattt tcctttaaaa ttatatggga
       61 ttttagatta tctttttaga agttcttgaa tgtcggtata gcccgtgttt ccgggctttt
      121 ccggcatttt tgatattgtt agatacttac aaatgttctt attacctctc accatttccc
      181 cctcaaaagt agtaaatgga gtagtaaaac cggccttgtg tcaggctgcc agccgttcca
      241 tttctgccct tgcggaatcg aatgtggcgt gtgcataata gttcagcgtc atggtgatat
      301 tggaatgtcc cataatgtac tgcaaggctt tggggttcat tcccgcattg gctaaccggg
      361 tgcagaatgt atgacgcata gcatggggcg tcgtcgtttt cggcaacgct tcttcatggc
      421 tcttgttgta cttcttcaca agcctgccaa acatcccgcc ataatctacc gccgtcatgg
      481 gatagccgtt ctgtttgaga aacaggaaat tggcataccc gtcaataatg aacggctttg
      541 cacctttgcg gttttttatc actcgctgga acgcctgata cacttcctca ttcatgggga
      601 tttttctgac gccgctttgg gtcttgggtt cgtcaatata gtaaccgacg ccggtatttc
      661 tcaaaagctg gtggctcacg atgattaccc ggttttcaaa atccaaatct ttgtccgtca
      721 gtccgcacag ttccgaaatg cgaagccctg tccccagcag aataacgatt gcgtcataat
      781 gcttttggta aaccttatca ccttgaataa aggacagaaa actttcttcc tgtgctggtg
      841 taagaggcac ctttggttcc gtatcgtcgt ccagaacgtc actaagctgg aagtcaaacg
      901 ggttttttcg gatgcaatcg tcctgtatgg cggtgtaaaa agccgctttc agggaacgct
      961 tgtcgttatt gatggtctta taagaaaggc ccttttcttt catccgaagc gcccattcct
     1021 ttgcgtcgga cagcttcaca ctgtcaatcg ggcagctccc cagccgatct tgttccagaa
     1081 tacgcatcag ccgttcccgg cccagtttgg tgttgtgctt cacattgccc cggtgcctga
     1141 tctgcttggc gtagagctgg cagacggtca ttttcttgcc gatggtgtct atcccgtcgt
     1201 caaggtcttt ctggatttct ttctcctttt cccggagtga aatatcctcc cgtttacctg
     1261 ccggggtctt atccgtaggc actaacttcc atgagtaaac aaactgcggt tttccaaagg
     1321 tatcaacata tttgtaagca tatcgtccgt cttttctctg gctctctcca gaccgcaaaa
     1381 cgcgattttt gctgtctcgt cttttttctg acatctcgtc atgctccttt ccatgacgga
     1441 aagagccgca tatatgctta taaattatta taacatatct gcggcccttt ttcactatta
     1501 gattgtgtcc aaagtgtcaa ttattttctc aaactgcttg cgtttgatct ggatgcggtt
     1561 gccattcata atgacccagc cagaggccgg attttcctcg gccagcttac gcaatttgtt
     1621 ttctccgata cggaaatatt tagacgcttc ctcaatcgtc agcgtgtatt tttcccaaat
     1681 aggcacatca tggttcataa tgcagccccc tttcacaaat tcaaaggttt gtgtgattta
     1741 ggggcataga cggacggctg ctggcacagc tccacgggac tttcaccccc gcgtggttct
     1801 cacgcggccc tacccattgc ctgcgacgct tttaacgctc ggactgtggc tataagggag
     1861 tatcatagtc ctgcctgtac gtcgtcgccc gcaagccgcc acgctcacat tgcggcgtgg
     1921 tgttcctcgc tccgcttttc ccgtagggaa aagtatcatg gcgcaccagc cgtccggctc
     1981 ggcacagaca gaatgtgtcc gtatgcccta tgatgcgccg ccgttatctt gcgggcatat
     2041 ttatcaaggt gcgatcaggc caccgggaaa acaccgaaac ggggaaaggg taagccgttt
     2101 catgctgccg gggccggttc gtcagttcgt gacgatagcg tggatgagct tgatttccag
     2161 acggcgcttc atggcctcgt ccagacacac atgcggatag ccgttttcgt catagagcgt
     2221 ccgggtacac agcttgttca tgtaaccgct gtaatactgc aaaacgcgct ctacggctcc
     2281 ggcatcccca gcgcgggcgg cctcgatcac cgaaaggggc aaaagctcaa tgcccttgta
     2341 gttcgggttc ttcatccgcg tctaacctcc cttcggcatc aacgccttta gctgtttccg
     2401 cagctccgat aaggtatttg tcctgtgccg ctgaacggca ctccgggaca ttcccacaag
     2461 gccgccgatc tcaccatctg ccatatccag aacacagtgc aggattaaaa tactctgctc
     2521 catgctgggc agcgcggcaa aggcttcggc aacaagctca ttgttgatat gtaggtcata
     2581 gccatgcgac gaaaacgtaa agctgtcgct ggggtagtga tctactgtac agagcttgtc
     2641 caaatctgcc tgtgacaaag agcttagtga cacttcacgg tcacggcggc gcttcatttc
     2701 agccaagtag cttttggcct cgttacgcag taccgtcttg caaaaagcat cgaacatgca
     2761 ccgcgcttca tagtcgcggg ggatagcatc catcttctca ccccctttct gtgggggact
     2821 taggtggttc tctccctttc cgctaacaag actttgacaa ggccgccagc tacccgctaa
     2881 atacctcctt tttgaaaatt tctcaaaaaa tttttttggg gacagccggg ccgcaaaaga
     2941 cgacaaaaat cgcccggcag gtcgcaaacc taccgggcga gaaaatgctt tgctatgctg
     3001 ctgatttaca tggtatagta catactcata accggaatag ccctgtg
//
LOCUS       DADVXK010000176         3017 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.183, whole genome shotgun sequence.
ACCESSION   DADVXK010000176 DADVXK010000000
VERSION     DADVXK010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.183"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..866)
                     /gene="wzy"
                     /locus_tag="KB909_002792"
     CDS             complement(<1..866)
                     /gene="wzy"
                     /locus_tag="KB909_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBB6838746.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLT"
     gene            complement(909..1988)
                     /locus_tag="KB909_002793"
     CDS             complement(909..1988)
                     /locus_tag="KB909_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6838747.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            complement(2002..2997)
                     /locus_tag="KB909_002794"
     CDS             complement(2002..2997)
                     /locus_tag="KB909_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6838748.1"
                     /translation="MDECINSLINQTLKDIEIILLNDGSTDNTLAILKKYEKLDSRIK
                     VYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFESLYNCAIAENADIAIGEV
                     GIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNRLYSHNACDKIYRRSLVL
                     EFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYRQQNNSIMHKPKSNLVFR
                     HGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQKNVGGTCEDYKNALVSLK
                     HHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKMYKTAYNMLWRIYNR"
BASE COUNT          999 a          562 c          321 g         1135 t
ORIGIN      
        1 aaagtaagtt tacttagtcc tccaccatca cgtgctttcg ttattacgtt tagaatatat
       61 attcctataa cagctaaaat aagccacttt attaattttt tataattaaa ggttccttta
      121 tattgagtgt atgcccatat gagtataata gagctataca accaacttcc tctgtctcct
      181 gacataattc ctaataaaga atataaagca aaaataataa aaacaaatct cgttattact
      241 tttgaaaagt tgctaccaat taataaacat attaaggctg gaaaaaaaag atatagaata
      301 atttgtaaat atccactttg tgtagcataa tcaccataat ataatgcatt ataaccatgg
      361 actaatgcta tacgtacctc tagtaattta gaaacaaaaa ctatcggtac tactattata
      421 gaaatgatac accctatttt aaataaaaac tttctatcgg catcagcatc tccagattca
      481 taccaactaa cttttcttag tgtggttttt ctcgtaaata agagtgctcc tatgtgaaat
      541 acaaacatag aaatacaaga ataccatttt accattatca tatctgattc actaggaata
      601 atccccgtac cataagctac tactgttgta ccgattccac gatctgttcc aataccgaat
      661 gcccacataa tgcattgccc ataactaaat aataaaaaaa gagtgaaaaa aatcgtgtat
      721 aatgaaaata ttgaatctcc ttttctccaa tgccatgtac agattgcata taagtaaatc
      781 aatattccaa gccaatttag ccaatagttc tgatttaatg aaaaagcgca aaatattgta
      841 aacgcgacta acgttaacga aaacatcaat atatttattt tttctttcac acaatatcct
      901 ccttttggtt aaaagaactg gtttaaatat tcgtaccata tatttgaaat atttttagat
      961 gtcagttctt ttcttagttt aattcctttt tgcgcttttc ttaccacact ttctctatcc
     1021 aaaagtaccc tacgcattgc atctgttaac ttatctagat tattacattc aacaagatga
     1081 cctatttcat ttctatcacc taaatacatt cttgcgccac ctactggaca atctgtagcg
     1141 ataactggca ctccaatagc cagtgcttct aacatagaat tagatatacc ttcataatca
     1201 gaagaaatta caaatcctgc cgcattttgc atcttttcat gtattttatt tgtaaattct
     1261 tttagatgaa caaattctgt taatccatta tggttgatat aactttcaag ctcggttttt
     1321 aatccccctt ctccataaat atccagttca cactcatatc cttcatgaat aagttttcct
     1381 attgcatcaa tcattaaggg caaatttttt tgtttatcca atctacatgc agtaataaat
     1441 tttttactac ttgtagtttt attataataa ggtaaatttt cctttattgg gttgggaatt
     1501 ataattgttt ttactttttt atcattgatc ttactaaaat atttttttgc gtctggtgtt
     1561 tgaaaaacaa ttccatctac atttttataa agaaaatctc taattttcct aatccatggt
     1621 tcttctggat tccgttgtgg atcatttcgt tcagaaacaa ttaatttttg ttttactcct
     1681 aacaatgaaa taatgacatg gatatttaca tcagcaagga acgaaataac cagatcaggc
     1741 tgtatttccc ttattttttt cctaagttcc ttaaagcgtt ccaaaggtct aaatgcacga
     1801 aacgaacttt tacatattat tggatgtacc tgtatttttc tattcagttc atagtcttgc
     1861 cgattcccat atatagttat aatatcaatt tcccagttat cttgaataaa attatttgcc
     1921 aaattcgcaa ttactcgttc tgcccctcct tttcccataa ttcctatcac aaaggtcaat
     1981 ttcctcatat ttcctacctc tttatcgatt atatattctc cagagcatat tatacgctgt
     2041 tttatacatt ttaaaattaa acattatact aatggtcaca agggctaact tctttctcat
     2101 attaggttca agttcatatg ctttcattct aactatattt gaaatatttt ctctcaatat
     2161 tttatgatgt ttcaaagaaa ctaatgcatt cttataatct tcacatgttc caccaacgtt
     2221 tttttgatta aaaatctcca taattagtac atcaaatgca accaacatac aagctttttt
     2281 atctattatg ttgtttccat tttgccttat caacttttca taatcagcaa tcatatttcc
     2341 atgtctaaaa accaaattac tttttggctt atgcattata gaattatttt gttggcgata
     2401 ataataacac aatttatcta cgaaacagat tcttgtattt gtcataaata cttgtaattg
     2461 aaaccaatta tcttctgcaa aaattatttt gttatcacca aatgataaat taaactctaa
     2521 tactaaacta cgtctatata tcttatcaca agcattatgt gaatataaac gattgaaata
     2581 gaattgctta aaaaattctt tcttgttata tgttgctaat tcaattgttt ttaagttcgt
     2641 tagacttttt cttattttta ctctttctat ttctctatca gaaaaaatgc ctacttctcc
     2701 aattgcaatg tccgcattct ctgcaattgc acaattatat aaactttcaa acatagtatt
     2761 ggaaacaaaa tcatcagaat ccacaaaagc caaaaattct ccattagcta ttttgatccc
     2821 tcgatttcta gttggcccta accccatatt tttatgttcg taaactttta ttctagaatc
     2881 aagcttttca tatttcttta atatcgccaa cgtattatct gttgaaccat cgtttaacaa
     2941 aataatctca atatctttca atgtttgatt tatcaaacta tttatacact catcaatata
     3001 tttttcaaca ttataac
//
LOCUS       DADVXK010000177         3016 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.184, whole genome shotgun sequence.
ACCESSION   DADVXK010000177 DADVXK010000000
VERSION     DADVXK010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.184"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            326..1651
                     /locus_tag="KB909_002795"
     CDS             326..1651
                     /locus_tag="KB909_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6838749.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1644..1994
                     /locus_tag="KB909_002796"
     CDS             1644..1994
                     /locus_tag="KB909_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838750.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1991..2161
                     /locus_tag="KB909_002797"
     CDS             1991..2161
                     /locus_tag="KB909_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838751.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
BASE COUNT         1074 a          470 c          559 g          913 t
ORIGIN      
        1 acttctacat acaactatta caaaactatt aagaaactga atactcctat tttttgtttt
       61 taaggaaagt tttttctttt ttgaatttct tatttttttc taatataact aagcaaaact
      121 ggataatacg acacttattt tcaaattttc acaagactaa tagtaaatat ccatttaata
      181 aagtgataca atgtgttgat tttacaaatc aacagaagaa gtagggaaat aacttaccta
      241 tgcttctttt tttgtacatt taatcgattc ttctttacaa aaacgaacgt atgtttgtat
      301 aatgtggaag aatggagtgt tatttatgat ggattattca aaagagccag taaatgatta
      361 ctttttgatc gatatgaaaa gcttttacgc aagtgtcgaa tgtatagaaa ggaatttaga
      421 tccattaacg actgaattag tcgtcatgag tcgagcggat aatacaggat cagggttgat
      481 tttagcttct tcaccagctg caaagaagaa gtacggtatt tctaatgtca gtcgaccacg
      541 agatctaccg caaccttttc ctaaaacgtt acatgtcgtt ccaccacgca tgaatctcta
      601 tattaagcga aatatgcagg taaacaatat tttcagaagg tatgtagcag acgaagattt
      661 attgatttac tcgatcgatg aatcgatctt aaaagtgacc agatcaatga atctttttac
      721 gactgaagga acaagaagtc aacggagaaa gaagctggct caaatgatcc aggagaatat
      781 taaagaagag ctaggattgc ttgctacagt aggtgtcgga gataatccct tattagctaa
      841 acttgcttta gacaatgaag caaaacataa tgatggattc cttgctgaat ggacgtatca
      901 aaatgttcct gataaagtat ggaatattcc tgaaatgaca gacctttggg gtattggatc
      961 tcgaatgaaa aaaagactca accaaattgg tatcatgagt attaaagact tagctaattg
     1021 gaatccatac actattaaga gccatttagg tgtgattggc ttacagctgt attttcatgc
     1081 gaacgggatc gatcgaacag atatagcgat cccaccagaa ccgacaaagg aaaaatcata
     1141 tggtaattca caagtgttac cacgagatta taccaggaga aatgaaatcg aactggtggt
     1201 aaaagaaatg gcggaacaag tagctattcg tatcaggcaa cataactgta aaacaggttg
     1261 tgtccattta tacattggca cgtcgatctt agaaacgaga ccaggttttt cacaccagat
     1321 gaagatccct ataacagata atacaaagga attgcagaat tactgtcttt tcttgtttga
     1381 taagtattat gaaggacaag aagtaaggca cgttggaata acctatagca agcttgtgta
     1441 cactgattcg cttcagctgg atttatttag tgatccacaa aagcaaattg acgaagaaaa
     1501 tttagataaa attattgaca agattcggca aaaatatggt tttacgtcga ttgtacatgc
     1561 ttcttctatg ttagaaggcg ctcgtagtat tactagaagt acattggttg gtggccatgc
     1621 aggcggcgca ggagggctta aaaatgattg attataatga tcgtggacgt ttaaagtggg
     1681 caggttttta tttatctgat catactgaaa aaattgatgc cgacaatgaa caacgagcca
     1741 atcaaaattt ggcaaaagaa caaatgacga ctgaagaggt tgcggaagta ttgaacgctg
     1801 cagtcataaa aaatagatca gtatgtattc aaaaagaaga acgaaacgct gaaggatact
     1861 atccagaaga tattgttagc aagatcttag gtagtgatga gctggggatc tacgttggaa
     1921 aaaacaaagt tcactacgac gaaatacgtc atatcgaatt ttaccaggat aataaatggg
     1981 gtcgattaga atgaacatta tccagcaata tgagctaaag tatataacct ttgatcagct
     2041 atcagaagag atttggggtt atggccagcg tttgataaat gaggttggtg ttgaacgctt
     2101 ctctttctat gtagaagctg cagcaggata ccataaatac gaatactata ttggctatta
     2161 aagtgcaata aaattatatt tcttttatgt tttacatttt gtatcaattc tgataaaatt
     2221 acctataggt aattaaaaaa tataaaaaaa ctagttacaa ccttaggacg ttgtaactag
     2281 cttgaagcat actagagcta actaaaatag cactagaaag caatgttaaa cccgtccaac
     2341 aaacttgatt taacattgag accagcttat tcagctaaat atagttgaat aagcttcttt
     2401 tgttttaaaa aaacaaaagg tgtactacga ataacgcaag taaaagaaat actattacaa
     2461 ccagtaggct acaagtaagt attactaaac attgcgtagt tagaaccttt gctctattgt
     2521 ctaaagccac aaaattagag atcagcttta tgatgctaag agcgagctgc atccatgcgg
     2581 acataggttc ttttgacact attaattctc ctttttagga taagggaaat tgctagtagt
     2641 tttttcatta gcaccatccc ccttcatttg attgagtcta gtgctgctgt gatagtttgc
     2701 tgtttaatat gcttacattc ttattataac ataaatgaaa caaacacatg gttagaggtc
     2761 gtatcaatca aaatagtgtc tcacaaacga tttattactt actcctgctg actaacggac
     2821 tgttcttcag taactgtaac tatatgtttg ttaaaaccac cattacctgt agataaaaac
     2881 caatatattt actatactca ctatattaaa tatatttagt atagtaaaaa ctagaaacaa
     2941 taaaatttgt gaatgttgta tacccccaaa caatacacat attttgaagg attaggatta
     3001 ataaagctaa aaatat
//
LOCUS       DADVXK010000178         2897 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.185, whole genome shotgun sequence.
ACCESSION   DADVXK010000178 DADVXK010000000
VERSION     DADVXK010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.185"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            7..1854
                     /locus_tag="KB909_002798"
     CDS             7..1854
                     /locus_tag="KB909_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838752.1"
                     /translation="MFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKDNSSILKI
                     ELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRIKGLSS
                     IFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNICTILI
                     SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAYGLI
                     FNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVVNLV
                     KAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITTYTM
                     GLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQFPWR
                     ILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQSKHG
                     HIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAADNNI
                     TYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEITTKY
                     TPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1841..>2897
                     /locus_tag="KB909_002799"
     CDS             1841..>2897
                     /locus_tag="KB909_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838753.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSL"
BASE COUNT          971 a          426 c          471 g         1029 t
ORIGIN      
        1 tggtttttgt tttttttcat ttttttctcc tatttaaaag taataaaaat tgattctttt
       61 ctagtatatc atactagtgc tatgaaaaat ttaacgcaaa acttattaaa aaaagacaat
      121 tctagtatac tgaaaataga attaaaaaag gagaacaaca aatctatgaa aataagtaaa
      181 aaagcatttc ttttagtagt tcttatctta cttagtactt tatattcagt aaattttatg
      241 agaaatgctc aagaaattta tacaacaggt gatttatctt ttcatctttc acgaatcaaa
      301 gggttatctt ctatttttga agggccaatc aactatacaa catttaacaa ttatggagat
      361 ggactgaact atttttatcc ttttcttaca ataattcctg cagtcgtttt ttatggaatt
      421 tcaaataact taatattaag ttatgttcta tatatttggt tattaaatat ttgtacgatt
      481 ctgattagtt tttattatgg agaaaagttt tttaaaaaga tagatgctgc ttttttattt
      541 agttgtttat atacttttgc aacttatcga acagttgata tctattatcg atccgcaatt
      601 gcagaagcaa tcgctcttac gattatccca gctgttttat attatgctta tggattgata
      661 ttcaatagag aaaaaaaagt catcgcttta tctgtcagta taagtctact tgtgtatact
      721 catgtcttaa ctacactatt gtgtagtgca ttgattgctt gtatgattat agttcgtttg
      781 tttttaagca agcaaataaa aaacgatata aaatttgtgg tcgtgaattt agtaaaggct
      841 gtttttttga cttgtgcatt aactagctat ttttggtatc ctatgttgca gcagatgaat
      901 tatcaagaaa tacacagtcc cttcaaaaca gatttgcagc tagaagcact ttctatttca
      961 gatagtatca ttcaagcgtt aaataacgat attacaacat acactatggg gttattagga
     1021 ttggttgcgt tgatttttcc tttattcata ctgaaagaaa tggagaaaaa agaaaaaatc
     1081 atctatgttg gcgtagtttc tacatgggta tgcgtaacta atttatttcc atggtttttg
     1141 tttcaaaaaa caccgataag cttactccag tttccttggc gtatcttagg tatccaaatc
     1201 tttttttctt caatgatcat aacgcttgtt tttatgaaaa agactatgaa taaaaaatat
     1261 tcatggttaa tcattggcgc tactgtggtg tttctactcg tcacgtctat agcagcaaaa
     1321 gaaaattacg caaaagttat ccaatcaaaa cacggtcata ttgttatcaa tgaagaaaca
     1381 ctcccacgtt atacaacatc agatatggga ggattatacg attacgcccc aacagaagcg
     1441 ataaaagaaa ggcctcactt agaaaaacat gaagtaaaag taggagaatc gtgggaaaaa
     1501 gggaagtata aagctgcaga taataacatt acttacacag tggcaagcaa caaaaagcaa
     1561 aaagtgacag taccagtata tgcttattta ggtacacagg taaaagtaaa cggtaaagtc
     1621 gtaaatgact cttataaaaa acatggctta gtgaatgtgg atgtaaatgc tggagaaaat
     1681 aagatagaaa ttacaacaaa atatactcca actgctctca tggctttatg gatcagtatt
     1741 ctgacttatt gtttagtggt gtattcaagt tttaaacgat ttgcacctaa taagttgaaa
     1801 gattctcgat atgtgactaa aaaggagata aacaagaaga atgaaaataa ataaaaaagt
     1861 agtaatattg agtggattaa ttatagttag tagtatatat tctttcatct ttttcaaaaa
     1921 tacacagagt atttatacca ctggagatct ttcttttcac ttatctcgaa tcaaggggtt
     1981 atcgactatt tttaccagtc cgattaatta tgagacattc aattatactg gatatggtgt
     2041 aaattatttt tatccctttc tgactttttt tccagctgta atgttatatt ggatgacaaa
     2101 aaatttgatt gtaagctata ttatttacgt ttggttattg aacttgtgta caacactcgt
     2161 agcttatcat tatggcgagc ggtttttaaa acaaaaaaaa gcggcatttt tatttagttg
     2221 tctctatatt ttctctgctt atcggacagt agacatctac tatcgttccg caattgccga
     2281 agctatcgca ataacacttg ttatccctgt attattttat gcttatcaaa tcatctctgg
     2341 aaaagaagaa aagtatccgt ctgtaaagct agcattgagt atgagtttgc tagtgtacag
     2401 ccatgtacta tcaacattaa tgagtacagc attaattatc atttttattt ttattcgttt
     2461 ggtttctaaa ggtttcaaga atgcagattt tattgctata tttaaaaaat tatttagtgc
     2521 ggcaggaatg acattggttc tgacgagtgc tttttggtat ccgatgtttg aacaaatgct
     2581 ctaccaaaaa atcaacaaac ctagcgtgac aaatttatat gctcatgcat ctaatgtgtt
     2641 cgatagtctg actgaagcta tgaacaacga cttaactact tactcaatgg gactagttgg
     2701 tctgttatct ttatgtattc ccctgatttt atttaaaaaa ttaacaaaca tagaaaaaaa
     2761 gatttattat ggtacgtgtt tgacttggct agctacaact agtttggtgc catggtatct
     2821 tctgcaaaat acgccagcca aattgttaca atttccttgg cggatcttaa gcttgcaaat
     2881 aatattctct tctctga
//
LOCUS       DADVXK010000179         2817 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.186, whole genome shotgun sequence.
ACCESSION   DADVXK010000179 DADVXK010000000
VERSION     DADVXK010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.186"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            36..725
                     /locus_tag="KB909_002800"
     CDS             36..725
                     /locus_tag="KB909_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6838754.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            739..2241
                     /locus_tag="KB909_002801"
     CDS             739..2241
                     /locus_tag="KB909_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6838755.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            2254..2730
                     /locus_tag="KB909_002802"
     CDS             2254..2730
                     /locus_tag="KB909_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6838756.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT          916 a          380 c          564 g          957 t
ORIGIN      
        1 tccaaaaata ataaaaaatt ggagtgttta ggataatgga taaaaagagg tttttagatc
       61 ttatttcaaa aggtttgatt gtttcctgtc aagcattacc tggtgaacca ttttacaaag
      121 aggaagaaag tttaatgcct tattttgctt tggctgctca aagggctgga gcagttggta
      181 tacgtgcaaa ttctgttcga gatattattg aaattagaaa gtgtgtatca ttaccaatga
      241 ttggaattat taaaagagat tatccaccag aatctccatt cattactgcc actatgagag
      301 aagtagatga attagtagaa accggtgttg aggtaatcgc tcttgattgc actcttagaa
      361 atcgacatga tggactatct ataaattctt ttattactaa aataaaagaa aaatatcctc
      421 atcagttatt tatggcagat atttctacat ttgaagaagg caaaaatgca tataaagcag
      481 gaatagattt tgtaggaact actttaagtg gatatactga ggaaagtaaa aaacaagatg
      541 ggccagatat agatttgatt aaaaaattgg tagaagaagg gatttgtgta attgctgagg
      601 gaaggattca tactccagaa caagcaaaag agataaaaaa aataggagtt gcaggtattg
      661 ttgtgggtgg tgctattact cgaccacagg aaattgcatc aagatttgtt aaagcattaa
      721 gttaggggga gaaataaaat gtttaaaaaa ttttcacaat taggacgcgc tttcatgtta
      781 ccaattgcta tattaccagt agccggatta ctattgggac tgggaggagc gttaacaaat
      841 gagagtgcta taaatgctta tccattttta gatcaaccgt ggttgcatac aattttaagt
      901 attatgagtt atgctggaaa tgcagttttt gcaaacctag cactaatttt tgcaattggt
      961 attgctgtag gacttgcaaa tggagataaa ggaacagctg gtttagctgg tggagtagct
     1021 tatctagtat atactgcaac tattagtggg tttcttgaac ttttttcagc aaaagatgca
     1081 acactagata caggtgtagt gggatcaatt gttgttggtg gtactgttgc atttttacac
     1141 aatcgttata gaaaaattga attaccacaa ttcttaggtt tttttggagg atcaagattt
     1201 attccgattg tttctagttt agctgcaatc attattggtt ctttctttta tttaatttgg
     1261 ccaccaattc aaaatggttt agtagttgct ggtgaacaaa ttgcccaaat gggtagttta
     1321 ggaacttttt tatatggttt tttattgcgt ttaacaggtg ctgttggact acaccacacc
     1381 atttaccctt tgttctggta tacatcttta ggtggtaccg aaactgtagc tggatcaaca
     1441 attgctggag cccaaaatat tttctttgcc caactagctg atccaaacca cactggtctg
     1501 tttacttatg gtactagatt ttttgcagga agatttgcaa caatgatgtt tggattacca
     1561 gcagcatgtt atgcaatgta tcgtgcaatt cctaagaaaa atcgtaaaaa gaatggtggg
     1621 ctttatttta gcggggccct tacatcattt ttaactggaa ttactgaacc agttgaatat
     1681 atgtttttat ttgttgctcc ttggctttat gtgattcatg cattcttaga tggattatct
     1741 ttttattttg ctgatatctt aaatattcgt gtagggaatt ccttttcagg tggtttgatc
     1801 gactttttat tattcggtgt acttcaaggg aatgacaaaa ctaattggtt aaaattaatt
     1861 ccttttggta ttgcatgggc atttatatat ttctttgttt ttacattctt tatcaaaaaa
     1921 tttaaggtag ctattcctgg aatggaagaa gaatcagaag ttcattctga aaaagtaata
     1981 aacaaaaata catcattaca tgaagagtct cttatcatta ttgaagctct tggtggaaaa
     2041 gaaaatattg agtctgttga agcttgtgca actcgtttgc gtgttgctgt tacgaatggg
     2101 gagattattc aaaaacaaac aataaaagac actggtgcaa ctgctgtctt cgaagtgaag
     2161 ggtggcatcc aagctgtttt tggagggaaa gctgacttat taagtcaaga aatcaatcaa
     2221 atattaggaa aagataatta ggaggttttt aatatgtttg aaattttcaa aaagaaaaaa
     2281 caagaaactt tttatgcacc ttgttccgga aaaatcattt ccatcacaga agtaaatgat
     2341 cctgtctttt cacaaaaatt actaggtgat ggttttgccg tcatacctga tggttcaaaa
     2401 atttatgctc cattggctgg tcgagtaaca aatatatttc ctactaaaca tgctattaat
     2461 ataaaaagca actcaggcat tgattatttg attcatattg gaattgatac agttgaatta
     2521 caaggagagc ctttttcgat ttgtgttcaa gaaaatgatg aggttactcc tgaaacctcg
     2581 ttggttgatg tggattttga caaaataata aaatctggta aagatacttc tgttatagtt
     2641 gtttttccgg agaaaaatca gttcaatgat ttaataatag ataatggtcg aattgctcat
     2701 gggaattcat gtggaaaaat cactttttaa aaaagtgtat ataaaaagct ataaaataag
     2761 ctaaatagga tatttgtcaa atgaagttgg tgaacagaaa gaactgtttt ctttctg
//
LOCUS       DADVXK010000180         2790 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.187, whole genome shotgun sequence.
ACCESSION   DADVXK010000180 DADVXK010000000
VERSION     DADVXK010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.187"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            175..519
                     /locus_tag="KB909_002803"
     CDS             175..519
                     /locus_tag="KB909_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBB6838757.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="KB909_002804"
     CDS             520..939
                     /locus_tag="KB909_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBB6838758.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="KB909_002805"
     CDS             complement(1031..1381)
                     /locus_tag="KB909_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838759.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="KB909_002806"
     CDS             complement(1347..2678)
                     /locus_tag="KB909_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBB6838760.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
BASE COUNT         1040 a          501 c          535 g          714 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat
//
LOCUS       DADVXK010000181         2768 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.188, whole genome shotgun sequence.
ACCESSION   DADVXK010000181 DADVXK010000000
VERSION     DADVXK010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.188"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(75..1874)
                     /locus_tag="KB909_002807"
     CDS             complement(75..1874)
                     /locus_tag="KB909_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6838761.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(1998..2594)
                     /locus_tag="KB909_002808"
     CDS             complement(1998..2594)
                     /locus_tag="KB909_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6838762.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          976 a          522 c          480 g          790 t
ORIGIN      
        1 aaaacgcata tacctgcggt ggcaggttat gcgttttttg ttgtataaag acttttttca
       61 ttaacgattt ttgattagcc gactcccaaa acaaaattta gcagtttatc tgaataagtg
      121 atttcttcat ctgtttgttt cacactttca tttagtagtc ccatctcatc ggttatgata
      181 ccatccacac cataaaacat catgcgactc atagcatctg aatcgttgat tgtccataca
      241 tatacttctt ttccgtcttg gtgggcagaa ttaatgaagt tacggttgat cgtactatat
      301 tccattgtca gaaaatcagc aggcgtcaca gggggcccaa caatattgaa aggtaagatg
      361 tagcccacat aaaagtttgg ttctgcttct tttaaatctg aaacggtttg gtacgtcaaa
      421 ctttgcaaaa tatgatggtt ctctaagata actttgcggt atttatggac aaatcgttcg
      481 acaaggtcat ccgaatcttt tttagaggtc ttgatctcaa taagtaattt ttggtttagc
      541 ttatgtgctt tttccaaata agaatcaaaa gaacaaacag gggcttgcac tccgttttca
      601 gtaactgtaa gatttgtcaa ttctttcaat gtaagatcct gtggtgttcc atttacccct
      661 gttaagtgac gaagatttgc atcatgcatc actacgaaat gaccatcttt tgtttcctga
      721 acatccatct ctacataatc aggatgatag tctctgcttg ttttttcaag tgcttctaaa
      781 gtattttgcg ccccattttg ggtactcaca cctctgtgag agacagtcac tggttttgtc
      841 tgaacagctg aagtcagata atccatattg taaagacaga cgccaatacc gaaaaaaact
      901 gcaaaaagag tcaaaccagt gtttttcagc gcagagaaac gcaagttggg ggcttgtggg
      961 ataaaccact tagggatctc aggcaagaag ccttcgtcat ccatgaaatc aacaatgata
     1021 taaaaaatcc ctacggtaga catcacgata ttgaataata aaatcccttg taaaagcgtc
     1081 atagcaaaca cagcgctgat caatgcatag tctgggaaaa attgttcaac catactttgt
     1141 gccaaaataa caacgatata tcctaaagaa gaaaggagta aaatcgtacc gccaatcaca
     1201 ataaattggc ccgtgatggc caaaagacgc gatttggtca atgaccagct ttcccgaatg
     1261 gctgctcgaa aaggacgatc tcgtagaatc atttccggta aagcaaaaat cagtcgaatc
     1321 ccaatatagc caaggaaaat ataaacgagt aaaaaggaac tgacgatgat ccaacgatta
     1381 gcaaaaataa aatccataat gaaagcgggg atttttattt ttgacagtag atcagaatta
     1441 aaacttaatc cgctgatcgg tagaatcaat aaaaaataag caaggaaaaa caaaaaagta
     1501 atgggtctca ctttcttcag ctgaagtatc gtcaagtgta agagttgctt caaagagatt
     1561 ggttctttct ttttaataaa aaaaacactc atcaaaagaa aagtaaattc gaaataaact
     1621 aacagtaaaa tcgtcatcaa aactacgatt aacgagagta gaaccccagg atgttgagaa
     1681 aaaattgaag gaatattgtc ataagacaaa tagtcaattg cccctcggtg taaaataaaa
     1741 cgggtcgtac tgctcaataa gggtaaacaa ataaataaaa taaagccatg catcagcaag
     1801 acatcacgga aataagcttg tgttcctttt aaaaagtccc aagcattacc taagctacgt
     1861 ttcaaataat tcatcctatc acctgctctt cacattgtag cgcaaatcta atgaaaaagg
     1921 aaagggtgca gtgtgttttg cagacccttt cccagattta acattgtcaa tcaatgacta
     1981 attttacaaa ataaatatta tccaagaaga ccacttagat attgacctcc ataaatcaag
     2041 gccatactat ataagaaaat cgacagtggt ttagcaatca aaatgattag tgtatatcgt
     2101 ttcactgaca tgtttgtcaa tccagccatc aaacataacg catcgtcagg agcaactgga
     2161 agaaaaatag ctagagcaaa cagcttctca aaacggtttt gattatccag ccagccaata
     2221 tatttgttat atgtcttatc gctaatcatg gaaagtatga atggctttcc ataacgacgc
     2281 cctagcagaa aaatgataat cgaaccaatg cagattccaa tatagttata gataaatcca
     2341 gcataagggc caaatatcag gacaccagct gcagtactga tccctccagg aatgattgga
     2401 ataactactt gcaggatttg gatgaagaca aaaataatcg gtcctaaaat gatggaatca
     2461 cctactaatc ctcttaacgc attcaaatct ttgaaaacac ctaaattaat aaaataaatc
     2521 gtcagcgcga ttgataggcc taatccgata atggatatga aatttatcag ttttcgagag
     2581 gcagcaatat tcattattca tcaactcctt agaggttctt tgttaactat actttactag
     2641 aaaagcaact aactgcgcca ttttttgata tgacagaaaa caaacaattt tgtaagttca
     2701 tcataagtat aaaagattga tctcaaaaaa acatccaact aaagacttat ttaataactt
     2761 gttttttt
//
LOCUS       DADVXK010000182         2763 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.189, whole genome shotgun sequence.
ACCESSION   DADVXK010000182 DADVXK010000000
VERSION     DADVXK010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.189"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(792..2132)
                     /gene="glnA"
                     /locus_tag="KB909_002809"
     CDS             complement(792..2132)
                     /gene="glnA"
                     /locus_tag="KB909_002809"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBB6838763.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(2160..2552)
                     /locus_tag="KB909_002810"
     CDS             complement(2160..2552)
                     /locus_tag="KB909_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6838764.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT          813 a          599 c          451 g          900 t
ORIGIN      
        1 actacttttt cctacttgca gcaacagttt atatagctta tcgtagaaac aatctttttc
       61 tttcaccctt atttacctcc tttacgtaaa aaacgtagtc cacagttctc ggatttttgg
      121 catatctttt ctattaaata atatcaaaaa caaaacaatt ccactaattt tttcaaagat
      181 gacctttttt tcaacaaaag tgccttgtag ggattcattg aaggtaacga atcacataag
      241 taaaaaataa ggagatgcga caaaagtcgt gcctccttat ttctaaataa acggtgttct
      301 cctgccaact cctcggtcac aagtcacaat atccatcaaa catgagaagc tgtttttgaa
      361 attatttctt gtgattcgga gttaaatggt aggctcacaa cctctggata aacggtattc
      421 aaaagccagt ttctcggtat taagccaaat ttatgcaaaa atgtagaaag ccattttcac
      481 aaaatttttc ttaatactcg aaactaaacg tctttttcaa aacctcttgg taaacggtgt
      541 tcaaaagctt gcatctgcgg taataagttc agccaattca aaaacaagaa aagctgtttt
      601 tgcttggcta ttcttattac ttgttgcagg gcagcttttt cacaacctct ccactaaacg
      661 gtgttcaatc agctgaccct cggtattagc tcaaaaaacg gcaaaatatg aggaactatt
      721 tttccgttag tttctctaat actcaggtca aaacgctgat ttcacagcct ctaattcacg
      781 gtattcctgt tttaataaag ttctagatat tgttctcttt cccactcgga aacagtttgt
      841 ctgaatgccg cccattcgag acgttttgct tcaacaaaat ttgagaagat atgttgtcct
      901 aatgcgtcaa tcattacatt atccttacgc aattctttga tagcattatg gatagttgaa
      961 ggtaagtcct ggatatgtgc agcttctctt tcttcctcat ccattacata aatgttacgg
     1021 tcaacagctg ctggcggtgt gatctgatta cggataccgt ctagtcctgc ttgcaacaat
     1081 actgccattg ccaagtatgg gtttgcagat ggatcaactg accgcaattc caaacgtgtg
     1141 gataaaccgc gagattctgg tacacgtact aatggcgaac gattacggcc actccatgcg
     1201 acataaacag gcgcttcata acctggaacg agacgtttat aagaattgac tgttggattg
     1261 caaacggctg tgtaggcacg agcatgtttc agcaaaccac ctaagaaatg ataagctgtt
     1321 tcacttagtt ccaattcacc gtctttatca tagaaaacat ttccttcatc attgaacaaa
     1381 gacatattgc aatgcatacc agaaccattg atcccaaata acggtttcgg catgaaagtc
     1441 gcgtgaagtc catgcttgcg tgcaatcgtt ttgacaacga gcttgaaggt ttggatatta
     1501 tcacaagcat ctaccacatc tgcatattta aagtcaattt catgctgtcc tggcgctact
     1561 tcatgatgtg aagcttccac ttcaaagcct agactttcta attccaacac gatgtcacgg
     1621 cggcaatttt cacctaaatc tgttggtgca aaatcaaaat aaccaccttt atcattcaag
     1681 gtcgttgtga tcccaccgtc ttcgtctaat ttaaataaga agaattctgg ttcaggtcct
     1741 aaattgaaag aggtaaaacc aaggtcgcgc atatctttca atgctcgttt caaattcccg
     1801 cgaggatcgc cggcaaatgg tgtcccatcc ggattataga tatcacaaat taaacgagca
     1861 acttttccat gagcactttc ccacgggaag atcatccaag tggagagatc tggatacaaa
     1921 tacatatcgc tttcttcaat tcgaacaaat ccttcaatcg aagaaccgtc aaacatcatt
     1981 ttattttcta atactttgtc gatctggctc actggaactt ctacattttt gatcgtacct
     2041 aagatgtctg tgaacatcaa tcgtaaaaat cgtacgtttt cttcctcaat gattcgtttg
     2101 atttcttcac ctgttatctg tttctttacc atggtatccc tcttcctttt ttaatttatt
     2161 cagtcaaaga attgtctttg caatccttgc gactgataat gacctgtttt gcttaaccca
     2221 ccttgcgcca aaatctcatc acgaaaaatt tgtcgaacgt catgatctgt caacggcttc
     2281 ttgttttttg cttcttgttt tttcgcctgt gccatttcgt atacacgttt gatcccagcc
     2341 atattcaatc cctctgaaag atagtcttta atctcaagca acatatcaat atcattcagc
     2401 gaatacatac gtcggtttcc ttcgcttcgt tccggatgaa ctaaatcttg ttcttcataa
     2461 tagcgaattt gccgagcaga caaatcagtc agcttcataa ctgtaccaat tggaaatacg
     2521 gacatagatc ggcgcaattc cttttctccc atcagacgtc ccctttcgtt ttataagttg
     2581 gctaaagtgt accaattaaa aaaaatattg tcaactgcat atgttaggtt ttctaacatg
     2641 agatctctat tttttataaa ataacaaaaa aataagaaca caaaaaaggt atctagttga
     2701 ttttcgtacc agataccttt tattttttat tatactgtac tatcctttat tagtgttttt
     2761 att
//
LOCUS       DADVXK010000183         2683 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.190, whole genome shotgun sequence.
ACCESSION   DADVXK010000183 DADVXK010000000
VERSION     DADVXK010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.190"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(764..862)
                     /locus_tag="KB909_002811"
                     /pseudo
     CDS             complement(764..862)
                     /locus_tag="KB909_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1127..1582)
                     /gene="tnpA"
                     /locus_tag="KB909_002812"
     CDS             complement(1127..1582)
                     /gene="tnpA"
                     /locus_tag="KB909_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBB6838765.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1825..2683
                     /locus_tag="KB909_002813"
                     /pseudo
     CDS             1825..2683
                     /locus_tag="KB909_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          864 a          488 c          476 g          855 t
ORIGIN      
        1 tatgaacaaa acaataatat tgattcagtt gaattaagag aaaaagtttt gcgctctatt
       61 attgataaaa gtattgagtg aactaccccc acttagctaa acctaacggt ttttaacgat
      121 tgaagtaggc aattcttggg atgagagcat acttgatagc ttatttttta ctaatagcgg
      181 tggctcttat tgaccaaata tccctgtagt tcctacggtt cttgatttta tctaaagata
      241 tttttatcgt ggaagctatt gatcaacttg aaagaaaaac gtgtagctca ttatcactag
      301 tttatcgagt atggatgaag caatggatca tcctctctta aataaattta ttaaggatct
      361 gatccttcaa attttttcca tgatcgatga gcaggaacct actgaatcta aacgacatcg
      421 ggcacaagga attattaaga ttgctaagcg aatgttttct ataaagggtg ttctaagcta
      481 tacagtgtta attcaaaaga ttcccaatca tcttgtttat aagaacaacg ttgaagatta
      541 aaaaagtgtt tcaatgctaa aattgcaaaa tacttcaatg ttatgagaca aactgtctat
      601 aagaatcaat ttccacccat ttcatcactt gttaaaagtt tatgatcctt ttgattttta
      661 tattaattta tctgtattta atacagattt tatttattag ttcatctgcc tattgtattt
      721 tattttgttg ccttaccatc tgaagtaaat atactcttaa ttgtcaaatt aagttagaca
      781 gatcatcaat acttacgtaa ctcaaaaata cttccaaagg tgttcgataa tccagtgatt
      841 ttctaggaag attatttctg cgccagcatt ttctaatgtt tgaatttgtg ttttgtaatc
      901 ttggttgctt gtgctaattc ttgaatagcc gtaaattgcc aaaatttcat caccctttct
      961 ggacataagt ttctgacacc agttaaaatc aagtctatca gtaacccata cacccgtgag
     1021 gacgggtgta tttttaatcc ccctagaagg ggtcgacact cgctgcccct taaaagggga
     1081 tttttaaaag accgccaact gctcatcttc actcacttac ttctctttat tttttaaatg
     1141 gttctacgta ctctctttta cttataatat atcgaatgcg atcatcagct tcttgttcac
     1201 ggatgtattt ttcatttgtc ttttgattca atccgactgt actcacatag tatctcttcg
     1261 accaaaagga tttgtttccg tatttatatt tgagatttgc gtgctgctcg tggattagta
     1321 ccgcactacg acctttcaga taccccataa aactggatat acatattttt ggtggtactc
     1381 gaacaagcat gtgaatatga tctagcattg catgtgcttc tatgatttcc acatctttca
     1441 tttcgcacaa cttcctaagt atttttccaa gatcttttcg taattgccca tagattactt
     1501 ttcgttgata ttttggtgta aaaataatat gatacttaca attccaacga gtatatgcta
     1561 aacttttatc gtcatttgac atgaaaaaac tcctttcgat ctgatgagcg gttggtagcc
     1621 actcactagt atatcgaaag gagtttttat cgctaaagat acttcttcca cgcgtagaaa
     1681 cgcgcggttt tcttgtttcg cacgctttac gcacaaaact gactgaagtc attaagaaaa
     1741 taaaagggtc taaaactttt aagttttgta ccgaccccca aaagttagac caaaaaatct
     1801 aacttttgga ggtcggtatt ttttatggct aagtatactt ttgaacttaa attaaagatc
     1861 gttcatgatt acttggatgg taaaggcgga agtgattatc tggcaaagaa atattccatt
     1921 aaggctccat cacaagtgaa gcgctggatc aatgcctatc aagaatttgg tgaagagggt
     1981 ctagtaagaa agcgacaaaa gaaaaaatat tctgttcaat ttaagctgga tgcgatagag
     2041 ttatatctaa caagtgagct gtcctatcgt gaagttgcca acacacttaa catgaacaac
     2101 cctaatttga tcgctagttg gatgcgtcaa ttccgtgagg gtgggatcga tggactctca
     2161 aaaacgaaag gatgtccacc tatcttgtct aagaaaaatg aacccaaaaa taagaaaaaa
     2221 tctacaacta aagcaacgtc taaagaacgt gaacgcatcg aggagttgga gaaacgagtc
     2281 cgttcccttc aaattgaaaa tgccttttta aaagaattga ggaagctgcg aaaacaggaa
     2341 gcccaacaac gacgaatgaa gcaatcgcac gaatcatcgc aagcctccga ggaccgttta
     2401 aattagttga gcttctagaa actttaaagt tccctaaggc aatctttatg tactggcaaa
     2461 aacgattgga ccgtaaaaat ccagatcaag agattgaagc ggaaatgctt aaagttcggg
     2521 agaagcacaa ggattatggc tgtttacgga tgaccaatga actaagaaac cgcggtttct
     2581 ctatcaataa aaagaaagtt cagcgcctga tcaagaagct aggaataaaa gtaacgacat
     2641 acacacgtaa atcacggcgc tacaattctt atcgaggaca agt
//
LOCUS       DADVXK010000184         2665 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.191, whole genome shotgun sequence.
ACCESSION   DADVXK010000184 DADVXK010000000
VERSION     DADVXK010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.191"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(46..1239)
                     /locus_tag="KB909_002814"
     CDS             complement(46..1239)
                     /locus_tag="KB909_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6838766.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1303..1683
                     /locus_tag="KB909_002815"
     CDS             1303..1683
                     /locus_tag="KB909_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBB6838767.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1757..2119
                     /locus_tag="KB909_002816"
     CDS             1757..2119
                     /locus_tag="KB909_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838768.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT          908 a          427 c          487 g          843 t
ORIGIN      
        1 gacgaaacct agtaaggtct cgtcctttta ttttgaataa atgatttaat cgattgtctc
       61 taaagcatac ttgattcgat taagtccttc cagtaaagtt tcttctggac aagcaatatt
      121 caagcgcata tgcccatgac cggaaggacc aaacgtgatg ccaggattta atacgacttt
      181 tcctttccga acaagagtgt tctccaattc ttggtcgtct gaaatatagg cggtaaaatc
      241 taaccacatt aagtaagttc cttcagggtt cattattctc actttcggaa gatactgttc
      301 aaaaaactga ttaactgttt gaacattttt ttctagataa ggaatcagtt ggcttaacca
      361 ttctccaccc gtctcataag ccgcttgggt tccaatcagt ccaaaagtgt tgatttcgtg
      421 ctgttggttc atcactaaat gtttttcaaa atcagctttc atctctggat ttttgataaa
      481 taccattgaa tttttgattg cagctagatt gaaagtcttg gttgcggaag taaaagcaac
      541 tagtagatca tctaaattag gatcaatcgt tagcatggaa gtaaatgtat gatcgaataa
      601 agttaaatct tgatggatct cgtcactaaa cagaatcact tgatgtttta aacacaattc
      661 gcttaactgt ttcaattctt ctttgctcca aacacgccct ccaggattgt gaggattgca
      721 taaaatcatt gcttttacat tgttttcttc gatttttttc tccatgtcag acaagtccat
      781 gatgaaatga ttattttttt ctagcaaaga gcttcgaacg atgtgacgtt gatttgtttc
      841 tataatagag gaaaatggag gataaactgg gtcatgaatc aaaatagaat cgcctggttt
      901 tgtaaaagtt tgtactgctg cagctaaact ggttaacaca ccacttgtaa aaacgatatt
      961 ttctttcgtc aactccacag catggtgttg gcgttcccaa tgaatgatag cctgatatag
     1021 tttatcagac agagtggcat aaccaaagat tccatgtttg atgtattcac taaacgcttt
     1081 agctacccca ccgggagaca agaagtccat atctgctacc cacaaaggaa gtaagtcatc
     1141 catttgatat gtctcagcaa ttgcgtccca ttttacactt tctgtatctt ttcttgaaat
     1201 ctgtttatca aattcgatca tcttaagacc tccagtcatt ttcgtcgctt ctttttttga
     1261 gctatttaca gtataatgat aaatgcgaag agagggaagt agatgactta taaaattgga
     1321 caaataattg aaggaaaagt gacagggata cagccttatg gcgcattcgt ttctcttgat
     1381 aacgagacgc aaggacttat tcatgtttca gaagtacaat ccggttatac gaaaaatatc
     1441 cattcattgt taaaagtcgg acagccagta acagttcaga tcatcgacat tgatgaatat
     1501 tccaaaaaaa tcagtttatc tttaagaacg ttagaaaaaa caaatccagc tgttccatat
     1561 cgcagaaaaa ggtatttcac gaataaaaat cgtaagatcg gatttaccac tattgcggag
     1621 cagttaccta tttggataga agaagcatta tctgaactag aacggaaaga aaataagaaa
     1681 taaaaagtgt attttttctg aaaatgtgct agaattttta tgtaagccat agaacaagtt
     1741 gatcgaggtg gaaattttgg caagcaaaag agttgctggt acaattatgt tgcatttgga
     1801 ggatggtact aaaaaatttt tggtccattc aattgatgac aagttggaat ttgcgttagc
     1861 ggaactttct gaaggaaaga ctggtttagc gaatatactt aatttcttaa aagaaatagt
     1921 tcatatcgat gttagcaaga ttagtttgat ggaattgaca aatacacata ttaaagagga
     1981 aaatgttccg ttgtttgtct ttgaaactga acaaaagaat caaagagaag aattaggcga
     2041 aggatatatt tgggaagaac caggtcaaat gcgctctgtt cttggaactt acgaagtaga
     2101 gggagtgcct ttcttctaaa atacagatta agcgaacaaa gaagtttgaa tttttttcaa
     2161 acttcttttt ttattgtttg gtccaaaaaa tacaatgaaa tgttctgcta aagatagttt
     2221 tttagtgcat tttattttca aaatatgttg aaaacggttg tataacgaat aataataatt
     2281 gatcgaaaaa tcatttcaca aagtaatgct taatttatag ttgaccaagg aagaaataca
     2341 tgataaattt aacagcgttg attctgaagt ggatgttata tcacatttct aaaaaattta
     2401 aaaaatagtt attgacatgt tactaacgac atgataagat aactgagtcg ttaaaaaaga
     2461 accacttgcg aagcttgatt ctatcgaaaa aaacttcaaa aaagttcttg acaaataaca
     2521 aacgataagt tatgataaat gagttgctga aagatttcga aaaacgaaat cgaaaaaaac
     2581 ttttaaaaaa gagttgacaa tcgcttgtct ctctgatatg atataaaagt tgctacggca
     2641 gccaaaaacg aatcgggaaa cactc
//
LOCUS       DADVXK010000185         2650 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.192, whole genome shotgun sequence.
ACCESSION   DADVXK010000185 DADVXK010000000
VERSION     DADVXK010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.192"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(195..560)
                     /locus_tag="KB909_002817"
     CDS             complement(195..560)
                     /locus_tag="KB909_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838769.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            768..1250
                     /locus_tag="KB909_002818"
     CDS             768..1250
                     /locus_tag="KB909_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838770.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1447..2337
                     /locus_tag="KB909_002819"
     CDS             1447..2337
                     /locus_tag="KB909_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBB6838771.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          904 a          432 c          525 g          789 t
ORIGIN      
        1 atgtttccac ctcaaattca atatctatta ttggaatcat tattgctgca attattacac
       61 aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa atagaaaaac tagtgatagt
      121 tttggtgata taagaaaaac atatatgtat aaaaagaaga aagtagcttc tctttgtaca
      181 tatatggttt gtttttatgg atgccgagct tttttataag ataaggctac cgcccataac
      241 gacccaagga tttgtggaac taagtaaata cctgcaagaa gcaagatcag ctgggtcggt
      301 tttaaaggat gatagaagta acgccattca gtaaaattgg cgcaaaataa ataggaagtg
      361 acagtagata taatattggc aatgaataaa gatataatac gcctgttcct ttgaaaataa
      421 tatccagcaa aaagagataa aaatatcaat gtgatgaacc cgcttacgga atgataacga
      481 aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag ataaaagcaa cggaaggttt
      541 ttccagcaag tttttatcat ctttcatcac cacctaacaa gtgttattat tttgttagtt
      601 ttattgtaaa ttgaatcctg caataatcaa ttactttttc attatttcta gattaaatga
      661 ataaactctc atgccattat ctctaaaaaa aaagtttttc cccctaattt ttttagatag
      721 aaaattgtat agtatgatga gagaaaaagt agtttggggg aacgttaatg agaagaaaag
      781 cagtaatcga tcggctttat ttattttttt ggttttttcc tatcgttttg ctacctttta
      841 catgggtaaa tgctgttgta caaggtgcgg agatattagg cctgatccaa ggaagcggat
      901 ttgtggtttc taggaatttt ccagctttga ttgttttcta tttagtgata agtgtaggtc
      961 tcttattacc aaaatctctg atcaatcact acaattggca gctgctttac ttttcttgct
     1021 tattagtatt tacatctacg ttttctttgc tgcctcgctt gattatcggc cctaatggtt
     1081 tgagcgagag tggattgaag gatttagctt attcctccat gtatttcttg acgatcaaac
     1141 catggttcta tttagtaatt gcctcattta ttcttgcaac atttttttac ttctggacag
     1201 aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa taactattga tggtggatca
     1261 tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc tcatatgctt tttttattat
     1321 tatgtaaaga atgcgaaaaa cgtttacatg atttttacat aacttaacta tatttttaca
     1381 gcaaccatac gagggattta cagtcgactg ataaacttta gttgtaaata agaaaggagc
     1441 aataaaatga aaaaagtatt gtttactcta ggtatgatgg gaattctttt agccggatgc
     1501 ggctcaggat caggaaatac agatggctct gccacacaaa ataattcaag tgactcaaat
     1561 gaacaagtaa aaatcgttgc ggtaggttcg acagcattac agccgttagt cgatgcagca
     1621 caagaaagct ttgtacaaga aaatccaaat tatcaaatct ctgtacaagg aggaggaagc
     1681 ggaactggtt tgagccaagt cgaagctgga gcagttacta tcggaaactc tgatgtattt
     1741 gcagaagaaa gagacggagt tgatgcttca aaattagtgg atcataaagt agcagtggtc
     1801 gggatggcac caatcgtcaa taaagataca gatgtcaaag atatcaccaa acaggaattg
     1861 attgatatct ttacaggaaa aatcactaac tggaaggaag ttggcgggaa agatcaaaaa
     1921 atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg cgacattcga aaaatgggga
     1981 ctggatggtg ctacccctgt gcagtcccaa gaacaagatt catcaggaac agttcggcag
     2041 ctggtaagtc aaacaccagg agcaatcagc tatttagctt tctcatatct cgatgattcc
     2101 acacaagcac taagtatcga cggtgtagaa ccaaaagaag agaatgtagc agataacagc
     2161 tggggaatct ggtcatatga acatatgtac acgaacggaa aaccttcccc tgaagtccaa
     2221 aaattcttag actacatgat gacagaagaa atccaagaag gacctgtcaa agaattgggc
     2281 tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg aaggaaatat caaataacta
     2341 gcagataaac atgccacggt agtcgttact attaaggaaa aatcaactat gtttccccac
     2401 atatacattt ttcctttaat tgtgaaaaat agttcctcat attttgccgt tttttgagct
     2461 aataccgagg gtcagctgat tgaacaccgt ttattcgaaa aaaagagcta cgacatagaa
     2521 ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg tgaagacaaa tttgaataaa
     2581 acttagaccg atatgcggcg cgttctgtgc gccgcatatt tttttagttt tcaaagatca
     2641 gaccttgttg
//
LOCUS       DADVXK010000186         2566 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.193, whole genome shotgun sequence.
ACCESSION   DADVXK010000186 DADVXK010000000
VERSION     DADVXK010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.193"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..78
                     /locus_tag="KB909_002820"
     CDS             <1..78
                     /locus_tag="KB909_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6838772.1"
                     /translation="LELFFAVFLFLGKNSLKQTKKKELV"
     gene            complement(108..617)
                     /locus_tag="KB909_002821"
     CDS             complement(108..617)
                     /locus_tag="KB909_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBB6838773.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(729..1727)
                     /locus_tag="KB909_002822"
     CDS             complement(729..1727)
                     /locus_tag="KB909_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6838774.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1928..2512
                     /locus_tag="KB909_002823"
     CDS             1928..2512
                     /locus_tag="KB909_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6838775.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          801 a          475 c          483 g          807 t
ORIGIN      
        1 ttagaattat tttttgctgt ttttcttttc ttaggaaaaa atagcttgaa acaaacaaaa
       61 aagaaagaac tcgtctaaat agacgttttc tttctttttt tgttgaatta ttgagtaagg
      121 cgacttcttt tttctggttc tttgtgtgct aatcgactgg cagcagcagc ggcgatcgct
      181 ccgacgatat catctaagaa ggtatggaca tgaacgccat cgtggctgtt tagttctttt
      241 aaaataccag gtttcacctt gtcgatataa ccataattcg taaagccgat cgtaccgtaa
      301 acattcacga ttgacaaggc taggatctca tcgataccgt aaaggccttc gtcatcttcg
      361 ataatatgtt gcaacggact catcaatttt ttcttttctg ctaatatatc taattggatt
      421 ccagtgataa tggcgttatg tacttcacgc tttgttagca cgctgttgac actttcagta
      481 caatccgcca aagtcaaatc agaaatatag tctttttgta aaaacatgac aagttgtgcg
      541 atatcttcta cagttacgcc acgttccttc aatagttctc ttgccttttc ttctaaagtc
      601 tcagttttga cgaccatatt attgctcccc ctttattttt tctttctcta tttcatgtta
      661 acggaacatg aaaaaaatgc aagaaactgc tttcgggttt aacttgaaat gcaaagagat
      721 ataaaaaatc aactaggacg aagattttta tcgtataagc ttgtgctgtg accaggctga
      781 gttcgttcct ttggattaat atagtgtaaa gcgttgttca ctgcagtagg tgcttcaccg
      841 agcccagtag caatcagttt cacttttcct tcataggtac agatgtcacc agctgcataa
      901 acgcctggaa tagaagtaga catatctgat tttacagtaa tggcatttct ggtactatca
      961 agtccccaag aagaaagatg ttctaaatta gaagagaatc cataattgac gatcagagaa
     1021 tcaatcatca aatcaatcgt ctcgtcactt ttcacttttt ttaaccggat atctgtcagt
     1081 tccccattat tgcctgataa tccatcgatg agatagggag taagcaagtt gacagatgaa
     1141 gatttcaagc gtgatacact atgttcgtgc gcacgaaatt ccgggcgacg atgaatcaag
     1201 taaacttcgc ttgcaatagg ctctaacatc aacgtccaat cgatagcaga atcaccacct
     1261 ccagcaatag cgactttttt tccagcatac ttcatcaaat cattcacgaa ataatccaat
     1321 ccgtggtttt caaatgattc agcattatct aaattcaatt ttcttggctg gaatgaacca
     1381 tttcctaaag ctaaaatgac tgctttggaa taatggatgc ctttatttgt agtaatctcg
     1441 ataacttcgt cttcacgagt aagcgagaga acttcttctt ttaaatggaa tgtatggtta
     1501 aaagtagtta attgtttttc taattgatcg attaattcac ttgcttttat tgctggatac
     1561 ccaggaatat cgtaaatata tttttcggga tacaaagttg ctaattgacc accaagttga
     1621 ggtagactgt caatgatttt tgttttagct tggcgcattc ctgcgtaaaa agcggcaaac
     1681 atccctacag gacctgcacc gatgattgta atgtcataga tttccataaa aattcctccc
     1741 ttttcacact atatcagaat ttaattgaga atgcttctca aaaatgtttg aattcgaaat
     1801 cgaaacggta agttatagaa tgtatctagt gatgaaaaat aaaagaaaac aaatctagta
     1861 tttttacgag aggttaggta ttatgttatt attattatga agtatgcaaa tattaggagg
     1921 aaacaatatg gcattcccac aactagattt aaaaagtgaa aaaggaccaa aagctgttat
     1981 caaaacaaac cgtggtgaca ttactgttca attattccct gaactagcac cgaagacggt
     2041 tcaaaatttc attgaacttt ccaaaaaagg ttattatgat ggcgtgattt ttcaccgcgt
     2101 tattcctgat ttcatgatcc aaggcggcga tccaactgga acaggaatgg gtggcgaaag
     2161 tatttatggc gaaagttttg aagatgaatt cagtcgtgaa ctgttcaacc ttcgcggagc
     2221 tttatctatg gcaaattcag gtccaaacac aaacggaagc caattcttta ttgtaaataa
     2281 cacaaatgtg ccagctaata tgcttggaca actagaaggt gctggattcc catcagaaat
     2341 cattgaagcg tataaaggtg gcggaactcc ttggctagat ttccgacata cagtctttgg
     2401 acatgtacta gaagggatgg acacagtaga tgaaatcgca aatgtacaac gtggtccaca
     2461 agaccgacct gtacatgatg tagtgattga aacaattgaa atttcagaat agtttggtat
     2521 ggtacggagt aattatgaaa aaggacgaaa cctagtaagg tctcgt
//
LOCUS       DADVXK010000187         2549 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.194, whole genome shotgun sequence.
ACCESSION   DADVXK010000187 DADVXK010000000
VERSION     DADVXK010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.194"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(94..1137)
                     /locus_tag="KB909_002824"
     CDS             complement(94..1137)
                     /locus_tag="KB909_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBB6838776.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1514..2479)
                     /locus_tag="KB909_002825"
     CDS             complement(1514..2479)
                     /locus_tag="KB909_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBB6838777.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
BASE COUNT          914 a          470 c          482 g          683 t
ORIGIN      
        1 tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga cattgttcca
       61 tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc aaataaatag
      121 taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga agcgtgtacc
      181 ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag cagtgatctc
      241 aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag aaaacaagct
      301 gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta attttcgttt
      361 tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca tgaatttttc
      421 aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata gcatggcgaa
      481 ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa cagattggag
      541 tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact gtaatccaag
      601 aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga tgatctgtcc
      661 tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag aagaaccaca
      721 aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca gttttttacc
      781 aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa caattccttt
      841 tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa aaacagagaa
      901 ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct gtttaaaaaa
      961 agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta actgtggcag
     1021 ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta aaccgggtaa
     1081 gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg atttcatttg
     1141 atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc actaaaccag
     1201 tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct tgtttcgaat
     1261 aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa aaatttgaga
     1321 agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt acgacctctt
     1381 ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta caaaaacatg
     1441 aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt ttcacaacct
     1501 attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg ctatgttctt
     1561 taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt gcaaacagac
     1621 attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg ttgaagtaat
     1681 gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag gctgcatagc
     1741 ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg aaatacaata
     1801 cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca aagtttttaa
     1861 gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc ggacgtgtcg
     1921 gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat aagaacgcat
     1981 agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag ttcccggcag
     2041 ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa attgcttcaa
     2101 ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg atcacttgga
     2161 agataacagc gcacagccaa atgaatttga caattggtgc aatactttca tatgaaacaa
     2221 aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag gcgatgattg
     2281 gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca aaaatgaata
     2341 tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg tgatagtctt
     2401 taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg atcggaataa
     2461 ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt ttagtaccaa
     2521 gatgaacgaa tacattgtaa aatgaatag
//
LOCUS       DADVXK010000188         2516 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.195, whole genome shotgun sequence.
ACCESSION   DADVXK010000188 DADVXK010000000
VERSION     DADVXK010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.195"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            175..>2516
                     /gene="esp"
                     /locus_tag="KB909_002826"
     CDS             175..>2516
                     /gene="esp"
                     /locus_tag="KB909_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBB6838778.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTS"
BASE COUNT          916 a          387 c          507 g          706 t
ORIGIN      
        1 aatatccgaa aaaaacatga agaaatgtac tttttttgtt gtaatgttca tgaaattctc
       61 taagtaaatt agttaacata aggttagtaa gattcctatt ctgtgaataa tacgtatcag
      121 atttatcttt tattcttact aggaaagtaa ttattaaggg agttgatttg aataatggtt
      181 agcaagaata ataagagagt atttctagaa aaaacaaaga aacgagtatt gaagtacagt
      241 atcaaaaaat taagtgttgg ggttgcatct gttttgattg gtgttggtct tgtcttggga
      301 acaactgaac tagttaaagc acaagatgaa atttctccaa gcagcccact tgaaacagcg
      361 ataagctccg tacaagtagg tgacaaagta gcttcgggga atacttttca ggagaatcct
      421 ggttatacga aaaattataa cttttcggat ttacaattta gtcctcaaga actaactgga
      481 gacacactaa aaggcaatac aattggattt gaagtttacg gaaaacataa tattgcagca
      541 tcaactaaaa actgggaaat ccgtcttcaa ttagatgaac gattagctaa atatgtagaa
      601 aaaattcagg tcgatccaaa gaaaggaatt ggatcttcta gacggacctt tgtaagaatt
      661 aatgattcgc tgggtagacc tacaaatatt tggaaggtca attatattcg tgcaagtgat
      721 ggattatttg ctggggcaga aacaaccgat acgcaaaccg ctcctaatgg ggtaattacg
      781 tttgaaaaga gcctagatga aatttttaaa gagataggca tagacaatct caagaccgat
      841 cgtttaatgt atcgaatcta cttggtaagt catcaagacg atgataaaat tgtaccgggt
      901 attgatagta cgggctactt tttaacagat tcagatgatt tctataatag cttagatgta
      961 tctgaaaata atcctgacca gtttaaacat ggatcagtaa gtgcaaaata tgagaaacct
     1021 aatactcaaa caaaagatgg ttcaggatcc acaggtgcta atggagctat aatcttagat
     1081 cataagttaa cgaaaaatta taatttctca tattcatctt ccgcaaaggg cacgccttgg
     1141 tatgctaatt acaaaattga tgaacgatta gttccatatg tagcgggtat acagatgcac
     1201 atggttcagg ctgacaaagt aacatatgat gtttcgtttg aatccggaac aaaagtagct
     1261 gatttagcaa tcgagcgacg ggaaggtcat gaaaattatg gcataggttc aataactaat
     1321 aatgatttaa ctaaacttat cgattttgct aatgcaagtc cacgtccagt cgttattcga
     1381 tatgttttac aattgactaa gccattagat gaaatcttag aagatatgaa agcaacagca
     1441 caagttgaag aaaataaacc atttggtgaa gatttcatct ttgattcttg gttgtcggat
     1501 acgaataaaa aattaatcca gaacacttat ggaacaggtt attattattt gcaagatatt
     1561 gatggtgatg gaaaccctga cgataaagaa gagagcggag acacgaatcc atatatcggg
     1621 aaacctgaat tagaagaagt atatgatgtt gacacaacag ttaaggggaa agtattcatc
     1681 cacgagttag cgggaacagg tcacaaagcc caacttgttg ataaagaagg tactgtatta
     1741 gcagaaaaaa ctatcgctcc aaatgaaaaa gatggggctc caatttcaga tactgtagaa
     1801 tttgaattta cgggtgtaga ttcaagtaaa ttaatcgcga aagatgaatt aaaaatccaa
     1861 atcgtttctc caggttttga taaaccagaa gaaggttcaa ccgttattaa ggaatcacca
     1921 aaagcggttg ataaacaaac cgtggtagtt ggatttaaac cagatgctaa agaatcaatt
     1981 cggaataata aaaacttacc tgaagatgca gagtattcat ggaaaacaga gcctgatact
     2041 tctaacgtta ctgatagtac gaaaggtatt gtaactgtta agatcggaaa tcgaactttc
     2101 gacgtggatg tagagtttgc tgtaaaagct tctcaagcta tggaaaatga tgcaacatac
     2161 gtacctataa caacaactcc agaaacgaca gttcaaagtg gaaaacctac atttgataaa
     2221 ccagatgttc ctttagctaa agatgccttt tcaatttcag atgtctataa taagtacttc
     2281 ggtaatgcaa gtgttgatgc aaacactggt attgttacat tcactccagc taaaggtgta
     2341 ggagaatcgg agccgattac tggaacaatt cctattaaaa ttgtttacca agatggttct
     2401 gtaggcacga ccgatttagc agtaactgta agtaaagata tttatgaaaa tccaggagaa
     2461 aacattcctg caggctacca caaagtaacc ttcaccgcag gggaaggaac aagtat
//
LOCUS       DADVXK010000189         2507 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.196, whole genome shotgun sequence.
ACCESSION   DADVXK010000189 DADVXK010000000
VERSION     DADVXK010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.196"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(168..734)
                     /locus_tag="KB909_002827"
     CDS             complement(168..734)
                     /locus_tag="KB909_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6838779.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(734..1690)
                     /locus_tag="KB909_002828"
     CDS             complement(734..1690)
                     /locus_tag="KB909_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBB6838780.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1690..2346)
                     /locus_tag="KB909_002829"
     CDS             complement(1690..2346)
                     /locus_tag="KB909_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6838781.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
BASE COUNT          760 a          523 c          463 g          761 t
ORIGIN      
        1 gaacagccaa tcaaaaacag cttctcatgt ttttgatttg gttggactta ttaccgcaga
       61 tataagcttt tgagcaccgt gaataaagag gttatgaaat caacgctcta acctgagtat
      121 tagagaaaaa aacgcaaaac atatcattta tgttttgcgt tttttattta tctttttttc
      181 tcaatacaat ataaaatagg cggctggttc ttttggttga taaaccgata attcagcaca
      241 ttatatgttt cctgtggcag tttggaacaa aaagaatcaa ccatatccag ttctttttct
      301 ccaccttcat gaccatagta gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc
      361 aatatttctt ccatagctgt gcgtgtagtc tctggcatag tgatgattgc tttatcactt
      421 tttgggagat accctagatt gaaaatccct gctttgagat tttgttgttc agctatcact
      481 tctcctaacg tttcgtggcc ttgtagaaac aatgagacac gttcttctaa ctgacgctgt
      541 tctagccttt cacgagtagc atcgattgct tgttgctgga tatcaaaact atagacatga
      601 ccagtttttc cgatgtgttc tgctagaaaa accgtatcgt ggccattgcc catcgttgca
      661 tctacgacgt gatcccctgg ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa
      721 gcagtttgca acatcagacg ctcacctttt tccgtacatc atattttcct tggaagctat
      781 ctctgcgaag aagttcttca tcaattgcat tcaagacttc ccattttttc aagctccaca
      841 ttggtccaat caaggaatcc cacggcgcat cccctgtcaa acgatggatg atgatctctt
      901 ttggtatcat ttccagctgg tcgcaaatga cattgacata gtcaggacgg ctcattaatt
      961 gaaggcgacc ttcatgatag tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat
     1021 ggagcttgat tccttggata tctgaatcta aaatggtgcg tctgacattt tctttcatca
     1081 tttctaaact ttcgcctggt aatccgttga tcaaatgcgt acaaacacgg atattatgtt
     1141 tgcgtaattt agccacgcca tctaaataag tttgataatc atgtgctcgg ttgatcagtt
     1201 ttgaagtttc ttcaaaagtt gtttgcaatc caagttctac ccataaatac atccgctcgt
     1261 tcagttcagc aaggtaatca actacttcat ctggcagaca atccggtcgt gtaccgactg
     1321 ataatcctac gacacctggt aaattgacta cttgctcaaa tcgttctttg attatttcaa
     1381 ctggcgcatg ggtgtttgta aaattttgga aataaacgat gtattgttgg acatgaggcc
     1441 atttttgatg catcatgtcg atttctttct ggaattggat tggaagaggg tcttcaggtg
     1501 caacgatcat gtctcccgaa ccagatacac tgcaaaaagt acaaccgcca tgggcaacag
     1561 tcccatctcg attcggacag tcaaatcctc catcgatcgg caccttgaaa attttcccgc
     1621 caaactcatt tcgtaaagcg taattccaag aatgatatct tttatttcct tctgaataag
     1681 gaaaagtcat taaaagtcct tctttctgta agagttatct atttgttttc ttttttctct
     1741 atacactgga taagtcaggc acagccaaga aagactgagt aagtaaccgc cgatgatatc
     1801 agtaggaaaa tgaacgccca gataaatgcg gcttatcccg acacttacta taataaacat
     1861 catcagcaat tgaagcaatg tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa
     1921 tagtaaagaa ccgtaaagaa tcatactgcc tgctgcatgt ccactaggga aactgtaact
     1981 tgtttcaact actaagtgcg ccaatgaagg acgctctcgc atgaaaaata gtttgatcac
     2041 cgggttgatg attccagcaa ttacaataaa tccagaaacg aaccaaaatg tttctgccct
     2101 ttttttctta taccacatcc ataaagccgc acaagcaaat aaaatgatga cggtaagagg
     2161 attaccgaat ttagtcataa agagttggta gctgttcaga tcaggataag aagctctgac
     2221 aatgcctgta aaccactgat cgaaaccaga aagccacgac agatggaact ttacgatcca
     2281 gcccaaaatg aaaaacagga caagaaagaa gctaccagcc acctgaaatg atgttttata
     2341 tttcatacaa ttcctccttt gaagcaatga cttattatag catttttggt ccagcgaaaa
     2401 aaacggtaaa gagataaaac caatgtatga ttcctctttg aataaccaat attcttataa
     2461 aaaaaataac tgtaatcgga aagacatttt ttggtaatgc aaatgaa
//
LOCUS       DADVXK010000190         2480 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.197, whole genome shotgun sequence.
ACCESSION   DADVXK010000190 DADVXK010000000
VERSION     DADVXK010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.197"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            21..542
                     /locus_tag="KB909_002830"
     CDS             21..542
                     /locus_tag="KB909_002830"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838782.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            543..860
                     /locus_tag="KB909_002831"
     CDS             543..860
                     /locus_tag="KB909_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6838783.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(1017..1181)
                     /locus_tag="KB909_002832"
     CDS             complement(1017..1181)
                     /locus_tag="KB909_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBB6838784.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1284..1805
                     /locus_tag="KB909_002833"
     CDS             1284..1805
                     /locus_tag="KB909_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6838785.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1792..2265
                     /locus_tag="KB909_002834"
     CDS             1792..2265
                     /locus_tag="KB909_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBB6838786.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKFCRLKIGQNR"
     gene            complement(2272..2430)
                     /locus_tag="KB909_002835"
     CDS             complement(2272..2430)
                     /locus_tag="KB909_002835"
                     /inference="COORDINATES: protein motif:HMM:NF024064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBB6838787.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
BASE COUNT          806 a          461 c          539 g          674 t
ORIGIN      
        1 tggattaagg aggaagagta atgcatatag gagataagat acataaattg agacggctta
       61 ataacgaaac aatgaacgac ttagttaaac aaaccggact gtcaaaatca tgggtatctg
      121 atattgagtc tggaaaaaag caacgcgctg actttaataa gatatgtgca atagccaaac
      181 attataaagt tagcttagaa tactttcagg atgattattt ggatagtgat gaacacgagg
      241 atattattcc tttgacagac gaaacaagag ttaaatcagt gaaatcgctt gaacaaagcc
      301 taaagtatct gaataacaaa caagaaccta accttctaga gatcaaacta aaagatactg
      361 actcagtacc agaggtttat tacaaaggtc agaagttaga gggattgata gatgtaagct
      421 atcactacca tacaacaact gatgtggtag ctggttcaac aaacgacatc aatatggagt
      481 acctaggtga agtaactaag tatccagata taaaaacaat cggacacaag agagatgtgt
      541 aaatgaaaga agctagacct agagacgaga tagacaaact atacaagacc aaacgatggc
      601 gagacctaag gcaagtagta atagctaggg acttcggcat gtgccaagag tgcaagcgtc
      661 gagggcggaa cacaaggggc acgatcatcc atcacatagt cgaggcgagg gaagacctgt
      721 cactgttctg gtccgtagat aaccttgaat gtatctgtgt agcttgtcac aacagagagc
      781 atccagagag atcaggcggg aagaagaaac caaaacctaa atcacatatc gttaaaatgt
      841 attcaactcc tgaaagataa gtttgcagcg aaatgaaggt agccccccta ctctaaaaga
      901 ttaaagagta aggcttgaga agaacggtgc tgtccttcct tcgtaaaaag accgcttttc
      961 aagttttttg gagaaaaagg aaaaagccga ccaatttaag ccggctttgg acgaagctat
     1021 ttcttagtcc atttgtttcc tttttgagaa gtaggaggta atcggtcgcc tggatcaatt
     1081 tttacttctc gtccgccttg gacatttcca ccacgaggtc ccacttcttt ataggttcct
     1141 tttggtttat tgtcttcgcc gggtttatag agttctccca taggaatccc tccctaaaaa
     1201 aatttcggca cagcactgcc gataacttaa ttataaggat tgtgataacg atttcaatat
     1261 atcttttgaa agaaggtgat attatgccgc aaccagcgaa gagtgcaaaa ttacaattat
     1321 taaacggaaa cccaaataag aagaataccg aagaactccg caagcgagcg gccgcagaag
     1381 acaaattaaa aatggctact gacaaaatca aaccgccgtt atggctagat tcgctaggaa
     1441 aggatacctt tgagtttatc gctgatgaat tgctgtctgt ggatttaatc agtaatccgg
     1501 acgtccatac aatggctctc tactccaatt ggtattcgca atacgtttct ttagaaaaac
     1561 agcttcgaaa actacaacga gagtacaagt tgaactatgc gcttgcgaaa aaggaggcag
     1621 aggcgagagg tgagccgttt aatgaaccta atgaattaat tggtaatccg ctctctcggc
     1681 agatggatac agcgtcgcgg aatctccgtt cttttggcgc tgatttagga ctatcaccag
     1741 cagccagagc taagttagct attaagatgg ctgatgatgg tggtgatgac gatgacgact
     1801 tctaatattt tggatatgtc ctacacagaa cgtgtggact attggcaaag ctatcttgag
     1861 gagcaagctt cttggggtgg ctttttaaaa tgtccatatc cggaattgtt aactacttgg
     1921 tatgcggaac gattaatcga tggaagcata ccagccagca aagaaaatat tcaagctgct
     1981 aaacggcata tgcgtgattt gcagcgccaa ggaacagatg attttccttg gatctttgac
     2041 gaagaaaaag gtcaccggcc tattagatat atcgaaaaaa aatgtaaacc aactgaaggc
     2101 gactttggtt cgtttgtttt gcaaccttgg cagcatttca taattggatc catgtacgga
     2161 tgggtacatc gtgatacagg agagcgtcgc ttccgcgagg ctcttatttt tgttggacgt
     2221 aaaaacggta agttttgccg tttaaaaatc gggcaaaatc ggtgaaaacc tttatttttg
     2281 gctttctttt agtaataatt cgatagcttt atcaagcaat ttagacatag gaaccatagt
     2341 ttcttccgac atttttttta atccttcgta taaatcttta tcaattgcgt tagaaattct
     2401 aattctgttt tttagtccgt atttgtccat gtgtgacact cctttttatt ttactataac
     2461 atccgattcc accgcttgca
//
LOCUS       DADVXK010000191         2447 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.199, whole genome shotgun sequence.
ACCESSION   DADVXK010000191 DADVXK010000000
VERSION     DADVXK010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.199"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..141
                     /locus_tag="KB909_002836"
     CDS             <1..141
                     /locus_tag="KB909_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6838788.1"
                     /translation="KRLVLENELTYTEIADILGFHSIHHFSSAFKKYTGLSPSKYYLS
                     LK"
     gene            282..1895
                     /locus_tag="KB909_002837"
     CDS             282..1895
                     /locus_tag="KB909_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6838789.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT          774 a          433 c          464 g          776 t
ORIGIN      
        1 aaacgtctcg tgctagaaaa tgaattaacc tatacagaaa ttgcagatat attaggattt
       61 cattcgatcc atcatttttc ttcagctttt aaaaaatata cagggttatc cccttcaaag
      121 tattatctat ccttaaaata gaaaaaaatt tttaggtttt atccacaaat tatttctcta
      181 tattttctgt ctattcaaaa taaacaataa ttttccggca caattatttg ctgtttttta
      241 ccataacata gtacgatcaa cgtagaaaag gagatgtttt tatgaaagtt gttgtcattg
      301 gcggtgtagc tggcggtcct tcatttgcca ctcgtttccg tcgattgaat gaagcgcacg
      361 aaatcattat ctatgaacgc ggagaaaata tttcttatgc aagttgtgct ttgccttatt
      421 atttaggagg tgtgatcact gaccgtgact cgctgatcga acgtacacca gaaatattga
      481 aaacaaaaaa caacatcgat gtctttacta aacacgaagt aacagcaatc gatccttcta
      541 ctaagcgatt aacagttaaa gacctatcca caaatgaaga aataaaaaca gattacgata
      601 agttgatcat ctcttctggt gctagaccag attatccgga tattcccgga gtttttgaag
      661 cagaaaacgg ctttgtcctc cgtagtgtga cggatgcgga tcgaatcaaa tcgttccttg
      721 aagaaaaaaa tccacaacat gtcgtcattc ttggtgcagg tgttatgggt ctggaattag
      781 ctgagaattt caagcatcgc ggcttagacg tgactttaat cgatcaattg ccacaagtcg
      841 ctttccctta tgatccagaa attgctaatt tagtttatga caaattgctg aaagaaggat
      901 tagccgttca tttagaaaca agagttactg agatccgtga taaaggtcga gaaatagtat
      961 tatcagatgg ctccgtcctt tctgctgata tgctaatttt tgctgttggt gtttctccga
     1021 agaatgaagt ggtgaaagca accggcatac aattatcaga tacaggtcag atcattgttg
     1081 atgaccagtt acaaaccaat ctgccggaca tctatgcgat tggcgatatt atcgaaacga
     1141 ctagtgtagt gactggtcag ccgatccaaa gtatgctttc cagtgcggcc aatcgtcaag
     1201 gacatatgct ggcagatatt ttaaatggta cgcctatgcg ctatcgcgga tatattggtg
     1261 caggtgtcgc aaaaatcttt gatcatacag caagttatgc gggaatgaca gaacatgaat
     1321 taaaagcatc aggcataaca aattataaaa ctgtttttat cactcccttt gaccatgcct
     1381 atttctatcc agaagctaca agattaaatc taaagctgat ttttgatgca gatagcggtc
     1441 gtattttagg tggacaagca tttggagaaa aaggtgtcga taaacggatg ggagaacttt
     1501 ctgtagcaat caccggaaac ttgacagtct ttgatttgcc tgatttggag ttgccttact
     1561 ctccaccgta ttctactacc cgtgacccgt tgaatatagc tggttatgtc gcaatcaatc
     1621 aaatgacgaa tatcgtagaa acgatcaaag caagtgatat acccgaaaac gatttgaaag
     1681 aagcgttctt tttagatata cgtgaaccta ataaagcacc ttctggcagt atctcggcaa
     1741 caaaaaatat tccaatgaat gagttacgag atcgaatcaa tgaaatccca aaagataaaa
     1801 aagtttacat tactttcaga agaggattga atacttatac ttctgcccga atcttggcag
     1861 gtttgggtat caaagcgatt ttgattgaag aataaaaaaa cgaccgcggt gggtagccgc
     1921 ggtctaggag ttatttttac ttgaggagta aaaatgaaaa agtatatagg gttgttggtt
     1981 ggtatgtata tagaatagaa gataaatgtg aagaaattgt gcattatttc ttcacattta
     2041 ttaggttata gtttaagaaa gtttaaacat tgcgcaattt aattatttta gctgtttctt
     2101 ttcataaaaa aacatgttgt gactctgaga caaatcatag tccatagtga tgtctctaga
     2161 gtaactacgc ctaatattac gaggcatcat attaatctat cagcactagt acctaaacta
     2221 gcatcccttt cgaatatttt ttcttatata ataaagtttg ctttcactcc tctaatctca
     2281 ccaaatcgac tggcttgcgt tgtgtgatac taggaactga ttggtttaga acgacttttc
     2341 tattgtaatc atatttttcg ccatcctcgt tgtcttctaa tccttcaatg aatgatccct
     2401 aatgtgtgta ttaaataatt taattttttt gttcctattt atttaac
//
LOCUS       DADVXK010000192         2398 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.200, whole genome shotgun sequence.
ACCESSION   DADVXK010000192 DADVXK010000000
VERSION     DADVXK010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.200"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            207..2069
                     /locus_tag="KB909_002838"
     CDS             207..2069
                     /locus_tag="KB909_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6838790.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="KB909_002839"
     CDS             2069..>2398
                     /locus_tag="KB909_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6838791.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DADVXK010000193         2341 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.201, whole genome shotgun sequence.
ACCESSION   DADVXK010000193 DADVXK010000000
VERSION     DADVXK010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.201"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            38..2191
                     /locus_tag="KB909_002840"
     CDS             38..2191
                     /locus_tag="KB909_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBB6838792.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          806 a          415 c          523 g          597 t
ORIGIN      
        1 aatgaagcat gaatgtaaat aggcggaagg ataggaaatg atgaaagatt ttatgaaaaa
       61 aatattaaat acttcttggt tagaaaaaat aagaaaaggt gcacaagaac ctaagaacaa
      121 aacgtttcgc cggtcccatg ttccttttcg cttaaatttt ctttttttca ttatatttac
      181 gttatttgtt gcgttgattg ctagattggg ttatttgcag atcgtgaacg gcgaagagat
      241 ggaggcgcga gtgaagtcta cttctacgat tacggtccaa gaaagtactc ctcgcggaat
      301 gatctacgac tccacaggaa aagctttagt tacgaataaa gcgaatcagg ccatcacata
      361 tacgagagga acacaagtta cggctaaaga tttgcttgaa atcgcaacga agctgaactc
      421 gctgatcgat gttccggtag atgaaaatct gacagataga gataaaaaag atttttggct
      481 ggctgatccc aaacatttga aagaagccac aaaaagactt tcggcaaaag aaaagcaatt
      541 agggaacagc gaacaatata gtgcgatggt caataaagtc acagctgatg agattaattt
      601 aaacgaggag caattaaaaa ttgctaccat ctttaaacgg atgaatagtg catatgaatt
      661 aaacactgtc tatatcaaaa actctggtgt tactgatcaa gagttagctg ttgtggcaga
      721 acgcgcttct gaacttccag gagtttcgac tggcacagac tggacacgag aatataatgc
      781 agcaagttca ctgaaaagta ttcttggcag tgtgacgact gaaaagcaag gacttccagc
      841 agatgaagca gagaaatacc tagcaaaagg ttattctcgg aatgaccgtg taggacaaag
      901 ttatttggaa aaacaatatg aagatgtcct gcaaggaacc aaaacccaat atgaagtttc
      961 ccttgataat gaaggaaatg tttcgaatca aaaagaaatc ttctctgggg aaaaaggttc
     1021 taatttaatg ttatctatga atgcagaatt ccaatcaaaa gtagaagaaa ttttgaaaag
     1081 gaattatcaa acattgatca acaacggcaa agcacagtat tcgcctggtg cttatgcagt
     1141 ggctatgaat cctcagacag gagaagtgct agcaatgact ggtttcagtc atgaacaagg
     1201 ttccaaagaa atcaccgaga atgctttagg cacgattact agcgcctttg atccagggtc
     1261 tgtagtcaag gctggtactt tgacagcagg ctgggcaagt aacgcgatca gcggaaatca
     1321 agttttgatt gatgagccga ttcgtctgca aggtgcttca gaaaaaagct ctgtctttaa
     1381 tcgaagcgga caagttgctc ttgatgcagt caaagcatcg gaattgtctt ctaatacgta
     1441 tatgatcaaa gtggcgttaa agatgttagg actagactat acacctggaa tgggactacc
     1501 tagtttagat gaagaagcta aagcttatca gcaattgaga gactctttca aagagtttgg
     1561 tcttggtaca acgactggga tcgatttgcc gaatgaatct cctgggatct cacgttctgt
     1621 tgattatatg aagaagttca atgcggataa tggcaaagaa tggtatgctc caggtaactt
     1681 taccgatttg gcatttggac agtttgacac atatacacca atccaattag ctcaatatgc
     1741 ttcaacagtc gctaatggcg ggaaacgagt acagccgcac ctagtcaaag cgatctatgg
     1801 caatgacgaa aatggaaact tgggtgaagt gaagaaagaa attggcacaa cagtagaaaa
     1861 tacggtcaat atttctgcag aaaatatggc gatcctccgt gaaggattcc accaagttgt
     1921 ccatggtacc gatccttaca caacagccaa accattagcc agtgcgaaaa tggacctttc
     1981 cgcaaaaaca gggactgcag aaacggttgc ggaaggtcat ccagatattg cgacagtcaa
     2041 tagtaatatc gtggcatacg gaccaacaga caatccggaa attgccatca gtgttgtctt
     2101 gccgaactta ttagacgaac aagaccacat aaacttgacg attgctaaag aaataatgga
     2161 cgcgtattat gatatgttca tggcaaaata aaaaagaggt cgtgaaaaag ccgcttagtt
     2221 tcgagtatga agaaaaattt tgtgaaaata gcttctcaca tttttgctta aatttgactt
     2281 cataccgaga aactggcttt tgaacaccgt ttactcggca aaaaaggttg tgacaaaaat
     2341 t
//
LOCUS       DADVXK010000194         2315 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.202, whole genome shotgun sequence.
ACCESSION   DADVXK010000194 DADVXK010000000
VERSION     DADVXK010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.202"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            142..1989
                     /locus_tag="KB909_002841"
     CDS             142..1989
                     /locus_tag="KB909_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBB6838793.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            1992..>2315
                     /locus_tag="KB909_002842"
     CDS             1992..>2315
                     /locus_tag="KB909_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoesterase"
                     /protein_id="HBB6838794.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTK"
BASE COUNT          866 a          289 c          465 g          695 t
ORIGIN      
        1 gggaattatt tggttacgag tcgaggggtt tttgaactaa tgtaaatcat ttgttagaat
       61 tgaccagaaa tttctatcgt acttttactt ttctatttga tatactgaaa tagaaaatat
      121 ttgttgatag gggtgttact aatggttggc aataagtggt acaaatgtga tcttcatatt
      181 cattcaactg cgagtcagtg ctttcaggat aaaaaggtta ctgctaagga atgggtagaa
      241 gaatgtttaa acaaaggact cgattgtgtt gcattaactg atcacaatac aggggaaaat
      301 attgatgaat ataagaaagt ggctatcgaa aatggcttag atttttttcc tggagtggaa
      361 ttaacgtgtg gagaaaatgg aactcattta ctagtcctat ttgataaaag tgcatgtaca
      421 aatgatatct ctgatttctt aaccaagatg ggtataaaaa gagaggattg ggccagcgct
      481 gcagcttgct caatgaaatc agttttagaa gttattgatt ttgctgagca cgagggcttg
      541 ctcgttattc ctgcacatat agatgagttt aatggaattt cttcagcaaa atttggaaat
      601 ctaggaaaga tatttgaatc agaaaatata tatgcagtac agacggttca aaaagaattt
      661 tttgaaaatc gctcacaaat gattccctca tctaagcgtg acactatcta tgatagtgtg
      721 aatgccagat atgatggtag agttggaaaa gatactttgg aatcttggta taaatcagtt
      781 gttgaggcag aaaaaaataa tatgacattt cttagctttt ctgataaccc acactcgaaa
      841 ggaaattcaa aacatggact ttggggaata ggcacaagat attcctatat aaaaatgaag
      901 gacgaacctg acttgggatc acttcgcgat gctttaatgc taggcgaaac tcgagttcat
      961 tctgattttt ctaatttctc cattaatgaa aatgaagttt tattggaaaa attaagcttt
     1021 tctgggacca ctcttagcac aaaagaagtt gtagtcgaat tcagcgataa tttaacttca
     1081 attattggag gaagaggaac aggcaaatct tgtattacaa gattcttggt ctatgtcctt
     1141 ggaaaggaag cagaacttga tcaattttct gaaatacaaa gtgattatca gaactttgca
     1201 caaattgaac ataatggctc tggaatattt ttgaaggata caattgtgaa actgaatatt
     1261 ttctataagg ggacaaaata tcaaataata agaacacagg atagacattc tatttatgaa
     1321 tttacacaag agaatggtct ggttgaaaaa gaaacagaac ggttgagaat gatttccgat
     1381 aaggtgagta tatactctca aaaacaaatt tatgaaattt caaaaaatca aactagtata
     1441 ctagaattac tagatggata taactctgat ttgatttcag agtataaaaa tgagattgaa
     1501 acatgtgtaa acgaaataag aaaattaaat tgggatattg tttctgtgaa aaaagaaata
     1561 caagataagg cgaaggtaga gcttgaaatt gaagatttaa aaaaacaagt agaaaagcta
     1621 tctcataaga gttataaaga tgtttatgat gagtattcaa aagagacaga tatttatagg
     1681 gaactgaaac gtgatgtgga ggcacttaag gaaattccca aaaatctaac tgatagtgtt
     1741 gacaaaattg actttggcaa tggtataaaa gttacagacg aaattgatga acaccgcgga
     1801 gaattgatta agaatttagt gaccaatcgg gctaagattc aaacaataat taatgaaatg
     1861 tcagatgaaa ttgatagtta tagagcagag ctgaataaat cagattggaa agttaactat
     1921 aatgaggttt caaagaggta tcaaagaggt atcaaaaact tagtgaagag ttatctcaag
     1981 atgaattaaa aatgttacaa aaccttgatt ctttatatca atctttatca aaaactgaag
     2041 agcgattgga agaaattatt caacaagaaa taaagcttaa agattaccaa gttgaggttg
     2101 actcagcaat gtcaagaatg aataaatcat atcaaaatct ctattctgag agaagtagtt
     2161 cctcgcgcga aattttttct gatattacag gaatagaggc tactattcaa ccaaataggg
     2221 atttcaataa ttatgttaaa gagctcagag cttgtattaa taaggaggac acttttgaca
     2281 gtgagtttgg atctcttatt gataagctga caaaa
//
LOCUS       DADVXK010000195         2275 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.203, whole genome shotgun sequence.
ACCESSION   DADVXK010000195 DADVXK010000000
VERSION     DADVXK010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.203"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            86..1435
                     /locus_tag="KB909_002843"
     CDS             86..1435
                     /locus_tag="KB909_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838795.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="KB909_002844"
     CDS             complement(1563..2153)
                     /locus_tag="KB909_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6838796.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
BASE COUNT          670 a          435 c          436 g          734 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta ctttt
//
LOCUS       DADVXK010000196         2184 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.204, whole genome shotgun sequence.
ACCESSION   DADVXK010000196 DADVXK010000000
VERSION     DADVXK010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.204"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            94..969
                     /locus_tag="KB909_002845"
     CDS             94..969
                     /locus_tag="KB909_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838797.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(1114..1266)
                     /locus_tag="KB909_002846"
                     /pseudo
     CDS             complement(1114..1266)
                     /locus_tag="KB909_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(1534..>2184)
                     /locus_tag="KB909_002847"
     CDS             complement(1534..>2184)
                     /locus_tag="KB909_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6838798.1"
                     /translation="TIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDP
                     FLIQNMQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKD
                     FAKLSVTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVV
                     QIPWTTPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
BASE COUNT          770 a          393 c          349 g          672 t
ORIGIN      
        1 aaagtgatta tcaaatatgt aaaatcagct acttttttct taaacgtttc tttatactaa
       61 atataaataa gtgtttcatg aaaggagaac tagatgaata attggcttga gtattttcct
      121 gaaaacgttt tggaacgcgg ttacagctat catctgcacg gttttgtccg tcatttgaac
      181 tatacaagca agtacttgtc cgcaacagtt tctggcacgg aagattataa ggtagtgatc
      241 acttgggatg aaaagaccaa catgacttgt gattgtctat atgccataga aggaaaaaaa
      301 tgcaaacaca tggctgctgt cttattcgct tacgaagaac gtccaataaa aaaatccaac
      361 tactcacttt ccgaactctc gtcccttgtt tcctccgcta gttcctctct tgtacgggag
      421 cttttaacag agattcttat agaacatccg caatttatcg aacgcttcaa agttaagatg
      481 ccatttcatg caataaatta ttcagataaa ttaacaacta tcatccataa atacgatcat
      541 attatcaaga aaaacaaaaa caggaaaaca gcgaagttca tcatggagat gcgaaagttc
      601 atccaagaag cagttgaatc gctcattcag caaaatgcct atcttcccgc attcgaattg
      661 atcaatgaag tgattgctac tctcgaaaca ttctattggg agcctgagga tgaacgaacc
      721 cttcttctga tagaggactg ttattattta tggaaagaat tattagcaga agcacctcat
      781 gcagaaaaaa ggcaaatgtt ctcttggttc gtctgccaag tcgatcatac tgacgcctct
      841 tattcaaaac gctactccat aaaaatcctg aaagaagact ttcgggaaaa agaattttct
      901 aaccaaaaga aaaaaataga taaaaaaact aaagaaacgg taaagaaaga cgatttcaat
      961 gaaaaatagc aagtaaacga taacaaccat cctaaatcca caagaaatac agcagacctt
     1021 gctttaaaaa cacgaatcat gcaaaggatg aagtaaagaa gacttaacgc gtacccaata
     1081 ttagtcattt gactattagg tacgcgtttt gttttataag tcatgacaaa tttccttcgt
     1141 tgctgggtag attttccggc attgttgata gattttatga tacttttcta cattttgtaa
     1201 gagaggttcc actgcatctg tatattggat aaaattctga caacaacttt caggtgtgtc
     1261 gaaccactct aatctttaaa gataaatatt aaaataacga ttaataatat taacagtctt
     1321 tatttttcac caccaaaaac ctatctttgc atatactaaa tagacgtata tacacagata
     1381 ggtttgtctt gtgaaaaata atgattatcc ttaccaaaaa atgtttgttt ttctacatgt
     1441 tcgtacttat caaaaaatat gatccttatt gaaattactg gctatttata ttccaacgac
     1501 ttcttgtgtt aatttttgtt atctcatagt aaattatgtt tcattttcac ttaatttagt
     1561 tgtcacgtgt tcgtcaattc gtaaaaacgg taaatatata aacacacttg cggctataat
     1621 taatatttgt aaaacagctg ctcgccagtc tccggctgtt gctaaaaatc ccgatataac
     1681 tggtggcgta gtccaaggaa tttgcactac tacatgatta attaatccca cagcagttgc
     1741 aaaatatgct actgtcaaag aaaaaatcgg tgcaagcaca aagggaataa tcagactgat
     1801 attaaataca ataggcaatc caaaaataat aggttcgctt atattgaata tagcgggagt
     1861 taccgataat ttagcaaagt ccttataatc ttttctacga ctgaagataa atattgcaat
     1921 caataaagca atcgtatttc ccgatccacc cattaccgca aaggtatctt taaaggccat
     1981 attgataata tgtggaattt gctctttgtt tgcataagct gccatatttt cttgcatatt
     2041 ctgaatcaaa aacggatcta acaatgaacc tgatattact gcttgatgga taccaaatcc
     2101 aaaaaataga ttagcaatag atgtaattaa caaaaatcct ggtaaaccag ttgtaatttt
     2161 acttaatggc tctgtaacta tcgt
//
LOCUS       DADVXK010000197         2093 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.205, whole genome shotgun sequence.
ACCESSION   DADVXK010000197 DADVXK010000000
VERSION     DADVXK010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.205"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>2093
                     /gene="acm"
                     /locus_tag="KB909_002848"
     CDS             <1..>2093
                     /gene="acm"
                     /locus_tag="KB909_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBB6838799.1"
                     /translation="RNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVDPTNI
                     TDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTV
                     RKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTK
                     PASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPST
                     FEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVS
                     YKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIF
                     KYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEA
                     PNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFK
                     LFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVP
                     SGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEV
                     SEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPG
                     SHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKS
                     ILPKTSSKKSSFAVI"
BASE COUNT          823 a          343 c          404 g          523 t
ORIGIN      
        1 tagaaatatt attttatcaa tgttatttat tattactaat ataacatcac tgattcctgt
       61 tcatgtctat gcggatgcag gcagagatat cagcagtaat gtcacttcgt tgaccgtgga
      121 cccaacgaat attacagatg gaggaaacat aaaagtaaaa ttctcgtttg acgaaaaaaa
      181 acaaaatatc caaccaggtg attatctttg gatcaattgg ccaagtgaag gaaatattcg
      241 cggtgaagga ttccaaaaag aaatcccatt aatgattgaa aataaaaatg ttggaacttt
      301 aacggtcaga aaagattctg cgcaggttgt gtttaatgaa aatattaaaa acctagactc
      361 agtagaaggt tgggggcaat ttgagataca ggccagaaac gtaaccgata ccggtgaaga
      421 aaatacggga ccattcaccg tgacgagcgg tgataaaaca gctactgtaa atgtgacaaa
      481 gccagcttct ggttcttctt ctagcgtttt ttattataaa acaggagaca tgctacctga
      541 agatactaag cacattcgat ggtttttgaa tattaacaat aacggcactt atgttgaaca
      601 accagttaaa atcagtgatg aaatccaaag tggacaaaga ttagatccaa gtacgtttga
      661 aattaatcaa atacacttag gtgaacagaa ggtttataga ggagaagagg gaatccaaca
      721 atttttacaa gatttcccca gcgctacatt taatttttca gtaactgata attacattga
      781 aataactata ccaaaaaact ttgtcaatct taggaaaata atggtgagtt ataagacgat
      841 catagaaaac ccagaacaaa taaattttga gaatcattcg gaagcttggt ttaaagaatt
      901 taataaacct gctgttgatg gagaaagttt caatcataca gttaaaaata tttcagcttc
      961 tggtggagtc aacggtacag ttagaggcga attgaagatt ttcaaatata tcaatgacac
     1021 agagattggt atcccaaatg tgactttcga attaagacga gcagatgaac agcctattca
     1081 aggacagtct agtatcctgt tgacttcgaa tgaacaggga gaagctagta tcaaaggcct
     1141 gcaagtagga gactatgttg taaaagaaaa agaagcaccc aattggattg attttgatcc
     1201 actaagttca aatgaactca aattctccat aaacgaaaat gatacagagg gagtcagttt
     1261 acctatttat aacaagaaaa aggttacgaa catcacagca actaaaattt ggaacggtgg
     1321 aaccactcca agaccgagta tttattttaa attattcaga gcaagtacaa acaattggga
     1381 accagttcct gatgcagaaa caaaacgatt agacaatgga ataacttcag tgacttggga
     1441 agatatccaa cagtatgatg atagtggaaa cgaatatacg tttaaagtgc aagaagtaga
     1501 tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa attgaaaacg ggctagtcgt
     1561 tacaaatgag aataaagaag tcatttcagt ctcaggacaa aaaacatggg aagacaatga
     1621 gaaccaagac ggcaaacgac cgacgacgat cacagtaaat ctattagccg acggtcaacc
     1681 gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc tatcgtttca caaatctgcc
     1741 aaaatacaga gacgggcaag aaatcatcta tactgtaacg gaagacaacg tgcccgaata
     1801 cagtacgacg attgacgggt ataacatcaa aaacagttat acaccggaaa aaacaaatat
     1861 atctatacca ggtagccata taacaccgtg gaaaaatttt ccagagaaga cagagagaga
     1921 gaaaattaga aatctattct ctcaaaaatt gcaaatattt gctcatacag gagaatccag
     1981 cgaacaaaga agcaattata ttagtaagag agctgtacct aaacagataa caaataaatc
     2041 aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt tttgctgtaa tca
//
LOCUS       DADVXK010000198         2056 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.206, whole genome shotgun sequence.
ACCESSION   DADVXK010000198 DADVXK010000000
VERSION     DADVXK010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.206"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..187)
                     /locus_tag="KB909_002849"
     CDS             complement(<1..187)
                     /locus_tag="KB909_002849"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6838800.1"
                     /translation="METRDYIITHQKLIESGLSHFEKEGFQQTKIRQLCLTAGVTTGA
                     FYKHFTSKEALFEEIIQP"
     gene            complement(479..712)
                     /locus_tag="KB909_002850"
     CDS             complement(479..712)
                     /locus_tag="KB909_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBB6838801.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(727..1677)
                     /locus_tag="KB909_002851"
     CDS             complement(727..1677)
                     /locus_tag="KB909_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6838802.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(1674..>2056)
                     /locus_tag="KB909_002852"
     CDS             complement(1674..>2056)
                     /locus_tag="KB909_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6838803.1"
                     /translation="KELLITSFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGT
                     ILIVAMLITPAATAYLYANSLKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTA
                     AFLFVISFLISPKQKFLRKKERSL"
BASE COUNT          638 a          386 c          262 g          770 t
ORIGIN      
        1 gcggctgaat aatttcttca aataacgctt ccttagaagt aaaatgttta taaaaagcac
       61 ccgtagttac gcctgcggtc aggcacagtt gccttatctt agtttgctga aatccttctt
      121 tttcaaaatg gcttagtcca ctttctatta acttttggtg agttataata taatctctgg
      181 tttctatggg tacttcctcc taataagatg aattaacttt attatcttac acaggacttg
      241 aagtttcaat cgttaacgtt tattactgaa ctcattcctt agagctaaac taatgagaaa
      301 gagcagaata actgatacaa aaagcaatcc tacaagaatt aatagactca tctaaatcat
      361 tcaccttttc taaaataatc cgagaaagat ttaaaaaaat tatatccagc tattaggata
      421 agtcctatca taatcactcc aatagccatt ttcttatcct ccctaaaaat aaagtctttt
      481 acttaaaacc ttttttgtaa tcgtcaataa attttttccc tttatcagtt aattgaaatc
      541 ctatatctaa atagtcctca tatctaagtt tagccagcat ctcacttaca gatgctggac
      601 taacacttag aacttttgct aaatcattat tttttaattt cttttttctt tttgataatt
      661 cctgaattgc tagtaaataa attagtatag tagtcgtttt aatttgtacc atacctaccc
      721 tccaaattat ttcgaaaggc cttcagcaat tttatccagg ttccatttca tcatcgcata
      781 gtaactatca ccatcttgtc ctttttctgc aattgaatca gtaaaaatcg ttgaatagat
      841 aggaatattg gtatcttttg atactgtttt cattggtcta tcatccacac tgctttctac
      901 gaataaggag ggaacttttg ttgtgcgtaa tttttcaact aagtgtttta tttgatctgg
      961 tgttccttct tcttcagtgt tgatttccca aatgtaagca gaaggcacat tatacgcttt
     1021 cgagaaatat ttaaagcatc cttcacttgt aacaatcatt tttttatcat tcggaattga
     1081 agcaaattta gatttagctt ctttgtctag agaatccaat ttttcaatat acttatctag
     1141 attttcttta tagaattttt tattatcagg atctttttcc gctaactgtt tttcaatatt
     1201 tttagcgtaa ataataccgt tttctaaatt taaccaagca tgaggatctt ccttcccttt
     1261 ctcactctga ccctctaagt aaataacatc tatgccatca cttgctgcaa aatagtcttt
     1321 gttttcctct ttgttcgcat ttttaactaa ttttgtaaac caagcatttc ctccagtttc
     1381 caagttaaca ccgttataaa aaatcaaatc tgcttttgaa gttttttgaa catcttcagg
     1441 caaaggttca tattcgtggg gatctttccc aataggtacg atactgtgta aatcaatttt
     1501 atcttttgct atattttcgg taatatctgc taaaatcgaa ttagtaacta ctacttttaa
     1561 tttttcgttc gaagccactt tatctttgtc tttactattt attgaacatg ccccgaatat
     1621 aaaaagagca atcaaaatcc ccagacttcc cagtactgct ttccattttc tcatcataac
     1681 gatctctcct tctttcttaa aaatttttgt tttggtgaga ttagaaaact aattacaaat
     1741 aagaatgccg ctgttaaaac aatacttgat cctgctgcta tgttaaaact ataaccaata
     1801 aacaatccaa gcaatgatga acttgctccg actgttgcag aaataaatat catagttttc
     1861 aagctatttg catataaata tgctgtagct gctggtgtaa ttaacattgc aacaattaat
     1921 atagttccca cactttgcat agctgttact gctactaaag ttaatagaac catcaataga
     1981 taatgataaa aactgacatt catccctatt gcttttgcca ttaatggatc aaaagaagtg
     2041 attaataatt ctttaa
//
LOCUS       DADVXK010000199         2055 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.207, whole genome shotgun sequence.
ACCESSION   DADVXK010000199 DADVXK010000000
VERSION     DADVXK010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.207"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..302
                     /locus_tag="KB909_002853"
     CDS             <1..302
                     /locus_tag="KB909_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HBB6838804.1"
                     /translation="IGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEI
                     ETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            275..952
                     /locus_tag="KB909_002854"
     CDS             275..952
                     /locus_tag="KB909_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6838805.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            942..>2055
                     /locus_tag="KB909_002855"
     CDS             942..>2055
                     /locus_tag="KB909_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_066164118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBB6838806.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFV"
BASE COUNT          757 a          277 c          414 g          607 t
ORIGIN      
        1 tgatcggaaa ttcttcttct gggataattg aagctgcatc attcaaaata ccagtaataa
       61 atttaggaac cagacaaaat ggacgagaac aatctaaaaa tattataaat gcaaatctaa
      121 atgaaaatga aattgaaact gctttgaata aaatacaaga tcctcagttt ataaaaagct
      181 tgaaaaatgt taagaacatc tacggtgacg gcaacagttc tagaagaata acaaaaacat
      241 tgaatcaaat attgaatgat ggggaagata ttaagtggat tcaaaaacaa atagcttatt
      301 aaaatatact agtgatccat acattattat tggggctggc ggacacgcaa aagtcattat
      361 tgaaacctta agattagaaa ataagttaat atatggattt tttgatgata agcaaaataa
      421 aatgcaagat ctgaaatatc ttgggaaaat aaacgaattg aatagctggg cggatagcaa
      481 aaaaaaaatc tataaattta ttgtagctat tggtgactgt gtagtaagaa aaaagattat
      541 aaaaaaattg aatatgccaa gtgagcaata tggaatagct gttcatccaa gtgctatagt
      601 ggcaaaagaa atttcaattg gttatggaac tgttattttt gcgaatgctg taattaaccc
      661 agatgctgta attggagagc atgctataat aaacacaggt agcattgttg agcatgattg
      721 tagaattaat aactatgttc atttatctcc aggtgtatgc ttagcgggtg gagtacatgt
      781 aggtgtagga actcaaatag gaattggttc tcaatgtatc cagatgaaga aaattggatc
      841 ttggtgtatg ataggcgcag ggagcactat tgttaaggat attccctcac attccttagc
      901 ttatggcaat ccagctaaaa ttaagaaaga aggaattaat tttgaattct agaattttat
      961 tatcaagtcc tcatatggga ggaacagaag aaaaatatgt tgctaaggct tttaaagata
     1021 attggatagc gccattaggt gaaaatgtgg ataaatttga agaaagtatt acaaaatata
     1081 ctggttctaa gggcggagct tctgcgttaa gttcaggtac agctgccata catcttgcct
     1141 taagactgct taatgttgga aaaaacgata ttgtctttgc tccttcattt acttttatag
     1201 ctacagtaaa tcctatttta tatcaagggg ctgtaccagt gttcattgac tcagaaccta
     1261 atacatggaa tatgagccct gttgcactag agagcgcatt agaagaagct gaaagaaaca
     1321 accaattacc taaggcaatc atcgtagtga atttatatgg tcaaatggct gattatgaac
     1381 gaattttagc tattgcaaac caatttaatg ttccagtgat agaagatgca gcggaatcgt
     1441 taggttctac ttataaggga atttcgtcag gcttatttgg gacaattggg atctattcat
     1501 ttaacggtaa taagatcatc acaacctcag gtggaggagc tctagtgtct agtgataaaa
     1561 aatatgttga gcattcaaga tttttagcaa cacaagcaag agatcaagca ccgtattatc
     1621 aacatagcga aataggttat aattaccgtc taagcaatat ttctgccggt atcggacgtg
     1681 gacaaatgga agtattgaat gatagagtag ctaaacgaag agaaattttc aatcgatata
     1741 aggaagcttt ttctggaatt gatagaattg aaatgatgcc agaagtggat ggcatggtgc
     1801 caaatcgttg gttgtctact ttaacgatca atgattataa ttctattgat caagtagtta
     1861 acgtaataaa taaactaaat gaaaaaaaca ttgaaacaag agctttgtgg aaaccactac
     1921 atttgcaacc agtatttcaa ggggtaaaaa tgtattacca tgataataat cttagtgtgt
     1981 cagaaaagtt atttaatagc ggcttatgct taccttctgg aagtaatatg acagatagtg
     2041 aacaagaatt tgtta
//
LOCUS       DADVXK010000200         2036 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.208, whole genome shotgun sequence.
ACCESSION   DADVXK010000200 DADVXK010000000
VERSION     DADVXK010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.208"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..607
                     /locus_tag="KB909_002856"
     CDS             <1..607
                     /locus_tag="KB909_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBB6838807.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELGMICGKLDRQYYSASAISSIVIPPK"
     gene            620..1528
                     /locus_tag="KB909_002857"
     CDS             620..1528
                     /locus_tag="KB909_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBB6838808.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1528..>2036
                     /locus_tag="KB909_002858"
     CDS             1528..>2036
                     /locus_tag="KB909_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838809.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          699 a          278 c          460 g          599 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtatgatttg
      541 tggaaagtta gatcgacagt attatagtgc aagtgcaatt tcttccattg tcataccacc
      601 aaaataggga ggtgatttaa tggcaaagtg gaatgtcata ttaagtacaa cagaacccta
      661 taattacgtg gggatgattc aagttcgaca aggcaataaa aacactgaag ttatggaagc
      721 tacaattgtc gaaaatggtc ttccatatga tttatcagaa tgtaaggtat attttgaatc
      781 agttgttggc ggaaaatatc cagtccaatt agaaacaaaa attgtggatg ctaaaaaagg
      841 gaaaatcaaa tatatttttg ataaatattc catgcagtgt ttgcatcgac aaacagccaa
      901 tttcattata tttaaaggag aagacttgat tggaacaact caagacttct cttattttgt
      961 catcaatgct gtttcaaaaa cagaaggaga aatgggttct tattggcaat caattgaaga
     1021 tttaattgct gatatgacag attttattaa tgaaaataaa ggcgatttta cggactggat
     1081 gaatgaaagg aaagaagaat ttgatcgctg gagagaggaa caggagaata gtttccaaga
     1141 ttggagagaa ggacaagaat cagattactt gtcatggttt gaatcaatca aggatatttt
     1201 gaagtctatc gatccaggtg gagtaatgtt agccgaatta atggatgcac gtgtagatct
     1261 tcaaggtgta cgccatgaat cgatttctga acgtttccta tccgatctaa attatttgta
     1321 tcaaaaaatg aaagcagcac ttttcacgat tgaatacggt gaaattgaag tgactgatat
     1381 tcttcaagac gatctctttt cagataatca cgaagtcgaa aaaattgaaa cagtagaatt
     1441 tccaattgaa gaaggagctt tgattattgc aactgttgat gatccaaaac agaatgtttt
     1501 cactcttgag aaagttgggg tgatttgatg gttaaagtaa agagaatgat ggaaactgat
     1561 gaatctggtg ttaaacgtca atttatgcca attacacatg tctctgcagt tttaggctta
     1621 gaaaaaatga tatcaggaca atcaaaagtt ctttcggtta atggtaaata tggtgcagtc
     1681 attttaacga aagctgattt aggattagag aatgcaatta ctgaactacc ttatgcaagc
     1741 gagacaagcg atggtattct tactgctgaa atgtttcaaa agatcgtaaa tggagaaggt
     1801 ggaacatata ttttgccgat tgctactcct gaacaattag gaggtataaa agttggggaa
     1861 ctcttagaag ttactgaaga aggtgtttta tctgcaacta agcaaacaga cttcaatttc
     1921 tctgaagaat taaaaggaaa attagaatct ctaaaaatat taaaagcagg tgcaaatata
     1981 tcaattgcag aagatggaac aattagttct acaggtggta gtgggactgg tggtgt
//
LOCUS       DADVXK010000201         1967 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.209, whole genome shotgun sequence.
ACCESSION   DADVXK010000201 DADVXK010000000
VERSION     DADVXK010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.209"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            63..629
                     /locus_tag="KB909_002859"
     CDS             63..629
                     /locus_tag="KB909_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6838810.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            774..861
                     /locus_tag="KB909_002860"
     tRNA            774..861
                     /locus_tag="KB909_002860"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:806..808,aa:Ser,seq:cga)
     gene            1195..1761
                     /locus_tag="KB909_002861"
                     /pseudo
     CDS             1195..1761
                     /locus_tag="KB909_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
BASE COUNT          693 a          303 c          381 g          590 t
ORIGIN      
        1 aatgctaaaa atagggtaca ataaaacaac atatactgca gtaaagaagt gggggagttt
       61 taatgagaag aaaagtctat accaaggatc aaattctaaa agctgcttat gatgttgttg
      121 caaaggaagg gtttaaagga tttactgcga gaaatattgc taaaaagatg gggatttcga
      181 cacagccgat ttatctggaa ttcaaaaaca tggaagattt aaaaaatacg ttgctggatt
      241 ctatctttga acaactaaaa gaagatgttt tccctattga acgtactggt gataaaatca
      301 ttgatctcgg tttgaactat atctactttg caaaaaagca tcatagtctt tacatggcat
      361 tgtacattga tgaacatggg gacggaaaga aaatgcatga tttttcatac aattatttcc
      421 gtgaaatagt taaagaagat gaaagataca atcaattatc ggatgaatat gtcgatgctc
      481 tgcatactgg tacatgggta gcagtgactg gcttagcgtc attgatgtca tcaaacatca
      541 tgcatccaac agaagaacaa atcattgcac tgatcaaacg gacaattgac tcgattttag
      601 cattagataa tcctgaaata atcagatagt gttctatcag tatgaatttg atcggtaagt
      661 ccgttggctg caaactgtca atggactttt ttgctaaaaa aagcgatttc tgttatttat
      721 ctattagaaa taggcttgac atttcgtgaa aaaagtttaa aaatagtact tacggaaggt
      781 tggcagagtg gtaatgcacc ggactcgaaa tccggcgaac cggctaatac cggcgcgcag
      841 gttcaaatcc tgtaccttcc ttatatcaac gattagaggt tgtgaagaag ctgtcctgca
      901 tcaagtaata agaacggcca aacaaaaata gcttttccta ttttttcgtt tgattgggct
      961 tattaccgca gatgcaagct tttgaacacc gtttgttcgg aataaggggc tgtgacaaga
     1021 cttttgtcac agccccttat tgttgtactt ttaacctaca atattttttg attccccctg
     1081 agtactattt tttataaatg ctagtaaatc aatcttcttt ggcctttttt tgataaaaaa
     1141 aatactagat gtaagataaa agtgtaaaaa cgatttgttt taggagggga aacgatgtgt
     1201 accgcaatca cttatgcaac gaaagaccat tattttggaa ggaattttga ttatgagatg
     1261 tcttataatg aagtggtcac tattactcca agaaattatc gtttcgattt tagaaaggta
     1321 aaaaatttag ataaacatta tgcaatgata ggaatagcag ctggggtatc caactatcca
     1381 ctctattatg aggctacaaa tgaaaaaggg ttgagtatgg caggactgaa ttttcctggc
     1441 aatgctgatt ataaagaatt acaagaagga aaagataacg ttgcaccatt tgagtttatt
     1501 ccatggatac tagggcaatg ctcaaccata gacgaagcta aagaattatt ggctactatc
     1561 aatctagtca atatcgattt tagtgaaaaa ctacccttgt cacctttaca ctggttatta
     1621 gctgataaag aaaaatcgat agtaattgaa agtatgaaag atggacttca tttatatgat
     1681 aatcctgtcg gtgtgttgac aaataatccg ccatttgatt atcaattatt taatctgaac
     1741 aattatcgct cgctatcaaa tggaacgaga gtataaaata ttttgtgtaa atgaaaaaat
     1801 ccatacaaaa aaggaagtcc cttctgtaga ataaagttaa cgacaaccaa ttcacagaaa
     1861 agaggacttc cctatgaatg attttactac tgaatcggct acactagact agacagaaaa
     1921 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatg
//
LOCUS       DADVXK010000202         1859 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.210, whole genome shotgun sequence.
ACCESSION   DADVXK010000202 DADVXK010000000
VERSION     DADVXK010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.210"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            416..1804
                     /gene="ltrA"
                     /locus_tag="KB909_002862"
     CDS             416..1804
                     /gene="ltrA"
                     /locus_tag="KB909_002862"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6838811.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT          654 a          343 c          444 g          418 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag ggatcgataa agcgaaagcg tatgaatggt caaatacaag
     1681 aaaaggtatt tggtcagtct ccaaaagtca tattcttcat cgatcattaa cagacaaaga
     1741 actggcccgc caaggatatg aggacatctc cttgaagtac cagttcgtac actcaactta
     1801 ttgaaccgcc gtatacgggt ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DADVXK010000203         1830 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.211, whole genome shotgun sequence.
ACCESSION   DADVXK010000203 DADVXK010000000
VERSION     DADVXK010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.211"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1350
                     /locus_tag="KB909_002863"
     CDS             <1..1350
                     /locus_tag="KB909_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6838812.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..>1830
                     /locus_tag="KB909_002864"
     CDS             1484..>1830
                     /locus_tag="KB909_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6838813.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQ"
BASE COUNT          733 a          264 c          379 g          454 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat
//
LOCUS       DADVXK010000204         1759 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.212, whole genome shotgun sequence.
ACCESSION   DADVXK010000204 DADVXK010000000
VERSION     DADVXK010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.212"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..569)
                     /locus_tag="KB909_002865"
     CDS             complement(<1..569)
                     /locus_tag="KB909_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6838814.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKN"
     gene            complement(580..1248)
                     /locus_tag="KB909_002866"
     CDS             complement(580..1248)
                     /locus_tag="KB909_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6838815.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1378..>1759)
                     /locus_tag="KB909_002867"
     CDS             complement(1378..>1759)
                     /locus_tag="KB909_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6838816.1"
                     /translation="LENIDIEKSWRENFNELDPFINYIFENKRIFDLILFQSAGTKYQ
                     DIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYATFYDILKHSYS
                     KEKTMLLTRRLYQFSVPGWIELLS"
BASE COUNT          635 a          292 c          230 g          602 t
ORIGIN      
        1 ttatttttta aatcacaaag taagtcagca agtttcttag tcgctttgaa gtccaaattt
       61 gaagacggtt catccaatat aattaattta gagtttagcg ataaactaca tccaatagaa
      121 attttctgcc gttcaccact tgatagcgaa aaaatgtttt tatctaatat atttgaaaga
      181 tctaataatt cagctaattc attgattctt ttatccatat gctcttttgt aaatccaaag
      241 ttttccatcg aaaatactaa ctcactcgtt gtatttgttg taaagaattg tcctctagga
      301 tcttgactta cgtagccaat attttttgat atactttctt gtgttaagga ttgtagcgag
      361 ttattttcaa ataaaatttc cccaaccaat tttccgtcat aaagtcttgg aataagtcca
      421 ttcattaact ttaatagtgt ggatttccca ctcccagaag aaccagtaat caatgtaaga
      481 ctgccttttt ttattgaaaa attaaggtca acaagcgctt gttccttaac atccttatat
      541 gaaaaagaaa cattgttaaa ttcaaacaat tctttcacct caaatcaaaa tacttaagaa
      601 aaaaatagta acggaaaaca ggatgatata gtctaataag ctcatgtttg ttttatagta
      661 agaacttctt ttcacaggag attctatccc ctttgttatt gcattagcgg tcatttcttc
      721 agcaatcata gttgcacgta taagaacggg aactaacaga aattccaaat attgcagagg
      781 ctgaaaaaaa gacaagcgaa tgtttctcat ttttaaagat tctttaatca ttcttatttc
      841 agaacgataa gtcggaaaga atctgatcac tactgtaata cttaacatta tttttttcgg
      901 taaatgtatt ttttctaaag aggataataa ttcattgcta gtatagacac taaccaacaa
      961 ccatgagatc attacgaccg gcaacattcg aaatacaata tataaggatg tcgcaaaaaa
     1021 tatagtaaaa aactctatct tgatagcatc aataattttc attactaaaa acagaactga
     1081 ataaatcaag atgaaataaa tacatgtctt tattttacga aacatcaata ctaaaactgt
     1141 agcaataatg aaacacccca cttgaaatat atttcccttt cctaaaaaaa taatgaccgg
     1201 aaaaaaaata tttaaagtaa tcaaggttaa cggattgatt tttgacactc tttcacctcc
     1261 aaaaaataag atcgcactgt tatcttaagc tgataaaaat gcaccgttat tcagataaca
     1321 gtgcgatctt atcaaaaagc ataactgaga acaattctca atgcaagctt tttttaatta
     1381 actcagtaat tcaatccacc caggaacaga aaattgatac aatcttctgg ttaatagcat
     1441 agtcttttct tttgaatagc tatgcttcaa tatatcatag aatgtagcgt agaatgagta
     1501 aatgtagaag tggatttctt cttcattaaa gactaaattt tgattgatca ttccgatagt
     1561 ctttaactta tctagacaac agactgtctt tttcgtcaca aatgatgtaa ttttttcaac
     1621 aatatcttga tatttggttc cagctgattg gaataaaatc aaatcgaata tacgtttatt
     1681 ctcaaaaata taattaataa atggatctaa ttcattgaag ttctctctcc aacttttctc
     1741 tatatctata ttttctaag
//
LOCUS       DADVXK010000205         1749 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.213, whole genome shotgun sequence.
ACCESSION   DADVXK010000205 DADVXK010000000
VERSION     DADVXK010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.213"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(416..>1749)
                     /gene="brnQ"
                     /locus_tag="KB909_002868"
     CDS             complement(416..>1749)
                     /gene="brnQ"
                     /locus_tag="KB909_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6838817.1"
                     /translation="KDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWANLGFLVT
                     GIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPRLATTSFE
                     IGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLVLLGALLL
                     LAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTIQNMGVTK
                     PAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIADHYLGTY
                     GSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLAANVGLTN
                     IIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDGLNACPET
                     IKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD"
BASE COUNT          617 a          347 c          305 g          480 t
ORIGIN      
        1 ttttgcgaaa actattttta tatcatatat atgtctaaaa tctatattat aaaagaaatg
       61 ttgtttgatc agcttctctt cggtattagt tcaaaacaaa acggcaaagt atatggagct
      121 actttgccgt tttgtttctc taatactcag gtcagtttat agacgctcaa taaacggtgt
      181 tcaaaagcca gtttctcggt attaagtcaa atttatgcaa aaatgtgaga agccattttc
      241 acaaaatatt tcttaatact tgaaactaag cggctttttc acgacctctc aataaacggt
      301 gttcaaaagt cagtttctcg gtattaagtc aaatttatgc aaaaatgtga gaagccattt
      361 ttcaaaatta ctttttattg ctcaaggctg aacgtctctt tcacaacctc ttttatcaat
      421 ctgctacttc ttctttctta gcgaaactcc aaatcagtcc gataacaaaa ccgataactg
      481 ctggtacgat ccaccccatc cccaatttga aaaacggcaa gtagctttcc gcaacatata
      541 aaagattttg aacaataggt gtttgtttga tagtttctgg gcaagcgttc aacccatcaa
      601 aaatcgaagc aatcaatgta aaataagtag tcattcgata aacagccgta cgctgcttaa
      661 acaaaggacc aactaacact agtaaaatca gtgtcattgc taatggatag atgaacatca
      721 aaacaggcaa cgaaaattga atgatattcg tcaagcctac gtttgccgct aaacaaggaa
      781 ggatactagc aagtgcaaca aagaatgcgt aatttctttg cggaaacaaa tctgtgaatg
      841 tttctgcaaa agctgtaatc aaaccaatac cggtcttcaa gcaagctaat ataacgataa
      901 atgctaataa gatactgcca taagtaccta aataatgatc agcaatctga gccagcgtga
      961 tcccgccatt ttcacttaga gcaaagctac ctaagctcat agcacctaaa taagcgagca
     1021 aagtataaat gattcccatc aatataatgc tgatcgcacc agatttgatc gtgtctttag
     1081 cgatttcagc aggttttgtt acacccatgt tttggattgt tgtgacaatg atgatcccaa
     1141 atgctaaagc agcaagcgca tctaatgtgt tatatccttg agtaaaccct gtgaaaaaag
     1201 catgctcttg ataatttggc tgaataggcg cttgatttac agaacctagt ggattcaaaa
     1261 aagcaaggag aagcaaagca cctaataaaa ccaaaaatgc aggattcagg aactttccaa
     1321 cataatctaa tatctttgtc ggttttcttg aaaaccacca agccagcaca aaaaatacaa
     1381 tactgaaaat tgctagatat agcgtctgtc tgctaggatc gataaatggt gctaaaccaa
     1441 tctcgaaaga tgtggttgca aggcgaggta aagcaaaaaa cggtccgata actaagtaaa
     1501 gcaagatggt aaaaaccatc gcatatgttt gatttatccg ttttgctaat tcatatacac
     1561 ctgagctttt cgatacacca atggcaatca cccctaagaa gggaagaccg ataccggtaa
     1621 ccaagaaacc tagattcgcc caaaaggtag cagcgcctgc ttcttgaccc aaatgaacgg
     1681 gaaagataag atttccagca ccaaaaaata gaccgaaaag catggagcct ataaaaagat
     1741 agtctttaa
//
LOCUS       DADVXK010000206         1731 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.214, whole genome shotgun sequence.
ACCESSION   DADVXK010000206 DADVXK010000000
VERSION     DADVXK010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.214"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            49..1572
                     /locus_tag="KB909_002869"
     CDS             49..1572
                     /locus_tag="KB909_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBB6838818.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          627 a          277 c          350 g          477 t
ORIGIN      
        1 atcaatcgta tgatcgatca aatggagtct gtcaaaaaag aaagttattt ggaccctact
       61 gtttttgaag cagaggaaca tatccaaaaa gtcattcata aaatgttccg tccagacaat
      121 gcctatacaa aatttgattt tcgaaatggc cgtccaacga agtctgcgat cttaaccacg
      181 agttccattg atatggccaa aaagtattat cgggccatca aagagatgac gaaagaatct
      241 gattggttaa taaaagagtt tcccaatcag cctatccgtg aaggacgaac gatggaggat
      301 cctgatttcc cacgaatcgc tattacctat tcattagaag aaaatagccg agattcaagt
      361 gcccaacaag aagaaatgca aaaaattatt gaggaatata atcagtatta tgatactgcc
      421 tggtcactag cagacattga gcgttataac ggagacatca ataatcgttt ggcacgaaaa
      481 agagcggaat tcaaacaatt tgggaaacaa atcgatttag taatcgtagt ggatcgtcta
      541 ttgacaggtt ttgacgcccc tacgattcaa accctatttg tggatcgtaa tctagagtat
      601 gcaggattga tccaagcctt ttcacgtacg aaccgtacgt atcctgaaaa aacaaaagga
      661 ctaattgtta ctttccgaaa gccagcgaca atggagaaga atgtcgagga tgcgacaaaa
      721 ctgtattcag aagctaaaga agaatcgggt ttgatttatc caagttacca agaatccaaa
      781 aaaagattca agcaagcata tggtaagtta aaagaggttt catccatgga atccattgat
      841 gaacatacgc cacttgaaat ccgtatcgag tacgtcaaag catttcaaga attgaatcgt
      901 gcgtatgaat cgttagtgac ttatgatgat tacaatgatg acatggtgca atcttcaact
      961 ttgaacaatc aaattcaact tttggaagaa caaattggcg tgtacgagac cgtgaagggt
     1021 tcattgatgg aggaagaacc agaaaaagag ggagaagatt tttcaacgat cgaattttat
     1081 agtgaaaata ccactaagtt gtatgatatt gattctactt atattgatca attactagga
     1141 acttatgctg cgaatagttc agatgcacga gaagaaattg aaaaagcttt ggctaaattg
     1201 aataaaacag aaggagtcaa agaagtttac cgacaaattt taaatgcatt tgatgtgggg
     1261 actttagata gtaatgaaga tatctttgtc attaaacgtc gctattttac acaagcaagt
     1321 gataatttga ttcatgcctt ttccaatgag tggtttgttt ctgagaaaga attacatgct
     1381 tctaatctgc aatatatgcc aggtgaagat ccaattccta atatgaaagc aattatcaac
     1441 agtaaggatt acgaaggata taaagccaaa catccagaag cgaaaccatt taaataccca
     1501 caagaaatga agcgagcatg gcgtaaaatg ttagatgatg agttgattcc acttgaaaat
     1561 gaattgaggt aaacgagaag agttaagaaa attgtacgat tcaaagatag tagtaaagtg
     1621 gaagtgtaga aaatagggat agatgtcttt ttacttgttc acattttata acggagtatt
     1681 taagaaagct attgaataat gattcttcca tctttttcat tcatttaccg g
//
LOCUS       DADVXK010000207         1723 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.215, whole genome shotgun sequence.
ACCESSION   DADVXK010000207 DADVXK010000000
VERSION     DADVXK010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.215"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            190..546
                     /locus_tag="KB909_002870"
     CDS             190..546
                     /locus_tag="KB909_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6838819.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            556..1455
                     /locus_tag="KB909_002871"
     CDS             556..1455
                     /locus_tag="KB909_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBB6838820.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT          577 a          296 c          350 g          500 t
ORIGIN      
        1 aggttgcttt ttgggtcttt ttccgttcaa gaaactgaac gaagaaaagg gaaagttgtc
       61 tcttttgtga taagagaaat cataataaac gaatgactta ctttccaata aattgagaac
      121 agtcagaacc agacaaatta gttgcatctg atgaataaag tgattattct atgacatgag
      181 gtgatacaga tgaaattaga agtgacaaaa gaagcacaag aagtattgaa gaataaatta
      241 gaagcagacg atcaactttt attagatatc gaaaacggtg acggtccatt tgcagaaagc
      301 caagtcagtt gccaattgga tacggcattt cgattgatca ttgtcaaaaa agatacacaa
      361 acagatctaa gtctttattc tgtagtggct gatacaccag ttggaccaat caaaatcaaa
      421 gacagtgcaa tactttacat ggatgatcca tccacacttg ctttagaacc aacttataat
      481 agtttacaat taaaaggacc aagcggcttg agaaaaggca acttgcaagt tgttcgaaaa
      541 gactagaggg ataaaatggg aaaattggcg atcatcagcg acctacatgt ggacatcaat
      601 aaattcggcg aatcagagct gatgcagctt tggcaagttt tgcaaaagca caagatcact
      661 cggcttcatc tagccggaga tacggctaat aaagtagacc gttgcctagc tgttgtcgaa
      721 tttttcgtca ataaaggatt atctacgaca tttcatttcg gcaatcacga gttggcagat
      781 gtgcccaatg aacagatgat ggaccatttt ccagacccac attttttaaa tgaacggtat
      841 attgctttaa atgagcagac cgttctttta gggatgaatg gctggtacga ctatcagttt
      901 tccgaattga aagattacga ggcaatcgta cgaatgaagc gtttgtattg gtatgatcgg
      961 ttcatccagc gtgggaaaac agatctcgag gtcaatgcag aaatgcttgc agctgcaaaa
     1021 aatttgctag accagctgga agcaaaaaaa cttgaggtga ttttatccac tcatttcgtt
     1081 cctaaacggg catttatcat gtatcaatct gctccttatg agcgttggaa caaattaaat
     1141 gcatttttag gatcagaatc attcggagaa ttacttgacc gttattcaaa tatcaaacaa
     1201 gtagtttttg gccatacgca tcgtcgcttt gaagataaat ccatcggtca cacgatttac
     1261 agctgcagac cttttggtta ttattatgaa tggcagctga cccgagattt tgtcttgaaa
     1321 gaacagttgc tagacagcta tgatcctatg aaattacgtg tcctcttgcg tgcccatcac
     1381 ccagcttttc aggcctatca aacacaacat ttgcaagagg aatttgaaca agcgatgaca
     1441 atcgttccgt attgagacag cattagtaat gtgtaaaaga aaataccttg taaaacataa
     1501 ggataagtaa gagcagtaga tccatttatc gtggatatgc tgcttttttt gcggaaaata
     1561 atcagcgaat gtttatttga tcggatgatt tgtaactcgc agagtactag atgcaagcgt
     1621 gtattctttt tttgaacgat aatcacaaaa aaaaatataa tatacatttt ttatttaatt
     1681 ataattaata ttgattgaag tctaggcagt caagtcacat ttt
//
LOCUS       DADVXK010000208         1718 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.216, whole genome shotgun sequence.
ACCESSION   DADVXK010000208 DADVXK010000000
VERSION     DADVXK010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.216"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1482
                     /locus_tag="KB909_002872"
     CDS             <1..1482
                     /locus_tag="KB909_002872"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBB6838821.1"
                     /translation="LSDRLLEQVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLI
                     ATIVDILGYAISPEYLFNVLADQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQ
                     SKKLGTDEQQRNVTITEVIKKLNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFY
                     TPHMVSDMMAQIVTLDQKERRFFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNT
                     TTYNLAKMNLILHGVDAEEMNLRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTT
                     FLDDSRFNRYGKLAPKSKADFAFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQK
                     LLEDGSIYAVIGMPANLFFGTSIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLS
                     EENIQKILETYAERKDVEKYAHLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGN
                     DIKKIRQEQQVLEKELLEAISSLQTTPENEAWLQGALEVFKHE"
     gene            1475..>1718
                     /locus_tag="KB909_002873"
     CDS             1475..>1718
                     /locus_tag="KB909_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6838822.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
BASE COUNT          596 a          287 c          365 g          470 t
ORIGIN      
        1 ttatccgacc gtttgttgga acaagtggtt cttttagcag atgaatcctt agaggaatat
       61 gatacggtaa gcaaacaaac gatgttgtat cgcgaattac tttcagatga agaatcaaaa
      121 gaagatctga ttgcaacaat cgttgatatt ttggggtatg cgatttcgcc agagtatctt
      181 ttcaacgtct tagcggatca agcaaaacaa gcaacgttcc aattgaatga tctaaacaaa
      241 gcctttgtgc aattggcatc tacctacaat caatttaatg ggttatttga tgatgtggat
      301 ctccaatcaa aaaaactagg aacagatgag caacaacgaa atgtgacgat taccgaagtc
      361 attaagaaat tgaatgacgt ggaagtttta ggtcacgatg gggacgtgat cggggatgct
      421 tatgaatttc tgatcagtca atttgcttca gaagcaggga agaaagccgg agaattttac
      481 acgcctcata tggtttctga tatgatggca caaatcgtga cgttggatca aaaagaacga
      541 cgattcttta gtgtttttga tccaaccatg ggttcaggtt cattgatgtt aaatgtgcgt
      601 aactacttaa ctcacccaga taacgttaaa tatcatgggc aagaattaaa tacaacgaca
      661 tacaatctag caaaaatgaa cttgatttta catggggtag atgccgaaga aatgaatctc
      721 cgcaatgggg atacgttgaa taaggattgg ccaacagatg aaccttacac atttgatgca
      781 gtagtaatga acccacctta ttcggctaat tggtcagcag atacgacctt cttagacgat
      841 tctcggttta atcgttatgg aaaattagcg ccaaaatcca aagcagattt tgcgtttctt
      901 cttcatggtt tctatcattt gaaggaaaca gggactatgg ccatcgtctt gccacacgga
      961 gttttattcc gtggcgctgc agaaggggtc attcgtcaaa aattactaga agacggcagt
     1021 atttatgctg tgatcggtat gcctgcgaac ttgttcttcg ggacatcgat tccaacgacg
     1081 gtgattgtat tgaaaaagaa ccgccaaact cgagacgtat tattcattga cgctagtcga
     1141 gaatttgtca aaggaaaaaa tcagaataaa ttatcggaag aaaacattca aaaaatcctc
     1201 gaaacctatg ctgaaagaaa agatgtcgag aaatacgctc atttggcaaa ctttgatgaa
     1261 atcaaagaaa atgactataa cttaaatatt ccacgctatg tagatacgtt tgaagaagaa
     1321 gaaccaattg atatggttca tgtcggaaat gacatcaaga agatacgaca agaacagcaa
     1381 gtgctagaaa aagaactttt agaagctatc tcttccctgc aaacaacacc tgaaaatgaa
     1441 gcgtggttac aaggtgcgct ggaggtgttc aaacatgagt aatgatatac aaccagaaat
     1501 tcgtttccca ggatttacgg aagcttggga acagcgtaag tttgaatgct tacttgataa
     1561 aaaagatgga gtaaggaggg gaccatttgg gagtgcctta aagaaagaat tctttgtatc
     1621 taatagcaat tttgttgtct atgaacaaca aaatgctatt tatgataatt acgaaacaag
     1681 atataaaatt actgaaaaaa aatataatga attaatca
//
LOCUS       DADVXK010000209         1664 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.217, whole genome shotgun sequence.
ACCESSION   DADVXK010000209 DADVXK010000000
VERSION     DADVXK010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.217"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            131..505
                     /locus_tag="KB909_002874"
     CDS             131..505
                     /locus_tag="KB909_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6838823.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="KB909_002875"
     CDS             complement(619..1248)
                     /locus_tag="KB909_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6838824.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="KB909_002876"
     tRNA            complement(1382..1454)
                     /locus_tag="KB909_002876"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DADVXK010000210         1626 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.218, whole genome shotgun sequence.
ACCESSION   DADVXK010000210 DADVXK010000000
VERSION     DADVXK010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.218"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(608..1222)
                     /locus_tag="KB909_002877"
     CDS             complement(608..1222)
                     /locus_tag="KB909_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6838825.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          524 a          299 c          254 g          549 t
ORIGIN      
        1 atttatatta agtattttat ttctctgttt ttccttaaaa ttcttttttt atttttagat
       61 tagagaaaat ctcgtcctgt ttttttcatt ttacaatcat tgaaaaattg aatttcattg
      121 caaaaaaaat aataaacact tataaatatc cattatctat ccttcaattt ttgtgtattt
      181 tatttctatt agaaaaaggt atcctgttgg acaattttgt tatatcaggt aaacttcatt
      241 gcaataatga taacaaatgt actataatta ctttgtaaag agttttgggg aagactcttt
      301 catcaacgtg tattaagaga caagaaagaa tccatatgga ttctttcttg tctctttttc
      361 cactactttt tatttttctg acactacata ttcttataac tcatttctca taactgtgaa
      421 acaacttata aaaataacaa actttaaaca aaacaagctt aaaatcaaag atgatccatc
      481 ttaaaataac taaaacaaaa aaagtagtcg ttgttaatcc tcattaataa tcgttttctt
      541 tttttcaaac gctccatttt tatgtggaac attatttttt taaggaactt tgtcaacatg
      601 tggataacta ttttccactt gtgtcctgga ctagctgttt tgctgtaaaa tacaaaactt
      661 gctgcagcaa aaagatcgtt gcaagagagg ctgttccgca gatcgctgga tctagatttg
      721 gcaaagtcaa gactgcatca tgtaaattgg cgtggttgtc caaaaccaaa tcagcaaatt
      781 caaataatcg caaaccactg ctatgttgcg atttgatact tcgtgacaaa tcaaatccag
      841 taacaatgat taatggatga ccattttctt tgatccactg agctagttcg atgattgccg
      901 ggtttcttcc ttcattcgaa agaagaagaa aaatgtcttc tgatttgaca gaaagctgat
      961 caataattgc ctgtcctgca ccttctagcg tttcatagac acctccggct ggattttcaa
     1021 tcaatatact tggtacaaga tccggggttt gatcccaaaa ttcaaatgct acaccactta
     1081 gtgtgcggct agcatatatc tgcaatctac caccttgatt aatttgtttc gcgatccaag
     1141 tgccagcttg aagcatcagc ggctcttcta tccttaattt ctcttccaat tggtgataat
     1201 agtcaaaata acataaactc atttatctct cccgcctagc tatacttgac atgaatagaa
     1261 acagctgcct aatctaagga agtacataaa aaaacagtag ttagacagta acacatgtgg
     1321 tctttgctgt ttcaaacaca aaaaaggcat tgaacgaata cgcccaatac cttgacatag
     1381 caaataaaac aacgtgcaga ccatggaaaa tatctacata ggggtagaat tttcacccta
     1441 gattaggtac aataaattag gtcgatgcac tgcattgact atggcaaaat gatcggtcag
     1501 ggtgtatgtg tgtgactggt cattccctga ttcttagcgc caactaaggg tcagggagcc
     1561 tttttttatt cagctgtttc tatctgaatt tattgtaagt aatctcttat ccaagtgcaa
     1621 gcaaga
//
LOCUS       DADVXK010000211         1586 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.219, whole genome shotgun sequence.
ACCESSION   DADVXK010000211 DADVXK010000000
VERSION     DADVXK010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.219"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(21..1400)
                     /locus_tag="KB909_002878"
     CDS             complement(21..1400)
                     /locus_tag="KB909_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008270028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838826.1"
                     /translation="MMGNLVLSYNIYYFFITFLTMVVSYFSMKQIKNNRYISLLFSII
                     YTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQKWYWLSIGMTLVVYTH
                     LLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLSAGFLIPFIQQSRAQE
                     LKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAFIFIKKLTADDLFIFF
                     LGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYTMSIVIYYIFSTKNNS
                     WKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPEDAVAIAENYNHTDYANKESIYHP
                     DMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTPIYRYKGQVASINGKL
                     VQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTLILFLLYRFTFSKQKQ
                     PRREVQHSH"
BASE COUNT          611 a          223 c          255 g          497 t
ORIGIN      
        1 agtctttctt aaataaaaat ctagtgagaa tgttgtactt ctcttctcgg ttgtttttgt
       61 ttagaaaaag taaatcgata aagtaaaaat aaaatcaaag taacgataga taaatatctt
      121 gaagcaattg ctagttttgt gtactgataa gtaataacga ctttatttat acctggagga
      181 atagttaatt cagttgtgcc aaacttagat aattttgttt gtactagttt gccattaata
      241 gaagccactt gccctttata acgataaata ggtgtcgtca agacagtatt tttattattc
      301 gaattatcta attcaattgt aagtttgtta ctcataaaat gagttgttgg atttatttcc
      361 tggttaccta gtaaatattg atcattatta atcatatcag gatgatagat tgactctttg
      421 tttgcataat cagtatgatt gtaattttca gctatagcaa cagcgtcttc aggtgctata
      481 agtgttaatg aatctttgtt agcatggata gaattgctta ctcctgagag atgcaatatt
      541 agtgcaagaa acgtaaagac cattattttc catgaattat ttttagtaga aaaaatataa
      601 tagatcacta tactcatcgt ataggctata aataaagaag aaaaaccatt taaccgccag
      661 acaaattgta gactcttaac tggtgtatgg ttaaaaagtt gccaaggaaa taaattggtt
      721 gaacaaaaaa gaacaaatac accaagaaag aaaataaata aatcatcagc agttaatttt
      781 tttataaaaa taaaagcacc aatcaatccg agaaataaga ataatccaat agtatagttg
      841 ttatagttat tatttaaaat atgtgtcagc atatcactag gagccatacc acttaattct
      901 tttcccagtg ggactttcaa ttcttgtgct ctagattgtt gaataaaagg aattaagaat
      961 cccgcactta aaaaaaaggt gaggacggta gcttttaaaa gacttaagag tctagcgatt
     1021 ttttggtccc aaaaataaaa agaaagaaac aacgttcctc caataaatac agaaaccata
     1081 gcgacagaaa gtaaatgagt atacactact agcgtcatgc caatagacaa ccagtaccat
     1141 ttttggtaat ctctaatata aatttcgtaa caccccatta gtatcaaagg caaaaatgtt
     1201 aaagcgacag cttctcccaa tgaagcacga tggaatatgt caatggcacg ataggcggaa
     1261 aatgtataaa taatcgaaaa taacagcgaa atataacgat tgttttttat ttgtttcata
     1321 gaaaaataag aaacgaccat tgttaaaaaa gtgataaaaa aatagtagat attataactt
     1381 aaaacaagat ttcccatcat tttataaaat aaaaaagctg gataaagagt aagccatgga
     1441 taaaaaatat tcatcattgt tccatgatga tcgaagttat tgaagtttac tggagaactc
     1501 catacattat ctagtcctat gattcgagat aaatgaaagt aagtatcctg attgacacta
     1561 tgatagattc ccttagacat gaatag
//
LOCUS       DADVXK010000212         1508 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.220, whole genome shotgun sequence.
ACCESSION   DADVXK010000212 DADVXK010000000
VERSION     DADVXK010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.220"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..626)
                     /locus_tag="KB909_002879"
     CDS             complement(<1..626)
                     /locus_tag="KB909_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838827.1"
                     /translation="MDNHTRKLLVLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
     gene            914..>1508
                     /locus_tag="KB909_002880"
     CDS             914..>1508
                     /locus_tag="KB909_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6838828.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT          530 a          216 c          286 g          476 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gatgggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcta tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtctgccca
      361 caatcatagc atagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaatatct gagtacgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatacg
      601 agtaattttc tagtatgatt atccatagag cgactccttt ggtagggtga tgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caacaacaca aaatattata gaacccttta ttctaaagga
      781 tttcaaggtg tctgtttgca tttattagaa aaaagaaaaa gtattggcaa cagaaggtgt
      841 caccaacact agatattata gagccataat atgctgtata atatctagtg tataggctta
      901 agtggaggta tatatgaaaa tattaactgt tgaagatgat aatatgataa gagagggaat
      961 aagtgaatat ctttcagaat ttggatatac tgttattcaa gctaaagatg gaagagaagc
     1021 cttgtcaaaa tttaatagcg atataaattt ggttatctta gacattcaga taccttttat
     1081 aaatggttta gaagtgttga aagaaattag aaagaaaagc aatttaccaa ttctaatctt
     1141 gactgcattt agtgatgaag aatataaaat tgatgcattt actaatttag tagacggata
     1201 tgtagaaaag ccattttcat tgccggtctt aaaagctaga atagattctt taattaagaa
     1261 gaattatgga catttagaga agtttgaata taaggatcta tcggttaatt ttaatagcta
     1321 tacagctaaa ataaatggtg aagaaataga tgtaaatgca aaagaactag aagtattaaa
     1381 atgtttattg gataataatg gacaagtgtt aacaagaatg caaattattg attatgtatg
     1441 gaaagatagc gaagaaactc cttatgatcg agtaatagat gtatatataa aagaacttag
     1501 aaaaaaat
//
LOCUS       DADVXK010000213         1493 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.221, whole genome shotgun sequence.
ACCESSION   DADVXK010000213 DADVXK010000000
VERSION     DADVXK010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.221"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(181..480)
                     /locus_tag="KB909_002881"
     CDS             complement(181..480)
                     /locus_tag="KB909_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6838829.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            831..1463
                     /locus_tag="KB909_002882"
     CDS             831..1463
                     /locus_tag="KB909_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6838830.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT          511 a          230 c          209 g          543 t
ORIGIN      
        1 ttaacattat tagtttatac tagctgtttt tgtgttaatt aaaggataaa atacaatata
       61 aagaaacatc tgtttcttta tttagaataa aaaaatacag actctgttca aataaatgaa
      121 cctagcctgc attatgagat tgactatact ttttaattca ttgagatgaa taactcgttt
      181 ttataaatgc ccaaaagtaa tcggtgccga agccattcct cgacctaatt ctttttcaaa
      241 ttttcctatt gttgatatct ccatataaaa cggtgatact ggtttagaca attctcccct
      301 gattgctaac ggacgtaaac tacgttccaa attatttatg actttaggat aatactgacc
      361 tttttctaag cctgtctttg cgtctatcaa aagtatacgt tccttttctt tgatctctgg
      421 atttaaaacg agatcatata attttagtac catgttttct atttcttcac ttttagacat
      481 cacgatttcc tcccaaaaat atatttcttc ccactacatt ctataaacaa agtatacgct
      541 acatctagat ttttttaaat cattactgga ttgttaaaac ctttcaatac actgttatgg
      601 caacgatttt tattttaaaa acattctaaa ttaaatcagt aaaaattttt attctaagat
      661 ttttattaga attacgccta atttgtgtct ctcagggcaa ttctaagaac gtttcaagag
      721 atagcgacac tatcgttatc gaaaaaggcg aaaacctatc tcattttctg ctaatgtaag
      781 ttggtttagc ttttgttaat atgactttat gaaaatggag gtaattaaat atgatttttc
      841 ctaaagttaa tgaagcaagc ttgaataaag gatccttttt tcatatctat gaaaacgaag
      901 attttgaact gtataatatc ctttcacaaa aagaggtcat cgaaaaccaa ataatctgcc
      961 atccaattat ttacaaatct attttcaagt atgcattttt tgcttccaat gattttcaaa
     1021 gaatggagat taccgactgt atattcgaaa actgtgattt ttcaggctgt atattgacaa
     1081 aaagcatgtt gcatcgcgtg aaatttgtca attgtaaatt aacaggtact aaattgatgg
     1141 aaagttatat tgggaacacg ttattcgaga attgtaaaat ggactatgta aatttatctg
     1201 gttcaaacat aaaagaaagt acctttgagc actctgtctt atcaagcgca gattttgtag
     1261 actgttccct cactaaaata atgttttcta ctaatgattt agaaaatgct agcttttttg
     1321 atactgattt aaaaaatatc gatttaagta gcaactcctt tgaaatgatt gaagtacgct
     1381 cggaacatct aaaaaattgt acgcttaatc agttgcaagc acttggtttt gctagaaaat
     1441 ttttacaaat aaaagtagta taatcaaaat gaatatataa gataaatttt tag
//
LOCUS       DADVXK010000214         1404 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.223, whole genome shotgun sequence.
ACCESSION   DADVXK010000214 DADVXK010000000
VERSION     DADVXK010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.223"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            24..1013
                     /locus_tag="KB909_002883"
     CDS             24..1013
                     /locus_tag="KB909_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6838831.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            995..>1404
                     /locus_tag="KB909_002884"
     CDS             995..>1404
                     /locus_tag="KB909_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6838832.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLN"
BASE COUNT          499 a          187 c          267 g          451 t
ORIGIN      
        1 atgactttat aatacttatt agagtgaggg ataaagaaat gagacaacta cacaaagaac
       61 agattgaaac agcaatggca gcgttaaagg aaaagacaat tgatcatgta tattttacag
      121 catgtggggg ttcacaagcc gttttaatgg ctggtcaata tctatttgat aaagaattaa
      181 ctgtaccttg tcatgtttat actgctaacg aatttaacta tgctatacca aaaggattat
      241 ctgaaaattc tttagttatc acttgttccc attctggcac aacaccagaa actgtagaag
      301 caacaaaaaa agcaagagaa tttggagcaa tgactatttg tttatctaat gaagaaggat
      361 ctcctctatg ggaagcagct gaatatcctg ttcactatga ttggggtaaa gatgttgatg
      421 ctagtgattt aaataaagga attctttatg gtttattatt taatatttta cttgttttag
      481 atggctctaa aaaatgggaa acttgcttga atgaatttga taagttaaat gatcttgtta
      541 ttgctgaaaa gagcaaattt gaaataactg ctaaagaatg gggtaaaaac caaaaacgag
      601 ataaaattat ttacacaatt ggtagcggta tcaattacgg agaaatttac tccacagcag
      661 cttgctggtt catggaaatg caatggatta attctaatgc tattcattct ggggaatttt
      721 tccatggtcc ttttgaaatc actgattatg atgtaccatt catcttagtg aaaagtattg
      781 gagatacaag atttttagat caacgggtag aagacttcac taaaaaattc agtaataaat
      841 taatggtttt agaccaagct gattttgact tagaatctat agatagtgta gcgaaagaat
      901 atattgcagc tgtacttagt ggcgttgtta ttcgccaaat ggtagaagcg attgcttttg
      961 aaagaggcca ttccttagat gttagacgct atatgtggca aatgaaatat taattaatag
     1021 gaggttgcaa aagatggcaa atcaattatt tcacattgtg attacaacac attctaccct
     1081 ttgtgagggt tatttaaagg caacaaaatt aattttaatg aatgacgcca caggtattag
     1141 tgctgttcca tttaaagaaa atactagtcc agatgatttt gaggagagta tgaaagaaat
     1201 aattagtcag catcatttgc aacctctaat tattttaacg gatttaattg gaggaacacc
     1261 taataatgtt tctattaaac agttgaacaa caatagaatt caaattattg ctgggattaa
     1321 tttacctctt ttactggagt tattaatggc ccagtcagct ggtaaatcta tagaagaaat
     1381 agattttaag gaattactga ataa
//
LOCUS       DADVXK010000215         1370 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.224, whole genome shotgun sequence.
ACCESSION   DADVXK010000215 DADVXK010000000
VERSION     DADVXK010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.224"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            151..1023
                     /locus_tag="KB909_002885"
     CDS             151..1023
                     /locus_tag="KB909_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6838833.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          435 a          235 c          312 g          388 t
ORIGIN      
        1 aaattattag aattttaaaa aatgataaaa attcaaaaag aaaaaatagt agttatttac
       61 ttgtcatgtt actaaataaa aaaataattt aaatatgata tatagtcatt tatttagtga
      121 tttcattcta aaataaaggg agaaatgtct atgctatacg gtgcaattga agcaggcggc
      181 acaaaatttg tgtgtgccat tggcgatgaa gaaatgacga tcaaggaaag agtgagcttt
      241 ccgacaacga cacctgagga aacaatgcct ttagtcattg acttcttcaa acaataccaa
      301 gcagatttag cagggattgg gattggctca tttgggccta tcgatatcca tcgcgattcc
      361 gccacttatg ggtacattac ctcgaccccg aaattggcat ggcaaaattt tgatttcatc
      421 ggtaccatga aaaaagaatt tccgatcccg atttcttgga caacagatgt caatgcggct
      481 gcctatggtg agtatgtctt cggcagtggc aaaggattga gcagtgtcgt ttactatacg
      541 atcggtacgg gtgttggcgg cggtgcctta caagaagggc gctttatcga agggtttagt
      601 catccagaaa tggggcatat gctcgtcgtc cctcatccaa aagatgactt tgctggcagc
      661 tgtccatttc atggcaactg tttagaaggg atggccgctg gacccgccat cgaaaaccgc
      721 ttagggaaaa aaggacaaga ggttgcagaa gatgatcctt attgggaaat cgaagcctcc
      781 tatattgctc aatgtgccta caatacaacc ttgatgtttt ctccagatgt gatcattttt
      841 ggcggtggtg tgatgaaaca acgccatatg ctgcaaaacg tccacgacgc atttgcaaaa
      901 ttggtcaatg ggtatgtcga aacacctgag ttaagcaaat atatcgtgac cccagcatta
      961 gaagacaacg ctggaacgct cggttgtttg gcattggctc gagaagcggt cttacattca
     1021 taaacgaaaa aaggctcttc gacatttagt gttggtagag aaagatacaa ctgaaaattt
     1081 agtcataacc agttaggcag agtgcttaac tggtttttgt tttacttgga agatcaagcc
     1141 ttgaatgaga taaattcttg ctcgaaagtt atggaaattt cgatagccgt aggccacttg
     1201 tattgtgcaa tagtttttta caaaaaaaag ggggtgcgga tatttttttg gaccttttta
     1261 acaaataggt tctgttgcaa agttttaaat ctactatcag ataaggtaga ataatagaaa
     1321 aagatagcag gaggaatgac gatgagtcat tttaaaggaa agcaatttca
//
LOCUS       DADVXK010000216         1362 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.225, whole genome shotgun sequence.
ACCESSION   DADVXK010000216 DADVXK010000000
VERSION     DADVXK010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.225"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            80..>1362
                     /locus_tag="KB909_002886"
     CDS             80..>1362
                     /locus_tag="KB909_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBB6838834.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          464 a          262 c          257 g          379 t
ORIGIN      
        1 tttaggtatt aaaaaacata tcgttctcta gtatgattaa atcaccacaa aataaacaac
       61 tgagaggacg atacgctata tgaatgattc tatcaaaaaa atgctgagaa taacagagaa
      121 agatttgatg attacagagg tctcttacga gacccttcag aagaaaaaga cgttggtcgt
      181 cgatgctgtt ctctcgccta ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga
      241 tggaaacggg aaagcaatta tagtgaaaaa tggaaaaaag gaaacgattg tccgttttga
      301 acaatacaat catatgcctt tggttatgcg cctaaaaaag caacgctata cctgtaaaaa
      361 ctgtcgcacc cattggacgg ctcaaagtta ttttgtccaa cccagacatt caatcgcaaa
      421 tcatgttaga tataaaattg cttctttact gactgaaaaa gtatctttat cttttattgc
      481 gaaaagctgt caggtatctt tgaccaccgt tattcgtaca ttgaaagagt ttaaaagcta
      541 tttaccaaag caatctaaga agatcctccc cagagtattg atggttgacg aatttcgttc
      601 gcatgcttcc atagaagata agatgagctt tatttgcgcg gatggcgaaa caggaaaatt
      661 aatagatgtt ttgcctacgc gtaaattacc tcgattaaca agctatttct taggttgtac
      721 caatccagaa gaagtagaat tcttggtgac agacatgaac gccgcctact tccagctcac
      781 caaacgtgtt ctgccaaatg cgaaagtcgt gattgatcgg tttcatattg tcaaacacat
      841 gaatcaagcg ttcaatgagt tgcgtatccg tgaaatgaat gaacttcgta aagccggaca
      901 gaaaagccag gcagaaaaac tgaaaaagaa ctggcgcttt ttgctaaaaa atcgtgcaaa
      961 catcaaccat tatgaataca aaacatggaa aagtttccga gcaccaaaat acccatttct
     1021 tactgaagca atgatgattg atcgattgct tgagttttct ccgcccctaa aggaggcgta
     1081 tccctttttt catgaattag ttgaagcctt tcgagacaaa gaccctgact tatttttctc
     1141 cttattggca gaacttcccg aaacgttaga tgacagcttt cgggaaaagc ttcaaaacct
     1201 tctgacctat gaagaaggca tcaccaacgc aatgatctat ccttattcca atggaaaaat
     1261 agaagcgaag aatacccaca taaagacaat gaaacgagta tcctacggat ttaaatcatt
     1321 tgagaacatg agaattagaa tctttttgat caatcaatta at
//
LOCUS       DADVXK010000217         1360 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.226, whole genome shotgun sequence.
ACCESSION   DADVXK010000217 DADVXK010000000
VERSION     DADVXK010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.226"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..712
                     /locus_tag="KB909_002887"
     CDS             <1..712
                     /locus_tag="KB909_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HBB6838835.1"
                     /translation="TPFDEESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLL
                     STGMADIHEVSEAVDCFIDSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSD
                     HSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLG
                     DGVKRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGK
                     KVKRPISADSVLLEEDVE"
     gene            709..>1360
                     /gene="neuC"
                     /locus_tag="KB909_002888"
     CDS             709..>1360
                     /gene="neuC"
                     /locus_tag="KB909_002888"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBB6838836.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELEN"
BASE COUNT          467 a          178 c          284 g          431 t
ORIGIN      
        1 tactcctttt gatgaagaaa gtgcagactt tctaaaacaa attggtgtac aaggatttaa
       61 aattggctca ggagatttaa caaatttacc ttttcttaga aaaatagata tgtatgggtt
      121 gccagtttta ttatctacag gtatggctga tattcatgag gtcagtgagg ctgtagattg
      181 tttcatagat agtccagtta ctattttaca ttgtacttca aattatccgg ctagttctga
      241 agatattaat ttattggcga ttaacacatt aaaagaaatg ttcgggatac ccgttgggta
      301 ctccgatcat tcattgggat atgatgttgg tatttgtgct gttgcgatgg gtgctaaggt
      361 aattgagaaa cattttacct tggataagga actacctggt ccagatcata aagcttcttt
      421 agatcctcag gaatttgcag attttgtaaa gcatattaga aacactgaaa tatttttagg
      481 tgatggtgtt aagcgagcaa tgccttctga acttagtaca aaagaagtat caagaaaaag
      541 cctagtggtc actgagaatt taaatgtggg agatattctt acagagaaat ctcttacaat
      601 aaaacgtcct ggaaatggaa tagctcctaa gtttttatat caatatattg gcaaaaaagt
      661 taaaagacca ataagtgcag atagtgttct gcttgaggaa gatgttgaat gaaaaaaata
      721 cttatagtaa gtggaacacg agctgattat ggaatatata aacctgttgc tgagaattta
      781 ctacaagata attgggatgt atcatttgtt gtttctggaa tgcatttatc ccataaatat
      841 ggatttacta aagaattgat cttagctgac ggatttagaa ttagtggaga agttcaaagt
      901 ttgtttttag agaacaataa gggaaacatg gctcggtctg tggcattaga gataaatggt
      961 ttcacaaata tatttgaaca aactagccct gattttgtat tattactagg ggatagagga
     1021 gaaatgttgg cagctgcgat agcttgtttg tatcttggaa tcaaaacagc acatattcac
     1081 ggaggcgaag tgtctggtac tgtagatgaa tcaataagac atgccataac gaaaatagca
     1141 tctgttcatt ttgctgctac ggaaaaaagc aaagagcgtt taataaaaat gggggaagat
     1201 tcttggagag tttttcccgt cggagctcct agaatagata ctattttaaa taatagatta
     1261 cctagtttta gagatataaa agaaaaatat catctaaaat ttgaaaagaa aaaatacgtt
     1321 ttgcaagtat ttcatccagt tgtaaccgaa ctagaaaata
//
LOCUS       DADVXK010000218         1355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.227, whole genome shotgun sequence.
ACCESSION   DADVXK010000218 DADVXK010000000
VERSION     DADVXK010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.227"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1355
                     /locus_tag="KB909_002889"
     rRNA            <1..1355
                     /locus_tag="KB909_002889"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DADVXK010000219         1355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.228, whole genome shotgun sequence.
ACCESSION   DADVXK010000219 DADVXK010000000
VERSION     DADVXK010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.228"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            97..1104
                     /locus_tag="KB909_002890"
     CDS             97..1104
                     /locus_tag="KB909_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6838837.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1116..>1355
                     /locus_tag="KB909_002891"
     CDS             1116..>1355
                     /locus_tag="KB909_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HBB6838838.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQS"
BASE COUNT          534 a          169 c          251 g          401 t
ORIGIN      
        1 gttttgacat cattattgat aattagttta gttatatatt ttttaaagat taagaatcga
       61 attatagatg actataattc ataggaggag atataagtgt ttaaaggaaa aacaatatta
      121 gtaactggcg gaactggttc cattggaagt gaaattgttc gtcagctttt aaaatatgaa
      181 ccaaaagcta tcagaattta tagtagaggt gaagaaaaac aattttatat gcaacaagag
      241 ctctcaaatc acactaattt gagattttta attggtgata tcagagactc tcaaaggatt
      301 gattatgcat gtcgtgatgt ggatattatt tttcatgctg ccgcaatgaa acacgttcca
      361 gcaagtgaat ataatcctat ggaagctgta aaaacaaatg tgatgggaac tcaaaatgta
      421 atagatgcag cgatcaaaaa taatgtaaaa cattttgtag gtatcagtac agataaagta
      481 gtgagtccta ctaacaccat gggtgcgaca aagttattga gtgaaaaatt aataatagct
      541 gccaatcagt ataaaggaaa aacagaaaca atattttctt gtgtaaggtt tggaaatgtc
      601 atggggtcaa gtggatctgt tattcctctt tttagtaaac aaataaaaaa caataaagat
      661 attactttga cagatgttga tatgacacga tttatgatgt caataccgga tgctgcaaga
      721 ttagttctgt ctgctgctat gaattcaaaa tttggagaaa catatgtctt aaaaatgccg
      781 gcaatcaata ttttaacttt agctcaatca ttaataaaaa tatataatga tacacatgat
      841 gaaaaatata gaggtgaaat aaaagttgta ggtatcaggc caggagaaaa attatatgaa
      901 gagctaatga ctacagacga aattgaacgc tcatatgaaa atgataaaat gtatatcatt
      961 ccaccacact atcatgctac tgacgaactg tacaaagatt atgaaaaaat taaaatcact
     1021 gcatactctt cagatgcaac agaattaatg agtggacagg aatttattag aatcgcaaaa
     1081 gagaataatg tcgtgacttg gtaaggagtt ttatgatgaa atcagaagta tatgtaattg
     1141 cagaaattgg tgtaaaccat aatggaagtc tagatttagc tttagaaagt attgataaag
     1201 ctaaagaatg tggagctaac gcggttaaat ttcaaacatt taaaacgaat aagctagttt
     1261 ccaaaaaggc tccaatggca aaatatcaga aggataatct taaagaggac agttctcaat
     1321 ttgaaatgct aaaaaaatta gaattatctc aatct
//
LOCUS       DADVXK010000220         1352 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.229, whole genome shotgun sequence.
ACCESSION   DADVXK010000220 DADVXK010000000
VERSION     DADVXK010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.229"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(70..1167)
                     /locus_tag="KB909_002892"
                     /pseudo
     CDS             complement(70..1167)
                     /locus_tag="KB909_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT          408 a          279 c          234 g          431 t
ORIGIN      
        1 tttcataaat ctattataaa agaaaagact gtagacatca tccataaaat ggactttgtc
       61 tacagtctgc gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga
      121 gtgaatactt tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc
      181 aaagagttgt tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg
      241 agaccaccga ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact
      301 gtagaatttt ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa
      361 cgcatttcga acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt
      421 tgcgccttct ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc
      481 acgtactttc agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag
      541 ccataggcct aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc
      601 atattcttta gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa
      661 tgcataacac ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc
      721 cgtgatatca gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc
      781 ggcgatatcg cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc
      841 ggagacatct cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct
      901 gggaacatca atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt
      961 tcgtcgattg tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt
     1021 caattctcct tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg
     1081 catatcctct acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc
     1141 atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa
     1201 ataaaaaccg tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta
     1261 cactctcatt tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc
     1321 ttttggattc cttcttaata tattgaatga ag
//
LOCUS       DADVXK010000221         1337 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.230, whole genome shotgun sequence.
ACCESSION   DADVXK010000221 DADVXK010000000
VERSION     DADVXK010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.230"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            291..833
                     /locus_tag="KB909_002893"
     CDS             291..833
                     /locus_tag="KB909_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838839.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            989..>1337
                     /locus_tag="KB909_002894"
     CDS             989..>1337
                     /locus_tag="KB909_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBB6838840.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          534 a          159 c          253 g          391 t
ORIGIN      
        1 gttgacgtct tggcatgaaa aatcctccag tgtgtttttt attattctac acaccttatt
       61 ttttctgtct agtctagtgt agccgattca aattgatgaa gcagatccca aagggctgct
      121 tcatcaattt tttcgtaagt gtccgtacac ttactgtgct tgctcatata ttaatcgatc
      181 atatactaat cgtgtaagaa caactttaag cataatactt atattgttat accatagttt
      241 ggaaaaataa aaaattatat ttcatcaacg tttcataaaa ggtgtgtaga atgttattga
      301 aagtagctat aaaatgctat tgtgtaaaaa ataaaggagg aataatttat gaaaaaatag
      361 taccaagagg agcatgccta ttacttgcat tatgtttgag cttaagcgca gttgggtgtc
      421 aaaaaagtaa tgaaaacaat aaaataaaag aaggacaatc cataagttct gaagaggaag
      481 gcatgtcaat taatgcaaat ggcaaaaatg aaacttttaa gccatcagat tatacattgg
      541 aggcaaagaa agaatatgtt tatgaatatt tagggcttaa atttaaactc tcagacaaat
      601 ttagaaatta tatagctgat aaaaagatag cgatgttaga tgatcaaagt cctatagata
      661 aagaactaaa gtatgctatt ttgacatttg agaaaatgac agaagaacaa aagaatgcag
      721 ttatagaaaa gatgggcgat ggatataaaa attggcaaaa tgagcttgaa agaattggga
      781 ctattggtat atttgaaaaa aatacatcag aagaaaaaaa tctaaaatta taaaatgtga
      841 tactcatact aaaataggag tttcaagtga tggaaaatac gattgctatt taagcacaaa
      901 tagcggagct gaaagtaatc ttctggatga attaaaaaga actgagattc aaattataga
      961 taaaaaagaa cgtcctaaaa atggttttgt gctatcagaa aaaactgatt tagaaaatac
     1021 agaagcattt aacaaagaat cggttaaaga tttacgtaaa ctaccaacaa aggacataaa
     1081 tggcaaggat tttacaagta aagattttga gaagtatgat cttactatgg taaatgtatt
     1141 tgcaacttgg tgtacagctt gtgtaaagga aattcctgat ttggttgagg ttcagaatga
     1201 aatgaaaagc aagggtgtaa atatcgttgg agttgttaca gatcctgttg atgataacgg
     1261 tgaaaacaag gaagcaattg aaaagtcaaa gttaatacat gaaaagacaa aggcttcata
     1321 tcctttctta atgccag
//
LOCUS       DADVXK010000222         1313 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.231, whole genome shotgun sequence.
ACCESSION   DADVXK010000222 DADVXK010000000
VERSION     DADVXK010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.231"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            23..1291
                     /locus_tag="KB909_002895"
     CDS             23..1291
                     /locus_tag="KB909_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBB6838841.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT          324 a          236 c          318 g          435 t
ORIGIN      
        1 ttttattgag gaggaatttt ttatggaaaa acaattaccg agtccagtac gcattttagt
       61 gtacatgctg aagtggctgg tgatcacagc gattctcggt atattcatgg ggagcttatc
      121 tgcttttttc ttaaatagcc tgacagttgt gacagatatc cgactatcac atccttggct
      181 cctttatcta ctaccagtta gtggtgcgct ttttgcttat ctctatgcgt atcacggcgg
      241 tctttctagt cgtggaaaca acttagtgat cgatcaagga aatggtggag aagaaaaaat
      301 cccgttgcga cttattccac ttacactgtt tggaaccata actacccatt tatttggagg
      361 atctgttggc cgtgaaggaa cagcagtcca aatgggggga gcgttagcag ataatacagc
      421 acgtttgttc cgattggata aatcagaacg ggaaatcttg attatcagtg gaatcagtgc
      481 gggttttagt tctgtatttg gcacaccttt agctggaaca ttatttggat tagaagtgtt
      541 ggcaatcggg aaagtccgaa cagaagcgat cttccctagc ttctttgctg cactgtttgc
      601 aaattttatg acagaaagct atggtgtttc tcatctacat taccaaatgg gtgtgattcc
      661 tgaatggagt atgttgctgt tcttcaaagt ttttgttgct gggattgctt ttggtttgat
      721 tggttgggta ttcagccgtt cgatcgtctt tttaaaagcg cgatatgcac aatggattcc
      781 tcatcctgtt tggcgaaata cgataggtgg ggctgtagtt gtagccgcag cattgatttt
      841 gcaaacacaa cgttatctcg gattgagtct tccattactg caggaatcat ttaatggaca
      901 ggcacatgtc tatgatttta ttgggaagtt attcttcaca gttttgtctt taggcgcggg
      961 atatcaaggg ggagaagtga caccattgtt tgaaattggt gcaacgcttg gtgcagcact
     1021 agcgcctttg ctccatgttt ctgttccttt tcttgcagga ttgggcttta tcggagtatt
     1081 ttctggtgcg acaaatacac cgattgcctg ctttgtgatg gggatcgaat tgttcggttc
     1141 acaagcggca gtatacttct ttatgatctg cttgatcagc tttatgtgtt caggcaacag
     1201 cggtatttat tctgctcagc aagtagcggt cagaaaaggg atactctttt tgccaatagt
     1261 taagagaatg aaagaaaaaa acaaggtgtg acatatgttt tgtcacacct tgt
//
LOCUS       DADVXK010000223         1311 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.232, whole genome shotgun sequence.
ACCESSION   DADVXK010000223 DADVXK010000000
VERSION     DADVXK010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.232"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            102..>1311
                     /locus_tag="KB909_002896"
     CDS             102..>1311
                     /locus_tag="KB909_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6838842.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          412 a          258 c          252 g          389 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta a
//
LOCUS       DADVXK010000224         1300 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.233, whole genome shotgun sequence.
ACCESSION   DADVXK010000224 DADVXK010000000
VERSION     DADVXK010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.233"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            17..1255
                     /locus_tag="KB909_002897"
     CDS             17..1255
                     /locus_tag="KB909_002897"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838843.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
BASE COUNT          387 a          186 c          225 g          502 t
ORIGIN      
        1 aaaaaggaga gattttatgc aagcagaaaa aaaacttttt aatcgtgatt ttatacttgt
       61 tgttatagga cagataattt ctttatttgg aaacgctatc ctacgatttg cattaccgta
      121 ctatttgtta aaagaaactg gttcatcagc tttgtttggt attgctacag cctgctcttt
      181 tttacctatg gttattttgt cgctggtagg tggtattatt gctgacagga caaataaaag
      241 aaacattatg gtcatactag attttgtaac agcaatcata attttagtat tttatttgtc
      301 attgggaaaa attcctatca tacctttgtt tattgttgct ttgatgttac tttatggtat
      361 ttctggtgca tatcaaccag cggtacaagc aagtattcct ctattggtat catcagataa
      421 acttaccgtc ggtaatgcta taataaatca agtaaatact ttagcaaact ttatcggacc
      481 agctataagc ggagtagttt ttcaatttta tggtatcaat cccattttaa ttgttagtat
      541 tatatgtttt actttttcag ccattatgga aatttttatc catattccac accaaaaaag
      601 acctcgtgaa gtaggtgtaa ttgcagttgc taaaaacgat ttaaaagata gttatacctt
      661 tttgaaaaag gagaaaccca tttttatatc cgtaatcttt ttggtttgca ttttcaattt
      721 ggttttaagt gctgttttaa ttgttggtct gcctatctta atttctgaag ttttaaaaat
      781 gccagataca ctatatggtt tttcacaatc agcattatca ttaggtggtt tatgtggtgg
      841 tattttaaca gctcttgttg cttcaaagtt aaaactaaaa aacctttata ccttgttact
      901 tatttgttct gtttctgttt tacttatggg aatttcgcta tttttagaat tgcctgcaat
      961 agtttcctac tgggtagtta cagtgatgtg ctttgtggct atgggtgtat ctactatgtt
     1021 tgttgttcaa atttacactc ttgttcagac acaaacacca ccgcaattag taggaaagat
     1081 aatggctacg ctggtagcag ttgctatgtg cggtcaacct attggacaaa tggtttacgg
     1141 tattttattc gatgtattta tacaagaaac atgggttgtt atgtttgtag cttctattgc
     1201 ttcaatcatg atttcaatat attcaaaaag aatttttcaa aagttagaga tataatacaa
     1261 ggggttaaat agtatgttag gctaaaaaca atatataaaa
//
LOCUS       DADVXK010000225         1298 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.234, whole genome shotgun sequence.
ACCESSION   DADVXK010000225 DADVXK010000000
VERSION     DADVXK010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.234"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..109
                     /locus_tag="KB909_002898"
     CDS             <1..109
                     /locus_tag="KB909_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBB6838844.1"
                     /translation="DIDSEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            114..1061
                     /locus_tag="KB909_002899"
     CDS             114..1061
                     /locus_tag="KB909_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBB6838845.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          421 a          186 c          276 g          415 t
ORIGIN      
        1 agatattgat agtgaagaag attttaaatg gttagaattt ttgtttccta aatttttaga
       61 agattcttcg gagcttcaag atatctataa ttatttatat cggaggtaaa aggatgagct
      121 gttatcttat caccggtggg gctggcttca ttggttctac cttagccaat catttaggag
      181 aagaacatgt ggtaatcgtc gtcgatgact tatcaatggg aaaagtagaa aatcttgata
      241 tgacgaaaaa tatcactttt attgagggag atgtcgctga gaaatccttg atggaagaga
      301 tcatgaaagc taataaattt gattatatct ttcatttagc agcagttgct agtgtggcag
      361 attcagttgc ccgaccagta gaaacacatc gtgtgaattt tgaaagtgta ttaatgattt
      421 tagaattgat ccgcaagtat caacctgatt taaaacggat cgtgtttagt tcttcagcgg
      481 ctgtttatgg ggatgaaccg actttaccaa aaaaagaaga gtccgtgatt cgcccattga
      541 cgccttatgc ggttgataaa ttcgctgcag aacaatatgt gctagattat tgtcatttat
      601 atgatgtacc cggtagcgca gttcgttttt tcaatgtcta tggtccaaat caaaatccga
      661 attctccata cagtggtgtg atttctattc tcgtagatcg ctataagaaa caaatcgtag
      721 gagaagcaac ttcatttaca ttatttggtg atggaagcca gtctagagac tttgtttata
      781 tagatgatgt aatccaagca ttacttttag ttgcgaatga ggaagctgca ctggggaaac
      841 aattcaatgt tggaacgggt aaagcaacca cacttttgga attgattcat gcaatcaatg
      901 aaattctcgg tgtagaattg acacttgaat acaaagaaga gcgttcgggt gatatccatg
      961 actctctagc agatattact aagatccagt caattggcta tcaaccgaaa tatggtattt
     1021 taagtggaat gactaattat ttgaaaactg aaatcaatta aaacatacta agataagatt
     1081 agagggtaaa ttcaggctct ttgtcaataa ggactgatga gttttgtaaa atcaaatctg
     1141 ggatagaagg gctctttgtc aaatgatgtt ggtaaagaga aatcttagaa taatttggac
     1201 agaacagaaa gaagaaaacc tctttctgtt ctgtttattt ggttaaaaat gttttgccat
     1261 gacgaatcat aattcgtagt ttgaaattgt aaaagttg
//
LOCUS       DADVXK010000226         1276 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.235, whole genome shotgun sequence.
ACCESSION   DADVXK010000226 DADVXK010000000
VERSION     DADVXK010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.235"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..451)
                     /locus_tag="KB909_002900"
     CDS             complement(<1..451)
                     /locus_tag="KB909_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6838846.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            675..>1276
                     /locus_tag="KB909_002901"
     CDS             675..>1276
                     /locus_tag="KB909_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6838847.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKI"
BASE COUNT          439 a          208 c          188 g          441 t
ORIGIN      
        1 aatttgtaat aagttcgtat atgttttgcg gtgtttcttg tttcttgtaa ttttccacga
       61 atgtttcatc catgaataaa ttcataaacg cttgaagtaa tcctacttgt tcttttggtt
      121 ctttgattcc taaaaaaaat agattttcta cagtcatttc ctgattatcc cccatttgat
      181 aaaaataaat tgggttcttc agctgcataa caaaaacaaa tggcttttcg acatattcac
      241 attccgaatg tggcagcgcg atatttaaat acttagtaat caatccagta ggaaattctc
      301 tttctcttgc aatcagtcca ttcaaataat tctcattgac gtaccccatt ttttctaatt
      361 gttgtgcagc gattaaaaaa gcttcttctt tattttttac ttctaccgct aattgaatca
      421 aactaggaac gaacatctct ttatatttca ttccaacctc ctcctttttg attaagtttg
      481 ttaatttatt gttctactaa attcatcttt gttttacaag aacattatat ttctgttagt
      541 ttgttttgtc aacgctttca aaagaaattt attttgttaa atttgatcta cttgaaaata
      601 aaatcgttta tctatataat taagaagaac aaagtcgaac aaaaattgac ttttatgtta
      661 aaggagtaat tcatatgctg aaaaaagaaa gacaagaaca aatcattaca ttattagaga
      721 aagattttta tttaactaat tcagaaatcg ctaacaaatt aggcgtatca gaaatgacca
      781 tacgccgaga tgtcactgaa ttagcaaaaa aaaataaagt aaaaaagcta tatggtggcg
      841 ttgaacgaaa ggaaccttat aatcgagaac tatcgactca agaaaagatt gatacgaatg
      901 tagccgaaaa aaaatatatt ggtcaagtca tgaacagtat gattcccgat aattctacta
      961 tttatgtcgg tgctggaaca acgatcctat atgcacttcc tttcattcaa aagaaaaatc
     1021 tatttgtaat tacaaacagt ttgattgctt tcaactattt aaagaatcat acaagttatc
     1081 ggattttact tactggtggc gaattttctc ctattacaga agagttcatt ggggaagttg
     1141 cagaaagatc ttttgaaagt ttgaatgtcg atatctcttt cgctgcaaca aacggcatat
     1201 ttgataacaa tgtgacaacc gctcaattta ttgagggaaa tattcagaac gcagcgctca
     1261 atgcagcaaa aatcaa
//
LOCUS       DADVXK010000227         1256 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.236, whole genome shotgun sequence.
ACCESSION   DADVXK010000227 DADVXK010000000
VERSION     DADVXK010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.236"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(233..382)
                     /locus_tag="KB909_002902"
     CDS             complement(233..382)
                     /locus_tag="KB909_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838848.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            844..1056
                     /locus_tag="KB909_002903"
     CDS             844..1056
                     /locus_tag="KB909_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838849.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          466 a          188 c          209 g          393 t
ORIGIN      
        1 attatacaga taataacgga atattatcat cgaaacagct aacaaaattg tcataaaaaa
       61 cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa gagagacaat
      121 ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt tacaaacgtc
      181 ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact ccttatctag
      241 attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg ttattttcgt
      301 tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg cggtattgca
      361 tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt agttcttgaa
      421 agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt ttgatgcaat
      481 taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc tattttcttt
      541 taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa tataaatcat
      601 atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg aacaacatag
      661 gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat agttatctaa
      721 aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt ttcaaataca
      781 aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa aagagggaat
      841 gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg agtatctcat
      901 gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta tgttgaaagt
      961 tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct cgtaaaattc
     1021 tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag aattcgcaag
     1081 aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca aaaagaaaaa
     1141 gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct attttagcta
     1201 ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc gtcaaa
//
LOCUS       DADVXK010000228         1251 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.237, whole genome shotgun sequence.
ACCESSION   DADVXK010000228 DADVXK010000000
VERSION     DADVXK010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.237"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            2..397
                     /locus_tag="KB909_002904"
     CDS             2..397
                     /locus_tag="KB909_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6838850.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            394..>1251
                     /locus_tag="KB909_002905"
     CDS             394..>1251
                     /locus_tag="KB909_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6838851.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDII"
BASE COUNT          496 a          141 c          241 g          373 t
ORIGIN      
        1 tatgttttgc aaagtatgtg atagaaaaga gggattctgt ggcttcagaa tagatatcaa
       61 agaattggca aaagtttctg atattttttt atttactaca ttacaagaag gaatgccaag
      121 atctatgatg gaagctatgg caagtggatt gccatgtata gcaagtaaaa tccgaggtaa
      181 tgtagacctt ttagtggaag gaaaaggtgg atatcttgtt ccagctaaag atgcagaatt
      241 agtagcagag tgtttgagag aactaatcaa taataaatct cttagaaagt atatgggaaa
      301 tgagaacctt tccagaatta aagaattcga ggttagtatc gtaaaaaaaa gaatcaaaga
      361 aatatatgaa gaagttatag gtgagagtgt aaaatgaaaa atccaatgtt ttcaataata
      421 gtacctatct attgcgttga aaaatatttg aaagattgct tagattcaat aagaaatcag
      481 acatttaaaa attttgaagc aatactagtt gatgacggta gtcctgacga atgcccagaa
      541 atatgtgact attattccca aatagatgga cgtttaaaag taattcataa gaaaaacggt
      601 ggaataatag atgcacggaa aacaggagtc actagtgcta tgggagagta tatagttttt
      661 ctagatggtg atgattggct tgcaaatact tatttagaaa aatatgcgga agtaattact
      721 aagtacaatc cagatataat atgtagtggg tattttgcat cacgttccaa caaaattaga
      781 aaaagagaat tgtcttgctc gtttggatat tatgacaaag ataaaattat aaatttgatt
      841 tatcctaaat taattgagga tgaacatgga gagtatttta gaccacaatt atgggcaaaa
      901 gcttttagaa ctactctgta caaggaacaa caacaagtat ctgggcaagt tagtgttggt
      961 gaagatcatg catgtacaaa accatgtatt taccatgcaa attcgatata tatgatggaa
     1021 aaatgtttat attattacag aataaacgaa aattctataa caaaaaaacc acaaccatat
     1081 tattgggaag gaccaaaggc tattggagag cattttgaaa agcagattga tatgaataag
     1141 tatgattttc aagatcaagt atatagaaat gttacacaca atttatttaa tgttgctgtt
     1201 tcacaattta ataaacagga caaatattta aatataaaaa aagatattat a
//
LOCUS       DADVXK010000229         1248 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.238, whole genome shotgun sequence.
ACCESSION   DADVXK010000229 DADVXK010000000
VERSION     DADVXK010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.238"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            316..570
                     /locus_tag="KB909_002906"
     CDS             316..570
                     /locus_tag="KB909_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6838852.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="KB909_002907"
     CDS             571..888
                     /locus_tag="KB909_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6838853.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          435 a          205 c          249 g          359 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtattt
//
LOCUS       DADVXK010000230         1219 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.239, whole genome shotgun sequence.
ACCESSION   DADVXK010000230 DADVXK010000000
VERSION     DADVXK010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.239"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..460
                     /locus_tag="KB909_002908"
     CDS             <1..460
                     /locus_tag="KB909_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBB6838854.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="KB909_002909"
     CDS             469..696
                     /locus_tag="KB909_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838855.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DADVXK010000231         1216 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.240, whole genome shotgun sequence.
ACCESSION   DADVXK010000231 DADVXK010000000
VERSION     DADVXK010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.240"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(54..425)
                     /locus_tag="KB909_002910"
     CDS             complement(54..425)
                     /locus_tag="KB909_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838856.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(427..828)
                     /locus_tag="KB909_002911"
     CDS             complement(427..828)
                     /locus_tag="KB909_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838857.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(842..>1216)
                     /locus_tag="KB909_002912"
     CDS             complement(842..>1216)
                     /locus_tag="KB909_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838858.1"
                     /translation="DVESQQFGTNVINKVINPALSINAPLIPTALSFSVTAVVSEIED
                     TEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLVEEAGEHYAVVK
                     FNGTEIGRQIFDIKVNKPVEKN"
BASE COUNT          390 a          218 c          156 g          452 t
ORIGIN      
        1 gaaagataca aagattaaat aaaaaaataa caaacaaact cgcttgaaat tcattaggtg
       61 agtttgttta ttattttttc tgcttctcga ttcatcagcg ccatatctgt tttcgtaatg
      121 gtttcattag gaatatagtc agcacatttt cttttctcta acattctata cccactatta
      181 tgtattccta aggtattcaa ttccttaact gttgaaaaca aattccaaac ggtttggtgg
      241 cttccttttc cgctacttcc attataaata atatcataat tttctttcaa atactcatca
      301 gattttttaa aagcactgta gtatgctctt gaaacagcag ttcttctata agattcttta
      361 gaattatatt tatcatctga ttcaatttgt ttggaaatag ataaatattc attaaagtca
      421 aacattttat tcccccaaag ttgctactac agatttcccc atatatttat agtcagataa
      481 tacattatcg agagtatcca aaacatcgta atctgaggaa aacaattcag atgttgtttt
      541 gataacaaag aaatacaagt ttaaatcttc atcatatttt atattgattt cagcttttct
      601 ttttaaaacc gtatttatca catcaaaaat tttgccatca ttacttgaaa ttgtgttaat
      661 ctcatttttt gtagtaatta caagttgatt atcattttta gttttcggag tagaacttgc
      721 atccacaaca actggagatg ctagaattac cgatgcgcaa gcaaaaatcg cagcaaaatt
      781 tattaagcta ccactccgat gtgtatttga tggtactata tcaagcatcc gtatcgtctc
      841 cttaattttt ttccactggt ttgttgacct tgatatcaaa gatttgcctt ccaatctcag
      901 ttccattaaa tttaacaaca gcataatgct ctcctgcttc ttcaaccaag acatttctgg
      961 cgtttatatt aaagtttata tcgttaactt gaggaggcaa gcttaccgat acttcacccg
     1021 tagaaaaaat ttgtttttca ttcttgttta aaacttcaat ttctactatt tttatctttt
     1081 ctgtatcctc tatctcagac accacagctg ttacagaaaa tgataaagca gtaggaatta
     1141 aaggcgcatt aatagaaaga gctggattaa ttactttatt aataacatta gtgccaaatt
     1201 gctgactttc tacatc
//
LOCUS       DADVXK010000232         1206 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.241, whole genome shotgun sequence.
ACCESSION   DADVXK010000232 DADVXK010000000
VERSION     DADVXK010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.241"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(38..523)
                     /locus_tag="KB909_002913"
     CDS             complement(38..523)
                     /locus_tag="KB909_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBB6838859.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(525..>1206)
                     /locus_tag="KB909_002914"
     CDS             complement(525..>1206)
                     /locus_tag="KB909_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838860.1"
                     /translation="INDLSRFSINVVEVDDYSEITDILKSIRKKYLRKTIFISGSAVD
                     YTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGNSIVSGVLKQRRNLRKNNIQD
                     VLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLESGEIVTADGMIEEFELSVQN
                     ENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQALEKLDTEGEVDKKVEQIVS
                     LINSIQED"
BASE COUNT          377 a          256 c          124 g          449 t
ORIGIN      
        1 aataacatgt cattagatag tagacagttc caactcttta tttacctttt ttgtatgctg
       61 cactgtcaat ccaagttcct aaattgttgt atccatcatc acttatataa tcatattggc
      121 catcaataat ttcgtcaaac cacaaatatt ctccatctgg tttttgccca attattttaa
      181 ttactgattg actagtagtt gtcatctggt taaaatcttt tattttacct atattaacgg
      241 ccaaaatagc atttcctcgc ttataactct cctggatttc atatttaaca tattctcgat
      301 caagagtttc tttacctatc agcaccacag tcactgatgt tccaattaat tgattatcta
      361 tccagttttt tatagcaata tctccattac gtttaacttt ctcaaattca gccttatcta
      421 caaaaccagc ttcctttgtt cctcgcaaag tccagctgtt tctaactacc attgctcttg
      481 ttacatctgc ataatggaaa ctaaaaaaaa cccttctcac catattaatc ctcctgaata
      541 ctatttatta aactgacaat ttgttcaact tttttatcta cttctccttc agtatctaat
      601 ttttctagcg cttgaaattt actttttaag gaatcatcaa aataatcact gaaattctct
      661 tgaatcttat caaacaaaac cttacttgca cctttggtaa atccaatcgg aactactata
      721 ttttcatttt gaacagataa ttcaaattct tcaatcattc catctgctgt aactatttca
      781 cctgattcaa gtttgtttcc aaaaacaaaa atactaatcc cagactctgc aataatgttt
      841 tctcgatatc ttctccactc atgaggcata tcaaggggaa gtggtcttaa agaaagtacg
      901 tcttgtatgt tattttttct taaatttctt ctctgcttta gaactcctga aacaatacta
      961 ttaccaattc caagtccgta acctgatact attctataac cggattcaga aagcctatat
     1021 gctaatttct cgacaaattt taatcctttc gattcagatg taaatggagt ataatcaaca
     1081 gcacttcccg aaataaaaat agtttttctc aaatactttt ttctaatact tttcaaaata
     1141 tcagtaatct cagaataatc atctacttca acaacgttta tcgaaaatct ggacaaatca
     1201 ttgatt
//
LOCUS       DADVXK010000233         1195 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.243, whole genome shotgun sequence.
ACCESSION   DADVXK010000233 DADVXK010000000
VERSION     DADVXK010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.243"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1076
                     /locus_tag="KB909_002915"
     CDS             <1..1076
                     /locus_tag="KB909_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6838861.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DADVXK010000234         1177 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.244, whole genome shotgun sequence.
ACCESSION   DADVXK010000234 DADVXK010000000
VERSION     DADVXK010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.244"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>1177
                     /locus_tag="KB909_002916"
     CDS             <1..>1177
                     /locus_tag="KB909_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838862.1"
                     /translation="ISLSIKDATDRASKETFANITNSFSMEINRQVNPGTPRGGGNVK
                     GEDIKKISQTDSIDSYVKRINSVADLVDYDIIETQETLANQSPERAKNFKRTVMLTGV
                     NDSTKETKFVSEAYKLVEGKHLENEDKNKILMHKDLAEKNNLKVGDKIKIKSNLFDAD
                     NEKGADETVEVEIKGLFDGHNSGGVSAAQELYENTLITDIHTAAKVYGNTEDTAVYQD
                     ATFFVKGDKNLDSVIKDLGKLDINWREYNLIKSSSNYPALQQSISGIYSISNKLFFGS
                     LIFAGVVVSLLLFLWMNARKKEIAVLLSLGISKLEIFGQFLIEMVFISIPAFVGSYFL
                     AQYTADKLGNNILNKVTGDIAKQIAKQSASSQLGGGAEAEGFNKTLSSLDINVLPKFM
                     "
BASE COUNT          473 a          142 c          211 g          351 t
ORIGIN      
        1 cattagttta tctattaaag atgctacgga cagagcttca aaagaaacat ttgctaatat
       61 aacaaatagt ttttctatgg agataaatag acaagtaaat ccaggaacac ctagaggtgg
      121 gggaaatgta aaaggtgaag atattaaaaa gatatctcaa acagatagta tagactccta
      181 tgtaaaaaga ataaacagtg ttgcagattt agttgattat gatattattg aaactcaaga
      241 gactcttgcg aatcaatcac ctgaaagagc aaagaatttt aaaagaacag ttatgttaac
      301 tggggttaac gactcaacaa aagaaacaaa atttgtatca gaagcatata aattagtaga
      361 aggaaagcat ttagaaaatg aagataaaaa taaaatctta atgcataaag atttagctga
      421 aaaaaataac cttaaagttg gagataagat aaaaataaaa tctaatttat ttgatgctga
      481 taatgagaaa ggtgcagatg aaacagtaga agtagaaatt aaaggtctat tcgatgggca
      541 taatagcggt ggagtaagtg cagcacaaga actatacgaa aatacattaa tcactgatat
      601 tcatacagct gctaaagttt atggtaatac cgaagataca gctgtatacc aagatgcaac
      661 attctttgta aaaggtgata agaatcttga tagtgtaata aaagatcttg ggaaattaga
      721 tataaattgg agagaatata atttgattaa aagttcatca aattaccctg cattacaaca
      781 atctatatca ggtatttact caatttcaaa taaattattt tttggctcat taatatttgc
      841 aggagttgta gtttcattat tattattctt atggatgaat gctagaaaga aagaaatagc
      901 agtattacta tcattaggta tatcaaaatt agaaattttt ggtcaattcc taattgagat
      961 ggtatttata tcaatccccg cattcgttgg ttcctatttc ttagctcaat atacagctga
     1021 caagcttggg aataatatat tgaataaggt tactggtgat atagctaaac aaatagctaa
     1081 acaatctgca tctagccaat taggtggtgg ggcagaagct gaaggattta acaagacatt
     1141 atcaagttta gatatcaatg tattacctaa attcatg
//
LOCUS       DADVXK010000235         1165 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.245, whole genome shotgun sequence.
ACCESSION   DADVXK010000235 DADVXK010000000
VERSION     DADVXK010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.245"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..969
                     /locus_tag="KB909_002917"
     CDS             <1..969
                     /locus_tag="KB909_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6838863.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          394 a          207 c          232 g          332 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccata aatagtcaca
     1081 ctccaagcta tgcgataaca ggtttgttgc cacacattct actggttgat tgtttatggc
     1141 tttatgtggc aacaaccagt accct
//
LOCUS       DADVXK010000236         1147 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.246, whole genome shotgun sequence.
ACCESSION   DADVXK010000236 DADVXK010000000
VERSION     DADVXK010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.246"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            318..>1147
                     /locus_tag="KB909_002918"
     CDS             318..>1147
                     /locus_tag="KB909_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6838864.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          404 a          156 c          191 g          396 t
ORIGIN      
        1 tattttaggt ttcatattat ataaattaat aatatactac catttgttgg tagtataatt
       61 taaaggtaat aagttattct tttattacta tgtttgggtt ttatagcaaa gaaagtttaa
      121 taagagtttg gacctagcaa acaatattaa tgaggtcatt aaatcttatt atctttagtg
      181 atataacgaa atatctacac agacaaaatg atagcgtaaa atattttgtg taaatagata
      241 tttagggtag aaaaaaagaa agtccattct gtaaaattaa agttaccaca accgaaattt
      301 tataggagga ctttctcatg cccaatttta ctacagaaat tatggaaaca ctaatcaata
      361 aaggtgattt agatgaatta tttcgatgtc atttagaatt agctgttaat tcattattgc
      421 aggctgaatt aacagctttt cttgattatg aaaaatatga tcgtgctggg ttcaattcag
      481 gtaattcccg taatgggaat tattcacgtt cattcagaac agagtatgga gaattaaatt
      541 tggtaattcc tagagataga aatggtaagt tttctcaaca aactttacct gcttataaaa
      601 gaaccaatga ctctttagaa accactatta ttcagctatt tcaaaaagga attactatgt
      661 ctgaaatctc tgaattgatt gaaaaaatgt acgggcatca ctatacgcca caaaccattt
      721 caaatatgac taaaatagtt tctgaagata ttattgcctt taaagaaagg tccttagaat
      781 ccagatactc tgtcattttt atggatgcta ctcacattcc tttaaaaaga caaactgttt
      841 caaaagaagc agtttatatt gtaattggca ttcgattaga tggaaccaaa gaggttcttg
      901 ggtttagtct tgctccaact gaatctgctt atgtttggaa agagattctt caagacctaa
      961 aagaccgtgg tttaaaagag gttttattag tcgtaactga tggtttaagt ggcattaacg
     1021 atagtattca tagtgtttat ccaaatgctc aatttcaaca atgttgtgtc catatatcta
     1081 gaaatatcgc tcataaggtt cgtgttagtg atcgacaaga aatctgtagc gatttcaaat
     1141 tagttta
//
LOCUS       DADVXK010000237         1114 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.247, whole genome shotgun sequence.
ACCESSION   DADVXK010000237 DADVXK010000000
VERSION     DADVXK010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.247"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(158..388)
                     /locus_tag="KB909_002919"
     CDS             complement(158..388)
                     /locus_tag="KB909_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838865.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(638..838)
                     /locus_tag="KB909_002920"
     CDS             complement(638..838)
                     /locus_tag="KB909_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6838866.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          396 a          176 c          166 g          376 t
ORIGIN      
        1 aagtagttct tattagaata gtagagatta attaataagc tatcttcgat tgctaaaaag
       61 aaaacttctg aatcccacac cttataaaaa tctttgacaa atctattcga aggatcaaat
      121 ttaaaccata attgcgtctc attaaaaagc ataaccatta ctccgatcta tttttaaact
      181 tagtctctac ctctaatata tatcgagttt ttattttgcc ttcagagaat actgtttctt
      241 tttttgcagt tacaggttgt ttattttcgg aaaaagctaa tatagctaaa attgaaacat
      301 ccatctggaa tttgtctttt tcgttgcttt gctcataaaa atctgcatat tcatcactaa
      361 tattttttct aataaattct tccatcataa agatcacctc gaaaagagta tacgaacaaa
      421 cgttcttttt gtaaaggtgg aatttattat actaaataaa taggtgaaca agtacttgtg
      481 ccaaattatg tgccaaaaaa aatcgaattt aataaaacac aaacaaaaag aaatcctatt
      541 atgataacat ttcttataat aacaaacaca acagaagacg tgtaatagtt agtcaggaac
      601 gtacaaataa cccctgtatc ctttgcggta cagggggtta ttttgtataa gtagacattg
      661 tagtttctaa actgctatgt cctaaacgtt tcgatacgct aagtatattt actccttgat
      721 aaagtaaaat agatgcatgc gtatgtctta gtccatcaat aaacagtcga agagaaaata
      781 gggaaaaatt gattactaaa gaaaaactta ctaggtcgac ggtgtagttg attttcatac
      841 ttcaatagat tcgaattaaa cgatttcgat tggcttatac cagtcctatc caacgaaaga
      901 tatatcgttc ttaactctag cggtataact tgaagcttta cgtaaagcca atgggaatga
      961 actggagatg actttttatt atttttagta atagctgatg ggttaatact tacaactttc
     1021 cttttcaaag taccatataa aaaaacggtg gggttgttta gcgaaataaa ggatctaagc
     1081 caatagctta gatcctttat tctatgcttt atat
//
LOCUS       DADVXK010000238         1108 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.249, whole genome shotgun sequence.
ACCESSION   DADVXK010000238 DADVXK010000000
VERSION     DADVXK010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.249"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..375)
                     /locus_tag="KB909_002921"
     CDS             complement(<1..375)
                     /locus_tag="KB909_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6838867.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILF"
     gene            complement(377..1096)
                     /locus_tag="KB909_002922"
     CDS             complement(377..1096)
                     /locus_tag="KB909_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6838868.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
BASE COUNT          390 a          214 c          122 g          382 t
ORIGIN      
        1 aaataaaata tgaaataaat ccgttgagct atttgcaact cctataagga taactcctag
       61 tgctaaaaaa gaactgaaag taataccaat tgctgtatct ccttttatta cactattgct
      121 ttttataaaa gtaataatga tagaagctaa tagaccaaat acaatcgcac caataaaaaa
      181 attaatacct aaaatataag aaattgctac tcctggcaaa acagcatgag aaatagcatc
      241 acccataaga gacattcctc ttaaaataat aaaacaacct actgttccag aaacaatccc
      301 tataactaca gatgtaatta gagcattctg taaaaagtga aagtcataca gaccattaat
      361 aaaattttga agcatattat tccccctctc caataaatat agtatctcca taggcttttt
      421 ttaaattttc ttcattaaat acagattcta cacttccgtg agcaattaga tttcgattca
      481 aaagaataat attatcaaaa tacttcttta ccttgcttaa atcatgatgc acaattagca
      541 ctgtttttcc ctgatgtttc aattttttta acgtatccat aattattcgt tcactaacta
      601 agtctatccc tacaaatggt tcatctaaaa atatgaaatc cgcattttga gcaagacatc
      661 ttgctaaaag tacacgttga aattgtcctc cagataattc tcctatttga tgattagaat
      721 attttcccat atcgaccttt tccaaagcct ttgaaactct ttgccattct gcatttttaa
      781 ttctttgaaa aactttcatt ccggcatatg ttcccataga tacacattct tttactttta
      841 ttggaaaagt aaaatcaata tcagcttttt gctctacata tgcaatcttc accagttttt
      901 tattgatatc ttcattatta atggagacct ctccctgatg agggataata tttaacattg
      961 ctttaagcaa tgtggatttt ccagcaccat ttggaccaat aatacctgtt aaagcacctt
     1021 cttgtatttt taaagaaatc tcgttcaatg ctaaaaaatc gttataacaa acattaagct
     1081 ttttcacttc taacataact ttctcctt
//
LOCUS       DADVXK010000239         1095 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.250, whole genome shotgun sequence.
ACCESSION   DADVXK010000239 DADVXK010000000
VERSION     DADVXK010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.250"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(60..278)
                     /locus_tag="KB909_002923"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="KB909_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="KB909_002924"
     CDS             complement(544..738)
                     /locus_tag="KB909_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838869.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="KB909_002925"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="KB909_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          380 a          187 c          158 g          370 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaac
//
LOCUS       DADVXK010000240         1070 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.251, whole genome shotgun sequence.
ACCESSION   DADVXK010000240 DADVXK010000000
VERSION     DADVXK010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.251"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..655)
                     /locus_tag="KB909_002926"
     CDS             complement(<1..655)
                     /locus_tag="KB909_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6838870.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     "
     gene            789..>1070
                     /locus_tag="KB909_002927"
     CDS             789..>1070
                     /locus_tag="KB909_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838871.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVV"
BASE COUNT          399 a          185 c          184 g          302 t
ORIGIN      
        1 gttcaagagg atcaagtggt tcaaatgttt ctgtagtctg ttttgcttcc aattggggca
       61 aaacagatcc aatttccaga tacttcactt tattcaatgt ataagataga atagaacagc
      121 taagtaatgt atacagaaaa tgtgtgagat ccaaataaag caaggagaca actaaaatac
      181 caaaagtaat caagaaaaga cttttgccaa tcttaatatg aaaatatttt tcaatggctt
      241 gataaatgat atctgttccg cctgtgcttc cgccgaatcg aaagacgaga ccgcaaccaa
      301 tgccagaaag aatacctgtc atcaaactat tgatcagtag actatctaca gcaaaatgta
      361 tatgaaggct ctcccataaa tgtaaaaaga aaactagcgc aaatgttccg acgatcgtcc
      421 ggagaaaagc gtgttttcca aaaagaaaca atgagataag caataaaggt aaattaaaaa
      481 gcagtgaagt gacagaagga gcgaatccaa aaagattatg caaaagcaaa gcaataccag
      541 taaccccacc atctgccagc ttagatggaa tattgattcc tgtcacagct aatccgtaga
      601 ttcctgcgcc taaaatgatt ccgcacaatt ctgtaaataa atttaatttt ttcatttcta
      661 gcctcttttc ttttgaaaat tttcagcaac ttctttatta tactgactta tactcttact
      721 tcaagaggaa aatgaaaaaa aattattttt ggctgtttct ttttatttat caaataagga
      781 gtggaaaaat gcgagcagca gacttattga caattcttac aaaatcaccc aaaaaaacag
      841 agtatcaagg agtttttttg gctcaagaac aaaaactggt gcctgtgaca atggtccaga
      901 taaataaagc aaatcaattt atctttttat ttgaacacgg caaagcacca cttgctatga
      961 aagacatctt tctttttttg atgaagaacc gtgagaaagc tgtttattat cagtcaaaag
     1021 aagaactcat tcctctttat ggagtgaaag agatagaaaa taaagtggtg
//
LOCUS       DADVXK010000241         1060 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.253, whole genome shotgun sequence.
ACCESSION   DADVXK010000241 DADVXK010000000
VERSION     DADVXK010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.253"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            188..>1060
                     /locus_tag="KB909_002928"
     CDS             188..>1060
                     /locus_tag="KB909_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6838872.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSAASKRNN"
BASE COUNT          365 a          184 c          193 g          318 t
ORIGIN      
        1 ttgagactac tatatgcgtt tttttgttga tttaccaaca tgtttagaca ttttcctcta
       61 ggaaaaaatt aactagcacc acgggttttt attacgccga ttgtaaaatt aagctagaca
      121 actaaaaaag tcatttgtgc tacactcaaa atagttccga ccaaagaatt ataaggagtg
      181 agtacaaatg acctataccc atcttacaac ggatgaactt gtaataatag agtcttattt
      241 caaaatgaat caatctgttg ctaaaactgc ccattgcttg aatcgttcaa gacaaacgat
      301 ccataaagta tatctgttct tcaagcaagg aaaatcagcc ttagaatatt atcaacagta
      361 taagaaaaac aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga
      421 atatattcaa agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc
      481 gtttcctatt agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga
      541 ttcttctgac ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg
      601 aaaacaaact ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa
      661 tgagtttggt caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat
      721 taccttagtt gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc
      781 gattgatatt gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa
      841 atccatcact tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa
      901 tgatattgcc atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa
      961 ttctaacgga ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga
     1021 tgaatttttt attcaatctg ccgcatctaa acgaaataat
//
LOCUS       DADVXK010000242         1047 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.254, whole genome shotgun sequence.
ACCESSION   DADVXK010000242 DADVXK010000000
VERSION     DADVXK010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.254"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            281..973
                     /locus_tag="KB909_002929"
     CDS             281..973
                     /locus_tag="KB909_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6838873.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          447 a          147 c          177 g          276 t
ORIGIN      
        1 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
       61 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
      121 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
      181 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
      241 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
      301 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
      361 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
      421 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
      481 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
      541 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
      601 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
      661 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
      721 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
      781 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
      841 gaaattagac gaagcaactg ctgaaaactc aagctggaaa caatatattc aaaagttaga
      901 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
      961 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     1021 tatactaagt agttcagttt tggagta
//
LOCUS       DADVXK010000243         1045 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.255, whole genome shotgun sequence.
ACCESSION   DADVXK010000243 DADVXK010000000
VERSION     DADVXK010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.255"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="KB909_002930"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="KB909_002930"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6838874.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DADVXK010000244         1035 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.256, whole genome shotgun sequence.
ACCESSION   DADVXK010000244 DADVXK010000000
VERSION     DADVXK010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.256"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..>1035)
                     /locus_tag="KB909_002931"
     rRNA            complement(<1..>1035)
                     /locus_tag="KB909_002931"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DADVXK010000245         1000 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.257, whole genome shotgun sequence.
ACCESSION   DADVXK010000245 DADVXK010000000
VERSION     DADVXK010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.257"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            369..1000
                     /locus_tag="KB909_002932"
                     /pseudo
     CDS             369..1000
                     /locus_tag="KB909_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DADVXK010000246          999 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.258, whole genome shotgun sequence.
ACCESSION   DADVXK010000246 DADVXK010000000
VERSION     DADVXK010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.258"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(53..787)
                     /locus_tag="KB909_002933"
     CDS             complement(53..787)
                     /locus_tag="KB909_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6838875.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
BASE COUNT          349 a          206 c          182 g          262 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatata
//
LOCUS       DADVXK010000247          986 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.259, whole genome shotgun sequence.
ACCESSION   DADVXK010000247 DADVXK010000000
VERSION     DADVXK010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.259"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>986
                     /locus_tag="KB909_002934"
     CDS             <1..>986
                     /locus_tag="KB909_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6838876.1"
                     /translation="LEPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITD
                     SEYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQL
                     DDTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTG
                     KKNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVG
                     SIAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFY
                     ENFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          263 t
ORIGIN      
        1 ttagaaccag gcgattttat catgagtggc gctggaacaa ttgggagaat ttcaagagta
       61 ccaaagcaaa taaaaccggg tgtattcaat caggctttga ttagacttag aataaataaa
      121 gaaatcacag attcagaata ttttattcaa tttattcgtg cagattttat gcaaagaaaa
      181 ctcacaggag ctaatccagg ttcagcaatt acaaatctcg taccaatgtc agaagtgaaa
      241 aaatggatag tacaatttcc aatattagaa gaacaaaaga aaattgggaa cttcttcaaa
      301 caactggacg acactatcgc tcttcaacaa cgtaagctag atttattaaa ggaaacgaaa
      361 aaaggattct tacaaaaaat gttccctaaa aacggagcaa aagtgccaga aattcggttt
      421 cctggattta cggaagattg ggaacagcgt aagttcaaag agtttagtaa gaagactgga
      481 aaaaagaaca cgaaagattt agacttccct gcctattcgg taagtaataa agcaggttta
      541 atttctcaaa cagaacagtt tgatggtagt aggttggatg atttagaaaa aacaaattat
      601 aaattcgttg aaccaaatga attcgcctat aatccagcaa gagtaaacgt aggatcaatt
      661 gcatttaaca atcttggtat gacggtcatt gttagctctc tttatgtagt tgtgaaaatg
      721 agcgaggact tagataatga gttcatactt cagtttatca agtcaccaac atttatcaaa
      781 gaggtcaagc gcaacactga aggaagcgta cgagaatact tattctatga gaatttcgct
      841 aatatcaagt ttccttttac taggaataaa gaggaacaac aaaaaatcgg cgctttcttc
      901 aaacaactcg acgacacgat cgctcttcat caacgtaagt tagatttgct gaaggaaacg
      961 aaaaaaggct tcttacaaaa gatgtt
//
LOCUS       DADVXK010000248          966 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.260, whole genome shotgun sequence.
ACCESSION   DADVXK010000248 DADVXK010000000
VERSION     DADVXK010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.260"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(17..90)
                     /locus_tag="KB909_002935"
     tRNA            complement(17..90)
                     /locus_tag="KB909_002935"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Ile,seq:cat)
     gene            complement(645..959)
                     /locus_tag="KB909_002936"
     CDS             complement(645..959)
                     /locus_tag="KB909_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838877.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          356 a          150 c          152 g          308 t
ORIGIN      
        1 caattggcta cattaatgta ccctgtagga ctcgaaccta cgaccggacg gttatgagcc
       61 gtctgctctg accaactgag ctaagggtag tggttgttgc cacataaagc cataaacaat
      121 caaccagtag aatgcgtggc aacaaacctg ttatcgcata tcttggagtg tgactattta
      181 tgagtgatag tgaagatatg cgtctccata tatgtatggt tgagacagat aaacatgtat
      241 gaaaaacgtt gttaaatcaa cgttttttta ttttggtcaa ggagagaaaa gtagagaaat
      301 acaaaatttt ttgcattgat tttgcattca aaaaaacatt caaacattta gaaatcccca
      361 atacgtattc aggaaaatct attttaaggt ttacaaaaag aacttttgtt cgtacactct
      421 ttttgaggtg aacttttatg ctgatggaag gaaaaacaca attatggttt aagcatgttc
      481 cttcaaataa gttttttaat tataaactct agagaaatta attcatccta acataaaata
      541 attgttcact caaaagtttt tctagaacaa ttaaaacagc aggcttcaca ttcgctatac
      601 atttgtaaga agtaataatt cctgtactaa aaggcataat tgctttaatt attttttgac
      661 ttctcttcaa acacaagaag tagttgtgta ataattgcag aaataaggat tccaataata
      721 gatataaaat ttgacatgga aacgtctata acattaaaag aataaagtgt tgaagaaagt
      781 aaactgattg aaataacccc tccgtaaaaa atagtctgtg aatataccca ctttttttca
      841 gaagacgtac ttcgtttggt tctaaaacct atccctgcat ttctactctt atcaaaaaac
      901 caaatattta gaagtaataa tattgctatt attaagataa aattactgta aaaatccaaa
      961 agctat
//
LOCUS       DADVXK010000249          963 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.261, whole genome shotgun sequence.
ACCESSION   DADVXK010000249 DADVXK010000000
VERSION     DADVXK010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.261"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>963
                     /locus_tag="KB909_002937"
     CDS             <1..>963
                     /locus_tag="KB909_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HBB6838878.1"
                     /translation="TSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQP
                     ITADDTEFVSSATKLDDIIENPGDNIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSL
                     PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHK
                     VTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDT
                     EFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVD
                     VSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          385 a          158 c          219 g          201 t
ORIGIN      
        1 aacaagtatt gaaagtggaa caacagtctt tgcagtgaaa gacggcgtaa gcttgccaga
       61 agataaactt ccagtgttga aagcaaaaga tggttataca gatgcgaaat ggccagaaga
      121 agcaactcaa ccaattacag cagatgatac agaatttgta tcaagtgcaa caaaattgga
      181 tgatatcatt gaaaacccag gggataacat tccggctggc tatcataaag taacctttac
      241 tgcaggagaa ggaacaagta ttgaaagtgg aacaacagtc tttgcagtga aagacggcgt
      301 aagcttacca gaagataaac ttccagtgtt gaaagcaaaa gatggttata cagatgcgaa
      361 atggccagaa gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc
      421 aacaaaactg gatgatatca ttgaaaatcc aggagaaaac attcctgcag gctaccacaa
      481 agtaaccttc accgcaggag aaggaacaag tattgaaagt ggaacaacag tctttgcagt
      541 gaaagacggc gtaagcttac cagaagataa acttccagtg ttgaaagcaa aagatggtta
      601 tacagatgcg aaatggccag aggaagcaac tcaaccaatt acagcagatg atacagaatt
      661 tgtatcaagt gcaacaaaac tggatgataa atctgacgct gacaaatata atcctgaagg
      721 tcaaaaagtg actacagaat tgaataagga accagacgca tttgagggaa ttaagaacaa
      781 agaagattta ccaaaagata ctaagtatac ttggaaagaa aaagtagatg ttagcgcagc
      841 tggaaataaa aaagggactg ttgtagtgac atatccagat ggatcatctg atgaagttga
      901 agtagatgtt acagtgacag acaatcgttc tgacgccgat aaatatgagc caacagtaga
      961 agg
//
LOCUS       DADVXK010000250          943 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.262, whole genome shotgun sequence.
ACCESSION   DADVXK010000250 DADVXK010000000
VERSION     DADVXK010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.262"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>943
                     /locus_tag="KB909_002938"
     rRNA            <1..>943
                     /locus_tag="KB909_002938"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DADVXK010000251          927 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.263, whole genome shotgun sequence.
ACCESSION   DADVXK010000251 DADVXK010000000
VERSION     DADVXK010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.263"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..788
                     /locus_tag="KB909_002939"
     CDS             <1..788
                     /locus_tag="KB909_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838879.1"
                     /translation="ALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKYYI
                     SLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLSR
                     RALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHK
                     DGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          341 a          145 c          168 g          273 t
ORIGIN      
        1 ttgctttgat tgatagtaaa ttcatcaaag ttcctaaatt gaagtcatta gtaagaatta
       61 agcttcatag acaaccaaaa gggattatca aatctgctac aatatcacgt cattctagcg
      121 gtaaatacta tatttctttg ttgtgtaaag aagaaattat cgaattacct aaaactaatt
      181 ccacaattgg tattgactta ggtattatgg actttgcgat tctttctgat ggacaaaaaa
      241 ttgataataa taaattcacg tccaaaatgg aaaagaaact aaagcgtgaa caacgcaaat
      301 tgtctaggcg tgctttattg gctaaaaata aaggtaccaa tctatttgaa gctaaaaatt
      361 atcaaaaaca aaaacgcaaa gtagctagat tgcatgaaaa agtaatgaat caacgtactg
      421 attttctgaa taagttgagt acagaaatga tcaaaaatca cgatattatc tgtattgaag
      481 acttaaacac aaaaggtatg ttgcgaaatc ataaattagc taaaagtatt tctgatgttt
      541 cttggtcaaa gtttgtgact aaattacaat acaaggctga ctggtatgga cgaaaaatca
      601 tcaaagtaga taaatggttt ccgtctagtc agatttgttc agagtgcgga cataaagatg
      661 gcaagaaatc tcttgaaatt cgagaatgga cttgtcctgt ttgtcatact catcatgatc
      721 gtgatatcaa tgctagtatc aatattctga ccgaaggtct aagactacat tctatgggat
      781 tggcttagat ccaatcatca agaaccgtag gaactacggg gatagcttgg taaataagag
      841 acaccgctgt tagtaaagaa atacgctatc aagtatgctc tattcccaag aagctcccac
      901 ttcaagcgtt aagaaccgtc aggttta
//
LOCUS       DADVXK010000252          923 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.264, whole genome shotgun sequence.
ACCESSION   DADVXK010000252 DADVXK010000000
VERSION     DADVXK010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.264"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(71..475)
                     /locus_tag="KB909_002940"
                     /pseudo
     CDS             complement(71..475)
                     /locus_tag="KB909_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(534..>923)
                     /locus_tag="KB909_002941"
     CDS             complement(534..>923)
                     /locus_tag="KB909_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838880.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          275 a          163 c          153 g          332 t
ORIGIN      
        1 cacgacctaa agatcgtgtc taattatgac tgtatcagaa aatatgatac caaacggatc
       61 tattcattaa ttaattgaca tagtttatct gttgctcttt tatgactgga taactgacca
      121 attcatgacg atccaagtct tctttattca tatttacagc agtaatttga ctgtcttcat
      181 acgtacgata ataataaatc cctttatcaa cgttacagca agaagaataa atcgtatatt
      241 cgtattttcc ttctccagta tcgcatactc ctttttgttg ctcgactgag cctagtatat
      301 gaaaaaattg actgatactt tcagattctg aatcacctga tgcagcattc attttagtaa
      361 atgtggcttt tacaaatcga gaaacagaag agagatctcc aggtaagccc aatcctccca
      421 tcccacgact ataaacattc aagctgatct ggtttgaaaa atgattttct ggtgttccat
      481 tgggagcgtc aataattttg tgtaaataaa ttgtcctcct gcaaaataat tagttactca
      541 gtaaacattg aaactaatgt atcggttacc tgttgaaaac ctttatggct tctgtttaga
      601 aatttttgat tgtatgtatc aaaaatgctg actagaaagc gttctagtga ttcttcattt
      661 tgaaactgct cttttctacg gctgtatctt ttaatttgct tattgaaaga ctcgattaga
      721 ttggttgagt aaatggttct acgaatgcta ggtggaaaat cataaaaagt taataagtct
      781 tggttttcta tgagtgactg cgtcacttta ggatagtttt tcttccattt ctcaatcatg
      841 ccggataaga aggtattcgc ttcttctttt gagttagctt gataaacagc cttaaagtca
      901 tcacagattt cttttcggtc ttt
//
LOCUS       DADVXK010000253          910 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.265, whole genome shotgun sequence.
ACCESSION   DADVXK010000253 DADVXK010000000
VERSION     DADVXK010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.265"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..888
                     /locus_tag="KB909_002942"
     CDS             <1..888
                     /locus_tag="KB909_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBB6838881.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          389 a          120 c          149 g          252 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt caacttttgg
      901 ggttcagttc
//
LOCUS       DADVXK010000254          857 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.267, whole genome shotgun sequence.
ACCESSION   DADVXK010000254 DADVXK010000000
VERSION     DADVXK010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.267"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..116
                     /locus_tag="KB909_002943"
     CDS             <1..116
                     /locus_tag="KB909_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBB6838882.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            244..795
                     /gene="raiA"
                     /locus_tag="KB909_002944"
     CDS             244..795
                     /gene="raiA"
                     /locus_tag="KB909_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBB6838883.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          306 a          151 c          177 g          223 t
ORIGIN      
        1 aaaaaatatt gattattgac gatgtctata caacaggaca gacgcttttt catgcagcag
       61 attgcttgca gaacgcacag ccgaaaatca tccgaaccat ttctttggca agatgaatca
      121 gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat ataatagaat
      181 taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa aggggtaatt
      241 tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc gattcgcgac
      301 tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc cgatgcaacg
      361 gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt aacgatccca
      421 ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc aagtatcgat
      481 ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat taatcgtaaa
      541 tcccgtgaaa cgggcatgaa tactgcagat gctgctgctt tattcaatga agaggacgaa
      601 aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt gaaaccaatg
      661 gatagtgaag aagcagtctt acaaatgaac atgctgggac ataacttctt tatttttgaa
      721 gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa atacggactg
      781 attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc agctactgac
      841 agctgccgca agttttt
//
LOCUS       DADVXK010000255          835 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.268, whole genome shotgun sequence.
ACCESSION   DADVXK010000255 DADVXK010000000
VERSION     DADVXK010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.268"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            59..415
                     /locus_tag="KB909_002945"
     CDS             59..415
                     /locus_tag="KB909_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6838884.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            405..671
                     /locus_tag="KB909_002946"
     CDS             405..671
                     /locus_tag="KB909_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838885.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
BASE COUNT          341 a          108 c          165 g          221 t
ORIGIN      
        1 aattcgaatt tttatgttat atactataat ataaaatcaa tatatgatat aattgggtat
       61 ggaaaaaata tcttttgaaa catttaaaag acctaatggt catgatgaat ttttagaatg
      121 gttggaaaca ttaccaaaaa aagatagtgc gaagctttta cgtacaatag aagaaacaga
      181 aaagaatggg atgctagtag ctcaacggtt gaaatgggtg aaaaaattag acactaattt
      241 gtacgaatta agaagtaagg taggatcaaa catccaaaga gctatctatt tccatgtggt
      301 caatggaagg tatgtcatta cccatggatt tactaaaaaa acggagaaaa caccaataag
      361 tgaacttaaa catgcaaaag aacttagaga ggagtggttc acaaatgatg attaaaaaat
      421 tgattgaaga aaagcaaaaa gacaaagatt ttgcagaagc atatgaccgt gaaggaagaa
      481 aactcgaaac tgcggttgct ctttatcatg cacgggagga agcaggccta actcaagcgg
      541 agcttgcaca aaaagcacat acaactcaat ctactattgc tcgaattgag agaggggata
      601 acgtatcttt cgataaactt gatgatatcg ctagggcatt aggcaaaaag ctggtagtag
      661 aatttgctta aaagcgagtt gaaaatatac ctgtaatagg ctcctaacta atcaattagt
      721 ttagtgggcc tttttgtact aaatagataa aagttgtcct atagtgtaaa agtcaataaa
      781 ttttatacaa aaattacttt aaagagacat aaagagaaag gtacaataaa tgaaa
//
LOCUS       DADVXK010000256          805 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.271, whole genome shotgun sequence.
ACCESSION   DADVXK010000256 DADVXK010000000
VERSION     DADVXK010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.271"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            374..>805
                     /locus_tag="KB909_002947"
     CDS             374..>805
                     /locus_tag="KB909_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6838886.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDD"
BASE COUNT          275 a          151 c          127 g          252 t
ORIGIN      
        1 taacaactat aacaaaaccg aatgcaaaac agaagttcta taagttataa tcatagttgt
       61 taggtgattc atctagtaaa aacaccagat ttcaaatttc acacaattta aactagatca
      121 atcatcaacc ttcttcaaat tgttagaacc ctttcccgag gagctgcagc ataagcaaaa
      181 aaacaaacag gaagccaaat ggctaagaca ttttttctat tagtctagtt gcttctcgtc
      241 gcaagtttaa gactttagaa agttatttct aatgatgttt gggttgtttt gatcaatgct
      301 tatgcacagc tccttaccta ttatttatct caacagatct aacaaattaa tggactattt
      361 aaggagtttt tttatgctta cgatctattc ttctcgcaca catagttacc atctgatggc
      421 aaactggctg aaagaccatc aaatgcctta cagagaacga attttcacac ctaaacagcc
      481 tttaacaagg aaagagatat tttatttatt gtcattaaca gaaaacggat ttgacgatct
      541 attagctaaa cgctcgattg attataaaaa tttgaaagac caaatcgacc aatgtacgac
      601 ctcagagctt gtcgatctga tcgtctcgca ttttactttg ttacaacgtc ccatcattac
      661 tgacggaaag aaattattag tcggattcaa tgaagatagc atgcgtcttt ttatccctgt
      721 acaatggcgc agaagtcaac tgaaatctgt ctataacgat tttacatggg taagcaatct
      781 agaaaattct acggatttag atgat
//
LOCUS       DADVXK010000257          803 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.272, whole genome shotgun sequence.
ACCESSION   DADVXK010000257 DADVXK010000000
VERSION     DADVXK010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.272"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..708)
                     /locus_tag="KB909_002948"
     CDS             complement(<1..708)
                     /locus_tag="KB909_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6838887.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHF"
BASE COUNT          287 a           88 c          142 g          286 t
ORIGIN      
        1 aaaatgtttt tttaagctgg ctggactgat aaaaaaaatt tgggctaatt gttcaagcaa
       61 aaaattttct gaaagatgtt cttctaaata tcgtatgatt ggatcaacta attcatctga
      121 ataaagaata tgcttttttt taggaatgac tttctcattt gaaggtattg tcaataaagc
      181 aagttcctgt tgataatgcc ttggtaagga agacaattga attttttgca gacaataagt
      241 aactaataag gaaagcaaat gaatgctcat ctgttggcat agtatgaaaa aagaattgat
      301 ttcctgatca taggaaatag ctggcttact atgttttaga taatcaattt tgaactgttc
      361 atttttcaga aaagtaatga tagatgttat ttcttgatct atagaaaaag attgtcccgt
      421 aatatgtgct aataattgct catcaaaata aaactggata atgataaaag tttgtgtttc
      481 cttttgagta gaaaagattt ggacttcttg ctgtttatca atgaataaaa gggaaggatt
      541 atctagttct atagatttat gtgcaaattc agcatataaa ttagcgcttt catttattag
      601 tagtcgaaaa tagggagcag cagataaatg aagatgggta tctatggaat aggttagtgt
      661 ttttttgaca agattggagg attggttgtt tgttaacaaa agaaccactt tcctttctct
      721 ttttatataa aaagctttct atttataatt aatgactatt ataacaaaaa tgaaaagcca
      781 aaacgacaag taaaatattt ttt
//
LOCUS       DADVXK010000258          789 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.274, whole genome shotgun sequence.
ACCESSION   DADVXK010000258 DADVXK010000000
VERSION     DADVXK010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.274"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
BASE COUNT          275 a           95 c          169 g          250 t
ORIGIN      
        1 tttgttgaaa gttgctttac tggcagcttt tttctaagta actttttgac aagctcaatg
       61 gcaacacaag cggaagaagt aatacaagaa ctaactgtta tgaataacag ctagataaaa
      121 tgggctatgt atgttatcca acaatttagt aatcactaga agcctagcga aagttcgctt
      181 gataagttat agatgagtat tgatttgtag tgtttccaaa tcaaaagggt acagagccac
      241 atgaaatatg ttgtcctctg cagcgtcagg atgggaatcc ataccatgga gattcggaga
      301 tctgtgaggg aatacttacg tggttaatat gtcagttgtg ttggacgtag taatggtcat
      361 agtgggtaga ttgactgaat tcttatatga gaaaatgaaa ccaacaagaa gatagggtta
      421 tttatacaga attggggatc ttttctggaa aagtaatcgg ataatgcgag attcgtacgg
      481 tcttttttaa atttctctaa aaaaaacggc atcgaatggg ttgggtgatt gataagcaat
      541 gaatcataga ctgatataga ataaaaaatg attctattta tctttttaca tctatcgttt
      601 tttcaagtag ccgcaaatta tatcagcatt caacaatttt tgtatacaag ttctagtaaa
      661 aggatctgaa gaaaaagttg gttgttgtga agataaaaaa agaatcaggt tttactgagt
      721 ttttcttcaa aatttgtgtt attaggttag gacaaagata agaagaagta tgaagattta
      781 aaaaaggaa
//
LOCUS       DADVXK010000259          756 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.275, whole genome shotgun sequence.
ACCESSION   DADVXK010000259 DADVXK010000000
VERSION     DADVXK010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.275"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(18..>756)
                     /locus_tag="KB909_002949"
     CDS             complement(18..>756)
                     /locus_tag="KB909_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBB6838888.1"
                     /translation="VVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVY
                     FSFGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFT
                     IWKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQV
                     LVSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVL
                     FNKRDVISIVFWYYLGSISYLYLKKEN"
BASE COUNT          287 a          135 c           88 g          246 t
ORIGIN      
        1 tgaaagctgt cttcatatta attctccttt tttaaataca agtaagaaat gcttcccaaa
       61 taataccaga aaacaattga aatgacatcg cgcttattga aaagtacatg agcctccacc
      121 atttcatcta taaaaataga tagtataaaa attaaaacaa taccaagaaa cgcataattc
      181 actttacttc taaaaaatgt tttgagtaaa ctaaagatat ttaacacata gaaagcatag
      241 atacatataa aagcaattat accacttgat acaagtactt gaagaaatcc attatgcatg
      301 tttccatgtg ctctttttag ttcattcaca tctgtagtat caagatctac ttttttcaaa
      361 aattttgcat cgctattccc atagaaatcg gtctctccat aaccaaataa caaagttggt
      421 cttataactt taagcgcagc tttccaaatc gtaaaacgac cagctgaaat ttcggagtta
      481 tcactagaat gctgtaatat tacttctttt tctggaagtg gagttttatc tgattcattt
      541 gactctataa cttctacttt tctatcaatc gatacaggaa ttgttgctaa aaaatcctta
      601 gcataattag taccaaaaga aaaatatacc aatagaacta ataatatgct taccatccat
      661 ttgattttta caggtagtac ttctctaatg ctctttctaa attttgaatt ggcaaacaac
      721 aaaagaaata atactaaaaa agaacaaatt actacc
//
LOCUS       DADVXK010000260          730 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.277, whole genome shotgun sequence.
ACCESSION   DADVXK010000260 DADVXK010000000
VERSION     DADVXK010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.277"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(50..634)
                     /locus_tag="KB909_002950"
     CDS             complement(50..634)
                     /locus_tag="KB909_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6838889.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          229 a          161 c          106 g          234 t
ORIGIN      
        1 tcacttttct agataaatgg caaaaatttt cagcattaaa tgacaaaaac taatgagaat
       61 ttgtctttcc atttttctcc tccatttttg ccaaataacg ataaatggtg gttcttgaga
      121 cgttccaccg ttccgcaata gtcttaatag gtgtaccgct atccactaaa gtcttcagta
      181 attccaaatc ttgttcagac aatttttcag gacgaccacc aaaccgtcct cttgcacgag
      241 cagctgctcg tcctgctgcg gatcgttcca ggatcaaatt acgctcaaat tctgcaaatg
      301 ccgcaaacaa atgaaacatg agctgtcctg tagaacttga tttgtccatc gtaatatttt
      361 cttgaatact atgaaaactc acaccacgct cattcagtcg attgacgatt gaaatcaaat
      421 cttccatatt tctacctaaa cgatctaagc gccaaacgac aagtgtatcg ccagagcgaa
      481 caaaatcaat ggccatttct aatcctggtc gattactttt tgccccactc atatgatcag
      541 taaaaatttt ttcacaacca aatttattta ggctgtcttc ttgtaaatcc aaattttgta
      601 aaccagtaga tacccgggcg tatcctattt tcaaaaaaat cactccttca ttaattttat
      661 tgtaacataa ctttatccat atagtttaac tgaacataga tattgttatg ggtttatgaa
      721 catgaaatga
//
LOCUS       DADVXK010000261          725 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.278, whole genome shotgun sequence.
ACCESSION   DADVXK010000261 DADVXK010000000
VERSION     DADVXK010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.278"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            8..430
                     /locus_tag="KB909_002951"
     CDS             8..430
                     /locus_tag="KB909_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838890.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            440..643
                     /locus_tag="KB909_002952"
     CDS             440..643
                     /locus_tag="KB909_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838891.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
BASE COUNT          287 a          107 c          115 g          216 t
ORIGIN      
        1 atagacaatg aaaaataagt ttattttatc tttaggtatt ttaactattg gaattagtgt
       61 aactggaact acaattccta catttgctga tagtacaaat gaaccaacta ctgtagtaga
      121 taataaccaa gaattaactc ctttagatag gaacggaata gccattggta acccaactaa
      181 cgacttaact gttactgaaa attatttaat agtttctcca ttacttgctc gagcagcttc
      241 taaaacgata cgagtgacag gaacgatgat ttttgataaa gttggttggc cttctagacc
      301 tcctcaatca cggaattgga aagaaaaaag aaatggttat tggtactatg gaaaattgta
      361 tttacaaagt tataaatcag ctggaaacaa ttggattgcg acttattcag gaaccttaac
      421 tagaaagtag ggatttttta tgccagaatt tgtgaacaca ccaaattttt atcaagatag
      481 cgatattcta agtaaaatta atttaccgaa agaagaatca gctttacaag ttcagcgaac
      541 tttacaggag acacaaaaaa ttcaaaaatc aatttctaat ctagaagatt ctgaagaaaa
      601 aagaaaaaaa agagaccaaa aaacatatca aaaagaaaaa taatgatttt aaaaaaagag
      661 tgtctagtcg acattctttt tttctaattg aaagtgttca taaaatcacc catttctgga
      721 cactt
//
LOCUS       DADVXK010000262          645 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.281, whole genome shotgun sequence.
ACCESSION   DADVXK010000262 DADVXK010000000
VERSION     DADVXK010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.281"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(14..400)
                     /locus_tag="KB909_002953"
     CDS             complement(14..400)
                     /locus_tag="KB909_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838892.1"
                     /translation="MKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRFEVLKIQKNE
                     LLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTDVVMITDIYV
                     EDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          201 a          122 c           79 g          243 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg ttcctttatt tttattaaca agttttatca
       61 caggcttcat atatttgatt atatcttcat cttctacata gatatctgtt atcattacga
      121 catctgtact atttcgattg agtactttca cttgatctcc agcattgatt ttccctctaa
      181 atcttttagg aatgaaccaa ctatacatat gattagcatc accaaaatgt gcttttatcg
      241 cattctcagg atataactta ttcaatagtt cattcttttg aattttcaaa acttcaaatc
      301 tatacttatc atcttctgct aatctaaata aatcttctaa acgcatgttt tctaactgta
      361 agttttgaaa atcttccggt ataaattttc tatatttcat taataatgaa cgcccagccc
      421 gatttattag aatctggcca ttttggtcat ctctataaag aattccgtaa cccatcaacg
      481 ccaatagcac acgtgacgtt ttgttacttg taatattcat atttccttga ttacctgagg
      541 caatgaaaga cttatctact tgaattaggg tgaaattctc attcaaatat ggtagtaaaa
      601 ttaatatatg tgaaaatcga atcttgagat agctattccc cttga
//
LOCUS       DADVXK010000263          625 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.282, whole genome shotgun sequence.
ACCESSION   DADVXK010000263 DADVXK010000000
VERSION     DADVXK010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.282"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            1..625
                     /locus_tag="KB909_002954"
                     /pseudo
     CDS             1..625
                     /locus_tag="KB909_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DADVXK010000264          615 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.283, whole genome shotgun sequence.
ACCESSION   DADVXK010000264 DADVXK010000000
VERSION     DADVXK010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.283"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>615
                     /locus_tag="KB909_002955"
     CDS             <1..>615
                     /locus_tag="KB909_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838893.1"
                     /translation="KFANSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLL
                     VNTVVELAKWAKSNETYSQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENS
                     QWIKELKREDFIETLRILKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEK
                     RIDNIINYINSLSEPLKCRGLDFIGTLGWTETYYEKIYKEIIEQ"
BASE COUNT          257 a           63 c          111 g          184 t
ORIGIN      
        1 ctaaatttgc aaactcattc tggtttttaa aaaatattaa taaaacagtg gaaaagaatg
       61 gagtttataa aggtgatttt cattttcaaa atgctgagac tattgaacga gaacatcatt
      121 atttcgattt attagtgaat acagtggtag aattagcgaa atgggcaaag tcaaacgaaa
      181 cttatagtca agtacttaaa agaattatga gtcaagaaac ttcatttatc tatgagttaa
      241 gcaagtcaaa tttgaaatat acttataatg aagatgaact tgaaatttta gataatccag
      301 aaaattcaca atggattaaa gagttgaaga gagaagactt tattgagaca ctaagaattc
      361 taaaatcgtt atttgatttg aaattagcca aagctaccat catgggaatt gaaagagatt
      421 catattattg ggaggaaatt ggactatatg ctccccagat tgaaggtgaa gataaagaga
      481 aaaggataga caacattatt aactatatta atagtttaag tgaaccttta aaatgtagag
      541 gacttgattt tataggaaca ttaggatgga cagaaacata ctatgagaaa atatataaag
      601 aaataattga acaat
//
LOCUS       DADVXK010000265          603 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.285, whole genome shotgun sequence.
ACCESSION   DADVXK010000265 DADVXK010000000
VERSION     DADVXK010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.285"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>603
                     /locus_tag="KB909_002956"
     CDS             <1..>603
                     /locus_tag="KB909_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838894.1"
                     /translation="ENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHD"
BASE COUNT          236 a           70 c          117 g          180 t
ORIGIN      
        1 ctgaaaacaa taacgcatta aggaaatttg acatttttaa tagttcgatt gaagttccct
       61 atatcgaaaa ggtaagtgca gatgtattaa aagttgaaga aattacttat gaaaatattc
      121 taaaagacat aaattttgat gtcaaagttg gagatgttat tggtttggta gggaaaaacg
      181 gtgtggggaa aacaacctta ctaagaatac tcatgaagat tattcgccct accaaaggaa
      241 agataatcga aaataaaaaa aatttgtcat cgccgttttt agtaatgcaa gaaatggatt
      301 accaattttt cacagaatca gtgaggagcg agttagccct ggggaatgaa atagttagta
      361 aagatcagca agaaaaaatt ttaaaaaaaa tggaacttta taaaatgaaa gatcaattac
      421 cgtttgattt atccggtgga gaaaaacaaa gattattggt ttctatagct tcattgtcaa
      481 aaactaattt atttctattt gatgaaccta caagtgggtt ggattatatt aatatggaaa
      541 ggattgctga ccttattaaa gacttaaaag aaaagggtgc agtagttata gctactcatg
      601 atc
//
LOCUS       DADVXK010000266          556 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.289, whole genome shotgun sequence.
ACCESSION   DADVXK010000266 DADVXK010000000
VERSION     DADVXK010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.289"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>556
                     /locus_tag="KB909_002957"
     CDS             <1..>556
                     /locus_tag="KB909_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6838895.1"
                     /translation="SNIYHNCVPDKIKNRRNTDKLKQRDTVIIACVIWGIINGYTSQR
                     ATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPS
                     PLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDV
                     KVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          193 a          101 c           97 g          165 t
ORIGIN      
        1 tctaacatat accacaattg tgtaccagat aagattaaaa accgaagaaa tactgataaa
       61 ctgaagcaac gcgatacagt gattattgct tgtgttatat ggggcataat taatggctat
      121 actagccaaa gagccacgta tagagcggtt tgttccgtct tatttcctaa tggtgacttt
      181 cctagtagga gtcgattcac tcgcttaagt tcaaacttag cttacactat caagattatt
      241 cgatactttt tcatcaagaa gctcaccaaa ggtgaactag tcggaattat agatagtttt
      301 cctagtccat tatgtaaacc agttagaaat agacaagcaa aactattgaa tcaaatagcc
      361 aaagttggct ataactcaac aaaaaaatct tatttttatg gtcttaaaat tcatatgatc
      421 gttactaaga ctggctttcc gattacttac tcaatcacga atccaggtgt ccatgacgtg
      481 aaagtgttag agactttatc ggaagaagcg aatcttccca atatcctagg ggacaaagga
      541 tatattagcc ataaaa
//
LOCUS       DADVXK010000267          536 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.290, whole genome shotgun sequence.
ACCESSION   DADVXK010000267 DADVXK010000000
VERSION     DADVXK010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.290"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..489
                     /locus_tag="KB909_002958"
     CDS             <1..489
                     /locus_tag="KB909_002958"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6838896.1"
                     /translation="FDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKT
                     AVFNSNQSVLLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENS
                     HEIAEVIMVLSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQF
                     CK"
BASE COUNT          201 a           71 c           95 g          169 t
ORIGIN      
        1 ttcgattcaa aggaagatat tttaaaagca atttttcaaa gaattggaaa tgaaaatgca
       61 gtaatatttg ctaaaattag agataacgat agtttaaacg gtttagaaaa gttaagagaa
      121 atatttaaga cagcggtatt caattctaac caaagcgttt tattgacagt ttctcctcaa
      181 ctattaaaca atcctcgttt tcttgctatg caaatagaac aaatgtatga aattgtagta
      241 cctgaatttg ttgaacccgt tttagaacaa ggtatcaagg ataagtcttt ggagattgaa
      301 aattcacatg aaattgcaga agttatcatg gtattaagta atgtatggct caacccatta
      361 gttgaaatga cggataaaga gggtatggaa aaacgttgca atacattcaa tgccctttta
      421 aatggaatag gcatagacac attattagac gaagaaacaa tttctgcatt tatacagttt
      481 tgtaaataac tgtatttgtt atccctatac gatagactgc tctataaaag agcagt
//
LOCUS       DADVXK010000268          519 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.292, whole genome shotgun sequence.
ACCESSION   DADVXK010000268 DADVXK010000000
VERSION     DADVXK010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.292"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>519
                     /locus_tag="KB909_002959"
     CDS             <1..>519
                     /locus_tag="KB909_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6838897.1"
                     /translation="FSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNLYSEEKNCV
                     LDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHEGMANTNLE
                     SAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYEQRINMGKM
                     GRNYMIKKFNKK"
BASE COUNT          200 a           54 c          107 g          158 t
ORIGIN      
        1 actttagtta tttagaatat cctaaagatg agcaagttca ttttttattt attggaagaa
       61 ttatgaaaga gaaaggtgta gatgaacttt ttgaagcaat gaaaaactta tatagtgaag
      121 agaaaaattg tgtacttgat gtccttgggt attttgaaga agattacggc ataaaaattg
      181 aaaaatacga aaaagaggga tggttaaaat atcatggata tcaatctgat attcgtccct
      241 ttgtagaaag agcacattgc tttgttttgc ctagttggca cgaaggaatg gcaaatacta
      301 accttgaatc agcagcatca gggagaccaa ttattacaag tgatatccca gggtgtaaag
      361 aagcagttat tgaatcgaag tctggttatt tatgtgaaag aaaaaatagt tgtagtctct
      421 ataattcgat gaataaattt ctaaaattat catatgagca gcgcattaac atgggaaaaa
      481 tggggagaaa ttatatgatt aaaaaattta ataagaaga
//
LOCUS       DADVXK010000269          517 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.293, whole genome shotgun sequence.
ACCESSION   DADVXK010000269 DADVXK010000000
VERSION     DADVXK010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.293"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(271..>517)
                     /locus_tag="KB909_002960"
     CDS             complement(271..>517)
                     /locus_tag="KB909_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838898.1"
                     /translation="TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKV
                     GKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
BASE COUNT          187 a           93 c           66 g          171 t
ORIGIN      
        1 cataaaaaaa cagtactgtc tagtagtata aaatatacaa atttcttaaa aattttttca
       61 ctaaaatcac tacctgaaac agtctaaaac acttatatat caacgtttaa tgaaactatc
      121 tccgtttcat ttcagataca aataaatata gtcgggctcc aaatccgaaa aaaaataccc
      181 ccagtagctt atcctaagct actggagatg tataagtacg gtcatataac aacggggtag
      241 ggtaaataaa tgaaaaagat ggaagaatca ttattcaata acttttttaa atacttcgtt
      301 gtaatcagtt acctgtccgt tcttaaatac cacagaataa tcttttttcc cattttcaag
      361 taaccgaagt ggaatatctt taccaacttt ctctgtcact gcattactga tacctgttag
      421 attagctaat aaatctgata aagattgagc atctgtagaa atctctgtat cagtatttat
      481 cgtgattcct ttatcttcat ttacaagttt ccaagta
//
LOCUS       DADVXK010000270          516 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.294, whole genome shotgun sequence.
ACCESSION   DADVXK010000270 DADVXK010000000
VERSION     DADVXK010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.294"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..155
                     /locus_tag="KB909_002961"
     CDS             <1..155
                     /locus_tag="KB909_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBB6838899.1"
                     /translation="KDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDAI
                     SYGVRK"
     gene            174..>516
                     /locus_tag="KB909_002962"
     CDS             174..>516
                     /locus_tag="KB909_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6838900.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFK"
BASE COUNT          229 a           40 c           92 g          155 t
ORIGIN      
        1 ataaggataa gtgtattaat tgtggaaaat gtaaaaaagt ttgccaaatg aataaagatt
       61 cagttgagaa ttgcaatcat ctggagtgta tcagatgtgg acgatgtaaa aatgcttgtc
      121 cagtggatgc aattagttat ggagtaagaa aatagagagg agtagttagg aaagtgataa
      181 aaaatgctat agcatatatt acaagaaaga aaaatagaac tttaataatt tttatcatat
      241 taactatagt tctttcttgc ttgtattctt gtttaacaat aatgaaatca agcaatgaaa
      301 tagaaaaggc tttatatgaa agttctaatt cttcaatatc aataacaaaa aaagatggta
      361 aatattttaa tgttaatcaa tttaaagata ttgaaaaatt aaaagaaatt gaagaaaaaa
      421 taattcaata tgatggatta gcaaaactaa aagatgctaa agtagttagc ggagaacaaa
      481 gaataaatag agaagattta tctgacgaat ttaaga
//
LOCUS       DADVXK010000271          464 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.301, whole genome shotgun sequence.
ACCESSION   DADVXK010000271 DADVXK010000000
VERSION     DADVXK010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.301"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>464
                     /locus_tag="KB909_002963"
     CDS             <1..>464
                     /locus_tag="KB909_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838901.1"
                     /translation="LVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSG
                     NSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVT
                     MSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          168 a           85 c           77 g          134 t
ORIGIN      
        1 ctagtcacta aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac
       61 acactcctac ggactgaatt aacggctttt ttagattacg aaaaatatga tcgcactggt
      121 tttaattcag gtaattcgag aaacggttct tactttcgat caatcaaaac cgaatatggt
      181 gaattaacat tggaaatacc tagagatcgt aatggtgagt ttaaacaaca aactttacca
      241 gcctacaaaa gaacaaacga tacattggaa accactatta tccatttatt cgaaaaaggt
      301 gttacgatgt ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca
      361 caaaccatgt ccaacatgac taaagttctg actgaagaag taaatgcctt taaatccaga
      421 gccttaaatg ataagtatgt cgctattttt atggacgcta ctta
//
LOCUS       DADVXK010000272          462 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.302, whole genome shotgun sequence.
ACCESSION   DADVXK010000272 DADVXK010000000
VERSION     DADVXK010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.302"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..430)
                     /locus_tag="KB909_002964"
     CDS             complement(<1..430)
                     /locus_tag="KB909_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6838902.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DADVXK010000273          451 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.303, whole genome shotgun sequence.
ACCESSION   DADVXK010000273 DADVXK010000000
VERSION     DADVXK010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.303"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(36..272)
                     /locus_tag="KB909_002965"
                     /pseudo
     CDS             complement(36..272)
                     /locus_tag="KB909_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          147 a           76 c           77 g          151 t
ORIGIN      
        1 atagaaggac tgaccttctg tctcagattt ttttgttatt tcacttgaat caattgattg
       61 atcaaaaaaa tcctgatttt catgttctca aatgatttaa atccataaga taatcgtttc
      121 agtgtcttga tatggggaat cttggcctct attttgccat tagaatacgg gtaaatcata
      181 gcattgtaaa taccttcttc atacgttaaa aggttttgaa gtttcgtgcg aagttgtgca
      241 tcaagtgttt caggaagatt ttttaataac gccgtttgta taattaagcg agacaaataa
      301 aaaagccatt tatgttacac tccaattgta atacccgcta aagcatacaa ggagagtgaa
      361 cataaatgac ttatacccat cttacaccaa acgagcttgt aatgatagaa gcatattttc
      421 atcaagaaac tccggttgct atcgttgcga a
//
LOCUS       DADVXK010000274          434 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.304, whole genome shotgun sequence.
ACCESSION   DADVXK010000274 DADVXK010000000
VERSION     DADVXK010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.304"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..>434)
                     /gene="wzy"
                     /locus_tag="KB909_002966"
     CDS             complement(<1..>434)
                     /gene="wzy"
                     /locus_tag="KB909_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBB6838903.1"
                     /translation="DSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTYLTSLLG
                     SISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVYIFIIGI
                     VIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYL"
BASE COUNT          168 a           82 c           59 g          125 t
ORIGIN      
        1 attaaatatg aagcagctct aggaaaaccc attataatat ttgctgtagt tatagccaaa
       61 aacatcttca taggatgatt ttcaatatct tggttgtcta tactattaga aaggatttta
      121 ccgatgacta taccaataat aaaaatatag actatacccc caatgtatcc accattgaca
      181 taggcttctg caatcattga gaatccagtc ccccaagtga ttcctaaata atcctgagaa
      241 aaccaatcag ctaataaaac aaactttatt ccaaacattg atagcattct tgttgatata
      301 gagcctaaga gtgaggtcaa ataagtatta gcaaagggat atattccatt accacttatt
      361 aggaaaaaag ttataatact catagtcccc cccatttcaa aaaaagaatc aactaaagga
      421 gaatcatctg aatc
//
LOCUS       DADVXK010000275          422 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.306, whole genome shotgun sequence.
ACCESSION   DADVXK010000275 DADVXK010000000
VERSION     DADVXK010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.306"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>422
                     /locus_tag="KB909_002967"
     CDS             <1..>422
                     /locus_tag="KB909_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838904.1"
                     /translation="TVLLLITLTVSSKKNFNQKIISQPGHIVVNKETVEAYTTKGMDY
                     FLYDYSPIASLENKEHIIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYA
                     YLGTNVEINHQPVKEQVNANGLVQISGVKGVADIKVST"
BASE COUNT          162 a           60 c           78 g          122 t
ORIGIN      
        1 gactgttttg ttattaatca ctttaactgt ttctagtaaa aaaaatttca atcaaaaaat
       61 aatttctcag ccgggacata ttgttgtaaa caaagaaaca gtagaggcgt ataccactaa
      121 aggaatggat tattttttat atgattattc tcctatcgct tcattggaga ataaggagca
      181 tataataaaa cacgaagcaa agattggcag tcaatgggta aaccttcctt ataaaacaac
      241 tggtagttct atcatatata gagtaactaa tgagaagagc caagtaatca cacttcctgt
      301 atatgcttat ttaggaacga atgtagaaat aaatcatcaa cctgtaaagg agcaggtgaa
      361 tgctaatgga ttggtacaaa taagcggagt caaaggagtt gctgatatta aagtaagcac
      421 aa
//
LOCUS       DADVXK010000276          415 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.307, whole genome shotgun sequence.
ACCESSION   DADVXK010000276 DADVXK010000000
VERSION     DADVXK010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.307"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..339)
                     /locus_tag="KB909_002968"
     CDS             complement(<1..339)
                     /locus_tag="KB909_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6838905.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DADVXK010000277          414 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.308, whole genome shotgun sequence.
ACCESSION   DADVXK010000277 DADVXK010000000
VERSION     DADVXK010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.308"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(109..>414)
                     /locus_tag="KB909_002969"
     CDS             complement(109..>414)
                     /locus_tag="KB909_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6838906.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          116 a           96 c           82 g          120 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggt
//
LOCUS       DADVXK010000278          375 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.denovo.313, whole genome shotgun sequence.
ACCESSION   DADVXK010000278 DADVXK010000000
VERSION     DADVXK010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.denovo.313"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..132)
                     /locus_tag="KB909_002970"
     CDS             complement(<1..132)
                     /locus_tag="KB909_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6838907.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DADVXK010000279        16853 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.056, whole genome shotgun sequence.
ACCESSION   DADVXK010000279 DADVXK010000000
VERSION     DADVXK010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.056"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(134..577)
                     /locus_tag="KB909_002971"
     CDS             complement(134..577)
                     /locus_tag="KB909_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6838908.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="KB909_002972"
     CDS             complement(795..2135)
                     /locus_tag="KB909_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838909.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="KB909_002973"
     CDS             2404..3300
                     /locus_tag="KB909_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6838910.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="KB909_002974"
     CDS             complement(3450..4391)
                     /locus_tag="KB909_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6838911.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="KB909_002975"
     CDS             4517..5638
                     /locus_tag="KB909_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6838912.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB909_002976"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB909_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6838913.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="KB909_002977"
     CDS             7426..7992
                     /locus_tag="KB909_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6838914.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="KB909_002978"
     CDS             8203..9264
                     /locus_tag="KB909_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6838915.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="KB909_002979"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="KB909_002979"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6838916.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="KB909_002980"
     CDS             10177..12159
                     /locus_tag="KB909_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6838917.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="KB909_002981"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="KB909_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6838918.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="KB909_002982"
     CDS             12881..14305
                     /locus_tag="KB909_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6838919.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="KB909_002983"
     CDS             complement(14486..15259)
                     /locus_tag="KB909_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6838920.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="KB909_002984"
     CDS             complement(15256..16161)
                     /locus_tag="KB909_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6838921.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="KB909_002985"
     CDS             complement(16315..16635)
                     /locus_tag="KB909_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6838922.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         5432 a         3083 c         3468 g         4870 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaa
//
LOCUS       DADVXK010000280         7905 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.115, whole genome shotgun sequence.
ACCESSION   DADVXK010000280 DADVXK010000000
VERSION     DADVXK010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.115"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            128..1564
                     /locus_tag="KB909_002986"
     CDS             128..1564
                     /locus_tag="KB909_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6838923.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4185
                     /locus_tag="KB909_002987"
     CDS             1753..4185
                     /locus_tag="KB909_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6838924.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            4415..5482
                     /gene="rlmN"
                     /locus_tag="KB909_002988"
     CDS             4415..5482
                     /gene="rlmN"
                     /locus_tag="KB909_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6838925.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5675..6778)
                     /locus_tag="KB909_002989"
     CDS             complement(5675..6778)
                     /locus_tag="KB909_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6838926.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7330..7878
                     /gene="aac(6')"
                     /locus_tag="KB909_002990"
     CDS             7330..7878
                     /gene="aac(6')"
                     /locus_tag="KB909_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6838927.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2640 a         1353 c         1718 g         2194 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaagttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaata tgagaagaaa aaagcggtga gccagcaaag ggaaaatact
     2521 gctgatgaat ggcaggaacc agaaaataca gagccggagc agctaagttt tgttccaatc
     2581 gacagttttc aagaaaatat ccatcctgcg aatctagaga aaccagtacc agatacacca
     2641 aaacagacca atacagcaga aggtttttca gatgagttgc cagaggatga cggtacctca
     2701 ttagaatttg agattgaagc agaacaggaa aatcaagact atgaattacc gacagttgat
     2761 ttgcttgatt ctataccaac tgtggatcaa agtgatgagt ataaaaaaat tgaaaaaaat
     2821 atcggcgtat tagaacaaac tttccaaagt ttcggtgtcg atgccaaggt cgtcaaagcc
     2881 agcttaggac catccgtcac aaaattcgaa gtccagccgg ctgtaggggt aaaagtaagt
     2941 aaaattgtga acttaacaga tgatatcgcg cttgctttag cggcgaaaga tgtccggatg
     3001 gaagcaccga ttccaggtaa atcactgatt ggtattgaag taccaaatgg aaagatcagt
     3061 atggtttcct ttagagaaat catcgaagca caaccaaacc acccagataa attactagaa
     3121 gtacctttag gacgtgatgt ttctggacgg gtacaaacgg ctgatctttc gaagatgcct
     3181 cacttactcg tggctggttc gactggtagt gggaagtcag tagcaattaa tgggattatc
     3241 acaagtatat taatgcgtgc taagccccat gaagtaaaac tgatgatgat cgatccgaaa
     3301 atggttgaat tgaatatgta caacggcata cctcatctgt tgacgccggt cgtgacgaac
     3361 cctagaaaag cagcgcaagc cttacaaaaa gtagtacaag aaatggaaga acgatatgaa
     3421 aaattcgcgg caaccggagt aagaaatatt tctggttaca atgaatttgt tcaacagaaa
     3481 aacttggaaa acggaacgaa acatccaacc ttaccattca tcgtagtgat cgtagatgaa
     3541 ttagctgatt tgatgatggt agccagcaat gaagttgaag atgcgattat tcgtttagcg
     3601 caaatggctc gggcagcggg gattcatatg atcctagcta ctcaacgtcc aagtgtggat
     3661 gttatcacag gaatcatcaa agcaaatgta ccttccagaa tggcatttgc ggtatcaagc
     3721 ggtacagatt ctcggacgat cattgattct aatggggcag aaaagctctt agggcgagga
     3781 gatatgctat tcttgccaat gggtgagaat aaaccgatcc gtgtgcaagg agcattcatt
     3841 tctgaccacg aagtagaacg ggtcgttcaa tttgttacag atcagcaaga agctcattat
     3901 gaagagaaaa tgatgccgac agatgaagtt gaaacgacag gtgctccaga acagccacaa
     3961 gatgagctgt ttgaagaagc aaaagcactt gtcgttgaaa tgcaaacggc aagtatttcc
     4021 cttctccaaa gaagatttcg gatcggttac aaccgagcag cacgtttagt agatgaactg
     4081 gaagctcatg gagttgttgg cccgtcagaa ggaagcaagc ctcggaaagt attcattgag
     4141 caggaagaaa catcagaaac gttgccggac gataatgaca tgtaaaactt gtgtgatgaa
     4201 gggttgaaaa acgaataacc aataaaaaga caaggcatga tgataccaaa agaaaaaatg
     4261 gtttttttcc atcttttcta atacggtatg atgtcttgtc tttttagttt ttgtgagatt
     4321 aaagttctat tcgatttatt tgtgaagtat tgcattaagg aaatgaatca tgtatagtat
     4381 gtagcgaaac tttgagaaaa agagggaaaa tactttggaa aaacagtcca tttatggctt
     4441 gacgaatgaa gaattaatca attggtttat agaaaacggc gagaaaaaat tccgagctgc
     4501 ccaagtttgg gaatggttgt atcaaaaacg tgtaagtaat ttcacagaaa tgacgaatct
     4561 atcgaaacaa ttgatcgaaa aattatcgga gcattttatc atcaatcctc taaaacagat
     4621 ggtcgtccaa gaagcttcgg atggtacagt aaaatatttg tttgaactcc ctgataaaaa
     4681 catgattgag actgtactga tgagacaaga atatggcttg tcagtttgtg tgacgacaca
     4741 agtaggatgt aatatcggct gtacgttttg tgcaagcggg ctgctcaaaa agaaccgtga
     4801 tctgactgct ggagaaattg ttgcacagat catgatggtc caacattatt ttgatgagcg
     4861 caatcttggc gaacgcgttt cacatgtcgt tgtaatgggg atcggtgagc catttgataa
     4921 ttacgacaat gtaatggact ttttgcatat catcaatgat gccaaaggat tggcaattgg
     4981 tgctcggcac attacagttt ccactagtgg attagcacac aaaatcaagg aattcgctaa
     5041 taacggcttg caagtcaatc tggctatttc cttgcacgcg ccgaataatg aggtgcgaac
     5101 atcgatcatg cggatcaacc gaagtttccc aattgagaaa ttgatggaag ctgtggatga
     5161 gtatttagag aaaacaaacc gtcgaatcac gtttgaatat atcatgttga atcaagtaaa
     5221 tgatagacca gagcatgcgc aacaattagc agatctatta aaagataaga aaaaattagc
     5281 atatgtcaac ttgattccat ataatccagt cagtgaacat gatcaatatt ctcgcagtcc
     5341 aaaagctgat gtattgagat tttatgatgt attgaagaaa aacggcgtaa actgtgtgat
     5401 acgtaaagaa catggtacag atattgatgc agcttgcgga caattgcgaa gcaagcaaat
     5461 gaaaaaaaca gttgccaaat aatcgtatcc tactcgtttt ttcaattacc ataaaaggag
     5521 cagttttctt aattaaggaa ctgttcaact taaataagag aaaagattct atagcgaaag
     5581 ctataaagct ttttttgaca agaaaaaccc tcatcaagca aagaaatgtc ctcaatttga
     5641 tgacagcctg cttgatgggg gttttagcaa ttatttaact gattttctta tatccttgct
     5701 ggctttcttg tgtagcatga taagtttcta cgtcaagaat ggcctgttta aatttttctc
     5761 gggtgatttc ataaggcaca tgtttaatat catttgttgc catggcttta tctaagattg
     5821 cttctaaatc ggtcgtgaca ttgagattca tgtcggttaa cgatactgga agttggttct
     5881 ttttcataaa cacatagatt ttatcaaaca aatcgaactg ctgatccatc atcaataagg
     5941 tcagtacacc ataactgaca gatgctccgt gaaggtatcc ctccattttt tctagaacag
     6001 tcgtaccgta atagaatgag tgtgccatag cagaattata gttattgtta actaaaacag
     6061 aaaccaatcc ggtagtaaca atgatatccg aaacgacttg ttcaattgca tatgagggac
     6121 gatcgtcggc actatctttc aatgcttgcg taccataagt caagagacga tcaatgcaca
     6181 tttttccgat ttggattcct aatctatccg tgtagcctag atcatcgcca cgagcagaaa
     6241 aagtagattc gacttctttg gataaagcat cgccaatacc tgcccataag tatttatcag
     6301 gtgcttcggc aataattgct gtatcaatga aggtgtgtac aggtggtttt gaaggaaaga
     6361 agagtccgtc cattacgcct tcttcgttat agatgacaca taccgcagtg acgggcgaac
     6421 agttcgaacc aatagtggga aaggtgaaga ctggtttagc tagtttttca ccaatgactt
     6481 ttacagtatc gcaagcacgg ccaccaccga ctgcaaacag gacgtctgct ttttggacac
     6541 tttcatgctg gatcaactgt tcaatatttc cataagttga attacccccg taccagagac
     6601 tggcgacaac ctctatttcc tgtgtcaaag ctacttttat tttgttttct gcctttgaaa
     6661 gtgcagtctt ccctccaatc agcactactt ttgtcccata ttctttgacg attccatttg
     6721 ctttttcata cgcatctgtt ccaatggtat aatttggtaa gaaaacactt tgactcatat
     6781 tcatttcctt ctttcttcgt tgaaacgggt taaaatttta aagagtgatc gatctgactg
     6841 cggctgtaga tggagtagag gtgaacctaa gacaggataa gtgatgaata aggtggcatg
     6901 aacaccttga aatcatcaat aagtatccta aaaacgaaca agtacaaaaa cattgaaaac
     6961 gacaataatg aatttttgtt cctcttagta tttctaccga ttccctttgc ttttttgtaa
     7021 ttatctaaaa attctaaaaa ttaagattat tatatgaaaa caggttttat ttgtcaattc
     7081 ataattggtt ttttttaaag caaaagataa tctatatcat gatgaacaaa cagagttttt
     7141 tcctccaatt gatggctttc ctgatctttc ctattttgaa taaagtgttt ctgtataatt
     7201 ttttatttta taagtaagat aaataatgaa agaatagaga tactgattgg tagctaaaga
     7261 tttttgagcg agaacatttc gttttttcaa aaggactgtt agaataagca agaacaaggg
     7321 ggaagacgta tgataatcag tgaatttgac cgtaataatc cagtattgaa agatcagctt
     7381 tctgatttac tgagactgac ttggccggaa gaatatggag acagctcggc agaagaagta
     7441 gaagaaatga tgaatccaga acgaatcgcg gtagcagcgg tagaccaaga tgagttagta
     7501 ggatttattg gtgcaatccc tcaatacggt atcacaggtt gggaattgca tccattagtt
     7561 gtagaaagct cccgacgaaa gaaccaaata ggtactcgat tagtcaatta cttagaaaaa
     7621 gaagtagctt ccagaggagg aatcacgatt tatttaggta cggatgattt agaccatgga
     7681 acaacgttaa gtcaaacgga cctgtatgag catacatttg ataaagtggc ttccatccag
     7741 aaccttcgtg aacatccgta tgaattctat gaaaaattag gttataaaat cgtaggtgtc
     7801 ttaccaaatg caaatggctg ggacaaaccg gatatttgga tggcaaaaac gattattcct
     7861 cgaccaaatt ctcaataata aaaagaggtt gtgacagaag taatc
//
LOCUS       DADVXK010000281         5636 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.135, whole genome shotgun sequence.
ACCESSION   DADVXK010000281 DADVXK010000000
VERSION     DADVXK010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.135"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            155..619
                     /locus_tag="KB909_002991"
     CDS             155..619
                     /locus_tag="KB909_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6838928.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            603..1232
                     /locus_tag="KB909_002992"
     CDS             603..1232
                     /locus_tag="KB909_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6838929.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            1586..3064
                     /gene="msr(C)"
                     /locus_tag="KB909_002993"
     CDS             1586..3064
                     /gene="msr(C)"
                     /locus_tag="KB909_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6838930.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            3111..3557
                     /locus_tag="KB909_002994"
     CDS             3111..3557
                     /locus_tag="KB909_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6838931.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3756..4271)
                     /locus_tag="KB909_002995"
     CDS             complement(3756..4271)
                     /locus_tag="KB909_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6838932.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            4388..5590
                     /locus_tag="KB909_002996"
     CDS             4388..5590
                     /locus_tag="KB909_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6838933.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1751 a          942 c         1199 g         1744 t
ORIGIN      
        1 tttccgttca ttctacaaaa aatttctttt ctctatactt ttctattgag agcgtttttt
       61 ttattacaca gctgattctt tgactttttt ctttttttat tctattattg acaagtcaat
      121 cgttgacgag tcaattatta gaaaggagga aattatgtct ttagaagaga ttagtcacct
      181 tttatatcaa atcaaattag ccgatcaaaa aatcgtccag atctttgaag aaaatatcgg
      241 tataagtctt actagatacg agatcatgat gagactgaaa gaagaaaatc cattgctaca
      301 aagcagtttg caagaaaagt tgcagattga tcaaggagca gttactcgtc atctgaaggt
      361 attggaagca aatggctatg tttcgcgtca gagaaatcct cagaacaacc gggaagtgta
      421 tgtagcgcta acagaaaaag cccagaagaa aatcaagcat tgtgaaatgg accataaaga
      481 tacaggttcc gtgctatccc cggctttcag cgatgtagaa atgaaacaat ttctaacact
      541 tttagataaa ttgaataccc aactttgcaa tataacaaca gaaacgaaag aggttaataa
      601 taatggaaca aaaaaatgat ttttcaacaa ttatgactgg tagaagatcc gttcgcgtat
      661 atgatgaaac atacaaaatc ccacacgaag aaatgctgga aatgatcaaa gaagcgacga
      721 ctgcaccttc ttctgtcaat atgaaaccat ggcgctttgt ggtcgctgaa agcgaggaag
      781 caaaagaaat cttgcgtcct ttgatccgtt tcaatacgag acaaaatgat acttcttctg
      841 caatggtcat gatttttggc gatatgcaat gttacgaata tggcgaagaa atctacaacc
      901 aagcttacga atcagggaag atgccaaaag aagtcagaga tcaacaatta gctgcgatca
      961 ttccttatta caagagtttt tcaagagaag aaatgaacga tgtagtcaaa gtcgattcta
     1021 gcttagcggc tatgcaattc atgttagttg cgcgtgatca tggctatgaa acaaatccaa
     1081 ttggtggatt cgaagcagat cagttggcag aggcatttgg tttggataaa gaccgttatg
     1141 ttccagttat tattttatca ataggaaaag cggtagaaga aggttacgag tctgttcgtt
     1201 tagcaccaga aaagatcact atgttcgaat aaaaggtttt cagttactat tcagtagcta
     1261 ttgctttttt tgaatcgtgt gtggtaacct aataaaaaag gaggtcggaa aaatgactgc
     1321 atcgatgaaa ttacgtttcg aacttttgaa taacaactaa ataaattcaa aagacatgta
     1381 taaacaacaa tttcatggat ggagtatgtc cattttttcg aacgacagta gaataggtga
     1441 aagctatgac agatttggtg atttagtcat agttatttcg ttcagagtag gaaaagatgt
     1501 gatgcagttt ttttgcaaac agatttttct gctctttttt agtatcgata attgttgttt
     1561 tacatgaaat aggagtgtaa aacatatgga aaatttagca gtaaatataa caaatctaca
     1621 agtcagcttt ggcaaccagc tagaactatc tattgattct cttcgtgtct atcagcaaga
     1681 tcgtataggg atcataggag aaaatggtgt cggtaaatcg actttgctca aactaatagc
     1741 cggtgaactt tttcccgatc atgggaaaat ccaaacagag atcaccttca actacctgcc
     1801 tcaattaacc tatctcgctg aagcaaagga cctaaatttg gaattagcca gtcatttcca
     1861 gttaagactg gaagaaactt cagagcggaa atggagcgga ggggaagaac gaaagatcga
     1921 gttgatacgt cttctttctt cttatgaaca agggatgctt ctagacgagc caacaaccca
     1981 tctagataga aaaagtattg atcgactgat tgaagagctt cgttattatt atggtacgct
     2041 ggtttttgtt agtcatgatc gctattttct agatgagcta gcatcgaaaa tctgggaagt
     2101 aaaagacgga gaaatccgag agttttcggg gaattatagt gcctatctca ctcaaaagga
     2161 attggagaaa aagactcagc tacgagaagc agagtcgatc atgaaagaga aaaaacgatt
     2221 ggaaaaatcg atccaagaaa agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa
     2281 aaagaaaaag caacaaatca gactggatcg gttgtcttcc tctaaacaaa aagacagtgt
     2341 acaaaaagcc atccaaaaga atgcgaaaac attagagaga agactccaaa aaataggaga
     2401 aacaaccaag ccgcagcaga tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact
     2461 ccacagccgc tatcccatca tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt
     2521 actggtaaat ggtgattttc agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa
     2581 tggttcaggt aagacaacct tattagaaca tatccgcaaa caaggagaag gaatccttct
     2641 ctctccgaaa gtaagctttc aagtatatca gcaaaagggt tatcaaatga catctgaaga
     2701 atccatcatt cgttttgtca tgagacaaac agagttttca gaatcgcttg tccgtagttt
     2761 gctgaatcac ttagggtttg ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg
     2821 gggagaagcg acccgtctga cgattgcttt gctttttact aagccaagta atgtgttgct
     2881 gttagatgaa ccgactaatt ttattgatat ggcaacgatc gaagctttag agaagctaat
     2941 gcaaatatat ccgggaacga ttttgtttac ttctcatgat tcttactttg tcgagcgtac
     3001 ggctgatgaa gtttatgaaa taaaagggca gaaaataaaa aaagtactta cgagaaattt
     3061 ttaaatgtgc tacgatgatt ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa
     3121 ataaaaaaga aggaataatt tttacaacaa tgatgtgttt tttgatggtc ttggggatga
     3181 gcgcgtataa tttatggctg catcaagatc ttcatttatc aagtttgttg attggtctag
     3241 tgcctggatt cgtggtggct ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa
     3301 aaattgcctt taaactacca gtaaatccag aaagcaaggt ccaaatgatc ttaactattt
     3361 catgcttgat ggttttagga atggtgacat gtatgtcttt attcggtgtg atcatggaac
     3421 aaggaatacc tgatcaatta ttctctgctt atatgaatgc ttggaaaatg aatgtgattg
     3481 ccgctttacc gttgcagttg atcatcgttg gcccgctttc aagaagtgtg ctaaaagcaa
     3541 ttcaaagtaa tgaatgatgg aacactgtta tttgaaaaaa ggccttggca tgctttttgt
     3601 catagtctct tgaatgcagt tctagaaaaa tagtgatccg aacgataggt tttggcctgt
     3661 cgttcggatc gctttttctt ttccaactgt attgctcttt tattgaagat aatttgctct
     3721 tcaatagata tttctagaaa ggttctgttt atcccttact caaaaaactg ctgcatttgt
     3781 tctcttactt gctgacacca ttggagttcc tgctgacaaa gcataattct gcgctggatc
     3841 acaacataac gtccaaattc ttgtttcttg tctagcgaga ggtcattcaa ttttttttga
     3901 tttttttgca tgattttgtt cagctgttgt tctctagtga atagcagtcc agtagctgtt
     3961 gttttatcga gcgtcgaaaa agcatagatt tttgctagaa attcatcttt ttgcgtagga
     4021 gcgggagttt cctctttgat ccattcctct acaagagcac gtccttcatc agtcaagtgg
     4081 tagatctttt tttgagagtg ctcgtctttg tccaaaacgg tcacataacc ctgctggtct
     4141 aacttggcaa gcgttgtata gatctgactg tgatgggctt cccaaaaaat tgtgatcagc
     4201 tgcttcaatt catacccaga acgtggtttg gataaaagca cgcataataa tatataggct
     4261 aaagtattca taaaaatcct acctctcgtc ttattttctt tattatatca cagtaaagtt
     4321 tccacgtttt acatgtgcat attgacatgt aaaataaatc atgtatgatg ctaatagaga
     4381 gaaagggatg gaaatattgg agaatcaaat agatatacaa gaacaaacaa atgaagaaac
     4441 aaaggggaaa agttcagcgc tagttgtagc agctacctgt atgatcgctt ttatgggagt
     4501 gggtctagta gacccaatct taaaaacgat tgctgcacag ttaaacgcta cgccagctga
     4561 aacgaccctg ttatttacta gttacatgtt agtcactggt gtggtgatgc tatttacagg
     4621 tttcttatct agtcggatcg gtttgaaaaa aacattgatg acaggattgt ttatcatcgt
     4681 tgtattcgct ggtcttggcg gattatctgg gaatatcgga atgctgattg ggttacgtgc
     4741 cggctggggt gtcgggaatg ctttatttgt ctctactgct ttagcaacga tcgtcagtat
     4801 tttagttggt aacacagaaa aagcaatcat gatgtatgaa gcagcacttg gctgcggaat
     4861 ggctgttggc cctctagtcg gtggggtctt gggcagtggt tcatggcgtt atccattttt
     4921 tggggtagca tttttgatgt tttgcggttt tatagcccta gcggtacttt tacctgaaac
     4981 tgagaaacca aagagaaaag taggcctttg ggaaggtgtc aaagcgttaa gcaatcataa
     5041 acttcgttca gttggactaa tcgcattgtt atataatttc ggattcttta ctttacttgc
     5101 gtatgcgcca tttttattga ttggctattc tgaattagaa gtcggttttg tattttttgg
     5161 ctggggtgtg cttctggcta ttgcttcgat tttcgttgca ccggctcttg agcggaagtt
     5221 tacgacttat cggacaattt tagcagcatt tgtcttattc attatttgtt tgctgttatt
     5281 aggagctgga acttctatgc cagtccttgt accgatcagc attgtgttag caggattttt
     5341 ccaaggaatt atcaatacac tgttgacgac gattgctatg gaaataccag gtctgcaacg
     5401 aaacgttgct tcgtccagct atagttttgt ccgctttttc ggtggagctt tagcaccatt
     5461 tattgcaggt gtgattggtg aacatattgg tgaaagctat gcgttttatt ttgcaggtgc
     5521 cattgttctt atcagtgtat gttgtatcat ttatcaccgt aattattttg ctacaaatga
     5581 agaagaataa gaaatcagag gttgtgaaaa agctgtcctg catcaagtca taagaa
//
LOCUS       DADVXK010000282         4702 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.152, whole genome shotgun sequence.
ACCESSION   DADVXK010000282 DADVXK010000000
VERSION     DADVXK010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.152"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            194..1000
                     /locus_tag="KB909_002997"
     CDS             194..1000
                     /locus_tag="KB909_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBB6838934.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1018..1725
                     /locus_tag="KB909_002998"
     CDS             1018..1725
                     /locus_tag="KB909_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBB6838935.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1722..2693
                     /locus_tag="KB909_002999"
     CDS             1722..2693
                     /locus_tag="KB909_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBB6838936.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2686..3714
                     /gene="vanB"
                     /locus_tag="KB909_003000"
     CDS             2686..3714
                     /gene="vanB"
                     /locus_tag="KB909_003000"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBB6838937.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3720..4328
                     /locus_tag="KB909_003001"
     CDS             3720..4328
                     /locus_tag="KB909_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBB6838938.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4394..4567)
                     /locus_tag="KB909_003002"
     CDS             complement(4394..4567)
                     /locus_tag="KB909_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838939.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1329 a          986 c         1245 g         1142 t
ORIGIN      
        1 gatagaatga ttttctatca gtcctagaaa ttatagagcc gattttgacc gacaggtata
       61 accctgccgg tctttttttg ctgctacagg aaaactacag actggctaca gggaaagtac
      121 agatgcgctt gccataataa caatcgtacc agccacaaat cgtagtttta ttgcaaagga
      181 ggcattcgat caaatggaaa aaagcaacta tcattccaat gcggatcatc acaaacggca
      241 tatgaaacaa tccgtggaaa agcgggcttt tctatgtgcg ttcattattt cgttcacagt
      301 ctgcacgctg tttttggggt ggagactggc ttccgtattg gaggcaacac agataccgcc
      361 catccctgca actcatacag gcagcagcac tgacgtagtg gagaatttgg aggaaaacgc
      421 tcttgccacc gccaaagaac agggagatga acaggaatgg agcctgattt tagtgaacag
      481 gcagaacccc atccccgcac agtacgatgt ggagcttgag caactatcaa atggtgagcg
      541 gatagatatt cggatttctc cctatcttca agatttgttt gatgccgcaa gaactgatgg
      601 agtttacccg attgtcgcat ccggataccg aacaacagaa aaacagcaag aaattatgga
      661 tgaaaaaatt gccgaatata aggcgaaagg ctacacctct gcacaggcta aagcggaagc
      721 agaaacttgg gtggccgtgc cgggaacgag cgagcatcag cttggtcttg ctgtggatat
      781 caatgcggac ggaattcatt caacaggcaa cgaggtttat agatggctgg atgaaaacag
      841 ctatcgtttt ggttttattc gtcgctaccc accagacaag acagagataa ccggtgtgag
      901 caacgagccg tggcattacc gatatgttgg catcgaagct gccacagaga tgtacaacca
      961 aggggtttgc cttgaggaat atttaaaacc agaaaaatga gaaaaggatg ttatgttatg
     1021 gacagaaaaa gattgacaca gcgtttcccg ttcctgcttc caatgagacg ggcgcagaga
     1081 aaaatgtgct tttatgcggg aatgagattt gacggctgtc gctatgcgca gacgataggg
     1141 gaaaaatcgc tttcccattt gctctttgaa acggattgcg cattatacaa ccacaatacc
     1201 ggatttgaca tgatatacca ggaaaacaag gtgttcaact taaagctggc agcaaagacc
     1261 ttaaacggct tattgataag accgggggaa accttttctt tctggttgtt cctgcatacg
     1321 ccattgacaa ttatccagcg cagaggtcac gaagtaaagg agtttccaga gccaaacagt
     1381 gacgagatta aaggggtgga tgcaaccatt tcagagggct ggattgattt aaaagtgcga
     1441 aacgataccg actgcaccta ccaaatatgg gtgaccttag atgatgagaa aatcatcggt
     1501 caggtgttcg ccgacaaaga gccccaagca ttatacaaaa ttacaaatgg cagtatccag
     1561 tatgtccgtg aaagtggcgg gatttatgaa tatgcccagg ttaaacggat gcaagttgcc
     1621 ttaggtaccg gggaaataat agattgcaag ctgctttata caaacaaatg caaaatctgt
     1681 tatcccctcc cggaaagtgt ggatattcag gaggagaacc aatgagaaaa agtgtgggca
     1741 ttactgtttt tggatgcgaa caggatgagg caaatgcttt ccgcgcttta tcgccggatt
     1801 ttcatattat ccctacgctg attagcgatg cgatatcggc agacaacgca aaattggccg
     1861 ctggcaatca atgcgttagc gtaagccata agtccgaggt ttccgaggcg acaattcttg
     1921 cgctgagaaa ggtcggggta aaatacattt ctacccgcag catcggctgc gatcacattg
     1981 atacgactgc cgccgagaga atgggaatct cggttggcac ggttgcgtat tcgccggaca
     2041 gcgttgcgga ttatgctttg atgctgatgc tgatggccat acggggtgca aaacccacca
     2101 tgcacgccgt ggcgcaacaa gatttcagat tggatcgtat ccgggggaaa gaactggggg
     2161 atatgactgt gggagttatt ggaaccggcc atatcgggca agcggtcgtc aaaaggctgc
     2221 ggggatttgg atgccatgtg ctggcctatg ataacagccg aaaaatggat gcagattatg
     2281 tccagcttga tgagcttcta aaaaacagcg atattgttac gctccatgtg ccgctttgtg
     2341 cggatacccg ccatctgatc ggtcagaagc aaattggaga gatgaagcaa ggcgcatttt
     2401 taatcaacac cgggcgcgga gcgcttgtcg ataccggggc gctggtggag gcgttggaaa
     2461 gcggaaagct gggtggtgcg gcactggatg tgttggaggg cgaggatcag tttgtttata
     2521 ccgattgctc gcagaaagtg cttgaccatc cctttttgtc gcagctttta aggatgccga
     2581 atgtgatcat cacaccccat acggcgtact acactgagcg tgtgctgcag gatactacag
     2641 aaaaaacaat caggaattgt ctcaattttg aaaggagttt acagcatgaa tagaataaaa
     2701 gtcgcaatca tcttcggcgg ttgctcggag gaacatgatg tgtcggtaaa agccgcaata
     2761 gaaattgctg cgaacattga tacggaaaaa ttcgatccgc actacatcgg aattacaaaa
     2821 aacggtgtat ggaagctatg caagaagcca tgtacggaat gggaagccga cagtctcccc
     2881 gccatactct ccccggatag gaaaacgcat gggctgcttg tcatgaaaga aagcgaatac
     2941 gaaacacggc gtattgatgt ggctttcccg gttttgcatg gcaaatgcgg ggaggatggt
     3001 gcgatacagg ggctgtttgt attgtctggt atcccctatg tgggctgtga tattcaaagc
     3061 tccgcagctt gcatggacaa atcactggcc tacattctta caaaaaatgc gggcatcgcc
     3121 gttcccgaat ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc gcttacctac
     3181 cctgtctttg tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa agtaaacggt
     3241 acggaagaac ttaacgctgc gatagaagcg gcaggacaat atgatggaaa aatcttaatt
     3301 gagcaagcga tttcgggctg tgaggtcggg tgtgcggtca tggggaacga ggatgatttg
     3361 attgtcggcg aagtggatca aatccggctg agccacggta tcttccgcat ccatcaggaa
     3421 aacgagccgg aaaaaggctc agaaaatgcg atgattacag ttcccgcaga cattccggtc
     3481 gaggaacgaa atcgggtgca ggaaacggca aagaaagtat atcgggtgct tggatgcaga
     3541 gggcttgccc gtgttgatct ttttttgcag gaggatggcg gcatcgttct aaatgaggtc
     3601 aataccctgc ccggttttac atcgtacagc cgctacccac gtatgatggc cgccgcagga
     3661 atcacgcttc ctgcactgat tgacagcctg attacattgg cgttaaagag gtgataagta
     3721 tggaaaatgg ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg gatgccaagt
     3781 acgccacatg ggataacttc acaggaaaac cggtggatgg gtatgaggtg aatcgcatca
     3841 tcggcacaaa ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg gctgcgcttg
     3901 gctatggctt gcttttatgg gatggatatc ggccaagaac tgcggtggac tgcttcctgc
     3961 gttgggcagc gcaaccggag gacaatctca caaaagaaaa attttacccc aatatagagc
     4021 gagccgagtt gattacaaag ggttatgtgg cctcacaatc cagccatagc cgtggaagcg
     4081 caattgatct tacgctctac cacctggata caggggaact tgtttcaatg ggaagtaact
     4141 tcgattttat ggacgaacgg tcgcatcata cagcaaaagg gataggggat gcagaggcac
     4201 aaaatcgaag atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct tatcgctttg
     4261 aatggtggca ctataagttg attgatgagc cataccccga tacctatttt aattttgccg
     4321 tttcataatg aaagtattgg ttttgtatca gattttggat ttgataaaat ctatgctggt
     4381 catggacaat cttttactgg aaagtggtta aagcatcttt tgtaatacat tgcaaattat
     4441 agtattcaat ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag acctttccca
     4501 cgcccatttt gtattttgct ggcggcggtt ttgagaaatc aaggccgccg ttcttttctg
     4561 gcagcaaaag gtgtggcggc ccataggagg atgccgctat gctgttttgc tattgccatg
     4621 ctctaatcca cttccaccac tcaaaaaaag ccttgcccct ccatgaactg aaccccaaaa
     4681 gttgaactat ttaatggact gt
//
LOCUS       DADVXK010000283         4622 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.154, whole genome shotgun sequence.
ACCESSION   DADVXK010000283 DADVXK010000000
VERSION     DADVXK010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.154"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..349
                     /locus_tag="KB909_003003"
     CDS             <1..349
                     /locus_tag="KB909_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6838940.1"
                     /translation="IESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQD
                     SLFTKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRF
                     AFRAKSKKTSPIK"
     gene            509..2395
                     /locus_tag="KB909_003004"
     CDS             509..2395
                     /locus_tag="KB909_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6838941.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2407..3354
                     /locus_tag="KB909_003005"
     CDS             2407..3354
                     /locus_tag="KB909_003005"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6838942.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3374..3901
                     /locus_tag="KB909_003006"
     CDS             3374..3901
                     /locus_tag="KB909_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6838943.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3964..4617)
                     /locus_tag="KB909_003007"
     CDS             complement(3964..4617)
                     /locus_tag="KB909_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6838944.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
BASE COUNT         1655 a          800 c          961 g         1206 t
ORIGIN      
        1 tattgaaagt ttagataact tgactgatat ttatgatgaa acgatggttc aattttttat
       61 ccagcaacgc aaacttgaag gaataaaaat gaactcgggg aatttgattt cttcgtggat
      121 gatccagcaa gatagtctgt ttacgaaaaa aatgctaaga ggttattatc ttgaaagaaa
      181 aatcattgat gaatacgaag ttgctgaaaa aatcacgacg ttttctgcga acagctatcg
      241 caggaatatc aatttgttag aatcttatac gatgaacaaa ccatctgata acttttcttt
      301 ccgatttgcg tttcgagcaa agtcaaaaaa aacgagtcca ataaaataaa aaggtaaaaa
      361 ttttcaagtt ttataaaaaa caaaacatat cagaacagga tcgaatcggt cctgttcttt
      421 ttttgagaac acaaaaagaa caaataccaa aaaaattttc ctgaagttca ctatttttat
      481 gatacaatat ccaagataag gagggaacat gttgaaagaa ttaaaagtaa ctgacctcaa
      541 aaaaacttat ggtgaaaaag atttgtttga ccagatttct tttttggtcc acgaaaaaga
      601 ccgtatcggg ttgattggga cgaacgggac gggtaaaaca agtctcttaa atattattgc
      661 cggtatcgat agcagcgacg gtgatcggca aacagtgttt tatccaactg attaccgtat
      721 tggttatctt tctcaagcag ctgaattttc cgatgaatta actgttctcc aagcagtctt
      781 tcaaggaaac agccccttga tccaaactgt tcgagcatat gaggaagcat tgatcgaact
      841 aggggaaaac ggagaagacc ctgatgtgca aaaacgttat gctaaagcag aagaacaaat
      901 gaataaagaa gatgcttgga ctacagatac caacgcaaag attattttgc aaaaattagg
      961 aatcagtgaa ttagataaaa aaatcagtac tttatcaggt ggtcagaaaa aacgagttag
     1021 tctggcgcaa gtgttgattg atgaacccga tttactatta ctagacgaac caacaaacca
     1081 tttagattat gaagcgatcg agtggttgga aaactatttg aaacaatacc gtggcgcact
     1141 attgatggtt acccacgatc gttattttct agatagagta gcaaaccgaa tcttcgaact
     1201 ttcatttgga aaattatacg agtataaagg aaattatgaa gcttacgtct tagaaaaagc
     1261 agaacgtgat cgtgtagaag tagaacaaga agaaaagcgc aagcggcttt ataaacagga
     1321 attagcttgg atgagggctg gcgtacaggc acgtggcacc aagcagcaag cacggatcaa
     1381 ccgtttcgaa gatctaaagg agaacttgta ccaagtaaac caagaagatg atttagagct
     1441 gaacctagcg acacaacgtt tagggaaaaa agtactggaa atcaaagatg gcagttaccg
     1501 tataaatgac caaacactgc tagaacattt agatttattg attcaatctc gggaaagact
     1561 aggtattact ggtaaaaatg gtgcgggaaa atcgacattg cttaatattc tagctggcag
     1621 aattcccctg gatagcggta caatgtctat cggtgaaacg gttcatcttg cgtattatac
     1681 acaagaaaat gaagaaatgg caccagataa acggatgatt gcttacttac aagaagctgc
     1741 tgaagaagca aaaacagcag atggcagtca aatcggagta gcagaattac ttgaacgatt
     1801 tttatttcca agatttatgc atgggacact gataggcaaa ctttcaggcg gagaaaaacg
     1861 ccggttattt ttgttgaaac tgctgattca gcaacctaat gttttattat tggatgaacc
     1921 gaccaatgat ttggacatag caacattgac gattttggaa gattatttta gaagttttcc
     1981 aggtgctgtg atcactgttt cccatgaccg ttatttcttg gacaaggtag cagataagtt
     2041 attagtattc caaggaaacg gaaaacaaga actttattac ggaaacatgt ccagttattt
     2101 actgaagcaa aaagagaccc agcagcctgc tgaaaaagcg aaaccaaaaa tacagagcaa
     2161 ggaacctgct gaaaagaaga aattatctta catggaacaa aaagaatggg aaacgattga
     2221 agatgagatt gcagaacttg aagaaaaaat ctcattgctc caagaagaga tgaatcatca
     2281 aggagataat ttcactcgat tacaagaatt gcaaaacgac gtatctgaaa cagaagcaca
     2341 acttgaagaa aaaatggcac ggtgggaata cttgagtgaa tgggtagaag attaggagga
     2401 aaaaggatgg aacaagcgta tcttgactta ggaagaaaat tgttggaaga agggcatcgt
     2461 aaagaagaca gaacaggcac aggcacatta agcttattcg gataccaaat gcggtttgat
     2521 ctgcaaaaag ggtttccttt gttaacaacg aaacgagtac cttttggatt gatcaaaagc
     2581 gaattgcttt ggtttttaaa aggagatacg aatatccgct atctattaca aaataaaaac
     2641 catatttggg atgaatgggc atttgaacgc tacatcaaaa gtccagacta taatggacca
     2701 gatatgactg attttggcca tagatgtttg acagatcctg aattcaatga agaatataaa
     2761 aagcagagca agcttttttg cgagaagatc ctaaccgatg attcctttgc tgaaacatac
     2821 ggcgatcttg gacacatcta cggctatcaa tggcgtcact gggaaacaaa agacggtggc
     2881 tttatcgatc aaatcaaaca agtgatcgaa gcaatcaaaa agactcctga ttctagaaga
     2941 ttgatcgttt ctgcatggaa tccggaagat gttcctagca tggctttgcc tccttgtcat
     3001 acgatgtttc aattttatgt tcaagaggga cggctaagct gccaattgta tcaacgcagt
     3061 ggggatgtgt ttctaggcgt tccgttcaac attgcaagtt atgcgttgct gactcaccta
     3121 attgcacatg aaacaggttt agcggttggc gaatttgttc acacattagg agatgctcat
     3181 ctttatatca atcatatcga acaaatgaaa gaacaattga gccgagaaat acgcgcattt
     3241 ccgactttag ttttgaatca ggaaaagcag tcagtatttg attttgagat ggaagatatc
     3301 caattagaag gatatgaccc acatccggcg atcaaagctc ctatcgctgt ttagaatcag
     3361 aaaggatgag aaaatgttag ctgcaatttg ggcacaggat gaaaacggat tgattggaaa
     3421 agaagaccgt cttccttggc gtttgccaaa tgatctgaaa ttcttcaaac aaatgacaga
     3481 agcaaataca ctagtgatgg gacgaaaaac attcgaaggg atgggtagcc gtccgttgcc
     3541 gaatcgtcag acgattgttt tgacgagaga ttcttcctat aaagcagaag gcgtgcatgt
     3601 catgcatagt gtggaagacg tgcttgctct ggaaaaagaa acagacggta tctttttcat
     3661 cgctggaggg tcagctgttt atcaagaatt tctgccattt tgtacgatat tataccgtac
     3721 agtcatccat catgtattcg atggagatgc ttattttcca cctgttgact ggtctgattg
     3781 gtcactgatc aatactagtc aaggagaaat ggatgaaaaa aatcgttatc cgcatcaatt
     3841 tgaaacgtat cagcgtaatg agaatcctgt aaaaagcggg acaggcgaat tgacgatata
     3901 aaaaagctat ggatagacta gctgttattt agagctgtcc catccatagc tttatttttt
     3961 ttattaagta aagaataaaa cagagaagta cataaaacct gcacctaaca taacaaacaa
     4021 atgccaaaca acatgcatat agcggataga attcaagcta taaaagaatg cgcctatcgt
     4081 gtaagaaagc ccgcctgcta ccatcaaaat aacaccagtc attccaagag agtgataaag
     4141 aggaacagca gccacgacac agagccaccc cataaaaata tagatgatcg tagatacttt
     4201 tgatactctc tcccgtttat gcaacgtcaa cgctttatat ataatgccaa gaatcgcaaa
     4261 caaccagatt aatacaaata aagtccaacc tagccatcct cggatactca gcaaacaaaa
     4321 aggagtataa cttcctgcaa tcaaaagaaa aatcgaacta tgatcgaata cttggaacac
     4381 cttttttgct tttgtaaaaa tcaatgaatg aaacaaagta gacgttaaaa ataaaagaat
     4441 catcatcgat ccatagatag cataagagac aatatggagg gaggaatgca agtgggcacc
     4501 ttttactaaa agaaccacta gtcccgcgat actcaatcca gtcccaattc catgggtgac
     4561 tgcattaaac acttcattta atatttcata cgttcgatta aatttcgttt tttccatgaa
     4621 aa
//
LOCUS       DADVXK010000284         3337 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.172, whole genome shotgun sequence.
ACCESSION   DADVXK010000284 DADVXK010000000
VERSION     DADVXK010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.172"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            218..715
                     /gene="dfrG"
                     /locus_tag="KB909_003008"
     CDS             218..715
                     /gene="dfrG"
                     /locus_tag="KB909_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6838945.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(787..2739)
                     /locus_tag="KB909_003009"
     CDS             complement(787..2739)
                     /locus_tag="KB909_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6838946.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2746..2982)
                     /locus_tag="KB909_003010"
     CDS             complement(2746..2982)
                     /locus_tag="KB909_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838947.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         1034 a          579 c          546 g         1178 t
ORIGIN      
        1 ttttcatttt aacttacata ccaaattaca tacaaaatga tttataaaat gcaattgaaa
       61 atgataattg aatgaaaatt tgtgattttg tggtattatg ataatataac ttatagaaaa
      121 aattgcttat tcaactaacg ggcaggataa tgagaaaagg ttttttgata gaaataagaa
      181 attagatggt aaattagtta aaaaggctgt gttataaatg aaagtttctt tgattgctgc
      241 gatggataag aatagagtga ttggcaaaga gaatgacatt ccttggagga ttcccaagga
      301 ctgggaatat gttaaaaata ctacaaaggg acatccgata atattaggta ggaagaacct
      361 tgaatcaatc ggaagagcct tacctgacag aagaaatatt attctgacga gagataaggg
      421 gtttaccttt aatggttgtg aaattgttca ttcaatagaa gatgtttttg agttatgtaa
      481 aaacgaagaa gaaattttta ttttcggagg agaacagatt tataatttgt ttttccctta
      541 tgttgagaaa atgtacatca caaaaataca tcatgaattc gaaggagata ctttttttcc
      601 agaagtgaat tatgaggaat ggaatgaggt atttgcccaa aaagggataa agaatgataa
      661 aaatccgtat aactactatt ttcatgtata tgaaagaaaa aacttattga gttaacgggt
      721 gcgttaattg aagaagaaca gtaaagataa agcacaagag cttgggatta ctccaagctc
      781 tttttgtcat ttgaaataaa ttatatcttt ccaatcaaat tgtttatctg taatccctaa
      841 tctttgagca ggtgtcaaaa cctttttatc cgctgattta aaagggcgac aaaagttgta
      901 gtaagttctt agaattgtaa tcgcaaattg agcatacttc ggattgaagt tagcgtaaat
      961 atagctcttc ttatcaccac gagctgttgt taatggtctt tcaagagatg atatataacg
     1021 tcttatctgt tgaataaagc tattggtcga atggtcatta acatttaata gcatctttgc
     1081 gatttcgttt ggttccagag cagataaatc cgttctacaa tcaactgaat aaaatccttt
     1141 atccttagtg gctaatggat gtttgatagg gttatcggca tatttgcgat atctttctcc
     1201 atctttacta atagcctctt cgtggaattg atgacttgtt agtaattcag ttagataatg
     1261 agatgccaaa gtccgtagaa actttgtttt gaatcctctg atatctcccc aatcgagcag
     1321 ttctgctttt gcttgtccga attcttttaa gcattgtttt ctgcttttcg tcttgttaac
     1381 ttggcaaata aaatgatgtg catcgctcaa ccttaattct ttcgtgaata ctctataaaa
     1441 ggcgtttcta atagagaagt catcatcact aatcattcgc cattcgtcgg cattaaccat
     1501 ttgtttaatt aaccaatagt gagcagttgt agtataagga gcatcaacat ttaaaccatc
     1561 gacaaatcta ctcctattag taattttccc taattcgtga agataagcat tcctattttc
     1621 gctatcgtta gcggatggtt cttgtggata ataagaccaa tctaacctat catttttacg
     1681 actaaaagta ttgagatggt cttctttgaa ttttcttgta tcttcattta attcatccat
     1741 tgaaatattc caatcatagg caacatcaga acggaacaca tatcttgata agacctcagc
     1801 agatacaact atatacgttt gcatattaag gtcttcaaac cccgtatatt tctttgaacc
     1861 ttgtcctttc ttacggacgt tatttaggta gtagtgcatc ttgtccgtat taagccacat
     1921 ctcgttaaat ttctttgttt gaaggggttg tgtctcatat cgttctaaaa actccaaaca
     1981 acgcctatac agccactcca gcttatgata gtaggttcca actccaattc ctaaaatatc
     2041 acaagtacga ctgactgaaa cccttccaac aaccatctta gcgaacattg gaagaatggt
     2101 gttcttttgt tggtgataag tagtggtttc ttctcttttt ggtagaacat tagtgaactt
     2161 cttacacgcc ttacattgat agcgttgaga tttgccccta cttttccccc ttttgtaaaa
     2221 ttgcttcggc tcattgaatg gggttgattc ttcttccgag cagccttctt tatgaaattg
     2281 ataatctggc tcaacatctt ggatgctatt gatttctata aggcgtttaa tttcttcaac
     2341 aacagaccaa ttagataaag gggttactgt acagttttgc gatacacctc tgccaatagg
     2401 attgtcattg cagtacatac ctttatgacc tttatctttg gaactaccag tcattttata
     2461 tcgacttggt ttccctttta catctttgaa tttgtgctgt tctttcccaa aattacaaca
     2521 aaacggattg atgcagtaat tatattgaat gggatattca gaaccgttcc atttaaaaga
     2581 cgttggcaag aacaacattt tgttatacct tgttgcaaat cgttttggag ttaataaatc
     2641 atattgttta gccctatctt ttaattcttc gtttgaaatc ggaattttaa catctacaat
     2701 ttcatcttcc ttcgtggcta atcttttaag cttggtcatt gtctatcaac ccactctatc
     2761 tttgataccc attttttcaa caatccgctt attacttcgc ttgttggcaa tccattcaat
     2821 aaacttctta tcgtctaaaa tgttcaataa gaattcatcc actgcttcgc tttcagtacg
     2881 ctctgcatat tcagcgtatt gcttaactat cacccttact tgctctgata tttcccaatc
     2941 cacagactta gcgttcttat tttttggctc aagaaattgc ataggaaaat gcaccccttt
     3001 ttgcttagta aattgtaacc attttaacac accaatttgc attcctacaa taattatttc
     3061 acgttcgcat ttttatatac attttaactt acattttgtg gtgtaaatta acaacaaacg
     3121 ttgatttaac aataaaaaac gagtatcaaa ttcagttgca atttgatact catttaggtt
     3181 tacattttca ctttttgtac tccaaaactg aactacttaa atctatactg ctgcctcttt
     3241 tttttagtac atgtccttca tcttcgcagg aagtgccaat atgattttaa gaaaggtaat
     3301 agacaaaaag tcaaaaagat aaaacagagt ttcttct
//
LOCUS       DADVXK010000285         3276 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.176, whole genome shotgun sequence.
ACCESSION   DADVXK010000285 DADVXK010000000
VERSION     DADVXK010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.176"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            61..246
                     /locus_tag="KB909_003011"
     CDS             61..246
                     /locus_tag="KB909_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6838948.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            404..571
                     /locus_tag="KB909_003012"
     CDS             404..571
                     /locus_tag="KB909_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6838949.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            1189..1848
                     /gene="vanR"
                     /locus_tag="KB909_003013"
     CDS             1189..1848
                     /gene="vanR"
                     /locus_tag="KB909_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBB6838950.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            1851..3212
                     /gene="vanS"
                     /locus_tag="KB909_003014"
     CDS             1851..3212
                     /gene="vanS"
                     /locus_tag="KB909_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6838951.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
BASE COUNT          978 a          632 c          831 g          835 t
ORIGIN      
        1 cattttgttt cttttattct tcgagcaaaa gaattataat gtaccctgtg gaggtgtact
       61 atggactaca tgacgttgaa agaggcaggc gagaaatggg gtgtgccccc acgatggata
      121 aactactatt gtgctgcggg acgcatcccc ggcgctgtaa agatggcgac gatctggctc
      181 attcccaaaa ctgcggaaaa gccgattgac aggcgtacaa agaaaggaaa ggcggttact
      241 gaatagtata atgaaaccgg cgcattttgg atatggtttt gaagagagag aaagcatggt
      301 attttgtcac ggaaaaacta taagatgata gatggcaggc tgctccagac cgataaaaag
      361 tattctcatc tgaaacagaa agaaaagatt tacacatgga tgtatgaaga agcgaaactt
      421 tatcatgaca gaaatggaaa atgcccgaaa caaagacgag gaagctgctg ctgtatcagc
      481 cgtatatggt agaattgaaa aggccggcat ctggattctt tatggtgaag tctccagaca
      541 ttggataact gctggtctaa tgcgcctttg agtatggggt gattgatttt aataccgggg
      601 aggtacggct ttttgaggaa aatattctgg gatttacatt tggcgattat tacatttcct
      661 gtaactgcaa ggacacggat gatgaagata tgaggaatat agacttgctg attttctact
      721 gtcttgaacg gtattaggac tgaatctgct gcgcggagtg cggcaagagc gaccggaggg
      781 agtacacaca ggccctgcct gtgtgaaaag ccataccgca aggtgcattc gcaaaaaaga
      841 ggccgcgcat tttgctgagg cttggggtgt ccccaacaag caaaacgaga acgccgcagg
      901 cgggcaagtg gtggatcaga atatccgtaa aggatattct gatccattgc ttgccagtat
      961 tatcgggatg ttttgacaac cgctgtaatc gaaacatccc aaacattaag aaggtgttaa
     1021 ttattattat cttgatttaa ttcgtttaaa ccaataatat agatacatac accatgaaaa
     1081 gaagcgagta tcccaatgac ggatgattaa aatccgaaaa gaaatcgctt tgaaactaca
     1141 gggaaactac agactgttat gttatcttct taaaatggag ggatttttat gtcgatacga
     1201 attctacttg tcgaggatga tgatcatatc tgtaatacag taagggcgtt tctggctgag
     1261 gcaggatatc aggtggatgc ctgcacagat ggaaatgagg catacaccaa gttttacgaa
     1321 aacacttatc aactggttat tcttgatatt atgctgcccg gtatgaacgg gcatgaactt
     1381 ttgcgtgaat ttcgtgcgaa aaatgatact cccattctga tgatgacagc cctgtcggat
     1441 gacgaaaacc aaatccgggc gtttgatgca gaggcagacg actatgtaac aaagccattc
     1501 aagatgcaga ttttactaaa gcgggtggaa gccctgctgc ggcgcagcgg tgcgctggca
     1561 aaggaaatcc gtgtcggcag gctgacactt ctgccggagg atttcacggt actttgtgac
     1621 ggtacagagc tgcccctgac acgaaaagaa tttgaaatcc ttttgctgct ggtgcagaac
     1681 aaaggcagaa ccttaacgca tgaaatcatt ttgtcacgta tatggggata tgactttgag
     1741 ggtgatggca gcacagtcca cactcatatc aaaaatttgc gggccaagct gccggaaaat
     1801 atcatcaaaa ccattcgcgg tgtaggatac cgattggagg aatcataata atggaaagaa
     1861 aagggatttt cattaaggtt ttttcctata cgatcattgt cctgctactg cttgtcggtg
     1921 taacagcaac actgtttgca cagcaatttg tgtcttattt cagagtgatg gaattacagc
     1981 aaacagtaaa atcctatcag ccattggtgg aactgattca gaatagcgat aggcttgata
     2041 ttcaagaggt ggcagggctg tttcactaca ataaccaatc ctttgagttt tatattgaag
     2101 ataaagaggg aagcgtactc tatgccacac caaatgccaa tacatcaaat agttttagac
     2161 ccaactttct ttatgtggta catagagatg ataatatttc gattgttgct caaagcaagg
     2221 caggtgtggg attgctttat caagggctga caattcgggg aattgttatg attgcgataa
     2281 tggttgtatt cagcctttta tgcgcgtata tctttgcgcg gcaaatgaca acgccgatca
     2341 aagccttagc ggacagtgcg aataaaatgg caaacctgaa agatgtaccg ccgccgctgg
     2401 agcgaaagga tgagcttggc gcactggctc atgatatgca ttccatgtat gtcaggctga
     2461 aagaaaccat cgcaaggctg gaggatgaaa tcgcaaggga acatgagttg gaggaaacac
     2521 agcgatattt ctttgcggca gcttctcatg agctaaaaac gcccatcgcg gctacaagcg
     2581 ttctgttgga gggaatgctt gaaaatatcg gtgactacaa agatcattct aagtatctgc
     2641 gcgaatgcat caaaatgatg gataggcagg gcaaaatcat ttccgaaata ctggagcttg
     2701 tcagcctgaa tgatgggaga atcgtaccca tagctgaacc gttggacata gggcgcacgg
     2761 ttgccgagtt gctgcccgat tttcaaacct tggcagaggc aaacaaccag cggttcgtca
     2821 cagatattcc agccgggcaa attgtcctgt ccgatccgag gctgctccaa aaggcactat
     2881 ccaatgtcat attgaatgca gttcagaaca cgccgcaggg aggcgaggta cggatatgga
     2941 gtgagcctgg tgctgaaaaa tgccgccttt ttgttttgaa catgggcgtt cacattgatg
     3001 atactgcgct tccaaggctg ttcaccccat tctatcgcat tgatcaggcg cgaagcagaa
     3061 aaagtgggcg aagcagaaaa agtgggcgaa gcggtttagg acttgccatc gtacaaaaaa
     3121 cgctggatgc catgagcctc cagtatgcgc tggaaaacac ctcggatggc gttttgttct
     3181 ggctggattt accgctcaca tcaacattgt aaatatttaa aacttaaatg attttgggct
     3241 ctttgtcaaa taggactgat agagtgagat aagaac
//
LOCUS       DADVXK010000286         2454 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303643-18
            SAMEA8426467-rid11941643.guided.198, whole genome shotgun sequence.
ACCESSION   DADVXK010000286 DADVXK010000000
VERSION     DADVXK010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426467
            Sequence Read Archive: ERR5555432
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005880.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005880.1
            Genome Coverage       :: 163x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:26:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,018
            CDSs (total)                      :: 2,953
            Genes (coding)                    :: 2,888
            CDSs (with protein)               :: 2,888
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 26 of 65
            Pseudo Genes (incomplete)         :: 29 of 65
            Pseudo Genes (internal stop)      :: 16 of 65
            Pseudo Genes (multiple problems)  :: 5 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426467-rid11941643.guided.198"
                     /isolate="303643-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            1..738
                     /gene="erm(B)"
                     /locus_tag="KB909_003015"
     CDS             1..738
                     /gene="erm(B)"
                     /locus_tag="KB909_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6838952.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1001..1864)
                     /locus_tag="KB909_003016"
     CDS             complement(1001..1864)
                     /locus_tag="KB909_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6838953.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(1866..2138)
                     /locus_tag="KB909_003017"
     CDS             complement(1866..2138)
                     /locus_tag="KB909_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6838954.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2155..2364)
                     /locus_tag="KB909_003018"
     CDS             complement(2155..2364)
                     /locus_tag="KB909_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6838955.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          727 a          448 c          395 g          884 t
ORIGIN      
        1 atgaacaaaa atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa
       61 ataataaaac aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa
      121 gggcatttaa cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac
      181 agtcatctat tcaacttatc gtcagaaaaa ttaaaactga acactcgtgt cactttaatt
      241 caccaagata ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggaat
      301 attccttacc atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct
      361 gacatctatc tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca
      421 ctagggttgc tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa
      481 tgctttcatc ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca
      541 gatgttccag ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga
      601 gaatatcgtc aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta
      661 aacaatttaa gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta
      721 tttaacggga ggaaataatt ctatgagtcg cttttgtaaa tttggaaagt tacacgttac
      781 taaagggaat gtagataaat tattaggtat agggcacctc taataactac caattaattc
      841 acctcaaaat gaaattagaa aaaaacagcg aaatttttaa atctatttct tatcgataca
      901 aattcctcgt aggcgctcgg gaccccaaca tgaggaaatg tttttataaa aaaagagtag
      961 ttaccgtttt ttggtaacta ctcttttcct tttttaaggt ttaaatacct ggaagtttag
     1021 gtgttttggg tattggtggt gtaggtagct gcaagctttc cattttttgt tgaattgctt
     1081 taaattcagg ggtttcttgg tgttgatttt gaaccatttt ttgctctatt ctctccaaag
     1141 tcggttgaat ttctttccct gatactttac gatttaattc tctttctaag gtctctttcg
     1201 gactaatgga aggcgtttct aagcttgaat agagtttcac tccttctcta ttgtaaagcc
     1261 ttatatcgct aaataagccc gttttatgaa gggtttctaa attggtcggt aagtttttga
     1321 caacaatatc atgcgcttgt tttggtgttg ccctagctgt cattggatca tctgcataca
     1381 tggtttcata tcgttcaatc gttcctaagt atgattcaat tttcggtact gccatgacgt
     1441 atatttttgt ttcataacct ttagattgaa gcattgtggc tgtttgaatg ggaacgtctg
     1501 ttgttcgtcc tgttccttca atcactaaat tatagccttg atcgcttaaa cggctaataa
     1561 gtgcttctgt catgcgattc gaataagggg taacgtgttt tactacgtct ttttcataga
     1621 gtttcactaa ttcgtcaaaa tttgggtgct gttgtttaaa ggtatcatta tcaatgacaa
     1681 taacattccc ttgtgtttct tcaaaaattg ctgatcgcaa actggttttc cctgaccctg
     1741 gttgcccacc aagtaaaaaa gcggttggcg attcaaccgc tagtctattt ttagttagtc
     1801 gttcaacatt cttttctaaa cgatcttcaa attgcttttc ggtgaagtca gtaatattcg
     1861 ccatgttaag ccactttctc tttattcaaa atttgttttg aatattgatt cattgaccgc
     1921 caatactcat gaatagcttg taattcttca aatggttgtt gaaataaatc aacttcttgt
     1981 gccacttcta attgatttaa aagattcact tctagtaaac gagtattttt agtatctagt
     2041 tcatgattca aaacataatt taatacccga ttataaacac ttgccgataa ctcattaatg
     2101 atttcaattt caaatgtttt ttcatacgta actgccattt cattttcact ccttttaaag
     2161 tttgtcaggt aaatatttcc gtatatattc ttctaaggct tgatccataa cttcttttac
     2221 gtttccgcca ttctttgctg tttcgatttt tatgatatgg tgcaagtcgg cacgaacacg
     2281 aaccgtctta tcccccatta tatctttttt tgcgctgatt ggcgtatcat ttcgttttgc
     2341 tttctgtgcg cctaaatttc ccacgatcgc tcacttcttt ctatttcttc ttactattta
     2401 ttttatcatc acctatcaca aatcacaagt gatttgtgat taatcacttg tgat
//
